The heterodimer bitisgabonin-2 preferentially inhibits the adhesion of the alpha-4/beta-1 (ITGA4/ITGB1) and alpha-9/beta-1 (ITGA9/ITGB1) integrins to VCAM-1 and acts also as a strong antagonist of alpha-5/beta-1 (ITGA5/ITGB1). Heterodimer with bitisgabonin (bitisgabonin-2 is the name of the heterodimer); disulfide-linked. Expressed by the venom gland. Belongs to the disintegrin family. Dimeric disintegrin subfamily.