Boyce was back in the starting line-up at the beginning of the 2010–11 season, but suffered an injury against Bolton Wanderers in October 2010. He was initially expected to recover in two weeks, but was sidelined for considerably longer after aggravating the injury in training. He returned to the side on 8 January 2011 in the 3–2 FA Cup victory against Hull City. He appeared 22 times in the league, and started in the final game of the season against Stoke City, making a goal line clearance in the first half to keep the score level. Wigan went on to win the game 1–0, securing Premier League survival on the last day of the season for a second time. Boyce was the only Wigan player to play in both the Stoke game and the match against Sheffield United in 2007.