"La Tortura" was released as the lead single from "Fijación Oral, Vol. 1" on 12 April 2005. It features Spanish singer-songwriter Alejandro Sanz, and was praised for its production and reggaeton influence. "La Tortura" was the only single from the album to chart on the US "Billboard" Hot 100 (peaking at number twenty-three), and reached number one on the "Billboard" Hot Latin Songs, Tropical Songs, and Latin Pop Airplay charts. The song set a record for the most weeks at number one, and additionally became the best-performing Latin single of the year. The track was eventually certified Gold by the Recording Industry Association of America (RIAA) for selling over 500,000 copies and certified platinum for selling over 1 million mastertones . Internationally, "La Tortura" topped the Hungarian Rádiós Top 40 and the Spanish and Venezuelan singles charts. Its music video was directed by Michael Haussman, depicting a fictionally-romantic Shakira and Sanz.