May play a role in cell-cell adhesion and epithelium development through its interaction with proteins of the beta-catenin family (By similarity). May play an important role in cortical development, especially in the maintenance of radial glia (PubMed:22056358). May interact with ARVCF, CTNND1, CTNND2 and PKP4. Localizes to the apical junction of radial glia in the wall of lateral ventricles of the developing brain. Colocalizes with TJP1 on the meshwork-like structure of adherens junctions on the lateral ventricles wall. Predominantly expressed on the surface of the lateral ventricular walls of the developing cerebral cortex. Disrupted in the hemorrhagic hydrocephalus (hhy) mutant. The mutant animals shown sucortical heterotopia and non-obstructive hydrocephalus with frequent brain hemorrhage. Belongs to the CCDC85 family.