Binds with high affinity to muscular (alpha-1/CHRNA1) and neuronal (alpha-7/CHRNA7) nicotinic acetylcholine receptor (nAChR) and inhibits acetylcholine from binding to the receptor, thereby impairing neuromuscular and neuronal transmission (By similarity). Mice injected with this toxin develop flaccid paralysis followed by death. Irreversibly inhibits twitches in a concentration-dependent manner in rat phrenic nerve-hemidiaphragm and chick biventer cervicis muscle (PubMed:19728988). Monomer in solution, homodimer in crystal state. Expressed by the venom gland. LD(50) is 0.16 ug/g by intravenous injection into mice. Belongs to the snake three-finger toxin family. Long-chain subfamily. Type II alpha-neurotoxin sub-subfamily.