Component of the cul4-rbx1-ddb1-dcaf1 E3 ubiquitin-protein ligase complex, dcaf1 may function as the substrate recognition module within this complex. Protein modification; protein ubiquitination. Component of the cul4-rbx1-ddb1-dcaf1 E3 ubiquitin-protein ligase complex. The DWD boxes are required for interaction with ddb1. Belongs to the VPRBP/DCAF1 family.