The "universal genius" Leonardo da Vinci was to further perfect the aspects of pictorial art (lighting, linear and atmospheric perspective, anatomy, foreshortening and characterisation) that had preoccupied artists of the Early Renaissance, in a lifetime of studying and meticulously recording his observations of the natural world. His adoption of oil paint as his primary media meant that he could depict light and its effects on the landscape and objects more naturally and with greater dramatic effect than had ever been done before, as demonstrated in the "Mona Lisa" (1503–1506). His dissection of cadavers carried forward the understanding of skeletal and muscular anatomy, as seen in the unfinished "Saint Jerome in the Wilderness" (c. 1480). His depiction of human emotion in "The Last Supper", completed 1495–1498, set the benchmark for religious painting.