Cation channel that gives rise to very low constitutive currents in the absence of activation. The activated channel exhibits selectivity for sodium and lithium, and is inhibited by amiloride (By similarity). Homotrimer or heterotrimer with other ASIC proteins. Detected in cerebellum, brainstem, kidney, liver, hepatocytes, lung, intestine and embryo. In the cerebellum. restricted to interneurons in the granular layer, specifically in GRM1-expressing unipolar brush cells of the vestibulocerebellum. Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. ASIC5 subfamily.