Mono-ADP-ribosylates chicken skeletal alpha-actin and human non-skeletal beta- and gamma-actin. Mono-ADP-ribosylates 'Arg-177' of yeast actin, blocking its ability to polymerize. Does not possess NAD(+)-glycohydrolase activity, unlike most mART enzymes. Upon expression in S.cerevisiae almost completely inhibits growth. L-arginyl-[protein] + NAD(+) = H(+) + N(omega)-(ADP-D-ribosyl)-L-arginyl-[protein] + nicotinamide Measured on chicken skeletal alpha-actin. In the C-terminal section; belongs to the SpvB family.