The hemorrhagic metalloproteinase-disintegrin-like bothrojarin-1 is a potent inhibitor of collagen-induced platelet aggregation by blockage of alpha-2/beta-1 (ITGA2/ITGB1) integrin. It does not present any fibrinogen-clotting activity (By similarity). Binds 1 zinc ion per subunit. Monomer. Expressed by the venom gland. Belongs to the venom metalloproteinase (M12B) family. P-III subfamily. P-IIIa sub-subfamily.