Bilaterians do not contain hedgling genes, suggesting that these were lost by deletion before this branch split from the other metazoans. However, Hog domain-containing genes without a Hedge domain are present in several bilaterian lineages. They are found in Lophotrochozoa and Nematoda. Hedgehog-like genes, 2 Patched homologs and Patched-related genes exist in the worm "C. elegans". These genes have been shown to code for proteins that have roles in "C. elegans" development. Whilst Enoplea nematodes have retained a bona-fide Hedgehog, Chromadoreans have lost the archetypal Hedgehog and have instead evolved an expanded repertoire of 61 divergent semi-orthologous genes with novel N-terminal domains associated with Hog. These N-terminal domains associated with Hog in "C. elegans" were subsequently classified, initially Warthog (WRT) and Groundhog (GRD), followed by Ground-like (GRL) and Quahog (QUA). "C. elegans", along with other nematode species, have lost the GPCR Smoothened.