Cytosolic aldehyde dehydrogenase which utilizes NADP(+) as the preferred coenzyme. Performs the conversion of acetaldehyde to acetate. acetaldehyde + H2O + NADP(+) = acetate + 2 H(+) + NADPH H2O + NADP(+) + propanal = 2 H(+) + NADPH + propanoate H2O + NAD(+) + propanal = 2 H(+) + NADH + propanoate The activity is stimulated two- to fourfold by divalent cations but is unaffected by K(+) ions. Alcohol metabolism; ethanol degradation; acetate from ethanol: step 2/2. Present with 135000 molecules/cell in log phase SD medium. Belongs to the aldehyde dehydrogenase family.