Receptor for gastrin and cholecystokinin (PubMed:29920282). The CCK-B receptors occur throughout the central nervous system where they modulate anxiety, analgesia, arousal, and neuroleptic activity (Probable). This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system (Probable). Belongs to the G-protein coupled receptor 1 family.