Shows strong localization in the vicinity of the cell membrane. Shows perinuclear localization. Additional isoforms seem to exist. Isoform 1 and isoform 3 are expressed in brain, heart, kidney, liver, lung, pancreas and placenta but are not detected in skeletal muscle. The disease is caused by variants affecting the gene represented in this entry. Belongs to the TMEM260 family. Truncated N-terminus.