Involved in the metabolism of aromatic oximes. Catalyzes the oxime metabolizing step in indole glucosinolate biosynthesis by converting indole-3-acetaldoxime into indole-3-S-alkyl-thiohydroximate. Probably required for glucosinolate activation in response to pathogens. Functions in auxin homeostasis because indole-3-acetaldoxime also serves as a precursor for auxin biosynthesis. Specifically metabolizes (E)-p-hydroxyphenylacetaldoxime into an S-alkyl-thiohydroximate (PubMed:26361733). (E)-(indol-3-yl)acetaldehyde oxime + glutathione + O2 + reduced [NADPH--hemoprotein reductase] = (E)-1-(glutathione-S-yl)-2-(1H-indol-3-yl)acetohydroximate + H(+) + 2 H2O + oxidized [NADPH--hemoprotein reductase] (E)-phenylacetaldehyde oxime + glutathione + O2 + reduced [NADPH--hemoprotein reductase] = (Z)-1-(glutathione-S-yl)-2-phenylacetohydroximate + H(+) + 2 H2O + oxidized [NADPH--hemoprotein reductase] kcat is 52 min(-1) with indole-3-acetaldoxime as substrate. kcat is 14 min(-1) with p-hydroxyphenylacetaldoxime as substrate. kcat is 47 min(-1) with phenylacetaldoxime as substrate. By auxin and continuous red light. Stimulated by DOF1.1 and, transiently, by the generalist herbivore S.littoralis (PubMed:16740150). Runt phenotype (small plants with hooked leaves). Epinastic leaves and defect in root development. High levels of endogenous free auxin. Altered tryptophan genes regulation. The sur2 mutant phenotype can be complemented by exogenous auxin or low pH medium. Plants overexpresseing SUR2 show decreased apical dominance. Belongs to the cytochrome P450 family.