May play a role in DNA-protein cross-links (DPCs) clearance, ensuring the genomic stability by protecting germ cells and early embryos from various sources of damage. Co-localizes with SUMO2 at PML bodies in all interphase cells (By similarity). Localizes on condensed chromosomes in spermatocytes in G2 and M during meiotic prophase (By similarity). Progeny of mutant females display widespread morphological defects and cell death and early embryos have asynchronous mitotic divisions and tangled chromosomes. Belongs to the serine-aspartate repeat-containing protein (SDr) family.