Mediates NRF1-enhanced neurite outgrowth. Interacts with ATG8 family modifier proteins MAP1LC3A, MAP1LC3B, GABARAP and GABARAPL1. Mainly expressed in the central nervous system and in parenchymatous organs including liver, lung and kidney. The LIR motif interacts with ATG8 family proteins. Belongs to the RETREG family.