Can act either as a transcriptional repressor or as a transcriptional activator, depending on the cell context. Acts as a repressor of the Hedgehog signaling pathway. Represses the Hedgehog-dependent expression of Wnt4. Necessary to maintain the differentiated epithelial phenotype in renal cells through the inhibition of SNAI1, which itself induces the epithelial-to-mesenchymal transition. Represses transcriptional activation by CTNNB1 in the Wnt signaling pathway. May act by recruiting the corepressors CTBP1 and HDAC3. May be involved in neuron differentiation. Interacts with CTBP1 and HDAC3. Interacts with CTNNB1 and CTNND1. Interacts with SUFU. Expressed at high levels in kidney, and at lower levels in heart and lung. Expression begins at 9.5 dpc in cranial ganglia, dorsal root ganglia and neural tube. At 10.5 dpc, broadly expressed in the intermediate zone of the hindbrain, spinal cord and dorsal root ganglia. By 12.5 dpc, expression in the spinal cord becomes restricted to a narrow band of cells in the ventricular zone. The C2H2-type zinc finger 1 has a major repressor function and is required for CTNNB1 binding. C-terminus cleavage is induced by interaction with CTNND1 and enhances by Src tyrosine kinase. Belongs to the GLI C2H2-type zinc-finger protein family.