glp-1/Notch and lin-12/Notch proteins promote signaling by recruiting lag-3 to target promoters, where it functions as a transcriptional activator, probably as part of a complex with a Notch intracellular domain (NICD) and the transcription regulator lag-1 (PubMed:10830967, PubMed:10884418, PubMed:16530045). Involved in the p53-mediated germ-cell apoptotic response to DNA damage, perhaps acting as a transcriptional activator (PubMed:17317671). May regulate phosphatase lip-1 mRNA transcription downstream of glp-1 (PubMed:16319922). Component of a complex consisting of at least a lin-12/Notch intracellular domain (NICD), lag-1, and lag-3 (PubMed:10830967, PubMed:16530045). Interacts with a NICD of lin-12/Notch or glp-1/Notch; the interactions are direct (PubMed:10830967, PubMed:16530045). Expressed in the progenitor zone and the early pachytene region of the hermaphrodite gonad. RNAi-mediated knockdown causes multiple defects, including large vulval protrusions in hermaphrodites, premature differentiation of germ cells as sperm, and embryonic arrest around the onset of morphogenesis (PubMed:10884418). RNAi-mediated knockdown causes a partial decrease in apoptosis in germ line cells, in the F1 generation, induced by gamma-irradiation (PubMed:17317671). RNAi-mediated knockdown, during treatment by gamma-irradiation, reduces the expression of the p53 target genes, ced-13 and egl-1 (PubMed:17317671).