PPIases accelerate the folding of proteins. May function in a signal transduction cascade during early development. [protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0) Ubiquitously expressed, highest levels in ovary. Expressed during all stages of development with highest expression in early embryo. Belongs to the FKBP-type PPIase family. It is uncertain whether Met-1 or Met-3 is the initiator.