Palmitoyltransferase that could catalyze the addition of palmitate onto various protein substrates (By similarity). Palmitoylates HRAS and LCK (By similarity). May also have a palmitoyltransferase activity toward the beta-2 adrenergic receptor/ADRB2 and therefore regulate G protein-coupled receptor signaling (By similarity). hexadecanoyl-CoA + L-cysteinyl-[protein] = CoA + S-hexadecanoyl-L-cysteinyl-[protein] The DHHC domain is required for palmitoyltransferase activity. Belongs to the DHHC palmitoyltransferase family. ERF2/ZDHHC9 subfamily.