He won the French Open 2003 junior doubles title. Representing Israel in the Davis Cup, highlights include an upset win in 2007 over World No. 7 Fernando González and being a key factor in Israel's semifinal run in 2009. In 2008 he beat World No. 5 David Ferrer in straight sets, and in 2010 he beat World No. 7 Andy Roddick in straight sets. Sela reached the fourth round of the 2009 Wimbledon Championships and has finished runner-up in two ATP tournaments in Beijing and Atlanta. In 2015, he won his 24th Challenger event of his career, moving him into sole possession of second place on the all-time list of Challenger title wins.