Component of the monoterpenoid indole alkaloids (MIAs, e.g. echitovenine, tabersonine, lochnericine, 19-hydroxytabersonine and horhammericine) biosynthetic pathway; MIAs are used in cancer treatment and other medical applications (PubMed:31009114). Cytochrome P450 catalyzing the conversion of tabersonine to lochnericine (PubMed:31009114, PubMed:29934299). (-)-tabersonine + O2 + reduced [NADPH--hemoprotein reductase] = H(+) + H2O + lochnericine + oxidized [NADPH--hemoprotein reductase] Alkaloid biosynthesis. Mainly expressed in aerial organs, including stems, leaves and flowers. Belongs to the cytochrome P450 family.