Pleiotropic ABC efflux transporter involved in the basal level of azole susceptibility (PubMed:26933209). Confers resistance to fluconazole, itraconazole and voriconazole (PubMed:26933209). ATP + H2O + itraconazole(in) = ADP + H(+) + itraconazole(out) + phosphate ATP + H2O + voriconazole(in) = ADP + H(+) + phosphate + voriconazole(out) ATP + fluconazole(in) + H2O = ADP + fluconazole(out) + H(+) + phosphate Expression is increased in clinical azole-resistant isolates. Exhibits enhanced susceptibility to itraconazole, however voriconazole susceptibility is less affected. Belongs to the ABC transporter superfamily. ABCG family. PDR (TC 3.A.1.205) subfamily.