Involved in formation and maintenance of cell shape. Required for the formation of proper helical filaments of MreB and for cell wall synthesis in the cylindrical part of the cell leading to cell elongation. Self-associates. Interacts with MreD and proteins that belong to class A and class B high-molecular-weight penicillin-binding proteins (PBP2b, PBP1, PBP2a, PBP3, PBP4, PBP2c, PBP2d, PBPH and PBP4b). Localizes in helical patterns when associated with the cell membrane (PubMed:15745453). Present in detergent-resistant membrane (DRM) fractions that may be equivalent to eukaryotic membrane rafts; these rafts include proteins involved in signaling, molecule trafficking and protein secretion (PubMed:22882210). Loss of viability. Cells lacking sufficient quantities of this protein undergo morphological changes, namely, swelling and twisting of the cells followed by cell lysis. A polymeric material accumulates at one side of the division septum of the cells and the presence of this material correlates with the bending of the cell. After prolonged depletion in the presence of MgCl(2), the cells become very short and fat and eventually spheroidal, but no significant lysis is observed. Addition of sucrose results in rounded cells. Cells are still capable of making division septa. Null mutants show little or no sign of a defined long axis and have a severe shape defect. Belongs to the MreC family.