UDPGT is of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds. glucuronate acceptor + UDP-alpha-D-glucuronate = acceptor beta-D-glucuronoside + H(+) + UDP A number of isoforms are produced. The different isozymes have a different N-terminal domain and a common C-terminal domain of 245 residues. Expressed in kidney. Belongs to the UDP-glycosyltransferase family.