Tyrosine-rich conopeptide that targets several channels/receptors that are expressed in Xenopus oocytes. These targets are the voltage-gated potassium channels Kv1.6/KCNA6 (IC(50) is 170 nM) and Kv1.2/KCNA2 (IC(50) is 2.0 uM), Nav1.2/SCN2A (30% of inhibition), and N-methyl-D-aspartate (NMDA) receptor (GRIN1/GRIN2A/GRIN3B and GRIN1/GRIN2B/GRIN3B) (15% of inhibition). In vivo, causes the marine worm N.virens to move very slowly in contrast to control worms, and causes seizures (at 5 nmol) and death (20 nmol) to mice when intracranially injected. Expressed by the venom duct. The mature peptide does not contain cysteine residues. Does not target Kv1.3/KCNA3 (IC(50) is >50 uM), Kv1.4/KCNA4 (IC(50) is >50 uM), Kv1.5/KCNA5 (IC(50) is >5 uM). Belongs to the conotoxin M superfamily. Conopeptide Y family.