Plays a role in spermiogenesis (PubMed:26501274). Involved in the elongation of flagella and the formation of sperm heads (PubMed:26501274). Expressed in testis, brain, thymus and lung (PubMed:26501274). Male mice are infertile despite regular copulation. Display shortened sperm tails and malformed sperm heads and motionless spermatozoa (PubMed:26501274). The 9+2 structure of the axoneme seems to be intact (PubMed:26501274). Spermatozoa are able to activate oocytes when used in intracytoplasmic sperm injection (ICSI) and these embryos are able to develop to term (PubMed:26501274).