Extremely potent and selective inhibitor of integrin alpha-5/beta-1 (ITGA5/ITGB1). Partially inhibits adhesion of cells expressing alpha-IIb/beta-3 (ITGA2B/ITGB3), alpha-V/beta-3 (ITGAV/ITGB3), and alpha-4/beta-1 (ITGA4/ITGB1) to appropriate ligands only at concentration higher than 500 nM. Weakly inhibits ADP-induced platelet aggregation. Heterodimer with EMF10B; disulfide-linked. Expressed by the venom gland. Belongs to the disintegrin family. Dimeric disintegrin subfamily. Eristocophin I appears to represent degradation product of EMF10A.