May play a role in the negative regulation of cell cycle progression. The EGFP- and MYC-tagged protein has been shown to be cytoplasmic. Expressed in several embryonic and adult tissues, including adult and fetal brain, liver, spleen and pancreas. Expressed in adult, but not fetal kidney. Expressed in skin and squamous cell carcinoma (SCC) and in several other cancer types. Also detected in lesion actinic keratosis (AK). Belongs to the cytokine receptor-like factor 3 family.