Involved in gonadal development. Interacts with LDB1 and LDB2. Expressed in the dorsal thalamus and inner nuclei of the cerebellum. Expressed in urogenital ridges of mice at 9.5 dpc. Expressed in the nervous system at 10.5 dpc. Expressed in the forelimb and hindlimb buds, the caelomic cavity at the level of the urogenital ridge, including the gonads, the pancreas and liver epithelium at 11.5 dpc. Expressed widespread throughout the CNS alar neuroepithelium from 11.5 to 14.5 dpc. Expressed in pioneer neurons of the cerebral cortex. In the telencephalic vesicles, expressed in cerebral cortex, the hippocampus, the claustrum primordium, olfactory bulb primordium and the caudal ganglionic eminence (amygdaloid complex) at 13.5 dpc. In the diencephalon, expressed in the pretectum (p1 prosomere), the dorsal thalamus (except for a thin ventral band close to the alar-basal boundary), the epithalamus, the epiphysis in prosomere p2, the supraoptic-paraventricular area, the eminentia thalami (p4 prosomere), the retrochiasmatic area and the tuberal hypothalamus at 13.5 dpc. In the mesencephalon, expressed in the tectum, the walls of the hindbrain, in nuclei of the ventral midbrain and hindbrain at 13.5 dpc. In the spinal cord, expressed as a gradient in the dorsal part of the neuroepithelium at 13.5 dpc. In the neocortical neuroepithelium, expressed in the archicortex (in the dentate gyrus, CA3 and CA4), the diencephalon, the midbrain and hindbrain at 14.5 and 16.5 dpc.