Involved in the biosynthesis of the macrolide antibiotic tylosin derived from the polyketide lactone tylactone. TylM3 is required for the glycosylation of the 5-hydroxyl group of tylactone to yield 5-O-mycaminosytylactone. Antibiotic biosynthesis; tylosin biosynthesis. Belongs to the cytochrome P450 family. Although TylM3 shows significant similarity to cytochrome P450 family, it lacks the heme-binding sites. The conservation of amino acid sequence is confined primarily to the C-terminal half of the protein.