As a homodimer binds DNA via the E-box sequence 5'-CACGTG-3' (PubMed:19632181). Represses lag-2 transcription during embryogenesis via Notch signaling, in an unc-37-dependent manner (PubMed:15935776). Also represses tbx-37 independent of Notch signaling (PubMed:15935776). In the intestine, plays a role in probiotic-mediated protection against infections by pathogens such as S.enterica (PubMed:35263319). This is most likely by positively regulating the expression of genes such as bar-1 upon exposure to probiotic bacteria such as the E.faecium (PubMed:35263319). Homodimer; binds to DNA as a homodimer. Expressed in intestinal cells (at protein level). Expressed in AB cell descendants in embryos. RNAi-mediated knockdown in the intestine decreases the E.faecium-mediated protection against S. enterica infection (PubMed:35263319). RNAi-mediated knockdown reduces the expression of genes including bar-1 following E.faecium infection (PubMed:35263319). RNAi-mediated knockdown in the germline or the nervous system does not affect E.faecium-mediated protection against S.enterica infection (PubMed:35263319).