Global transcriptional regulator of pathogenicity. Regulates many genes during growth in putrescine medium and during infection. Involved in the developmental processes of conidium formation and sexual reproduction and modulates a morphological change that accompanies mycotoxin production. Results in greatly reduced pathogenicity and loss of trichothecene toxin accumulation in infected wheat plants. Exhibits normal vegetative growth but shows defects in asexual and sexual spore development. Belongs to the MIT1/WOR1 family.