May play a synaptic role at the postsynaptic lipid rafts possibly through interaction with CAMK2A. Interacts with CAMK2A. In neurons, localizes to postsynaptic lipid rafts (PubMed:15659234). In myocardial and skeletal muscle cells, localizes to the cytoplasm adjacent to the inner cell membrane, polarized to one end of the myocyte (By similarity). Predominantly expressed in the brain (at protein level) (PubMed:11707601, PubMed:15659234). Within the brain, found in most of forebrain structures, including the cerebral cortex, hippocampal formation, olfactory bulb, anterior olfactory nuclei, piriform cortex, tenia tecta and amygdaloid nuclei. Not detected in glial cells (PubMed:15659234). In the developing forebrain, barely detected at postnatal day 1. Expression increases from the first week after birth. High levels are reached during 2 and 3 weeks after birth and slightly decrease at 6 weeks after birth. This expression pattern parallels synaptogenesis. Palmitoylation and myristoylation target the protein to the lipid rafts.