One of the most common fungal diseases in dogs is ringworm, or dermatophytosis, an infection of the skin, hair, or nails. There are three fungal species that cause ringworm in dogs. About 70 percent of infections are caused by "Microsporum canis", 20 percent by "M. gypseum", and 10 percent by "Trichophyton mentagrophytes". Signs include hair loss and scaling of the skin. Treatment for localized ringworm is not always necessary as the disease is self-limiting, but the clinical course can be shortened by using topical miconazole or clotrimazole. Generalized infections, most commonly seen in immunocompromised dogs, can be treated with oral antifungal drugs such as griseofulvin or itraconazole. Infection can spread to humans.