Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit. The complex from the organism is particularly stable to disruption and remains functional after 6 hrs at 55 degrees Celsius. ATP + 4 H(+)(in) + H2O = ADP + 5 H(+)(out) + phosphate Inhibited by dicyclohexylcarbodiimide. Optimum temperature is 55 degrees Celsius, activity was detected from 4 to 95 degrees Celsius. F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has four main subunits: a(1), b(1), b'(1) and c(9-12). Belongs to the ATPase alpha/beta chains family.