Kappa-conotoxins bind and inhibit voltage-gated potassium channels. This toxin inhibits the mammalian potassium channels Kv1.1/KCNA1 and Kv1.3/KCNA3. Expressed by the venom duct. The cysteine framework is XI (C-C-CC-CC-C-C). Contains 4 disulfide bonds. Here are reported disulfide bonds proposed in [PubMed:16268797], even if the connectivity known for the framework XI is I-IV, II-VI, III-VII, V-VIII. This toxin has no effects on Kv1.2/KCNA2, Kv11/KCNH, and Kir2.1/KCNJ2 potassium channels, and on Nav1.5/SCN5A sodium channels. Belongs to the conotoxin I2 superfamily.