Transcription factor involved in regulation of the aflatoxin biosynthesis gene cluster (PubMed:8250554, PubMed:15006741, PubMed:7793958, PubMed:11913765, PubMed:12655397, PubMed:15054098, PubMed:23605486, PubMed:23342682). Binds with its co-regulator aflS to AFLR1 elements (5'-TCGSWNNSCGR-3') present in the promoters of the aflatoxin cluster genes (PubMed:10216264, PubMed:15746358). The ratio of the expression data between aflS:aflR plays a crucial role in the regulation of aflatoxins production (PubMed:23605486). A high ratio, produced at a range between 17 and 30 degrees Celsius, corresponds with the production profile of aflatoxin G1 biosynthesis (PubMed:23605486). A low ratio, produced over 30 degrees Celsius, is related to aflatoxin B1 biosynthesis (PubMed:23605486). Interacts with its co-regulator aflS (PubMed:12655397, PubMed:15054098, PubMed:23342682). Expression is positively regulated by the developmental and secondary metabolism regulator veA (PubMed:15294809). Expression is repressed during Streptomyces-Aspergillus interactions (PubMed:25741015). Expression is also repressed by curcumin (PubMed:23113196).