Vacuolar multi-drug resistance ABC transporter that may be involved in the transport of bilirubin and glutathione conjugates (By similarity). Plays an important role in virulence. Associates with lipid rafts in a RTA2-dependent manner. Is 10-fold down-regulated during log phase and strongly induced at the diauxic shift. Expression remains high during the postdiauxic phase and continues into stationary phase. Is also up-regulated during the presence of cadmium ions. Leads to decreased sublethal intraperitoneal infection in mice. Belongs to the ABC transporter superfamily.