Involved in the biosynthesis of labdane-type diterpenoid including cleroda-dienols, and peregrinol lactones and furan derivatives, dopaminergic diterpenoids that can bind to dopamine receptors in the human pituitary gland, have probably ability to lower prolactin levels, and are used to treat menstrual cycle disorders (e.g. premenstrual syndrome and mastodynia) (Probable). Cytochrome P450 catalyzing the hydroxylation of peregrinol to form labd-13Z-ene-9,15,16-triol (PubMed:29315936). O2 + peregrinol + reduced [NADPH--hemoprotein reductase] = H(+) + H2O + labd-13Z-ene-9,15,16-triol + oxidized [NADPH--hemoprotein reductase] Secondary metabolite biosynthesis; terpenoid biosynthesis. Mostly expressed in trichomes of leaves and fruits. Belongs to the cytochrome P450 family.