His siblings are the renowned novelist late P. Vasudevan Thampi who wrote novels like "Sreekrishnaparinthu" (which became a hit Malayalam film), Advocate P. Gopalakrishnan Thampi, the former Director General of Prosecutions (Kerala),and former Chairman of Kerala Bar Council, ThulasibhaThiruvananthapuram kachi and Prasannavadanan Thampi, former Vice President of Oracle Financial Systems Software Ltd. Thampi is married to the daughter of Vaikom M P.Mani,Rajeswari and they have a daughter (Kavitha). His wife and daughter have also dabbled in the arts. He also had a son, Rajkumaran Thampi (also known as Raj Aditya) was an erstwhile associate of Priyadarshan and later directed some movies in the Telugu film industry, until his sudden death in Secundarabad in March 2009. Sreekumaran Thampi has three grand daughters Thanmaya, Varada and Thanaya. He is settled in Thiruvananthapuram. The house name is"Karimbalethu ".