Possible role in ribosomal RNA processing (By similarity). May function as a substrate receptor for CUL4-DDB1 E3 ubiquitin-protein ligase complex. Protein modification; protein ubiquitination. Interacts with DDB1 (PubMed:16949367). Interacts with ESR1 and LATS1 (PubMed:28068668). In the nucleolus, localizes predominantly in the granular component, but also detected in the fibrillar center and dense fibrillar component. Belongs to the WD repeat DCAF13/WDSOF1 family. Extended N-terminus. Extended N-terminus. Extended N-terminus. Extended N-terminus. Extended N-terminus.