Involved in the detoxification of xenobiotics and in the activation of ester and amide prodrugs. a carboxylic ester + H2O = a carboxylate + an alcohol + H(+) Component of a epididymal complex at least composed of soluble form of prion protein PRNP, CLU, BPI, CES5A, MANBA and GLB1. Detected in corpus and cauda epididymal fluid. Present in seminal fluid but not found to be associated with sperm (at protein level). Not expressed in other tissues. N-glycosylated. Belongs to the type-B carboxylesterase/lipase family.