Plays a role in the definition of cell polarity via the planar cell polarity (PCP) cascade. Required for ciliogenesis by controlling the organization of the apical actin cytoskeleton and the positioning of the basal bodies at the apical cell surface, which in turn is essential for the normal orientation of elongating ciliary microtubules. Proposed to function as core component of a functional module called CPLANE (ciliogenesis and planar polarity effectors) involved in recruitment of peripheral IFT-A proteins to basal bodies (PubMed:27158779). Controls the localization of both rhoa and disheveled in multi-ciliated cells. Has an indirect effect on hedgehog signaling. Interacts with fuz and wdpcp; fuz, intu and wdpcp probably form the core CPLANE (ciliogenesis and planar polarity effectors) complex. Enriched at the apical surface in ciliated cells. Localizes to the cell membrane in non-ciliated cells. Expressed in the neural plate during neural tube closure with subsequent strong expression in the ventral neural tube and in facial mesenchyme. Belongs to the inturned family.