Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors (such as IF-2, EF-Tu, EF-G and RF3). Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and 23S rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a pentameric L10(L12)2(L12)2 complex. In response to low temperature and salt stress. Isolated L10(L12)4. Isolated L10(L12)4. Belongs to the universal ribosomal protein uL10 family.