Calcium/calmodulin-regulated and magnesium-dependent enzyme that catalyzes the hydrolysis of ATP coupled with the transport of calcium out of the cell (By similarity). By regulating sperm cell calcium homeostasis, may play a role in sperm motility (By similarity). ATP + Ca(2+)(in) + H2O = ADP + Ca(2+)(out) + H(+) + phosphate Activated by calcium/calmodulin. Interacts with PDZD11. Interacts with SLC35G1 and STIM1. Interacts with calmodulin. There is a combination of two alternatively spliced domains at N-terminal site A (X and Z) and at C-terminal site C (A and B). Ubiquitously expressed. Not detected in liver. The highest levels are found in uterus and stomach. Isoform XA is found in uterus, brain, stomach, small intestine, colon and pancreas. Isoform XB is found in uterus, skeletal muscle, lung, kidney, spleen, stomach, small intestine and pancreas. Isoform ZA is found in testis and isoform ZB is found in testis and heart. Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIB subfamily.