In exploring the cross-cultural circulation of the text Avner Ben-Zaken enlisted to the Picatrix's scholarship the “Yates thesis,” and argued that the text played a latent, though central, role in shaping the philosophy of Renaissance natural magic and in giving the stimulus needed to transform occultist notions into experimental science. For Renaissance thinkers unfriendly to the establishment, natural magic offered an alternative program for natural philosophy, and some turned it against Aristotelian philosophy, which they viewed as hegemonic. Moreover, these rebels presented natural magic as a scientific practice, a culture deeply grounded in non-European contexts. For Ficino and Pico, natural magic originated in the ancient Near East, brought Renaissance Europe through cross-cultural exchanges that involved Kabalistic texts and Arabic works on magic. For Agrippa, natural magic carried a new program for science, as well as new practices and new personas. For him, the magus—the new experimental naturalist—was a figure that first came to life in the ancient East. For Campanella, natural magic offered a bottom-up construction of natural philosophy that also entailed a new organization of society, in which reason and firsthand experience order both nature and society. All perceived Picatrix as a text that embodied both: a strong alternative program for the study of nature, and a strong cultural program for challenging European culture from outside. In imagining this alternative, they eventually returned their science to its historical point of origin, the East. Ficino, Agrippa, and in a sense Campanella pushed the argument further, laying a foundation for a heliocentric worldview, initiating the search for the hidden forces of nature, and casting the magician virtuoso as the godfather of natural philosophy.