Catalyzes the Claisen rearrangement of chorismate to prephenate. May play some role in the pathogenicity. chorismate = prephenate Tyrosine, phenylalanine, and tryptophan moderately enhance chorismate mutase activity at low concentrations, but allosterically inhibit the enzyme at higher concentrations. kcat is 50 sec(-1) (PubMed:15654876). kcat is 26 sec(-1) (PubMed:15737998). Optimum pH is 7.5. The activity is dramatically affected under alkaline conditions (pH 9.5). Optimum temperature is between 37 to 50 degrees Celsius. An increase in temperature does increase enzyme activity, and complete reversible denaturation of the enzyme occurs at a temperature close to 60 degrees Celsius. Metabolic intermediate biosynthesis; prephenate biosynthesis; prephenate from chorismate: step 1/1. Homodimer. Was identified as a high-confidence drug target. In the presence of high concentrations of tyrosine, phenylalanine, and tryptophan, the enzyme is completely protected from proteolytic degradation.