Probable ligand for integrin in the brain. This is a non-catalytic metalloprotease-like protein. Detected in testis and barely expressed in heart and muscle. Not detectable in liver. Could not be detected in embryos until neurulation. In developing embryos, the expression is restricted to neural crest derivatives. A conserved motif [AVN[ED]CD] within the disintegrin-like domain could be involved in the binding to the integrin receptor. The precursor is cleaved by a furin endopeptidase.