May play a structural role at sites of cell adhesion in maintaining cell shape and motility. In addition to these structural functions, it may also be implicated in signaling events and activation of gene transcription. May be involved in signal transduction from cell adhesion sites to the nucleus allowing successful integration of signals arising from soluble factors and cell-cell adhesion. Also suggested to serve as a scaffold protein upon which distinct protein complexes are assembled in the cytoplasm and in the nucleus (By similarity). Interacts with PDZ domains of SCRIB, with VASP and with ACTN1/alpha-actinin. Found in the nucleus, in the cytoplasm and at cell adhesion sites. Belongs to the zyxin/ajuba family.