Component of the SEA complex which coats the vacuolar membrane and is involved in intracellular trafficking, autophagy, response to nitrogen starvation, and amino acid biogenesis (PubMed:21454883). Mediates inactivation of the TORC1 complex in response to amino acid starvation (PubMed:19521502, PubMed:26510498). Post-transcriptional regulator of nitrogen permeases (PubMed:19521502). May be involved in putative NPR1-dependent phosphorylation of nitrogen permeases or in the processing and targeting of nitrogen permeases at the level of the endoplasmic reticulum (PubMed:19521502). Component of the SEA complex composed of at least IML1/SEA1, RTC1/SEA2, MTC5/SEA3, NPR2, NPR3, SEA4, SEC13 and SEH1. Forms a heterodimer with NPR3. By urea and proline. TORC1 abnormally activated in presence of rapamycin. Present with 319 molecules/cell in log phase SD medium. Belongs to the NPR2 family. Extended N-terminus. Extended N-terminus. Extended N-terminus.