At Padua, Luzzatto had a much larger scope for his literary activity, as he was able to devote all his time to literary work. Besides, while explaining certain parts of the Bible to his pupils he wrote down all his observations. Luzzatto was the first Jewish scholar to turn his attention to Syriac, considering a knowledge of this language of significant importance for the understanding of the Targum. His letter published in Kirchheim's "Karme Shomeron" shows his thorough acquaintance with Samaritan.