PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. Seems to be involved in root development. [protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0) Binds cyclosporin A (CsA). CsA mediates some of its effects via an inhibitory action on PPIase (By similarity). Interacts with the PP2A A subunit PP2AA1/RCN1. Ubiquitous, mostly in aerial organs. Higher levels in leaf and buds, and lower levels in seedlings. Belongs to the cyclophilin-type PPIase family.