Alpha-conotoxins act on postsynaptic membranes, they bind to the nicotinic acetylcholine receptors (nAChR) and thus inhibit them. This toxin weakly inhibits alpha-9-alpha-10/CHRNA9-CHRNA10 nAChRs (IC(50)=3 uM). Expressed by the venom duct. The cysteine framework is XXVIII (C-C-C-CC-C-C-C-C-C). Contains 5 disulfide bonds. Very weakly inhibits alpha-3-beta-2/CHRNA3-CHRNB2 (19.4% when 10 uM of toxin is tested) and alpha-4-beta-2/CHRNA4-CHRNB2 (18% at 10 uM) nAChRs subtypes. Has no effect on alpha-3-beta-4/CHRNA3-CHRNB4, alpha-4-beta-4/CHRNA4-CHRNB4, alpha-2-beta-2/CHRNA2-CHRNB2, alpha-2-beta-4/CHRNA2-CHRNB4, alpha-7/CHRNA7 and alpha-6/alpha-3-beta-2-beta-3 (CHRNA6/CHRNA3-CHRNB2-CHRNB3) nAChRs subtypes. Belongs to the conotoxin D superfamily.