Ligand-activated transcription factor. Activated by high concentrations of 9-cis-retinoic acid and all-trans-retinoic acid, but not by dexamethasone, cortisol or progesterone (in vitro) (By similarity). May be involved in motor neuron development. Binds DNA as a homodimer. Highly expressed in the developing spinal motor neurons. Belongs to the nuclear hormone receptor family. NR2 subfamily.