Efflux pump; part of the gene cluster that mediates the biosynthesis of the cyclic tetrapeptide apicidin F (APF) (PubMed:25058475). Secondary metabolite biosynthesis. Expression is positively regulated by the apicidin F cluster-specific transcription factor apf2 that binds to the eight-base-pair motif 5'-TGACGTGA-3' called the 'Api-box' that is found in all promoters of the apicidin F cluster except in the promoter region of apf2 itself (PubMed:25058475). Apicidin F, like the other known apicidins, is a cyclic tetrapeptides with anti-malarial properties via histone deacetylase inhibitory activity (PubMed:24195442). Belongs to the major facilitator superfamily. TCR/Tet family.