May play a role in cell-cell and cell-matrix interactions. This is a non-catalytic metalloprotease-like protein. Can bind to LGI1 and LGI4 (By similarity). Ligand for integrin alpha-V/beta-3. Highly expressed in the brain and weakly expressed in the heart. In the brain, expressed prominently in the amygdala, caudate nucleus, hypothalamus, thalamus, cerebral cortex and occipital pole. Highly expressed in the fetal brain. A conserved motif AVN[ED]CD within the disintegrin-like domain could be involved in the binding to the integrin receptor.