Functions as a positive effector of the Wnt signaling pathway regulating antero-posterior neural patterning. Homomers. Interacts with dishevelled and axin1. Expressed throughout the embryo including the shield. Strongly expressed in notochord and head regions from the bud to somite stages. Expressed in early born neurons in the telencephalic nucleus, the nuclei of the tract of the post-optic commissure and of the medial longitudinal fasciculus, and in segmental clusters of neurons in the hindbrain. The DIX domain mediates self-interaction and interaction with dishevelled and axin1. Belongs to the DIXDC1 family.