Antimicrobial peptide that shows antimicrobial activities against all microorganisms tested with minimal inhibitory concentrations (MICs) values ranging from 0.45 to 97.5 umol/L (PubMed:27058430). This peptide kills the microorganisms by permeabilizating the membranes (PubMed:27058430). It shows a very weak hemolytic activity (HC(50)=325 umol/L) and weak cytotoxicity against human lymphocytes (LC(50)=67.8 umol/L) (PubMed:27058430, PubMed:22960382). Gram-negative bacteria tested are E.coli (MIC=24.4 umol/L), C.sakazakii (MIC=5.8 umol/L), P.aeruginosa (MIC=8.7-12.2 umol/L), S.enterica (MIC=5.4 umol/L), and H.pylori (MIC=0.99-3.9 umol/L) (PubMed:22960382, PubMed:29286296). Gram-positive bacteria tested are E.hirae (MIC=12.2 umol/L), S.aureus (MIC=3.0-6.4 umol/L), methicillin-resistant S.aureus (MRSA) (MIC=8.7 umol/L), S.xylosus (MIC=0.45-1.3 umol/L), and B.subtilis (MIC=24.4 umol/L) (PubMed:27058430, PubMed:22960382). Fungi tested are A.niger (MIC=0.75 umol/L), C.albicans (MIC=17.3 umol/L), G.candidum (MIC=97.5 umol/L), and S.cerevisiae (MIC=6.1 umol/L) (PubMed:27058430). Finally the parasite tested is L.infantum (MIC=1.5 umol/L) (PubMed:27058430). Forms a helical membrane channel in the prey. Expressed by the venom gland. The C-terminal amidation is important for antimicrobial activity, since a non-amidated synthetic peptide shows a reduced antimicrobial activity (2-20-fold depending on the strain tested). The amidation may play a positive role in the peptide conformation, since amidated peptide shows an increase of about 5% of helical content. This is the most abundant peptide from the venom of T.bicarinatum. Belongs to the formicidae venom precursor-01 superfamily.