Plays an essential role in the survival of diffuse-type gastric cancer cells. Acts as a nucleolar anchoring protein for DDX47. May be involved in regulation of gene expression at the post-transcriptional level or in ribosome biogenesis in cancer cells. Interacts with the GTP form of RRAGA, RRAGC and RRAGD. Interacts with NIP7. Interacts with DDX18; the interaction is RNA-dependent. Interacts with DDX47; the interaction is RNA-dependent. Localizes in the nucleolar-organizing region during ribosome biogenesis. Expressed in various diffuse-type gastric cancers. Detected at lower levels in skeletal muscle. Up-regulated in diffuse-type gastric cancers. Phosphorylated. Truncated N-terminus. Truncated N-terminus. Truncated N-terminus.