Mast cell degranulating peptide. Also permeates anionic liposomes. Has little hemolytic activity. Has an amphiphilic alpha-helix conformation. Shows broad-spectrum antimicrobial activity against the Gram-positive bacteria S.aureus ATCC 6538 (MIC=5 ug/ml), S.saprophyticus CS (MIC=5 ug/ml), S.epidermidis CS (MIC=5 ug/ml), B.subtilis CCT 2471 (MIC=40 ug/ml), and the Gram-negative bacteria E.coli CCT 1371 (MIC=20 ug/ml), E.coli ATCC 25922 (MIC=50 ug/ml), and P.aeruginosa ATCC 15442 (MIC=20 ug/ml). Blocks the lobster neuromuscular transmission. Induces the depolarization of the muscle membrane. Assumes an amphipathic alpha-helical conformation in a lipid environment. Forms a membrane channel in the prey (By similarity). Expressed by the venom gland. Belongs to the MCD family. Mastoparan subfamily.