Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity). Plays a role in the physiological regulation of the intracellular CoA concentration. (R)-4'-phosphopantetheine + ATP + H(+) = 3'-dephospho-CoA + diphosphate Present with 3610 molecules/cell in log phase SD medium. Belongs to the eukaryotic CoaD family.