Microtubule-associated force-producing protein involved in producing microtubule bundles and able to bind and hydrolyze GTP. Plays a role in the regulation of neuron morphology, axon growth and formation of neuronal growth cones (PubMed:21210813). Plays an important role in vesicular trafficking processes, in particular endocytosis (PubMed:19995918). Involved in cytokinesis (PubMed:21195118). Regulates maturation of apoptotic cell corpse-containing phagosomes by recruiting PIK3C3 to the phagosome membrane (By similarity). GTP + H2O = GDP + H(+) + phosphate Interacts with MYOF (By similarity). Interacts with CTTN and ACTN1 (PubMed:21210813). Interacts with SHANK1, SHANK2 and NOSTRIN (By similarity). Interacts with SH3BP4 (PubMed:16325581). Interacts with SNX9 (By similarity). Interacts with SNX18 (By similarity). Interacts with SNX33 (via SH3 domain) (By similarity). Interacts with MYO1E (via SH3 domain) (PubMed:17257598). Interacts with PSTPIP1 (By similarity). Interacts with CTNND2 (By similarity). May interact with PIK3C3 (By similarity). May be a component of a complex composed of RAB5A (in GDP-bound form), DYN2 and PIK3C3 (By similarity). Interacts with BIN1 (By similarity). Microtubule-associated. Also found in the postsynaptic density of neuronal cells (By similarity). Colocalizes with CTTN at the basis of filopodia in hippocampus neuron growth zones (PubMed:21210813). Co-localizes with PIK3C3 and RAB5A to the nascent phagosome (By similarity). Ubiquitously expressed. Brain expression is restricted to glial cells and fibroblasts. Highest levels in the testis. Phosphorylation at Ser-764 by CDK1 is greatly increased upon mitotic entry. It regulates cytokinesis downstream of calcineurin, and does not affect clathrin-mediated endocytosis. Dephosphorylated by calcineurin/PP2. Phosphorylated on tyrosine residues after activation of SRC (PubMed:19995918). Sequestered to clathrin-coated pits and vesicles at the plasma membrane and the Golgi apparatus. Localized to numerous punctate spots on the plasma membrane. Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.