Transcription regulator (PubMed:26571494). Associates with chromatin regions that are associated with ethylene-responses in absence and in presence of ethylene (PubMed:28874528). In the presence of ethylene, promotes histone acetylation in an EIN2- and EIN3-dependent manner, mainly on H3K14 and H3K23, thus regulating positively ethylene-responsive genes (PubMed:27694846, PubMed:28874528). Interacts with RBL (PubMed:30338215). Interacts with the Agrobacterium tumefaciens virulence protein F (VirF) in the nucleus (PubMed:26571494). Binds to EIN2 and EIN3 C-terminal regions in the presence of ethylene to facilitate their association with histone (PubMed:27694846, PubMed:28874528). Binds to histones in chromatin specific regions associated with ethylene regulated loci (PubMed:28874528). Binds to the promoter region of genes influenced by ethylene (PubMed:29298835). Interacts with SRT1 and SRT2; this interaction is enhanced in the presence of ethylene (PubMed:29298835). Observed in nucleoplasmic bodies. Abnormal general transcriptome profiling (PubMed:26571494). Reduced ethylene sensitivity (PubMed:27694846).