Adapter protein for the cul3 E3 ubiquitin-protein ligase complex. Promotes the export of zbtb16/plzf from the nucleus to the cytoplasm and targets zbtb16/plzf for ubiquitination and degradation. Up-regulates neurog1 expression and antagonizes zbtb16/plzf, to promote neurogenesis (By similarity). Interacts with cul3. Interacts (via BTB domain) with zbtb16/plzf (By similarity). Present mainly, but not excusively in the cytoplasm. In embryos, expressed in the cranial ganglia.