May mediate cell differentiation events during embryonic development. Homodimer; disulfide-linked. Expressed in the brain. The disease is caused by variants affecting the gene represented in this entry. The disease is caused by variants affecting the gene represented in this entry. The disease is caused by variants affecting the gene represented in this entry. The disease is caused by variants affecting the gene represented in this entry. This protein is produced by a bicistronic gene which also produces the CERS1 protein from a non-overlapping reading frame. Belongs to the TGF-beta family.