Myosin is a hexamer of 2 heavy chains and 4 light chains. Expressed in tail muscle (at protein level). Causes an allergic reaction in human. Binds to IgE of patients allergic to shrimp (PubMed:18760458, PubMed:20471069, PubMed:22192087). Natural boiled protein binds to IgE in 55% of the 38 shrimp-allergic patients tested. Recombinant protein binds to IgE in 89% of the 19 patients tested allergic to the natural protein (PubMed:18760458). Epitope diversity and the frequency and intensity of IgE-binding is significantly more pronounced in children than in adults (PubMed:20471069). Patients (children or adults) with positive double-blind placebo-controlled food challenge (DBPCFC) to shrimp have a more frequent, intense and diverse recognition of the epitopes of this protein than those with negative challenge (PubMed:22192087).