May function as an adapter protein. Required for efficient phagocytosis of apoptotic cells. Modulates cellular glycosphingolipid and cholesterol transport. May play a role in the internalization and endosomal trafficking of various LRP1 ligands, such as PSAP. Increases cellular levels of GTP-bound ARF6 (By similarity). Homodimer. Interacts with GDP-bound ARF6, but not with GTP-bound ARF6. Part of a complex composed of GULP1, ACAP1 and ARF6. Interacts with ACAP1, LRP1, MEGF10 and STAB2 (By similarity). Interacts with clathrin. May associate with the cytoplasmic side of the plasma membrane and early endosomes (By similarity). Detected in synapses. Detected throughout adult and fetal brain. Detected in cerebellum, cortex and hippocampus (at protein level). Belongs to the ced-6 family.