Pleiotropic ABC efflux transporter involved in the modulation susceptibility to itraconazole. ATP + H2O + itraconazole(in) = ADP + H(+) + itraconazole(out) + phosphate Is slightly over-expressed in strain TIMM20092, and azole-resistant strain isolated in Switzerland. Belongs to the ABC transporter superfamily. ABCB family. Multidrug resistance exporter (TC 3.A.1.201) subfamily.