May be involved in transcriptional regulation as a transcriptional corepressor. The DEPDC1A-ZNF224 complex may play a critical role in bladder carcinogenesis by repressing the transcription of the A20 gene, leading to transport of NF-KB protein into the nucleus, resulting in suppression of apoptosis of bladder cancer cells (By similarity). Can form dimers. Interacts with ZNF224 (By similarity). Colocalizes with ZNF224 at the nucleus. Truncated N-terminus.