Phosphatase which catalyzes the conversion of NADP(+) to NAD(+) and of NADPH to NADH (PubMed:31147539). Shows a small preference for NADPH over NADP(+) (PubMed:31147539). Because of its association with the CCR4-NOT complex, has a role in mRNA deadenylation and decay (PubMed:20504953). Required at the pupal stage for proper wing morphogenesis after eclosion (PubMed:19581445). Doesn't have a role in light-mediated behavioral response. In dorsal neurons, contributes to the light-mediated behavioral response. Doesn't have a role in light-mediated behavioral response. H2O + NADP(+) = NAD(+) + phosphate H2O + NADPH = NADH + phosphate Binds 2 magnesium ions, but the ions are only loosely bound to the protein. Associates to the CCR4-NOT complex composed of at least Pop2/Caf1-55, Ccr4, Not1, Rga/Not2, and Not3. Expressed in the head, in the dorsal neurons DN3, a subgroup of clock neurons (at protein level) (PubMed:19966839). Ubiquitously expressed in both males and females (PubMed:19581445). Expressed at every stage (PubMed:19581445). Expressed in the embryonic salivary glands, the distal part of the proventriculus and the ring gland as well as weak expression in the midgut (PubMed:19581445). At third instar larval stage, expressed at the proventricular and ring gland (PubMed:19581445). No transcript detected in the larval central brain, in the imaginal disks, the salivary glands, or in the fat body (PubMed:19581445). Nutritional conditions, such as food deprivation, and higher temperature during the larval stage increase protein expression in the adult flies (Ref.7, PubMed:19581445). Levels of expression at the pupal stage are phenocritical for the cu-dependent wing phenotype (PubMed:19581445). In the dorsal neurons DN3, a subgroup of clock neurons, accumulates rhythmically with a peak around ZT12 (PubMed:19966839). Viable and fertile with upward bent (curled) wings and proximally crossed posterior scutellar bristles (PubMed:19581445). RNAi-mediated knockdown has a similar phenotype (PubMed:19581445). RNAi-mediated knockdown in the wing, nervous system, ring gland, muscles, fat body, tracheal system, salivary gland, or gut has no impact on wing morphogenesis (PubMed:19581445). Belongs to the CCR4/nocturin family. The purified protein lacks deadenylase activity.