Involved in calcium binding and uptake in yeast phase. Required for growth in limiting calcium conditions and for yeast survival in host macrophages. Is able to bind a variety of lipids. Binds 1 Ca(2+) ion per monomer. Thermostable up to 53 degrees Celsius. Homodimer. Expressed in the yeast phase during infection, and not in mycelia. Most abundant protein released by H.capsulatum. Its production continues as the yeast multiplies inside host cells. May be glycosylated.