May be involved in gene regulation within neural lineage cells potentially by direct DNA binding or by binding to other transcription factors. Expressed mainly in the central nervous. Low level of expression in other tissues including thymus. A chromosomal aberration involving LMO1 may be a cause of a form of T-cell acute lymphoblastic leukemia (T-ALL). Translocation t(11,14)(p15;q11) with TCRD. Extended N-terminus.