Probable transporter which may play a role in macrophage lipid transport and homeostasis. Widely expressed with higher expression in liver. Expressed in fetal kidney, lung and liver. Up-regulated during monocyte differentiation into macrophages (PubMed:10639163). Down-regulated by cholesterol loading of macrophages (PubMed:10639163, PubMed:24028821). Belongs to the ABC transporter superfamily. ABCA family. Database for mutations in ABC proteins