Acts as an osmosensitive calcium-permeable cation channel (By similarity). Mechanosensitive ion channel that converts mechanical stimuli into a flow of ion (By similarity). (Microbial infection) Involved in the immunomodulatory effects exerted by H.contortus GAL-1 on host peripheral blood mononuclear cells to down-regulate host immune response. (Microbial infection) Interacts with H.contortus GAL-1 (via domain galectin 1). Belongs to the CSC1 (TC 1.A.17) family.