The conversation between human and AI assistant.
What is the function of DNA ligase in DNA replication?
Can you please tell me about the function of DNA ligase in DNA replication?
Yes, I can. DNA ligase is an enzyme that joins together the Okazaki fragments on the lagging strand of DNA during replication. It creates a phosphodiester bond between the 3' hydroxyl group of the terminal nucleotide on the pre-existing DNA chain and the 5' phosphate group of the nucleotide on the new DNA strand.