ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein] ATP + L-threonyl-[protein] = ADP + H(+) + O-phospho-L-threonyl-[protein] In the egg, expressed predominantly in the animal hemisphere. This pattern of expression persists throughout the cleavage and blastula stages. At the gastrula stage, expression is restricted to the ectoderm. In later-stage embryos, expressed over the entire embryonic surface including the open neural plate at stage 15 and the neural tube at stage 22. In tadpoles, strongly expressed in the neural tube, motor neurons, brain regions and sensory organs (otic vesicle and eye). Also expressed in the perisomitic mesoderm, brachial arches and embryonic epidermis of tadpoles. Expressed both maternally and zygotically. Expressed throughout development. Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. SNF1 subfamily.