Pump for glutathione S-conjugates. Mediates the transport of S-conjugates such as GSH, S-(2,4-dinitrophenyl)-glutathione (DNP-GS), GSSG, cyanidin 3-glucoside-GS (C3G-GS) and metolachlor-GS (MOC-GS), glucuronides such as 17-beta-estradiol 17-(beta-D-glucuronide) (E(2)17betaG), and of the chlorophyll catabolite such as B.napus nonfluorescent chlorophyll catabolite (Bn-NCC-1). ATP + H2O + xenobioticSide 1 = ADP + phosphate + xenobioticSide 2. Reciprocal promotion of DNP-GS and E(2)17betaG uptake. E(2)17betaG uptake is also stimulated by GSH and S-methyl-glutathione (S-methyl-GS), and, to a lower extent, by GSSG and C3G-GS. Metolachlor-GS and decyl-GS slightly inhibit E(2)17betaG uptake. Interacts with FKBP42/TWD1 and probably with calmodulin (CaM). Tonoplast. Ubiquitous, at low levels. By 1-chloro-2,4-dinitrobenzene (CDNB). Belongs to the ABC transporter superfamily. ABCC family. Conjugate transporter (TC 3.A.1.208) subfamily.