Elongator complex-associated factor that is not a structural subunit but rather transiently contacts the complex. Regulates elongator complex gamma-toxin target (TOT) activity, resulting in G1 block by Kluyveromyces lactis toxin zymocin (pGKL1 killer toxin), probably through regulation of the ELP1/IKI3 subunit phosphorylation state. Required for an early step in synthesis of 5-methoxycarbonylmethyl (mcm5) and 5-carbamoylmethyl (ncm5) groups present on uridines at the wobble position in tRNA. Interacts with the elongator complex. Present with 5260 molecules/cell in log phase SD medium. Belongs to the KTI12 family.