Among the personal notes about members of what is now the American Chemical Society, in the November 1920 issue of the Journal of Industrial and Engineering Chemistry, is an announcement that Jacobs was leaving the federal government. He re-established his own laboratories, the National Cereal Products Laboratory, with facilities in Washington, D.C. and Manhattan. The address of the Manhattan facility is listed on his WWII draft registration as 156 Chambers Street. He remained as a consultant, however, to the Bureau of Chemistry throughout his lifetime. Jacobs also was retained throughout the rest of his life by C.F. Mueller Company to oversee the nutritional enrichment of their macaroni, noodles, and pasta products as they developed the nationally distributed brand that is still a recognized leader in the food industry.