an aliphatic amine + H2O + O2 = an aldehyde + H2O2 + NH4(+) Binds 1 copper ion per subunit. Can also use zinc ion as cofactor (PubMed:10933787). Contains 1 topaquinone per subunit. Binds 1 Mn(2+) ion per subunit. Homodimer. By methylamine. Topaquinone (TPQ) is generated by copper-dependent autoxidation of a specific tyrosyl residue. Belongs to the copper/topaquinone oxidase family.