Plays a role in endosomal trafficking of the epidermal growth factor receptor (EGFR). Interacts with EGFR. Expressed in stomach, lung and skin (at protein level). In stomach, strongly expressed in the mucosa of the fundus, in epithelial cells of gastric pits, and in gastric glands (at protein level). In skin, expressed in the epidermis, dermis, and epithelial layer of the hair bulb (at protein level). Detected in stomach and skin from embryonic stage 16 (16 dpc) onwards. Belongs to the syntaxin family.