Chinese Filipinos are mostly the descendants of immigrants from Fujian in China after 1898, numbering around 2 million, although there are an estimated 20 percent of Filipinos who have partial Chinese ancestry, stemming from precolonial and colonial Chinese migrants. While a distinct minority, Chinese Filipinos are well-integrated into Filipino society. As of 2015, there were 220,000 to 600,000 American citizens living in the country. There are also up to 250,000 Amerasians scattered across the cities of Angeles, Manila, Clark and Olongapo.</ref> Other important non-indigenous minorities include Indians and Arabs. There are also Japanese people, which include escaped Christians (Kirishitan) who fled the persecutions of Shogun Tokugawa Ieyasu which the Spanish empire in the Philippines had offered asylum from. The descendants of mixed-race couples are known as "Tisoy".