Involved in the biosynthesis of germacrene-derived sesquiterpene lactones (PubMed:29086444). Hydroxylates germacrene A acid to 8-beta-hydroxy-germacrene A and 8-alpha-hydroxy-germacrene A acids (PubMed:29086444). Unlike 8-alpha-hydroxy-germacrene A acid with is spontaneously converted into inunolide (12, 8-alpha), 8-beta-hydroxy-germacrene A cannot undergo spontaneous lactonization (PubMed:29086444). germacra-1(10),4,11(13)-trien-12-oate + O2 + reduced [NADPH--hemoprotein reductase] = 8beta-hydroxygermacra-1(10),4,11(13)-trien-12-oate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase] germacra-1(10),4,11(13)-trien-12-oate + O2 + reduced [NADPH--hemoprotein reductase] = 8alpha-hydroxygermacra-1(10),4,11(13)-trien-12-oate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase] Secondary metabolite biosynthesis; terpenoid biosynthesis. Mostly expressed in leaves and flowers, and, to a lower extent, in roots and stems. Induced by short jasmonic acid (MeJA) exposure (48 hours), but repressed after a long exposure (120 hours). Belongs to the cytochrome P450 family.