May be involved in transcriptional regulation as a transcriptional corepressor. The DEPDC1A-ZNF224 complex may play a critical role in bladder carcinogenesis by repressing the transcription of the A20 gene, leading to transport of NF-KB protein into the nucleus, resulting in suppression of apoptosis of bladder cancer cells. Isoform 2 and isoform 5 can form homodimers and heterodimers. Interacts with ZNF224. Colocalizes with ZNF224 at the nucleus. Expressed in testis. Up-regulated in bladder cancer cells (at protein level). Contaminating sequence. Potential poly-A sequence. Truncated N-terminus. Truncated N-terminus. Probable cloning artifact.