DNA repair protein that may operate in a postreplication repair or a cell cycle checkpoint function. May be involved in interstrand DNA cross-link repair and in the maintenance of normal chromosome stability (By similarity). Belongs to the multisubunit FA complex composed of FANCA, FANCB, FANCC, FANCE, FANCF, FANCG, FANCL/PHF9 and FANCM (By similarity). In complex with FANCF, FANCG and FANCL, but not with FANCC, nor FANCE, interacts with HES1; this interaction may be essential for the stability and nuclear localization of FA core complex proteins (By similarity). The complex with FANCC and FANCG may also include EIF2AK2 and HSP70. Interacts with FAAP20; interaction is direct (By similarity). The major form is nuclear. The minor form is cytoplasmic. Mainly expressed in testis and lymphoid tissues like thymus, lymph nodes, and spleen, and at lower levels in kidney and ovary. Phosphorylated primarily on serine residues. Phosphorylation is required for the formation of the nuclear complex (By similarity).