In 1993, she starred in the television adaptation of Sidney Sheldon's novel "A Stranger in the Mirror", a on Groucho Marx and Erin Fleming, in which Loughlin plays Fleming's role. In 1997, she starred alongside Bruce Campbell in the film "In the Line of Duty: Blaze of Glory". In 2000, Loughlin co-starred opposite Treat Williams in the Fred Olen Ray-directed thriller film "Critical Mass". She also guest starred in "Suddenly Susan", "Spin City", "Seinfeld", "The Drew Carey Show", and as the superhero Black Canary in the "Birds of Prey" series in 2002.