Research supporting differences among different treatments for specific disorders is now reflected in the latest EST guidelines. ESTs are developed from multiple control trial tests to evaluate which therapies yield the best results for specific disorders. These disorders include, but are not limited to, major depressive disorder, anxiety disorder, panic disorder, and OCD. According to the Ethics Code of the American Psychological Association (APA), psychologists and therapists have an obligation to avoid harming their clients in any way. ESTs are a major component in this movement. By using specific therapies clinically proven to improve certain disorders, therapists are avoiding further damage to their patients. However, supporting the idea of ESTs inevitably implies that some therapies are in fact more efficacious than others for particular disorders.