ATP-binding RNA helicase involved in the biogenesis of 60S ribosomal subunits and is required for the normal formation of 25S and 5.8S rRNAs. Required for the maintenance of dsRNA killer plasmid. ATP + H2O = ADP + H(+) + phosphate The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis. Present with 981 molecules/cell in log phase SD medium. Belongs to the DEAD box helicase family. DDX24/MAK5 subfamily.