The dialkylglycine decarboxylase is of interest because it normally catalyzes both decarboxylation and amino transfer. It may be more properly described as a decarboxylating aminotransferase rather than an aminotransferring decarboxylase. 2,2-dialkylglycine + H(+) + pyruvate = CO2 + dialkyl ketone + L-alanine Homotetramer. The enzyme may have evolved to use the rare dialkylglycines of cosmic origin, or it may be part of a metabolic pathway for breaking down cytotoxic peptides and the constituent amino acids. Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.