Regulates coat complex coatomer protein I (COPI)-independent Golgi-endoplasmic reticulum transport by recruiting the dynein-dynactin motor complex. Interacts with RAB6A. Interacts (via C-terminus) with RAB6B (GTP-bound); the interaction is direct. Interacts with CLIP-115 and KIFC2 (By similarity). (Microbial infection) Interacts with human cytomegalovirus/HHV-5 protein UL32. Expressed in the brain, heart and skeletal muscle. Due to intron retention. Due to intron retention. Belongs to the BicD family.