Belongs to the disease resistance NB-LRR family. RPP8/HRT subfamily. Has been shown to confer susceptibility to the fungus Cochliobolus victoriae by conditioning victorin-dependent (victorin is a toxin synthesized by C.victoriae) induction of defense-associated proteins in cv. Cl-0 (AC A7XGN8). In strain cv. Bay-0, 2 variations at positions 228 (Thr -> Ala) and 538 (Arg -> Ser) result in an inactive LOV1 protein regarding sensitivity to victorin. The sequence shown is from strain cv. Bay-0, a complete sequence for LOV1 can be found in strain cv. Cl-0 (AC A7XGN8). Functional and comparative genomics of disease resistance gene homologs