Promotes AKT phosphorylation, suggesting a possible role in the PI3K-AKT signaling pathway. Belongs to the phosphatidylethanolamine-binding protein family. It was previously reported that PEBP4 is a lysosomal protein which is highly expressed in tumor cells, and may promote cellular resistance to TNF-induced apoptosis. However the paper has since been retracted by the journal due to concerns of image manipulation.