Induces proliferation of human neuroblastoma cells but not of human colonic epithelial cells or human adrenal carcinoma cells (PubMed:24796676). Also increases proliferation of mouse neural stem cells (PubMed:26215270). In human neuroblastoma cells and mouse neural stem cells, inhibits apoptosis induced by the synthetic neurotoxic compound 6-hydroxydopamine (6-OHDA) (PubMed:24796676). In human neuroblastoma cells and mouse neural stem cells, increases ubiquitination of cyclin-dependent kinase inhibitor CDKN1B, promoting its degradation (PubMed:24796676, PubMed:26215270). Attenuates motor impairments in 6-OHDA-treated mice (PubMed:26215270).