Modulates cellular glycosphingolipid and cholesterol transport. May play a role in the internalization of various LRP1 ligands, such as PSAP (By similarity). May function as an adapter protein. Required for efficient phagocytosis of apoptotic cells. Increases cellular levels of GTP-bound ARF6. Homodimer. Interacts with clathrin and MEGF10 (By similarity). Interacts with GDP-bound ARF6, but not with GTP-bound ARF6. Part of a complex composed of GULP1, ACAP1 and ARF6. Interacts with ACAP1, LRP1 and STAB2. May associate with the cytoplasmic side of the plasma membrane and early endosomes. Detected throughout the brain, particularly in Purkinje cells, hippocampal and cortical neurons (at protein level). Belongs to the ced-6 family.