The political and military balance in the region changed dramatically during the reign of Amut-piʾel II; Shamshi-Adad I had died by about 1775 BC, and his empire disintegrated, while Yasmah-Adad was removed from his throne and replaced with Zimri-Lim. Yarim-Lim I gained the upper hand and turned his kingdom into the supreme power in the Levant; Qatna was forced to respect the borders and interests of Yamhad. In Mari, Zimri-Lim, who was Yarim-Lim's protégé, married Amut-piʾel II's sister and Yasmah-Adad's widow Dam-Ḫuraṣi, and this seemed to satisfy the king of Qatna, as his relations with Mari were never hostile. In 1772 BC, the Banu-Yamina tribes revolted against Zimri-Lim, who asked Qatna for help; Amut-piʾel II sent his troops to Dūr-Yahdun-Lim (probably modern Deir ez-Zor) to support Mari, but when he asked for Mariote military support at a later time, Zimri-Lim hesitated as Yarim-Lim I was expressly against such a dispatch. When Qatna tried to establish an alliance with Eshnunna, Mari, which was at war with Eshnunna, arrested the messengers on the pretext that Zimri-Lim feared for their safety; in reality, the king of Mari was probably acting on behalf of Yamhad to prevent Qatna from establishing such an alliance.