Cargo-receptor protein involved in the cytoplasm to vacuole transport (Cvt) and in autophagy. Recognizes cargo proteins, such as APE4, LAP3, LAP4 and AMS1 and delivers them to the pre-autophagosomal structure for eventual engulfment by the autophagosome and targeting to the vacuole. Involved in the organization of the preautophagosomal structure (PAS). ATG19 association with cargo protein is required to localize ATG11 to the PAS. Also involved in endoplasmic reticulum-specific autophagic process, in selective removal of ER-associated degradation (ERAD) substrates, and is essential for the survival of cells subjected to severe ER stress. Also plays a role in regulation of filamentous growth. Interacts with the vacuolar aminopeptidase 1 (LAP4) precursor and mature forms. Also interacts with AMS1, APE4, ATG8 ATG11, and UBP3. Also found in other perivacuolar punctate structures. The coiled coil domain is required for the interaction with LAP4. The C-terminal WXXL motif is crucial for ATG8-binding and Cvt pathway. Polyubiquitinated at Lys-213 and Lys-216. Deubiquitination by UBP3 is required for full activity of ATG19. ATG19 is important for yeast autolysis which is the source of several molecules responsible for the quality of wines aged in contact with yeast cells. Present with 1250 molecules/cell in log phase SD medium.