Effector protein that participates in the suppression of macrophage apoptosis by blocking the extrinsic pathway. Recognizes the host polypyrimidine tract binding protein-associated splicing factor (PSF), which probably leads to its cleavage, diminishing the level of caspase-8 in macrophages. Interacts with human polypyrimidine tract binding protein-associated splicing factor (PSF). Is secreted into the macrophage cytoplasm. Might be secreted via a type IV pili apparatus that seems to be encoded in the same operon. Component of the Rv3654c-Rv3660c operon that is highly up-regulated during M.tuberculosis infection of macrophages.