Toxic component of a type II toxin-antitoxin (TA) system. An RNase (By similarity). Its cognate antitoxin is VapB40. Physically interacts with non-cognate antitoxin VapB27 and cognate antitoxin VapB40. Belongs to the PINc/VapC protein family. Bioinformatics programs predicts this could have a signal sequence.