Plays a role in lysosomes motility (PubMed:30174114). In neurons, mediates the anterograde axonal long-range transport of presynaptic lysosome-related vesicles required for presynaptic biogenesis and synaptic function (PubMed:30174114). May play a role in chromosome segregation (By similarity). Interacts with PLEKHM1. Localizes with microtubules at the spindle mid-zone during mitosis. Belongs to the small GTPase superfamily. Arf family.