Functions as a positive regulator of TNF-induced NF-kappa-B signaling (PubMed:27671354). Regulates angiogenesis and cellular metabolism through interaction with PKM (PubMed:27199445). Oligomer (PubMed:29133832). Dimer (PubMed:29133832). Interacts with PKM; regulates angiogenesis and metabolism (PubMed:27199445). N-glycosylated. Extended N-terminus. Extended N-terminus. Extended N-terminus. Extended N-terminus. Extended N-terminus. Extended N-terminus.