May act as a nucleation-promoting factor at the surface of endosomes, where it recruits and activates the Arp2/3 complex to induce actin polymerization, playing a key role in the fission of tubules that serve as transport intermediates during endosome sorting. Interacts (via WHD1 region) with WASHC2C; the interaction is direct (By similarity). Localization to the endosome membrane is mediated via its interaction with WASHC2. WASH genes duplicated to multiple chromosomal ends during primate evolution, with highest copy number reached in humans, whose WASH repertoires probably vary extensively among individuals (PubMed:18159949). It is therefore difficult to determine which gene is functional or not. The gene coding for this protein is located in the pseudoautosomal region 2 (PAR2) of X and Y chromosomes. Belongs to the WASH1 family. The WASH6P N-terminus differs from WASH3P for which it is shown to be required for the WASH complex assembly. Hence is association within the WASH complex is ambiguous. However, WASH6P retains the regions implicated in interaction with WASHC2 and confering in vitro NPF activity.