Involved in the cytoskeletal anchoring of DLG4 in excitatory synapses. Interacts with DLG4 and TUBB1. Interacts strongly with the PDZ3 domain of members of the DLG4 family. Associates with microtubules. Colocalizes with DLG4 in asymmetric synapses. Expressed in striatum, cortex, midbrain, Purkinje cells of the cerebellum, pyramidal neurons of the hippocampus and neuropil. Expressed in heart, brain, lung, liver, kidney and testis. Belongs to the CRIPT family.