Probable inflammasome component which mediates inflammasome-dependent resistance to bacterial infection by S.typhimurium through association with activated caspa. Self-associates (PubMed:29123523). Interacts with caspa (PubMed:29123523). In the cytoplasm, forms a ring around specks which are large protein aggregates. Expressed in kidney, heart and skin (PubMed:29123523). Not expressed in muscle, ovary, gills, eyes or brain (PubMed:29123523). Highly expressed at fertilization. Up-regulated in response to bacterial infection with S.typhimurium (PubMed:29123523). Highly expressed in macrophages when infected with S.typhimurium (PubMed:29123523). Morpholino knockdown results in reduced caspa activity and impairs caspa activity in response to bacterial infection with S.typhimurium (PubMed:29123523). In addition, larvae have increased susceptibility to the bacterium S.typhimurium (PubMed:29123523).