Performs an essential function in the generation of cytoplasmic iron-sulfur proteins by mediating the ATP-dependent export of Fe/S cluster precursors synthesized by nfs1 and other mitochondrial proteins (PubMed:16306692). Hydrolyzes ATP (By similarity). Binds glutathione and may function by transporting a glutathione-conjugated iron-sulfur compound (By similarity). Homodimer. Abnormal mitochondrial function; decreases growth on glycerol (non-fermentable carbon source) (PubMed:16306692). Abnormal endocytosis and vacuole fusion (PubMed:16306692). Sensitive to copper, and dithiothreitol (PubMed:16306692). Belongs to the ABC transporter superfamily. ABCB family. Heavy Metal importer (TC 3.A.1.210) subfamily.