Required for precise axonal bifurcation in mushroom body neurons by suppressing ectopic bifurcation and regulating the guidance of sister axons (PubMed:28396149, PubMed:27908785). Acts downstream of the serine/threonine-protein kinase Bsk to modulate the direction of axon projection (PubMed:28396149). May play a role in fatty acid metabolism (PubMed:27908785). Interacts with Disco. Expressed in the developing nervous system (PubMed:12137943). Ubiquitously expressed in the developing brain (PubMed:27908785). Within the mushroom body, a higher level is detected in the core of lobes and peduncle in the late third instar larva (PubMed:12137943). Detected in whole mushroom body neuron structures at 48 hours after puparium formation and during later stages (PubMed:27908785). Highly expressed in the central nervous system (CNS) in both the brain lobes and the ventral cord throughout embryogenesis, from early stages of neurogenesis. Expressed in both neuroblasts and neurons. Expressed at lower level in the visceral mesoderm during stage 12. Expression of DIP2 overlaps with that of Disco in the visceral mesoderm and CNS. Mushroom body lobe defects including ectopic axon bifurcations and/or axon guidance defects (PubMed:27908785). RNAi-mediated knockdown results in an increase in the number of mushroom body lobes as well as ectopic lobes and guidance defects (PubMed:28396149, PubMed:27908785). Belongs to the DIP2 family.