Induced by the two-component regulatory system CreC/CreB and by the signal autoinducer AI-2. Disruption of this gene leads to greater resistance to hydroxylamine and hypersensitivity to ofloxacin, 5,7-dichloro-8-hydroxyquinaldine (a lipophilic chelator) and 18-crown-6 ether (an ionophore). Belongs to the CbrA family.