Growth factor for endothelial cells. VEGF-B167 binds heparin and neuropilin-1 whereas the binding to neuropilin-1 of VEGF-B186 is regulated by proteolysis (By similarity). Homodimer; disulfide-linked. Can also form heterodimer with VEGF (By similarity). Secreted but remains associated to cells or to the extracellular matrix unless released by heparin. Additional isoforms seem to exist. VEGF-B186 is O-glycosylated. Belongs to the PDGF/VEGF growth factor family.