H2A.Z-specific chromatin binding protein which plays an important role in the neural crest cell differentiation and/or migration during early development and is essential for the development of the head and eye (PubMed:28645917). Acts as an adapter between distinct nucleosome components (H3K36me3 or H2A.Z) and chromatin-modifying complexes, contributing to the regulation of the levels of histone acetylation at actively transcribed genes (By similarity). Embryos exhibit lack of retinal tissue combined with a reduced head size. Defects in neural crest stem cell migration and differentiation seen.