Palmitoyl acyltransferase that mediates palmitoylation of proteins and is required during embryonic heart development. Involved in the proliferation of neural stem cells by regulating the FGF/ERK pathway (By similarity). Involved in the proliferation of neural stem cells by regulating the FGF/ERK pathway (PubMed:26663717). hexadecanoyl-CoA + L-cysteinyl-[protein] = CoA + S-hexadecanoyl-L-cysteinyl-[protein] Expressed in the central nervous system (CNS) (PubMed:26663717). Expressed in the developing forebrain, and especially in the telencephalon (PubMed:26663717). Maternally expressed in the at four-cell stage. Highly expressed in the developing anterior neural plate since tailbud stage. During the segmentation period, 24 hour post fertilization (hpf), expression is still enriched in cell clusters at prosencephalon and mesencephalon. The DHHC domain is required for palmitoyltransferase activity. Morpholino knockdown of the protein causes malformation in telencephalon (PubMed:26663717). Impaired neural stem/progenitor cells (NSPCs) proliferation in the telencephalon (PubMed:26663717). Belongs to the DHHC palmitoyltransferase family.