May mediate the cellular interaction between myeloid cells and B-cells. Forms a heterodimer, consisting of a large extracellular region (alpha subunit) non-covalently linked to a seven-transmembrane moiety (beta subunit). Predominantly expressed in myeloid cells. Predominantly expressed on resident macrophages. Up-regulated following macrophage activation. The second EGF domain mediates the interaction with the putative ligand. Proteolytically cleaved into 2 subunits, an extracellular alpha subunit and a seven-transmembrane subunit. Glycosylated. Belongs to the G-protein coupled receptor 2 family. Adhesion G-protein coupled receptor (ADGR) subfamily.