In addition to being a successful lawyer and business man, Greene founded the Grace Episcopal Church, donated the grounds for the church and rectory, and also served as the warden of it. He served as president of the board of trustees of Coe Collegiate Institute, which was later renamed Coe College. In 1872, he changed his party affiliation from Democrat to Republican. Greene was also a mason and was first Past Master of Crescent Lodge #25, Cedar Rapids (1851–52). He died in his home in Cedar Rapids, Iowa on June 23, 1880, and is buried at Oak Hill Cemetery.