Receptor which shows binding specificity for the cytokine ifng1r (interferon gamma-related). Highly expressed in spleen. Also detected in brain, kidney, gill, intestine and heart. Expressed at very low levels in muscle. In immune cell populations, shows highest expression in monocytes, and slightly lower expression in peripheral blood leukocytes, splenocytes, neutrophils and mature macrophages. Up-regulated in response to ifng1 (interferon gamma 1), tgfb1b (TGF-beta), and tnfb (TNF-alpha 2). Belongs to the type II cytokine receptor family.