On March 17, 2007, Mayo led Huntington High School to its third consecutive Class AAA basketball championship in the state of West Virginia with 103–61 rout of South Charleston. Mayo finished with a triple-double: 41 points, 10 rebounds, and 11 assists. In his final moments with a minute left in the game, Mayo threw the ball off the backboard from the free-throw line, caught it in midair, and dunked. He then threw the ball deep into the stands and held up three fingers, a reference to Huntington High's three-straight basketball state championships.