Gamma-conotoxins may act on voltage-gated non-specific cation pacemaker channels (HCN). Expressed by the venom duct. The presence of a 'disulfide through disulfide knot' structurally defines this protein as a knottin. The cysteine framework is VI/VII (C-C-CC-C-C). Decarboxylated. Belongs to the conotoxin O1 superfamily.