Transcriptional activator (PubMed:28017373, PubMed:28017372, PubMed:28017370). Recognizes variations of the palindromic sequence 5'-ATTCCCNNGGGAATT-3' (By similarity). Forms either a homodimer or a heterodimer with a related family member. Expressed in brain. The disease is caused by variants affecting the gene represented in this entry. Belongs to the COE family.