Component of the origin recognition complex (ORC) that binds origins of replication (PubMed:11137005). DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far (PubMed:11137005). ORC is required to assemble the pre-replication complex necessary to initiate DNA replication (PubMed:11137005). As part of the ORC complex, might also have a role in mRNA export (Probable). ORC is composed of six subunits. Interacts with Mcm10 (PubMed:12808023). Interacts with CG9890 (PubMed:30713769). Interaction between the TREX-2/AMEX complex and the ORC complex is required for ORC localization to mRNPs, and consequently mRNA export (PubMed:27016737). Centromeres of metaphase and anaphase chromosomes of early syncytial embryos. Later in development, found in pericentric regions of late anaphase and telophase chromosomes. Detected in embryos (at protein level). Cause death late in larval development, with defects in cell-cycle progression and chromosome condensation in mitosis. Belongs to the ORC2 family.