May regulate lymphocyte survival. Required for normal levels of mature T-lymphocytes and mature B-cells. Expressed in thymus, spleen (in splenocytes), lymph node and lung (PubMed:16509771, PubMed:20194894). Detected in mature B-cells and thymocytes (at protein level) (PubMed:20194894). Severe lymphophenia, leading to death soon after birth. Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family. IAN subfamily. Wrong choice of frame. Wrong choice of frame.