Mercy Health System, based in St. Louis, is a Level 1 Trauma Center, and runs a pediatric cancer center. Mercy Springfield is one of only six St. Jude Children's Research Hospital affiliates in the country, located inside the Jane Pitt Pediatric Cancer Center. Said center is named for Jane Pitt, mother of actor and Springfield native, Brad Pitt, who helped to fund the center with help from his brother, businessman Douglas Pitt, sister Julie, and then partner, actress Angelina Jolie. Both Cox and Mercy maintain Ronald McDonald House Charities and houses for families of those who have children undergoing medical treatment.