Plays a role into cellular response to oxidative stress. Decreases cell proliferation. Interacts with GAPDH and STAT1. Expressed in the glioblastoma cell line U-87MG, the embryonic kidney cell line HEK293, the pancreatic carcinoma cell line PANC-1, the breast carcinoma cell line MCF-7, the lung cancer cell line NCI-H460, and the chronic myelogenous leukemia cell line K-562. Belongs to the EIF1AD family.