Gamma chains make up the fetal hemoglobin F, in combination with alpha chains. Heterotetramer of two alpha chains and two gamma chains in fetal hemoglobin (Hb F). Red blood cells. Expressed until four or five weeks after birth. Acetylation of Gly-2 converts Hb F to the minor Hb F1. The disease is caused by variants affecting the gene represented in this entry. Belongs to the globin family. Extended N-terminus. Human hemoglobin variants and thalassemias