The Minnesota Department of Health is the primary state health agency responsible for public policy and regulation. Medical care in the state is provided by a comprehensive network of hospitals and clinics operated by a number of large providers including Allina Hospitals & Clinics, CentraCare Health System, Essentia Health, HealthPartners, M Health Fairview and the Mayo Clinic Health System. There are two teaching hospitals and medical schools in Minnesota. The University of Minnesota Medical School is a high-rated teaching institution that has made a number of breakthroughs in treatment, and its research activities contribute significantly to the state's growing biotechnology industry. The Mayo Clinic, a world-renowned hospital based in Rochester, was founded by William Worrall Mayo, an immigrant from England.