May play a role in neural and muscle differentiation (By similarity). May be involved in transcriptional regulation. Expressed in brain, skeletal muscle and liver. Very low expression in stomach. A chromosomal aberration involving ZFHX4 is found in one patient with ptosis. Translocation t(1;8)(p34.3;q21.12). Belongs to the krueppel C2H2-type zinc-finger protein family.