May associate with CD21. May regulate the release of Ca(2+) from intracellular stores. Identified by mass spectrometry in melanosome fractions from stage I to stage IV. By Epstein-Barr virus (EBV). A pair of annexin repeats may form one binding site for calcium and phospholipid. Phosphorylated in response to growth factor stimulation. Seems to bind one calcium ion with high affinity. Belongs to the annexin family.