Monomer. Expressed in saliva (at protein level) (PubMed:23464525). Expressed in dander (at protein level) (PubMed:22515174, PubMed:23464525). According to PubMed:22104604, expressed in submaxillary gland (PubMed:22104604). In contrast, according to PubMed:22515174, not expressed in submaxillary gland. Expressed in bladder and skin, but not in tongue (PubMed:22515174). Causes an allergic reaction in human. Binds to IgE (PubMed:22104604, PubMed:22515174, PubMed:23464525, PubMed:23464491, PubMed:29207604, PubMed:30728436). Binds to IgE in 61% of the 44 patients tested allergic to both dog and cat dander (PubMed:22104604). Binds to IgE in 38% of the 100 patients tested allergic to dog dander (PubMed:22515174). Binds to IgE in all 3 patients tested allergic to both dog and horse dander (PubMed:23464491). Binds to IgE in 56% of the 32 Chinese children tested allergic to dog (PubMed:29207604). Binds to IgE in 47% of the 38 patients tested allergic to dog dander (PubMed:30728436). Causes activation of human basophils (PubMed:22515174, PubMed:29207604). Belongs to the calycin superfamily. Lipocalin family.