Sequence-specific transcriptional activator. Recognizes the DNA sequence 5'-C[CA]GGAAGT-3'. Can form homodimers or heterodimers with ETV6/TEL1. Expressed in both hematopoietic and nonhematopoietic tissues. Specifically up-regulated in leukemic clones with F-MuLV insertions up-stream of the FLI-1 locus. Involved in erythroleukemia induction by Friend murine leukemia virus (F-MULV). Belongs to the ETS family.