Probable transcription factor that plays a role in configuring the spinal circuits controlling stride in vertebrates. Involved in neuronal specification within specific subdivision of spinal cord neurons and in the development of a coordinated locomotor network controlling limb movements. May regulate transcription during sexual development. Expressed in the ventral spinal cord, in a restrical population of neurons migrating ventrically in the developing spinal cord at 11.5 dpc. Expressed at 14.5 dpc in testis, kidney and bladder. Expression drops at 13.5 dpc in female gonads and is not detected at 15.5 dpc while it is expressed by Sertoli cells in testis. DMA domain interacts with ubiquitin. Significantly increase of stride length and extension movements in all limbs. Mice have major difficulties running at higher velocities. In water, mice spend less time swimming and showed frequent twitching limb movements. DMRT3 is a marker for a subset of spinal cord neurons (dI6). Belongs to the DMRT family. A gait on the wildside - Issue 154 of November 2013