Participates in the detoxification of a plethora of hydrazine and arylamine drugs. Acetylates only arylamines. acetyl-CoA + an arylamine = an N-acetylarylamine + CoA There are two forms of NAT2: a rapid isoform (NAT2*21A) and a slow isoform (NAT2*21B). Belongs to the arylamine N-acetyltransferase family.