Induces apoptosis in cooperation with SIAH1A. Acts as a mediator between p53/TP53 and BAX in a neuronal death pathway that is activated by DNA damage. Acts synergistically with TRAF2 and inhibits TNF induced apoptosis through activation of NF-kappa-B (By similarity). Homodimer. Interacts with SIAH1A and SIAH2. Interacts with TRAF2 (By similarity). Expressed at high levels in the cerebellum and at moderate levels in the testis and ovary. The SCAN domain enables PEG3 homo- or heterodimerization to control gene expression in a combinatorial fashion. Belongs to the krueppel C2H2-type zinc-finger protein family.