Transcriptional repressor, which probably repress transcription by binding directly the 5'-CTGTCAA-3' DNA sequence or by interacting with TGF-beta activated SMAD proteins. Probably represses transcription via the recruitment of histone deacetylase proteins (By similarity). Interacts with the transcriptional modulator SMAD3 and the histone deacetylase HDAC1. Excluded from nucleoli. The C-terminal part is phosphorylated in response to EGF signaling by the Ras/MAPK pathway. Belongs to the TALE/TGIF homeobox family.