Despite his apparent rejection of eugenics, Pearl maintained relatively good relations with key eugenicists and expressed classist views. He made statements which have been interpreted as being anti-Semitic. From 1927-1932, Pearl and his colleague Alan Meyer were important figures of one of the first birth control clinics in the United States called Baltimore's Bureau for Contraceptive Advice. Pearl was a supporter of birth control, but had a more conservative and scientific approach when compared to the ideologies of Margaret Sanger. The clinic performed a eugenic medicine study that looked at how the distribution of birth control information that was provided by a clinic affected society.