May be involved in transcription regulation. Widely expressed, with the highest levels in spleen, lung, mesenteric lymph node and kidney. Among splenocytes, predominantly expressed by B-cells (at protein level). Mutant mice are born in expected Mendelian ratios and exhibit no apparent phenotype. Mutant embryonic fibroblasts show an increased oncogenic transformation capacity. Belongs to the class V-like SAM-binding methyltransferase superfamily.