Promotes cell adhesion and matrix assembly. Binds to various extracellular matrix proteins. Expressed in brain, stomach, colon, rectum, liver, lung, kidney, adipocytes and testis. Expressed in embryo at 7 dpc onwards. Expressed in rib, sternal cartilage, heart, kidney, leg muscles, intestine and limb at 7 dpc. Expressed in chondrocytes at 14.5 dpc. Expressed in cartilage at 14 dpc. Present in rib cartilage and choroid plexus epithelium at 16.5 dpc (at protein level). Up-regulated in adipose tissue of obese BRS-3-deficient mice. Phosphorylated. Belongs to the CCDC80 family.