Meusel had a breakout year in 1925. He led the American League in home runs (33), runs batted in (134), games played (156) and extra base hits (79). Despite this, he finished merely tied for 18th position overall for the AL's Most Valuable Player award, far behind winner (and former Yankee) Roger Peckinpaugh of the Washington Senators. The Yankees had their worst season of the decade, finishing seventh in the league with a 69–85 record. In the following 1926 season, Meusel only played in 108 games, batting .315 with 12 home runs and 81 runs batted in. In the 1926 World Series against the St. Louis Cardinals, Meusel dropped a key fly ball with one out and the bases loaded in the fourth inning of Game 7, allowing the Cardinals to tie the game 1–1; the next batter singled to drive in two more runs. Meusel had chance to redeem himself later in the game, but made infield outs in both the fifth and seventh innings, each time with two men on base. In the bottom of the ninth inning, with New York trailing 3–2, Cardinals starting pitcher Grover Cleveland Alexander retired the first two batters and then walked Ruth. Meusel was up to bat when Ruth tried to steal second base, and catcher Bob O'Farrell threw him out, ending both the game and the Series; Meusel only hit .238.