The conversation between human and AI assistant.
Can strong denaturants like guanidine hydrochloride help clear up protein aggregates from amyloid forming proteins?
That's interesting. Are there any other denaturants that are commonly used for disaggregation of protein aggregates?
Yes, another commonly used denaturant is urea. It can also disrupt protein-protein interactions and lead to disaggregation, but it may not be as effective as guanidine hydrochloride for certain types of proteins. Other denaturants, such as SDS and chaotropic agents like NaCl, have also been used in some studies.