Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. (R)-4'-phosphopantetheine + ATP + H(+) = 3'-dephospho-CoA + diphosphate Cofactor biosynthesis; coenzyme A biosynthesis; CoA from (R)-pantothenate: step 4/5. Homohexamer. All subunits in the hexamer bind substrate. Is in equilibrium between two trimers and a hexamer, and the trimer may be a physiologically important form in T.thermophilus. Belongs to the bacterial CoaD family.