Small GTPase that negatively regulates a MAP kinase branch, downstream of SLT2, of the PKC1-mediated signal transduction pathway (PubMed:12118069). With its specific guanine nucleotide exchange factor (GEF), the heterodimeric complex DCK1/LMO1, relocates to mitochondria upon oxidative stress and triggers cell death (PubMed:25598154). The DCK1/LMO1/RHO5 signaling module that mediates mitochondrial turnover under nitrogen starvation conditions via mitophagy (PubMed:25598154). The DCK1/LMO1/RHO5 signaling module also plays a role in cell wall integrity signaling (PubMed:25598154). Interacts with RGD2. Localization to mitochondria occurs upon oxidative stress and is dependent of DCK1 and LMO1. Leads to resistance to oxidants such as H(2)O(2) (PubMed:25598154). Impairs apoptotic phenotype after H(2)O(2) treatment (PubMed:25598154). Leads to hyper-resistance to cell wall stress agents such as calcofluor white and Congo red (PubMed:25598154). Present with 2180 molecules/cell in log phase SD medium. Belongs to the small GTPase superfamily. Rho family.