Vacuolar serine-type carboxypeptidase involved in vacuolar zymogen activation, breakdown of the autophagic body, and autophagosome-dependent protein synthesis (PubMed:29514932). Plays a key role in phytochelatin (PC) synthesis from glutathione (GSH) by cleaving the Gly from GSH and form the PC-peptides of the structure (gamma-Glu-Cys)2-Gly (PubMed:17408619). Also involved in resistance to xenobiotics via the degradation of glutathione-S-conjugates (PubMed:19897216). Release of a C-terminal amino acid with broad specificity. The vacuolar sorting receptor VPS10 is required for the delivery of ATG42 to the vacuole lumen. Expression is induced by nitrogen limitation in a GLN3 and GAT1-independent manner. Leads to vacuolar defects as well as defects in the terminal steps of autophagy, when PCR1 is also deleted (PubMed:29514932). The PCR1/ATG42 double deletion abrogates also the production ofphytochelatin and the degradation of glutathione-S-conjugates (PubMed:17408619, PubMed:19897216). Present with 1420 molecules/cell in log phase SD medium. Belongs to the peptidase S10 family.