May be involved in the maintenance of mitochondrial organization and mitochondrial cristae structure. Enriched at the cristae junctions. Ubiquitously expressed. Higher expression is observed in heart and liver. The disease is caused by variants affecting the gene represented in this entry. The pathological events leading to disease involve fragmentation of the mitochondrial network, mitochondrial ultrastructural abnormalities including loss, disorganization and dilatation of cristae, and mitochondrial dysfunction associated with respiratory chain deficiency (PubMed:24934289). The disease is caused by variants affecting the gene represented in this entry. The disease is caused by variants affecting the gene represented in this entry.