May play a role in actin cytoskeleton reorganization in different tissues since its activation induces formation of actin stress fibers. It works as a guanine nucleotide exchange factor for Rho family of small GTPases. Links specifically G alpha q/11-coupled receptors to RHOA activation. May be an important regulator of processes involved in axon and dendrite formation. In neurons seems to be an exchange factor primarily for RAC1. Involved in skeletal myogenesis (By similarity). Interacts with activated GNAQ and GNA11. Interacts with RHOA, CDC42 and RAC1. Interacts (via the DH domain) with BVES (via the C-terminus cytoplasmic tail) (By similarity). Highly colocalizes with actin regions. The guanine nucleotide exchange activity is autoinhibited by the PH domain.