NAD-dependent protein deacylase. Catalyzes the NAD-dependent hydrolysis of acyl groups from lysine residues. Plays a role in oxidative stress resistance (PubMed:23438705). H2O + N(6)-acetyl-L-lysyl-[protein] + NAD(+) = 2''-O-acetyl-ADP-D-ribose + L-lysyl-[protein] + nicotinamide Binds 1 zinc ion per subunit. Interacts with pyc-1, pcca-1 and mccc-1. Ubiquitously expressed with high expression in the pharynx, body wall muscles and gonad. Expression is first detected at the three-fold stage during embryogenesis. This protein may be expected to contain an N-terminal transit peptide but none has been predicted. Belongs to the sirtuin family. Class II subfamily.