Involved in the synthesis of chondramides. Activates R-beta-tyrosine and probably phenylalanine. Binds 2 phosphopantetheines covalently. Two module-bearing peptide synthase. Each module incorporates one amino acid into the peptide product and can be further subdivided into domains responsible for substrate adenylation, condensation and epimerization (Probable). Chondramides are secondary metabolites with antifungal and cytotoxic activity. They are non-ribosomally produced depsipeptides consisting of a polyketide chain and 3 amino acids (alanine, N-methyltryptophan and beta-tyrosine or alpha-methoxy-beta-tyrosine). Belongs to the ATP-dependent AMP-binding enzyme family.