Possesses a potent antimicrobial activity against Gram-positive bacteria B.megaterium, C.glutamicum and S.aureus and mollicutes A.laidlawii and S.melliferum (PubMed:10880984). Less active against Gram-negative bacteria B.cepacia, P.aeruginosa, S.typhimurium and S.meliloti. Probably acts by disturbing membrane functions with its amphipathic structure (PubMed:10880984). Highest expression in skin and to a lesser extent in brain and intestine. The sequence shown corresponds to the dermatoxin isolated from frog skin. A variant of it is present in frog brain. Belongs to the frog skin active peptide (FSAP) family. Dermatoxin subfamily.