Component of the RIX1 complex required for processing of ITS2 sequences from 35S pre-rRNA and the nucleoplasmic transit of the pre-60S ribosomal subunits (PubMed:11313466, PubMed:14759368, PubMed:15528184, PubMed:26619264). Regulates pre-60S association of the critical remodeling factor MDN1 (PubMed:26619264). Component of the RIX1 complex, composed of IPI1, RIX1/IPI2 and IPI3 in a 1:2:2 stoichiometry. The complex interacts (via RIX1) with MDN1 (via its hexameric AAA ATPase ring) and the pre-60S ribosome particles (PubMed:14690591, PubMed:14759368, PubMed:15260980, PubMed:15528184, PubMed:26619264). Interacts with NUG1 (PubMed:11583615). Interacts with IPI3 (PubMed:14690591). Sumoylated. Present with 7820 molecules/cell in log phase SD medium. Belongs to the RIX1/PELP1 family.