Thyroid receptor interacting proteins (TRIPs) specifically interact with the ligand binding domain of the thyroid receptor (TR) (PubMed:7776974). Requires the presence of thyroid hormone for its interaction (PubMed:7776974). Interacts with NUFIP1 (PubMed:28335020). Interacts (via HIT-type zinc finger) with the RUVBL1/RUVBL2 complex in the presence of ADP (PubMed:28561026). The disease is caused by variants affecting the gene represented in this entry.