Involved in coupling signal transduction and vesicle trafficking to enable polarized secretion and/or membrane deposition of immune effector molecules (By similarity). Involved in phagophore growth during mitophagy by regulating ATG9A trafficking to mitochondria (PubMed:33773106). Ubiquitous. By bacterial lipopolysaccharides (LPS). The disease is caused by variants affecting the gene represented in this entry. Was originally said to be similar to yeast CDC4, but that similarity is very limited.