May be required for insulin-stimulated glucose transport and glucose transporter SLC2A4/GLUT4 translocation from intracellular glucose storage vesicle (GSV) to the plasma membrane (PM) in adipocytes. May bind phospholipid membranes in a calcium-dependent manner (By similarity). Binds 3 Ca(2+) ions per C2 domain. The C2 domain binds to calcium and membrane lipids.