May play a role in mitochondrial aerobic respiration. May also regulate mitochondrial organization and fission. May be associated with the inner and the outer mitochondrial membrane. Ubiquitously expressed with higher expression in testis. Mice are viable and fertile. However, oxidative DNA damages appear in the testis, associated with a reduced expression of genes encoding enzymes with oxidoreductase activity. Belongs to the MTFR1 family.