Alpha-conotoxins act on postsynaptic membranes, they bind to the nicotinic acetylcholine receptors (nAChR) and thus inhibit them. This conotoxin is a subtype-specific blocker of alpha-6/alpha-3-beta-2-beta-3 (CHRNA6/CHRNA3-CHRNB2-CHRNB3) nAChRs nicotinic acetylcholine receptors (nAChRs) (IC(50)=28.4 nM). Expressed by the venom duct. The cysteine framework is I (CC-C-C). Alpha4/7 pattern. Does not affect the following neuronal AChR: alpha-6/alpha-3 beta-4 (CHRNA6/CHRNA3 CHRNB4), rat alpha-7 (CHRNA7), alpha-9 alpha-10 (CHRNA9 CHRNA10), alpha-2 beta-2 (CHRNA2 CHRNB2), alpha-2 beta-4 (CHRNA2 CHRNB4), alpha-3 beta-2 (CHRNA3 CHRNB2), alpha-3 beta-4 (CHRNA3 CHRNB4), alpha-4 beta-2 (CHRNA4 CHRNB2), alpha-4 beta-4 (CHRNA4 CHRNB4), nor the muscle receptor alpha-1 beta-1 delta epsilon (CHRNA1 CHRNB1 CHRNE CHRND). Belongs to the conotoxin A superfamily.