Probable transcriptional regulator, which participates in the transcriptional repression of the presenilin protein hop-1 (PubMed:12668626, PubMed:24670762). Might play a role in the oxidative stress response (PubMed:24670762). Expressed in neurons. Up-regulated by oxidative stress. RNAi-mediated knockdown results in reduced survival upon paraquat treatment to induce oxidative stress. Loss of function results in a suppression of sel-12 phenotypes, possibly by up-regulating hop-1 expression.