Insecticidal neurotoxin that induces irreversible neuromuscular blockade in house crickets (A.domesticus). Modifies presynaptic voltage-gated sodium channels (Nav), causing them to open at the normal resting potential of the nerve. This leads to spontaneous release of neurotransmitter and repetitive action potentials in motor neurons. Expressed by the venom gland. The presence of a 'disulfide through disulfide knot' structurally defines this protein as a knottin. LD(50) is 20 mg/kg in house crickets (Acheta domesticus). Belongs to the neurotoxin 07 (Beta/delta-agtx) family. 04 (aga-5) subfamily.