Catalyzes an oxidative deamination of predominantly hydrophobic and aromatic L-amino acids, thus producing hydrogen peroxide that may contribute to the diverse toxic effects of this enzyme (PubMed:17543361, PubMed:2044840). Is very active against L-Lys, L-Phe, L-Leu, L-Tyr, L-Trp, L-Arg, and L-Met, moderately active against L-His, L-cystine, and L-Ile, and slightly active against L-Gln, L-Asn, L-Ala, and L-Val (PubMed:2044840). L-Glu, L-Ser, L-Pro and Gly are oxidized very slowly (PubMed:2044840). Its activity on platelet aggregation is controversial. It has potent inhibitory activity on platelet aggregation induced by ADP and the thromboxane analog U46619, but not by thrombin, mucetin, ristocetin and stejnulxin (PubMed:17543361), but it has also been shown to induce platelet aggregation through the formation of hydrogen peroxide (PubMed:7886693). It binds to bacteria and shows antibacterial activities by generating hydrogen peroxide. Binding and antibacterial activities are higher against Gram-positive than against Gram-negative bacteria. May also have an ability to induce hemorrhage, hemolysis, edema, apoptosis. an L-alpha-amino acid + H2O + O2 = a 2-oxocarboxylate + H2O2 + NH4(+) H2O + L-leucine + O2 = 4-methyl-2-oxopentanoate + H2O2 + NH4(+) H2O + L-phenylalanine + O2 = 3-phenylpyruvate + H2O2 + NH4(+) H2O + L-tryptophan + O2 = H2O2 + indole-3-pyruvate + NH4(+) H2O + L-methionine + O2 = 4-methylsulfanyl-2-oxobutanoate + H2O2 + NH4(+) H2O + L-isoleucine + O2 = (S)-3-methyl-2-oxopentanoate + H2O2 + NH4(+) H2O + L-arginine + O2 = 5-guanidino-2-oxopentanoate + H2O2 + NH4(+) H2O + L-histidine + O2 = 3-(imidazol-5-yl)pyruvate + H2O2 + NH4(+) H2O + L-tyrosine + O2 = 3-(4-hydroxyphenyl)pyruvate + H2O2 + NH4(+) H2O + L-cystine + O2 = (2R)-2-amino-2-carboxylatoethyl-disulfanyl-oxopropanoate + H2O2 + NH4(+) H2O + L-lysine + O2 = 6-amino-2-oxohexanoate + H2O2 + NH4(+) Exhibits unusual thermal stability. At pH 7.4, the enzyme retains full activity after incubation at 25 degrees Celsius for 30 days. Is stable at alkaline condition and is not inactivated by freezing. Homodimer; non-covalently linked. Expressed by the venom gland. N-glycosylated. LD(50) is 5 mg/kg by intravenous injection into mice. Belongs to the flavin monoamine oxidase family. FIG1 subfamily. The existence of two isoforms has been reported, and could explain the differences in sequence and kinetic parameters.