The route continues northeast on Joliet Road through McCook and Lyons, then jogs north briefly onto Harlem Avenue to Ogden Avenue in Berwyn, where it meets US 34. From Berwyn, Route 66 continues northeast on Ogden Avenue past the Berwyn Route 66 Museum, passing through Cicero before entering Chicago on a diagonal and progressing through the Greater Lawndale area, where it divides North Lawndale from South Lawndale before moving through Douglass Park, the Tri-Taylor Historic District and the Illinois Medical District on the Near West Side.