Transcription factor that may have a role in kidney cell differentiation (PubMed:24676634). Has a critical role in the development of the urogenital tract, the eyes, and the CNS. Interacts with ELGN3; the interaction targets PAX2 for destruction. Interacts with TLE4. Expressed in primitive cells of the kidney, ureter, eye, ear and central nervous system. Mainly in fetal kidney and juvenile nephrogenic rests. The disease is caused by variants affecting the gene represented in this entry. The disease is caused by variants affecting the gene represented in this entry. Leiden Open Variation Database (LOVD)