Transcription factor that binds to the inverted palindrome 5'-GTTAATNATTAAC-3'. Binds DNA as a dimer. Can form homodimer or heterodimer with HNF1-alpha-A or -B. Expressed at high level in kidney, liver and intestine. At lower level in lung and testis. Not found in heart, spleen and muscle. Transcription starts at stage 10.5 (mid-gastrula). Belongs to the HNF1 homeobox family.