Phosphatidylinositol 3-kinase homolog that regulates longevity and diapause (PubMed:8700226, PubMed:21750263). Promotes cell survival during embryonic development by recruiting akt-1/2 to the plasma membrane through the production of PtdIns(3,4,5)P3 (PubMed:25383666). Could function in the development or neuroendocrine signaling of the dauer pathway (PubMed:8700226). Mediates susceptibility to enteropathogenic E.coli infection (PubMed:16091039). May negatively regulate AYI interneuron neurite outgrowth (PubMed:22069193). Plays a role in aversive olfactory learning when an odor is associated with food deprivation (PubMed:27383131). Regulates this process by promoting the nuclear relocalization of egl-4 in AWC olfactory neurons after odor conditioning (PubMed:27383131). a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ADP + H(+) Expressed both maternally and zygotically. Belongs to the PI3/PI4-kinase family.