Energy-dependent efflux pump responsible for decreased drug accumulation in multidrug-resistant cells. ATP + H2O + xenobioticSide 1 = ADP + phosphate + xenobioticSide 2. P.falciparum resistant to the drug chloroquine have multiple copies of the gene coding for MDR. Belongs to the ABC transporter superfamily. ABCB family. Multidrug resistance exporter (TC 3.A.1.201) subfamily.