Strongly outwardly rectifying, electrogenic H(+)/Cl(-)exchanger which mediates the exchange of chloride ions against protons (By similarity). The CLC channel family contains both chloride channels and proton-coupled anion transporters that exchange chloride or another anion for protons (By similarity). The presence of conserved gating glutamate residues is typical for family members that function as antiporters (By similarity). Monomer and homodimer (By similarity). Forms heterodimers with CLCN4 (By similarity). N-glycosylated. Belongs to the chloride channel (TC 2.A.49) family. ClC-3/CLCN3 subfamily.