There are still stringent regulations in place for the development of standards for nanosensors to be used in the medical industry, due to insufficient knowledge of the adverse effects of nanosensors as well as potential cytotoxic effects of nanosensors. Additionally, there can be a high cost of raw materials such as silicon, nanowires, and carbon nanotubes, which prevent commercialization and manufacturing of nanosensors requiring scale-up for implementation. To mitigate the drawback of cost, researchers are looking into manufacturing nanosensors made of more cost-effective materials. There is also a high degree of precision needed to reproducibly manufacture nanosensors, due to their small size and sensitivity to different synthesis techniques, which creates additional technical challenges to be overcome.