Facilitates DNA repair, cell cycle progression, and cell proliferation through its interaction with CIAO2B. Interacts with CIAO2B; the interaction is direct. Interacts with MMS19; the interaction is indirect. Mitotic spindle. Firstly detected at E8.5 in pharyngeal arch regions, particularly in the first arch, and in developing outflow tract (OFT) regions. Expression continued through E9.5 in the cardiac outflow tract and atria, and in second heart field (SHF)-containing pharyngeal arch with additional expression in lower craniofacial regions. Also expressed in the developing outflow tract and SHF-associated pharyngeal mesoderm, with additional expression observed in pharyngeal endoderm, outflow tract endocardium and ventral neural tube populations.