Mario created few operatic parts, the most notable being that of Ernesto in Donizetti's "Don Pasquale" (1843). However, he sang in the première of Rossini's "Stabat Mater", and Verdi wrote a new cabaletta for him to sing in the main tenor aria in "I due Foscari" for a production in Paris. In established roles, Mario's greatest performances were as the title character in Rossini's "Otello", Gennaro in "Lucrezia Borgia", Almaviva in "Il Barbiere di Siviglia", Fernando in "La favorite", the Duke in "Rigoletto", Alfredo in "La traviata", Manrico in "Il trovatore", Lionel in "Martha" and many others. The Royal Opera House, Covent Garden in London and the Théâtre Italien in Paris were the scenes of most of his stage triumphs. He sang in London from 1847 until 1867, and again during 1871.