Guanylate cyclase involved in the production of the second messenger cGMP (By similarity). Unlike other guanylate cyclases expressed in ASE neurons, may not play a role in chemotaxis responses toward salt ions in ASEL (ASE left) sensory neurons (PubMed:19523832). GTP = 3',5'-cyclic GMP + diphosphate Expressed asymmetrically in ASE left (ASEL) sensory neuron (PubMed:16099833, PubMed:16547101). Expressed in excretory canal cell (PubMed:16547101). Expressed in both ASEL and ASER neurons throughout late embryonic and early larval stages. The protein kinase domain is predicted to be catalytically inactive. Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.