Represses thailandamide production. No production of thailandamide antibiotic. When the promoter region is disrupted (121 bases before the start codon) thailandamide production increases (PubMed:20853892). In 2 other promoter disruption mutants (617 and 624 bases before the start codon) this bacterium no longer inhibits growth of Salmonella in an overlay assay, suggesting no thailandamide is produced (PubMed:29914944). Thailandamide is a polyketide that is toxic to human cell lines but also has antibacterial activity on E.coli, S.typhimurium and S.aureus. It probably acts on acetyl-CoA carboxylase in the fatty acid synthesis pathway, which is rarely found to be an antibiotic target. These data suggest it might be a good starting point for engineering of novel antibiotics. Belongs to the autoinducer-regulated transcriptional regulatory protein family.