Sodium-dependent and purine-selective transporter (PubMed:9435697, PubMed:10087507). Exhibits the transport characteristics of the nucleoside transport system cif or N1 subtype (N1/cif) (selective for purine nucleosides and uridine) (PubMed:9435697, PubMed:10087507). Plays a critical role in specific uptake and salvage of purine nucleosides in kidney and other tissues (PubMed:9435697). adenosine(out) + Na(+)(out) = adenosine(in) + Na(+)(in) inosine(out) + Na(+)(out) = inosine(in) + Na(+)(in) guanosine(out) + Na(+)(out) = guanosine(in) + Na(+)(in) Na(+)(out) + uridine(out) = Na(+)(in) + uridine(in) Inhibited by formycin B. Expressed in heart and skeletal muscle followed by liver, kidney, intestine, pancreas, placenta and brain (PubMed:9435697). Weak expression in lung (PubMed:9435697). Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family.