Key component of the 4EHP-GYF2 complex, a multiprotein complex that acts as a repressor of translation initiation (PubMed:31114929). In the 4EHP-GYF2 complex, promotes translational repression and decay of mRNA targets by recruiting and bridging the association of the 4EHP complex with decapping effector proteins, such as me31B and Patr-1, and the deadenylation CCR4-NOT complex (PubMed:31114929). Involved in regulating starvation-induced, developmental and physiological autophagy, which is critical for eliminating ubiquitinated proteins and dysfunctional organelles in order to maintain tissue homeostasis (PubMed:26086452). Component of the 4EHP-GYF2 complex, composed of at least eIF4EHP and Gyf (PubMed:31114929). Interacts (via N-terminus) with eIF4EHP; interaction is required for eIF4EHP-mediated translational repression and mRNA decay (PubMed:31114929). Interacts (via me31B binding motif) with the decapping activator DDX6/ME31B (via RecA-like domain 2), and also interacts (via GYF domain) with the decapping effector protein Patr-1 (PubMed:31114929, PubMed:31439631). Also interacts with other decapping effector proteins, such as Edc3 and Ge-1 (PubMed:31114929). Interacts with CCR4-NOT deadenylase complex members Not1, Not3, Pop2 and twin, and other components of the deadenylation complexes such as Rga, PAN2 and PAN3 (PubMed:31114929). Larvae and adults display defects in starvation-induced, developmental and physiological autophagy, which result in the accumulation of autophagosomes, autolysosomes, and increased Atg8a expression (PubMed:26086452). Adults display reduced locomotion and decreased life span, likely due to the dysregulation of autophagy which results in the accumulation of ubiquitinated proteins and dysfunctional mitochondria in neuronal and muscle tissues (PubMed:26086452). TORC1 signaling is also inhibited, possibly to compensate for the loss of autophagy (PubMed:26086452). Belongs to the GIGYF family. Truncated N-terminus. Extended N-terminus. Extended N-terminus.