Plays a role in lysosome motility. In neurons, mediates the anterograde axonal long-range transport of presynaptic lysosome-related vesicles required for presynaptic biogenesis and synaptic function (By similarity). May play a role in chromosome segregation (By similarity). Localizes with microtubules at the spindle mid-zone during mitosis. Belongs to the small GTPase superfamily. Arf family.