Hydrolyzes the second messenger cAMP, which is a key regulator of many important physiological processes (By similarity). Antagonizes dorsal D (DD) motor neuron respecification by reducing levels of cAMP (PubMed:29033363). a nucleoside 3',5'-cyclic phosphate + H2O = a nucleoside 5'-phosphate + H(+) Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions. Expressed in dorsal D (DD) motor neurons and several other neurons at the L1 stage. Expression in DD neurons decreases gradually beginning in the late L1 stage. Highly expressed in adult ventral D (VD) motor neurons, but diminished in adult DD motor neurons. Belongs to the cyclic nucleotide phosphodiesterase family.