Plays a role in the regulation of lifespan in a partially daf-16-mediated manner, and may be involved in regulating the levels of reactive oxygen species production in response to heat stress. RNAi-mediated knockdown in young adults results in an increased adult lifespan. At 37 degrees Celsius, levels of reactive oxygen species are reduced compared to wild-type animals. Double knockout with atad-3 RNAi results in an enhanced increase in adult lifespan as compared to the single mutants and wild-type animals. Has been shown to interact (via PDZ domain) with atad-3 (via C-terminus) (PubMed:22245785). The physiological significance of this interaction is uncertain; the atad-3 C-terminus is expected to be within the mitochondrial matrix.