684 Personality Disorders
Delirium or major neurocognitive disorder. Personality change is a frequently associated
feature of a delirium or major neurocognitive disorder. A separate diagnosis of personal-
ity change due to another medical condition is not given if the change occurs exclusively
during the course of a delirium. However, the diagnosis of personality change due to an-
other medical condition may be given in additi on to the diagnosis of major neurocognitive
disorder if the personality change is a prom inent part of the clinical presentation.
Another mental disorder due to another medical condition. The diagnosis of person-
ality change due to another medical condition is not given if the disturbance is better ex-
plained by another mental disorder due to another medical condition (e.g., depressive
disorder due to brain tumor).
Substance use disorders. Personality changes may also occur in the context of substance
use disorders, especially if the disorder is long -standing. The clinician should inquire carefully
about the nature and extent of substance use. If th e clinician wishes to indicate an etiological re-
lationship between the personality change and su bstance use, the unspecified category for the
specific substance (e.g., unspecified st imulant-related disorder) can be used.
Other mental disorders. Marked personality changes may also be an associated feature
of other mental disorders (e.g., schizophrenia ; delusional disorder; depressive and bipolar
disorders; other specified and unspecified disruptive behavior, impulse-control, and con-
duct disorders; panic disorder). However, in these disorders, no specific physiological fac-
tor is judged to be et iologically related to the personality change.
Other personality disorders. Personality change due to another medical condition can
be distinguished from a persona lity disorder by the requirement for a clinically significant
change from baseline personality functioning and the presence of a specific etiological
medical condition.