Interacts with PIK3R/p85, SHP2 and GRAP2/MONA. May interact with Grb2. Highly expressed in spleen and thymus and weakly in brain, heart, lung, kidney, uterus, and embryonic stem cells. Also expressed in myeloid and macrophage cell lines. Phosphorylated on tyrosine residue(s) after macrophage colony-stimulating factor (M-CSF) receptor stimulation. Belongs to the GAB family.