Zinc-activated ligand-gated ion channel. Detected in pancreas, brain, liver, placenta, trachea, kidney, spinal cord, stomach and fetal brain. In the adult brain region expression is detected in the hippocampus, striatum, amygdala and thalamus. Glycosylated. The mouse and rat orthologous proteins do not exist. May be produced at very low levels due to a premature stop codon in the mRNA, leading to nonsense-mediated mRNA decay. Belongs to the ligand-gated ion channel (TC 1.A.9) family. It is uncertain whether Met-1 or Met-2 is the initiator. Truncated N-terminus. Truncated N-terminus. Truncated N-terminus.