Transcriptional activator (By similarity). Binds a GC box motif. Could play a role in B-cell growth and development. Interacts with ZZEF1. Highly expressed in placenta followed by spleen, thymus, prostate, testis, small intestine and colon. Weakly expressed in pancreas, lung, liver, heart and skeletal muscle. Also expressed in fetal brain, spleen and thymus. The acidic N-terminal part may favor interaction with the basic domain of transcription factors. The 9aaTAD motif is a transactivation domain present in a large number of yeast and animal transcription factors. In KLF6, the motif is inactive. The disease is caused by variants affecting the gene represented in this entry. The disease is caused by variants affecting the gene represented in this entry. Belongs to the krueppel C2H2-type zinc-finger protein family. Extended N-terminus. Extended N-terminus.