Forms pores that allow passive diffusion of small molecules across the outer membrane (Probable). Plays a role in virulence (PubMed:8359885). Homotrimer. Forms mixed heterotrimers with OmpF and with PhoE; other mixed heterotrimers are also probable. Unlike E.coli, constitutively expressed at low and high osmolarity (0.3M NaCl) (at protein level). Expression is under the control of OmpR-EnvZ two-component system; still expressed at very low levels in high osmolarity in the absence of ompR-envZ (at protein elevel). Lowered rate of infection of HeLa cells. Bacteria are seriously impaired in their ability to spread from host cell to host cell. This strain has 2 ompC genes; it is not clear which one has been detected in cell outer membranes nor deleted in PubMed:8359885. Belongs to the Gram-negative porin family.