Van Zandt found his love for music at an early age, when he learned how to play the guitar. He watched the performances of the Beatles on "The Ed Sullivan Show" and the Rolling Stones on "Hollywood Palace" in 1964, and referred to the former as "The Big Bang of Rock n' Roll". He said that when he was 13, George Harrison was his favorite Beatle, and he later became friends with Paul McCartney and Ringo Starr. Around August 1964, he formed his first band, the Whirlwinds, which was short lived. He later formed the Mates in 1965 and joined the Shadows in May 1966. Van Zandt has cited British Invasion bands such as the Dave Clark Five, as well as Ravi Shankar and the culture of India, as early influences.