May play a role in cell-cycle-dependent microtubule organization. Interacts with PLEKHG6. Interacts with ARMC9, TOGARAM1, CCDC66, CEP104 and CEP290 (PubMed:32453716). Associated with mitotic spindles. Expressed in adult and fetal brain with enrichment in the cerebellum. Detected in testis. Isoform 1 expression increases throughout the cell cycle and peaks in G2/M phase. Isoform 2 expression is highest in G1 phase and decreases thereafter. Phosphorylated. Phosphorylation increases in colcemide-treated cells. The disease is caused by variants affecting the gene represented in this entry. Truncated N-terminus.