Immunoglobulin-like receptor which plays an inhibitory role in degranulation of mast cells. Negatively regulates IgE-mediated mast cell activation and suppresses the type I immediate hypersensitivity reaction. Monomer (Probable). Interacts (tyrosine-phosphorylated) with PTPN6, PTPN11 and INPP5D. Expressed in myeloid cells (dendritic cells, macrophages and neutrophils but not in T-cells, B-cells or natural killer cells) and mast cells (at protein level). N-glycosylated. Enhanced IgE-mediated, mast cell-dependent passive systemic anaphylaxis. No effect on differentiation of hematopoietic cells, including mast cells. Truncated N-terminus.