Lectin involved in innate immunity. Agglutinates all types of human erythrocytes, Gram-positive and Gram-negative bacteria. Has a stronger agglutinating activity towards Gram-negative bacteria than towards Gram-positive bacteria. Specifically recognizes acetyl group-containing substances on agglutinated cells. The hemagglutinating activity was inhibited by EDTA, acetyl group-containing mono- and disaccharides, N-acetyl derivatives of amino acids, other acetyl group-containing substances, propionamide and benzamide. Enhances the antimicrobial activity of big defensin against Gram-positive bacteria but not against Gram-negative bacteria. Multimeric. PubMed:10468566 and PubMed:11707569 are in disagreement about the nature of the multimer, PubMed:10468566 finds hexamers and octamers, the results in PubMed:11707569 suggest tetramers. Strongly expressed in heart and intestine, weakly expressed in hepatopancreas. Not found in hemocytes, stomach, nervous tissue or skeletal muscle.