Interacts with CRISP3. Expressed in the liver hepatocytes of male and female GH transgenic mice and in the liver of female, but not of male, non-transgenic mice. Expressed at 3-days but not at 11-days of age in both female and male GH transgenic mice. Expression in the normal female mice begins as early as 2 months and is detected at much higher levels at 5, 12 and 24 months while at 30 months, expression is lower. Induced in hepatocytes during the proliferative phase of liver regeneration. Induction requires a continuous pattern of GH (growth hormaone) secretion and an intact GH-GH receptor-signaling complex.