Inactive effector protein: in contrast to other members of the family, does not have the ability to inhibit host cell NF-kappa-B activation (PubMed:20485572). Probably lacks cysteine S-methyltransferase activity due to its inability to bind S-adenosyl-L-methionine at the C-terminus (Probable). Secreted via the type III secretion system (TTSS) (PubMed:17984206). Mainly localizes in the cytoplasm of the infected cells, and occasionaly in the host nucleus (PubMed:17984206). Belongs to the NleE/OspZ family. Probable inactive cysteine methyltransferase. In contrast to other members of the family, has a shorter C-terminus and is unable to inhibit host cell NF-kappa-B activation (PubMed:20485572). Extended N-terminus.