A2-type phospholipase, which is probably involved in the degradation of macrophage membrane (PubMed:20103719). Hydrolyzes dipalmitoylphosphatidylcholine (PubMed:20103719). Also shows moderate esterase activity and hydrolyzes the p-nitrophenol-linked aliphatic ester pNP-butyrate (C4) (PubMed:19225166, PubMed:20103719). Does not exhibit cutinase activity (PubMed:19225166). 1,2-dihexadecanoyl-sn-glycero-3-phosphocholine + H2O = 1-hexadecanoyl-sn-glycero-3-phosphocholine + H(+) + hexadecanoate a butanoate ester + H2O = an aliphatic alcohol + butanoate + H(+) Inhibited by high concentrations of paraoxon (PubMed:19225166). Inhibited by tetrahydrolipstatin (THL), a specific lipase inhibitor (PubMed:20103719). Homodimer. Circulating B cells able to spontaneously generate specific antibodies directed against Culp4 are detected during active tuberculosis and in some latent-tuberculosis cases. Belongs to the cutinase family.