During embryogenesis, necessary for dendritic and axonal organization and growth at the neuromuscular junction through the regulation of the synaptic microtubule cytoskeleton (PubMed:10839355, PubMed:10839356, PubMed:11733059). Microtubule hairpin loops are found within a small subset of synaptic boutons at the neuromuscular synapse, these loops are stabilized by Futsch (PubMed:10839355, PubMed:10839356, PubMed:11733059). Loop morphology and dynamics suggest that rearrangement of these microtubule-based loops is a critical component of the process of bouton division and for subsequent nerve-terminal growth and branching (PubMed:10839355, PubMed:10839356, PubMed:11733059). Translation is repressed by Fmr1 (PubMed:10839355, PubMed:10839356, PubMed:11733059). Together with Ringer, required for neuromuscular junction (NMJ) bouton growth by regulating synaptic microtubules (PubMed:31156389). Heterodimer of a heavy and a light chain (PubMed:18419581). Interacts with Fmr1 (PubMed:11733059). Found in a complex with tubulin and Futsch (PubMed:31156389). Microtubule-associated. Neuronal cells within the PNS and CNS. All stages. Several minor light chains can be created with markedly different pIs. Phosphorylated by SGG/GSK3. Phosphorylated by LRRK2 at the presynapse of neuromuscular junctions, which negatively regulates the activity controlling synaptic differentiation. Flies lacking both Ringer and Futsch display a significant reduction in microtubule loops at the neuromuscular junctions (NMJ) and reduced acetylated-tubulin levels. 'Futsch' means 'gone' in German.