By itself the v-Mil oncogene has only weak transforming capacity but it abolishes the growth factor requirements of avian macrophages transformed by other oncogenes. ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein] ATP + L-threonyl-[protein] = ADP + H(+) + O-phospho-L-threonyl-[protein] This protein is synthesized as a Gag-Mht or Gag-Mil polyprotein. Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. RAF subfamily.