Insulin-regulated facilitative hexose transporter that mediates the transport of glucose and fructose (PubMed:10821868, PubMed:10860996, PubMed:23396969). Also able to mediate the transport of dehydroascorbate (PubMed:23396969). D-glucose(out) = D-glucose(in) D-fructose(out) = D-fructose(in) L-dehydroascorbate(out) = L-dehydroascorbate(in) Inhibited by cytochalasin B. Interacts with AP2B1 (PubMed:16723738). Also able to mediate the transport of dehydroascorbate (PubMed:23396969). Principally intracellular. May move between intracellular vesicles and the plasma membrane. The dileucine internalization motif is critical for intracellular sequestration. Highest level of expression in placenta and testis. Highly expressed in adult and pubertal testis, but not prepubertal testis. Lower levels of expression in brain, liver, heart, kidney, fat and skeletal muscle. High expression in blastocysts. Inhibited under glucose deprivation. Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. Glucose transporter subfamily.