Protects DRG1 from proteolytic degradation. Interacts with DRG1; the interaction forms a polysomal DRG1-DFRP1/ZC3H15 complex which provides protein stability to DRG1 possibly by blocking poly-ubiquitination. The DRG1-DFRP2/ZC3H15 complex associates with polysomes. Belongs to the ZC3H15/TMA46 family.