H2O + L-glutamate + NAD(+) = 2-oxoglutarate + H(+) + NADH + NH4(+) H2O + L-glutamate + NADP(+) = 2-oxoglutarate + H(+) + NADPH + NH4(+) Homohexamer. Belongs to the Glu/Leu/Phe/Val dehydrogenases family.