At an early age she and her sisters, Ginevra and Ortensia, were sent to the Monastery of St. Bernardino to be educated by the community of nuns of the Franciscan Third Order Regular. When their studies were complete, her older sister, Ginevra, chose to enter the monastic community as a nun, becoming known as Sister Immacolata. In her early youth, Clarice had been noted for her piety, but, as she grew older, she became frivolous, which not even an almost-miraculous saving of her life at the age of 17 could change, nor her education at the monastery.