Transcription factor with a key role in the maintenance and self-renewal of embryonic and hematopoietic stem cells. Interacts with POU5F1/OCT4 (By similarity). Interacts with NANOG (PubMed:16840789). Interacts with BEND3 (By similarity). Interacts with NSD2 (via PHD-type zinc fingers 1, 2 and 3) (PubMed:19483677). Expressed in the embryonic heart (at protein level). Sumoylation with both SUMO1 and SUMO2 regulates the stability, subcellular localization, transcriptional activity, and may reduce interaction with POU5F1/OCT4. Belongs to the sal C2H2-type zinc-finger protein family.