Downstream target for both neurotrophin and ephrin receptors. May play a role in nerve growth factor (NGF)-induced recruitment of rapgef2 to late endosomes and neurite outgrowth. Interacts (via PDZ-binding motif) with pdzrn3b (via PDZ domain 1). Detected in notochord and brain at the 14-somite stage. Expressed in the ventral region of the eye and in spinal motor neurons at 32 hours post-fertilization. Truncated N-terminus.