Calcium/calmodulin-dependent protein kinase (PubMed:2835766). Required in nuclear division cycle for progression from G2 to mitosis. Required for hyphal growth (PubMed:8898358). ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein] ATP + L-threonyl-[protein] = ADP + H(+) + O-phospho-L-threonyl-[protein] Activated by Ca(2+)/calmodulin (PubMed:8898358). Binding of calmodulin may relieve intrasteric autoinhibition (Probable). Monomer. The autoinhibitory domain overlaps with the calmodulin binding region and interacts in the inactive folded state with the catalytic domain as a pseudosubstrate. Autophosphorylated in a calcium/calmodulin-dependent manner. Spores arrest with a single nucleus and fail to extend a germ tube. Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. CaMK subfamily.