Component of the sarcomere that tethers together nebulin (skeletal muscle) and nebulette (cardiac muscle) to alpha-actinin, at the Z lines. Interacts with TTN/titin, NEB, NEBL, ACTN2 and CARP. Bound to sarcomere both at the Z-line periphery and in the central I-band region. Expressed in adult skeletal muscle and fetal heart. The disease is caused by variants affecting the gene represented in this entry. The disease is caused by variants affecting the gene represented in this entry. The disease is caused by variants affecting the gene represented in this entry. The disease is caused by variants affecting the gene represented in this entry. Belongs to the myotilin/palladin family. Probable cloning artifact. Extended N-terminus.