Gamma-conotoxins may act on voltage-gated non-specific cation pacemaker channels (HCN) (By similarity). Elicits toxic effects in the freshwater snail Pomacea paludosa after intramuscular injection, but it has no effect when injected intracerebrally into mice. Expressed by the venom duct. The presence of a 'disulfide through disulfide knot' structurally defines this protein as a knottin. The cysteine framework is VI/VII (C-C-CC-C-C). Decarboxylated. Belongs to the conotoxin O1 superfamily.