Capable of degrading extracellular matrix proteins. CASP degrades type I and IV collagen and fibronectin in the presence of calcium. Heterodimer, consisting of heavy and light chains with disulfide bonds. The heavy chain is expected to be a regulatory subunit and the light chain contains the catalytic site. The iron and 2-oxoglutarate dependent 3-hydroxylation of aspartate and asparagine is (R) stereospecific within EGF domains. Belongs to the peptidase S1 family.