Stabilizes microtubules and may regulate actin fiber dynamics through the activation of Rho family GTPases. May also function in Wnt signaling by promoting the rapid degradation of CTNNB1. Interacts with APC, CTNNB1, TP53BP2 and possibly with AXIN2 (By similarity). Interacts with MAPRE3, PSRC1 and probably MAPRE1. Associated with actin filaments. Associated with microtubule network. Expressed in brain and other neural tissues. Strongly expressed in fetal brain but expression decreases from P12 onward. Expressed in postmitotic neurons. Mice display abnormal head shape with shortened skull length and no change in the skull height. Brain ventricles of these mice are significantly larger and the thickness of the corpus callosum is significantly reduced. They show increased exploratory activity and have impaired learning memory function. Belongs to the adenomatous polyposis coli (APC) family.