PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. This isozyme is required for growth on lactate at high temperature. [protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0) Inhibited by the immunosuppressant drug cyclosporin A and by SDZ NIM811, a PPIase inhibitor. Present with 1960 molecules/cell in log phase SD medium. Belongs to the cyclophilin-type PPIase family.