Recombinant disintegrin rubistatin inhibits ADP-induced platelet aggregation. In addition, it strongly induces apoptosis, and inhibits cell migration and proliferation of the human cancer cell line SK-Mel-28. Monomer. Expressed by the venom gland. Does not induce chromatin fragmentation (apoptosis) in T24 and HeLa cells. The disintegrin belongs to the medium disintegrin subfamily. Belongs to the venom metalloproteinase (M12B) family. P-II subfamily. P-IIa sub-subfamily.