Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, neurotransmitter release, gene expression, cell motility, cell division and cell death (By similarity). Probably encodes a dihydropyridine-insensitive current. Vital for survival to adulthood. At least 2 regions (Exon IS4 and Exon I/II) undergo alternative splicing. The total number of isoforms is currently not known. Expressed widely in the embryonic nervous system. Expression peaks in the first larval instar, midpupal, and late pupal stages. In late-stage embryos, it is expressed preferentially in the nervous system. Each of the four internal repeats contains five hydrophobic transmembrane segments (S1, S2, S3, S5, S6) and one positively charged transmembrane segment (S4). S4 segments probably represent the voltage-sensor and are characterized by a series of positively charged amino acids at every third position. Partially edited. 11 sites are edited by Adar. Has exons IS4B and I/IIA. Has exons IS4B and I/IIA. Has exons IS4A and I/IIA. Has exons IS4B and I/IIB. Has exons IS4A and I/IIB. Has exons IS4A and I/IIB. Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family.