Induces apoptosis in cooperation with SIAH1A. Acts as a mediator between p53/TP53 and BAX in a neuronal death pathway that is activated by DNA damage. Acts synergistically with TRAF2 and inhibits TNF induced apoptosis through activation of NF-kappa-B (By similarity). Homodimer. Interacts with SIAH1A and SIAH2. Interacts with TRAF2 (By similarity). The SCAN domain enables PEG3 homo- or heterodimerization to control gene expression in a combinatorial fashion. Belongs to the krueppel C2H2-type zinc-finger protein family.