Involved in neutrophil activation. In vitro, ENA-78(8-78) and ENA-78(9-78) show a threefold higher chemotactic activity for neutrophil granulocytes. Monomer (PubMed:24695525). Homodimer (PubMed:24695525). N-terminal processed forms ENA-78(8-78) and ENA-78(9-78) are produced by proteolytic cleavage after secretion from peripheral blood monocytes. Belongs to the intercrine alpha (chemokine CxC) family. CXCL5 entry