The northern terminus of the trail is at the New York State border near Lawrenceville, Pennsylvania, meeting Crystal Hills Trail, a branch of Finger Lakes Trail crossing eastern Steuben County, New York. The southern end is on Black Valley Road at the Pennsylvania-Maryland border near Flintstone, Maryland, meeting the route of Great Eastern Trail through Green Ridge State Forest. As of 2015 there remains a unmarked gap southeast of Wellsboro, Pennsylvania. The MST is primarily on public land – state forests, game lands, and parks. MST uses private lands by permission on occasion, generally closer to the Maryland and New York borders.