Induces angiogenesis, probably through VEGF receptor (KDR/VEGFR-2) signaling, as well as drastic hypotension. The hypotension is mediated by nitric oxide (NO), which is produced by VEGF-activated endothelium NO synthase. Increases capillary permeability when injected intradermally into rat. Homodimer; disulfide-linked. Interacts with VEGF receptor-2 (KDR) with high affinity, but not with VEGF receptor-1 (Flt-1), VEGF receptor-3 (FLT4), and neuropilin-1 (NRP1). Expressed by the venom gland. Belongs to the PDGF/VEGF growth factor family. Snake venom VEGF subfamily.