Epsilon-conotoxins act at presynaptic membranes, blocking the calcium channels or G protein-coupled receptors. Causes hyperactivity upon intracranial injection into mice. Causes dorsal fins drooping in fish. Expressed by the venom duct. The cysteine framework is V (CC-CC). O-glycan consists of the disaccharide Gal-GalNAc. Belongs to the conotoxin T superfamily.