NAD-dependent protein deacylase. Catalyzes the NAD-dependent hydrolysis of acyl groups from lysine residues (By similarity). Involved in responses to ethylene leading to the transcriptional repression of some ethylene-responsive genes via the regulation of histone acetylation H3K9Ac (PubMed:29298835). Negatively regulates plant basal defense against plant pathogens, possibly by suppressing salicylic acid biosynthesis (PubMed:20573705). H2O + N(6)-acetyl-L-lysyl-[protein] + NAD(+) = 2''-O-acetyl-ADP-D-ribose + L-lysyl-[protein] + nicotinamide Binds 1 zinc ion per subunit. Binds to the promoter region of genes influenced by ethylene (PubMed:29298835). Interacts with ENAP1; this interaction is enhanced in the presence of ethylene (PubMed:29298835). Repressed by pathogen infection. Reduced ethylene sensitivity in the double mutant srt1 srt2. Belongs to the sirtuin family. Class II subfamily.