with gambling disorder may, during a period of gambling, exhibit behavior that resembles
a manic episode, but once the individual is away from the gambling, these manic-like fea-
tures dissipate.
Personality disorders. Problems with gambling  may occur in individuals with antisocial
personality disorder and other personality disorders. If the criteria are met for both disor-
ders, both can be diagnosed. 
Other medical conditions. Some patients taking dopaminergic medications (e.g., for
Parkinson‘s disease) may expe rience urges to gamble. If such symptoms dissipate when
dopaminergic medications are reduced in dosag e or ceased, then a diagnosis of gambling
disorder would not be indicated. 
Comorbidity
Gambling disorder is associated with poor general health. In addition, some specific med-
ical diagnoses, such as tachycardia and an gina, are more common among individuals with
gambling disorder than in the general popula tion, even when other substance use disor-
ders, including tobacco use disorder, are cont rolled for. Individuals with gambling disor-
der have high rates of comorbidity with ot her mental disorders, such as substance use
disorders, depressive d isorders, anxiety disorders, and personality disorders. In some in-
dividuals, other mental disorders may preced e gambling disorder and be either absent or
present during the manifestat ion of gambling disorder. Gamb ling disorder may also occur
prior to the onset of other ment al disorders, especially anxi ety disorders and substance use
disorders.