Neurotensin may play an endocrine or paracrine role in the regulation of fat metabolism. It causes contraction of smooth muscle (By similarity). Interacts with NTSR1. Interacts with SORT1. Interacts with SORL1. Packaged within secretory vesicles. Neurotensin is cleaved and degraded by Angiotensin-converting enzyme (ACE) and neprilysin (MME). Belongs to the neurotensin family.