Ena/VASP proteins are actin-associated proteins involved in a range of processes dependent on cytoskeleton remodeling and cell polarity such as axon guidance and lamellipodial and filopodial dynamics in migrating cells. Evl enhances actin nucleation and polymerization (By similarity). During embryonic and tadpole development, expressed in the cement gland, brain, neural tube, myotome and neural placodes, including the otic, lateral line and olfactory placodes. All isoforms show similar spatial expression patterns. First expressed at stage 18. Expression increases through the early tailbud stage (stage 23) and remains relatively high throughout the remainder of development. All isoforms show similar temporal expression patterns. The EVH2 domain is comprised of 3 regions. Block A is a thymosin-like domain required for G-actin binding. The KLKR motif within this block is essential for the G-actin binding and for actin polymerization. Block B is required for F-actin binding and subcellular location, and Block C for tetramerization. Belongs to the Ena/VASP family.