Member of the two-component regulatory system RpfG/RpfC, which is involved in the perception and response to the diffusible signaling factor (DSF), which is essential for cell-cell signaling (PubMed:11123673, PubMed:12960398). Detection of DSF leads to the positive regulation of biofilm dispersal and the production of virulence factors (PubMed:12960398). Activated RpfG degrades cyclic di-GMP to GMP, leading to the activation of Clp, a global transcriptional regulator that regulates a large set of genes in DSF pathway. May also directly control genes involved in biofilm dispersal (PubMed:15158198, PubMed:17378922, PubMed:20231439). cyclic di-3',5'-guanylate + 2 H2O = 2 GMP + 2 H(+) Interacts with a subset of GGDEF domain-containing proteins. Localizes predominantly at the cell poles. Contains a C-terminal HD-GYP (modified HD) domain, which is involved in degradation of cyclic di-GMP. The GYP motif is required for interaction with GGDEF domain-containing proteins. Phosphorylated and activated by RpfC. The article describing the function and the phosphodiesterase activity has been retracted due to duplications and irregularities in some figures, but repeated experiments using the original strains support the findings.