Snake venom metalloproteinase that has high hemorrhagic activity and degrades the alpha-chain of fibrinogen (FGA), leaving the beta- and the gamma-chain intact. It may also inhibit platelet aggregation. Cleaves insulin B chain at '25-Phe-|-Val-26', '26-Val-|-Asn-27', '29-His-|-Leu-30', '30-Leu-|-Cys-31', '33-Ser-|-His-34', '35-Leu-|-Val-36', '40-Tyr-|-Leu-41', '41-Leu-|-Val-42', '42-Val-|-Cys-43', '43-Cys-|-Gly-44', '44-Gly-|-Glu-45', '46-Arg-|-Gly-47', '47-Gly-|-Phe-48', '49-Phe-|-Tyr-50' and '52-Pro-|-Lys-53' bonds. Also cleaves human prothrombin (72 kDa) and activation fragment F1 (27 kDa) of activated human prothrombin, to generate two new proteins of 68 and 23 kDa. Binds 1 zinc ion per subunit. Its proteolytic and hemorrhagic activities are inhibited by EDTA, but not by PMSF. Monomer. Expressed by the venom gland. The N-terminus is blocked. Does not activate human prothrombin. The disintegrin domain belongs to the long disintegrin subfamily. Belongs to the venom metalloproteinase (M12B) family. P-III subfamily. P-IIIa sub-subfamily.