Approximately north of it crosses the Darling River before heading into Bourke where it forms junctions with the Kamilaroi Highway heading east and the Kidman Way heading south. From this point the highway generally heads southeast through Nyngan where it forms a junction with the Barrier Highway. From this point until its southern terminus, the Mitchell carries the National Highway A32 shield. At the Mitchell forms a junction with the Oxley Highway, before passing through and then heads generally east to the major rural centre of Dubbo where it meets with the Newell Highway and connects to the Golden Highway before crossing the Macquarie River and heading south towards , again crossing the Macquarie River. At the Mitchell generally starts to head east towards , where an alternative route diverts many heavy vehicles away from the city centre. The portion of the Mitchell Highway that passes through Orange city centre is known as Summer Street. The Mitchell Highway's southeastern terminus is at a roundabout in Bathurst, at the junction of the Mid-Western Highway to and the Great Western Highway to Sydney via the Blue Mountains.