May be involved in pronephros development, after specification of the pronephros. Zygotically expressed first at a low level at stage 15. Expression is markedly increased up to stage 20 after which time the level of expression remains stable. Expressed in the presumptive pronephric anlagen at stage 26. Localized to pronephros, eye, branchial arches and tail-bud in the early tadpole stage (stage 32). Belongs to the NDRG family.