Plays a role in cytoskeletal rearrangements during the late wrapping and/or compaction phases of myelinogenesis as well as in maintenance and stability of myelin sheath in the adult. May play an important role in late-stage oligodendroglia maturation, myelin/Ranvier node formation during CNS development, and in the maintenance and plasticity of related structures in the mature CNS (By similarity). Binds actin. Expressed specifically by the oligodendrocytes. Highest expression seen in the spinal cord followed by brainstem, cerebellum, thalamus, and hypothalamus. In the myelin sheath, found mainly in the abaxon and the lateral few terminal loops. Its apposition to the myelinated axon, through the latter, defines an axonal subregion, termed juxtanode, at the Ranvier node-paranode junction. Undetected at postnatal day 1 (P1) through P7. Expressed weakly at P10, rapidly increases during the period P14 to P21 and reaches adult levels by P28.