May act as a transcription factor. Plays a role in the innate immunity against intracellular pathogens. Required for resistance to M.tuberculosis and L.monocytogenes. Promotes apoptosis of infected cells. Detected in lung and macrophages. Up-regulated after infection with M.tuberculosis. Defects in Sp110 are a cause of severely impaired resistance to infection by M.tuberculosis. Contaminating sequence. Potential poly-A sequence.