Kelly, Kornienko, and Gennady Padalka launched aboard "Soyuz TMA-16M" spacecraft from the Baikonur Cosmodrome in Kazakhstan at 3:42 pm EDT on March 27, 2015. "TMA-16M" docked with the ISS at 9:36 pm EDT, and the crew joined the Expedition 43 crew of commander Terry Virts and flight engineers Anton Shkaplerov and Samantha Cristoforetti. Once aboard, the crew performed scientific experiments, including evaluations of the fluid shifts in their bodies to determine their effects on eyesight, and repeated collections of blood and urine for chemical analysis. During Expedition 43, the ISS received supplies from the SpaceX Dragon CRS-6 mission, but lost their resupply due to the failure of the Russian" Progress 59" spacecraft. Expedition 44 began on June 11, 2015, when Virts transferred command of the ISS to Padalka, and "Soyuz TMA-15M "landed in Kazakhstan at 9:44 am EDT.