Part of the ABC transporter complex GlcSTUV involved in glucose uptake (Probable). Responsible for energy coupling to the transport system (PubMed:12823973, PubMed:14607117). In vitro, as a free subunit, exhibits a constitutive ATPase activity (PubMed:11807278). ATP + D-glucose(out) + H2O = ADP + D-glucose(in) + H(+) + phosphate Optimum pH is 6.5 for ATPase activity. The complex is composed of two ATP-binding proteins (GlcV), two transmembrane proteins (GlcT and GlcU) and a solute-binding protein (GlcS) (Probable). Forms transient head-to-tail homodimers in the presence of ATP-Mg(2+) (PubMed:14607117). Consists of a typical ABC-ATPase domain, comprising two subdomains, connected by a linker region to a C-terminal domain of unknown function. Belongs to the ABC transporter superfamily.