Catalyzes the deacetylation of acetylated polyamines such as N-acetylputrescine, N-acetylcadaverine, N(1)-acetylspermine and N(1)-acetylspermidine. Plays an important role in the metabolism of acetylated polyamines in P.aeruginosa. Is involved in the degradation pathways of N-acetylputrescine and N-acetylcadaverine, that allow P.aeruginosa to utilize these acetylpolyamines as a carbon source under glucose starvation. In vitro, can also hydrolyze artificial trifluoroacetylated and acetylated lysine-derivatives. H2O + N-acetylputrescine = acetate + putrescine H2O + N-acetylcadaverine = acetate + cadaverine H2O + N(1)-acetylspermine = acetate + spermine H2O + N(1)-acetylspermidine = acetate + spermidine Binds 1 zinc ion per subunit. Amine and polyamine metabolism. Homodimer. By exogenous acetylputrescine and agmatine, but not by putrescine. Cells lacking this gene are unable to use N-acetylcadaverine as sole carbon source for growth, and display an elongated lag-phase of approximately 6 hours before growing on N-acetylputrescine. The deletion mutant strain exhibits only marginal changes in biofilm biomass in comparison to the wild-type. Belongs to the histone deacetylase family.