Involved in regulating cell motility and cell-matrix interactions. May inhibit cell growth through suppression of cell proliferation (By similarity). Homodimer. Dimer formation occurs predominantly through cis interactions on the cell surface (By similarity). Part of a complex containing MLC1, TRPV4, AQP4 and ATP1B1 (By similarity). Colocalizes with CDH1. The cytoplasmic domain plays an important role in regulation of cell-matrix adhesion and cell motility. N-glycosylated.