Catalyzes CTP-mediated phosphorylation of dolichol, the terminal step in de novo dolichyl monophosphate (Dol-P) biosynthesis (PubMed:12213788, PubMed:16923818, PubMed:17273964). Dol-P is a lipid carrier essential for the synthesis of N-linked and O-linked oligosaccharides and for GPI anchors (PubMed:12213788). CTP + di-trans,poly-cis-dolichol = a dolichyl phosphate + CDP + H(+) Ubiquitous. The disease is caused by variants affecting the gene represented in this entry. Complements the defects in growth, dolichol kinase activity and protein N-glycosylation at the restrictive temperature in yeast sec59 mutant cells. Belongs to the polyprenol kinase family.