Forms a channel through the cell membrane that allows diffusion of small hydrophilic molecules. The channel adopts an open conformation at low or zero membrane potential and a closed conformation at potentials above 30-40 mV. The open state has a weak anion selectivity whereas the closed state is cation-selective (By similarity). Consists mainly of membrane-spanning sided beta-sheets. Has antigenic properties. Elicits a specific immune response in systemic candidiasis human patients undergoing malignant hematological disorders. Belongs to the eukaryotic mitochondrial porin family.