Component of the RACK1 regulatory proteins that functions in innate immunity by interacting with multiple proteins in the RAC1 immune complex. Acts as positive regulator of reactive oxygen species (ROS) production and is required for resistance against rice blast (M.grisea) infection. Interacts with RAC1, RAC3, RAC6, RAR1, SGT1 and RBOHB. Homodimer and heterodimer with RACK1B (Probable). Predominantly found in the cytoplasm. Widely expressed. By auxin, abscisic acid (ABA) and jasmonic acid (JA). Belongs to the WD repeat G protein beta family. Ribosomal protein RACK1 subfamily.