This PTPase activity may directly link growth factor receptors and other signaling proteins through protein-tyrosine phosphorylation. The SH2 regions may interact with other cellular components to modulate its own phosphatase activity against interacting substrates (By similarity). May play a positive role during the stages of erythroid cell proliferation (PubMed:8921851). H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate Expressed in embryonic fibroblast, hematopoietic, erythroid, myeloid and lymphoid cells. Phosphorylated by tyrosine-protein kinases. Belongs to the protein-tyrosine phosphatase family. Non-receptor class 2 subfamily.