Specifically phosphorylates the activated forms of G protein-coupled receptors (By similarity). Required in adult sensory neurons for chemotaxis (PubMed:15157420). Plays a role in the ASH sensory neurons in the chemotaxis response to NaCl where it is likely to modulate the strength of the NaCl avoidance response which occurs at high NaCl concentrations (PubMed:16407969). Required in the HSN motor neurons for normal egg laying by promoting phosphorylation of amine oxidase amx-2 which inhibits amx-2 activity, preventing metabolism of serotonin (PubMed:28213524). Acts in head acetylcholine neurons to positively regulate locomotion (PubMed:28968387). Inactivates dopamine receptor dop-3 which leads to inactivation of guanine nucleotide-binding protein G(o) subunit goa-1 and activation of the unc-77/nca-1 and nca-2 ion channel proteins (PubMed:28968387). [G-protein-coupled receptor] + ATP = [G-protein-coupled receptor]-phosphate + ADP + H(+) Interacts with amx-2; the interaction promotes phosphorylation of amx-2. Expressed in many neurons in the adult including the ASH neurons and other sensory neurons, many interneurons, and motor neurons of the ventral nerve cord (PubMed:15157420). Expressed broadly in head neurons and is detected in several head acetylcholine neurons including the AVA, AVB, AVD and AVE premotor interneurons, the SMD and RMD head motor neurons, and the AIN, AIY, SIA, SIB and SAA interneurons (PubMed:28968387). Expressed in HSN motor neurons and VC4/VC5 motor neurons (PubMed:28213524). Also expressed in vulval muscle cells (PubMed:15157420, PubMed:28213524). Expression is observed in embryos as early as the 20-30 cell stage and persists throughout development and into adulthood. The kinase domain is required for chemotaxis activity. Defective egg-laying with mutants retaining 35 eggs compared to 13-14 eggs in wild-type worms (PubMed:28213524, PubMed:28968387). Reduced serotonin levels, increased levels of the serotonin metabolite 5-hydroxyindoleacetic acid, increased levels of amine oxidase amx-2 in early adult stages and reduced levels of phosphorylated amx-2 (PubMed:28213524). Defective locomotion and reduced body length (PubMed:28968387). Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily.