Dual endothelin-1/angiotensin-2 receptor that is functionally coupled to a calcium-mobilizing transduction system, responding equivalently to both endothelin-1/EDN1 and angiotensin-2 peptides in a highly specific manner (PubMed:15561758, PubMed:9508787). Also binds the signal peptide of VEGFA (By similarity). May play a role in angiogenesis with a significant role in cardiovascular and neural development (By similarity). Prominently expressed in brain and heart tissues. Weakly expressed in aorta, adrenal gland, and lung tissues.