May play a critical role in development of the progeny of eagle-positive neuroblasts. During embryonic stages 10 and 11, expression was observed in four neuroblasts, NB2-4, NB3-3, NB6-4 and NB7-3. Except for NB6-4, expression reaches a maximum at the very beginning of expression or in the period of neuroblast delamination. Weak expression is also observed in a few putative progeny of NB7-3 during late embryonic stage 11 and 12. All eagle expression in abdominal segments disappears by stage 13. EG cells fail to acquire the neural fate or underwent an extremely delayed differentiation, while EW neurons produced neurites in abnormal directions. Belongs to the nuclear hormone receptor family. NR0 subfamily.