Evidence-based studies indicate that the life span of an individual depends on two major factors, genetics and lifestyle choices. For various reasons, including biological/genetic causes, women live on average about four years longer than men. , the global average life expectancy at birth of a girl is estimated to be 74.9 years compared to 70.4 for a boy. There are significant geographical variations in human life expectancy, mostly correlated with economic development—for example life expectancy at birth in Hong Kong is 87.6 years for girls and 81.8 for boys, while in Central African Republic, it is 55.0 years for girls and 50.6 for boys. The developed world is generally aging, with the median age around 40 years. In the developing world the median age is between 15 and 20 years. While one in five Europeans is 60 years of age or older, only one in twenty Africans is 60 years of age or older. The number of centenarians (humans of age 100 years or older) in the world was estimated by the United Nations at 210,000 in 2002.