Involved in protein transport. Non-ribosomal factor required for efficient nuclear export of the ribosomal 40S subunit. Component of the GSE complex, a GTPase complex required for intracellular sorting of GAP1 out of the endosome. Associates with the pre-40S ribosomal subunit. Component of the GSE complex composed of GTR1, GTR2, SLM4, MEH1 and LTV1. Interacts directly with GTR1. Interacts with CRM1. Shuttles between the nucleus and the cytoplasm. Phosphorylated, leading to its dissociation from the 40S pre-40S ribosome. Present with 589 molecules/cell in log phase SD medium. Belongs to the LTV1 family.