Selected as an astronaut candidate by NASA in July 2000, Boe reported to the Johnson Space Center in August 2000. Following the completion of two years of training and evaluation, he was assigned technical duties in the Astronaut Office Advanced Vehicles Branch and Station Operations Branch. His current technical assignment involves work with displays and controls for future space vehicles. He made his first trip to space as pilot of during STS-126 on November 14, 2008. Boe flew his second space flight as pilot on STS-133, the final scheduled flight of the Space Shuttle "Discovery" and the third-to-last flight of the Space Shuttle program.