Effector that suppresses plant defense responses during the early stages of pathogen infection. Suppresses cell death induced by effectors and PAMPs in plant hosts (PubMed:21653195, PubMed:23550527). Triggers a hypersensitive response (HR) in the presence of Rps1d (PubMed:23550527, PubMed:23594349). Suppresses BAX-induced cell death and enhanced P.capsici infection in Nicotiana benthamiana. Also suppresses effector-triggered immunity induction by associating with Avr1b and Rps1b, suggesting a role in suppressing plant immunity (PubMed:23594349). Expression is strongly up-regulated during the early stages of infection. The RxLR-dEER motif acts to carry the protein into the host cell cytoplasm through binding to cell surface phosphatidylinositol-3-phosphate. Leads to the gain of virulence via impairing effector-triggered immunity (ETI) allowed by host resistance (R) protein Rps1d. Avh6 is present in P.sojae strains that are avirulent on Rps1d hosts, whereas the gene is deleted from the genome of virulent strains. Belongs to the RxLR effector family.