Sodium- and chloride-dependent glycine transporter (PubMed:9845349, PubMed:10381548, PubMed:10606742, PubMed:31370103, PubMed:16751771). Terminates the action of glycine by its high affinity sodium-dependent reuptake into presynaptic terminals (PubMed:9845349). May be responsible for the termination of neurotransmission at strychnine-sensitive glycinergic synapses (PubMed:9845349). Lacks sodium- and chloride-dependent glycine transporter activity. Lacks sodium- and chloride-dependent glycine transporter activity. chloride(out) + glycine(out) + 3 Na(+)(out) = chloride(in) + glycine(in) + 3 Na(+)(in) Expressed in medulla, and to a lesser extent in spinal cord and cerebellum. N-glycosylated. The disease is caused by variants affecting the gene represented in this entry. Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. SLC6A5 subfamily.