Involved in vesicular recycling, probably as a GTPase-activating protein for Rab family protein(s). Expressed in the embryonic neural tube, brain, pectoral fins and the pronephric glomerulus (at protein level). The arginine and glutamine fingers are critical for the GTPase-activating mechanism, they pull out Rab's 'switch 2' glutamine and insert in Rab's active site. Morpholino knockdown of the protein causes pericardial edema, retracted glomerulus in an enlarged Bowman's capsule and glomerular permeability defects.