May play a role in hematopoiesis. In the cardiovascular system, could regulate growth factors or participate in cell signaling in maintaining large vessel integrity (PubMed:23963447). Component of the elastin-associated microfibrils (By similarity). Interacts with TGFB2 (PubMed:23963447). Interacts with BMP2. Interacts with FBN1 (via N-terminal domain) and FBN2 (By similarity). Forms intermolecular disulfide bonds either with other MAGP-2 molecules or with other components of the microfibrils. Mice appear normal by several measures, are fertile, and have a normal life span, but are neutropenic. Belongs to the MFAP family.