Transcription factor involved in the regulation of calcium ion homeostasis (PubMed:18298443). Regulates genes encoding calcium transporters, transcription factors and genes that could be directly or indirectly involved in calcium metabolism (PubMed:20078882). Supports especially pmcA, pmcB and pmcC expression encoding for calcium-translocating P-type ATPases (PubMed:18298443, PubMed:22649543). Binds target promoters at motif A[GT][CG]CA[AC][AG] (PubMed:25196896). Plays an essential role germination, radial growth, and asexual development (PubMed:18456861, PubMed:18298443). Also plays a major role in proper chitin and glucan incorporation into the cell wall (PubMed:19015336). Involved in the high-osmolarity glycerol response (HOG) signaling pathway (PubMed:25196896). Required for pathogenicity in an experimental murine model of invasive pulmonary aspergillosis (PubMed:18456861, PubMed:18298443, PubMed:22649543, PubMed:25196896). Localizes predominantly to the cytosol of the cell in the absence of added calcium and translocates to the nucleus following exposure to CaCl(2). Leads to reduced levels of beta-1,3-glucan in the cell wall and impairs pathogenicity in an experimental murine model of invasive pulmonary aspergillosis (PubMed:18456861, PubMed:18298443, PubMed:19015336). Increases sensitivity to heat shock (PubMed:18298443).