Has antiparasitic activity against promastigote forms of L.major, and antibacterial activity against Gram-positive bacterium S.aureus. Has antifungal activity against the yeasts C.albicans and S.cerevisiae, but not C.glabrata. Has antifungal activity against filamentous fungi A.fumigatus, F.culmorum, F.oxysporum, N.crassa, T.viride and T.mentagrophytes, but not B.bassiana. Is synthesized by the fat body and eventually secreted into the hemolymph. By bacterial and parasitic hemolymph and gut infections. Expression peaks at 24 hours post infection by bacterium P.carotovorum, and at day four post infection by the parasite L.major. Belongs to the invertebrate defensin family. Type 1 subfamily.