Component of the nexin-dynein regulatory complex (N-DRC) a key regulator of ciliary/flagellar motility which maintains the alignment and integrity of the distal axoneme and regulates microtubule sliding in motile axonemes. May play a role in the assembly of N-DRC (By similarity). Required for sperm motility (PubMed:28630322). Component of the nexin-dynein regulatory complex (N-DRC) Interacts with FBXL13/DRC6, DRC3 and DRC7 (PubMed:28630322, PubMed:31961863). Detected along the length of the sperm flagellum. Testis-specific (at protein level). Male mice are sterile due to asthenozoospermia (sperm with diminished progressive motility) and the diminished motility is due to aberrant flagellar function, with sperm tails contracting toward one side and generating a circular path for sperm. Belongs to the DRC5 family.