May act as scaffold protein (By similarity). May play a role in the development of the retina. Has been suggested to play a role in axon guidance. Binds F-actin. Interacts with ABRA (By similarity). In a striped pattern along the myofibril axis in cardiac myocytes. Associated with the cytoskeleton. Isoform 1 is detected in adult retina, where it is highly expressed in the ganglion layer. Detected in rod inner segment. Isoform 2 is highly expressed in adult retina, brain, kidney and heart. Isoform 3 is highly expressed in adult retina, brain, kidney, liver, skeletal muscle, spleen and heart. Detected in embryonic retina, brain, spinal cord, peripheral sensory ganglia and thymus. Isoform 1 is detected at low levels starting from 12 dpc and remains constant until birth. After this levels increase strongly and expression remains high in adults. Isoform 2 and isoform 3 are expressed at a constant high level throughout development. Isoform 1 is not necessary for normal axon guidance.