Sodium/ascorbate cotransporter (PubMed:10331392). Mediates electrogenic uptake of vitamin C, with a stoichiometry of 2 Na(+) for each ascorbate (By similarity). L-ascorbate(out) + 2 Na(+)(out) = L-ascorbate(in) + 2 Na(+)(in) Highly expressed in neural, neuroendocrine, exocrine and endothelial tissues and in osteoblasts. Detected in neurons throughout the central nervous system, in meninges and choroid plexus, in the anterior pituitary, the intermediate lobe, in pancreas, adrenal cortex, gastric glands, and in the inner nuclear layer of the retina. Phosphorylated. Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.