Ion channel inhibitor that inhibits the increase in intracellular calcium upon depolarization in DRG neurons. In vivo, both intraperitoneal and intracranial injections into mice induce hyperactivity. Expressed by the venom duct. The presence of a 'disulfide through disulfide knot' structurally defines this protein as a knottin. The cysteine framework is VI/VII (C-C-CC-C-C). Belongs to the conotoxin O1 superfamily.