May only reduce GSH-thiol disulfides, but not protein disulfides (Potential). Probably involved in the regulation of the redox state of the BOLA proteins (Potential). May act as Fe-S cluster donors to Fe-S cluster-requiring proteins (PubMed:18044966). May protect cells against protein oxidative damage (PubMed:16829529). May regulate CAX cation transporters (PubMed:16829529). The GRXS14-BOLA1 heterodimer binds a labile, oxygen sensitive Fe-S cluster (PubMed:24714563). [2Fe-2S]-bridged holo-homodimer (By similarity). Interacts with N-terminal part of CAX1 in yeast (PubMed:12480930). Interacts in vitro with SUFE1, BOLA1, BOLA2 and BOLA4 (PubMed:24203231). Interacts in vivo only with SUFE1, BOLA1 and BOLA4 (PubMed:24203231, PubMed:24714563, PubMed:12480930) (By similarity). Interacts with SBP1 (PubMed:30824043). Highly expressed in leaves, at intermediate levels in stems and at lower levels in roots and flowers. By sodium and magnesium chloride. The C-terminal region (79-168) is involved in BOLA recognition in GRXS-BOLA apo-heterodimer. Plants display high sensitivity to external oxidants, and their content of protein carbonylation is higher than wild-type plants. The GRXS14-BOLA1 apo-heterodimer model derived from NMR data shows a domain arrangement totally different from the holo-heterodimer showing evidence for a Rieske-type ligation of a [2Fe-2S] cluster. Belongs to the glutaredoxin family. CGFS subfamily.