Enhances the promotion of guanine-nucleotide exchange by PSCD2 on ARF6 in a concentration-dependent manner. Interacts with guanine-nucleotide exchange factors PSCD1, PSCD2, PSCD3 and PSCD4 (By similarity). Interacts (via C-terminus) with cytohesin-2 CYTH2 (PubMed:22085542). Translocated with PSCD2 to the plasma membrane upon epidermal growth factor (EGF) stimulation. It is uncertain whether Met-1 or Met-29 is the initiator.