Peptide antibiotic with selective activity against Mycobacterium species (M.smegmatis, MIC=3.13 ug/ml and M.tuberculosis, MIC=0.39 ug/ml). it is plausible that the target of lariatins lies within the cell wall in mycobacteria. Peptide antibiotic with selective activity against Mycobacterium species (M.smegmatis, MIC=6.25 ug/ml). Is composed of a ring composed by 8 residues, and a tail of 10 or 12 residues (Probable). The peptide is threaded when the C-terminal tail is inserted throught the isopeptide-bonded ring (Probable). The linear precursor LarA is probably cleaved by the putative peptidase LarD, generating linear 18-residue Lariatin-A or 20-residue Lariatin-B. These linear peptides are probably cross-linked by LarB. Finally, lariatins A and B may be exported by ABC transporter LarE.