Receptor for adenosine (By similarity). The activity of this receptor is mediated by G proteins which activate adenylyl cyclase (PubMed:23994616). Interacts (via cytoplasmic C-terminal domain) with USP4; the interaction is direct (By similarity). May interact with DRD4 (By similarity). Interacts with NECAB2 (By similarity). Interacts (via cytoplasmic C-terminal domain) with GAS2L2; interaction enhances receptor-mediated adenylyl cyclase activity (PubMed:23994616). Colocalizes with GAS2L2 at neuronal processes. Expressed in striatal neurons (at protein level). The cytoplasmic C-terminal domain is necessary for targeting the non-ubiquitinated form of this protein to the cell surface. Ubiquitinated. Deubiquitinated by USP4; leading to stabilization and expression at the cell surface (By similarity). Belongs to the G-protein coupled receptor 1 family.