Involved in ligand-dependent receptor mediated endocytosis of the EGF and insulin receptors as part of the Ral signaling pathway (By similarity). By controlling growth factor receptors endocytosis may regulate cell survival (By similarity). Through ASAP1 may regulate cell adhesion and migration (By similarity). Interacts with EPN1 (By similarity). Interacts with EPS15 AND EPS15L1 (By similarity). Interacts with RALBP1; can form a ternary complex with activated Ral (RALA or RALB) (By similarity). Interacts with ASAP1; the interaction is direct and this complex can bind paxillin (PubMed:12149250). Also forms a ternary complex with RALBP1 and ASAP1 (By similarity). Interacts with GRB2 (By similarity). Tyrosine-phosphorylated upon stimulation of cells with EGF. Phosphorylation on Tyr-residues induces its association with the EGF receptor probably indirectly through an adapter like GRB2.