Transcription repressor. Binds to 5'GCAG-3' core sequence. Required for the specification of corticospinal motor neurons and other subcerebral projection neurons. May play a role in layer and neuronal subtype-specific patterning of subcortical projections and axonal fasciculation. Controls the development of dendritic arborization and spines of large layer V pyramidal neurons (By similarity). May be responsible for mastitis resistance and innate immunity. Highly expressed in brain and weakly in the mammary gland. Infection enhances expression in the mammary gland and promotes expression of SEMA5A. Belongs to the krueppel C2H2-type zinc-finger protein family.