Has caseinolytic activity. Causes hemorrhage on rabbit skin and causes myonecrosis in mouse tibialis anterior muscle. Inhibits platelet aggregation. Cleavage of 5-His-|-Leu-6, 10-His-|-Leu-11, 14-Ala-|-Leu-15, 16-Tyr-|-Leu-17 and 24-Phe-|-Phe-25 in insulin B chain. Binds 1 zinc ion per subunit. Inhibited by EDTA and EGTA. Monomer. Expressed by the venom gland. The metalloproteinase domain which is released from the cleavage of the disintegrin bothropasin may be unstable. Belongs to the venom metalloproteinase (M12B) family. P-III subfamily. P-IIIb sub-subfamily.