Poor inhibitor of platelet aggregation. The disintegrin inhibits the adhesion of the alpha-4/beta-1 (ITGA4/ITGB1) integrin to VCAM-1. Inhibition on alpha-IIb/beta-3 (ITGA2B/ITGB3) is low. Heterodimer with EO5B; disulfide-linked. Expressed by the venom gland. Does not show inhibition of inhibition on alpha-1/beta-1 (ITGA1/ITGB1), alpha-2/beta-1 (ITGA2/ITGB1) and alpha-6/beta-1 (ITGA6/ITGB1). Belongs to the disintegrin family. Dimeric disintegrin subfamily.