Laccase that catalyzes the oxidation of certain aromatic compounds, including L-dopa, to quinones, which then polymerize to melanin (PubMed:1100669, PubMed:6807845, PubMed:6804444, PubMed:8760791). Able to oxidize a wide variety of aromatic diphenol and diamino groups in the ortho, meta, and para positions but not monophenolic groups such as in phenol, tyramine, or tyrosine (PubMed:8300520). Plays an important role in virulence (PubMed:8760791). Plays a role in dissemination to extrapulmonary sites but is not involved in pulmonary growth or in elicitation of cellular immune responses in the lung (PubMed:14977977). 4 hydroquinone + O2 = 4 benzosemiquinone + 2 H2O Binds 4 Cu cations per monomer. Expressed during infection of host (PubMed:8760791). Expression is repressed by glucose (PubMed:8300520). Decreases virulence in mice (PubMed:8760791, PubMed:14977977). Belongs to the multicopper oxidase family.