Covering and with 110 rooms, the mansion is the fourth largest historic house museum in the United States. It was designed by William Kapp of the firm Smith, Hinchman & Grylls in a Tudor-revival style. The building features stonework and a plaster dining room ceiling created by Corrado Parducci. Much of the original artwork collected by the Wilsons is still found at Meadow Brook including paintings by Anthony van Dyck, Rosa Bonheur, Joshua Reynolds, John Constable and Thomas Gainsborough, as well as Tiffany glass, Stickley furniture, Meissen porcelain, and Rookwood pottery. The estate was added to the National Register of Historic Places in 1979 and National Historic Landmark in 2012.