After crossing into Evangeline Parish, LA 10 intersects LA 106 at a point known as Beaver. LA 106 heads due east toward Pine Prairie while LA 10 begins to make a long bend to the south through a sparsely populated area. later, the route resumes its eastward course. At Barber Spur, LA 10 intersects LA 13 a distance of north of Mamou. LA 13 connects to Alexandria on the north as well as Eunice and Crowley on the south. Shortly after this intersection, LA 10 passes the Mamou Municipal Airport and intersects LA 376 in Vidrine. later, LA 10 intersects and begins a concurrency with US 167 at the western edge of Ville Platte, the parish seat.