This is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins that stimulate adenylate cyclase. It has a high affinity for tricyclic psychotropic drugs (PubMed:7680751). Controls pyramidal neurons migration during corticogenesis, through the regulation of CDK5 activity (By similarity). Is an activator of TOR signaling (By similarity). Interacts with MTOR, RPTOR and NF1 (By similarity). Interacts with CDK5 (By similarity). Localized exclusively in the central nervous system, predominantly in the corpus striatum but also in various limbic and cortical regions. Belongs to the G-protein coupled receptor 1 family.