Phosphatase that has a high activity toward phosphoethanolamine (PEA) and phosphocholine (PCho). Involved in the generation of inorganic phosphate for bone mineralization. H2O + phosphoethanolamine = ethanolamine + phosphate H2O + phosphocholine = choline + phosphate Localizes to special class of extracellular vesicles, named matrix vesicles (MVs), which are released by osteogenic cells. Belongs to the HAD-like hydrolase superfamily. PHOSPHO family.