Repressor of jasmonate responses. Jasmonoyl-isoleucine (JA-Ile) specifically promotes COI1-TIFY10A/JAZ1 interaction. Interacts with COI1 and inositol pentakisphosphate to form a high-affinity jasmonates coreceptor. Homo- and heterodimer. Interacts with TIFY10B/JAZ2, TIFY6B/JAZ3, TIFY6A/JAZ4, TIFY11A/JAZ5, TIFY11B/JAZ6, TIFY5A/JAZ8, TIFY7/JAZ9, TIFY9/JAZ10, TIFY3A/JAZ11 and TIFY3B/JAZ12. Interacts with COI1, MYC2, MYC3, MYC4, MYB21 and MYB24. Interacts (via tify domain) with AFPH2/NINJA. (Microbial infection) Interacts with the pathogenic Pseudomonas syringae HopZ1a protein. (Microbial infection) Interacts with Pseudomonas syringae HopZ1a at the plasma membrane and in the nucleus. A number of isoforms are produced. According to EST sequences. Srtongly expressed in root tips. Up-regulated by jasmonate, wounding and herbivory. (Microbial infection) Triggered to degradation by the pathogenic Pseudomonas syringae HopZ1a protein in a COI1-dependent manner, thereby activating host jasmonate signaling. The jas domain (202-227) is necessary and sufficient for interaction with COI1 and is required for TIFY 10A/JAI1 instability in response to jasmonate (PubMed:17675405, PubMed:18547396). The jas domain (202-227) is required for interaction with Pseudomonas syringae HopZ1a (By similarity). (Microbial infection) Acetylated by Pseudomonas syringae HopZ1a. Ubiquitinated. Targeted for degradation by the SCF(COI1) E3 ubiquitin ligase-proteasome pathway during jasmonate signaling. Belongs to the TIFY/JAZ family.