Serine protease. Hydrolyzes the alpha chains of fibrin and fibrinogen completely, has lower activity on the beta and gamma chains of fibrin and fibrinogen. Inhibited by the serine protease inhibitors DFP, PMSF and TLCK. Not inhibited by the serine protease inhibitors aprotinin, elastinal, SBTI and benzamidine, the cysteine protease inhibitors iodoacetate and E64, or the metalloprotease inhibitors EDTA and EGTA. Optimum pH is 7.8. Active from pH 4.0 to pH 9.0. Optimum temperature is 45 degrees Celsius. Active from 30 to 55 degrees Celsius. Monomer. Body cavity. Belongs to the peptidase S8 family. The order of the peptides shown is unknown.