Hydrolyzes ADP with high activity. Shows weak or no activity on 5'-AMP, 5'-GMP, 3'-AMP, ATP, cAMP, and cGMP (By similarity). Is devoid of monophosphatase and proteinase activities (By similarity). Inhibits ADP-induced platelet aggregation and is cytotoxic to human keratinocytes (PubMed:33636276). Kinetic parameters indicated a higher affinity for the substrate bis(p-nitrophenyl) phosphate compared to others snake venom PDEs (PubMed:33636276). Is recognized by the crotalid antivenom produced by the Instituto Butantan (PubMed:33636276). ADP + H2O = AMP + H(+) + phosphate Binds 2 divalent metal cations per subunit. Optimum pH is 8.0-8.5. Optimum temperature is 37 degrees Celsius. Monomer. Expressed by venom gland. N-glycosylated. Glycosylation counts for an increased mass of ~9%. Contains 16 disulfide bonds. Isoform/Glycoform-1. Isoform/Glycoform-2. Belongs to the nucleotide pyrophosphatase/phosphodiesterase family.