Catalyzes the decarboxylative condensation of pimeloyl-[acyl-carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide (By similarity). Can also use pimeloyl-CoA instead of pimeloyl-ACP as substrate. To a lesser extent, can also utilize D-alanine instead of L-alanine as substrate. 6-carboxyhexanoyl-[ACP] + H(+) + L-alanine = (8S)-8-amino-7-oxononanoate + CO2 + holo-[ACP] Inhibited by D-alanine and D-7-keto-8-amino-pelargonic acid. kcat is 0.007 sec(-1) and 0.0036 sec(-1) with L-alanine and D-alanine as substrate, respectively, and pimeloyl-CoA as co-substrate. Cofactor biosynthesis; biotin biosynthesis. Homodimer. Cells lacking this gene are shown to be highly attenuated in a mouse tuberculosis model (PubMed:14569030). Essential for growth even in liquid culture; growth does not occur on biotin-containing medium after biotin deprivation (PubMed:20565114). Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. BioF subfamily.