Can hydrolyze NAD but cannot hydrolyze nucleotide di- and triphosphates (PubMed:28898552). Lacks lysopholipase D activity. May play a role in neuronal cell communication (By similarity). Binds 2 Zn(2+) ions per subunit. Expressed abundantly in the brain and kidney, and at lower levels in the liver. N-glycosylated. Belongs to the nucleotide pyrophosphatase/phosphodiesterase family.