Component of adherens-type cell-cell and cell-matrix junctions (PubMed:8175905). Has no phosphoglucomutase activity in vitro (PubMed:8175905). Interacts with DMD/dystrophin; the interaction is direct (By similarity). Interacts with UTRN/utrophin (By similarity). Concentrated in focal contacts at the ends of actin bundles, and associated with actin filaments. Detected in smooth and cardiac muscle at high levels and in skeletal muscle at low level. Present in other tissues due to vascular or other smooth muscle component. Low levels are present in liver, kidney, skin and brain (at protein level). In the developing aorta, expressed at low levels in 10-12 week old fetuses. Levels increase progressively in 24 week fetus, 6 month old child and 1.5 year old child aortic smooth muscle, reaching a maximum at maturity. Belongs to the phosphohexose mutase family.