Central Luzon State University (CLSU; ) is a state university on a 658-hectare campus in Muñoz, Nueva Ecija, Philippines. It is the lead agency of the Muñoz Science Community and the seat of the Regional Research and Development Center in Central Luzon. To date, CLSU is one of the premiere institutions for agriculture in the Philippines and in Southeast Asia known for its research in aquaculture, ruminants, crops, orchard, and water management. It has also been placed between the sixth and the twenty-first spot for the most academically-excellent university in the country for various years, overwhelming most schools in Metro Manila. It has been placed in the 100 most significant schools in Asia numerous times as well.