Plays a role in cuticle biogenesis (PubMed:23028364, PubMed:25480962). In complex with tsp-15 and the dual oxidase bli-3, promotes the generation of reactive oxygen species (ROS) and tyrosine cross-linking of collagen, thus stabilizing cuticular extracellular matrix (PubMed:23028364). Interacts with bli-3 and tsp-15. Expressed in the hypodermis, specifically in seam cells, the terminal bulb of the pharynx, the distal region of the gonadal arm, vulva, spermatheca and uterus. RNAi-mediated knockdown results in a blistered cuticle phenotype and resistance to iodide toxicity. Belongs to the DUOXA family.