Toxic component of a type II toxin-antitoxin (TA) system. An RNase (By similarity). Upon expression in M.smegmatis inhibits colony formation. Its toxic effect is neutralized by coexpression with cognate antitoxin VapB19. Following 6 weeks of nutrient starvation. Up-regulated 2.3-fold 7 days after infection of human macrophages. Belongs to the PINc/VapC protein family.