Shows cytotoxic activity against Ehrlich ascites carcinoma (EAC) model in mice. Also shows effect on apoptotic features such as nuclear fragmentation, caspase activity, pro- and anti-apoptotic protein levels on treated EAC cells. Increased levels of antioxidant enzymes and cytokine levels observed in toxin-treated EAC mice. Cardiotoxic towards guinea pig auricle. Has no cytotoxicity towards macrophages in vivo in EAC bearing mice or in vitro in normal human lymphocytes. Monomer in solution; Homodimer and oligomer in the presence of negatively charged lipids forming a pore with a size ranging between 20 and 30 Angstroms. Expressed by the venom gland. LD(50) is 4 mg/kg by intraperitoneal injection in mice. Belongs to the snake three-finger toxin family. Short-chain subfamily. Type IA cytotoxin sub-subfamily.