Possesses antimicrobial activity sensitive to inorganic cations. Has no inhibitory effect on insect gut alpha-amylase. Induces potential changes in fungal membranes and increased K+ efflux and Ca(2+) uptake. Interacts with sphingolipids and ergosterols found in fungal plasma membranes. DmAMP1 expression in heterologous plants such as rice or papaya may provide a broad-spectrum disease resistance. Belongs to the DEFL family.