Major component of Woronin bodies, fungal-specific organelles that occlude septal pores in order to separate intact from damaged compartments (PubMed:11273682, PubMed:10783241). Hex-1 binds directly or indirectly to the Woronin body tether that in turn is anchored at the rim of the septal pore (PubMed:11273682, PubMed:10783241). Forms oligomers (PubMed:11273682, PubMed:10783241). Self-assembles into hexagonal rods (PubMed:10783241, PubMed:12640443). Localizes at Woronin bodies, fungal-specific organelles that plug the septal pore in case of physical damage. Impairs plugging of septal pores and leads to the loss of cytoplasm in hyphae severed by lightly drawing a scalpel blade. Belongs to the eIF-5A family. Hex1 subfamily.