Cytochrome P450 catalyzing the monooxygenation of 16-methoxytabersonine, 16-hydroxytabersonine and tabersonine, but not of 2,3-dihydrotabersonine (PubMed:25918424). Converts the C2,C3 alkene of tabersonine and 16-methoxytabersonine to the epoxides, which then spontaneously open to form the corresponding imine alcohols (PubMed:25850027). Inactive in converting amyrin to ursolic acid (PubMed:22837051). 16-methoxytabersonine + O2 + reduced [NADPH--hemoprotein reductase] = (3R)-1,2-didehydro-3-hydroxy-16-methoxy-2,3-dihydrotabersonine + H(+) + H2O + oxidized [NADPH--hemoprotein reductase] (-)-tabersonine + O2 + reduced [NADPH--hemoprotein reductase] = (3R)-1,2-didehydro-3-hydroxy-2,3-dihydrotabersonine + H(+) + H2O + oxidized [NADPH--hemoprotein reductase] The KM is mesured in the presence of a saturating amount of tabersonine 3-reductase, the enzyme converting the unstable intermediate produced by the reaction. Alkaloid biosynthesis; vindoline biosynthesis. Expressed in leaf epidermis. Up-regulated by herbivory. The CYP71D1V2 product is either trapped by the reductase T3R to form vindorosine and vindoline precursors, or it spontaneously rearranges to form a member of the eburnamine class of monoterpene indole alkaloids. Belongs to the cytochrome P450 family.