Regulates intracellular concentrations of taurine and glutamate (By similarity). Negatively modulates SLC1A1/EAAC1 glutamate transport activity by decreasing its affinity for glutamate in a PKC activity-dependent manner (PubMed:12119102, PubMed:18684713). Plays a role in the retention of SLC1A1/EAAC1 in the endoplasmic reticulum (By similarity). Homodimer. Heterodimer with ARL6IP1 (PubMed:18684713). Forms multimers. Interacts with ARL6 (PubMed:10508919). Interacts with prenylated RAB1A and RAB3A. Interacts with SLC1A1/EAAC1 (PubMed:18684713, PubMed:12119102). Interacts with RTN2 (via first transmembrane domain) (By similarity). Does not interact with VAMP1, VAMP2 or VAMP3 (By similarity). Also exists as a soluble form in the cytoplasm. Associated with microtubules. Expressed in the cerebral cortex, cerebellum, hippocampus, olfactory bulbs, medulla oblongate and limbic system (at protein level) (PubMed:18684713). Ubiquitous. By methyl-beta-cyclodextrin. Up-regulated upon chronic morphine injection, in amygdala only, other brain regions remain unaffected. Induction by morphine may affect glutamate uptake in the amygdala, causing mice to develop morphine tolerance and dependence (PubMed:12438930). Was originally reported to be induced by retinoic acid (PubMed:12562531). Belongs to the PRA1 family. Wrong choice of frame.