2 glutathione + NADP(+) = glutathione disulfide + H(+) + NADPH Binds 1 FAD per subunit. Xenobiotic degradation; (2,4,5-trichlorophenoxy)acetate degradation. Homodimer. The active site is a redox-active disulfide bond. Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.