Orphan receptor that plays a role in vessel formation. During gastrulation, expression is ubiquitously detected throughout the embryo. During development is detected in epithelial cells, blood precursor cells and developing vessels. By 48 hpf, weaker expression is still detected in epithelials cells. Morpholino knockdown of the protein causes dramatic vascular impairment in embryos. Belongs to the G-protein coupled receptor 2 family. Adhesion G-protein coupled receptor (ADGR) subfamily.