Involved in synaptic transmission (By similarity). Kinesin is a microtubule-associated force-producing protein that may play a role in organelle transport. Mediates dendritic trafficking of mRNAs (PubMed:19608740). Required for anterograde axonal transportation of MAPK8IP3/JIP3 which is essential for MAPK8IP3/JIP3 function in axon elongation (By similarity). Oligomer composed of two heavy chains and two light chains (PubMed:15286375). Interacts with GRIP1 (PubMed:11986669). Interacts with KLC3 and TRAK1 (By similarity). Interacts with ZFYVE27 (PubMed:21976701). Abundant in distal regions of dendrites. Composed of three structural domains: a large globular N-terminal domain which is responsible for the motor activity of kinesin (it hydrolyzes ATP and binds microtubule), a central alpha-helical coiled coil domain that mediates the heavy chain dimerization; and a small globular C-terminal domain which interacts with other proteins (such as the kinesin light chains), vesicles and membranous organelles. Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. Kinesin subfamily. Chimeric cDNA. The C-terminus (up to position 300) corresponds to KIF5C sequence.