The second Key debuted in "Justice League of America" #41 (December 1965). The unidentified man known as the Key develops mind-expanding "psycho-chemicals" that activate his 10 senses. Assisted by henchmen known as "Key-Men" and a "key blaster" gun, the Key has several failed run-ins with the Justice League of America (JLA). The Key first drugs the Leaguers, which not only causes them to disband the Justice League, but also physically blinds them to the existence of the Key and his Key-Men. The Key fails to take into account Hawkman's sidekick, Hawkgirl, who frees him from the drug's effects. They free the other Leaguers, and the Key is imprisoned.