Sequence-specific DNA-binding transcriptional regulator. Plays a role as a molecular node in a transcriptional network regulating embryonic development and cell fate decision. Stimulates the expression of upstream key transcriptional activators and repressors of the Wnt/beta-catenin and MAPK/ERK pathways, respectively, that are essential for naive pluripotency and self-renewal maintenance of embryonic stem cells (ESCs). Specifically promotes SPRY1 and RSPO1 transcription activation through recognition and direct binding of a specific DNA sequence in their promoter regions. Also plays a role in induced pluripotent stem cells (iPSCs) reprogramming. Involved in early embryo development. Expressed in embryonic stem cells (ESCs) (at protein level). Mice die before birth and show early postimplantation developmental defect. Display reduced embryonic stem cells (ESCs) proliferation and self-renewal capacity. Show altered transcription of naive pluripotency and self-renewal modulator genes.