Glucosyltransferase that transfers glucose to the 4-OH-Phegly(4) residue of vancomycin aglycone (AGV) to produce devancoaminyl-vancomycin (DVV) in the biosynthesis of glycopeptide antibiotic chloroeremomycin, a member of the vancomycin group of antibiotics. UDP-alpha-D-glucose + vancomycin aglycone = devancoaminyl-vancomycin + UDP kcat is 33 min(-1). Antibiotic biosynthesis; vancomycin biosynthesis. In A.orientalis different glycosyltransferases are involved in biosynthesis of the vancomycin group of antibiotics. GtfA (AC P96558), GtfB and GtfC (AC P96560) are involved in biosynthesis of antibiotic chloroeremomycin, while GtfD (AC Q9AFC7) and GtfE (AC G4V4R9) are involved in biosynthesis of vancomycin. Belongs to the glycosyltransferase 28 family.