Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells (By similarity). As cell intercalation proceeds, a row of stigmatophore cells surrounding the spiracular chamber show expression of Cad86C. Expression is regulated by the Abd-B cascade, requiring sal. Expressed in a broad region of the morphogenetic furrow and in clusters of cells posterior to the morphogenetic furrow. Weakly expressed in the epithelium of wing imaginal disks. In eye imaginal disk cells within the morphogenetic furrow, expression is localized to the apical region. By hedgehog (hh) and dpp signal transduction in the morphogenetic furrow. Three calcium ions are usually bound at the interface of each cadherin domain and rigidify the connections, imparting a strong curvature to the full-length ectodomain. Truncated C-terminus.