ADP-ribosylates eukaryotic Rho and Rac proteins on an asparagine residue. L-asparaginyl-[protein] + NAD(+) = H(+) + N(4)-(ADP-D-ribosyl)-L-asparaginyl-[protein] + nicotinamide Monomer. To C.botulinum D and C phages exoenzyme C3, and to S.aureus EdiN.