Transcription factor involved in vascular assembly and morphogenesis through direct transcriptional regulation of EGFL7. Expressed in the brain stem and the thalamencephalon. First expressed at 8.0 dpc in the developing heart and throughout development. By 8.5 dpc, it is expressed in the lateral neural folds of the hindbrain and extends anteriorly and posteriorly to eventually cover the dorsal neural tube from the isthmus to its caudal end. From 9.5 dpc, it is expressed in the dorsomedial telencephalon. In the hindbrain, it is confined to trigeminal motor neurons and to migrating facial branchiomotor neurons. In the peripheral nervous system, it is expressed in cranial and in dorsal root ganglia. Also expressed in the developing eye and in the nasal placode. Up-regulated during myoblast differentiation.