The conversation between human and AI assistant.
Neuroscience: Does aging affect the first and higher order moments of neuron firing rates (like mean/variance/skew)? If so, how?
That's interesting. What about the changes in neuronal morphology that you mentioned earlier?
There is evidence to suggest that aging can lead to a reduction in dendritic complexity, alterations in spine morphology, and even loss of neurons in some regions of the brain. These changes can affect the ability of neurons to make synaptic connections, leading to changes in the balance between excitatory and inhibitory activity. This can contribute to the changes in variance and skewness that are observed with aging.