Component of the ESCRT-0 complex which is the sorting receptor for ubiquitinated cargo proteins at the multivesicular body (MVB) and recruits ESCRT-I to the MVB outer membrane. Component of the ESCRT-0 complex composed of HSE1 and VPS27 (PubMed:12055639). Interacts with the ESCRT-I subunit VPS23, the UBP7 deubiquitinase and the E3 ligase RSP5 (PubMed:17079730, PubMed:15086794). May form a complex composed of VPS27, HSE1 and DOA1 (PubMed:18508771). Interacts (via SH3 domain) with DOA1 (PubMed:18508771). Present with 358 molecules/cell in log phase SD medium. Belongs to the STAM family.