Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor to catalyze sulfonation of hydroxysteroids and xenobiotics. 3'-phosphoadenylyl sulfate + an alcohol = adenosine 3',5'-bisphosphate + an alkyl sulfate + H(+) There is a marked sex difference (female >> male) in the cytosolic level of this protein. Not age-specific. Induced by estrogens and suppressed by androgens (By similarity). The expression is under the influence of pituitary growth hormone and thyroid hormone. Synthesis influenced by aging. Belongs to the sulfotransferase 1 family.