This is a copper-containing oxidase that functions in the formation of pigments such as melanins and other polyphenolic compounds. Catalyzes the rate-limiting conversions of tyrosine to DOPA, DOPA to DOPA-quinone and possibly 5,6 dihydroxyindole to indole-5'6 quinone. Binds to the surface of hemocytes and is involved in hemocyte melanization. 2 L-dopa + O2 = 2 H2O + 2 L-dopaquinone L-tyrosine + O2 = H2O + L-dopaquinone Binds 2 copper ions per subunit. Activated by immulectin and lipopolysaccharide. Heterodimer. Forms a complex with an interleukin 1-like protein as a consequence of a host defense response. Synthesized by oenocytoids, a type of hemocyte, and released into the hemolymph plasma. The N-terminus is blocked. Belongs to the tyrosinase family.