Binds to actin and affects the structure of the cytoskeleton. At high concentrations inhibits spontaneous rabbit actin nucleation. This strongly suggests this archaea has a profilin-regulated actin system, and actin-type genes can be identified in this organism. Inhibition of rabbit actin polymerization is reduced by phosphatidylinositol-(4,5)-P2(1,2-dipalmitoyl), a soluble form of the phospholipid phosphatidylinositol, suggesting an unknown lipid might regulate actin-profilin interaction in vivo. The Loki loop (specific to some members) becomes ordered on binding to rabbit actin. It is not clear if Loki profilins 1, 2 and 3 are from the same strain. Belongs to the Asgard profilin family.