Serine protease with cytotoxic effect. Disrupts actin cytoskeleton resulting cell detachment in vitro. The cleaved C-terminal fragment (autotransporter domain) is localized in the outer membrane. The signal peptide, cleaved at the inner membrane, guides the autotransporter protein to the periplasmic space. Then, insertion of the C-terminal translocator domain in the outer membrane forms a hydrophilic pore for the translocation of the passenger domain to the bacterial cell surface, with subsequent cleavage (By similarity). Cleaved to release the mature protein from the outer membrane. Encoded on an unnamed 94 kb plasmid.