Component of the ribosome assembly machinery. Nuclear paralog of the ribosomal protein P0, it binds pre-60S subunits at an early stage of assembly in the nucleolus, and is replaced by P0 in cytoplasmic pre-60S subunits and mature 80S ribosomes. Associates with the pre-60S ribosomal particle. Shuttles between the nucleus and the cytoplasm. Present with 18200 molecules/cell in log phase SD medium. Belongs to the universal ribosomal protein uL10 family.