Participates in cytokinesis (PubMed:19799413). Necessary for microtubules and mitotic spindle organization (PubMed:24867236). Involved in primary cilium formation (PubMed:24867236). Interacts with DCTN1. Expressed in brain, lung, skeletal muscle, kidney, pancreas, testis and ovary. Depletion of CEP126 by siRNA results in an increase in cytokinesis aberrant cells.