Binds to chromosome ends in a sequence-dependent manner and is required for telomere capping. Interacts (via C-terminus) with Su(var)205 dimer (via hinge and chromoshadow domain) and with moi to form the terminin, telomere-capping, complex. Interacts with HP6, which is also part of the terminin complex (By similarity). Multiple telomeric associations (TAs) in the same metaphase spread often result in multicentric linear chromosomes that resemble little 'trains' of chromosomes, hence the name 'caravaggio', an Italian train.