Vacuolar transporter that is involved in the transport of excess nickel into the vacuole under iron deficiency, increasing cellular tolerance to nickel under iron deficiency stress response. Tonoplast. By iron deficiency in roots. No visible phenotype under normal growth conditions, but plants have increased sensitivity to nickel when grown in an iron-deficient environment. Plants over-expressing IREG2 show increased tolerance to elevated concentrations of nickel. Belongs to the ferroportin (FP) (TC 2.A.100) family. SLC40A subfamily. Sequencing errors.