Required for cytoplasmic lattice formation, thereby modulates the distribution of organelles during oocyte maturation and zygote development (PubMed:31575650). Required for preimplantation development in female fertility (PubMed:31575650). May be involved in inflammation and recognition of cytosolic pathogen-associated molecular patterns (PAMPs) not intercepted by membrane-bound receptors (By similarity). Associates with the subcortical maternal complex (SCMC) composed of at least NLRP5, KHDC3, OOEP, and TLE6 via interaction with OOEP and TLE6. Expressed and colocalizes with NLRP5 at the oocyte subcortex. Expressed in the ovaries (at protein level). Abundantly expressed in one-cell stage embryos with decreasing expression in the morula stage, expression in the blastocyst is considerably lower (PubMed:31575650). Expressed in the ovaries from birth, expression peaks at postnatal day 10 (P10), expression is then decreased at P17 and further decreased at P21 (PubMed:31575650). No visible phenotype, however female mice produce fewer offspring. Delay in embryo compaction and blastocyst cavitation (PubMed:31575650). Disorganization of the mitochondria in zygotes around the pronucleus and subcortical region following nuclear envelope breakdown. During oocyte maturation the endoplasmic reticulum and mitochondria are aberrantly distributed in the nucleus and cortical region at the germinal vesicle stage, in the subcortical region after germinal vesicle break down and dispersed throughout the cytoplasm at the M2 stage (PubMed:31575650). Loss of cytoplasmic lattices in oocytes (PubMed:31575650). Belongs to the NLRP family.