Plays an important role in the degradation of dermatan and keratan sulfates. a beta-D-glucuronoside + H2O = an alcohol + D-glucuronate Inhibited by L-aspartic acid. Homotetramer. N-linked glycosylated with 3 to 4 oligosaccharide chains. The disease is caused by variants affecting the gene represented in this entry. Belongs to the glycosyl hydrolase 2 family.