GTP-binding protein involved in protein trafficking; may modulate vesicle budding and uncoating within the Golgi apparatus. Involved in endoplasmic reticulum dynamics during embryogenesis (PubMed:15716356). Also required for adult germline function (PubMed:15576487). Plays a role in cell shedding during embryogenesis probably by promoting the endocytosis of cell adhesion molecules (PubMed:22801495). During neurogenesis, involved in cell autonomous Q.p neuroblast asymmetric divisions that generate one precursor cell and one apoptotic cell, probably by controlling endocytosis (PubMed:21596567). Plays a role in maintaining mitochondrial morphology (PubMed:25190516). Expressed in hypodermis, intestine, spermatheca, uterus, gonadal sheath, vulva cells, pharynx muscle, body wall muscle, head neurons, ventral nerve cord. First detected in very young embryos with as little as 48-64 cells. Death during embryogenesis (PubMed:15716356). Some muscle differentiation occurs although it is poorly organized and little elongation or morphogenesis is evident (PubMed:15716356). Extra A/PVM neurons are produced from the precursor Q.pp, which is normally fated to die, acquiring the fate of its sister Q.pa (PubMed:21596567). Q.pa and Q.pp have almost similar size caused by a loss of Q.p asymmetric cell division (PubMed:21596567). In oocytes, plasma membrane localization of rme-2 is impaired resulting in the loss of vit-2 uptake which accumulates in the pseudocoelom (PubMed:21596567). RNAi-mediated knockdown results in a hyper-connected mitochondrial network in body wall muscle cells (PubMed:25190516). Belongs to the small GTPase superfamily. Arf family.