Transcription factor that regulates respiratory growth and plays a critical role in stress adaptation during non-fermentative growth (PubMed:11353088, PubMed:20975739, PubMed:25673751). Binds to promoters of genes involved in non-fermentative metabolism, including processes such as gluconeogenesis (PCK1, FBP1 and MDH2), glyoxylate shunt (MLS1 and ICL1) and the tricarboxylic acid cycle (ACO1) (PubMed:25673751). Plays a role in maintaining mitochondrial morphology and function (PubMed:25673751). Also plays a role in tolerance to pH and osmotic stress, especially during the oxidative metabolism (PubMed:25673751). Expression is increased about 5-fold by ethanol. Impairs growth on non-fermentable carbon sources (PubMed:11353088). Results in sensitivity to a combination of low osmolarity and high temperature (PubMed:11353088). Results also in the reduced expression of genes involved in non-fermentable carbon source utilization including MLS1, FBP1, ACO1, PCK1, ICL1, MDH2, SFC1, ADY2, GDH2, FUM1, CIT1 and CIT2, when cells were shifted from glucose to ethanol (PubMed:25673751). Leads to reduced PCK1 and FBP1 enzymatic activities (PubMed:25673751). Leads to defective mitochondrial morphology with unclear structures of the inner membrane cristae when grown in ethanol (PubMed:25673751). Belongs to the MAL13 family.