One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. May play a role in myelination in central and peripheral nervous systems. A connexon is composed of a hexamer of connexins. Interacts with TJP1 (By similarity). Expressed in central nervous system, in sciatic nerve and sural nerve. Also detected in skeletal muscles. The disease is caused by variants affecting the gene represented in this entry. The disease is caused by variants affecting the gene represented in this entry. The disease is caused by variants affecting the gene represented in this entry. Belongs to the connexin family. Gamma-type subfamily. It is uncertain whether Met-1 or Met-4 is the initiator. Truncated N-terminus. Truncated N-terminus.