The conversation between human and AI assistant.
What GUI toolkit is best for a cross-platform, desktop Python application?
It needs to work on Windows, macOS, and Linux.
All three of these toolkits are cross-platform and should work on all of those operating systems. PyQt is based on the popular Qt framework, which is known for its powerful features and elegant design. Tkinter is included with Python by default, so it's a good choice if you don't want to install any extra dependencies. wxPython is also a popular choice and has a large community of developers.