Has hemolytic and lethal activities. Its hemolytic activity is inhibited by anionic lipids, especially potently by cardiolipin. Heterodimer of alpha and beta subunits. Secreted into the venom gland lumen. The secretion is proved by the fact that the complete sequence showed below is found in the venom gland's lumen, although no signal peptide has been found. This protein may follow a novel secretion pathway. It has been reported that venom-secreting cells of stonefishes do not possess Golgi apparatus and rough endoplasmic reticulum. Expressed by the venom gland. Not glycosylated. Four intrachain disulfide linkages are present in the heterodimer. No interchain disulfide bound links the two subunits. LD(50) is 0.047 mg/kg by intravenous injection into mice. Belongs to the SNTX/VTX toxin family.