Pleiotropic ABC efflux transporter involved in the basal level of drugs susceptibility, including antibiotics, azole fungicides and plant defense toxins. Expression is strongly increased by imazalil (PubMed:9180695). Expression is also strongly increased in the presence of hygromycin and 4-nitroquinoline oxide (4-NQO) (PubMed:11872487). Curiously, expression is repressed in the presence of camptothecin, imazalil and itraconazole (PubMed:11872487). Belongs to the ABC transporter superfamily. ABCG family. PDR (TC 3.A.1.205) subfamily.