Induces host cell lysis. Inhibits the host translocase MraY activity that catalyzes the synthesis of lipid I, a necessary step for the host cell wall biosynthesis. Oligomerizes. Interacts (via N-terminal) with host SlyD; this interaction supposely protects E from proteolysis and therefore allows E to interact with and inhibit host MraY at the host membrane. Interacts with host MraY; this interaction inhibits MraY translocase activity. Belongs to the microvirus E protein family.