Shows antibacterial activity against B.cereus, L.lactis, L.innocua, M.luteus, S.aureus, P.multoci, S.hominis, S.epidermidis and S.uberis (Ref.1, PubMed:33431675). Strong activity against M.luteus (MIC=2 uM) compared to S.hominis, S.epidermidis and S.aureus (PubMed:33431675). Acts by inducing permeabilization of bacterial membranes (PubMed:33431675). Forms amyloid fibrils which, in the presence of bacteria, aggregate on the bacterial membrane leading to severe membrane damage and cell death (Ref.3, PubMed:33431675). Thermostable (PubMed:33431675). Retains antibacterial activity against M.luteus after heat treatment at 60 degrees Celsius for 10 minutes (PubMed:33431675). Monomer and homodimer (PubMed:26676975, PubMed:33431675). Assembles into amyloid fibrils (PubMed:26676975, Ref.3, PubMed:31385514, PubMed:33431675). Under lipid-free conditions, mostly forms fibrils with a cross-beta architecture, consisting of stacks of monomeric amphipathic beta-helices arranged in an antiparallel manner (PubMed:26676975, PubMed:31385514, PubMed:33431675). In the presence of bacteria or membrane lipids, fibrils switch to a cross-alpha conformation which may correlate with its antibacterial activity (PubMed:26676975, Ref.3, PubMed:31385514, PubMed:33431675). Secreted monomers and fibrils appear to be able to interact with target cell membranes. Expressed by the skin dorsal glands. The amyloid fibrils are cytotoxic to PC12 neuronal cells, whereas the native peptide displays relatively weak cytotoxic activity (PubMed:26676975). Interacts with mammal mimetic membranes (DMPC:chol) leading to transmembrane pores (Ref.3).