Alpha-conotoxins act on postsynaptic membranes, they bind to the nicotinic acetylcholine receptors (nAChR) and thus inhibit them. This toxin inhibits alpha-3 containing subunit nAChR (alpha-beta-2/CHRNA3-CHRNB2 with IC(50)=33 nM (rat)/132.4 nM (human)), and alpha-3-beta-4/CHRNA3-CHRNB4 with IC(50)=97 nM (rat)/45.6 nM (human) (PubMed:22108175, PubMed:27646000). In addition, it also inhibits alpha-7/CHRNA7 nAChR with IC(50)=103-210 nM (human)/41 nM (rat) nAChRs (PubMed:22108175, PubMed:30025921). Expressed by the venom duct. The cysteine framework is I (CC-C-C). Alpha4/7 pattern. Monoisotopic mass. Does not inhibit muscle (alpha-beta-gamma-delta) and neuronal alpha-4-beta-2 and alpha-9-alpha-10 nAChRs. Belongs to the conotoxin A superfamily. Truncated C-terminus.