Required for cytoplasm to vacuole transport (Cvt) and autophagy as a part of the autophagy-specific vps34 PI3-kinase complex I. This complex is essential to recruit the atg8-phosphatidylinositol conjugate and the atg12-atg5 conjugate to the preautophagosomal structure. Atg14 mediates the specific binding of the vps34 PI3-kinase complex I to the preautophagosomal structure (PAS) (By similarity). Component of the autophagy-specific vps34 PI3-kinase complex I composed of ppk19/vps15, atg6, pik3/vps34 and atg14 (By similarity). Interacts with atg6. Coiled-Coils at the N-terminal half are essential for autophagy. Belongs to the ATG14 family.