Nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates. Has highest activity toward AMP, and weaker activity toward dAMP, CMP and dCMP. Also displays broad nucleoside diphosphate kinase activity. AMP + ATP = 2 ADP a 2'-deoxyribonucleoside 5'-diphosphate + ATP = a 2'-deoxyribonucleoside 5'-triphosphate + ADP a ribonucleoside 5'-diphosphate + ATP = a ribonucleoside 5'-triphosphate + ADP Interacts with CFAP45 and CFAP52; CFAP45 and AK8 dimerization may create a cavity at the interface of the dimer that can accommodate AMP. Located in the proximal region of respiratory cilia. Expressed in respiratory cells (at protein level). Belongs to the adenylate kinase family.