Putative metalloproteinase that plays a role in left-right patterning process. Binds 1 zinc ion per subunit. Specifically expressed in ciliated left-right organizer. Strong levels in the ventral node from the early bud to the four-somite stage. Expression is enriched in the perinodal crown cells and become asymmetric at the three-somite stage. Belongs to the peptidase M8 family.