Among Dupuis' film performances are Yves, in "Being at Home with Claude" (1991; Cannes, Un Certain Regard 1992)--his first major screen role—directed by Jean Beaudin, adapted from a screenplay by Johanne Boisvert, based on the 1986 stage play by René-Daniel Dubois; and Kevin Barlow, in "Manners of Dying" (2004), the first feature film directed by Jeremy Peter Allen, adapted from his own screenplay based on the short story first published in the 1993 collection "The Facts Behind the Helsinki Roccamatios and Other Stories" by Yann Martel. His performance as Alexandre Tourneur in "Looking for Alexander (Mémoires affectives)" (2004), directed by Francis Leclerc, who co-wrote the screenplay with Marcel Beaulieu, received awards.