Collagen receptor involved in collagen-induced platelet adhesion and activation (PubMed:16139873, PubMed:24368846). Plays a key role in platelet procoagulant activity and subsequent thrombin and fibrin formation. This procoagulant function may contribute to arterial and venous thrombus formation. The signaling pathway involves the FcR gamma-chain, the Src kinases (likely FYN or LYN) and SYK, the adapter protein LAT and leads to the activation of PLCG2. Associated with Fc receptor gamma chain. The GPVI:FcRgamma complex is associated with the Src kinase family FYN and LYN. Interacts with TRAF4 (By similarity). Interacts with COL1A1, but not with COL4A4 (PubMed:24368846). Megakaryocytes and platelets. Expressed at embryonic day 13.5, 14.5 and 16.5. Expression decreases in intensity at day 18.5 and in 1.5 day-old newborn. Mice deficient in Gp6 show a complete protection against arterial thrombosis and induced pulmonary thromboembolism, without significant prolongation of bleeding time (PubMed:16139873). Mutant mice deficient in Gp6 and P3h2 are born at the expected Mendelian rate and have no visible phenotype (PubMed:24368846).