Palmitoyltransferase specific for VAC8. Palmitoylates VAC8 at one or more of its N-terminal cysteine residues, which is required for its proper membrane localization. hexadecanoyl-CoA + L-cysteinyl-[protein] = CoA + S-hexadecanoyl-L-cysteinyl-[protein] The DHHC domain is required for palmitoyltransferase activity. Autopalmitoylated. Present with 2133 molecules/cell in log phase SD medium. Belongs to the DHHC palmitoyltransferase family. PFA3 subfamily.