Acetylates histones H2A and H3 in vitro. (Microbial infection) Acts as negative regulator of immunity when hijacked and relocated to the nucleus by the effector Avh52 from the pathogen Phytophtora sojae (PubMed:30346270). Acts as a susceptibility factor that is hijacked by Avh52 in order to promote acetylation of histones H2A and H3 during early infection by Phytophtora sojae (PubMed:30346270). These epigenetic modifications may up-regulate the expression of potential plant susceptibility genes, thereby promoting susceptibility to Phytophtora sojae (PubMed:30346270). acetyl-CoA + L-lysyl-[histone] = CoA + H(+) + N(6)-acetyl-L-lysyl-[histone] Interacts with the effector Avh52 from the pathogen Phytophtora sojae. Localizes to the cytoplasm, but is relocated to the nucleus when interacting with the effector Avh52 from the pathogen Phytophtora sojae. Plants silencing TAP1 exhibit decreased susceptibility to the pathogen Phytophtora sojae. Belongs to the acetyltransferase family.