Involved in catabolic degradation of epoxides. Shows highest activity towards C6 and C7 carbocyclic epoxides. Also active towards linear 1,2-epoxyalkanes. an epoxide + H2O = an ethanediol Homotetramer. Expressed constitutively at a low level. Induced by cyclohexane oxide and (+/-)trans-1,2-dihydroxycyclohexane. Belongs to the AB hydrolase superfamily. Epoxide hydrolase family.