Part of the tripartite efflux system AcrEF-TolC. Involved in the efflux of indole and organic solvents. Part of the tripartite efflux system AcrEF-TolC, which is composed of an inner membrane transporter, AcrF, a periplasmic membrane fusion protein, AcrE, and an outer membrane component, TolC. The complex forms a large protein conduit and can translocate molecules across both the inner and outer membranes (Probable). Induced by LeuO, part of the acrEF operon. Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.