Has strong antibacterial activity and biofilm inhibition effects against Gram-positive and -negative bacteria including E.coli, S.epidermidis, and A.baumannii and oxacillin-resistant S.aureus and meropenem-resistant P.aeruginosa (PubMed:27128941, PubMed:34506798). Is not cytotoxic against human foreskin fibroblast Hs27 or hemolytic against mammalian red blood cells (PubMed:27128941, PubMed:34506798). Its mechanism of action involves binding to lipoteichoic acid and lipopolysaccharide of Gram-positive and Gram-negative bacterial membranes, respectively, to destroy the bacterial membrane (PubMed:34506798). In addition, it shows anti-inflammatory effects by inhibiting the expression of pro-inflammatory cytokines that are increased during bacterial infection in Hs27 cells (PubMed:34506798). Expressed by the venom gland. Belongs to the cationic peptide 04 (cupiennin) family. 05 subfamily.