Component of the HIR complex, which cooperates with ASF1 to promote replication-independent chromatin assembly. The HIR complex is also required for the periodic repression of three of the four histone gene loci during cell cycle as well as for autogenous regulation of the HTA1-HTB1 locus by H2A and H2B. DNA-binding by the HIR complex may repress transcription by inhibiting nucleosome remodeling by the SWI/SNF complex. The HIR complex may also be required for transcriptional silencing of centromeric, telomeric and mating-type loci in the absence of CAF-1. Component of the HIR complex, composed of HIR1, HIR2, HIR3 and HPC2 (PubMed:16264190, PubMed:16303565, PubMed:9001207, PubMed:9504914). This complex may consist of one copy of HIR1 and HIR3 and two copies of HIR2 and HPC2 (PubMed:16264190). The HIR complex interacts with ASF1 (PubMed:11404324, PubMed:11412995). Interacts with SNF2 (PubMed:10445029). Interacts with SNF5 (PubMed:10445029). Interacts with SWI3 (PubMed:10445029). Interacts with RTT106 (PubMed:19683497). May interact with SPT4 (PubMed:9504914). May self-associate (PubMed:9504914). Enriched at centromeres (PubMed:11782447). Localizes to the promoter region of histones HTA1-HTB1, HHT1-HHF1, and HHT2-HHF2, (PubMed:19683497). Decreases nucleosomal density (PubMed:19683497). Increases HTA1 RNA level; simultaneous disruption RTT109 alleviates the effect (PubMed:19683497). Abolishes localization of RTT106 to the HTA1-HTB1 promoter (PubMed:19683497). Present with 846 molecules/cell in log phase SD medium. Belongs to the WD repeat HIR1 family.