Preferentially cleaves peptide bonds on the carboxyl-terminal side of glutamate. Preferential cleavage: -Glu-|-Xaa- >> -Asp-|-Xaa-. Preference for Pro or Leu at P2 and Phe at P3. Cleavage of -Glu-|-Asp- and -Glu-|-Pro- bonds is slow. Monomer. Belongs to the peptidase S1 family.