Involved in neuronal differentiation. Homodimer (By similarity). Interacts with AHI1 (PubMed:23658157). Expressed in the brain, including hypothalamus, brainstem, and hippocampus. Expression is high in 1-month-old mouse brain and then declines in mature mouse brains at the age of 3 and 7 months. Belongs to the CEND1 family.