Binds cadmium and mediates lower sensitivity to stress requiring glutathione (GSH) for tolerance (e.g. cadmium, selenate, and hydrogen peroxide excess). Probably helps to detoxify cadmium potentially through direct binding (PubMed:18354042, PubMed:19710230). Binds selenium, cadmium, zinc and nickel in vitro (PubMed:25274629). Interacts with GRXS14 and GRXS16 (PubMed:30824043). Interacts with DALL3 (PubMed:31928671). Expressed in seedlings, roots, leaves, stems and flowers. Induced by cadmium (at protein level) (PubMed:16502469, PubMed:18354042, PubMed:19710230). Induced by selenium (selenate), copper and hydrogen peroxide H(2)O(2) (at protein level) (PubMed:16502469, PubMed:18354042, PubMed:19710230). The induction in response to sulfur starvation is repressed by glutathione (GSH) (at protein level) (PubMed:19710230). Belongs to the selenium-binding protein family.