Key transcriptional regulator of carbohydrate metabolism. Binds the promoter sequences of the glycolytic genes at the CANNTG motif and activates their expression during growth on either fermentable or non-fermentable carbon sources as well as under hypoxic growth conditions. Complete glycolytic activation by GAL4 and TYE7 is required for full virulence. Involved in biofilm formation and negatively regulates hyphal formation under hypoxia. Controls also the expression of the copper transport protein CTR1. Efficient DNA binding requires dimerization with another bHLH protein. Expression is controlled by RTG1 and is down-regulated during mating process, yeast-to-hyphal transition, and in presence of benomyl, amphotericin B, and caspofungin.