Calcium-dependent lectin that acts as a pattern recognition receptor (PRR) of the innate immune system: specifically recognizes and binds alpha-mannans on C.albicans hypheas (By similarity). Binding of C.albicans alpha-mannans to this receptor complex leads to phosphorylation of the immunoreceptor tyrosine-based activation motif (ITAM) of FCER1G, triggering activation of SYK, CARD9 and NF-kappa-B, consequently driving maturation of antigen-presenting cells and shaping antigen-specific priming of T-cells toward effector T-helper 1 and T-helper 17 cell subtypes (By similarity). Recognizes also, in a mannose-dependent manner, allergens from house dust mite and fungi, by promoting cysteinyl leukotriene production. Recognizes soluble elements from the eggs of Shistosoma mansoni altering adaptive immune responses (By similarity). Associated with FCER1G (By similarity). Heterodimer with CLEC4D; this heterodimer forms a pattern recognition receptor (PRR) against fungal infection (By similarity). Expressed at the highest levels in lymph nodes, at moderate levels in skin, small intestine, liver, and lung, and at lower levels in abomasum and spleen, but is not in the brain. Abundantly expressed by Langerhans cells compared to macrophages. A short stretch of the intracellular domain (AA 8-14) proximal to the transmembrane domain is required for association with Fc receptor gamma chain.