Homodimer. Binds to heparin and chondroitin sulfate E. Localizes to the podocyte major processes. Colocalized with the major process protein VIM throughout podocyte development. In the kidney expressed only by podocytes, wherein they localize to major processes. Detected at the vesicle stage of developing glomeruli, expressed in invading endothelial cells in the glomerular cleft at the S-shaped stage and is later expressed only at the basal aspect of maturing podocytes. May be cleaved at Lys-295 after secretion. O-glycosylated but not N-glycosylated.