Protein kinase required for the cell cycle where it is involved in mitotic exit. A component of the fear (CDC14 early anaphase release) network which promotes CDC14 release from the nucleolus during early anaphase. Phosphorylates SCC1/MCD1 and NET1. ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein] ATP + L-threonyl-[protein] = ADP + H(+) + O-phospho-L-threonyl-[protein] Interacts with CDC48; the interaction is likely to result in CDC5 degradation. Present with 1480 molecules/cell in log phase SD medium. Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. CDC5/Polo subfamily.