Guanylate cyclase involved in the production of the second messenger cGMP (By similarity). Involved in the sensing of K+ gradient by the ASE right (ASER) sensory neuron (PubMed:19523832). GTP = 3',5'-cyclic GMP + diphosphate Expressed predominantly in sensory neurons. Expressed asymmetrically in the right ASE (ASER) neuron and bilaterally in ASI and URX neurons. Expressed in PVT and bilaterally in AIY non-sensory neurons. Expressed in intestine. The protein kinase domain is predicted to be catalytically inactive. Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.