Receptor for angiotensin II, a vasoconstricting peptide (PubMed:8726696). Signals primarily via a non-canonical G-protein- and beta-arrestin independent pathways (By similarity). Cooperates with MTUS1 to inhibit ERK2 activation and cell proliferation (PubMed:15539617). Interacts with MTUS1. Expressed at highest levels in adrenal gland and uterus. Helix VIII may act as a gatekeeper for either suppression or activation of the receptor, depending on post-translational modifications and interactions with various receptor partners. Helix VIII is found in a non-canonical position, stabilizing the active-like state, but at the same time preventing the recruitment of G-proteins or beta-arrestins. Upon switching to a membrane-bound conformation, helix VIII can support the recruitment of G proteins and beta-arrestins. Belongs to the G-protein coupled receptor 1 family.