May be involved in several stages of intracellular trafficking. Overexpression of SNX15 disrupts the normal trafficking of proteins from the plasma membrane to recycling endosomes or the TGN. Homodimer. Interacts with SNX1, SNX2 and SNX4. Widely expressed. The PX domain mediates interaction with membranes enriched in phosphatidylinositol 3-phosphate. Belongs to the sorting nexin family.