Transports S-adenosylmethionine (SAM) and S-adenosylhomocysteine (SAH). Allows bacteria to acquire SAM from the eukaryotic host cell and to likely remove the toxic by-product SAH. CCCP treatment reduces SAM intracellular uptake by 50%. Belongs to the drug/metabolite transporter (DMT) superfamily. 10 TMS drug/metabolite exporter (DME) (TC 2.A.7.3) family.