Required for protection of the roots from inhibitory compounds. When expressed in a heterologous system, confers resistance to tetramethylammonium chloride. Expressed in the root epidermis and cortex. Not expressed in hypocotyl. Detected in the elongation zone of young roots, but not in the meristematic region. Aberrant lateral root formation due to hypersensitivity to toxic compounds. Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family.