May play a role in the maintenance of pluripotency. Down-regulated during differentiation. H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate Detectable in the epiblast of oocytes and throughout early mouse embryo development. In adult, expression is localized in gonadal germ cells. Belongs to the protein-tyrosine phosphatase family. Receptor class 3 subfamily.