Required for hepatocyte growth factor (HGF)-dependent activation of Arf6 and HGF-stimulated cell migration. Based on a naturally occurring readthrough transcript which produces an CNK3/IPCEF1 fusion protein. Based on a naturally occurring readthrough transcript which produces an CNK3/IPCEF1 fusion protein. Based on a naturally occurring readthrough transcript which produces an CNK3/IPCEF1 fusion protein. Major isoform found in CaCo2-cells. Belongs to the CNKSR family.