Responsible for synthesis of pseudouridine from uracil-2605 in 23S ribosomal RNA. uridine(2605) in 23S rRNA = pseudouridine(2605) in 23S rRNA Belongs to the pseudouridine synthase RsuA family. In strain 301 it seems to be a pseudogene. It is interrupted by a frameshift in position 119. The sequence has been verified by the authors and is believed to be correct.