I-490 now becomes part of the Inner Loop as it passes just south of the city center and heads toward the Genesee River. I-490 crosses both the river and NY 383 by way of the Frederick Douglass–Susan B. Anthony Memorial Bridge and connects to NY 15 before leaving the Inner Loop and turning south and east to follow the former pathway of the Erie Canal and the Rochester Subway through the east side of the city. Along this stretch, I-490 connects to NY 31 (now part of Monroe Avenue) and passes north of Cobbs Hill Reservoir and the surrounding Cobbs Hill Park.