There are many books and journal articles devoted entirely or in part to compound management. It has become a critical technological component for high-throughput screening and chemical genomics. There are great challenges to be faced in the necessity of compound management, which are being surmounted by concerted efforts in the public and private domain. In 2008, authors at the National Institutes of Health's Chemical Genomics Center have released a paper showing the necessity of a highly automated, reliable and parallel compound management platform, in order to serve over 200,000 different compounds.