During Damasus' early years, Constantine I rose to rule the Western Roman Empire. As emperor, he issued the Edict of Milan (313), which granted religious freedom to Christians in all parts of the Roman Empire. A crisis precipitated by the rejection of religious freedom by Licinius, Emperor of the Eastern Roman Empire, in favor of paganism resulted in a civil war in 324 that placed Constantine firmly in control of a reunited Empire. This led to the establishment of Christian religious supremacy in Constantinople and gradually led to a See in that city which sought to rival the authority of the Roman See. Damasus was most likely in his twenties at the time.