Has vasoactive intestinal peptide(VIP)/secretin-like biological activity. Interacts with rat and human VIP receptors 1 (VIPR1) and 2 (VIPR2), with the highest affinity for the human VIPR2. Induces hypotension that is mediated by relaxation of cardiac smooth muscle. This vasodilation may not be transduced by VIP or PACAP receptors. Expressed by the venom gland. Not expressed in the pancreas, liver, stomach, small intestine, lung, heart, kidney, spleen, ovary, and brain. An amidated Pro-81 is described (PubMed:6439576, PubMed:3569266). Such an amidation is however not compatible with the sequence displayed (PubMed:9545315 and PubMed:10880980). Indeed cDNAs do not encode a Gly that could serve as substrate for peptide alpha-amidation. Belongs to the glucagon family. A longer peptide than exendin-2 has been described in the venom (PubMed:10880980). It has been indicated here as exendin-2-long.