Forms a complex composed of PDGFRL, TNK2 and GRB2. Expressed in colon, lung and liver. The gene represented in this entry is involved in disease pathogenesis. A polymorphism in PDGFRL has been reported to be associated with susceptibility to Behcet disease (PubMed:22926996). Behcet disease is a complex multiple-system disorder characterized by recurrent oral ulcerations, recurrent genital ulcerations, typical skin lesions, and uveitis. Behcet disease also involves joints, blood vessels, musculoskeletal, neurological systems, and the gastrointestinal tract.