Causes resistance to toxic polyamine concentrations (PubMed:15855155). Present in the 5'-UTR of plasma membrane ATPase 1 (PMA1), the ORF spans two upstream activating sequences (UAS) that are important for the expression of PMA1, and the deletion phenoytpe is attributed to down-regulation of PMA1 (PubMed:16374585). Was originally (PubMed:15855155) thought to function in polyamine resistance, hence the name BRP1, but this phenotype was later (PubMed:16374585) attributed to down-regulation of PMA1.