Seems to play a role in p53-mediated apoptosis induction (By similarity). Binds to NR1D2 and relieves it of its inhibitory effect on the transcription of APOC3 without affecting its DNA-binding activity (By similarity). Interacts with MAPK11 and MAPK14 (By similarity). Component of the chromatin-remodeling SRCAP complex composed of at least SRCAP, DMAP1, RUVBL1, RUVBL2, ACTL6A, YEATS4, ACTR6 and ZNHIT1 (By similarity). Interacts with NR1D1 and NR2D2 (By similarity). Interacts (via HIT-type zinc finger) with the RUVBL1/RUVBL2 complex in the presence of ADP (By similarity). Phosphorylated on Thr by MAPK11 or MAPK14. Belongs to the ZNHIT1 family.