May play a role in the developmental transition from cell proliferation to cell differentiation during neurogenesis. Expressed in developing retina and brain, but not in heart, liver or kidney. In brain, located in a narrow strip in the boundary between the ventricular zone (consisting of proliferating cells) and the intermediate zone (consisting of postmitotic, differentiating cells). Expressed in all major regions of the developing brain, including the myelencephalon, the mesencephalon, the telencephalon and the diencephalon. In the developing retina, expression is scattered across the retinal neural epithelium (PubMed:9514522). Expressed in egg white (at protein level). Expressed in the magnum of the oviduct (at protein level) (PubMed:25436390). In brain, not abundant during the early stages of neurogenesis. Expression increases during cytogenesis followed by a rapid decrease towards the end of cytogenesis. Undetectable at E16. In retina, expression is detected at E4 and E6, and becomes scarce by E8. Not detected in the mature retina. Down-regulated by dietary stress. Significantly decreased expression between days 0 to 5 in egg whites of eggs laid by corticosterone-fed hens (at protein level). Decreased expression at day 14 in the magnum of the oviduct in the corticosterone-fed laying hens.