Anchors the catalytic subunits of asymmetric AChE to the synaptic basal lamina. Homotrimer. Component of the asymmetric form of AChE, a disulfide-bonded oligomer composed of the collagenic subunits (Q) and a variable number of asymmetric catalytic subunits (T). The N-terminal of a collagenic subunit (Q) associates with the C-terminal of a catalytic subunit (T). Expressed in skeletal muscle, heart, brain, as well as in lung, spleen, testis, but not liver. The short isoform represents about 5% of the transcripts in the soleus muscle and about 15% in the heart ventricle. The proline-rich attachment domain (PRAD) binds the AChE catalytic subunits. The triple-helical tail is stabilized by disulfide bonds at each end. Belongs to the COLQ family.