Histatins are salivary proteins that are considered to be major precursors of the protective proteinaceous structure on tooth surfaces (enamel pellicle). In addition, histatins exhibit antibacterial and antifungal activities. Submandibular and parotid glands. Depending on the authors, the form called histatin-2 is alternatively a proteolytic product, or the non-phosphorylated form of histatin-1. Not post-translationally modified. with 1 phosphate group. with 1 phosphate group and 1 sulfate group. with 1 phosphate group and 2 sulfate groups. with 1 phosphate group and 3 sulfate groups. with 1 phosphate group and 4 sulfate groups. The recommended nomenclature of salivary peptides follows published guidelines (PubMed:20973643). In agreement with the authors, it has been decided to indicate the boundaries of the peptides according to the positions within the precursor, and not in the mature protein, as has formerly been proposed. Belongs to the histatin/statherin family.