Catalyzes the dephosphorylation of C5 and C6 carbon sugars in vitro (PubMed:21575135, PubMed:25848029). Catalyzes the dephosphorylation of 3'-AMP and phosphoserine in vitro (PubMed:25848029). sugar phosphate + H2O = sugar + phosphate. H2O + O-phospho-L-serine = L-serine + phosphate H2O + O-phospho-D-serine = D-serine + phosphate Optimum pH is 7 with 4-nitrophenyl phosphate as substrate. Optimum temperature is 65 degrees Celsius with 4-nitrophenyl phosphate as substrate. Transcription is repressed by glucose and by the binding of AraR to the operon promoter. L-arabinose acts as an inducer by inhibiting the binding of AraR to the DNA, thus allowing expression of the gene. Belongs to the HAD-like hydrolase superfamily.