Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner (By similarity). Homodimer, and heterodimer with other family members. Expressed in brain, gill, heart, intestine, kidney, liver, ovary, skeletal muscle, spleen and testis. Expressed throughout development. Repressed under stress conditions such as netting. Belongs to the 14-3-3 family.