Probably has no catalytic activity due to the loss of several residues required for processing and catalysis (PubMed:17485680). Forms a complex with S-adenosylmethionine decarboxylase AdoMetDC which is essential to activate AdoMetDC (PubMed:17485680, PubMed:18949025). Required for the biosynthesis of the polyamine spermidine (PubMed:18949025). Required for growth and survival during the bloodstream life cycle stage (PubMed:18949025). Amine and polyamine biosynthesis; S-adenosylmethioninamine biosynthesis; S-adenosylmethioninamine from S-adenosyl-L-methionine: step 1/1. Forms a heterodimer with S-adenosylmethionine decarboxylase AdoMetDC; heterodimerization is required to activate AdoMetDC. Expressed during both bloodstream (BF) and procyclic insect (PF) life cycle stages. RNAi-mediated knockdown at the bloodstream life cycle stage causes cell growth arrest followed by death. Putrescine levels are increased and the production of spermidine, glutathione, glutathionyl-spermidine and trypanothione is severely reduced. In addition, protein expression levels of ornithine carboxylase (ODC) are increased. Belongs to the eukaryotic AdoMetDC family.