Promotes cholesterol efflux from sperm which renders sperm capable of fertilization. Has also been shown to decrease levels of intracellular esterified neutral lipids including cholesteryl esters, fatty acid esters and triacylglycerols. ATP + cholesterol(in) + H2O = ADP + cholesterol(out) + H(+) + phosphate N-glycosylated. Belongs to the ABC transporter superfamily. ABCA family.