Plays a role in constitutive splicing and can modulate the selection of alternative splice sites. Represses the splicing of MAPT/Tau exon 10 (By similarity). Interacts with KHDRBS3. Interacts with HABP4. Interacts with NOL3/ARC/NOP30. Interacts with NSEP1/YB-1/YB1. Interacts with SAFB/SAFB1. Interacts with SRSF6/SFRS6. Interacts with TRA2B/SFRS10. Interacts with C1QBP. May also interact with DUSP11/PIR1. Extensively phosphorylated on serine residues in the RS domain. Belongs to the splicing factor SR family.