Complex that is thought to mediate chromatin assembly in DNA replication and DNA repair. Assembles histone octamers onto replicating DNA in vitro. CAF-1 performs the first step of the nucleosome assembly process, bringing newly synthesized histones H3 and H4 to replicating DNA; histones H2A/H2B can bind to this chromatin precursor subsequent to DNA replication to complete the histone octamer. Subunit of the CAF-1 complex that contains RBBP4, CHAF1B and CHAF1A. Interacts with CHAF1B, PCNA and RBBP4 (PubMed:17065558). DNA replication foci. Contains one Pro-Xaa-Val-Xaa-Leu (PxVxL) motif, which is required for interaction with chromoshadow domains. Cells lacking CHAF1A show delayed S-phase progression with retarded DNA synthesis and defects in a rapid nucleosome formation of newly replicated DNA. Belongs to the CHAF1A family. Truncated N-terminus.