"Metroid Prime Hunters" features a multiplayer mode that supports up to four players and includes voice chat capability. In it, the player is able to control Samus or one of six other bounty hunters featured in the single-player mode. Each bounty hunter has a unique alternative form, such as Samus's Morph Ball, and a special weapon. The game host can set options for point and time limits, and restrict the use of radar. Computer-controlled players of varying skill levels can be added to games if the minimum of four players is not met.