Involved in the regulation of innate immune response. Acts as negative regulator of Toll-like receptor and interferon-regulatory factor (IRF) signaling pathways. Contributes to the negative regulation of transcriptional activation of NF-kappa-B target genes in response to endogenous pro-inflammatory stimuli (By similarity). Interacts with CACTIN (via N-terminal domain); the interaction occurs in a pro-inflammatory-independent manner. Nuclear localization with a speckled expression pattern in some cells. Colocalizes with CACTIN in the nucleus (By similarity). High expression found in heart muscle, liver, kidney and skin. Not detected in spleen, lung and brain.