Regulates autophagy by playing a role in the reduction of glucose production in an adiponectin- and insulin-dependent manner. The C-terminal 25 kDa form occurs as a monomer. Secreted in primary hepatocyte-conditioned media. Up-regulated in the plasma by adiponectin in healthy fasting female. Proteolytically cleaved in primary hepatocytes into a C-terminal 80 kDa form (By similarity). Proteolytically cleaved into a C-terminal SOGA 25 kDa form that is detected in plasma. Belongs to the SOGA family. Extended N-terminus.