Regulates cell growth, chemotaxis, signal relay and the actin cytoskeleton. Functions as a part of 2 distinct protein complexes TORC1 and TORC2. TORC1 is a rapamycin-sensitive complex that controls cell growth in response to nutrients and growth factors. The second TOR complex, TORC2, is presumed to be indirectly negatively modulated by rapamycin and regulates actin polarization. TORC2 but not TORC1 negatively regulates phagocytosis. TORC2-dependent regulation of the cytoskeleton may follow differential phosphorylation of pkbA. May have some protein kinase activity, as it appears to phosphorylate pkgB. ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein] ATP + L-threonyl-[protein] = ADP + H(+) + O-phospho-L-threonyl-[protein] Part of a complex, TORC1, consisting of tor, raptor and lst8. Part of a complex, TORC2, consisting of tor, lst8, piaA and ripA. Additional proteins, such as 14-3-3 and heat-shock proteins, may also belong to the TORC2 complex. Null cells are lethal due to a growth defect involving TOR protein complex 1, TORC1. Belongs to the PI3/PI4-kinase family.