Acyltransferase required for the fatty acid remodeling of phosphatidylinositol (1,2-diacyl-sn-glycero-3-phosphoinositol or PI). Mediates the conversion of lysophosphatidylinositol (2-acylglycerophosphatidylinositol or LPI) into PI (LPIAT activity). Has preference for saturated and mono-unsaturated fatty acids as acyl donors and sn-2-acyl lysoPI (2-acyl-sn-glycero-3-phospho-D-myo-inositol) as acyl acceptor. Contributes to the asymmetric cell division of epithelial cells. Asymmetric cell division is the fundamental mechanism by which multicellular organisms generate cell diversity. a 2-acyl-sn-glycero-3-phospho-D-myo-inositol + an acyl-CoA = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + CoA a 2-acyl-sn-glycero-3-phospho-D-myo-inositol + octadecanoyl-CoA = 1-octadecanoyl-2-acyl-sn-glycero-3-phospho-(1D-myo-inositol) + CoA Phospholipid metabolism; phosphatidylinositol metabolism. Expressed in seam cells, vulval epithelial cells and the major epithelial syncytium hyp7, and in several head neurons including AIY interneurons. Mutants showed defects in vulval morphology and in the asymmetric division of stem cell-like epithelial cells. Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.