May mediate cellular response to DNA damage by protecting against ultraviolet C-induced cell death (By similarity). Can form voltage-gated calcium and potassium channels in vitro (PubMed:21381722). Homooligomer (PubMed:21381722). Interacts with CRYAB (By similarity). Widely expressed. Expressed in skeletal, cardiac and smooth muscle cells, in brain, including neuroglial cells, cerebral cortex neurons and cerebellum, but not Purkinje cells. Also detected in Paneth and Goblet cells of the small intestine (but not in the epithelium), duodenal gland, pancreas, parotid gland, testis, thyroid gland and adrenal gland, as well as in epidermis, choroid plexus, ductus epididymidis, lymphocytes, fibroblasts, endothelial cells and seminiferous epithelial cells (at protein level). Not detected in mucous cells of the duodenal gland, in hepatocytes nor in uriniferous tubules. The N-terminus is blocked.