May be involved in cell migration, cartilage development and in linking signal transduction pathways to the cytoskeleton. May promote apoptosis, via its cleavage by caspase-3. Cytoplasm, cytoskeleton. Binds to actin filaments and interacts with phosphotyrosine-containing proteins. Proteolytically cleaved by caspase-3 during apoptosis. Tyrosine phosphorylated. Belongs to the PTEN phosphatase protein family.