Positive regulator of FPS1 glycerol channel required for the glycerol efflux. As a component of the RNA polymerase II holoenzyme, is required for SSN8 destruction in response to oxidative stress but not heat shock. Required for cell survival in response to heat shock independent of SSN8. Component of the RNA polymerase II holoenzyme. Interacts with RPO21 and SSN8. Displays diffuse cytoplasmic localization, but very rapidly aggregates into punctate spots that appear near the cell surface in response to hypo-osmotic shock. Phosphorylated in response to various stresses. stress-induced phosphorylation is partially dependent on HOG1. Belongs to the RGC1 family.