Plays a role in constitutive splicing and can modulate the selection of alternative splice sites. Represses the splicing of MAPT/Tau exon 10 (By similarity). Interacts with KHDRBS3/SLM-2 (PubMed:11118435). Interacts with HABP4. Interacts with NOL3/ARC/NOP30, NSEP1/YB-1/YB1, SAFB/SAFB1, SRSF6/SFRS6, TRA2B/SFRS10 and C1QBP. May also interact with DUSP11/PIR1 (By similarity). Extensively phosphorylated on serine residues in the RS domain. Belongs to the splicing factor SR family.