May act by engaging a cell surface molecule on immature T-cells in the embryonic thymus. Expressed in the thymus and skin. All hominoid species have a common inactivating mutation, but that Old World monkeys such as olive baboons, green monkeys, cynomolgus macaques and rhesus macaques have apparently functional SKINT1L sequences, indicating that SKINT1L is inactivated in a common ancestor of hominoids. Belongs to the SKINT family.