In 1984, Wilcox made her film debut in "Gimme an 'F. From 1985 to 1987, Wilcox guest starred on the television series "Hardcastle and McCormick" (1985), "You Again?" (1986), "CBS Schoolbreak Special" (1987), ' (1987), "Mr. Belvedere" (1987), and "MacGyver" (1987). In 1988, Wilcox guest starred on the television series "It's a Living" and "Hotel" before portraying Alice Johnson in the fantasy horror film '. In 1989, Wilcox had a recurring role on "Knots Landing" as Ellen and guest starred on "Something Is Out There" before reprising her role as Alice in '. The same year, Wilcox portrayed Yuta in an episode of "" called "The Vengeance Factor".