Microtubule-binding protein required to ensure proper cell division and nuclear envelope reassembly by sequestering the endoplasmic reticulum away from chromosomes during mitosis. Probably acts by clearing the endoplasmic reticulum membrane from metaphase chromosomes (By similarity). May play a role in the maintenance of both the nervous system and the musculature. Interacts with microtubules. During gastrulation, expressed on the dorsal side of the embryo and then in the neural plate and neural tube. At tailbud stages, expressed in the somites, neural tube and otic vesicle. Expressed maternally and zygotically. Maternal expression declines during cleavage stages and gastrulation. Expression then increases during neurula and tailbud stages. Inactivation in embryos by antisense morpholino causes paralysis and shortening of the body axis. Belongs to the DP1 family.