In December 1663 Magnol received the honorary title "brevet de médecine royal" through mediation of Antoine Vallot, an influential physician of the king. No means of his financial stability are mentioned (Magnol did not have a wealthy family to support him) but it is suggested that he was practicing medicine and had an income out of that. From 1659 on he devoted much of his time to the study of botany and made several trips through the Languedoc, the Provence, to the Alps and to the Pyrenees. In 1664 there was a vacancy for 'Demonstrator of plants' in Montpellier and Magnol was proposed for the position. He was denied the appointment because of religious discrimination. This happened again in 1667 when he was the leading candidate for the chair of Professor of medicine.