diphosphate + H2O = H(+) + 2 phosphate Has high activity in the presence of Zn(2+), Mn(2+), Cu(2+), Fe(2+) or Co(2+) ions. In the absence of metal ions, there is no activity. Inhibited by ATP, fructose 1,6-bisphosphate and 2-phosphoglycerate. Homododecamer. Belongs to the PPase family.