This recombinant peptide inhibits voltage-gated potassium channels mKv1.3/KCNA3 (IC(50)=1.70 uM), mKv1.1/KCNA1 (10 uM inhibits 40% of currents) and hKv1.2/KCNA2 (10 uM inhibits 42% of currents) (PubMed:21308893). May also increase intracellular calcium release through the activation of nuclear inositol 1,4,5-trisphosphate receptors (ITPR) of cardiomyocytes, thereby causing an increase in the contraction frequency of these cells (By similarity). Expressed by the venom gland. The presence of a 'disulfide through disulfide knot' structurally defines this protein as a knottin. Does not show effect on rNav1.2/SCN2A and mNav1.4/SCN4A. Belongs to the scorpion calcin-like family. KTX subfamily.