Substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins including blmp-1 (PubMed:17336909, PubMed:23431138, PubMed:24613396, PubMed:24968003). Heterochronic protein which is required for the timing of gonad development and epidermal seam cell differentiation (PubMed:17336909). Regulates tail-spike cell death through inhibition of the apoptosis regulator ced-9 (PubMed:23431138). Component of a SCF ubiquitin ligase complex (PubMed:17336909, PubMed:23431138, PubMed:24613396, PubMed:24968003). Interacts (via F-box) with skr-1 (PubMed:17336909, PubMed:23431138). Interacts with blmp-1; the interaction targets blmp-1 for proteasomal degradation (PubMed:24613396). Interacts with ced-9; the interaction inhibits ced-9 activity, either directly or indirectly (PubMed:23431138). In mid-embryogenesis, expression is most prominent in epidermal and intestinal cells (PubMed:17336909). By the 1.5-fold stage of embryogenesis, expression is additionally detected in neurons and other cells (PubMed:17336909). During larval and adult stages, highest expression is seen in epidermal seam cells and hypodermis (PubMed:17336909). In larvae, strongly expressed in the P epidermal blast cells and descendents that give rise to the vulva and weakly expressed in the somatic gonad, including the gonadoblasts, the anchor cell and the distal tip cells (PubMed:17336909). Some weak expression also seen in adult spermatheca and uterus (PubMed:17336909). In the musculature, expressed in the pharynx, anal depressor, sex muscles, and body wall muscles. Detected in neurons of the head, tail, ventral cord and periphery (PubMed:17336909). Also expressed in the embryonic tail spike cell (PubMed:23431138). Expression is first detected during mid-embryogenesis with high levels in larvae and low levels in adults. Most mutants arrest as three-fold embryos that fail to hatch and those that hatch arrest in L1 with many animals appearing uncoordinated and misshapen (PubMed:17336909). 7- to 8-fold increase in blmp-1 levels in seam and hypodermal cells (PubMed:24613396).