This enzyme has two NAD(+)-dependent activities: ADH and ACDH. May be a critical enzyme in the fermentative pathway. a primary alcohol + NAD(+) = an aldehyde + H(+) + NADH a secondary alcohol + NAD(+) = a ketone + H(+) + NADH acetaldehyde + CoA + NAD(+) = acetyl-CoA + H(+) + NADH Zinc or iron. Seems to form a rod shaped homomer composed of at least 20 identical subunits. In the N-terminal section; belongs to the aldehyde dehydrogenase family. In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family.