Determines polarized sorting of synaptic vesicle (SV) proteins to the axons by excluding SV proteins from the dendrite-specific transport machinery in the Golgi. Role in stress response. Appears to antagonize the effects of pink-1 both in the regulation of axon guidance and stress response. ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein] ATP + L-threonyl-[protein] = ADP + H(+) + O-phospho-L-threonyl-[protein] Expressed in cell bodies, but not in dendritic or axonal processes, of adult head neurons. Also present in non-neuronal tissues, such as the body wall musculature and the epithelial cells of the nematode vulva. Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. ROCO subfamily.