Amphipathic alpha-helical antimicrobial peptide with weak to moderate activity against Gram-positive bacteria, and no activity against Gram-negative bacteria (PubMed:10951191, PubMed:17259271). Probably acts by disturbing membrane functions with its amphipathic structure (PubMed:10951191). Strongly inhibits the formation of NO by neuronal nitric oxide synthase (nNOS) at micromolar concentrations (PubMed:11784303). Acts by a non-competitive mechanism, probably by binding to calcium/calmodulin and as a consequence blocking calmodulin attachment to nNOS (By similarity). Expressed by the skin dorsal glands. Amidation is essential for antibacterial activity against Gram-positive bacteria. Belongs to the frog skin active peptide (FSAP) family. Aurein subfamily.