Involved in poly(A) tail length control in neuronal cells. Binds the polyadenosine RNA oligonucleotides. Interacts with HOOK2 (PubMed:19273536). Interacts with ZFC3H1 in a RNase-sensitive manner (PubMed:27871484). Colocalizes with poly(A) RNA in nuclear speckles. Isoform 1 and isoform 6 are expressed in fetal and adult brain. Isoform 1 and isoform 6 are expressed in fetal and adult temporal lobe. The disease is caused by variants affecting the gene represented in this entry. ZC3H14 can functionally substitute for Nab2 in fly neurons and can rescue defects in development and locomotion that are present in dNab2 null flies. Belongs to the ZC3H14 family. Several sequencing errors. Aberrant splicing. Aberrant splicing.