ATP + H2O = ADP + H(+) + phosphate Expressed in lymphoid tissues (at protein level). Expressed in brain, heart, skeletal muscle, colon, thymus, spleen, kidney, liver, small intestine, placenta, lung, lymphoid tissues and blood leukocytes. Up-regulated by ionomycin in T-lymphocytes. Down-regulated in acute lymphoblastic leukemia. Belongs to the DEAD box helicase family. DEAH subfamily.