One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA. Part of the 30S ribosomal subunit (PubMed:30126986). Contacts proteins S9 and S11 (By similarity). Interacts with VmlR (PubMed:30126986). Belongs to the universal ribosomal protein uS7 family.