In general, more human activity up stream (i.e. the larger the stream/river) the greater the potential for contamination from sewage effluent, surface runoff, or industrial pollutants. Groundwater pollution may occur from human activity (e.g. on-site sanitation systems or mining) or might be naturally occurring (e.g. from arsenic in some regions of India and Bangladesh). Water collected as far upstream as possible above all known or anticipated risks of pollution poses the lowest risk of contamination and is best suited to portable treatment methods.