May play a major role in the structural organization and calcification of developing enamel. May play a role in keratin cytoskeleton disassembly by recruiting CSNK1A1 to keratin filaments. Thereby, it may regulate epithelial cell migration. Interacts with CSNK1A1; recruits CSNK1A1 to keratin filaments. Interacts with KRT18 and probably other keratins. Colocalizes with keratin filaments. Expressed in tooth follicle, eye, liver and kidney. Belongs to the FAM83 family. Extended N-terminus.