Involved in the immune response to bacterial infection. Up-regulated following injection with the Gram-negative bacterium E.coli. Up-regulation increases between 1 and 12 hours after the injection, then decreases between 12 and 48 hours, and then increases again at 72 hours. Belongs to the GILT family. Lacks the conserved active site CXXC motif that is essential for thiol reductase activity. Its enzyme activity is therefore unsure.