May be a positive catalyzer of strictosidine production by assisting secologanin biosynthesis, thus being involved in monoterpene indole alkaloids accumulation. Binds 2 Zn(2+) ions per subunit. Alkaloid biosynthesis. Homodimer. Promotes strictosidine production by assisting secologanin biosynthesis when expressed in a S.cerevisiae host optimized for the biosynthesis of monoterpene indole alkaloids. Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily.