CBASS (cyclic oligonucleotide-based antiphage signaling system) provides immunity against bacteriophage. The CD-NTase protein synthesizes cyclic nucleotides in response to infection; these serve as specific second messenger signals. The signals activate a diverse range of effectors, leading to bacterial cell death and thus abortive phage infection. A type II-A(GA) CBASS system (PubMed:32839535). Phospholipase that is activated upon binding to the cyclic dinucleotide (CDN) second messenger 3',3'-cyclic GMP-AMP (3',3'-cGAMP) (PubMed:29891656, PubMed:30787435). Thus, degrades phosphatidylethanolamine (PE) and phosphatidylglycerol (PG), the major phospholipids in the cell membrane of V.cholerae, releasing 16:1 and 18:1 free fatty acids (PubMed:29891656). Protects E.coli against phage P1 and T2 infection. When the 4 gene operon capV-dncV-cap2-cap3 is introduced in E.coli MG1655 there is about 100-fold protection against phages P1 and T2 (PubMed:31533127). Protects E.coli against phage T2 infection. When the CBASS operon (capV-dcnV-cap2-cap3) is introduced in E.coli MG1655 there is a more than 10(3) decrease in the efficiency of T2 plaque formation. Protects 100-fold against phage T5, offers no protection against T7 (PubMed:32544385). a 1,2-diacyl-sn-glycero-3-phosphocholine + H2O = a 2-acyl-sn-glycero-3-phosphocholine + a fatty acid + H(+) 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine + 2 H2O = 2 (9Z)-octadecenoate + 2 H(+) + sn-glycero-3-phosphoethanolamine Phospholipase activity is specifically activated upon 3',3'-cGAMP binding. Is not activated by the other cyclic dinucleotides 3',3'-cUAMP, 3',3'-c-diAMP and 3',3'-c-diGMP. Therefore, is specifically activated by only the nucleotide synthesized from its adjacently encoded nucleotidyltransferase (DncV). Part of the CBASS operon consisting of capV-dncV-cap2-cap3. Deletion of capV suppresses cGAMP-dependent growth phenotypes resulting from overexpression of dncV. Belongs to the patatin family.