Radwańska suffered her earliest ever exit at Wimbledon, when she was defeated in the second round by Czech qualifier Petra Cetkovská. At the Mercury Insurance Open, Radwańska advanced to the final and defeated rival Vera Zvonareva in straight sets. With the victory, she earned her first title since winning in Eastbourne in 2008. At the Rogers Cup in Toronto, she once again defeated Zvonareva in the third round, coming back from a 0–4 deficit in the second set. She went on to lose a three-set semifinal match against Samantha Stosur.