Sodium/ascorbate cotransporter. Mediates electrogenic uptake of vitamin C, with a stoichiometry of 2 Na(+) for each ascorbate. Inactive transporter. L-ascorbate(out) + 2 Na(+)(out) = L-ascorbate(in) + 2 Na(+)(in) Experimental confirmation may be lacking for some isoforms. Highly expressed in adult small intestine, kidney, thymus, ovary, colon, prostate and liver, and in fetal kidney, liver and thymus. Phosphorylated. Treatment with the protein kinase C stimulator PMA results in a 10-fold decrease in ascorbate accumulation in transfected cells. Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.