Constantina and Constantius Gallus were then sent from Rome to Syria at Antioch to govern that portion of the Eastern Roman Empire. She would not return to Rome until her death. In AD 354, when Constantius called for Gallus, the caesar sent Constantina to her brother, with the purpose to mitigate his position in Constantius' consideration. While on her way to meet with Constantius II, she died at Caeni Gallicani in Bithynia (Asia Minor). The cause of her death was a sudden high fever of unknown cause. Her body was sent back to Rome and entombed near Via Nomentana in a mausoleum her father, Emperor Constantine I, had started building for her. This mausoleum would later become known as the church of Santa Costanza, when Constantina was venerated as saint. Her magnificent porphyry sarcophagus is on exhibit in the Vatican Museums.