Expressed in prostate and testis. A chromosomal aberration involving BCL8 has been observed in diffuse large cell lymphoma (DLCL). Translocation t(14;15)(q32;q11-q13). The BCL8/IgH translocation leaves the coding region of BCL8 intact, but may have pathogenic effects due to alterations in the expression level of BCL8. Could be the product of a pseudogene.