Mary of Guise ordered the people of Sherriffdom of Berwick and Lauderdale to provide 320 oxen to remove the guns from Hume in February 1558. The cannons were taken to the fort at Eyemouth. The castle was again besieged at the end of April 1570 by the Earl of Sussex during his raid into Scotland. The defenders capitulated within twelve hours, in awe of his superior numbers and the firepower of "three battery pieces and two sakers" brought from Wark Castle. Regent Morton gave money to Agnes Gray, Lady Home, in the 1570s to keep the castle garrisoned for James VI.