Essential for heme A and Fe/S protein biosynthesis. Binds 1 [2Fe-2S] cluster. Widely expressed, with highest levels in testis, kidney and brain (at protein level) (PubMed:20547883). Expressed in muscle (at protein level) (PubMed:24281368, PubMed:30010796). Expressed in fibroblasts (at protein level) (PubMed:24281368). The disease is caused by variants affecting the gene represented in this entry. Belongs to the adrenodoxin/putidaredoxin family. Truncated N-terminus.