Collagen VI acts as a cell-binding protein. Trimers composed of three different chains: alpha-1(VI), alpha-2(VI), and alpha-3(VI) or alpha-4(VI) or alpha-5(VI) or alpha-6(VI). Deposed in the extracellular matrix of skeletal muscle. In newborn, it is expressed in lung, heart, kidney, muscle, brain, intestine, skin, femur, sternum and calvaria. In adult, it is widely expressed and is detected in lung, heart, kidney, spleen, muscle, ovary, uterus, brain, skin, liver and sternum. Prolines at the third position of the tripeptide repeating unit (G-X-Y) are hydroxylated in some or all of the chains. Belongs to the type VI collagen family.