Negative regulator of sphingolipid synthesis. Ubiquitously and homogeneously expressed in the syncytial blastoderm and during the cellularization stage. In stages 11-12, it is expressed in the germ-band layer In later stages (stage 14), it is mainly detected in the ectodermal tissues. In imaginal disks of third-instar larvae, it is uniformly and homogeneously expressed in eye-antenna, leg, wing and haltere imaginal disks, which is consistent with the former ectodermal expression detected in latestage embryos. Belongs to the ORM family.