Probable transcription regulator which binds to DNA, repressing genes involved in longevity and stress, while activating genes involved in reproduction, such as the vitellogenins (PubMed:30956009, PubMed:31675356). Associates with homeobox unc-62 to regulate gene expression, including repression of genes involved in innate immunity (PubMed:30956009, PubMed:31675356). Required for intestinal expression of vitellogenin genes (PubMed:30956009, PubMed:31675356). Negatively modulates longevity, probably independently of effects on vitellogenesis (PubMed:30956009). Involved in lipid homeostasis, contributing to the reallocation of intestinal lipids to the germline and to the formation of the cuticle (PubMed:30956009, PubMed:31675356). Associates with transcriptional regulator pqm-1 at the daf-16 associated element within the promoters of stress-responsive genes to regulate expression (PubMed:30956009). Forms a heterodimer with homeobox unc-62 (PubMed:30956009, PubMed:31675356). Interacts with pqm-1 (PubMed:30956009). Localizes to the nucleus in an unc-62-dependent manner. Expressed in the intestine at the L4 larval stage and persists into adulthood (PubMed:30956009, PubMed:31675356). Expressed in sensory AWC neurons, pharyngeal muscle cells pm6, and intestine, in the adult (PubMed:30956009, PubMed:31675356). RNAi mediated knockdown targeted to the intestine represses expression of vitellogenin genes. Belongs to the TALE/PBX homeobox family.