Zinc metalloproteinase-disintegrin VMP-II: inhibits ADP-induced platelet aggregation (probably by binding integrin alpha-IIb/beta-3 (ITGA2B/ITGB3)) and degrades fibrinogen. Recombinant disintegrin r-Cam-dis (413-488): this recombinant protein inhibits platelet adhesion to fibrinogen (IC(50) is 1 nM), inhibits collagen- (IC(50) is 18 nM) and ADP-induced (IC(50) is 6 nM) platelet aggregation, and also inhibits platelet function on clot retraction. May act by binding integrin alpha-IIb/beta-3 (ITGA2B/ITGB3). Binds 1 zinc ion per subunit. Homodimer; disulfide-linked (disintegrin). Expressed by the venom gland. The disintegrin domain belongs to the long disintegrin subfamily. Belongs to the venom metalloproteinase (M12B) family. P-II subfamily. P-IIb sub-subfamily.