Required for normal progression through mitosis. Required for normal congress of chromosomes at the metaphase plate, and for normal rate of chromosomal segregation during anaphase. Plays a role in the regulation of mitotic spindle dynamics. Increases the rate of turnover of microtubules on metaphase spindles, and contributes to the generation of normal tension across sister kinetochores. Recruits KIF2A and ANKRD53 to the mitotic spindle and spindle poles. May participate in p53/TP53-regulated growth suppression (By similarity). Interacts with APC2 (PubMed:17310996). Interacts with KIF2A (By similarity). Interacts with ANKRD53; recruits ANKRD53 to the spindle during mitosis (By similarity). Detected at the mitotic spindle and spindle poles. Diffusely distributed throughout the cell during interphase (By similarity). Highly expressed in heart, brain and lung. Weaker expression in kidney and testis. Induced by adriamycin and mitomycin C, in a p53-dependent manner, in NIH3T3 cells. This induction is inhibited by actinomycin D. Also induced by cisplatin in a p73-dependent manner in embryonic cells. Phosphorylated during mitosis. Belongs to the PSRC1 family.