Positive regulator of amino acid starvation-induced autophagy. Homodimer (PubMed:24098481). Interacts with ARL1, ARL2 and ARL3 (PubMed:11303027). Directly interacts with FEZ1 and UVRAG (PubMed:22354037, PubMed:24098481). The interaction with UVRAG is reduced by amino acid starvation, but the complex is stabilized in the presence of FEZ1. Interacts with NRBF2 (PubMed:22354037). Widely expressed with highest levels in brain, heart and skeletal muscle. Belongs to the SCOC family. Truncated N-terminus. Truncated N-terminus.