May play a role in the regulation of cilium length. Stabilizes microtubules at low temperature. Associates with microtubules via the Mn regions. In multi-ciliated cells, localizes to the basal bodies and in non-ciliated cells, to the centrosome. In spermatozoa, colocalizes with microtubules along the length of the axoneme from its proximal end to its distal tip and with tubulin at the distal end of the flagellum and at the proximal centriole. The Mn regions are involved in microtubule-binding and stabilization at low temperature. They are required and sufficient for cilium targeting. The N-terminal region (residues 1-29) might play a role in centriole retention. Belongs to the FAM154 family.