Catalyzes 16-beta- and 6-alpha-hydroxylations of testosterone. an organic molecule + O2 + reduced [NADPH--hemoprotein reductase] = an alcohol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase] By pregnenolone-alpha-carbonitrile, dexamethasone, phenobarbital, and triacetyloleandomycin. Belongs to the cytochrome P450 family.