In 1286, a Roman nobleman named Egidio Lufredi donated several houses in the area of Campo Marzio to the Order. The friars requested authorization to construct a church and a monastery on this land; Pope Honorius IV, however, only authorized the construction of the monastery because a new church would be too close to the Church of St. Tryphon in Posterula, at the corner of the current Via dei Portoghesi and Via della Scrofa. Instead, the Pope entrusted the already existing church, which preserved the relics of martyrs Saints Tryphon, Respicius, and Nympha, to the Augustinians.