Secreted effector that induces necrotic lesions in Nicotiana benthamiana (PubMed:22352720). Interacts with the host receptor-like kinases (RLKs) BAK1/SERK3 and BKK1/SERK4, inhibits their kinase activity and suppresses INF1-induced pathogen-associated molecular pattern (PAMP)-triggered immunity (PTI) in N.benthamiana (PubMed:30584105). Also interacts with the host receptor-like cytoplasmic kinase (RLCK) BIK1 and inhibits its kinase activity, thereby inhibiting PAMP-induced ROS generation (Probable). In PTI, phosphorylation relaying by RLKs and RLCKs is critical for the initiation of downstream signaling (Probable). The C-terminal region from residues 103 to 132 is important for BAK1/SERK3-binding and the host cell death suppression. Belongs to the NIS1 effector family.