Pseudokinase that plays a role in viral DNA replication repression by activating the antiviral protein BANF1 and inhibiting the activity of host VRK1, a cellular modulator of BANF1. Both catalytically active kinases B1/VPK1 and host VRK2 repress B12 inhibitory activity in a B1/VPK1 deletion mutant strain. Interacts with B1/VPK1. Interacts with host VRK1. Interacts with host VRK2. Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. Poxviruses subfamily.