Activates host NF-kappa-B and JNK pathways. Induces hyperphosphorylation and redistribution of host bcl-10 from the cytoplasm to the plasma membrane. The inhibitory effect of cellular bcl-10 on NF-kappa-B pathway is then overcome allowing NF-kappa-B activation. E10 does not contain a putative transmembrane and must therefore be targeted to the plasma membrane in a different manner. The two cysteines located on the C-terminal region are essential for the protein localization and constitute a consensus site for geranylgeranylation.