Has kallikrein-like activity, releases bradykinin from kininogen. Catalyzes the hydrolysis of various arginine ester substrates for trypsin and thrombin and degrades both angiotensin I and II by cleavage of the dipeptide Asp-Arg from the NH2-terminal end. Fibrinogen is also degraded but a fibrin clot is not produced. May have a potentiating effect on potent hemorrhagic toxins present in the venom. Expressed by the mandibular venom gland. Extensively glycosylated, contains approximately 8 mol of monosaccharide per mol of toxin. LD(50) is 2.5 mg/kg of body weight by intravenous injection into mice. Belongs to the peptidase S1 family. There is a significant difference between sequences of PubMed:20631207 and PubMed:8408054. The sequence of PubMed:8408054 may contain multiple errors since its last cysteine is absent from all other lizard toxin sequences and an insertion of 6 amino acids is present that is missing in other varanid lizard kallikrein toxins.