Catalyzes the hydrolysis of acyl-CoAs into free fatty acids and coenzyme A (CoASH), regulating their respective intracellular levels. Catalyzes the hydrolysis of phytanoyl-CoA and pristanoyl-CoA, two methyl-branched fatty acids derived from phytol, that enter the body via the diet. H2O + pristanoyl-CoA = 2,6,10,14-tetramethylpentadecanoate + CoA + H(+) H2O + phytanoyl-CoA = 3,7,11,15-tetramethylhexadecanoate + CoA + H(+) Lipid metabolism; fatty acid metabolism. Highly expressed in white adipose tissue. Detected at lower levels in kidney, liver, brown adipose tissue and brain. Up-regulated in liver upon treatment with peroxisome proliferator. Belongs to the C/M/P thioester hydrolase family. Truncated N-terminus. Contaminating sequence. Small insertion of unknown origin.