Destroys radicals which are normally produced within the cells and which are toxic to biological systems (PubMed:16524904, PubMed:12496163). Destroys radicals produced by host defense mechanisms (PubMed:12496163). 2 H(+) + 2 superoxide = H2O2 + O2 Binds 1 copper ion per subunit. Binds 1 zinc ion per subunit. Homodimer. Localizes to lipid rafts in the cell membrane. Repressed when copper levels are low in a CUF1-dependent manner (at protein level) (PubMed:33567338). Induced by high temperature (PubMed:12496163). Decreases cellular superoxide dismutase activity (PubMed:16524904). Sensitive to oxygen radicals (PubMed:12496163). Decreases virulence in a mouse inhalation model of infection (PubMed:12496163). Belongs to the Cu-Zn superoxide dismutase family.