May participate in the regulation of cell proliferation through the E2F/RB pathway (By similarity). May be involved in molecular regulation of hematopoietic stem cells and progenitor cell lineage commitment and differentiation. Expressed preferentially in hematopoietic progenitors and mature blood cells. Expressed at low levels in the heart, lung, spleen, and thymus and at a higher level in muscle. Developmentally regulated. Preferential expression in both fetal and adult hematopoietic progenitors and mature blood cells during embryonic and adult hematopoiesis.