In a heterologous system, involved in cadmium and lead transport, but not in zinc transport. May have a detoxification function through a vacuolar sequestration. ATP + H2O + Zn(2+)(in) = ADP + H(+) + phosphate + Zn(2+)(out) ATP + Cd(2+)(in) + H2O = ADP + Cd(2+)(out) + H(+) + phosphate Tonoplast. Roots, stems, leaves and flowers. Not induced by cadmium or zinc treatments. Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily. In cv. Columbia (AC P0CW77), a naturally occurring frameshift at position 543 results in a shortened C-terminus. The sequence shown is from strain cv. Wassilewskija.