Required to promote assembly of the transition zone in primary cilia. Acts by specifically recognizing and binding the axonemal microtubule. Localizes to the distal end of centrioles throughout the cell cycle. Ubiquitously expressed during early embryonic development. Expressed maternally and zygotically. Cilia defects such as body curvature, hydrocephalus and left-right asymmetry. Ciliogenesis is blocked at the stage of transition zone assembly. Belongs to the CEP162 family.