The stretch from Cayuga to Chenoa was added to the National Register of Historic Places on July 23, 2007. This section of US 66 was commissioned in 1926. The road segment travels from the northeast to the southwest and begins in the southeast corner of Odell Township in Livingston County and ends in the northwest corner of Chenoa Township in McLean County. US 66 passes through Odell, Esmen, Pontiac, Eppards Point, and Pike Townships, on its stretch from Cayuga to Chenoa. The road is paralleled on its east by the Union Pacific Railroad tracks and on its west by I-55. Portions of the northbound and southbound lanes still carry traffic; in spots where one of the sections is still in use the other section is abandoned but still extant.