Anderson began his NFL career in 1966 as #44 for the world-champion Packers. Fellow All-American Jim Grabowski, a fullback from Illinois, was the Packers' first pick in the 1966 NFL Draft, and ninth overall. The well-paid pair were the projected successors of Paul Hornung and Jim Taylor, future hall of famers in their final season with Green Bay. The two rookies were on the College All-Star team that lost to the defending NFL champion Packers 38–0 on August 5 at Soldier Field in Chicago. They joined the Packers' training camp after the game, and were tabbed the "Gold Dust Twins."