experienced increased rates of alcohol or amph etamine use disorder as  well as increased
suicidality.
Increasing age is associated with a decrease in  prevalence as a result of early mortality
and the remission of sy mptoms after age 40 years (i.e., “maturing out”). However, many
individuals continue have presentations that m eet opioid use disorder  criteria for decades.
Risk and Prognostic Factors
Genetic and physiological. The risk for opiate use disorder can be related to individual,
family, peer, and social environmental factors,  but within these domains, genetic factors
play a particularly important role both dire ctly and indirectly. For instance, impulsivity
and novelty seeking are individu al temperaments that relate to the propensity to develop