Alkaline phosphatase that can hydrolyze various phosphate compounds. a phosphate monoester + H2O = an alcohol + phosphate Binds 1 Mg(2+) ion. Binds 2 Zn(2+) ions. Homodimer. Detected in placenta (at protein level). Placental ALP is highly polymorphic, there are at least three common alleles. In most mammals there are four different isozymes: placental (ALPP), germ cell (ALPG), intestinal (ALPI) and tissue non-specific (liver/bone/kidney) (ALPL/TNAP). Belongs to the alkaline phosphatase family. Extended N-terminus. Alkaline phosphatase entry