Scorpion venom natriuretic peptide that increases the perfusion pressure, glomerular filtration rate and urinary flow in the isolated perfused rat kidney assay. Induces a decrease of the percentages of renal transport for sodium, potassium and chloride and an increase of the urinary cGMP concentration. Also down-regulates the mRNA expression of natriuretic peptide receptor-A (NPR1) in the kidneys whereas it up-regulates those of NPR-B (NPR2), NPR-C (NPR3) and guanylyl cyclase C (GUCY2C) mRNAs. May exhibit hypotensive and vasodepressor activities. Expressed by the venom gland. Belongs to the natriuretic peptide family.