Plays a role in the regulation of proliferation. Regulates TERT expression by modulating SP1 binding to TERT promoter binding sites. Shuttles between nucleus and cytoplasm. Methylated at Gln-1042 by N6AMT1. Phosphorylation on Ser-1022, Ser-1025 or Ser-1027 is important for cytoplasmic export. Belongs to the NUT family.