Catalyzes specifically the mono-ADP-ribosylation of GcvH-L (SAV0324). This activity is dependent on prior lipoylation of the target protein. May be involved in the modulation of the response to host-derived oxidative stress. In contrast to other sirtuin classes, lacks protein deacylase activity, being unable to catalyze delipoylation, debiotinylation, deacetylation and desuccinylation of proteins. L-aspartyl-[protein] + NAD(+) = 4-O-(ADP-D-ribosyl)-L-aspartyl-[protein] + nicotinamide Binds 1 zinc ion per subunit. Is inhibited by Tenovin-6 in vitro, but not by nicotinamide. The SirTM-mediated ADP-ribosylation can be specifically reversed by the Macro domain-containing protein encoded by the same operon (SAV0325). Belongs to the sirtuin family. Class M subfamily.