Catalyzes the reversible transfer of high energy ATP gamma-phosphate group to L-arginine. ATP + L-arginine = ADP + H(+) + N(omega)-phospho-L-arginine Muscle (at protein level). Glycosylated. Causes an allergic reaction in human. Binds to IgE of crab-allergic patients (PubMed:23911402, PubMed:25728640, PubMed:30236721). Binds to IgE in 89% of the 9 patients tested allergic to crab (PubMed:23911402). Causes degranulation of rat basophilic leukemia (RBL) cells and release of beta-hexosaminidase from them. Allergenicity is affected to different degrees by denaturants. SDS reduces allergenicity at low concentrations (0.3 mM), and allergenicity is almost completely abolished with 15 mM SDS. Urea concentrations of 2.0-3.0 M enhance allergenicity, whereas at concentrations higher than 4.0 M, the allergenicity is reduced. Slight change in allergenicity after guanidinium chloride (GdnHCl) treatment, but when concentration of GdnHCl reaches 1.5 M, the allergenicity is unchanged. DTT (disulfide bond-reducing agent), at a concentration of 10 mM, causes a slight reduction in allergenicity and it is decreased in a dose-dependent manner at concentrations of 10-250 mM, but remains steady at higher concentrations. 2.5 M beta-mercaptoethanol (another disulfide bond-reducing agent) treatment reduces allergenicity (PubMed:25728640). Belongs to the ATP:guanido phosphotransferase family.