Bacterial hemolysins are exotoxins that attack host cell membranes and cause cell rupture by forming a pore. The Gly-rich region is probably involved in binding calcium, which is required for target cell-binding or cytolytic activity. The three transmembrane domains are believed to be involved in pore formation by the cytotoxin. Fatty acylated by LktC; the toxin only becomes active when modified. Belongs to the RTX prokaryotic toxin (TC 1.C.11) family.