Promotes degradation of target mRNA species. Plays a role in the regulation of circadian mRNA stability. Binds GTP and has GTPase activity (By similarity). Interacts with EXOSC2/RRP4, EXOSC3/RRP40, EXOSC5/RRP46, HNRNPD, HNRNPR and SYNCRIP. Identified in a complex with AANAT mRNA, but does not bind mRNA by itself (By similarity). Detected in some neurons in the brain cortex. Detected in small arteries, dendritic cells and macrophages in the thymus. Detected in lung bronchi, in bronchial epithelial cells and in bronchial smooth muscle cells. Detected in smooth muscle cells in a broad range of organs (at protein level). Expressed in brain, thymus, lung, and kidney. No visible phenotype. Mice are born at the expected Mendelian ratio, develop normally and are fertile. They exhibit increased stability of some mRNA species. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. GTPBP1 subfamily.