Wearing condoms during vaginal, anal, or oral sex can reduce the risk of contracting syphilis. However, the sore or site of infection must be completely covered by the condom. Always use a condom with new sexual partners, as they may not even know whether they have syphilis — especially if there are no visible sores.  Be aware that you may still contract syphilis if the sore is not completely covered by the condom. It's preferable to use dental dams for oral sex with women, as they usually cover a larger area than condoms that have been cut open. However, if you don't have a dental dam, you can cut open a male condom and use it instead. Latex and polyurethane condoms offer equal protection against STDs and HIV. "Natural" or "lambskin" condoms do not adequately protect against STDs.  Use a new condom for each sex act. Don't reuse condoms, even for different types of penetration (vaginal, anal, oral) in the same sexual interaction.  Use water-based lubricants with latex condoms. Oil-based lubes such as petroleum jelly, mineral oil, or body lotion can weaken the latex and make you more likely to contract an STD. You can't guarantee that casual sexual partners aren't carrying STDs. As such, it's best to abstain from casual sex. If you know for a fact that your partner has syphilis, you should avoid sexual contact with them entirely, even if they are wearing a condom. The safest option is to be in a monogamous, long-term relationship with a partner who has tested negative for syphilis and other STDs. The Centers for Disease Control and Prevention advise against the excessive use of alcohol and drugs. These substances can increase a person's likelihood of engaging in risky sexual behavior, which would place you in the "at risk" category. It is very important that pregnant women receive good prenatal care, which involves tests for syphilis. Healthcare professionals and the USPSTF recommend that all pregnant women get screened because syphilis can pass from a mother to her developing baby, causing serious illness and often death.  Babies who contract syphilis from their mothers are much more likely to be underweight, premature, or even stillborn. Even if the child is born without symptoms, untreated babies can develop serious health issues within a matter of weeks. These issues include deafness, cataracts, seizures, and potentially death. This can be avoided if the mother is tested for syphilis throughout the pregnancy and at the time of delivery. If the test comes back positive, both mother and baby can be treated.
لابد من استخدام الواقي الذكري والحاجز الفموي (dental dam). تجنب الممارسات الجنسية العابرة. تجنب الإفراط في شرب الكحول أو تعاطي المخدرات. لابد من الحصول علي الرعاية الكافية  أثناء الحمل.