Pre-mRNA processing factor involved in disassembly of spliceosomes after the release of mature mRNA. ATP + H2O = ADP + H(+) + phosphate Component of the NTR complex (NTC-related complex), composed of NTR1, NTR2 and PRP43. Interacts with NTR1 and NTR2. Interacts with SPP382. Present with 16900 molecules/cell in log phase SD medium. Belongs to the DEAD box helicase family. DEAH subfamily. DDX15/PRP43 sub-subfamily.