High-affinity permease for arginine (PubMed:8436127, PubMed:9231419, PubMed:10654085, PubMed:11746604). Interacts with RRT2 (PubMed:21880895). Recycled via the retromer-mediated pathway (PubMed:21880895). Requires phosphatidyl ethanolamine (PE) for localization and exclusively associated with lipid rafts called MCCs (membrane compartment occupied by CAN1) (PubMed:12100990, PubMed:14551254, PubMed:21223946). Phosphorylated probably at multiple sites (PubMed:9544242). Abolishes canavanine sensitivity (PubMed:3327612). Extends replicative lifespan and leads to distinct changes in transcriptional and translational profiles, including translational activation of the GCN4 transcription factor (PubMed:28228255). Belongs to the amino acid-polyamine-organocation (APC) superfamily. YAT (TC 2.A.3.10) family.