Hydrolyzes adenosine 5'-monophosphoramidate substrates such as AMP-morpholidate, AMP-N-alanine methyl ester, AMP-alpha-acetyl lysine methyl ester and AMP-NH2 (PubMed:11805111). Plays a role in the regulation of kinase KIN28 function (PubMed:10958787). Essential for growth on galactose media at elevated temperatures (PubMed:11805111). adenosine 5'-phosphoramidate + H2O = AMP + NH4(+) Homodimer (By similarity). Interacts with KIN28 (PubMed:10958787). Expression is increased in response to DNA replication stress (PubMed:22842922). Expression is regulated by ZAP1 during zinc-deficiency via changes in transcription start sites (PubMed:31692084). Expression is also down-regulated during unfolded protein response (UPR) (PubMed:32475637, PubMed:33184379). Present with 5410 molecules/cell in log phase SD medium. Belongs to the HINT family. It is uncertain whether Met-1 or Met-15 is the initiator.