Positive regulator of protein aggregation and age-related proteotoxicity (PubMed:20723760, PubMed:28336532). Induces conformational changes in aggregation-prone proteins, driving them into compact formations preceding the formation of aggregates (PubMed:20723760, PubMed:28336532). Suppresses protein aggregation and toxicity caused by protein aggregates. Belongs to the SERF family.