The major commercial importance of the Louisiana Purchase territory was the Mississippi River. New Orleans, the largest and most important city in the territory, was the most commercial city in the United States until the Civil War, with most jobs there being related to trade and shipping; there was little manufacturing. The first commercial shipment to come down the Mississippi River was of deer and bear hides in 1705. The area, always loosely defined in those early times of European claims and settlements, extended as far east as the city that is now Mobile, Alabama, begun by French settlers in 1702.