Acts as a ligand for the npr-22 receptor and controls food-related processes including feeding, lifespan, egg-laying and roaming behavior. Secreted in the presence of food, leading to reduced feeding and roaming behavior and increased egg laying and lifespan. Activity may be latent under normal conditions but induced under conditions that cause hyperactivation of the pharynx such as abrupt refeeding after starvation. Acts as a ligand for the npr-22 receptor and controls food-related processes including feeding, lifespan, egg-laying and roaming behavior. Secreted in the presence of food, leading to reduced feeding and roaming behavior and increased egg laying and lifespan. Activity may be latent under normal conditions but induced under conditions that cause hyperactivation of the pharynx such as abrupt refeeding after starvation. Secreted from the M1 and M2 pharyngeal neurons in a food-dependent manner with secretion positively controlled by the presence of food. Secreted from the M1 and M2 pharyngeal neurons in a food-dependent manner with secretion positively controlled by the presence of food. Expressed in the M1 and M2 pharyngeal neurons from where the LURY-1-1 and LURY-1-2 peptides are secreted. In the M1 pharyngeal neuron, expressed in all larval stages and in adults. In the M2 pharyngeal neuron, expression is not detected in most L1-L3 larva but increases at the L4 larval stage. Eggs are retained in the body as normal during starvation but the number of eggs laid during the initial refeeding period is reduced and satiety-induced suppression of pharyngeal pumping is slower than wild-type.