Shvedova has made three Grand Slam singles quarterfinals: at the 2010, the 2012 French Open and the 2016 Wimbledon Championships. She has won two Grand Slam women's doubles titles, the 2010 Wimbledon Championships and the 2010 US Open, partnering American player Vania King in both. Shvedova is also one of only seven players to record a golden set in the Open Era. She achieved this feat 2012 at Wimbledon in her match against Sara Errani, the only time a golden set was recorded in a Grand Slam championship.