Involved in transcription repression and activation (By similarity). Required for larvae and pupal development, and for normal innate immune responses (PubMed:24947515). Involved in modulating the activation of the immune deficiency pathway (Imd), acting either downstream of, or at the level of, the NF-kappa-B factor Rel (PubMed:24947515). Possibly functions with akirin to regulate Rel, and its interaction with the Brahma complex protein Bap55 suggests that it may regulate the IMD pathway at the level of chromatin remodeling (PubMed:24947515). Interacts with Rel. Interacts with akirin and Bap55. RNAi-mediated knockdown is larval or pupal lethal. RNAi-mediated knockdown in adults results in reduced expression of the antimicrobial peptide genes DptA and Dro in response to septic injury with Gram-negative bacteria E.coli. Adults infected with the Gram-positive bacteria M.luteus display increased expression of the antimicrobial peptide gene Drs.