Shortly after the end of World War II a new concept of turbojet fighters would emerge. The F-84 Thunderjet which Kartveli had already developed in 1944, was going into serial production in 1946. Soon he would also add the swept-wing variant Republic F-84F Thunderstreak. A total of 10,000 of these new generation aircraft would be constructed. Then later on, he would lead the team that developed the F-105 Thunderchief. He was also heavily involved with a 1960s-era Air Force project called "Aerospaceplane", to design and build an orbital logistics vehicle a decade before NASA attempted a similar concept, known as the Space Shuttle. The radical turboramjet-powered XF-103 was another stillborn Kartveli design, a victim of the propulsion community not being able to produce a suitable engine to power the Mach 3 interceptor. Kartveli contributed significantly to the science of flight and the readiness of the US military, and was involved in designing and leading of various projects, which eventually included the A-10 Thunderbolt II.