Protein tyrosine phosphatase which stimulates progression from G1 into S phase during mitosis. May play a role in the development and maintenance of differentiating epithelial tissues (By similarity). H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate Inhibited by sodium orthovanadate and pentamidine. Homotrimer. Interacts with ATF5 and tubulin (By similarity). And mitotic spindle. Farnesylated. Farnesylation is required for membrane targeting (By similarity). Belongs to the protein-tyrosine phosphatase family.