Secretogranin-1 is a neuroendocrine secretory granule protein, which may be the precursor for other biologically active peptides. Neuroendocrine and endocrine secretory granules. Expressed in the brain, adrenal medulla and anterior pituitary. In the brain, localized to the hippocampal formation, the endocrine hypothalamus, the olfactory system, and in anatomically distinct structures in the pons-medulla. First expressed in the brain around embryonic days 13-14, and peaks by postnatal day 20. Extensively processed in glucagonoma tissue by limited proteolysis at conserved basic residues. Alternative processing are seen in different tissues. The proglucagon-converting enzymes present in transformed alpha-cells are likely candidates to be involved in tissue-specific processing. Sulfated and phosphorylated CCB peptide long form. Sulfated or phosphorylated CCB peptide long form. CCB peptide long form without any modifications. Sulfated and phosphorylated CCB peptide short form. Sulfated or phosphorylated CCB peptide short form. CCB peptide short form without any modifications. Belongs to the chromogranin/secretogranin protein family.