The Catedral de Nuestra Señora de Guadalupe (English: Cathedral of Our Lady of Guadalupe or simply Ponce Cathedral) is the cathedral for the Roman Catholic Diocese of Ponce located in downtown Ponce, Puerto Rico. The cathedral lies in the middle of Ponce's town square, known as Plaza Las Delicias, located at the center of the Ponce Historic Zone. For its historic significance, the cathedral was listed on the National Register of Historic Places in 1984. It is the seat of the Bishop of Ponce, currently Rubén González Medina.