Widely expressed. Expressed at low basal level in lung, heart, thymus and spleen; at still lower level in liver, ovary, kidney and brain. Expressed at very weak level in testis. Undetectable in embryo. By interferons. Induced both in response to IFN type I (IFN-alpha and -beta) and IFN type II (IFN-gamma). Belongs to the TRAFAC class dynamin-like GTPase superfamily. Very large inducible GTPase (VLIG) family.