Terpene synthase that catalyzes the cyclization of farnesyl diphosphate (FPP) into a mixture of sesquiterpenes with gamma-muurolene as the most abundant compound and (-)-beta-caryophyllene, alpha-muurolene, and 4 unidentified sesquiterpenes as minor compoundss (PubMed:31839833). TPS1 shows also monoterpene synthase activity and can also use geranyl diphosphate (GPP) as a substrate to convert it into a mixture of cyclic and acyclic monoterpenes, including myrcene and linalool (PubMed:31839833). P.polycephalum has a unique biology and these volatile terpenoids could function in internal communication of P.polycephalum, to mark the territory that have been explored, or they may be involved in chemotaxis (Probable). (2E,6E)-farnesyl diphosphate = diphosphate + gamma-muurolene (2E,6E)-farnesyl diphosphate = alpha-muurolene + diphosphate (2E,6E)-farnesyl diphosphate = (-)-(E)-beta-caryophyllene + diphosphate (2E)-geranyl diphosphate = beta-myrcene + diphosphate The 2 conserved active-site motifs D(D/E)XX(D/E) and NSE are required for coordinating the divalent metal ions that stabilize the PPi moiety of the substrate. The C-terminal WxxxxxRY motif is frequently found in terpene synthases and is important to guide product formation. Belongs to the terpene synthase family.