Fungal growth inhibitors. Neither CB-HEL nor CD-HEL have chitinase activity, but both have antimicrobial activities. CD-HEL has RNase, but no DNase activity. CB-HEL interacts strongly with a fungal fruiting body lectin. associated with the tonoplast. Up-regulated by ethylene, methyl jasmonate, wounding and virus infection. Weakly induced by salicylic acid and 2,6-dichlorisonicotinic acid. The C-terminal vacuolar sorting signal (VSS) (194-212) is required for vacuolar localization.