May be involved in the growth pathway. Defect in TMEM263 may be a one of the causes of autosomal recessive dwarfism in Cornell K-strain white leghorns. A nonsense mutation truncates the protein and probably cause a dysfunctional protein. Autosomal dwarf chicken display small body stature by short shank length, with 30-40% reduced adult body weight despite normal hormonal concentration of GH and IGF1. Belongs to the TMEM263 family.