Required for the processing of the 27S pre-rRNA. Specifically interacts with EBV EBNA1. The EBNA1-EBP2 interaction is important for the stable segregation of EBV episomes during cell division (PubMed:10074103). Interacts with WDR46. Associated with the nucleolus in an RNA-dependent manner. Ubiquitous. Belongs to the EBP2 family.