Rho GTPase-activating protein which may be involved in clathrin-mediated endocytosis. GTPase activators for the Rho-type GTPases act by converting them to an inactive GDP-bound state. Has activity toward CDC42 and RAC1 (By similarity). Interacts with SH3KBP1/CIN85. Widely expressed. Highly expressed in kidney, lung, small intestine and thymus.