Probable guanine nucleotide exchange factor (GEF). May promote the exchange of GDP to GTP, converting inactive GDP-bound small GTPases into their active GTP-bound form (Probable). May play a role in neuritogenesis, as well as in neuronal recovery and/or restructuring in the hippocampus following transient cerebral ischemia. Expressed within the somatodendritic compartment of neurons, is also present on dendritic growth cones, but is not found in astrocytes. By transient cerebral ischemia. Belongs to the DENND11 family.