Component of the elongator complex which is required for multiple tRNA modifications, including mcm5U (5-methoxycarbonylmethyl uridine), mcm5s2U (5-methoxycarbonylmethyl-2-thiouridine), and ncm5U (5-carbamoylmethyl uridine) (By similarity). The elongator complex catalyzes formation of carboxymethyluridine in the wobble base at position 34 in tRNAs (By similarity). Promotes organ development by modulating cell division rate. Involved in oxidative stress signaling. Prevents anthocyanins accumulation (PubMed:19500300). tRNA modification; 5-methoxycarbonylmethyl-2-thiouridine-tRNA biosynthesis. Component of the elongator complex which consists of ELP1/ELO2, ELP2, ELP3/ELO3, ELP4/ELO1, ELP5, and ELP6. Interacts directly with ELP4. Expressed in leaves, stems, roots, flowers, siliques and guard cells. Narrow leaves and reduced root growth that results from a decreased cell division rate. Higher resistance to oxidative stress mediated by methyl viologen (MV) that blocks electron transport during photosynthesis and by CsCl in light. Accumulates anthocyanins. Belongs to the ELP6 family. The elongator complex was originally thought to play a role in transcription elongation. However, it is no longer thought to play a direct role in this process and its primary function is thought to be in tRNA modification.