Substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Probably recognizes and binds to phosphorylated target proteins (By similarity). Regulates protein levels of sulfur metabolism enzymes. The SCF(SKP2) complex may regulate some transcription factors or regulators of cysteine and methionine biosynthesis. Protein modification; protein ubiquitination. Interacts with SKP1. Component of the probable SCF(SKP2) complex containing CDC53, SKP1, RBX1 and SKP2. May interact with ribosomes. Stabilizes the adenosylphosphosulfate kinase MET14 which leads to accumulation H(2)S and SO(2). Present with 432 molecules/cell in log phase SD medium.