Phosphatase with a broad specificity. Its primary physiological function is to dephosphorylate 3'-phosphoadenosine 5'-phosphate (PAP) and 3'-phosphoadenosine 5'-phosphosulfate (PAPS). Thus, plays a role in mycobacterial sulfur metabolism, since it can serve as a key regulator of the sulfate assimilation pathway by controlling the pools of PAP and PAPS in the cell. To a lesser extent, is also able to hydrolyze inositol 1-phosphate (I-1-P), fructose 1,6-bisphosphate (FBP) (to fructose 6-phosphate (F-6-P)) and AMP in vitro, but this might not be significant in vivo (By similarity). adenosine 3',5'-bisphosphate + H2O = AMP + phosphate beta-D-fructose 1,6-bisphosphate + H2O = beta-D-fructose 6-phosphate + phosphate a myo-inositol phosphate + H2O = myo-inositol + phosphate Sulfur metabolism; sulfate assimilation. Homodimer. Belongs to the inositol monophosphatase superfamily.