Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane. Plays a role in export of a number of proteins from the cell including glycosylated PsrP and pneumolysin (ply) (PubMed:28456649). ATP + H2O + cellular proteinSide 1 = ADP + phosphate + cellular proteinSide 2. Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved. Distribution is 50-50. A single gene deletion has about 60% decreased biofilm formation, 75% decreased adherence to human lung pneumocytes. Has higher pneumolysin (ply) i.e. hemolytic activity in the cytoplasm but less in the cell wall. Decreased levels of a number of cell wall and secreted proteins (PubMed:28456649). Deletion of 15 genes (from psrP, SP_1772 to SP_1756, includes the accessory Sec export proteins SecA2 and SecY2) and infection of female BALB/cJ mice, shows the psrP-secY2A2 region is required for lung infection and for infection to progress to blood. Mice infected intraperitoneally showed wild-type infection. Decreased adherence to lung but not pharynx or brain cells. The psrP-secY2A2 region deletion has no effect on bacterial growth rate, capsule levels, autolysis, or transformation (PubMed:18507531). In vitro significantly decreased biofilm formation is seen; the large deletion mutant (SP_1772 to SP_1756) is no more affected than the single psrP deletion (PubMed:20714350). Encoded in RD10, a pathogenicity island with an atypical GC content that is associated with invasive pneumococcal disease. Pathogenicity islands account for greater than half the genomic diversity observed between isolates (PubMed:11463916, PubMed:16861665). The main function of this island seems to be correct synthesis and export of pneumococcal serine-rich repeat protein PsrP (PubMed:18507531, PubMed:20714350). Belongs to the SecA family.