Seed storage protein. Homohexamer (By similarity). Each subunit is composed of an acidic and a basic chain derived from a single precursor and linked by a disulfide bond (PubMed:10606554). Expressed in seeds (at protein level) (PubMed:10606554, PubMed:17517107). Expressed in seeds (PubMed:17556061). Expressed during seed maturation. Expressed in the maturing seeds 24 days after flowering. Causes an allergic reaction in human. Binds to IgE of patients allergic to sesame seeds (PubMed:17517107, PubMed:17556061). Recombinant protein binds to IgE in 58% of the 19 patients tested (PubMed:17517107). Recombinant protein binds strongly to IgE in 54% of the 24 patients tested (PubMed:17556061). Recombinant protein is able to activate basophils previously passively sensitized with sesame-allergic sera in 7 out of 11 patients (PubMed:17517107). Belongs to the 11S seed storage protein (globulins) family.