Nucleic acid-binding protein which is essential for retrotransposition of LINE-1 elements in the genome. Functions as a nucleic acid chaperone binding its own transcript and therefore preferentially mobilizing the transcript from which they are encoded. Homotrimer (via coiled coil domain). May also form larger homooligomers. Interacts with Tex19.1 and UBR2 (PubMed:28806172). Interacts with MOV10 (PubMed:28662698). Colocalizes with its encoding RNA in cytoplasmic ribonucleoprotein particle. Mainly cytoplasmic, rarely detected in the nucleus, possibly within the nucleolus. Expressed in meiotic spermatocytes and in the cerebellum (at protein level). The coiled coil domain mediates homotrimerization. The RRM and the CTD domain are both required for proper RNA-binding activity. Polyubiquitinated, probably by UBR2, which induces its degradation. An active LINE-1 encodes for 2 proteins translated from a single RNA containing two non-overlapping ORFs, ORF1 and ORF2. ORF1p is described in that entry as a representative of all ORF1p potentially expressed by active elements in mouse genome. ORF2p is described in the related entry AC P11369. Belongs to the transposase 22 family.