MFS-type efflux pump involved in the modulation susceptibility to azoles, including fluconazole, itraconazole, miconazole and voriconazole (Ref.2). Confers also increased resistance chloramphenicol and thiamphenicol, suggesting that it acts as a pleiotropic drug transporter with a broad substrate spectrum (Ref.2). Finally, increases the tolerance to cycloheximide when expressed in S.cerevisiae, but not in dermatophyte species (Ref.2). Leads to decreased tolerance to the azoles fluconazole, itraconazole, voriconaole, miconazole, as well as to the antibiotics chloramphenicol and thiamphenicol. Belongs to the major facilitator superfamily. TCR/Tet family. Extended N-terminus.