Alpha-conotoxins act on postsynaptic membranes, they bind to the nicotinic acetylcholine receptors (nAChR) and thus inhibit them. This toxin inhibits muscle nAChRs with moderate potency (IC(50)=11 uM on alpha-1-beta-1-delta-epsilon/CHRNA1-CHRNB1-CHRND-CHRNE (adult), and IC(50)=13 uM on alpha-1-beta-1-gamma-delta/CHRNA1-CHRNB1-CHRNG-CHRND (fetal)). Expressed by the venom duct. The cysteine framework is I (CC-C-C). Alpha3/5 pattern. Is not active on all neuronal nAChR tested (alpha-2-beta-4/CHRNA2-CHRNB4, alpha-4-beta-2/CHRNA4-CHRNB2, alpha-4-beta-4/CHRNA4-CHRNB4, alpha-7/CHRNA7, and alpha-9-alpha-10/CHRNA9-CHRNA10) (IC(50)>10 uM). Belongs to the conotoxin A superfamily.