Activates large conductance calcium-activated potassium channels (maxiK, KCNMA1/KCNMB), when tested at micromolar concentrations, suggesting a potential mechanism for regulating host blood supply during feeding (PubMed:19394347). Shows no antiprotease activity, and does not prevent ADP-, PAF- or collagen-induced platelet aggregation (PubMed:19394347). Has no effect on blood coagulation and does not inhibit the alternative or classical complement cascades (PubMed:19394347). Monomer. Expressed by the salivary glands. Only detected in the salivary glands of adult female ticks between 2 to 4 days after attachment to the host animal. Is not obtained from nymphs, larvae or adult male ticks. Is only detected in a quarter of pairs of glands, suggesting non-continuous production of the protein or slow repletion of stocks following salivation.