Protect the extracellular space from toxic effect of reactive oxygen intermediates by converting superoxide radicals into hydrogen peroxide and oxygen. May act in the parasite defense by neutralizing superoxide generated by activated leukocytes, thus acting as both an antioxidant and an anti-inflammatory factor. 2 H(+) + 2 superoxide = H2O2 + O2 Binds 1 copper ion per subunit. Binds 1 zinc ion per subunit. Homodimer. Belongs to the Cu-Zn superoxide dismutase family.