Probable cation channel with high affinity for sodium. In vitro, has no proton-gated channel activity. Homotrimer or heterotrimer with other ASIC proteins. Expressed in central nervous system. First expressed by 30 hours post-fertilization (hpf) along the tract of the anterior commissure, where it persisted until 48 hpf. Detected at 48 hpf in the preoptic area, ventral thalamus, and ventral midbrain and weakly in the ventral hindbrain. At 72 and 96 hpf, expressed throughout most of the brain except the dorsal forebrain. Expressed in the retinal ganglion cells. Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. ASIC2 subfamily.