May function as a transcription repressor. Binds to 5'-CCACA-3' core sequence. Suppresses osteogenic effects of RUNX2. May be involved in osteoblastic differentiation. Plays a role in postnatal myogenesis, may be involved in the regulation of satellite cells self-renewal (By similarity). Interacts with RUNX2. Binds consensus element OSE2. Expressed in brain. Very low expression in adult bone tissues. Overexpression suppresses alkaline phosphatase induction by BMP7. Expressed during osteoblast differentiation and bone development. Detected in embryonic bone formation in calvariae and tibiae. Very low expression in neonate bone tissues. Expressed in kidney and brain. KRAB domain is not required for nuclear targeting or for DNA binding. Zinc finger region is involved in nuclear targeting and DNA-binding. Belongs to the krueppel C2H2-type zinc-finger protein family.