Catalytic component of a P4-ATPase flippase complex, which catalyzes the hydrolysis of ATP coupled to the transport of glucosylceramide (GlcCer) from the outer to the inner leaflet of lysosome membranes (By similarity). Plays an important role in the maintenance of lysosome membrane integrity and function in cortical neurons (PubMed:32172343). ATP + H2O + phospholipidSide 1 = ADP + phosphate + phospholipidSide 2. a beta-D-glucosyl-(1<->1')-N-acylsphing-4-enine(out) + ATP + H2O = a beta-D-glucosyl-(1<->1')-N-acylsphing-4-enine(in) + ADP + H(+) + phosphate Component of a P4-ATPase flippase complex which consists of a catalytic alpha subunit ATP10B and an accessory beta subunit TMEM30A. Exit from the endoplasmic reticulum requires the presence of TMEM30A, but not TMEM30B. Expressed in cortical neuron (at protein level). Autophosphorylated at the conserved aspartate of the P-type ATPase signature sequence. Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.