Henman was unseeded at Wimbledon in 2006 for the first time in a number of years after his world ranking slipped down to number 62. At that Wimbledon, he lost in the second round to eventual champion Federer, 6–4, 6–0, 6–2, after a five-set victory over Robin Söderling of Sweden in the first round. At the US Open, Henman reached the second round where he was defeated by Roger Federer, 3–6, 4–6, 5–7. Following his failure at the US Open, Henman played two tournaments in the far east. Starting in Bangkok, Henman reached the quarter-finals where he lost to Paradorn Srichaphan 6–7, 6–4, 7–6. Henman then reached his first final since 2004 at the AIG Open in Tokyo, losing to Roger Federer, 6–3, 6–3. Although Henman was scheduled to play in both Basel & Paris at the end of the 2006 season, he lost in the second round in Basel against the rising Swiss star Stanislas Wawrinka 2–6, 7–6, 6–4. He twisted a knee; he did not retire but resorted to a less mobile game that saw Wawrinka win.