While using Cerebra and talking to Beast during the "" storyline, Charles detects a new mutant so powerful it fries Cerebra's system. He asks Cyclops to send out a team to find out about the mutant. Once the team has come back empty handed, he argues with Scott for not telling him about the team he deployed to find former Acolytes. Scott tells him outright that he doesn't need him to run the X-Men anymore. This upsets Charles and annoys him later on when he overhears Cyclops briefing X-Factor on the situation. He also approaches the New X-Men in an attempt to help them figure out a non-violent way to help against the Purifiers, but is quickly rebuked by Surge, who questions where he was when they were getting attacked the first time, and that they didn't need to learn from him. Charles questions Cyclops' decision to send X-Force to hunt down his own son, Cable, in front of the students. Cyclops then tells Xavier that he is a distraction that will keep getting in the way and that he must leave the mansion. Xavier is contacted by Cable, who lost the mutant newborn to the traitorous actions of Bishop, who in turn lost the child to the Marauders, and tells him that he is the only one who can help Cable save the future. In the final fight, Xavier is accidentally shot in the head by Bishop. Immediately afterward Xavier's body disappears and Cyclops declares that there are no more X-Men.