Cytotoxin and helminthotoxin with low-efficiency ribonuclease activity. Possesses a wide variety of biological activities. Exhibits antibacterial activity (By similarity). Interacts with bacterial lipopolysaccharide (LPS) and lipoteichoic acid (LTA). In vitro interacts with phospholipid bilayers. Located in the matrix of eosinophil large specific granule, which are released following activation by an immune stimulus. Belongs to the pancreatic ribonuclease family.