682 Personality Disorders
Obsessive-compulsive personality traits in moderation may be espe cially adaptive, par-
ticularly in situations that reward high perfor mance. Only when these traits are inflexible,
maladaptive, and persisting and cause significa nt functional impairment or subjective dis-
tress do they constitute obsessive-compulsive personality disorder.
Personality change due to another medical condition. Obsessive-compulsive person-
ality disorder must be distin guished from personality change due to another medical con-
dition, in which the traits emerge attributable to the effects of another medical condition
on the central nervous system.
Substance use disorders. Obsessive-compulsive personality disorder must also be dis-
tinguished from symptoms that may develop in  association with persistent substance use.
Other Personality Disorders
Personality Change
 Due to Another Medical Condition
Diagnostic Criteria 310.1 (F07.0)
A. A persistent personality disturbance that represents a change from the individual’s pre-
vious characteristic personality pattern.
Note:  In children, the disturbance involves a marked deviation from normal devel-
opment or a significant change in the child’s usual behavior patterns, lasting at least
1 year.
B. There is evidence from the history, physical examination, or laboratory findings that the
disturbance is the direct pathophysiological consequence of another medical condition. 
C. The disturbance is not better explained by another mental disorder (including another
mental disorder due to another medical condition).
D. The disturbance does not occur exclusively during the course of a delirium.
E. The disturbance causes clinically significant distress or impairment in social, occupa-
tional, or other important areas of functioning.
Specify whether:
Labile type:  If the predominant feature is affective lability.
Disinhibited type:  If the predominant feature is poor impulse control as evidenced by