Does not bind chitin in vitro. Monomer. Localizes to the peritrophic matrix ligning the midgut and on the surface of fecal pellets. Expressed in epithelial cells of the midgut. Causes an allergic reaction in human. Common symptoms of mite allergy are bronchial asthma, allergic rhinitis and conjunctivitis. Binds to IgE in 74% of 374 house dust mite allergic patients from different countries. Non-allergenic peptides derived from the C-terminal IgE epitope-containing part might be used for immunotherapy to desensitize individuals with mite allergy.