Non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides. Homodimer. Belongs to the ABC transporter superfamily. Macrolide exporter (TC 3.A.1.122) family. Produces two separate ORFs. Produces two separate ORFs.