Catalyzes the cis-trans isomerization of peptidyl prolyl bonds and accelerates protein folding. Also exhibits chaperone-like activity. [protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0) Contains an N-terminal PPIase domain and an IF (Insert in the Flap) domain. Belongs to the FKBP-type PPIase family.