Stimulates vascular endothelial cell proliferation (EC(50)=200 pM) in a similar manner than VR-1 and vammin (PubMed:15992764). This angiogenesis probably occurs through VEGF receptor (KDR/VEGFR-2) signaling. Also induces drastic hypotension which is mediated by nitric oxide (NO) (which is produced by VEGF-activated endothelium NO synthase). Also induces capillary permeability (By similarity). Homodimer; disulfide-linked. Expressed by the venom gland. The new subtype VEGF-F is proposed to group snake venom VEGFs that specifically bind to KDR/VEGFR-2. Belongs to the PDGF/VEGF growth factor family. Snake venom VEGF subfamily.