chorismate = prephenate NAD(+) + prephenate = 3-(4-hydroxyphenyl)pyruvate + CO2 + NADH Amino-acid biosynthesis; L-tyrosine biosynthesis; (4-hydroxyphenyl)pyruvate from prephenate (NAD(+) route): step 1/1. Metabolic intermediate biosynthesis; prephenate biosynthesis; prephenate from chorismate: step 1/1. In the C-terminal section; belongs to the prephenate/arogenate dehydrogenase family.