George Sears Greene (May 6, 1801 – January 28, 1899) was a civil engineer and a Union general during the American Civil War. He was part of the Greene family of Rhode Island, which had a record of distinguished military service to the United States. He first served in the Army from 1823 to 1836 after graduating second from his class at West Point. As a civilian, he was one of the founders of the American Society of Civil Engineers and Architects and was responsible for numerous railroads and aqueduct construction projects in the northeastern United States.