Lytton made her first appearance in "EastEnders" on 18 March 2005, playing Johnny Allen's daughter Ruby Allen. In July 2006, weeks after winning the "Sexiest Female" award at the British Soap Awards, it was announced that Lytton would be leaving "EastEnders" in November 2006. On the exit of her character, Lytton had commented: "I've really enjoyed my time at EastEnders. It has been a great experience which I will never forget but I am now looking forward to trying new things and not getting typecast."