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What are the best model systems for RNA folding?
Can you explain how the P4-P6 domain of the Tetrahymena group I intron is used in RNA folding studies?
Sure, the P4-P6 domain is a self-catalytic RNA molecule that folds into a stable, compact tertiary structure. It has been used extensively as a model system for studying RNA folding and has provided valuable insights into the thermodynamic and kinetic principles of RNA folding.