Interacts with NEDD4 (By similarity). Binds to the WW domain of YAP1, WWP1 and WWP2. Interacts with WWOX. Expressed in most tissues but at significantly lower levels in placenta, lung, liver, and kidney. The PPxY motif 2 mediates interaction with WWOX. Both PPxY motifs mediate interaction with NEDD4 (By similarity).