One major meta-analysis published in 2011, including previous cohort and case-control studies, concluded that multivitamin use was not significantly associated with the risk of breast cancer. It noted that one Swedish cohort study has indicated such an effect, but with all studies taken together, the association was not statistically significant. A 2012 meta-analysis of ten randomized, placebo-controlled trials published in the "Journal of Alzheimer's Disease" found that a daily multivitamin may improve immediate recall memory, but did not affect any other measure of cognitive function.