Probably acetylates spermine to N(1)-acetylspermine. acetyl-CoA + an alkane-alpha,omega-diamine = an N-acetylalkane-alpha,omega-diamine + CoA + H(+) acetyl-CoA + spermine = CoA + H(+) + N(1)-acetylspermine Amine and polyamine degradation; spermine degradation. Expression is strongly induced by spermine, but not by agmatine, putrescine or spermidine. Belongs to the acetyltransferase family.