Specific regulator of choline metabolism, which activates transcription of at least 25 genes from 11 promoters in response to choline metabolites (PubMed:24097953). Required for the induction of plcH, encoding the phospholipase C, and pchP, encoding the phosphorylcholine phosphatase, in response to glycine betaine (GB) and dimethylglycine (DMG) (PubMed:19103776). Also controls the expression of gbcAB and dgcAB, which are required for GB and DMG degradation, respectively, in response to both GB and DMG (PubMed:17951379). The GbdR regulon also includes genes encoding sarcosine, glycine and serine catabolic enzymes, the BetX and CbcXWV quaternary amine transport proteins and the acetylcholine esterase gene, choE (PubMed:24097953). Acts by binding directly to the promoter region of the genes (PubMed:24097953). May play an important role during P.aeruginosa interactions with eukaryotes (PubMed:17951379). Mutant is unable to grow on choline, GB and DMG as sole carbon or nitrogen sources (PubMed:17951379). Deletion mutant cannot induce expression of plcH (PubMed:19103776).