Acts as Baeyer-Villiger monooxygenase on a broad range of substrates. Catalyzes the insertion of an oxygen atom into a carbon-carbon bond adjacent to a carbonyl, which converts ketones to esters (By similarity). Active on diverse carbonyl compounds, whereas soft nucleophiles are mostly non- or poorly reactive. In contrast with other forms of FMO it is non- or poorly active on 'classical' substrates such as drugs, pesticides, and dietary components containing soft nucleophilic heteroatoms (PubMed:7872795). Able to oxidize drug molecules bearing a carbonyl group on an aliphatic chain, such as nabumetone and pentoxifylline. Also, in the absence of substrates, shows slow but yet significant NADPH oxidase activity (By similarity). Acts as a positive modulator of cholesterol biosynthesis as well as glucose homeostasis, promoting metabolic aging via pleiotropic effects (By similarity). H(+) + N,N-dimethylaniline + NADPH + O2 = H2O + N,N-dimethylaniline N-oxide + NADP(+) H(+) + NADPH + O2 = H2O2 + NADP(+) H(+) + heptan-2-one + NADPH + O2 = H2O + NADP(+) + pentyl acetate H(+) + NADPH + O2 + octan-3-one = H2O + NADP(+) + pentyl propanoate H(+) + NADPH + O2 + octan-3-one = ethyl hexanoate + H2O + NADP(+) H(+) + hexan-3-one + NADPH + O2 = ethyl butanoate + H2O + NADP(+) H(+) + hexan-3-one + NADPH + O2 = H2O + NADP(+) + propyl propanoate H(+) + heptan-4-one + NADPH + O2 = H2O + NADP(+) + propyl butanoate (2E)-geranial + H(+) + NADPH + O2 = (1E)-2,6-dimethylhepta-1,5-dien-1-yl formate + H2O + NADP(+) H(+) + NADPH + O2 + sulcatone = 4-methylpent-3-en-1-yl acetate + H2O + NADP(+) Kidney and liver. Belongs to the FMO family.