On 4 January 1762, Britain declared war on Spain in the Seven Years' War, and began preparing for an expedition against Spanish possessions in the Caribbean. The 56th was assigned as part of the expeditionary force, and sailed from Portsmouth on 5 March, arriving off Havana on 6 June and landing the following day. The regiment numbered a total of 933 officers and men, and was brigaded with four companies of the 1st Foot and a battalion of the 60th Foot.