Receptor for the neuroprotective and glioprotective factor prosaposin. Ligand binding induces endocytosis, followed by an ERK phosphorylation cascade (By similarity). Forms a complex with PRKN, STUB1 and HSP70. The amount of STUB1 in the complex increases during ER stress. STUB1 promotes the dissociation of HSP70 from PRKN, thus facilitating PRKN-mediated GPR37 ubiquitination. Interacts with PACRG (By similarity). Highly expressed in the brain. High levels of expression were seen in fiber tracts such as the corpus callosum, anterior commissure, fornix, internal capsule, cerebral peduncles, and stria terminalis. Additionally, moderate levels of expression were seen in the pyramidal tracts and cerebellar peduncles, as well as in the spinal tract of the trigeminal nerve and the spinal fasciculi. Ubiquitinated by PRKN in the presence of ubiquitin-conjugating enzymes in the endoplasmic reticulum. Belongs to the G-protein coupled receptor 1 family.