May have a role in the cell cycle. AP 3910 has antibacterial activity against B.megaterium. Homodimer. Component of the methylosome, a 20S complex containing at least CLNS1A/pICln, PRMT5/SKB1, WDR77/MEP50, PRMT1 and ERH. Interacts with CHTOP. Belongs to the E(R) family.