Regulates the morphogenesis and endocytosis of caveolae (By similarity). Lipid-binding protein that is able to promote the tubulation of the phosphatidic acid-containing membranes it preferentially binds. Plays a role in intracellular vesicle-mediated transport. Involved in the endocytosis of cell-surface receptors like the EGF receptor, contributing to its internalization in the absence of EGF stimulus. Interacts with adam13 through the SH3 domains. Detected at the neck of flask-shaped caveolae. Ubiquitously expressed with higher expression in the ectoderm, the neuroectoderm, and dorsal mesoderm layers. Expressed in two-cell stage, early blastula, early gastrula, early neurula and early and late tail bud stages. The F-BAR domain forms a coiled coil and mediates membrane-binding and membrane tubulation (By similarity). Autoinhibition of these functions is mediated by an interaction between the SH3 and F-BAR domains (By similarity). The F-Bar domain also mediates the binding to the cell actin cytoskeleton through the interaction with CAV-1 (By similarity). Phosphorylated. Belongs to the PACSIN family.