Cleaves C-terminal amino acids linked to proline in peptides such as angiotensin II, III and des-Arg9-bradykinin. This cleavage occurs at acidic pH, but enzymatic activity is retained with some substrates at neutral pH. Cleavage of a -Pro-|-Xaa bond to release a C-terminal amino acid. Homodimer. Highest levels in placenta, lung and liver. Also present in heart, brain, pancreas and kidney. Belongs to the peptidase S28 family.