Both native and recombinant protein bound to labeled vitronectin, fibrinogen, recombinant osteopontin and fibronectin. It was also shown to be able to bind to a 15-amino acid synthetic peptide of vitronectin. Map could affect the severity of arthritis and osteomyelitis in mice through a T-cell-mediated mechanism and could play a role in abscess formation through a T-cell-independent mechanisms. It could potentiate the survival of the bacterium by modulating host immunity (By similarity). Each MAP domain contains a 31-residue subdomain that shares striking sequence homology with a segment present in the peptide binding groove of the beta chain of the MHC class II proteins from different mammalian species.