Catalyzes the transfer of adenosine 5'-monophosphate (AMP) to Tyr residues of target mitochondrial proteins (AMPylation) (PubMed:30270044). Involved in redox homeostasis by regulating the cellular response to oxidative stress (PubMed:30270044). Regulates protein S-glutathionylation levels possibly by AMPylation of deglutathionylation enzymes such as glutaredoxins (PubMed:30270044). ATP + L-tyrosyl-[protein] = diphosphate + O-(5'-adenylyl)-L-tyrosyl-[protein] Induced in absence of non-fermentable carbon sources including glycerol, lactate, and acetate (at protein level) (PubMed:30270044). Expression is regulated by zinc levels (PubMed:17938904). Forms probably one or more intrachain disulfide bridges. Reduced growth and survival in presence of oxygen reactive species. Present with 2430 molecules/cell in log phase SD medium. Belongs to the SELO family.