Medical research on the effects of excessive light on the human body suggests that a variety of adverse health effects may be caused by light pollution or excessive light exposure, and some lighting design textbooks use human health as an explicit criterion for proper interior lighting. Health effects of over-illumination or improper spectral composition of light may include: increased headache incidence, worker fatigue, medically defined stress, decrease in sexual function and increase in anxiety. Likewise, animal models have been studied demonstrating unavoidable light to produce adverse effect on mood and anxiety. For those who need to be awake at night, light at night also has an acute effect on alertness and mood.