May play a role in DNA-protein cross-links (DPCs) clearance through a SUMO-dependent recruitment to sites of DPCs, ensuring the genomic stability by protecting germ cells and early embryos from various sources of damage (PubMed:30914427, PubMed:31839537, PubMed:31839538). May resolve the topoisomerase II (top-2) DPCs (PubMed:31839537, PubMed:31839538). Limits replication stress and DNA double-strand breaks (PubMed:31839537). Interacts with top-2; this interaction allows the resolution of topoisomerase II (top-2) DNA-protein cross-links. Localizes on condensed chromosomes in spermatocytes in G2 and M during meiotic prophase (PubMed:31839538). Colocalizes with top-2 on condensed chromosomes during embryonic cell divisions (PubMed:31839538). Mainly expressed in germ cells and early embryonic, proliferating cells. Mutant worms become hypersensitive to formaldehyde-induced DNA damage (PubMed:30914427). Mutant worms exhibit significant reduction in brood size at 25 degrees Celsius and also exhibit a high incidence of male progeny at both 20 and 25 degrees Celsius (PubMed:27718356, PubMed:31839537). Moreover, exhibit a mortal germline (MRT) phenotype characterized by transgenerational loss of fecundity and vitality, marked by reduced lifespan, decreased mobility, and loss of fertility in later generations (PubMed:31839537). Mutants have a mortal germline, where brood sizes become progressively smaller and the population fails to survive beyond 12 generations (PubMed:31839538). Belongs to the serine-aspartate repeat-containing protein (SDr) family.