ing procedures for ICD-10-CM, which comb ine the substance-induced disorder and
substance use disorder in to a single code, for ICD-9-CM a se parate diagnostic code is given
for the substance use disorder. For example, in the case of anxiety symptoms occurring dur-
ing withdrawal in a man with a severe lorazepam use disorder, the diagnosis is 292.89 loraz-
epam-induced anxiety disorder, with onset du ring withdrawal. An additional diagnosis of
304.10 severe lorazepam use disorder is also given. When more than one substance is judged
to play a significant role in the development of  anxiety symptoms, each should be listed sep-ICD-10-CM
ICD-9-CMWith use 
disorder, 
mildWith use 
disorder, 
moderate 
or severeWithout 
use 
disorder
Alcohol 291.89 F10.180 F10.280 F10.980
Caffeine 292.89 F15.180 F15.280 F15.980
Cannabis 292.89 F12.180 F12.280 F12.980
Phencyclidine 292.89 F16.180 F16.280 F16.980
Other hallucinogen 292.89 F16.180 F16.280 F16.980
Inhalant 292.89 F18.180 F18.280 F18.980
Opioid 292.89 F11.188 F11.288 F11.988
Sedative, hypnotic, or anxiolytic 292.89 F13.180 F13.280 F13.980
Amphetamine (or other 
stimulant)292.89 F15.180 F15.280 F15.980