Cation/chloride cotransporter that may play a role in the control of keratinocyte proliferation. Ubiquitous with very low level in normal skin. SLC12A8 has been identified as a possible susceptibility gene for psoriasis mapped to chromosome 3q21 (PSORS5). Belongs to the SLC12A transporter family. Truncated N-terminus. Truncated N-terminus. Extended N-terminus. Extended N-terminus.