Required for proper function of the olfactory system. May be involved in establishing the acuity of olfactory sensory signaling. Specifically expressed in the olfactory epithelium and vomeronasal organ throughout development. Expressed in both immature and mature olfactory sensory neurons in the olfactory epithelium (at protein level). First expressed at embryonic day (E) 11.5 in the olfactory epithelium and at 13.5 dpc in the vomeronasal organ. Expression increases thereafter, reached maximal level at P14, and strong expression level is maintained into adulthood. Various olfactory phenotypes, such as abnormal localization of ADCY3, shortened olfactory cilia, and reduced electrophysiological and behavioral sensitivities to odorants.