Plays a role in cardioprotection by reducing cardiac hypertrophy and perivascular fibrosis in a GPER1-dependent manner. Transports the calcitonin gene-related peptide type 1 receptor (CALCRL) to the plasma membrane. Acts as a receptor for adrenomedullin (AM) together with CALCRL. Interacts with GPER1 (By similarity). Heterodimer of CALCRL and RAMP3. Expressed predominantly in the testis, embryonic and adult brain and in kidney. Belongs to the RAMP family.