DSP may be an important factor in dentinogenesis. DPP may bind high amount of calcium and facilitate initial mineralization of dentin matrix collagen as well as regulate the size and shape of the crystals. Interacts with FBLN7. Specifically expressed in teeth, mainly in odontoblasts and transiently in pre-ameloblasts. Down-regulated by the CEBPB-NFE2L1 heterodimer during odontoblast differentiation. DSP is glycosylated.