Type II acute-phase protein (APP) involved in inflammatory responses to trauma. May also play a role in liver development or regeneration. Interacts (via C-terminus) with DNAJC1 (via SANT 2 domain). Highly expressed in liver. Weak expression in lung and heart. During mid-embryonic gestation, expressed abundantly in liver, less in heart and brain. Highest expression at day 14.5. May be O-glycosylated (By similarity). N-glycosylated. Belongs to the ITIH family.