He often appeared with his wife Florence Arliss (née Florence Kate Montgomery Smith) (1870–1950), to whom he was married from 14 September 1899 until his death. (Leslie Arliss, who became a prolific producer-director for Gainsborough Pictures, is erroneously referred to as their son in some reference works.) Florence (or "Flo", as George called her) starred both on stage and in films, both silent and sound, with her husband and almost always played his character's spouse. However, that did not prevent Arliss from using another actress when Flo was not right for a role. Also, Flo turned down roles that George wanted her to play in some films.