Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the sulfate conjugation of drugs, xenobiotic compounds, hormones, and neurotransmitters. May be involved in the activation of carcinogenic hydroxylamines (By similarity). Liver. Male >> Female. Male specific. Maximum at 9 weeks and maintained in 9-month-old rats. Can be detected at low level in females up to 9-weeK-old rats but then decreases to undetectable level. Induced by estrogens and suppressed by androgens. Belongs to the sulfotransferase 1 family.