Effector that suppresses flg22-induced post-translational MAP kinase activation both tomato and Arabidopsis. The perception of highly conserved pathogen- or microbe-associated molecular patterns (PAMPs/MAMPs), such as flg22, triggers converging signaling pathways recruiting MAP kinase cascades and inducing transcriptional re-programming, yielding a generic antimicrobial response. The nuclear localization of SFI1 is required for suppression of MAMP-triggered immunity (MTI) signaling in Arabidopsis, and for enhancing P.infestans colonization of N.benthamiana. The RxLR-dEER motif acts to carry the protein into the host cell cytoplasm through binding to cell surface phosphatidylinositol-3-phosphate. Belongs to the RxLR effector family.