Induces capillary permeability and angiogenesis through VEGF receptor (KDR/VEGFR-2) signaling. Homodimer; disulfide-linked. Interacts with high affinity with VEGF receptor-2 (KDR), and with a lower affinity with VEGF receptor-1 (FLT1). Does not bind VEGF receptor-3 (FLT4) and neuropilin-1 (NRP1). Expressed by the venom gland. Belongs to the PDGF/VEGF growth factor family. Snake venom VEGF subfamily.