NAD(+)-dependent alcohol dehydrogenase. a primary alcohol + NAD(+) = an aldehyde + H(+) + NADH a secondary alcohol + NAD(+) = a ketone + H(+) + NADH Binds 2 Zn(2+) ions per subunit. Substrate inhibition is not observed with any alcohols, and the enzyme-NADH dissociation is not considered to be a rate-limiting step. Thermostable. Belongs to the zinc-containing alcohol dehydrogenase family.