Transcription factor (PubMed:26963674). Binds to the regulatory elements of genes that contain the sequence motif 5'-TTGTTTCT-3' (PubMed:26963674). Involved in regulating intestinal transcription of vitellogenin vit-2, acting in concert with transcription factors elt-2, mab-3 and daf-16, and also the TGF-beta/Sma/Mab pathway (PubMed:26963674). Functions downstream of the insulin/IGF-1-like signaling (IIS) mediated pathway, in regeneration of axons after injury and in short-term memory, perhaps acting in neurons, and in modulation of longevity, perhaps acting non-neuronally (PubMed:26675724). Plays a role in the modulation of endoplasmic reticulum (ER) homeostasis during chemical and pathogen stress, including exposure to the Gram-negative bacterium P.aeruginosa (PubMed:30287474). Expressed in mechanosensory neurons. Expressed in neurons and intestinal cells in L2 stage larvae. RNAi-mediated knockdown severely impairs axon regeneration in a daf-2 mutant background, in a daf-16-dependent-manner (PubMed:26675724). Impairs short-term associative memory in a daf-2 mutant background in a daf-16-dependent-manner (PubMed:26675724). Reduces longevity in a daf-2 mutant background (PubMed:26675724).