Arriving at the Brooklyn Navy Yard on 27 April 1922 from spring maneuvers in the West Indies, "Sicard" was repaired and fitted out for duty on the Asiatic Station. On 15 June, she proceeded to Newport, received torpedo equipment; and, on the 20th, got underway with her squadron for her new station, sailing via the Mediterranean Sea and the Indian Ocean. The squadron arrived at Chefoo, China, on 26 August, and joined the Asiatic Fleet, with which she operated for seven years, based at Chefoo and Tsingtao in the summer and Manila in the winter. She received periodic overhauls at the Cavite Navy Yard. She participated in fleet exercises and maneuvers, protected American interests in China, Japan, and the Philippines, and engaged in escort and patrol duty on the China Coast and on the Yangtze River during periods of unrest.