Associates with microtubules and may play a role in the microtubule-dependent transport of the GABA-B receptor. May play a role in JAK1 signaling and regulate microtubule cytoskeleton rearrangements. Homodimer (By similarity). Interacts with JAK1 and TYK2 (By similarity). Forms a complex with GABBR1 and KIF5B/kinesin-1. Colocalizes with the microtubule network. Localizes to the cell body and neurites of hippocampal neurons where it accumulates in granules. Localizes to the tail and to a lower extent to the head of sperm cells (By similarity). Phosphorylated. Belongs to the JAKMIP family.