Receptor for SEMA7A, for smallpox semaphorin A39R, vaccinia virus semaphorin A39R and for herpesvirus Sema protein. Binding of semaphorins triggers cellular responses leading to the rearrangement of the cytoskeleton and to secretion of IL6 and IL8 (By similarity). Monomer. Homodimer. Interacts with SEMA7A. Detected in heart, brain, lung, spleen and placenta. N-glycosylated. Belongs to the plexin family.