Secreted effector that effector that induces cell death when expressed in host plants (PubMed:19741609, PubMed:20847293). Induces the expression of defense response genes in tomato (PubMed:12840044). Expressed during colonization of the host plant tomato by P.infestans. The CRN proteins have modular architectures that include a signal peptide, a conserved N-terminus, and highly diverse C-terminal domains. The conserved CRN N-terminus harbors a distinct LXLFLAK motif, which is followed by the conserved DWL domain. A highly conserved HVLVXXP motif marks the end of the CRN N-terminal domains and forms a junction where diverse C-terminal domains are fused. The conserved CRN N-terminus mediates the translocation into the plant host cells. Belongs to the Crinkler effector family.