This is a membrane-bound, calmodulin-sensitive adenylyl cyclase. Inactivation of this cyclase leads to a learning and memory defect. ATP = 3',5'-cyclic AMP + diphosphate Binds 2 magnesium ions per subunit. Activated by calcium/calmodulin and G protein. Mushroom bodies of the fly brain. Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.