Catalyzes the hydrolysis of bioactive endogenous fatty acid amides to their corresponding acids (PubMed:16624618). The hydrolysis of endogenous amidated lipids terminates their participation as lipid mediators in various signaling systems (Probable). Converts a wide range of N-acylethanolamines (NAEs) to their corresponding free fatty acids and ethanolamine (PubMed:16624618). H2O + N-(9Z,12Z-octadecadienoyl)-ethanolamine = (9Z,12Z)-octadecadienoate + ethanolamine H2O + N-hexadecanoylethanolamine = ethanolamine + hexadecanoate H2O + N-dodecanoylethanolamine = dodecanoate + ethanolamine Inhibited by methyl arachidonyl fluorophosphonate (MAFP). Forms homodimers. Belongs to the amidase family. Truncated N-terminus. Truncated N-terminus. Truncated N-terminus.