Suppressor of RNA-mediated gene silencing, also known as post-transcriptional gene silencing (PTGS), a mechanism of plant viral defense that limits the accumulation of viral RNAs. The P0 protein suppresses local PTGS using its F-box-like domain to mediate destabilization and degradation of the AGO1 protein, although not via an interaction with host SKP1A. Participates, together with the proteins P1 and P7, in the inhibition of the induction of aphid-induced host phytohormones. This could play a role in the attraction to the infected plants by aphids. The F-box-like domain is required for suppression of host RNA silencing. Belongs to the polerovirus P0 protein family.