He was returned as Member of Parliament for Liverpool in 1559. It became clear that he supported the religious settlement and Confessions of Westminster (1560), sitting on two committees of Inquiry. When an expert handler of the son of the King of Sweden visiting Westminster, he was sent in 1562 as ambassador to France as an emerging diplomatic talent; he remained in France from September 1562 with experienced envoy Sir Nicholas Throckmorton; and in 1572 Smith again went to France in the same capacity for a short time. However Smith came to dagger blows with Throckmorton over character and policy differences. He finally returned home in disgrace after suffering illness in April 1566.