Required for ciliogenesis and for structural integrity at the ciliary tip. Interacts with CCP110 and CEP97. Interacts with ARMC9, TOGARAM1, CCDC66 and CSPP1. In interphase non-ciliated cells, localizes to the distal ends of both the mother and daughter centrioles. In ciliated cells, present at the distal end of the daughter centriole, but not on the mother centriole, and at the tip of primary cilium. Localization at the ciliary tip is also observed in motile cilia. Throughout S phase, associated with both mother and daughter centrioles in each centrosome. During metaphase and telophase, present at both spindle poles. Expressed predominantly in the brain. Also detected, although at much lower levels, in the heart and the liver. Within the brain, expressed in the cerebral cortex, hippocampus, cerebellum and brainstem. Truncated N-terminus.