Transcriptional activator. When phosphorylated, translocated from nucleus to cytoplasm. High nuclear localization after stimulation with growth factors. Expressed in brain in areas of the nucleus accumbens, cingulate cortex, parts of the amygdala and in the hippocampus. Expressed in developing brain in a specific temporal and spatial pattern. Phosphorylation of Ser-184 is be important in regulating the transacriptional activity.