Functions as an inhibitor of DNA virus-induced activation of AIM2-like receptors (ALR) inflammasome through interaction with AIM2. Interacts with AIM2; disrupts assembly of the ALR inflammasome complex (PubMed:24531343). Interacts with IFI16 (PubMed:24531343). Interacts with NLRP3 (PubMed:24531343). Expressed in monocytic cell lines and primary macrophages but not in B or T cells. Up-regulated in response to IFNB1 or virus infection.