Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Binds to the DNA sequence 5'-AA[AT]TTTTATTAC-3'. Interacts with SIRT2; the interaction is direct. Expressed in the developing limb bud where it is restricted to the mesenchyme along the proximal-distal axis. Also found in developing gut and urogenital tract. In adult tissue, both forms found in kidney but only isoform 1 is expressed in skeletal muscle. Embryonic expression increases from day 9 to day 12 and then declines to day 15. Belongs to the Abd-B homeobox family. Truncated N-terminus. Truncated N-terminus.