Suppressor of RNA-mediated gene silencing, also known as post-transcriptional gene silencing (PTGS), a mechanism of plant viral defense that limits the accumulation of viral RNAs (PubMed:24450775, PubMed:30791535). The P0 protein suppresses local PTGS using its F-box-like domain to mediate destabilization and degradation of the AGO1 protein, although not via an interaction with host SKP1A (PubMed:24450775). Participates, together with the proteins P1 and P7, in the inhibition of the induction of aphid-induced host phytohormones (PubMed:31758809). This could play a role in the attraction to the infected plants by aphids (PubMed:31758809). The F-box-like domain is required for suppression of host RNA silencing. Belongs to the polerovirus P0 protein family.