May be involved in salt stress-induced vesicle-to-vacuole trafficking pathway. Through its interaction with ATG8F, may enable delivery of the vesicle bodies to the vacuole by an autophagic pathway (Probable). Plays a role in seed germination in response to exogenous abscisic acid (ABA) treatment (PubMed:22253227). Interacts with ATG8F. Under favorable growth conditions, partially associated with the endoplasmic reticulum (ER) membrane network. Upon exposure to carbon starvation, mainly associated with newly identified spherical compartments that dynamically move along the ER network and reach the lytic vacuole. Plants silencing ATI1 and ATI2 display decreased ability of seed germination in presence of exogenous abscisic acid (ABA). The predicted gene At4g00350 has been split into 2 genes: At4g00350 and At4g00355. The predicted gene At4g00350 has been split into 2 genes: At4g00350 and At4g00355. The predicted gene At4g00350 has been split into 2 genes: At4g00350 and At4g00355.