Efflux pump that contributes to intrinsic antibiotic resistance (PubMed:9811639, PubMed:16373429). The pump uses the electrochemical gradient as a source of energy (PubMed:16373429). Confers low-level resistance to tetracycline and to several aminoglycosides, including streptomycin, gentamicin, 2'-N-ethylnetilmicin and 6'-N-ethylnetilmicin (PubMed:9811639, PubMed:16373429). Efflux activity is inhibited by carbonyl cyanide m-chlorophenylhydrazone (CCCP) and reserpine, but not by o-vanadate or chlorpromazine (CPZ). Belongs to the major facilitator superfamily. Drug:H(+) antiporter-3 (DHA3) (TC 2.A.1.21) family.