Inhibits estrogen-induced cell proliferation by competing with PLCG for binding to ESR1, blocking the effect of estrogen on PLCG and repressing estrogen-induced proliferation. May play a role in T-cell development and function. Interacts with ESR1. Located at podocyte foot processes. Ubiquitously expressed. Aberrantly expressed in some cancers. Truncated N-terminus. Extended C-terminus.