Possible role in ribosomal RNA processing. May function as a substrate receptor for CUL4-DDB1 E3 ubiquitin-protein ligase complex (By similarity). Protein modification; protein ubiquitination. Interacts with DDB1. Interacts with ESR1 and LATS1. In the nucleolus, localizes predominantly in the granular component, but also detected in the fibrillar center and dense fibrillar component. Belongs to the WD repeat DCAF13/WDSOF1 family.