Disease resistance (R) protein that mediates resistance against Hyaloperonospora parasitica in a salicylic acid-dependent manner. Also mediates resistance against Erysiphe cichoracearum is both salicylic acid-dependent and partially NPR1-dependent. Resistance proteins guard the plant against pathogens that contain an appropriate avirulence protein via an indirect interaction with this avirulence protein. That triggers a defense system including the hypersensitive response, which restricts the pathogen growth. Accumulates in leaves 1.5 hours postinfiltration of Pseudomonas syringae. The LRR repeats probably act as specificity determinant of pathogen recognition. Belongs to the disease resistance NB-LRR family. Functional and comparative genomics of disease resistance gene homologs