Required for efficient abscission at the end of cytokinesis, together with components of the ESCRT complexes. Seems not to be involved in endosomal transport (By similarity). Homodimer. Interacts (via MIT domain) with CHMP1A, CHMP1B, CHMP2A and IST1 (By similarity). During cytokinesis, recruited to the midbody via interaction with CHMP1A. Interacts with membranes enriched in phosphoinositides (By similarity). The C-terminal domain interacts with lipid membranes containing acidic phosphoinositides and is required for location at the midbody. The MIT domain interacts with the MIT-interacting motifs of several components of the ESCRT-III complex.