Endocytosed from the cell surface, thus entered into early endosomes, trafficks to late endosomes and degradates in lysosomes (By similarity). Mainly Golgi stack, but also found in small vacuolar organelles and multivesicular bodies (PubMed:7829526). Found in both stationary and motile endosomes (PubMed:28874679). Specifically expressed in neural and neuroendocrine tissues. Pituitary and less in adrenal gland and testis. Expressed in the hippocampus throughout development. Remains enriched in layer V cortical neurons during development. At P0, broadly expressed in the neocortex. Is down-regulated overall at P8 and P14, but remains relatively enriched in layer V. At P0 is lower expressed in the cerebellum. Expression remains low throughout development, and is undetectable by adulthood (PubMed:28299779). Highly expressed at 20 dpc. At 17.5 dpc, highly expressed in the cortical plate and basal subventricular zone. Belongs to the NSG family.