Component of the SKI complex which is thought to be involved in exosome-mediated RNA decay and associates with transcriptionally active genes in a manner dependent on PAF1 complex (PAF1C). Component of the SKI complex which consists of WDR61, SKIV2L and TTC37. Interacts with PAF1. Widely expressed with the highest levels observed in vascular tissues, lymph node, pituitary, lung and intestine. Not expressed in the liver. The disease is caused by variants affecting the gene represented in this entry. Extended N-terminus.