Since 2000, systematic upgrades, renovation, and renewal to MURR facilities and instrumentation in preparation for the next 20 years of licensed operation have taken place. In 2002, a building addition opened the way for expansion into cGMP scaleup of isotopes. Work began in 2006 on a addition to house laboratories, classrooms and offices to advance interdisciplinary research, education and treatment of patients. , MURR supports research of approximately 400 faculty and 150 graduate students representing more than 180 departments from more than 100 international universities and around 40 federal and industrial labs every year. A cyclotron that will supply mid-Missouri with isotopes for PET imaging and support additional research, development, and clinical trials has been installed.