Mitochondrial solute carriers shuttle metabolites, nucleotides, and cofactors through the mitochondrial inner membrane. Specifically mediates the transport of S-adenosylmethionine (SAM) into the mitochondria. Strongly inhibited by tannic acid and Bromocresol Purple. Widely expressed. Highly expressed in testis, with moderate expression in brain, heart, kidney, lung, skeletal muscle, pancreas, small intestine and liver, and low expression in spleen. The disease is caused by variants affecting the gene represented in this entry. Belongs to the mitochondrial carrier (TC 2.A.29) family.