Negatively regulates myogenesis and skeletal muscle regeneration via its association with ITGB1 (PubMed:34427057). Modulates ITGB1 activation by decreasing ITGB1-LAMB1 interaction and inhibiting ITGB1-mediated intracellular signaling during myogenesis (PubMed:34427057). Interacts with ITGB1. Expressed in skeletal muscle and adipose tissue. Up-regulated during myoblast differentiation. Belongs to the TMEM182 family.