Inhibitor of ligand binding to the integrins alpha-IIb/beta-3 (ITGA2B/ITGB3). Competition with fibrinogen for the RGD recognition sites on the alpha-IIb/beta-3 integrin results in the inhibition of platelet aggregation induced by ADP, thrombin, platelet-activating factor and collagen. Monomer. Expressed by the venom gland. This peptide has served as a model to produce eptifibatide (Integrilin), a cyclic heptapeptide available in the market as antiplatelet agent. The disintegrin belongs to the medium disintegrin subfamily. Belongs to the venom metalloproteinase (M12B) family. P-II subfamily. P-IIa sub-subfamily.