Involved in the transduction of mitogenic signals from the cell membrane to the nucleus. May also regulate the TOR signaling cascade (By similarity). ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein] ATP + L-threonyl-[protein] = ADP + H(+) + O-phospho-L-threonyl-[protein] Binds 2 Zn(2+) ions per subunit. Interacts with TH1L/NELFD. Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. RAF subfamily.