Plays a role in mitotic exit and cytokinesis. Recruits PDCD6IP and TSG101 to midbody during cytokinesis. Required for successful completion of cytokinesis. Not required for microtubule nucleation (By similarity). Plays a role in the development of the brain and kidney (PubMed:28264986). Morpholino knockdown of the protein increases jaw cartilage disorganization, decreases the size of brain structures and the lateral area and convolution of proximal renal tubules at 4 days post-fertilization (dpf) (PubMed:28264986). Embryos with CRISPR-induced cep55l null mutations display altered craniofacial patterning and atrophy of the proximal renal tubules (PubMed:28264986).