Probable phosphatase (Probable). Required for cell wall integrity and virulence (PubMed:29233914). Phosphorylated. Decreases virulence in mouse intranasal and intravenous model for infection (PubMed:29233914). Sensitive to: high temperature; sodium dodecyl sulfate (cell wall stress inducer); Congo Red (cell wall stress inducer); dithiothreitol; Calcofluor White; salt stress (induced by KCl) (PubMed:29233914). Simultaneous disruption of CRZ1 results in phenotypic enhancement (PubMed:29233914). Belongs to the HAD-like hydrolase superfamily.