Acts as a negative regulator of cell migration, invasion, and metastasis downstream of p53/TP53, through inhibition of Arp2/3 complex-mediated actin polymerization (By similarity). Via its association with the multisubunit axonemal dynein complex, is potentially involved in the regulation of cilia function (PubMed:30060180). May play a role in osteogenesis of dental tissue-derived mesenchymal stem cells (PubMed:25498833). Interacts with ACTR2; this interaction reduces binding of the Arp2/3 complex to the VCA domain of nucleation promoting factors (By similarity). Part of the multisubunit axonemal dynein complex formed at least of two heavy chains and a number of intermediate and light chains (PubMed:30060180). Found in a associated with the catalytic heavy chain DNAH2, the intermediate chain DNAI4, and the light chain DYNLT1 (PubMed:30060180). Strongly expressed in the testes (PubMed:26501274). Detected also in brain and lung tissues (PubMed:26501274). Deficient mice shown no overt abnormalities in body size, development, behavior, or fertility.