Catalyzes the reduction of pyridoxal (PL) with NADPH and oxidation of pyridoxine (PN) with NADP(+). Involved in the PLP salvage pathway. NADP(+) + pyridoxine = H(+) + NADPH + pyridoxal Optimum pH is 6-7.5 for the reverse reaction. Cofactor degradation; B6 vitamer degradation; pyridoxal from pyridoxine (dehydrogenase route): step 1/1. Monomer. Expressed in cotyledons, embryos, flowers, shoots, roots and seeds. Mutants with reduced expression of PLR1 have lower levels of total B6 vitamers but there is no reduction in PN or PNP levels. Belongs to the aldo/keto reductase family.