Multidrug resistance transporter involved in resistance to the antifungal drugs miconazole, tioconazole, clotrimazole, and ketoconazole; as well as to quinidine (PubMed:23629708, PubMed:27148215). Decreases the intracellular accumulation of clotrimazole in and plays a role in the extrusion of this antifungal from preloaded cells (PubMed:23629708, PubMed:27148215). Expression is up-regulated by clotrimazole and quinidine (PubMed:23629708). Expression is regulated by the pleiotropic drug resistance transcription factor PDR1 (PubMed:23629708). Leads to intracellular accumulation of clotrimazole (PubMed:23629708). Belongs to the major facilitator superfamily. CAR1 family.