Catalyzes the hydrolytic deamination of adenosine. Plays an important role in purine metabolism and in adenosine homeostasis, and may thereby contribute to cellular signaling events (By similarity). adenosine + H(+) + H2O = inosine + NH4(+) Binds 1 zinc ion per subunit. Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family.