Major component of the nuclear lamina, a fibrous layer on the nucleoplasmic side of the inner nuclear membrane (PubMed:11071918, PubMed:25057012). Provides a framework for the nuclear envelope and probably also interacts with chromatin (PubMed:11071918, PubMed:25057012). Essential to maintain the shape and integrity of the nucleus, and for DNA replication (PubMed:11071918). Involved in spatial organization of nuclear pore complexes (PubMed:11071918). It is not a target for ced-3 during apoptosis, suggesting that lamin cleavage is not essential for apoptosis in C.elegans (PubMed:12064941). Interacts with LEM domain proteins lem-2 and emr-1 (PubMed:11870211, PubMed:12684533). May interact with unc-84; this interaction may be required to complete the connection between the nuclear lamina and the cytoskeleton (PubMed:25057012). Remains in the nuclear envelope until late anaphase in early embryos. Depends on mel-28 for nuclear envelope localization after mitosis. Ubiquitous. Expressed in all cells, except in cells undergoing spermatogenesis. Expressed throughout the development and in adults. RNAi-mediated knockdown results in the irregular localization of nuclear envelope associated proteins such as unc-84 (PubMed:11870211). RNAi-mediated knockdown results in nuclear migration defects in hyp7 hypodermal precursor cells (PubMed:25057012). It is the only lamin protein in C.elegans. Belongs to the intermediate filament family.