Shows trans-enoyl-CoA hydratase/3-hydroxyacyl-CoA dehydratase activity. In vitro, can hydrate (2E)-butenoyl-CoA, (2E)-hexenoyl-CoA and (2E)-decenoyl-CoA. a (3R)-3-hydroxyacyl-CoA = a (2E)-enoyl-CoA + H2O (3R)-3-hydroxybutanoyl-CoA = (2E)-butenoyl-CoA + H2O (3R)-hydroxyhexanoyl-CoA = (2E)-hexenoyl-CoA + H2O (3R)-3-hydroxydecanoyl-CoA = (2E)-decenoyl-CoA + H2O kcat is 110 sec(-1) with butenoyl-CoA as substrate. Homodimer. Belongs to the enoyl-CoA hydratase/isomerase family.