Snake venom zinc metalloproteinase-disintegrin that causes hemorrhage by provoking the degradation of the sub-endothelial matrix proteins (fibronectin, laminin, type IV collagen, nidogen, and gelatins) and disturbances in platelet function. The recombinant cysteine-rich domain interacts with the alpha-2/beta-1 integrin (ITGA2/ITGB1) (collagen receptor), and inhibits the platelet aggregation induced by collagen. Cleavage of 3-Asn-|-Gln-4, 5-His-|-Leu-6, 10-His-|-Leu-11, 14-Ala-|-Leu-15 and 16-Tyr-|-Leu-17 in insulin B chain. Removes C-terminal Leu from small peptides. Binds 1 zinc ion per subunit. Monomer. Expressed by the venom gland. The recombinant cysteine-rich domain does not inhibit ADP-induced platelet aggregation (PubMed:10620350) as well as convulxin-induced platelet aggregation, demonstrating no activity on the other collagen receptor GPVI (GP6) (PubMed:12914938). Belongs to the venom metalloproteinase (M12B) family. P-III subfamily. P-IIIa sub-subfamily.