Component of the elongator complex which is required for multiple tRNA modifications, including mcm5U (5-methoxycarbonylmethyl uridine), mcm5s2U (5-methoxycarbonylmethyl-2-thiouridine), and ncm5U (5-carbamoylmethyl uridine) (PubMed:29332244). The elongator complex catalyzes formation of carboxymethyluridine in the wobble base at position 34 in tRNAs (PubMed:29332244). tRNA modification; 5-methoxycarbonylmethyl-2-thiouridine-tRNA biosynthesis. Component of the elongator complex. Folds into a two seven-bladed beta-propeller structure which is required for elongator complex assembly. Belongs to the WD repeat ELP2 family. The elongator complex was originally thought to play a role in transcription elongation. However, it is no longer thought to play a direct role in this process and its primary function is thought to be in tRNA modification.