May play a role in axon growth and regeneration. May be involved in epidermal cell adhesion and epidermal structure and function. Heterooligomeric complex of flotillins 1 and 2. In neuronal cells, associated with GPI-anchored cell-adhesion molecules. Normally expressed in growing retinal exons of newly differentiated ganglion cells at the retinal margin. After optic nerve injury, expressed in all retinal ganglion cells and retinal axons. Also expressed in endothelial cells, spinal cord, larval and adult skin, muscle processes, thymus and gill macrophages. By optic nerve injury. Palmitoylation may be required for the formation of higher order complexes and for neurite outgrowth in cultured neural stem cells. Belongs to the band 7/mec-2 family. Flotillin subfamily.