MFS-type efflux pump involved in the modulation susceptibility to various compounds including cumyl hydroperoxide, potassium superoxide, many singlet oxygen-generating compounds (eosin Y, rose Bengal, hematoporphyrin, methylene blue, and cercosporin), and the cell wall biosynthesis inhibitor Congo red (PubMed:28060864). Involved in oxidative stress tolerance, colonization, and lesion formation (PubMed:28060864). Expression is regulated by the Yap1 transcription activator, the Hog1 and Fus3 mitogen-activated protein (MAP) kinases, the two component histidine kinase, and the Skn7 response regulator. Displays profound hypersensitivities to cumyl hydroperoxide, potassium superoxide, many singlet oxygen-generating compounds (eosin Y, rose Bengal, hematoporphyrin, methylene blue, and cercosporin), and the cell wall biosynthesis inhibitor, Congo red (PubMed:28060864). Also increases sensitivity to copper ions, clotrimazole, fludioxonil, and kocide fungicides, 2-chloro-5-hydroxypyridine (CHP), and 2,3,5-triiodobenzoic acid (TIBA) (PubMed:28060864). Leads to smaller necrotic lesions on leaves of a susceptible citrus cultivar (PubMed:28060864). Belongs to the major facilitator superfamily.