Component of the large ribosomal subunit. The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell (By similarity). Plays an essential role in early embryonic development (PubMed:12006978). May act as a haploinsufficient tumor suppressor (PubMed:15138505). Component of the large ribosomal subunit. Embryos show various defects including an inflated hindbrain ventricle and smaller head and eyes. Mutant adults show an increased incidence of cancer, notably malignant peripheral nerve sheath tumors. Belongs to the universal ribosomal protein uL29 family.