Hydrolase that specifically degrades the potent antimicrobial compound 2,4-diacetylphloroglucinol (DAPG) to equimolar amounts of mildly toxic monoacetylphloroglucinol (MAPG) and acetate. 2,4-diacetylphloroglucinol + H2O = 2-acetylphloroglucinol + acetate kcat is 4.7 sec(-1). Homodimer. Contains a small N-terminal domain involved in dimerization and a large C-terminal Bet v1-like fold catalytic domain. Belongs to the DAPG/phloretin hydrolase family.