May be involved in the regulation of the cytoskeleton through interaction with the subpellicular microtubules. May be involved in parasite mobility and attachment to the surface of the host cell. Behaves as a strong immunogen during infection. Monomer. Associated with microtubules. Abundantly expressed in amastigotes and trypomastigotes. In epimastigotes, KMP-11 is expressed at a high level during the logarithmic growth phase but is down-regulated during the stationary phase of growth. There are four copies of the KMP-11 gene in T.cruzi. Belongs to the KMP-11 family.