May function as a regulatory ATPase and be related to secretion/protein trafficking process. Involved in mitochondrial-mediated antiviral innate immunity, activates RIG-I-mediated signal transduction and production of IFNB1 and pro-inflammatory cytokine IL6 (PubMed:31522117). ATP + H2O = ADP + H(+) + phosphate Interacts with PHB and PHB2 (PubMed:31522117). Interacts with MAVS; the interaction is enhanced by Sendai virus infection (PubMed:31522117). Widely expressed (at protein level) (PubMed:25597511). Expressed in fetal, as well as in adult tissues, with highest levels in adult brain, including thalamus, hippocampus, occipital cortex and parietal cortex. Low expression in granulocytes (PubMed:25597510). The disease is caused by variants affecting the gene represented in this entry. Belongs to the ClpA/ClpB family.