Probable transcription activator. Binds the P5 DNA element sequence 5'-GATCTGAGTCTAATTGAGAATTACTGTAC-3'. Actively transported through the nuclear pore complex (NPC). Expressed in rhabdomyosarcoma TE671 cells as well as in several other normal and cancer cells. Homeobox domain 2 confers nuclear targeting. DUX genes are present in 3.3-kilobase elements, a tandem repeat family scattered in the genome found on the short arms of all acrocentric chromosomes as well as on several other chromosomes. Belongs to the paired homeobox family.