Mediates both influx and efflux of nucleosides across the membrane (equilibrative transporter). It is sensitive (ES) to low concentrations of the inhibitor nitrobenzylmercaptopurine riboside (NBMPR) and is sodium-independent. It has a higher affinity for adenosine. Resistant to dipyridamole and dilazep inhibition (anticancer chemotherapeutics drugs). Identified in a complex with STOM. Predominantly localized in the basolateral membrane in polarized MDCK cells. Expressed in jejunum, liver and lung. Glycosylated. Belongs to the SLC29A/ENT transporter (TC 2.A.57) family.