With his newfound intellect, Doc Green came to the conclusion that the world was in danger by Gamma Mutates and thus needed to be depowered. He developed a serum made from Adamantium nanobites that absorbed gamma energy. He used these to depower Red Leader, Red She-Hulk, Red Hulk, Skaar, Gamma Corps, and A-Bomb, but decided to 'spare' She-Hulk as he concluded that she was the one gamma mutation whose life had been legitimately improved by her mutation. At the close of the storyline, Doc Green discovered that he was beginning to disappear as the result of the Extremis serum wearing off. He ultimately allowed himself to fade away, returning to his normal Hulk form, as he feared that remaining at his current intellectual level would lead to him becoming the Maestro.