Catalyzes the hydrolysis of fructose 1,6-bisphosphate to fructose 6-phosphate. Can functionally substitute for the FBPase class 3 (Fbp) of B.subtilis. beta-D-fructose 1,6-bisphosphate + H2O = beta-D-fructose 6-phosphate + phosphate Inhibited by phosphoenolpyruvate (PEP). Carbohydrate biosynthesis; gluconeogenesis. Expressed at the same level under glycolytic or gluconeogenic conditions. Disruption of ywjI alone (or fbp alone) does not affect growth on various carbon sources. But the ywjI fbp double mutant is unable to grow with carbon sources demanding FBPase activity, i.e. glycerol, malate, and a mixture of succinate and glutamate. Belongs to the FBPase class 2 family.