Gamma-conotoxins may act on voltage-gated non-specific cation pacemaker channels (HCN). Triggers depolarization and firing of action potential bursts in the caudodorsal neurons of lymnaea. This effect is due to activation or enhancement of a slow inward cation current that may underlie endogenous bursting activity of these neurons. Expressed by the venom duct. The presence of a 'disulfide through disulfide knot' structurally defines this protein as a knottin. The cysteine framework is VI/VII (C-C-CC-C-C). Belongs to the conotoxin O2 superfamily.