The charity's original base is located at Nostell Priory, and has landing pads at various major hospitals around the region including Leeds General Infirmary, Hull Royal Infirmary and James Cook University Hospital in Middlesbrough. In October 2007, a second base was opened at Sheffield City Airport. The airport then closed at the end of April 2008, but a heliport facility was still provided for the use of the air ambulance and the South Yorkshire Police helicopter. In November 2010, the operational base for the Sheffield-based aircraft was moved to Bagby Airport near Thirsk.