Upon marrying Hannibalianus her father made her Augusta but it was mostly an honorary title. After her husband was executed in AD 337, Constantina disappeared from the imperial record until AD 350. This is when Magnentius revolted against her brother Constantius II which caused great political upheaval. This prompted her to become directly involved in the political revolt. She exercised her political power by asking Vetranio to challenge Magnentius, thereby hoping to protect her own political interests and preserve her power.