Substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins (By similarity). Probably recognizes and binds to phosphorylated target proteins (By similarity). In the wing and eye, negatively regulates cell growth and proliferation by mediating the degradation of Myc and cyclin E, respectively (PubMed:11565033, PubMed:15182669). Required for endocycles, but not mitosis in follicle cell epithelium (PubMed:15175253). Protein modification; protein ubiquitination. Part of a SCF E3 ubiquitin-protein ligase complex. Interacts with Myc and puf (PubMed:15182669, PubMed:24173801). Interacts with CycE (PubMed:11565033). Expressed in follicle cell epithelium and imaginal disks, particularly in the morphogenetic furrow. RNAi-mediated knockdown in the posterior compartment of the larval wing disk increases cell size in the posterior compartment of the adult wing, resulting in an increase in the size of the posterior compartment as well as an increase in the ratio between the posterior and anterior areas.