Drastically down-regulated in response to PDGF-BB or cell injury, that promote smooth muscle cell proliferation and dedifferentiation. Seems to play a role in the development of the embryonic vascular system. Interacts with KAT14. The LIM domain 1 is necessary and sufficient for this interaction (By similarity). Interacts with GLRX3 (By similarity). Highly expressed in the aorta; weakly found in the kidney, thymus, and intestine. Barely detectable in brain, testis, esophagus, lung, liver, aortic adventitia, vena cava, or uterus; not present in heart and skeletal muscle.