Component of the nuclear pore complex (NPC), a complex required for the trafficking across the nuclear envelope. Required for proper protein transport into the nucleus. Part of the nuclear pore complex (NPC). Expressed in the developing kidney at stages 26-29 and 33-36, and in the branchial arches at stage 33-36. Morpholino knockdown of the protein causes abnormal heart and gut looping. Belongs to the Nup188 family.