Plays a role in axonemal structure organization and motility. Involved in axonemal pre-assembly of inner and outer dynein arms (IDA and ODA, respectively) for proper axoneme building for cilia motility (By similarity). May act by indirectly regulating transcription of dynein proteins (By similarity). Interacts with LRRC6. Localizes to sites proximal to the axoneme. Ciliopathy phenotypes: appearance of 3 otoliths, kidney cysts and dilated kidney tubules at 2.5 days post-fertilization (dpf). Motile cilia in the kidney show disorganized cilia bundles with either severely reduced beat amplitude or paralysis. Olfactory motile cilia are nearly completely paralyzed. Belongs to the ZMYND10 family.