Reverse transcriptase (RT) responsible for synthesis of msDNA-Mx162 (a branched molecule with RNA linked by a 2',5'-phosphodiester bond to ssDNA). The retron transcript serves as primer (from a conserved internal G residue) and template for the reaction, and codes for the RT (Probable). The retron is involved in antiviral defense (By similarity). a 2'-deoxyribonucleoside 5'-triphosphate + DNA(n) = diphosphate + DNA(n+1) msDNA synthesis is inhibited by rifampicin and chloramphenicol. No production of msDNA. No other visible effect on growth, morphogenesis, fruiting body formation, spore germination or cell motility. M.xanthus contains two independent and unlinked retrons: Mx65 and Mx162. Retrons may be the ancestors of retrovirus. Belongs to the bacterial reverse transcriptase family.