May be required for efficient PLK4 centrosomal localization and PLK4-induced overduplication of centrioles (PubMed:27246242). May play a role in cilium biogenesis (PubMed:27588451). Interacts with PLK4 (PubMed:27246242). Interacts with FAM161A (PubMed:27588451). Mainly localizes at the centriolar wall, but also found in the pericentriolar material (PubMed:27246242). Expressed in photoreceptor inner segment (PubMed:27588452). Widely expressed (PubMed:27588451, PubMed:27588452). Expressed in different retinal cell types with higher expression in cone compared to rod cells (at protein level) (PubMed:27588452). Expression is cell cycle-dependent, with low levels in mitosis. The expression starts to increase during late G1 until the S/G2 transition (at protein level). The disease is caused by variants affecting the gene represented in this entry. Belongs to the CEP78 family. Truncated N-terminus. Probable intron retention.