Transcription factor that governs genes involved in reductive and siderophore-mediated iron acquisition, and carbon metabolism (PubMed:21062375). Suppresses the expression of sreA and induces hapX to stimulate expression of genes involved in both reductive iron assimilation and siderophore-mediated iron uptake which is essential for the maximal virulence (PubMed:21062375). Regulates also genes involved in gluconeogenesis (PubMed:21062375). Expressed constitutively with similar lebels in swollen conidia, germlings and hyphae (PubMed:21062375). Leads to attenuated virulence in mouse models of haematogenously disseminated and invasive pulmonary aspergillosis (PubMed:21062375). Results in increased expression of sreA and reduced expression of hapX iron acquisition transcription factors (PubMed:21062375). Impairs also gluconeogenesis (PubMed:21062375).