The line, along with the Main Line through Paterson, served as a segment of the Erie Railroad's long-distance flagship trains to points west such as Binghamton, New York State's Southern Tier, Buffalo, and Chicago, on daily routes such as the day route, the "Erie Limited". Additional through trains to Chicago were the "Pacific Express," and its east-bound counterpart, the "Atlantic Express." The "Lake Cities" and the "Atlantic Express"/"Pacific Express" were night-time departures. The "Erie Limited" was discontinued in 1963. Other routes west were eliminated throughout the course of the 1960s. The last train west of Port Jervis, #21/#22, a daily train to Binghamton, had its final run on November 27, 1966.