DNA damage-responsive protein that may be required for maintaining the rate of spontaneous mutagenesis. Shows low ATP and GTP hydrolysis activity. Dispensable for acquisition of thermotolerance and does not play a significant role in recovery or protection of cells from acute heat shock. Expression is induced by DNA damage, as well as by salt, oxidative, and heat-shock stress. Probably highly glycosylated. Shows a slightly altered sensitivity to killing by 4-nitroquinoline-1-oxide and to heat shock; and a 6- to 14-fold reduction of the spontaneous mutation rate of reversion of a HIS4 mutation. Belongs to the DDR48 family. sequence is a contaminating peptide from a S.cerevisiae glycogen synthase purification.