Pleiotropic ABC efflux transporter that may be involved in the modulation susceptibility to a wide range of unrelated cytotoxic compounds. Expression is induced upon exposure to amphotericin B and the allylamine terbinafine. This induction requires the presence of MDR2. Belongs to the ABC transporter superfamily. ABCB family. Multidrug resistance exporter (TC 3.A.1.201) subfamily.