Transcription factor that acts as a cardiac regulator and an effector of alpha1-adrenergic signaling. Binds to PE response elements (PERE) present in the promoter of genes such as ANF/NPPA and acts as a direct transcriptional activator of NPPA. Also acts as a cofactor with GATA4, a key cardiac regulator. Binds DNA. Interacts with GATA4. Expressed in both embryonic, fetal and adult heart. Also expressed in lung, skeletal muscle and adrenal glands. Expressed in cardiomyocytes from E14. Up-regulated by activation of alpha1-adrenergic receptors. Belongs to the krueppel C2H2-type zinc-finger protein family.