May be responsible for the metabolism of many drugs and environmental chemicals that it oxidizes. It may be involved in the metabolism of codeine to morphine (PubMed:15051713). However, another study could not confirm it (PubMed:18838503). an organic molecule + O2 + reduced [NADPH--hemoprotein reductase] = an alcohol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase] Expressed in brain cortex (at protein level). A rare double polymorphism may allow the expression of a functional protein (PubMed:15051713). However, following studies could not confirm the combined existence of both polymorphisms and therefore question the existence of that protein (PubMed:16169517, PubMed:17494644). Belongs to the cytochrome P450 family. Could be the product of a pseudogene.