Plays a role in the generation of neuronal polarity formation and axon growth. Implicated in the formation of a single axon by developing neurons. May inhibit the formation of additional axons by inhibition of PI3K in minor neuronal processes. Plays a role in the formation of F-actin-enriched protrusive structures at the cell periphery. Plays a role in cytoskeletal organization by regulating the subcellular localization of FSCN1 and DBN1 at axonal growth cones. Promotes gastric cancer cell migration and invasion in a PAK1-dependent manner. Interacts with PAK1. Interacts (via C-terminus) with Ras-related Rab-5 proteins. Interacts (via C-terminus) with Ras-related Rap-2 proteins. Interacts with PIK3CA and PIK3R1. Interacts (via N-terminus) with FSCN1; this interaction induces neuron axon development. Interacts with DBN1. Colocalizes with PAK1, F-actin, myosins and integrins in invadopodia at the cell periphery. Colocalized with Ras-related Rab-5 proteins in cytoplasmic vesicles. Accumulates in axon growth cones in a F-actin-dependent manner. Colocalized with FSCN1 and F-actin at filipodia and lamellipodia of axonal growth cones. Colocalized with DBN1 and F-actin at transitional domain of the axonal growth cone. Phosphorylated by PAK1.