Plays a role in melanin biosynthesis. Catalyzes the conversion of L-dopachrome into 5,6-dihydroxyindole-2-carboxylic acid (DHICA). L-dopachrome = 5,6-dihydroxyindole-2-carboxylate Binds 2 Zn(2+) ions per subunit. Pigment biosynthesis; melanin biosynthesis. Proper trafficking to melanosome is regulated by SGSM2, ANKRD27, RAB9A, RAB32 and RAB38. Melanocytes and retinal pigmented epithelium. Belongs to the tyrosinase family.