May play an important role in neural development; the dorsomedial roof of the third ventricle. Subnuclear distribution. At stage 18, expressed throughout the dorsal central nervous system (CNS), both within the brain and the spinal neural. Strongest expression is observed within the tectum and the cerebellar primordium. Expressed also in the somites, the heart, the branchial arches, and the limb buds. Belongs to the FAM53 family.