On May 6, 2013, Arencibia hit a two-run home run to give the Blue Jays an 8–7 lead against the Tampa Bay Rays, in a game where they had been down 7–0 after the third inning. The comeback victory was the largest by the Blue Jays since a 12-11 win in 2007, also against Tampa Bay. It was to be a rare 2013 highlight for Arencibia, who was a consistent target of criticism from both the fans and the press for his poor statistical performance that year.