May play a role in motor coordination and exploratory behavior. Expressed in various neuronal structures during embryonic development, including spinal ganglia, trigeminal nerve and ganglion, olfactory and nasopharyngeal epithelium, nuclei of the metencephalon, thalamus and medulla oblongata. Also expressed in lung, esophagus, epiglottis, ependyma, vertebral column, spinal cord and brown adipose tissue. Expression persists in the adult brain with dynamically changing patterns in cortex and cerebellum. Mice are viable and show no apparent anatomical defects. However, they display significantly altered motor coordination and aberrant exploratory behavior. Belongs to the class I-like SAM-binding methyltransferase superfamily. Trm1 family. Extended N-terminus.