Lenore Romney was a popular First Lady of Michigan and was a frequent speaker at events and before civic groups. She was involved with many charitable, volunteer, and cultural organizations, including high positions with the Muscular Dystrophy Association, YWCA, and American Field Services, and also was active in The Church of Jesus Christ of Latter-day Saints of which she was a lifelong member. She was an asset to her husband's 1968 presidential campaign. Although a traditionalist, she was an advocate for the greater involvement of women in business and politics.