Rnase which modulates cell survival under stress conditions. Released from the vacuole to the cytoplasm during stress to promote tRNA and rRNA cleavage and to activate separately a downstream pathway that promotes cell death. Involved in cell size, vacuolar morphology and growth at high temperatures and high salt concentration. a ribonucleotidyl-ribonucleotide-RNA + H2O = a 3'-end 3'-phospho-ribonucleotide-RNA + a 5'-end dephospho-ribonucleoside-RNA + H(+) Is released from the vacuole to the cytoplasm during stress conditions like oxidative stress or stationary phase stress. Up-regulated by heat shock and osmotic stress. N-glycosylated. Present with 504 molecules/cell in log phase SD medium. Belongs to the RNase T2 family.