Bifunctional enzyme that possesses cyclase and dehydrogenase activities (PubMed:30531909, PubMed:30664302). Functions as a non-oxidoreductive cyclase to promote the formation of cis-trans-nepetalactol (PubMed:30531909, PubMed:30664302). Functions as dehydrogenase to oxidize cis-cis-nepetalactol and cis-trans-nepetalactol into nepetalactones, metabolites that are both insect-repellent and have euphoric effect in cats (PubMed:30531909, PubMed:30664302). Binds NAD(+) as classical short-chain dehydrogenase/reductase (SDR), but does not utilize it for its redox-neutral cyclase activity (By similarity). (S)-8-oxocitronellyl enol = cis-trans-nepetalactol cis-cis-nepetalactol + NAD(+) = cis-cis-nepetalactone + H(+) + NADH cis-trans-nepetalactol + NAD(+) = cis-trans-nepetalactone + H(+) + NADH kcat is 0.148 sec(-1) with cis-trans-nepetalactol as substrate (in the presence of NAD(+) at pH 8.0 and 25 degrees Celsius). kcat is 0.32 sec(-1) with cis-cis-nepetalactol as substrate (in the presence of NAD(+) at pH 8.0 and 25 degrees Celsius). kcat is 0.173 sec(-1) with NAD(+) as substrate (in the presence of cis-trans-nepetalactol at pH 8.0 and 25 degrees Celsius). Belongs to the short-chain dehydrogenases/reductases (SDR) family.