Antifreeze proteins lower the blood freezing point. Synthesized by the liver and secreted into the blood from which they become distributed to almost the entire extracellular space. Contains 44 copies of AFGP8 and two copies of AFGP7. O-glycosylated; contains disaccharide galactose-N-acetylgalactosamine attached to threonines in AFGP8 and AFGP7. Cool news - Issue 5 of December 2000