Component of the mst2 complex which is a highly specific H3 lysine 14 (H3K14) acetyltransferase that functions together with gcn5 to regulate global levels of H3K14 acetylation (H3K14ac), critical for DNA damage checkpoint activation. May also function as a sugar alcohol (polyol) phosphatase that prevents accumulation of toxic levels of polyol phosphates, which can impair glycolysis by inhibiting glucose-6-phosphate isomerase. D-ribitol 5-phosphate + H2O = phosphate + ribitol D-sorbitol 6-phosphate + H2O = D-sorbitol + phosphate H2O + sn-glycerol 1-phosphate = glycerol + phosphate D-erythrose 4-phosphate + H2O = D-erythrose + phosphate Component of the mst2 complex composed of at least eaf6, mst2, nto1, pdp3, ptf1, ptf2 and tfg3. Belongs to the HAD-like hydrolase superfamily.