Localizes primarily in the outer and inner layers of the spore wall and on the external wall surfaces. In the mouse lung spreaded with spores, located in spore walls along the outside surface of the outer wall and in the intercellular space surrounding spores, slowly diffusing to the surrounding tissues of mouse granuloma. Expressed in the mycelium (at protein level). Causes an allergic reaction in human. Natural and recombinant protein binds to IgE of patients allergic to toxic black mold fungus.