Component of the small ribosomal subunit (PubMed:8706699). Required for proper rRNA processing and maturation of 18S rRNAs (PubMed:25424902). Binds 1 zinc ion per subunit. Component of the small ribosomal subunit. Expressed in a wide variety of actively proliferating cells and tumor tissues. The disease is caused by variants affecting the gene represented in this entry. Belongs to the eukaryotic ribosomal protein eS27 family. Was originally (PubMed:8407955) thought to be a protein that could have played a role as a potentially important mediator of cellular proliferative responses to various growth factors and other environmental signals. Capable of specific binding to a cAMP response element in DNA.