Cell adhesion, ankyrin-binding protein which may be involved in neurite extension, axonal guidance, synaptogenesis, myelination and neuron-glial cell interactions. Horseshoe-shaped homodimer. Probable constituent of a NFASC/NRCAM/ankyrin-G complex. Associates with the sodium channel beta-1 (SCN1B) and beta-3 (SCN3B) subunits. Interacts with GLDN/gliomedin (By similarity). Interacts with MYOC. Homophilic adhesion is primarily mediated by the interaction of the second Ig-like domains. The disease is caused by variants affecting the gene represented in this entry. May be due to intron retention. May be due to intron retention. Belongs to the immunoglobulin superfamily. L1/neurofascin/NgCAM family.