Inhibitor of neuronal axonal outgrowth. Acts as a negative regulator of CDC42 and STAT3 and a positive regulator of STMN2. Positive regulator of CDC27. May form homodimers (By similarity). May interact with DAZAP2, FAM168A, PRDX6, RBM6, TMTC1 and YPEL2 (By similarity). Interacts with CDC27 (PubMed:20716133). Expressed in neuronal cell bodies and axonal fibers. Predominantly expressed in the brain, including olfactory bulb, cortex and cerebellum (at protein level). Specifically expressed in differentiated neurons, but absent from proliferating neural stem cells. Up-regulated by different neurotrophins, including NGF and BDNF, but not by growth factors, such as EGF. N-glycosylated. Belongs to the FAM168 family. Extended N-terminus.