Mayo was selected as Mr. Basketball of Ohio for the second consecutive season, in addition to being named Associated Press Division III Player of the Year for the second consecutive season. He averaged nearly 29 points, nine rebounds, and six assists per game. He also led his team to three consecutive AP poll titles and garnered much attention from the media, appearing in the pages of "Sports Illustrated" among other publications. Much like another high school star from Ohio (St. Vincent–St. Mary High School), LeBron James, Mayo drew large enough crowds to force his team into seeking larger venues to support the growing crowds, and often attracted National Basketball Association stars such as James and Carmelo Anthony to watch his games playing for the D-1 Greyhounds.