Guanylate cyclase involved in the production of the second messenger cGMP (PubMed:27062922). Regulates thermotaxis responses in AFD sensory neurons (PubMed:16415369, PubMed:21315599, PubMed:27062922). May regulate AFD neuronal activity such as calcium responses to temperature gradients (PubMed:16415369, PubMed:21315599). Maintains the microvilli receptive ending morphology of the AFD thermosensory neurons by regulating cGMP levels downstream of kcc-3 (PubMed:27062922). cGMP levels antagonize the actin cytoskeleton regulator wsp-1 (PubMed:27062922). GTP = 3',5'-cyclic GMP + diphosphate Inhibited by chloride with an IC(50) of 60 mM. Localizes exclusively to the sensory ending, known as cilium, in AFD neurons. Expressed bilaterally in AFD sensory neurons. The protein kinase domain is predicted to be catalytically inactive. Might be required for the negative regulation of the guanylate cyclase domain (PubMed:27062922). The guanylate cyclase domain is required for thermotaxis responses. Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.