Catalyzes the dehalogenation of halotyrosines such as 3-bromo-L-tyrosine, 3-chloro-L-tyrosine, 3-iodo-L-tyrosine and 3,5-diiodo-L-tyrosine (PubMed:27643701). Activity towards 3-fluoro-L-tyrosine is weak (PubMed:27643701). Important for male and female fertility (PubMed:29764939). May be involved in maintaining the viability of sperm, both during development in the testes and storage in the female spermatheca (PubMed:29764939). 2 iodide + L-tyrosine + 2 NADP(+) = 3,5-diiodo-L-tyrosine + H(+) + 2 NADPH iodide + L-tyrosine + NADP(+) = 3-iodo-L-tyrosine + NADPH 3-iodo-L-tyrosine + iodide + NADP(+) = 3,5-diiodo-L-tyrosine + H(+) + NADPH chloride + L-tyrosine + NADP(+) = 3-chloro-L-tyrosine + NADPH bromide + L-tyrosine + NADP(+) = 3-bromo-L-tyrosine + NADPH kcat is 12 sec(-1) for the dehalogenation of 3-iodo-L-tyrosine (at pH 7.4 and 25 degrees Celsius) (PubMed:27643701). kcat is 6.9 sec(-1) for the dehalogenation of 3-bromo-L-tyrosine (at pH 7.4 and 25 degrees Celsius) (PubMed:27643701). kcat is 5.0 sec(-1) for the dehalogenation of 3-chloro-L-tyrosine (at pH 7.4 and 25 degrees Celsius) (PubMed:27643701). kcat is 10.8 sec(-1) for the dehalogenation of 3,5-diiodo-L-tyrosine (at pH 7.4 and 25 degrees Celsius) (PubMed:27643701). Homodimer. Expressed in spermatocytes. Adults produce fewer progeny (PubMed:29764939). Larvae display an increase in survival when fed a diet enriched with 3-chloro-L-tyrosine (Cl-Tyr), whereas survival is unaffected when fed a diet containing 3-iodo-L-tyrosine (I-Tyr) or 3-bromo-L-tyrosine (Br-Tyr) (PubMed:29764939). Adult survival is unaffected when fed a diet supplemented with halotyrosines (PubMed:29764939). Named condet in honor of Dr. Jean Francois Condet who discovered that ingestion of iodide could reduce goiter. Belongs to the nitroreductase family.