Required during anaphase to drive sister chromatid separation to actively depolymerize kinetochore microtubules at their kinetochore-associated plus ends, thereby contributing to chromatid mobility through a 'Pac-man' mechanism. Primarily restricted to centromeric regions of chromosomes during both metaphase and anaphase. Not localized on spindle poles throughout mitosis. Concentrated on the plus ends of kinetochore microtubules embedded in the kinetochore. Defects in chromosome segregation, but does not affect the mitotic spindle. Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. MCAK/KIF2 subfamily.