Component of the nuclear pore complex (NPC), which plays a key role in de novo assembly and insertion of NPC in the nuclear envelope. Required for NPC and nuclear envelope assembly, possibly by forming a link between the nuclear envelope membrane and soluble nucleoporins, thereby anchoring the NPC in the membrane (By similarity). Interacts with the NUP35/NUP53. Central core structure of the nuclear pore complex. Phosphorylated. Belongs to the NDC1 family.