Following her win over Ekaterina Makarova at the China Open reigning WTA Finals champion, Radwańska qualified for the 2016 WTA Finals in Singapore. She returned to Singapore for the sixth consecutive year, the longest active streak on the tour. At the WTA Finals Radwańska was drawn into the White Group alongside Karolina Pliskova, Garbiñe Muguruza and Svetlana Kuznetsova. In her opening match she lost to Kuznetsova despite having a match point in the third set. In her second and third round robin matches Radwańska defeated Garbiñe Muguruza and Karolina Pliskova, both in straight sets. She advanced to her 4th WTA Championships semifinal, where she lost to world No. 1, Angelique Kerber. For the first time in her career Radwańska ended the season ranked world No. 3.