Acts as a regulator of adipogenesis. Involved in the regulation of the feeding behavior. Interacts with TRIO. Interacts with GPS2. Interacts with CCDC85B. Interacts with HMMR. Located just near the plasma membrane in close association with filamentous actin. Widely expressed (PubMed:18162531). Expressed in the arcuate and ventromedial nuclei within the hypothalamus and in the ependyma and the circumventricular organs (at protein level) (PubMed:18162531). Deficient mice display hyperphagia, severe obesity, gigantism, insulin resistance and elevated serum leptin levels potentially linked to defects in primary cilia (PubMed:18162531, PubMed:24633808).