Essential for gene silencing: has a role in the structure of silenced chromatin. Plays a role in the developing brain. Detected mainly in subsets of neuronal cells of the brain. In the 17.5 dpc embryo, mainly expressed in the olfactory bulb and cerebral cortex. Postnatally, additionally expressed in the cerebellar cortex, most strongly in the hippocampus. Expressed throughout development. Citrullinated by PADI4. Belongs to the SAS10 family.