DNA-binding helicase that specifically binds to the promoter of target genes, leading to chromatin remodeling, possibly by promoting deposition of histone H3.3. Involved in myogenesis via interaction with MYOD1: binds to myogenic gene regulatory sequences and mediates incorporation of histone H3.3 prior to the onset of myogenic gene expression, promoting their expression (By similarity). ATP + H2O = ADP + H(+) + phosphate Interacts with MYOD1. Interacts with histone H3.3 (By similarity). Binds to myogenic gene promoters. The disease is caused by variants affecting the gene represented in this entry. Belongs to the SNF2/RAD54 helicase family.