Alpha-conotoxins act on postsynaptic membranes, they bind to the nicotinic acetylcholine receptors (nAChR) and thus inhibit them. This toxin specifically blocks mammalian neuronal nAChR of the alpha-7/CHRNA7, alpha-3-beta-2/CHRNA3-CHRNB2 and alpha-4-beta-2/CHRNA4-CHRNB2 subtypes (By similarity). Hetero-, homo- or pseudo-homodimers (identical sequence, different post-translational modifications) (By similarity). Heterodimer of [carboxy'Glu-49', hydroxy'Pro-55']Ms20.3 and [carboxyGlu-50, hydroxyPro-56]Ms20.5 may exist. Expressed by the venom duct. The cysteine framework is XX (C-CC-C-CC-C-C-C-C). Contains 5 disulfide bonds. Belongs to the conotoxin D superfamily.