Serine/threonine-protein acetyltransferase translocated into infected cells, which impairs host microtubule network and host immunity by mediating acetylation of target proteins (PubMed:20636323, PubMed:22319451, PubMed:24204266, PubMed:27525589). Blocks secretion in host cells by mediating acetylation of host tubulin, thereby impairing host microbubule network (PubMed:22319451). Impairs host cell immunity by mediating acetylation of host TIFY/JAZ transcription repressors (Arabidopsis thaliana TIFY10B/JAZ2, TIFY11A/JAZ5, TIFY11B/JAZ6, TIFY5A/JAZ8, TIFY9/JAZ10 and TIFY3B/JAZ12), thereby activating host jasmonate signaling (PubMed:24204266, PubMed:27525589). acetyl-CoA + L-threonyl-[protein] = CoA + O-acetyl-L-threonyl-[protein] acetyl-CoA + L-seryl-[protein] = CoA + O-acetyl-L-seryl-[protein] acetyl-CoA + L-lysyl-[protein] = CoA + H(+) + N(6)-acetyl-L-lysyl-[protein] 1D-myo-inositol hexakisphosphate activates protein-acetyltransferase activity via an allosteric mechanism: 1D-myo-inositol hexakisphosphate-binding induces a conformational rearrangement that stimulates the interaction with acetyl-CoA (PubMed:27525589). Acetyltransferase activity is activated by phytic acid (PubMed:22319451). Interacts with host plant JAZ proteins (e.g. Glycine max JAZ1 and Arabidospis thaliana TIFY10B/JAZ2, TIFY11A/JAZ5, TIFY11B/JAZ6, TIFY5A/JAZ8 and TIFY3B/JAZ12) and trigger their degradation. Secreted via type III secretion system (TTSS). Autoacetylated at Lys-289; while autoacetylation at Lys-289 is required for virulence function to some extent, it is not essential. Belongs to the acetyltransferase YopJ family.