Catalyzes the trimethylation of calmodulin (PubMed:24285794). Regulates roots development probably by modulating auxin signaling responses. May be involved in gravitropism. Involved in abscisic acid (ABA)-mediated and abiotic stress responses, including salt (NaCl), cold, drought and heat stresses (PubMed:24285794). [calmodulin]-L-lysine + S-adenosyl-L-methionine = [calmodulin]-N(6)-methyl-L-lysine + H(+) + S-adenosyl-L-homocysteine Monomer. Expressed in discreet spatial and tissue-specific patterns including root tips, leaves-tips, floral buds, stamens, hydathodes, stigma, anther, siliques, apical meristems and germinating seeds (PubMed:24285794, PubMed:24260266). Also observed at high levels in the root stele region (PubMed:24260266). After seed stratification, first observed in the micropylar end, later present in the endosperm region and in the testa, and finally accumulates in the endosperm and emerging radicle. In seedlings, first detected in the root and cotyledon tips, expression level reaches a maximal at the cotyledonary leaf stage and is later confined in the shoot apical meristem. In roots, expressed at the primary root tip, at the basal side of root curvature, and at the lateral root tip (PubMed:24285794). Also observed in very young primordia, floral buds, and stamens (PubMed:24285794, PubMed:24260266). In stamens, mostly present in the anther containing immature pollen and, at low levels, in the filament. In siliques, highly expressed in the abscission zone and, to a lower extent, in developing seeds (PubMed:24285794). Induced by salt (NaCl) stress (PubMed:24285794, PubMed:24260266). Accumulates in response to osmotic stress (e.g. mannitol) and upon biotic stress, e.g. inoculation with the oomycete P.tabacina (PubMed:24260266). Triggered by auxins indole-3-acetic acid (IAA) and 2,4-dichlorophenoxyacetic acid (2,4-D). Repressed by kinetin or abscisic acid (ABA) treatments (PubMed:24285794). Suppressed calmodulin (CaM) methylation, especially in roots. Longer roots with ectopic root hair cells in atrichoblast cell files and the presence of nonhair cells in trichoblast cell files. Increased number of epidermal cells in the root elongation zone. Reduced root growth inhibition mediated by auxins indole-3-acetic acid (IAA) and 2,4-dichlorophenoxyacetic acid (2,4-D). Reduced sensitivity to abscisic acid (ABA)-mediated stress leading to green cotyledons and normal germination in the presence of ABA. Increased tolerance to abiotic stress such as salt (NaCl), cold, drought and heat stresses. Belongs to the class I-like SAM-binding methyltransferase superfamily. CLNMT methyltransferase family.