Component of the Integrator complex, a complex involved in the transcription of small nuclear RNAs (snRNA) and their 3'-box-dependent processing (PubMed:21078872, PubMed:23097424). Involved in the 3'-end processing of the U7 snRNA, and also the spliceosomal snRNAs U1, U2, U4 and U5 (PubMed:21078872, PubMed:23097424). Essential for development (PubMed:19326441, PubMed:21078872). Required for cell signaling and/or cell proliferation (PubMed:19326441). Belongs to the multiprotein complex Integrator, at least composed of IntS1, IntS2, IntS3, IntS4, omd/IntS5, IntS6, defl/IntS7, IntS8, IntS9, IntS10, IntS11, IntS12, asun/IntS13 and IntS14. Predominantly in the nucleus. Expressed at low levels. First detected after cellularization, in the early epidermal tissues of embryos undergoing gastrulation. At later stages of embryogenesis, strongest expression is in the gut, and there is also expression in the central nervous system and perhaps the peripheral nervous system. The name 'deflated' originates from the 'deflated balloon' appearance of mutant abdomens. Belongs to the Integrator subunit 7 family.