Plays a role in transcriptional regulation as a repressor that inhibits monoamine oxidase A (MAOA) activity and gene expression by binding to the promoter. Plays an important oncogenic role in mediating the full transforming effect of MYC in medulloblastoma cells. Involved in apoptotic signaling pathways; May act downstream of P38-kinase and BCL-2, but upstream of CASP3/caspase-3 as well as CCND1/cyclin D1 and E2F1. Interacts with MYC (PubMed:15994933, PubMed:16829576). Interacts (via IBM motifs) with PSIP1 (via IBD domain); phosphorylation increases its affinity for PSIP1 (PubMed:16735438, PubMed:25082813, PubMed:29997176). Associates with chromatin. Translocates from cytoplasm to nucleus under dexamethasone induction. Ubiquitous. Overexpressed in medulloblastoma. By MYC overexpression in a concentration dependent manner in neuroblastoma cell line. Phosphorylation increases its interaction with PSIP1. Cells lacking CDCA7L display a reduction of 25-30% of colony formation in medulloblastoma cell lines. CDCA7L overexpression induces colony formation.