Metalloproteinase moojenin: snake venom metalloproteinase that cleaves both alpha- and beta-chains of fibrinogen, but not the gamma-chain. Shows a coagulant activity on bovine plasma about 3.1 fold lower than crude venom. Renders the blood incoagulable when intraperitoneally administered into mice. Induces necrosis in liver and muscle, but does not cause histological alterations in mouse lungs, kidney or heart. Binds 1 zinc ion per subunit. The fibrinogenolytic and coagulant activities of the moojenin were abolished by preincubation with EDTA, 1,10-phenanthroline and beta-mercaptoethanol. Optimum pH is 4.0. Optimum temperature is 30-40 degrees Celsius. Monomer. Expressed by the venom gland. The N-terminus (from the N-terminal region of the metalloproteinase domain) is blocked. Does not cause hemorrhage in mice with doses up to 50 g. Intraplantar injection of moojenin (50 mg) into the rat hind-paw does not cause significant edematogenic or hyperalgesic effects (PubMed:22975266). Belongs to the venom metalloproteinase (M12B) family. P-III subfamily. P-IIIb sub-subfamily.