D-galactose specific lectin. Binds in decreasing order of affinity: melibiose, N-acetyllactosamine, D-galacturonic acid, D-galactose, methyl-alpha-D-galactoside, D-galactose, methyl-alpha-D-galactopyranoside, methyl-beta-D-galactopyranoside and lactose. Binds also the glycoproteins globotriose, asialofetuin and mucin. Possesses glycan-dependent cytotoxic activity against Burkitt's lymphoma Raji cells and erythroleukemia K562 cells. Has calcium-independent hemagglutinating activity towards human erythrocytes. Hemagglutinating activity is stable over the pH range 4.0-12.0 but decreases below pH 3. Hemagglutinating activity is stable when incubated over the range of 20-70 degrees Celsius for 60 minutes but is almost lost after incubation for 60 minutes at 80 degrees Celsius. Homodimer. N-glycosylated.