The cousins Salvatore "Ciaschiteddu" Greco and Salvatore "The Engineer" Greco of the Ciaculli family were also protagonists in the First Mafia War between rival clans in Palermo in the early 1960s for the control of the profitable opportunities brought about by rapid urban growth and the illicit heroin trade to North America. The conflict was sparked by a quarrel over an underweight shipment of heroin and the murder of Calcedonio Di Pisa – an ally of the Grecos – in December 1962. The Grecos suspected the brothers Salvatore and Angelo La Barbera of the attack.