Together with wdr-48, binds to and stimulates the activity of the deubiquitinating enzyme usp-46, leading to deubiquitination and stabilization of the glr-1 glutamate receptor. Interacts with usp-46; the interaction increases the catalytic activity of usp-46 in the presence of wdr-48. Expressed in several neurons in the head and tail. 25% decrease in glr-1 expression in the ventral nerve cord. Changed locomotion behavior with mutants displaying decreased reversal frequencies consistent with decreased glutamergic signaling.