Effector proteins function to alter host cell physiology and promote bacterial survival in host tissues. This protein is an E3 ubiquitin ligase that interferes with host's ubiquitination pathway (By similarity). Secreted via type III secretion system (TTSS), and delivered into the host cytoplasm. The LRR (leucine-rich repeat) domain forms a slightly curved solenoid and may mediate interaction with target proteins. Ubiquitinated in the presence of host E1 ubiquitin-activating enzyme, E2 ubiquitin-conjugating enzyme and ubiquitin. Belongs to the LRR-containing bacterial E3 ligase family.