PPIases accelerate the folding of proteins during protein synthesis. [protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0) Expressed at highest levels in heart, lung and testis. Weakly expressed in kidney and lymph node. Little or no expression detected in brain, thymus, spleen and liver. Expression begins at embryonic day 8.5. Glycosylated. Binds calcium.