It is estimated that at least 550 Shche-2 aircraft were completed before the close of production in 1946, the OKB-47 factory being closed down at the conclusion of production. After the end of the war, the aircraft remained in service for several years, with the air forces of Yugoslavia and Poland making use of the type, in addition to the aircraft being extensively utilised in transport and air ambulance duties in civilian service within the Soviet Union. In addition, the Shche-2 was operated by Aeroflot on several local airline routes within the Soviet Union for several years after the end of the war, before its replacement by the Antonov An-2.