Transcription factor that may play a role in neural and some non-neural tissues development, such as retina and lung respectively. Binds to an 11-bp consensus sequence containing the invariant tetranucleotide 5'-ACGC-3' (By similarity). Predominantly localized to the developing eye. Expressed in the eye anlage at stage 18, where expression increases between stages 21 and 26. At stage 26, localizes to the prospective retina. At stage 29/30, expression is strong within the eye vesicle, in the midbrain and in the nephrostomes of the pronephric kidney. After stage 30, expression in the nephrostomes decreases until stage 33/34 where it is largely absent. Expression in the eye decreases after stage 33/34 until stage 38 where only a few cells in the ciliary marginal zone (CMZ) show expression. Expressed zygotically. Expression begins after mid-blastula transition, diminishes during gastrulation and increases again at stage 15, remaining until stage 45.