Glutathione S-transferase that catalyzes the conjugation of glutathione to exogenous and endogenous compounds (PubMed:14709161, PubMed:14742434). Significant glutathione conjugating activity is found only with the model substrate, 1-chloro-2,4-dinitrobenzene (CDNB) (PubMed:14709161). glutathione + RX = a halide anion + an S-substituted glutathione + H(+) Homodimer. Ubiquitous. Belongs to the GST superfamily. Kappa family.