Microtubule-associated protein required for mitotic spindle formation and cell-cycle progression in neural progenitor cells. Uniformly distributed along each microtubule bundle of spindles in addition to centrioles during mitosis, expression promptly diminishes at interphase. The KEN box is required for the association with the APC/C-Cdh1 complex, ubiquitination and degradation. Ubiquitinated by the anaphase promoting complex/cyclosome (APC/C). Belongs to the CKAP2 family.