Required for glucose-induced micropexophagy and ethanol-induced macropexophagy (PubMed:15563611). Involved in the fusion between the pexophagosome and the vacuole. Also involved in the separation or division of vacuoles throughout the entire life cycle of the cells (PubMed:15563611). Vacuolar and other perivacuolar punctate structures. The PX domain binds phosphatidylinositol 3-phosphate which is necessary for peripheral membrane localization to the perivacuolar punctate structures. Belongs to the sorting nexin family.