Involved in the synthesis of gangliosides GD1c, GT1a, GQ1b, GP1c and GT3 from GD1a, GT1b, GM1b and GD3 respectively. CMP-N-acetyl-beta-neuraminate + ganglioside GT1b (d18:1(4E)) = CMP + ganglioside GQ1b (d18:1(4E)) + H(+) CMP-N-acetyl-beta-neuraminate + ganglioside GD3 (d18:1(4E)) = CMP + ganglioside GT3 (d18:1(4E)) + H(+) CMP-N-acetyl-beta-neuraminate + ganglioside GD1a (d18:1(4E)) = CMP + ganglioside GT1a (d18:1(4E)) + H(+) CMP-N-acetyl-beta-neuraminate + ganglioside GM1b (d18:1(4E)) = CMP + ganglioside GD1c (d18:1(4E)) + H(+) CMP-N-acetyl-beta-neuraminate + ganglioside GQ1c (d18:1(4E)) = CMP + ganglioside GP1c (d18:1(4E)) + H(+) Protein modification; protein glycosylation. Expressed in fetal and adult brain, adult heart and skeletal muscle. Expressed in fetal and adult brain, not detected in adult heart and skeletal muscle. Belongs to the glycosyltransferase 29 family. ST8Sia V