Involved in the biosynthesis of the anthracycline (aromatic polyketide) antibiotic nogalamycin (PubMed:8760909, PubMed:8668120). Catalyzes the oxygenation of 12-deoxy-nogalonic acid at position 12 to yield nogalonic acid (PubMed:19255477, PubMed:20052967). deoxynogalonate + O2 = H(+) + H2O + nogalonate kcat is 1.5 sec(-1) for monooxygenase activity with dithranol as substrate. Antibiotic biosynthesis. Homodimer.