Required for chromosome stability and methionine prototrophy. It is involved in chromosomal segregation. Binds to a highly conserved DNA sequence (5'-RTCACRTG-3'), called CDEI, found in centromeres and in several promoters. DNA-binding activity is enhanced by MET28. Required as an auxiliary factor for transcriptional activation of sulfur metabolism together with MET4 and MET28. Binds DNA as a dimer. Associates with MET4 to form a heteromeric complex which also includes MET28. Present with 6890 molecules/cell in log phase SD medium.