Catalyzes both the decarboxylative condensation of pimeloyl-[acyl-carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide, and the transformation of pimelate into pimeloyl-CoA with concomitant hydrolysis of ATP to AMP. ATP + CoA + heptanedioate = 6-carboxyhexanoyl-CoA + AMP + diphosphate 6-carboxyhexanoyl-[ACP] + H(+) + L-alanine = (8S)-8-amino-7-oxononanoate + CO2 + holo-[ACP] Metabolic intermediate metabolism; pimeloyl-CoA biosynthesis; pimeloyl-CoA from pimelate: step 1/1. Cofactor biosynthesis; biotin biosynthesis. Homodimer. In the N-terminal section; belongs to the BioW family. In the C-terminal section; belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. BioF subfamily.