Confers susceptibility to the fungus Cochliobolus victoriae by conditioning victorin-dependent (victorin is a toxin synthesized by C.victoriae) induction of defense-associated proteins. Repressed by silencing mediated by polycomb group (PcG) protein complex containing EMF1 and EMF2. The LRR repeats probably act as specificity determinant of pathogen recognition. Belongs to the disease resistance NB-LRR family. RPP8/HRT subfamily. Has been shown to be a pseudogene in cv. Columbia (AC O04093) due to a stop codon at position 117 and a naturally occurring frameshift at position 846 in this strain. The sequence shown is from strain cv. Cl-0. Functional and comparative genomics of disease resistance gene homologs