The 2020-21 season began later than usual on Saturday 19th September. Due to the Borough of Scarborough declaring a higher than average rate of positive COVID-19 cases in September and October, Boro moved their first home league games of the season to the respective away grounds to avoid the financially challenging situation of playing behind closed doors. An exception to this was Boro's early FA Cup exit at the 1st Qualifying Round stage on Tuesday 22 September, where an empty Flamingoland Stadium saw Ashton United claim a 2-0 victory. Boro's league season started solidly, with three wins, two draws, and two defeats from the opening seven matches. On 17 October, Boro welcomed fans to a home game for the first time since the March national lockdown, with a sold out capped attendance of 600 witnessing a 1-1 draw with Nantwich Town. In February 2021, it was confirmed that for the second consecutive season the league would not be completed due to the ongoing pandemic.