Nucleoporin essential for nuclear pore assembly and fusion, nuclear pore spacing, as well as structural integrity. Forms dimers and possibly higher-order oligomers. Ubiquitous expression, with highest levels in lung, liver, pancreas, testis, and ovary, intermediate levels in brain, kidney, and spleen, and lowest levels in heart and skeletal muscle. N-glycosylated, but not all potential glycosylation sites may be used. Contains high-mannose type oligosaccharides (By similarity). Phosphorylated at Ser-1881 in mitosis specifically; not phosphorylated in interphase. Recognized by antinuclear autoantibodies in primary biliary cirrhosis. Knockdown of NUP210 causes nuclear membranes to accumulate aberrant structures termed twinned and fusion-arrested membranes and nuclear pore complex to cluster. Induces cell death and chromatin disruptions. Belongs to the NUP210 family.