Acetyltransferase required for the establishment of sister chromatid cohesion. Couples the processes of cohesion and DNA replication to ensure that only sister chromatids become paired together (By similarity). Essential for early development (PubMed:15256591). acetyl-CoA + L-lysyl-[protein] = CoA + H(+) + N(6)-acetyl-L-lysyl-[protein] The N-terminal region seems to be responsible for association with chromosomes, thus excluding any involvement of the Zn finger in this process. Belongs to the acetyltransferase family. ECO subfamily.