Small GTP-binding protein which cycles between an inactive GDP-bound and an active GTP-bound form, and the rate of cycling is regulated by guanine nucleotide exchange factors (GEF) and GTPase-activating proteins (GAP). GTP-binding protein that does not act as an allosteric activator of the cholera toxin catalytic subunit. Recruits CYTH1, CYTH2, CYTH3 and CYTH4 to the plasma membrane in GDP-bound form (By similarity). Interacts with CYTH2. Interacts with KPNA2; the interaction is direct. Does not interacts with ARL4A (By similarity). Localization in the nucleolus is dependent by nucleotide binding. Myristoylated. Belongs to the small GTPase superfamily. Arf family.