Integrin alpha-10/beta-1 is a receptor for collagen. Heterodimer of an alpha and a beta subunit. Alpha-10 associates with beta-1. Widely expressed with highest expression in muscle and heart. Found in articular cartilage. The integrin I-domain (insert) is a VWFA domain. Integrins with I-domains do not undergo protease cleavage. Belongs to the integrin alpha chain family.