Enzyme of the diterpenoid metabolism involved in the biosynthesis of the oryzalexin class of phytoalexins. Hydroxylates ent-sandaracopimaradien. ent-sandaracopimaradien-3beta-ol + O2 + reduced [NADPH--hemoprotein reductase] = H(+) + H2O + oryzalexin E + oxidized [NADPH--hemoprotein reductase] Up-regulated by methyl jasmonate. Belongs to the cytochrome P450 family.