Phosphodiesterase (PDE) that catalyzes the hydrolysis of cyclic-di-GMP (c-di-GMP) to 5'-pGpG. cyclic di-3',5'-guanylate + H2O = 5'-phosphoguanylyl(3'->5')guanosine + H(+) Expressed at both 28 and 37 degrees Celsius during exponential growth. Repressed by RpoS. Was originally (Ref.4) thought to originate from Proteus vulgaris, but was shown to originate from E.coli.