Required for the cessation of distal tip cell migration at the end of larval morphogenesis. Predominantly nuclear localization in the distal tip cell. Expressed in the intestine, nervous system and head neurons in both larvae and adults (PubMed:17850180). Expressed in the distal tip cell (PubMed:22285439). Early larval arrest, continued gonad expansion and shortened lifespan. RNAi-mediated knockdown results in continuous distal tip cell migration past the midline during adulthood. In a rnf-5(tm794) mutant background, increased severity of the distal tip cell migration defects. Belongs to the NSRP1 family.