ATP-binding RNA helicase involved in the biogenesis of 60S ribosomal subunits and is required for the normal formation of 25S and 5.8S rRNAs. ATP + H2O = ADP + H(+) + phosphate Interacts with RRP1 and associates with pre-ribosomal particles. The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis. Belongs to the DEAD box helicase family. DDX54/DBP10 subfamily.