Toxin that paralyzes insects. May have a direct effect on the insect central nervous system. Expressed by the venom gland. Comprises exclusively 4 tightly packed alpha helices (no beta strand is present). Arose via modification of ancestral neuropeptide hormones (ion transport peptide/crustacean hyperglycemic hormones (ITP/CHH)). Belongs to the helical arthropod-neuropeptide-derived (HAND) family.