Chemotactic for interleukin-activated T-cells but not unstimulated T-cells, neutrophils or monocytes. Induces calcium release in activated T-cells. Binds to CXCR3. May play an important role in CNS diseases which involve T-cell recruitment. May play a role in skin immune responses (By similarity). Interacts with TNFAIP6 (via Link domain). Belongs to the intercrine alpha (chemokine CxC) family.