Cell surface receptor that modulates signaling cascades and mediates tyrosine phosphorylation of target MAP kinases. Interacts with PTPN6 and PTPN11. Ligand binding leads to internalization. Contains 1 copy of a cytoplasmic motif that is referred to as the immunoreceptor tyrosine-based inhibitor motif (ITIM). This motif is involved in modulation of cellular responses. The phosphorylated ITIM motif can bind the SH2 domain of several SH2-containing phosphatases (By similarity).