May be involved in pre-mRNA splicing process (PubMed:12163015, PubMed:2044955). Involved in embryonic neurogenesis and cell rearrangement during Malpighian tubule morphogenesis (PubMed:2044955, PubMed:10502111). Colocalizes with a complex containing snRNP proteins. Concentrated in nuclear speckles. Transcribed in all cells during embryonic development. Is expressed throughout embryonic, larval, pupal and adult stages at relatively constant levels. Causes defects in the proliferation of brain neuroblasts and results in the absence of identified neuronal lineages in the central and peripheral nervous systems (PubMed:2044955). During embryonic Malpighian morphogenesis, most of the cells of the Malpighian tubules fail to undergo rearrangement to form tubes with a two cell circumference. Only cells at the distal end of the tubule rearrange (PubMed:10502111). Belongs to the crooked-neck family.