May be involved in endothelial cell morphology changes during cell spreading. Required for eye pigmentation. In the retinal pigment epithelium, regulates the biogenesis of melanosomes and promotes their association with the apical cell surface by inducing gamma-tubulin redistribution. Interacts with F-actin. Associates with cortical F-actin. At stage 25, expressed throughout the eye field. At stage 40, expression becomes restricted to the retinal pigment epithelium. The ASD1 domain mediates F-actin binding. Belongs to the shroom family.