He also appeared regularly on "The Larry Sanders Show" as Hank Kingsley's personal assistant Brian, and made numerous guest appearances on other television series, including "Politically Incorrect", "The Late Show", "Late Night with Conan O'Brien", and "Train 48". Thompson hosted a reality television program in Canada called "My Fabulous Gay Wedding". Thompson defended Mordecai Richler's novel "Cocksure" in "Canada Reads 2006". He has continued to tour, and act in numerous movies and on TV. He joined the other Kids in the Hall to tour as recently as 2014, guest-starred in two episodes of "Reno 911!", and performed in the project "Death Comes to Town" (2010) with fellow KITH members Dave Foley, Bruce McCulloch, Mark McKinney, and Kevin McDonald. He had a recurring role in the NBC series "Hannibal", playing Jimmy Price, an FBI crime-scene investigator specializing in latent fingerprints.