Catalyzes hydrolysis of N-hexanoyl-(S)-homoserine lactone, but not the R-enantiomer. Hydrolyzes short- and long-chain N-acyl homoserine lactones with or without 3-oxo substitution at C3, has maximum activity on C10-AHL. an N-acyl-L-homoserine lactone + H2O = an N-acyl-L-homoserine + H(+) Binds 2 Zn(2+) ions per subunit. Monomer. Belongs to the metallo-beta-lactamase superfamily.