Proposed core component of the chromatin remodeling INO80 complex which is involved in transcriptional regulation, DNA replication and probably DNA repair (By similarity). Together with REF6/EIN6, involved in the epigenetic chromatin-dependent regulatory mechanism that monitors the expression of the essential multifunctional plant stress regulator EIN2 via H3K27me3 repressive histone demethylation and histone variant H2A.Z eviction, thus modulating responses to ethylene (ET), especially during embryogenesis (PubMed:31418686). The INO80 complex controls ethylene-induced H2A.Z eviction dynamics (PubMed:31418686). Component of the chromatin remodeling INO80 complex; specifically part of a complex module associated with the helicase ATP-binding and the helicase C-terminal domain of INO80 (PubMed:31418686). Interacts with ARP5 (PubMed:31418686). Expressed ubiquitously in seedlings. Differential expression of several genes (PubMed:31418686). Compromised ethylene-induced H2A.Z eviction dynamics (PubMed:31418686). Plants missing both EEN and REF6/EIN6 (e.g. ref6-1 een-2 and ein6-1 een-1), are insensitive to ethylene (ET) and exhibit reduced levels of EIN2 associated with a shift of the chromatin landscape to a repressive state at its locus (e.g. H3K27me3 and H2A.Z) (PubMed:31418686). Belongs to the IES6 family.