Acts as a Mg(2+) transporter. Can also transport other divalent cations such as Ba(2+), Mn(2+), Sr(2+) and Co(2+) but to a much less extent than Mg(2+) (By similarity). May be a receptor for ligands (trioxilins A3 and B3) from the hepoxilin pathway. Highly expressed in brain, lung, stomach, keratinocytes and leukocytes, and in all other tissues tested except liver, thyroid and fetal brain. The disease is caused by variants affecting the gene represented in this entry. Belongs to the NIPA family. Extended N-terminus. Extended N-terminus. Extended N-terminus. Protein truncation is due to an exon 5 splice site mutation which is found in a ARCII patient. Extended N-terminus.