Acts as a cell growth regulator. Also has a crucial role in controlling organ rotation by regulating membrane-localized Notch receptor endocytosis and subsequent degradation. Regulation of organ rotation is not by induction of autophagy. Expressed throughout development, levels increasing from embryo to pupa, then decreasing in adults with higher levels in adult males than females. Homozygous larval lethal. Adult viable flies exhibit genitalia-specific organ rotation phenotypes.