Lucy Braun also fought to conserve natural areas and set up nature reserves, particularly in Adams County. She founded the Cincinnati chapter of the Wild Flower Preservation Society in 1924, contributed to its journal "Wild Flower", and served as the journal's editor from 1928 to 1933. Her efforts to protect a 22-acre xeric limestone prairie (Lynx Prairie) led to the establishment of the Richard & Lucile Durrell Edge of Appalachia Preserve System, and ultimately to the creation of The Nature Conservancy.