This was the first time that a printed book had been banned by the Church, and nearly all copies were burned. Pico fled to France in 1488, where he was arrested by Philip II, Duke of Savoy, at the demand of the papal nuncios, and imprisoned at Vincennes. Through the intercession of several Italian princes – all instigated by Lorenzo de' Medici – King Charles VIII had him released, and the pope was persuaded to allow Pico to move to Florence and to live under Lorenzo's protection. But he was not cleared of the papal censures and restrictions until 1493, after the accession of Alexander VI (Rodrigo Borgia) to the papacy.