Regulates coat complex coatomer protein I (COPI)-independent Golgi-endoplasmic reticulum transport by recruiting the dynein-dynactin motor complex. Interacts with RAB6A. Interacts (via C-terminus) with RAB6B (GTP-bound); the interaction is direct (By similarity). Interacts with CLIP-115 and KIFC2. Expressed in the brain, heart and skeletal muscle. Expressed during embryonic development. Due to intron retention. Due to intron retention. Belongs to the BicD family.