Component of the EvC complex that positively regulates ciliary Hedgehog (Hh) signaling (PubMed:21356043, PubMed:24582806). Plays a critical role in bone formation and skeletal development (PubMed:21356043). May be involved in early embryonic morphogenesis (PubMed:21356043). Component of the EvC complex composed of EFCAB7, IQCE, EVC2 and EVC; built from two subcomplexes, EVC2:EVC and EFCAB7:IQCE (PubMed:24582806). Interacts with EVC (PubMed:21356043, PubMed:24582806). Interacts (via N-terminal end) with EFCAB7 (PubMed:24582806). Interacts (via N-terminal end) with IQCE (PubMed:24582806). The EvC complex localizes at the base of cilia in the EvC zone of primary cilia in a EFCAB7-dependent manner (PubMed:24582806). Expressed in long and cranial bones, kidney and heart. Strongly expressed in proliferating chondrocytes, osteoblasts and osteoclasts. Found in the embryo at day 7 dpc, 11 dpc, 15 dpc, and 17 dpc. At the limb bud formation stage 11 dpc, it is expressed in fore- and hindlimb buds, branchial arches, and facial primordia.