May be able to insert into the membrane in both orientations. Depletion of SecE or YidC does not affect membrane insertion. Expressed in exponential phase, strongly induced in stationary phase (PubMed:19121005) and in minimal glucose or glycerol medium, in low oxygen, by SDS/EDTA (envelope stress) and by H(2)O(2) (PubMed:19734316) (at protein level).