Hydrolyzes nucleotides into nucleosides (By similarity). Snake venom 5'-nucleotidases are widely distributed among venomous snake taxa, but there is a lack of information about their biological activities. They have been shown to inhibit platelet aggregation. This effect may be due to the liberation of inhibitory AMP or adenosine by its action on ADP released upon initiation of aggregation. Venom 5'-nucleotidases are also known to synergistically act in vivo with other toxins like ADPases, phospholipases, and disintegrins to exert a more pronounced anti-coagulant effect. a ribonucleoside 5'-phosphate + H2O = a ribonucleoside + phosphate Expressed by the venom gland. Venom 5'-nucleotidases (or a part thereof) may be released into the venom via exosome-like vesicles. They may be attached via a GPI anchor to the membrane of these vesicles. Soluble forms of 5'-nucleotidase might be released by cleavage of the ectodomain in the exosome-like vesicles or venom gland cells. Belongs to the 5'-nucleotidase family.