Required for centrosome duplication and formation and function of the mitotic spindle. Self-associates. Interacts with pafah1b1 (By similarity). Localizes to the interphase centrosome and to the mitotic spindle. Strongly expressed in the eye, branchial arches and telencephalon of stage 26-33 embryos. Phosphorylated in mitosis. Belongs to the nudE family.