Antimicrobial peptide that acts against Gram-positive bacteria but not against Gram-negative bacteria (PubMed:23093408). It selectively inhibits peptidoglycan biosynthesis through complex formation with the cell wall precursor lipid II (1:1 molar ratio) thus inhibiting cell wall synthesis (PubMed:23093408). It does not disrupt cell membranes (PubMed:23093408). In vivo, is effective against an intraperitoneal infection with S.pneumoniae (PubMed:23093408). In vitro, it shows very low hemolytic and cytolytic activities (PubMed:23093408). Has the lowest denaturation temperature of 56.5 degrees Celsius at pH 7. Binding to DPC micelles does not affect the thermal stability in alpkaline pH. Has the lowest denaturation temperature of 71.7 degrees Celsius at pH 2. Binding to DPC micelles strongly increases the thermal stability in acidic pH. The Cys-4-Pro-5 bond is in cis conformation, whereas Gly-29-Pro-30 and His-35-Pro-36 bonds are in trans conformations. Belongs to the invertebrate defensin family.