Component of the nuclear pore complex, a complex required for the trafficking across the nuclear membrane (PubMed:15086791). Together with Nup54, required for transposable element silencing regulation in ovarian follicle cells (PubMed:33856346). By interacting with the nuclear (Nxf1/Nxt1) and cytosolic (fs(1)Yb) components of the flamenco (flam) transcripts processing pathway, enables export and subsequent piRNA production (PubMed:33856346). Component of the nuclear pore complex (PubMed:15086791). Interacts with Nup54 (PubMed:33856346). Interacts (via C-terminus) with fs(1)Yb; this interaction occurs in a RNA-independent manner (PubMed:33856346). Interacts with sbr/nxf1 (PubMed:33856346). Interacts with Nxt1 (PubMed:33856346). Present also in annulate lamellae pore complexes (ALPCs). Expressed during embryonic development (at protein level). Contains FG repeats. FG repeats are interaction sites for karyopherins (importins, exportins) and form probably an affinity gradient, guiding the transport proteins unidirectionally with their cargo through the NPC. FG repeat regions are highly flexible and lack ordered secondary structure. The overall conservation of FG repeats regarding exact sequence, spacing, and repeat unit length is limited. O-glycosylated; contains O-GlcNAc (PubMed:15086791, PubMed:24706800). O-GlcNAcylation increases with increasing ambient temperature (PubMed:24706800). Belongs to the NUP58 family.