Via its association with the multisubunit axonemal dynein complex, is potentially involved in the regulation of cilia function. May act as a cell cycle regulator. Part of the multisubunit axonemal dynein complex formed at least of two heavy chains and a number of intermediate and light chains. Associates with tubulin. Interacts with microtubule. Colocalizes with microtubules in interphase. Ubiquitinated. Ubiquitination leads to its degradation through the 26S proteasome. Ubiquitin-proteasome-mediated DNAI7 degradation occurs in mitosis. Belongs to the DNAI7 family.