From its northern terminus at a junction with the Landsborough Highway near Augathella, the Mitchell Highway heads south, concurrently carrying both the A71 and Alt A2 shields and continues south through Charleville where the Warrego Highway heads east, carrying the Alt 2 shield. As the A71, the Mitchell continues south through , forming a junction with the Balonne Highway, and then south to the state border between Queensland and New South Wales (called Barringun Road) where its highway shield changes to B71.