Ligand for members of the frizzled family of seven transmembrane receptors (Probable). Required for normal tooth development (PubMed:29178643). Regulates the expression of genes involved in tooth development (PubMed:29178643). Detected in embryos (at protein level) (PubMed:29178643). First detected during the segmentation period of embryogenesis (PubMed:8330668). Detected in the developing brain and spinal cord (PubMed:8330668). Detected at constant levels in embryonic head throughout embryonic development, from 18 hpf to 5 dpf (PubMed:29178643). Widely expressed in embryos at 56 hpf (PubMed:29178643). Palmitoleoylation is required for efficient binding to frizzled receptors. Depalmitoleoylation leads to Wnt signaling pathway inhibition. Morpholino knockdown of the protein causes arrest of tooth development. Otherwise, mutant embryos appear grossly normal, excepting some cartilage abnormalities. Wnt10a overexpression in embryos results in loss of anterior neural identity, causing a phenotype with small or no eyes. Belongs to the Wnt family.