Regulates the mitochondrial network by promoting mitochondrial fission. Homodimer. Expressed in brain, spinal cord, muscles and intestinal villi. In the central nervous system expressed most prominently in the cortex, cerebellum, thalamus, olfactory bulb, and spinal cord. Expressed also in sciatic nerves and in dorsal root ganglia. First expressed at embryonic stage 13 dpc. Levels then increase gradually to reach maximum levels at adulthood. Increased expression during neural differentiation. Ubiquitinated by PRKN during mitophagy, leading to its degradation and enhancement of mitophagy. Deubiquitinated by USP30. Belongs to the GST superfamily. While belonging to the GST superfamily, it lacks glutathione transferase activity.