Participates in the regulation of cellular Ca(2+) homeostasis, at least partly, by modulating the filling state of the endoplasmic reticulum Ca(2+) store (By similarity). In neurons and glial cells, has a role in maintaining neuronal function and integrity during aging (PubMed:29357349). Detected in adult brain. RNAi-mediated knockdown in neurons results in age-dependent behavioral deficits and neurodegeneration, which is further enhanced when the knockdown is in both neurons and glial cells; the defects include age-dependent locomotor deficits, increased susceptibility to oxidative stress and glutamate excitotoxicity, increased age-dependent appearance of vacuoles in the central neuropil and optic lobes of the fly brain, and shortened lifespan. Truncated C-terminus.