Myosin is a protein that binds to actin and has ATPase activity that is activated by actin. Together CLIP-190 and jar may coordinate the interaction between the actin and microtubule cytoskeleton. May link endocytic vesicles to microtubules and may be involved in transport in the early embryo and in the dynamic process of dorsal closure. It is believed that its function changes during the life cycle. Microtubule-associated. Additional isoforms seem to exist. Isoform B is present at a higher level in the head and gonads than in the thoraxes. Isoform 145 kDa is found only in the head. CLIP-190 and jar are coexpressed at several times in development and in a number of tissues, including embryonic axonal neuron processes and posterior pole. Isoform B is expressed both maternally and zygotically throughout development with highest level during mid-embryogenesis and adulthood. At these zygotic stages isoform D is also expressed. Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.