Promotes cell adhesion and matrix assembly (By similarity). May play a role in eye formation. Binds to various extracellular matrix proteins. Isoform 2 is expressed in the lens placode at stage 14. Isoform 1 is expressed in the lens vesicle at stage 17. Isoform 1 and isoform 2 are expressed in the lens, isthmus, cranial neuronal tube, dermatome and vitelin vein at stage 19. Isoform 1 and isoform 2 are expressed in the lens equatorial region during E4.5 to E10. Belongs to the CCDC80 family.