Magnesium-independent aromatic prenyltransferase that catalyzes the irreversible transfer of a dimethylallyl group to 4-hydroxyphenylpyruvate to produce the ring A structure in the novobiocin biosynthesis pathway. Novobiocin is an aminocoumarin family antibiotic that targets bacterial DNA gyrases. It is able to prenylate many different compounds, including the phenylpropanoids 4-coumarate and caffeate, the plant polyketide resveratrol, the (iso)flavonoid naringenin, apigenin, daidzein and genistein, and the dihydroxynaphthalenes 1,6-DHN and 2,7-DHN. 3-(4-hydroxyphenyl)pyruvate + dimethylallyl diphosphate = 3-dimethylallyl-4-hydroxyphenylpyruvate + diphosphate Optimum pH is 7. Optimum temperature is between 30 and 40 degrees Celsius. Antibiotic biosynthesis; novobiocin biosynthesis. Monomer. Belongs to the aromatic prenyltransferase family.