Cytochrome P450 monooxygenase; part of the gene cluster that mediates the biosynthesis of aspergiltriene A, aspergildienes A-D and aspergilols A-D (PubMed:33480256). The bifunctional terpene synthase AuAS converts DMAPP and IPP into sesterterpenes (PubMed:33480256). The C-terminal prenyltransferase (PT) domain of AuAS catalyzes formation of GFPP, whereas the N-terminal terpene cyclase (TC) domain catalyzes the cyclization of GFPP into 5 distinct sesterterpenes: aspergiltriene A, aspergildiene A, aspergildiene B, aspergildiene C and aspergildiene D (PubMed:33480256). The cytochrome P450 monooxygenase AP450 then hydroxylates the aspergildienes A, B, C and D to yield the corresponding sesterterpene alcohols, aspergilols A-D (PubMed:33480256). Secondary metabolite biosynthesis; terpenoid biosynthesis. Aspergilol A shows a weak cytotoxicity toward MCF-7, MDA-MB231, and HepG2 cancer cells lines, with an IC(50) value ranging from 21.21 to 48.76 uM; whereas aspergilol B only shows a weak cytotoxicity against MCF-7 cells, with an IC(50) value of 27.41 uM (PubMed:33480256). None of the aspergilols have antifungal or antibacterial activities (PubMed:33480256). Belongs to the cytochrome P450 family.