G-protein coupled receptor for tyramine, a known neurotransmitter and neuromodulator and direct precursor of octopamine. The rank order of potency for agonists of this receptor is tyramine > naphazoline > tolazoline > DL-octopamine > dopamine > epinephrine > 5-hydroxytryptamine. For antagonists, the rank order is yohimbine > chlorpromazine > mianserin > phentolamine > metoclopramide. Present mainly in the central nervous system, especially in the supra- and subesophageal, thoracic and abdominal ganglia. Not found in the distal part of optic lobes. Expressed in the nervous system by the first larval stage. Belongs to the G-protein coupled receptor 1 family.