Involved in storage lipid mobilization during the growth of higher plant seedling. D-threo-isocitrate = glyoxylate + succinate Carbohydrate metabolism; glyoxylate cycle; (S)-malate from isocitrate: step 1/2. Homotetramer. Belongs to the isocitrate lyase/PEP mutase superfamily. Isocitrate lyase family.