In neurons, plays a role in the regulation of intracellular Ca(2+), possibly by acting as an activator of ATP2A2/SERCA2, thus increasing the efficiency with which Ca(2+) is removed from the cytoplasm (PubMed:35036403). Inhibits differentiation of embryonic stem cells into neurons and inhibits neurite outgrowth, likely as a result of its role in intracellular Ca(2+) regulation (PubMed:35036403). In pancreatic beta cells, lowers Ca(2+) levels in the endoplasmic reticulum and enhances glucose-stimulated insulin secretion (By similarity). Interacts with ATPase ATP2A2/SERCA2 (PubMed:35036403). Interacts with ATPase ATP2A3/SERCA3; the interaction occurs at low levels in low glucose conditions and is increased by high glucose levels (By similarity). In the adult, expressed in Purkinje cells in the cerebellum, in motor neurons and interneurons in the spinal cord and in neurons of the cortex, hippocampus and thalamus (at protein level) (PubMed:35036403). Also detected in the developing cortex, hippocampus and thalamus at embryonic day E15.5 (at protein level) (PubMed:35036403).