The Atlantic Coast, St. Johns & Indian River Railroad in 1885 linked Titusville with Enterprise, from which ran a spur line to the Jacksonville, Tampa and Key West Railway at Enterprise Junction in present-day DeBary. But in 1888, Florida experienced an epidemic of yellow fever. The population of Enterprise dwindled, and DeLand became the county seat. The freezes of 1894 and 1895 wiped out the citrus industry in much of the state, including the deBary groves. Enterprise voted to de-incorporate in 1895. Its distinctive midden, once featured on the city seal, would disappear, as well as the shells used to pave streets and sidewalks.