Induces expression of IL6, CXCL8/IL8, and CSF2/GM-CSF from endothelial cells. Expressed preferentially in adipose, skeletal muscle and CNS. Belongs to the IL-17 family. IL17D nucleotide sequence has been submitted under the name IL27 in INSDC AY078238 (Ref.2). However, the protein shown in this entry should not be confused with the actual IL27 protein, which forms a heterodimeric cytokine by interaction with EBI3. In order to avoid any ambiguity, we strongly recommend using the official HGNC nomenclature. Interleukin-17 entry