Dipeptidase that hydrolyzes leukotriene D4 (LTD4) into leukotriene E4 (LTE4) (PubMed:32325220). Hydrolyzes cystinyl-bis-glycine (PubMed:32325220). Independently of its dipeptidase activity can also modulate macrophage inflammatory response by acting as a regulator of NF-kappaB inflammatory signaling pathway. an L-aminoacyl-L-amino acid + H2O = 2 an L-alpha-amino acid H2O + leukotriene D4 = glycine + leukotriene E4 2 H2O + L-cystine-bis-glycine = 2 glycine + L-cystine Inhibited by L-penicillamine. Homodimer; disulfide-linked. Belongs to the metallo-dependent hydrolases superfamily. Peptidase M19 family. Truncated N-terminus.