Component of the propane 2-monooxygenase multicomponent enzyme system which is involved in the degradation of propane via the O2-dependent hydroxylation of propane. Also able to catalyze the oxidation the water contaminant N-nitrosodimethylamine (NDMA). H(+) + NADH + O2 + propane = H2O + NAD(+) + propan-2-ol Binds 2 Fe(2+) ions per subunit. The propane 2-monooxygenase multicomponent enzyme system is composed of an electron transfer component and a monooxygenase component interacting with the effector protein PrmD. The electron transfer component is composed of a reductase (PrmB), and the monooxygenase component is formed by a large subunit (PrmA) and a small subunit (PrmC) (PubMed:17873074). Probably requires the presence of the chaperonin-like protein PrmG to ensure a productive folding, resulting of a soluble PrmA, which leads to the active form of PrmABCD (PubMed:23171424). By propane. Cells lacking this gene are unable to grow on propane and to degrade N-nitrosodimethylamine (NDMA). Belongs to the TmoA/XamoA family.