ple, in the case of acute hyperactive intoxication  delirium occurring in a man with a severe co-
caine use disorder, the diagnosis is F14.221 severe cocaine use disorder with cocaine
intoxication delirium, acute, hy peractive. A separate diagnosis of the comorbid severe cocaine
use disorder is not given. If the intoxication delirium occurs without a comorbid substance use
disorder (e.g., after a one-time  heavy use of the substance), no accompanying substance use
disorder is noted (e.g., F16.921 phencyclidine intoxication delirium, acute, hypoactive). 
Substance withdrawal delirium
ICD-9-CM. The name of the substance/medication withdrawal delirium  begins with the
specific substance (e.g., alcohol) that is presumed to be causing the withdrawal delirium. The