May have an involvement in muscle development or hypertrophy. (Microbial infection) Interacts (via LIM domain 1) with Chikungunya virus non-structural protein 3 (via C-terminus); this interaction is required for viral RNA replication. Predominantly nuclear in myoblasts but is cytosolic in differentiated myotubes. Isoform 1 is highly expressed in skeletal muscle and to a lesser extent in heart, placenta, ovary, prostate, testis, small intestine, colon and spleen. Expression is barely detectable in brain, lung, liver, kidney, pancreas, thymus and peripheral blood leukocytes. Isoform 2 is expressed in brain, skeletal muscle and to a lesser extent in heart, colon, prostate and small intestine. Isoform 3 is expressed in testis, heart and skeletal muscle. Elevated levels during postnatal muscle growth. The disease is caused by variants affecting distinct genetic loci, including the gene represented in this entry. The disease is caused by variants affecting the gene represented in this entry. The disease is caused by variants affecting the gene represented in this entry. The disease is caused by variants affecting the gene represented in this entry. The disease is caused by variants affecting the gene represented in this entry. The disease is caused by variants affecting the gene represented in this entry. Truncated N-terminus.