Synthesizes cyclic GMP (cGMP) from GTP (By similarity). May be involved in sensitivity to quinine by regulating egl-4 activity through the production of cGMP (PubMed:23874221). GTP = 3',5'-cyclic GMP + diphosphate Binds 1 or 2 heme groups per heterodimer. May be regulated by molecular oxygen. Probably not activated by nitric oxide (NO) (By similarity). Heterodimer; with other soluble guanylate cyclases. Expressed in BAG sensory neuron. There are two types of guanylate cyclases: soluble forms and membrane-associated receptor forms. Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.