Carboxylesterase present at high level in urine that regulates production of felinine, a probable pheromone precursor. Probably acts by hydrolyzing the peptide bond of the felinine precursor 3-methylbutanol cyteinylglycine, producing felinine and glycine in cat urine. a carboxylic ester + H2O = a carboxylate + an alcohol + H(+) Present at high level in urine. Expressed in the kidney proximal straight tubular cells and is secreted from the apical compartment of the cells into the urine (at protein level). In mature cats, it is present at higher level in intact males than in castrated males or in intact or spayed females. Present in cats older than about 3 months, and its level increases with age. Strongly down-regulated in cats suffering from tubulointerstitial nephritis (TIN). Excretion decreases immediately after castration. N-glycosylated; contains a fucosylated complex carbohydrate. Protein specifically present in urine of cat. Present at high level in urine of members of the genus Felis and Lynx but not in urine of other felines. Belongs to the type-B carboxylesterase/lipase family.