Involved in the uptake of the purine bases hypoxanthine and guanine. May work at purine concentrations higher than 100 uM. Expression is regulated by the purR regulon. Down-regulated by adenine and up-regulated by guanosine. Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.