May be involved in autophagy-related processes. Unlike other Rab family members, does not interact with GDP dissociation inhibitors (GDIs), including ARHGDIA and ARHGDIB. Interacts with ZFYVE20. Only about 20-25% is recovered in the particulate fraction. By extensive retinoic acid treatment, in Ntera-2 teratoma cell line induced to differentiate into post-mitotic neurons (NTN2) (at protein level). Isoprenylation is inefficient compared to other Rab family members. The unusual Ser-67, instead of a conserved Gln in other family members, is the cause of low GTPase activity. As a result, the predominant nucleotide associated with the protein is GTP (By similarity). Belongs to the small GTPase superfamily. Rab family.