Induces relaxation of rat smooth muscle from tail artery (EC(50)=16.8 nM) and contraction of that from ileum (EC(50)=205 nM), urinary bladder (EC(50)=895 nM) and uterus (EC(50)=60.3 nM). Binds to both bradykinin receptor B1 (BDKRB1) and B2 (BDKRB2). [Hyp3,Thr6]-bradykinin: Induces relaxation of rat smooth muscle from tail artery (EC(50)=56.7 nM) and contraction of that from ileum (EC(50)=588 nM), urinary bladder (EC(50)=4.6 uM) and uterus (EC(50)=3.9 nM). Binds to both bradykinin receptor B1 (BDKRB1) and B2 (BDKRB2). In arterial smooth muscle, the effect via BDKRB1 is stronger, in uterus, ileum and urinary bladder the effect via BDKRB2. Induces relaxation of rat smooth muscle from tail artery (EC(50)=10.8 nM) and contraction of that from ileum (EC(50)=645 nM), urinary bladder (EC(50)=1.1 uM) and uterus (EC(50)=1.2 uM). Binds to both bradykinin receptor B1 (BDKRB1) and B2 (BDKRB2). Apart from uterus smooth muscle, the effect via BDKRB2 is stronger. [Hyp3,Thr6]-bradykinyl-Val,Asp: Induces relaxation of rat smooth muscle from tail artery (EC(50)=3.5 nM) and contraction of that from ileum (EC(50)=223 nM), urinary bladder (EC(50)=1.5 uM) and uterus (EC(50)=356 nM). Binds to both bradykinin receptor B1 (BDKRB1) and B2 (BDKRB2); the effects via BDKRB2 are stronger. Expressed by the skin glands. [Hyp3,Thr6]-bradykinyl-Val,Asp. [Thr6]-bradykinyl-Val,Asp. [Hyp3,Thr6]-bradykinin. [Thr6]-bradykinin. Belongs to the frog skin active peptide (FSAP) family. Bradykinin-related peptide subfamily.