When injected intracranially in mice, induces a series of symptoms such as quivering, climbing, scratching, barrel rolling and paralysis of limbs. Unexpectedly, no effect is observed on ionic currents when tested on locust DUM neuron. Expressed by the venom duct. The presence of a 'disulfide through disulfide knot' structurally defines this protein as a knottin. The cysteine framework is VI/VII (C-C-CC-C-C). Belongs to the conotoxin O1 superfamily.