Acts as a transcriptional regulator. Together with NKX2-2, initiates transcriptional activation of NEUROD1. Involved in neurogenesis. Also required for the specification of a common precursor of the 4 pancreatic endocrine cell types (By similarity). Efficient DNA binding requires dimerization with another bHLH protein. Interacts with ATOH8. The disease is caused by variants affecting the gene represented in this entry.