May play a role in subcellular trafficking between the endoplasmic reticulum and Golgi apparatus through interactions with the Rho-type GTPases. Homodimer. Binds to MLF1, recruiting a serine kinase which phosphorylates both itself and MLF1. Phosphorylated MLF1 binds to YWHAZ and is retained in the cytoplasm (By similarity). Colocalizes with activated RAC3 to endomembranes and at the cell periphery in lamellipodia. The protein kinase domain is predicted to be catalytically inactive. Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.