GPI-anchored cell wall protein required for mating efficiency, biofilm formation, and virulence. Involved in normal disseminated infection, but not in intestinal colonization. Expression is negatively regulated by the TUP1 transcriptional repressor. Also regulated by EFG1, RFG1 and RIM101. Induced during hyphal growth, during mating process, under alkaline conditions, and by farnesol. Repressed by fluconazole. The GPI-anchor is attached to the protein in the endoplasmic reticulum and serves to target the protein to the cell surface. There, the glucosamine-inositol phospholipid moiety is cleaved off and the GPI-modified mannoprotein is covalently attached via its lipidless GPI glycan remnant to the 1,6-beta-glucan of the outer cell wall layer (By similarity). Leads to hypersensitivity to calcofluor white (CFW). Belongs to the HWP1 family.