In the main chapel, or chancel, Filippo Lippi and Fra Diamante painted the "Stories of St. Stephen and St. John the Baptist". On the lower north wall are depicted the "Obsequies of St. Stephen", in which Lippi portrayed Pope Pius II, set in a Palaeo-Christian basilica, as an imposing figure in scarlet costume. On the right is the artist's self-portrait. On the opposite wall is "Herod's Banquet", showing a large hall in which Salome is performing her ballet, and the handing over of the head of John the Baptist to Herodias. The altar is by Ferdinando Tacca (1653).