Ribosomal protein P0 is the functional equivalent of E.coli protein L10. P0 forms a pentameric complex by interaction with dimers of P1 and P2. Causes an allergic reaction in horses. Binds to IgE of 19 horses from Switzerland suffering from insect bite hypersensitivity (IBH), a recurrent seasonal dermatitis of the horse, caused by bites of Culicoides (midge) and sometimes Simulium (black fly) species. Binds to IgE of all 18 healthy control horses from Switzerland exposed to the bites of these insects, and of 8 horses from Iceland which had not been exposed to Culicoides midges. There is no significant difference in IgE-binding between the three groups of horses. Does not induce sulfidoleukotriene (sLT) release from peripheral blood leukocytes (PBLs) in any of the 5 horses tested affected by IBH. Belongs to the universal ribosomal protein uL10 family.