Secreted effector that possesses RNA silencing suppression activity by inhibiting the biogenesis of small RNAs in the host plant to promote enhanced susceptibility of host to the pathogen during infection (PubMed:23377181, PubMed:25387135, PubMed:30595554). Interferes with secondary siRNA production by associating with host dsRNA-binding protein DRB4 (PubMed:30595554). Inhibits the host salicylic acid pathway during infection (PubMed:25387135). Interacts with host dsRNA-binding protein DRB4. Expressed at specific infection stages in a transient manner (PubMed:25387135). Is not expressed until 24 hours post-infection (hpi) but quickly reaches the maximum expression level at approximately 36 hpi (PubMed:25387135). The abundance of transcripts exhibits a more than twofold decrease at 48 hpi (PubMed:25387135). The RxLR-dEER motif acts to carry the protein into the host cell cytoplasm through binding to cell surface phosphatidylinositol-3-phosphate. The C-terminal region (residues 79 to 670) consists of seven imperfect tandem repeats, including one W-Y motif (WY1) and six L-W-Y motifs (LWY2 to LWY7) (Probable). WY1 forms a 3 alpha-helix fold with one hydrophobic core and each L-W-Y motif forms a highly conserved fold consisting of 5 alpha-helices (Probable). The units contribute differently to the virulence since WY1, LWY2 and LWY6 are important for the ability to suppress the biogenesis of small RNA in host and virulence activity of the pathogen, whereas LWY3, LWY4, LWY5 and LWY7 are dispensable for PSR2 function (PubMed:30926664). WY1 and LWY2 are sufficient for association with DRB4, suppress gene silencing and promote infection (PubMed:30595554). These units may function as basic building blocks of Phytophthora effectors to enable virulence activity and accelerate the evolution of novel functions (Probable). Exhibits significantly decreased virulence when infecting soybean seedlings. Belongs to the RxLR effector family.