Pressel finished sixth in the first stage of the LPGA Qualifying Tournament in September 2005 and advanced to the final stage in December. She turned professional in November, after appealing to the LPGA to become a member as a 17-year-old. LPGA rules state that members must be 18 years old. At the five-round Final Qualifying Tournament in Daytona Beach, she finished tied for sixth to earn her tour card for 2006. She played part-time on the tour until her high school graduation in May 2006.