Involved in ciliogenesis. Interacts (via C-terminus) with microtubules. Interacts with LCA5, CEP290 and SDCCAG8. Interacts with FAM161B. Interacts with POC1B. Interacts with CEP78 (PubMed:27588451). Localized to the region between the outer and inner photoreceptor segments, corresponding to the photoreceptor connecting cilium. Isoform 1 and isoform 3 are widely expressed with highest levels in retina and testis, with isoform 1 being the most abundant in all tissues tested. The disease is caused by variants affecting the gene represented in this entry. Belongs to the FAM161 family. Truncated N-terminus.