Ferrer then traveled to Shanghai to play in the 2010 Shanghai Rolex Masters, where he was seeded 11th. In the first round, he defeated Michaël Llodra, and then defeated Thomaz Bellucci in the second round. However, he was defeated by Robin Söderling in the third round. Due to his round of 16 showing, he moved to no. 8 in the world. Also, he moved to no. 7 in the race to the year-end championships. Ferrer then traveled to Valencia to play in the 2010 Valencia Open 500 as the hometown favorite. At the 2010 Valencia Open 500, he was seeded fourth and defeated Guillermo García-López in the first round. He then defeated qualifier Teymuraz Gabashvili for a spot in the quarterfinals. He then defeated Potito Starace to advance to the semifinals. He then defeated Robin Söderling for a spot in the final. In the final, he defeated Marcel Granollers for the title, his ninth career title. With this victory, he moved to no. 7 in the race to the year-end championships and virtually secured his spot at the 2010 ATP World Tour Finals, and also improved his ranking to world no. 7. Ferrer's final regular-season tournament was the 2010 BNP Paribas Masters, where he was seeded no. 7. Due to his seeding, he received a bye into the second round and defeated Fabio Fognini. However, he lost to Jürgen Melzer in the third round. Despite his loss, Ferrer still qualified for the Barclays ATP World Tour Finals due to the fact that Fernando Verdasco lost his third-round match, sealing Ferrer's seventh spot and his second appearance since 2007. Ferrer then traveled to London to play in the 2010 ATP World Tour Finals, where he was seeded seventh. In his first match, he lost to Federer, and in his second match he lost to Söderling. Ferrer then lost to Andy Murray to finish the 2010 ATP World Tour Finals with an 0–3 record. Ferrer finished the year with a 60–24 record, and once again in the top 10, finishing at world no. 7.