Probable transcription factor likely to be involved in early steps in the differentiation of amacrine and ganglion cells. Recognizes and binds to the DNA sequence 5'-ATGCAAAT-3'. Isoform 1 does not bind DNA. Expressed only within the CNS, where its expression is restricted to the medical habenulla, to a dispersed population of neurons in the dorsal hypothalamus, and to subsets of ganglion and amacrine cells in the retina. The disease is caused by variants affecting the gene represented in this entry. Major isoform. Belongs to the POU transcription factor family. Class-6 subfamily. Truncated N-terminus. Truncated N-terminus.