Snake venom zinc metalloproteinase that inhibits ADP-induced human platelet aggregation with an IC(50) of 120 nM (248 nM for the recombinant protein). May act by binding to the receptor GPIIb/GPIIIa (ITGA2B/ITGB3) on the platelet surface (PubMed:14511668). Degrades the alpha-chain of fibrinogen completely and the beta-chain partially, leaving the gamma chain intact (Ref.2). Also inhibits the growth of several cell lines, including human liver cancer cells (Bel7402), human leukemia cells (K562) and human gastric carcinoma cells (BGC823) (PubMed:19732785). Binds 1 zinc ion per subunit. Fibrinogenolytic is completely inhibited by EDTA, but not by PMSF. Monomer. Expressed by the venom gland. The N-terminus is blocked. Does not show hemorrhagic activities after intradermal injection in mice. Does not show pro-coagulant and anti-coagulant activities (Ref.2). The disintegrin domain belongs to the long disintegrin subfamily. Belongs to the venom metalloproteinase (M12B) family. P-II subfamily. P-IIb sub-subfamily. This protein does not undergo proteolytic processing to release the disintegrin domain.