Alpha-conotoxins act on postsynaptic membranes, they bind to the nicotinic acetylcholine receptors (nAChR) and thus inhibit them. Shows inhibition on alpha-3-beta-2/CHRNA3-CHRNB2 (IC(50)=75 nM), alpha-7/CHRNA7 (IC(50)=637 nM) and alpha-9-alpha-10/CHRNA9-CHRNA10 nAChRs (IC(50)=1000 nM). In addition, it also shows inhibition on high-voltage activated (HVA) calcium channels currents (30% at 100 nM) that are mediated by GABA(B) receptors (GABBR1 and GABBR2). Expressed by the venom duct. Mostly expressed in embryos. Also slightly expressed in adults, but the toxin is not found in adult venom. The cysteine framework is I (CC-C-C). Alpha4/7 pattern. Does not show activity on alpha-3/beta-4 (CHRNA3/CHRNB4), alpha-4/beta-2 (CHRNA4/CHRNB2) and alpha-4/beta-4 (CHRNA4/CHRNB4) acetylcholine receptors. Belongs to the conotoxin A superfamily.