Though he put up solid numbers through 114 games with the Orioles, at forty years old, Conine was clearly in the twilight of his career. Though the Philadelphia Phillies were 14.5 games back of the New York Mets in the NL East, they were in the thick of the NL's wild-card race. On August 27, 2006, they acquired Conine for cash for a player to be named later (infielder Ángel Chávez) to serve as a right-handed bat off the bench. Though Philadelphia failed to make the playoffs, Conine proved a solid addition, batting .280 with seventeen RBIs in 28 games.