Component of the large ribosomal subunit. The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. Component of the large ribosomal subunit (PubMed:23636399, PubMed:32669547). Interacts with CRY1 (By similarity). Hydroxylated on His-216 by RIOX1. The modification is impaired by hypoxia. This protein can be partially incorporated into E.coli polysomes in vivo, indicating it can replace the endogenous protein. Belongs to the universal ribosomal protein uL2 family.