Desensitization to alpha-factor pheromone. Is involved in regulating the signaling pathway for responding to mating pheromone. By exposure to pheromone. The fungal-differentiation regulator (Fungal-DR) domain is only found in fungal regulator of G-protein signaling (RGS) proteins that regulate differentiation pathways. It is required for function (By similarity). Phosphorylated by FUS3 and KSS1. Present with 5980 molecules/cell in log phase SD medium.