Final heterodimeric neurohormone released at the end of the molting cycle, involved in the sclerotization (tanning) of the insect cuticle, melanization and wing spreading. Heterodimer of burs and pburs. Central nervous system. Coexpressed with CCAP in most CCAP-specific neurons. Coexpressed with pburs in the large bilateral lateral neurosecretory neurons of the first three unfused abdominal ganglia and in all anterior bilateral cell pairs in the thoracic ganglia. The order of the 5th peptide within the sequence is unknown.