Receptor for melanin-concentrating hormone, coupled to both G proteins that inhibit adenylyl cyclase and G proteins that activate phosphoinositide hydrolysis. Interacts with NCDN. Highest level in brain, particularly in the frontal cortex and hypothalamus, lower levels in the liver and heart. Belongs to the G-protein coupled receptor 1 family. It is uncertain whether Met-1, Met-6 or Met-70 is the initiator.