Helicase; has ATPase activity. Component of the SKI complex which is thought to be involved in exosome-mediated RNA decay and associates with transcriptionally active genes in a manner dependent on PAF1 complex (PAF1C). Component of the SKI complex which consists of WDR61, SKIV2L and TTC37. Interacts with HBS1L isoform 2 (PubMed:28204585). The disease is caused by variants affecting the gene represented in this entry. Belongs to the helicase family. SKI2 subfamily. Truncated N-terminus.