May regulate endosome-to-lysosome trafficking of membrane cargo, including EGFR. Interacts with RHOT1/Miro-1 and RHOT2/Miro-2 (By similarity). Interacts with GABA-A receptor and O-GlcNAc transferase. Interacts with HGS. Colocalizes with MGARP at the mitochondria. Translocates from the cytoplasm to the mitochondria in a MGARP-dependent manner. Present in heart and brain (at protein level). O-glycosylated. Belongs to the milton family.