Alpha-conotoxins act on postsynaptic membranes, they bind to the nicotinic acetylcholine receptors (nAChR) and thus inhibit them. This toxin inhibits acetylcholine-evoked currents reversibly in oocytes expressing the human alpha-7 nAChR, and blocks nerve-evoked skeletal muscle contractions in isolated mouse neuromuscular preparations, but with a very low affinity. Expressed by the venom duct. The cysteine framework is I (CC-C-C). Alpha4/7 pattern. Monoisotopic mass. Belongs to the conotoxin A superfamily.