Cytokine which is the ligand for CD27. The CD70-CD27 pathway plays an important role in the generation and maintenance of T cell immunity, in particular during antiviral responses. Upon CD27 binding, induces the proliferation of costimulated T-cells and enhances the generation of cytolytic T-cells. Homotrimer. Very low level of expression. Detected in splenocytes and thymocytes. By IL-2 and concanavalin A (Con A). N-glycosylated. Belongs to the tumor necrosis factor family.