Involved in the targeting and/or fusion of transport vesicles to their target membrane. Acts in neuronal exocytosis of synaptic transmission. Likely to have a role in cholinergic transmisson. Required for viability, coordinated movement and M3 pharynx motor neuron function. Part of the SNARE core complex containing ric-4/SNAP25, snb-1/VAMP2 and unc-64/STX1A. This complex binds to cpx-1/CPLX1 (By similarity). Observed in discrete synaptic vesicle puncta along the ventral cord. Functional unc-104, a kinesin-like protein, is required for localization. The two pools of synaptobrevin are recycled by clatherin- and dynamin- dependent endocytosis. AP180-like adapter protein, unc-11, is thought to act as a molecular chaperone. Expressed in the nervous system notably the nerve ring, ventral cord and dorsal cord. Worms exhibit arrested development after embryogenesis. Viable mutants appear lethargic with sporadic jerky movements and absent M3 pharynx motorneuron activity. All mutants are resistant to the acetylcholinesterase inhibitor aldicarb indicating impaired cholinergic transmission. Belongs to the synaptobrevin family.