Lacks dipeptidase activity and is unable to hydrolyze cystinyl-bis-glycine (PubMed:32325220). The absence of activity may be due to the inability of serine (instead of aspartate found in DPEP1/2) at position 356 to function as the acid/base catalyst and activate the nucleophilic water/hydroxide (PubMed:32325220). Does not hydrolyze leukotriene D4 (LTD4) into leukotriene E4 (LTE4) (PubMed:12738806). Does not hydrolyze the beta-lactam antibiotic imipenem (By similarity). Homodimer; disulfide-linked (By similarity). Interacts with TEX101; co-localized on the cell surface of spermatocytes, spermatids, and testicular spermatozoa, co-localized only in cytoplasmic droplets of caput and corpus epididymal sperm (PubMed:21724266). Expressed in testis but not ovary. Expressed in ovary and testis at 15.5 dpc. No visible phenotype. Mice are fertile despite a significant reduction in sperm count. Belongs to the metallo-dependent hydrolases superfamily. Peptidase M19 family. According to PubMed:12738806, exhibits dipeptidase activity hydrolyzing cystinyl-bis-glycine but according to PubMed:32325220, lacks this activity which may be due to the inability of serine (instead of aspartate found in DPEP1/2) at position 356 to function as the acid/base catalyst and activate the nucleophilic water/hydroxide.