The amidated peptide is bactericidal on human pathogens like S.aureus or E.coli, as well as on the fish pathogen A.salmonicida (PubMed:29108968). May also be active against a variety of fungi (By similarity). It can kill bacteria in less than 30 minutes (S.aureus) and 120 minutes (V.vulnificus) (PubMed:29108968). It induces hemolysis of erythrocytes from human and fishes (sea bass and lesser-spotted dogfish) (PubMed:29108968). The non-amidated peptide only inhibits growth of human pathogens like S.aureus or E.coli, and the fish pathogen A.salmonicida. Induces hemolysis of erythrocytes from human and fishes (sea bass and lesser-spotted dogfish). Expressed in gill, skin, intestine, spleen, anterior kidney, and blood cells. This peptide exists in N-terminally amidated and non-amidated forms. The amidated form is more active and has a greater alpha-helix content than the non-amidated form. Amidated form. Non-amidated form. Belongs to the pleurocidin family.