The Greco Mafia family () is a historic and one of the most influential Mafia clans in Sicily and Calabria, from the late 19th century. The extended family ruled both in Ciaculli and Croceverde Giardini, two south-eastern outskirts of Palermo in the citrus growing area and also rural areas of Calabria where they controlled the olive oil market. Members of the family were important figures in the Sicilian Cosa Nostra and Calabrian 'Ndrangheta. Salvatore "Ciaschiteddu" Greco was the first ‘secretary’ of the Sicilian Mafia Commission, while Michele Greco, also known as The Pope, was one of his successors.