Squalene cyclase that catalyzes the oxygen-independent cyclization of squalene into hopanoids, a class of cyclic triterpenoids including hop-22(29)-ene, hop-17(21)-ene, hop-21(22)-ene, and hopan-22-ol. squalene = hop-22(29)-ene H2O + squalene = hopan-22-ol The fast anaerobic growth of Schizosaccharomyces japonicus in sterol-free media is an interesting trait for developing robust fungal cell factories for application in anaerobic industrial processes. Belongs to the terpene cyclase/mutase family.