Involved in the activation and maintenance of cell division in the meristems and by this controls cell numbers in differentiated organs. Its action in cell cycle regulation may be directed through the RB-E2F pathway. Ubiquitously expressed. The NET domain could serve as an interface to localize different proteins or complexes to chromatin. Cell numbers are significantly reduced in most of the organs. Cell cycle reactivation is delayed in germinating seeds, and a premature switch from mitosis to endoreduplication occurs. Furthermore, a partial loss of root quiescent center (QC) identity is observed.