May be required for replication-independent chromatin assembly (By similarity). May serve as a negative regulator of T-cell receptor (TCR) signaling via inhibition of calcineurin. Component of a complex that includes at least ASF1A, CABIN1, HIRA, histone H3.3 and UBN1 (By similarity). Interacts with MEF2B (By similarity). Interacts with calcineurin. Widely expressed with prominent expression in neurons. Activated through PKC-mediated hyperphosphorylation.