Has ribonuclease activity towards yeast tRNA, polyadenine, polycytosine and polyguanine, but lacks ribonuclease activity against polyuracil. Has antiproliferative activity towards L1210 tumor cell line with an IC(50) of 41 uM. Lacks mitogenic activity towards murine splenocytes and does not inhibit HIV-1 reverse transcriptase. Activated by Mg(2+) and Zn(2+) ions at low concentrations. Inhibited by Ca(2+), Cu(2+), Fe(2+), Mg(2+), Mn(2+) and Zn(2+) at higher concentrations. Optimum pH is 8. Active from pH 3 to 9. Optimum temperature is 50-70 degrees Celsius.