Part of the accessory SecA2/SecY2 system specifically required for export of possible cell wall proteins. The central subunit of a protein translocation channel. Component of the accessory SecA2/SecY2 protein translocase complex required to export cell wall proteins. May form heterotrimers with SecE and SecG subunits. Deletion of 15 genes (from psrP, SP_1772 to SP_1756, includes the accessory Sec export proteins SecA2 and SecY2) and infection of female BALB/cJ mice, shows the psrP-secY2A2 region is required for lung infection and for infection to progress to blood. Mice infected intraperitoneally showed wild-type infection. Decreased adherence to lung but not pharynx or brain cells. The psrP-secY2A2 region deletion has no effect on bacterial growth rate, capsule levels, autolysis, or transformation (PubMed:18507531). In vitro significantly decreased biofilm formation is seen; the large deletion mutant (SP_1772 to SP_1756) is no more affected than the single psrP deletion (PubMed:20714350). Encoded in RD10, a pathogenicity island with an atypical GC content that is associated with invasive pneumococcal disease. Pathogenicity islands account for greater than half the genomic diversity observed between isolates (PubMed:11463916, PubMed:16861665). The main function of this island seems to be correct synthesis and export of pneumococcal serine-rich repeat protein PsrP (PubMed:18507531, PubMed:20714350). Belongs to the SecY/SEC61-alpha family. SecY2 subfamily.