Critical component of the oxidative stress-induced survival signaling. Activates src family kinases and acts as a scaffolding protein enabling src family kinases to phosphorylate and activate PI3-kinase. Binds RNA and promotes the secretion of IGF-II. May participate in mRNA transport in the cytoplasm (By similarity). Interacts with PURA (By similarity). Interacts with YES1, SRC, FYN. Upon tyrosine phosphorylation, interacts with PIK3R1 (By similarity). Translocates to plasma membrane upon ultraviolet exposure. Arg-978 is dimethylated, probably to asymmetric dimethylarginine. Phosphorylated on tyrosine by src family kinases upon ultraviolet exposure. Belongs to the constitutive coactivator of PPAR-gamma family.