Mediates sodium- and chloride-dependent transport of taurine (PubMed:11118543). Can also mediate transport of beta-alanine, hypotaurine and gamma-aminobutyric acid (GABA) (By similarity). 4-aminobutanoate(out) + chloride(out) + 2 Na(+)(out) = 4-aminobutanoate(in) + chloride(in) + 2 Na(+)(in) chloride(out) + 2 Na(+)(out) + taurine(out) = chloride(in) + 2 Na(+)(in) + taurine(in) beta-alanine(out) + chloride(out) + 2 Na(+)(out) = beta-alanine(in) + chloride(in) + 2 Na(+)(in) chloride(out) + hypotaurine(out) + 2 Na(+)(out) = chloride(in) + hypotaurine(in) + 2 Na(+)(in) Taurine transport activity is inhibited by L-alanine, guanidinoethane sulfonate, homotaurine and phorbol 12-myristate 13-acetate (PubMed:11118543). Taurine transport activity is stimulated by hypertonic stress (PubMed:11118543). Taurine transport activity is down-regulated upon Ser-322 phosphorylation. Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. SLC6A6 subfamily.