Required for neuron survival through the modulation of MAPK pathways (PubMed:12941464). Involved in the regulation of hypothalamic GNRH secretion and the control of puberty. Homotrimer. Binds to PKC beta-1. Widely expressed in brain (PubMed:18547942). High expression is observed in telencephalic and diencephalic glutamatergic neurons, while no expression is found in GABAergic and GNRH neurons (PubMed:18547942).