Transcription factor. Binds optimally to the DNA consensus sequence 5'-YYTAATGRTTTTY-3'. May control the expression of neural adhesion molecules such as L1 or Ng-CAM during embryonic development of both the central and peripherical nervous system. May be involved in controlling adhesive processes in keratinizing epithelia. Nervous system, particularly in the telencephalon, spinal cord, and dorsal root ganglia. Highly expressed in small groups of cells undergoing tissue remodeling, such as ectodermal cells within indentations surrounding the eye and maxillo-nasal groove and in the first branchial pouch, lung buds, precartilagenous condensations, and mesenchyme of the limb. At 9.5 dpc, expressed only to head, prominent in the region of telencephalon and mesencephalon, and concentrated in cells along the dorsal midline. At 10.5 dpc, expression is moderated in the most rostral regions of the head, but particularly prominent in a lateral band of cells in the periocular region. At 11.5 dpc, detected in the telencephalon, frontonasal region and limbs. At 12.5 dpc, expressed in the telencephalon and hindbrain. Belongs to the BAR homeobox family.