Catalyzes the N-acetylation of the amino acid thialysine (S-(2-aminoethyl)-L-cysteine), a L-lysine analog with the 4-methylene group substituted with a sulfur (PubMed:15283700). Substrate specificity: thialysine > O-(2-aminoethyl)-L-serine > S-(2-aminoethyl)-D,L-homocysteine (PubMed:15283700). Does not act on polyamines, such as spermidine and spermine, nor on diamines putrescine and cadaverine (PubMed:15283700). acetyl-CoA + S-(2-aminoethyl)-L-cysteine = CoA + H(+) + S-(2-acetamidoethyl)-L-cysteine acetyl-CoA + O-(2-aminoethyl)-L-serine = CoA + H(+) + O-(2-acetamidoethyl)-L-serine acetyl-CoA + S-(2-aminoethyl)-homocysteine = CoA + H(+) + S-(2-acetamidoethyl)-homocysteine kcat is 38.5 sec(-1) with thialysine (S-(2-aminoethyl)-L-cysteine) as substrate (PubMed:15283700). kcat is 48.9 sec(-1) with O-(2-aminoethyl)-L-serine as substrate (PubMed:15283700). kcat is 27.7 sec(-1) with S-(2-aminoethyl)-D,L-homocysteine as substrate (PubMed:15283700). kcat is 1.4 sec(-1) with L-lysine as substrate (PubMed:15283700). kcat is 5.8 sec(-1) with ethylenediamine as substrate (PubMed:15283700). kcat is 1.2 sec(-1) with diaminopropane as substrate (PubMed:15283700). kcat is 0.14 sec(-1) with spermidine as substrate (PubMed:15283700). Homodimer. Belongs to the acetyltransferase family.