Because of a redshirt year due to academic issues, Anderson was eligible as underclassman for the 1965 NFL Draft, then known as a "future" pick. In 1964, he ran for 966 yards with three touchdowns (TDs) and had 32 catches for 396 yards and four TDs; Despite being selected by the Packers, he returned for his senior season at Texas Tech in 1965 and led the Red Raiders to an 8-2 regular season and a berth in the Gator Bowl on the afternoon of New Year's Eve. As a senior, he ran for 705 yards with 10 TDs and had 60 catches for 797 yards and seven TDs.