Phosphodiesterase with dual cAMP/cGMP specificity. However, displays a preference for cAMP over cGMP. Seems to regulate cAMP/cGMP concentration especially during cell aggregation. 3',5'-cyclic AMP + H2O = AMP + H(+) 3',5'-cyclic GMP + H2O = GMP + H(+) Inhibited by dithiotreitol (DTT). Down-regulated by growth on bacteria. Belongs to the cyclic nucleotide phosphodiesterase class-II family.