Calmodulin mediates the control of a large number of enzymes, ion channels and other proteins by Ca(2+). Among the enzymes to be stimulated by the calmodulin-Ca(2+) complex are a number of protein kinases and phosphatases. Associates with the spoke-associated complex containing CFAP61, CFAP91 and CFAP251; the association is calcium sensitive. Trimethylation of Lys-119 observed in other calmodulins is absent here. This protein has four functional calcium-binding sites. This protein is unusual among eukaryotic calmodulins in having an 11-residue extension of its carboxyl end. Belongs to the calmodulin family.