Has minor, but significant effects on the Para/tipE insect sodium channel. Expressed by the venom gland. The presence of a 'disulfide through disulfide knot' structurally defines this protein as a knottin. LD(50) is 27 +- 11 ug/g in crickets. Has no effect of mammalian sodium channels Nav1.2/SCN2A, Nav1.4/SCN4A, Nav1.5/SCN5A, Nav1.6/SCN8A and potassium channels Kv1.3/KCNA3 and Shaker IR. Belongs to the neurotoxin 14 (magi-1) family. 08 (Ltx-4) subfamily.