Binds to regulatory subunit (RII) of protein kinase A. May be involved in establishing polarity in signaling systems or in integrating PKA-RII isoforms with downstream effectors to capture, amplify and focus diffuse, trans-cellular signals carried by cAMP (By similarity). The RII-alpha binding site, predicted to form an amphipathic helix, could participate in protein-protein interactions with a complementary surface on the R-subunit dimer. Based on a naturally occurring readthrough transcript which produces a PALM2-AKAP2 fusion protein. Based on a naturally occurring readthrough transcript which produces a PALM2-AKAP2 fusion protein.