Cardiomyopathy, or disease of the heart muscle, is also seen in dogs and is associated with large breeds (the exception being Cocker Spaniels, a medium-sized breed). Dilated cardiomyopathy is seen in Great Danes, Irish Wolfhounds, St. Bernards, Dobermanns, Boxers, and other large breeds. Dobermanns, in addition to heart muscle failure, are prone to ventricular arrhythmias. Boxer dogs are predisposed to a unique cardiomyopathy with clinical and histological changes analogous to human arrhythmogenic right ventricular cardiomyopathy (ARVC). The disease has been termed "Boxer cardiomyopathy" or "Boxer ARVC", and is characterized by development of ventricular tachyarrhythmias. Affected dogs are at risk of syncope and sudden cardiac death. Myocardial failure and congestive heart failure are rare manifestations of this disease.