Involved in amino sugar synthesis (formation of chitin, supplies the amino sugars of asparagine-linked oligosaccharides of glycoproteins). D-fructose 6-phosphate + L-glutamine = D-glucosamine 6-phosphate + L-glutamate Nucleotide-sugar biosynthesis; UDP-N-acetyl-alpha-D-glucosamine biosynthesis; alpha-D-glucosamine 6-phosphate from D-fructose 6-phosphate: step 1/1. The activity of this enzyme increases in presence of mating pheromone (transcriptional regulation). Present with 14300 molecules/cell in log phase SD medium.