Receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the receptor binds to a promoter element in the gene for acyl-CoA oxidase and activates its transcription. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. May play a role in the regulation of circadian rhythm (By similarity). Heterodimer with the retinoid X receptor. Expressed mainly in adipose tissue and kidney. Adult. The 9aaTAD motif is a transactivation domain present in a large number of yeast and animal transcription factors. Belongs to the nuclear hormone receptor family. NR1 subfamily.