Duncan Fegredo's first major American work was on the 1991 "Kid Eternity" miniseries with Grant Morrison. A 1992 cover for "Doom Patrol" similarly fell in Vertigo territory "pre"-Vertigo, while Fegredo's first "true" Vertigo work was also on the joint-first new series released by the imprint: Peter Milligan's "Enigma". Immediately after the end of the 8-issue series, Fegredo took over as cover artist on Milligan's long-running "Shade, the Changing Man" (issues #42–50), collaborated with Milligan on 1995's one-shot "Face" (Jan) and then returned to cover duties on "Shade", producing all but one of the remaining pieces of art. He produced pencils and inks for the miniseries "Millennium Fever" (1995) and (with Milligan) for "Girl" (1996). Between 1997 and 2002, he contributed artwork on fill-in issues (or to jam issues) of "Crusades", "The Dreaming", "Flinch", "House of Secrets", "The Sandman Presents: Everything You Always Wanted to Know About Dreams...", "Totems", "Weird War Tales" and "Weird Western Tales". In addition, his cover work graced the 1999 miniseries "Sandman Presents: Love Street", six issues of "The Books of Magick: Life During Wartime" and the first fifteen issues of Mike Carey's "Lucifer".