Required for normal morphology of late endosomes and/or lysosomes in neurons (By similarity). Binds phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P2). Forms a complex with clathrin heavy chain and gamma-adaptin. Expressed mainly in the brain. The CRAL-TRIO domain is required for targeting to the membrane and for binding PtdIns(3,5)P2. Binding to PtdIns(3,5)P2 is not required for localization. May be due to an intron retention.