After an ankle sprain sidelined starting quarterback Sam Bradford and with backup A. J. Feeley out with a thumb injury, Clemens started on December 18 against the Cincinnati Bengals. With only 11 days to get familiar with the team and the offense, Clemens passed for 229 yards completing 25-of-36 passes. In that game, he completed a 25-yard touchdown pass to wide receiver Danario Alexander, his first NFL touchdown pass since Week 17 of the 2007 season with the Jets, but the Bengals won by a score of 20–13. Clemens started the final two games for the Rams, both losses to the Steelers and rival 49ers. He finished the 2011 season with two touchdown passes and one rushing touchdown, and was re-signed by the Rams.