He has run in five straight Breeders' Cup Classics, finishing third in 2005, and fourth in 2004. In 2006, he was unplaced. On November 7, 2006, Murray Johnson announced that he believed a breathing problem hindered Perfect Drift's run in the Classic. A post-race examination showed he suffered from chondritis, which limits air intake. "He couldn't get his air, basically," said Johnson. "It's caused from a virus. They breathe all right for a while and it doesn't affect the functions of the throat. But when they become tired, they just can't get the air."