Probable endo-1,3(4)-beta-glucanase involved in the cell separation process. Endohydrolysis of (1->3)- or (1->4)-linkages in beta-D-glucans when the glucose residue whose reducing group is involved in the linkage to be hydrolyzed is itself substituted at C-3. Expression is down-regulated in presence of human keratinocytes. Belongs to the glycosyl hydrolase 81 family.