Snake venom phospholipase A2 (PLA2) that exhibits an indirect hemolytic activity, a low myotoxicity, and induces edema. In addition, this enzyme has been shown to induce the release of some pro- and anti-inflammatory cytokines from human PBMC (IL12B, TNF-alpha, IL1B and IL6 but not variation has been observed for IL-8 and IL-10). PLA2 catalyzes the calcium-dependent hydrolysis of the 2-acyl groups in 3-sn-phosphoglycerides. a 1,2-diacyl-sn-glycero-3-phosphocholine + H2O = a 1-acyl-sn-glycero-3-phosphocholine + a fatty acid + H(+) Binds 1 Ca(2+) ion. Monomer. Expressed by the venom gland. Belongs to the phospholipase A2 family. Group II subfamily. D49 sub-subfamily.