Poly(ADP-ribose) synthesized after DNA damage is only present transiently and is rapidly degraded by poly(ADP-ribose) glycohydrolase (PubMed:17188026). Poly(ADP-ribose) metabolism may be required for maintenance of the normal function of neuronal cells (By similarity). [(1''->2')-ADP-alpha-D-ribose](n) + H2O = [(1''->2')-ADP-alpha-D-ribose](n-1) + ADP-D-ribose Expressed in head and tail neurons. Also detected in the central nerve cord and motor neurons. Expressed at all developmental stages. RNAi-mediated knockdown results in increased sensitivity to gamma irradiation. Belongs to the poly(ADP-ribose) glycohydrolase family. Weak activity relative to mammalian poly(ADP-ribose) glycohydrolase orthologs.