The primary product of this enzyme is 4,2',4',6'-tetrahydroxychalcone (also termed naringenin-chalcone or chalcone) which undergoes enzyme-catalyzed or spontaneous isomerization into naringenin. 4-coumaroyl-CoA + 2 H(+) + 3 malonyl-CoA = 2',4,4',6'-tetrahydroxychalcone + 3 CO2 + 4 CoA Optimum pH is 7.0. Optimum temperature is 35 degrees Celsius. Secondary metabolite biosynthesis; flavonoid biosynthesis. Belongs to the thiolase-like superfamily. Chalcone/stilbene synthases family.