The first USAF personnel began arriving at Takhli RTAFB on 10 February 1961 when the 27th Tactical Fighter Wing (TFW) from Cannon AFB, New Mexico began deploying F-100D Super Sabres to the base to attack the Pathet Lao who were overrunning most of northwestern Laos. At Takhli, base support for the rotating Tactical Air Command (TAC) F-100 squadrons was provided by the 6011th ABS. In an organizational change, the 331st Air Base Squadron replaced the 6011th ABS at Takhli in July 1963 as the host unit at Takhli. The 331st ABS came under the command and control of 35th Tactical Group at Don Muang Royal Thai Air Force Base, near Bangkok.