Catalyzes the hydration of cyclohexyl isocyanide to N-cyclohexylformamide. Acts on various isonitriles, but not on nitriles or amides. Probably involved in detoxification. H(+) + N-cyclohexylformamide = cyclohexyl isocyanide + H2O Sensitive to thiol reagents and oxidizing reagents, but is not influenced by chelators or reducing reagents. Optimum pH is 6.0-6.5. Optimum temperature is 35 degrees Celsius. Activity is rapidly lost above 40 degrees Celsius. Homodimer. Does not require metal ion for activity.