Plays a role in axonemal structure organization and motility (PubMed:29601588). Involved in axonemal pre-assembly of inner and outer dynein arms (IDA and ODA, respectively) for proper axoneme building for cilia motility (PubMed:29601588). May act by indirectly regulating transcription of dynein proteins (By similarity). Interacts (via C-terminus) with DNAAF11 (via CS domain); this interaction stabilizes DNAAF11 at the protein level. Interacts (via C-terminus) with DNAL1; this interaction stabilizes DNAL1 at the protein level. Interacts with DNAAF4, HSPA8, IQUB, RUVBL2 and DYNTL5. Expressed in the testis. Expressed in the tracheal epithelium (PubMed:29601588). Restricted to regions containing motile cilia (PubMed:23891471). Specifically expressed in the ciliated epithelial layer associated with nasal and lung epithelium in 18.5 dpc embryos. Mice neonates exhibit growth retardation dying within 1 month after birth. Show head deformation and situs invertus (heart apex, stomach, liver or spleen). Display lung lobular structures deterioration and collapsed alveolar spaces. Show mucosal congestion in paranasal cavities. Show loss of ciliary motility and axonemal outer and inner dynein arm (IDA and ODA, respectively) components without disruption of ciliogenesis. Belongs to the ZMYND10 family.