Substrate-specific adapter of a DCX (DDB1-CUL4-X-box) E3 ubiquitin-protein ligase complex required for cell cycle control. The DCX(DTL) complex, also named CRL4(CDT2) complex, mediates the polyubiquitination and subsequent degradation of E2f during S phase. E2f degradation is necessary to ensure proper development. Substrates require their interaction with PCNA for their polyubiquitination: substrates interact with PCNA via their PIP-box, leading to recruit the DCX(DTL) complex. Protein modification; protein ubiquitination. Component of the DCX(DTL) E3 ubiquitin ligase complex, at least composed of Cul-4, pic/DDB1, l(2)dtl/CDT2 and Roc1a. Ubiquitously expressed during embryogenesis with no sign of tissue specificity in expression up to stage 17. Detected at all developmental stages. The extremely high level of transcription detected in the early embryo and in adults is caused by maternal message. By heat shock. Belongs to the WD repeat cdt2 family.