Multidrug transporter that confers resistance to 5-flucytosine (5-FC) and clotrimazole (PubMed:28066366). Further confers azole drug resistance (PubMed:28066366). Plays direct roles in extrusion of 5-flucytosine and clotrimazole (PubMed:28066366). Expression is regulated by the transcription factors AP1 and PDR1 (PubMed:28066366). Increases the intracellular accumulation of 5-flucytosine and clotrimazole (PubMed:28066366). Belongs to the major facilitator superfamily.