May play a role in microtubule deacetylation by negatively regulating the SIRT2 deacetylase activity toward alpha-tubulin and thereby participate in the control of cell cycle progression and genomic stability. Interacts with alpha-tubulin. Interacts with SIRT2. Also localizes to microtubules. Expressed in both Sertoli and germ cells as well as interstitial area of the testis (at protein level). Up-regulated by cadmium in testis (at protein level) (PubMed:28295929). Up-regulated by curcumin (PubMed:28145533). Ubiquitinated and degraded by the proteasome. Belongs to the BEX family.