Substrate of protein kinase PTK6 (By similarity). May play a regulatory role in the acute-phase response in systemic inflammation and may modulate STAT3 activity. Interacts with PTK6 and CSF1R. The translocation to the membranes occurs in response to EGF when the protein is overexpressed in fibroblastic cells. Widely expressed. Phosphorylated on tyrosine. Phosphorylated by PTK6 at Tyr-250 modulates PTK6-mediated STAT3 activation.