Promotes cell adhesion and matrix assembly. Binds to various extracellular matrix proteins. Expressed in dermal papilla and dermal fibroblasts (at protein level). Expressed in heart, thymus, placenta, pancreas, colon, epithelium, spleen and osteoblasts. Down-regulated in cancer and after osteoblastic differentiation. Up-regulated by dihydrotestosterone (DHT). Phosphorylated. Belongs to the CCDC80 family.