At an auction of an old local farm in 1962, Irwin noticed that many of the buyers would forever be removing the items from their historical context. Deciding that the items' true value lay in the history of their usage, Irwin purchased several items, including a horse-shoeing box that had been fished out of the Clinch River in the aftermath of the legendary Big Barren Creek Flood of 1916. Shortly thereafter, he acquired his first log structure—the General Bunch House—and moved it from its original location in the county's remote New River section. Irwin spent his weekends seeking out remote communities around the region in search of pioneer relics, which he displayed in his yard and garage. In 1969, he officially opened the Museum of Appalachia and began charging a nominal admission fee.