Negatively regulates Golgi-to-plasma membrane trafficking by interacting with PI4KB and inhibiting its activity. May play a role in the physiology of neurons and is potentially important in memory and learning. Interacts with PI4KB. This binding competes with FREQ/NCS1 binding in a calcium-dependent manner. Brain specific. The C-terminal transmembrane domain (TMD) is necessary and sufficient for membrane targeting. Truncated N-terminus.