Component of the replication protein A complex (RPA) required for DNA recombination, repair and replication. The activity of RPA is mediated by single-stranded DNA binding and protein interactions (By similarity). Heterotrimer of RPA1, RPA2 and RPA3 (canonical replication protein A complex) (By similarity). Interacts with RPA1A and RPA3. Phosphorylated in a cell-cycle-dependent manner (from the S phase until mitosis). In response to DNA damage, recruited to DNA-repair nuclear foci, as a hypophosphorylated form (By similarity). Belongs to the replication factor A protein 2 family.