Binds with high affinity to muscular (alpha-1/CHRNA1) and neuronal (alpha-7/CHRNA7) nicotinic acetylcholine receptor (nAChR) and inhibits acetylcholine from binding to the receptor, thereby impairing neuromuscular and neuronal transmission (By similarity). Recombinant LNTX1 leads to a functional block of the muscle-type acetylcholine receptors. Has a cytotoxic activity. This neurotoxin is lethal (PubMed:16689684). Monomer. Expressed by the venom gland. LD(50) is 0.41 mg/kg by intravenous injection into mice. LD(50) is 100 ug/kg by intraperitoneal injection into mice. OH-6A and OH-6B are disulfide isomers which arise from cis-trans isomerization of the Cys-47-Cys-51 disulfide bond. They differ in the retention time in reversed-phase column and the conformation. Belongs to the snake three-finger toxin family. Long-chain subfamily. Type II alpha-neurotoxin sub-subfamily.