ATPase component of the INO80 complex which remodels chromatin by shifting nucleosomes and is involved in DNA repair. Its ability to induce transcription of some phosphate-responsive genes is modulated by inositol polyphosphates. The INO80 complex is involved in DNA repair by associating with 'Ser-129' phosphorylated H2A histones as a response to DNA damage. ATP + H2O = ADP + H(+) + phosphate Component of the chromatin-remodeling INO80 complex, at least composed of ARP4, ARP5, ARP8, RVB1, RVB2, TAF14, NHP10, IES1, IES3, IES4, IES6, ACT1, IES2, IES5 and INO80. The DBINO region is involved in binding to DNA. Belongs to the SNF2/RAD54 helicase family.