Transcription factor; part of the gene cluster that mediates the biosynthesis of the toxin tenuazonic acid (TeA), an inhibitor of protein biosynthesis on ribosomes by suppressing the release of new protein (PubMed:28820236, PubMed:32765467). Directly regulates the expression of the hybrid PKS-NRPS synthetase TAS1 and the susequent production of TeA (PubMed:32765467). Expression is induced by the presence of dimethylsulphoxide (DMSO) or by the deletion of OSM1, a HOG1-related mitogen-activated protein kinase (PubMed:28820236). Expression is positively regulated by the secondary metabolism regulator LAE1 (PubMed:28820236). Infection by the totivirus induces the transcription of TAS2 (PubMed:32765467). Impairs the ability to produce TeA under the DMSO-added, TeA-inducing culture conditions.