Cell surface adhesion protein which mediates both yeast-to-host tissue adherence and yeast aggregation. Plays an important role in the pathogenesis of C.albicans infections. Identified as covalently-linked GPI-modified cell wall protein (GPI-CWP) in the outer cell wall layer. Covers the surface of yeast-form cells. Each ALS protein has a similar three-domain structure, including a N-ter domain of 433-436 amino acids that is 55-90 percent identical across the family and which mediates adherence to various materials; a central domain of variable numbers of tandemly repeated copies of a 36 amino acid motif; and a C-ter; domain that is relatively variable in length and sequence across the family. N-glycosylated and O-glycosylated. Belongs to the ALS family.