Binds to chromosome ends in a sequence-dependent manner and is required for telomere capping. Interacts (via C-terminus) with Su(var)205 dimer (via hinge and chromoshadow domain) and with moi to form the terminin telomere-capping complex. Interacts with HP6, which is also part of the terminin complex. Enriched at interphase, polytene and mitotic chromosome telomeres. Localized predominantly at telomeres and diffusely throughout regions of pericentric heterochromatin. Expressed both maternally and zygotically. Death at the larval/pupal boundary due to extensive telomere-telomere fusions in larval brain cells. Multiple telomeric associations (TAs) in the same metaphase spread often result in multicentric linear chromosomes that resemble little 'trains' of chromosomes, hence the name 'caravaggio', an Italian train.