Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles (By similarity). May play a role in the detoxification of reactive oxygen species produced during pathogenic bacterial infection (PubMed:22216003). glutathione + RX = a halide anion + an S-substituted glutathione + H(+) By paraquat. Induced by white light exposure (PubMed:29500338). Belongs to the GST superfamily. Sigma family.