Hexoaminidase complex may contribute to amoebic pathogenicity and may be involved in the destruction of extracellular matrix components. Hydrolysis of terminal non-reducing N-acetyl-D-hexosamine residues in N-acetyl-beta-D-hexosaminides. Heterodimer of an alpha and a beta subunit. Glycosylated. Belongs to the glycosyl hydrolase 20 family.