Transcription factor that acts as a cardiac regulator and an effector of alpha1-adrenergic signaling. Binds to PE response elements (PERE) present in the promoter of genes such as ANF/NPPA and acts as a direct transcriptional activator of NPPA. Also acts as a cofactor with GATA4, a key cardiac regulator (By similarity). Binds DNA. Interacts with GATA4 (By similarity). Up-regulated by activation of alpha1-adrenergic receptors. Belongs to the krueppel C2H2-type zinc-finger protein family. It is uncertain whether Met-1 or Met-4 is the initiator.