Secreted effector that acts as an elicitor of hypersensitive response (HR) specifically on plants carrying defense protein RGA2/Rpi-blb1 (PubMed:18682852, PubMed:19888819, PubMed:19794118, PubMed:20479869, PubMed:21483488). Enhances P.infestans colonization of plant hosts Nicotiana benthamiana and potato Solanum bulbocastanum leaves (PubMed:28350531, PubMed:30329083). Associates with host legume-type lectin receptor kinases and disrupts attachments between the host plasma membrane and cell wall (PubMed:14999409, PubMed:21483488). Interacts with host defense protein RGA2/Rpi-blb1 (PubMed:19888819, PubMed:22438813). Interacts with host legume-type lectin receptor kinase LECRK19 (PubMed:16361528). Expression is induced during host plant infection. The RxLR-dEER motif acts to carry the protein into the host cell cytoplasm through binding to cell surface phosphatidylinositol-3-phosphate. The RGD RLK-binding motif is required for binding to host legume-type lectin receptor kinases and disruption of the attachments between the host plasma membrane and cell wall. The conserved W motif is found in already well characterized effectors and is essential for triggering RGA2/Rpi-blb1-mediated cell death. Belongs to the RxLR effector family.