Involved in stress signaling pathway that mediates cell death in response to endoplasmic reticulum (ER) stress and osmotic stress. Induced by infection with an avirulent strain of the bacterial pathogen Pseudomonas syringae pv glycinea (Ref.1). Induced by infection with the fungal pathogen Phytophtora sojae (Ref.1). Induced by copper, cycloheximide and reduced glutathione (Ref.1). Induced by tunicamycin, azetidine-2-carboxylate (AZC) and osmotic stress (PubMed:18490446, PubMed:18036212). Induced by dithiothreitol (DTT) (PubMed:18490446). Induced by wounding (PubMed:21482825). Overexpression of NRP in protoplasts induces caspase-3-like activity and promotes extensive DNA fragmentation (PubMed:18490446). Transient expression of NRP in planta causes leaf yellowing, chlorophyll loss, malondialdehyde production, ethylene accumulation, and induction of the senescence marker gene CP1 (PubMed:18490446).