F-box-like protein which acts as an integral component of the N-CoR transcriptional corepressor complex. Probably regulates transcription activation mediated by nuclear receptors. May mediate the recruitment of the 19S proteasome complex, leading to the subsequent proteasomal degradation of the N-CoR complex, thereby allowing cofactor exchange and transcription activation (By similarity). Interacts with heterodimers of rxra and thrb, and this interaction is abrogated by thyroid hormone binding to thrb. Interacts with ncor1. Expressed in the developing intestine both prior to and during remodeling (stages NF54 to NF66). The F-box-like domain is related to the F-box domain, and also functions to recruit ubiquitin E3 ligase complexes. Belongs to the WD repeat EBI family.