Her worn-out and poor condition contributed to her being wrecked when in June 1809 she grounded on an uncharted shoal in the mouth of the River Plate, whilst seeking shelter with the rest of her squadron from a storm. All hands and most of the ship's stores were saved, but the condition of the ship's timbers made it impossible to free the ship; her captain was cleared of responsibility for the ship's loss thanks to documents detailing her defects. In 1993, the wreck of "Agamemnon" was located, and several artefacts have since been recovered, including one of her cannons.