May play a role in cell survival and cell growth. May suppress the transcriptional activity of p53/TP53. Interacts with the DNA-binding domain of p53/TP53. Expressed in all tissues tested with higher expression in placenta, liver, kidney, heart and brain. Depletion of isoform 2 results in cell apoptosis while its overexpression in cells leads to accelerated growth rate and tumorogenicity.