Beta toxins bind voltage-independently at site-4 of sodium channels (Nav) and shift the voltage of activation toward more negative potentials thereby affecting sodium channel activation and promoting spontaneous and repetitive firing (By similarity). Is toxic to both insect and mammals. Induces paralysis in Acheta domestica crickets, but does not induce death, whereas intracerebroventricular injection into mice causes immediate death (at a dose of 0.05 ug/g). Expressed by the venom gland. Has the structural arrangement of an alpha-helix connected to antiparallel beta-sheets by disulfide bonds (CS-alpha/beta). Monoisotopic mass. Belongs to the long (4 C-C) scorpion toxin superfamily. Sodium channel inhibitor family. Beta subfamily.