As accessory component of the DNA polymerase epsilon (DNA polymerase II) participates in chromosomal DNA replication. Heterotetramer. Consists of four subunits: POL2, DPB2, DPB3 and DPB4 (By similarity). In eukaryotes there are five DNA polymerases: alpha, beta, gamma, delta, and epsilon which are responsible for different reactions of DNA synthesis.