Acts as a membrane anchor, bringing other regulators of programmed cell death (PCD) to the plasma membrane. Negatively regulates hypersensitive cell death. Interacts (via N- and C-terminal) with MIEL1 and LSD1 (via N-terminus). Up-regulated by Pseudomonas syringae avrRpt2 and fumonisin B1 (FB1). The LITAF domain is stabilized by a bound zinc ion (By similarity). The LITAF amphipathic helix region (68-90) is necessary for plasma membrane localization. Both N-terminal (1-47) and C-terminal (114-134) domains are sufficient for the interaction with MIEL1 or with the N-terminal domain of LSD1. The LITAF domain (48-113) is not involved in the interaction with LSD1. Belongs to the CDIP1/LITAF family.