May play a role in neuronal migration during embryonic development. In the developing neocortex, expression is detected at embryonic day 12 (E12) and peaks at E14. Then expression levels decrease until postnatal day 5 (P5) and increase again at least until P30. RNAi-mediated knockdown of the protein, performed in utero by electroporation in lateral ventricle of E15 embryos, results in a massive neuronal migration defect and in the development of heterotopic nodules along the walls of the lateral ventricles. At E20, a significant arrest of cells within the ventricular zone is observed, while, at this stage in control embryos, cells have reached the cortical plate.