Mayagüez later became the cultural and political center of the western part of Puerto Rico. Due to its physical isolation from the rest of the island (the city was founded on a coastal valley surrounded by mountains) and its need for self-sufficiency from Puerto Rico's main government (which, some of its current inhabitants claim, lasts to this day) Mayagüez developed a peculiar local culture and a strong sense of regional pride that tends to distinguish its inhabitants from the rest of Puerto Rico's. Some historians claim that this strong, fiercely independent culture was responsible for breeding not only liberal thinkers such as Eugenio María de Hostos, but also radical ones such as Dr. Ramón Emeterio Betances, the father of the Puerto Rican independence movement and first medical director of Mayagüez's Municipal Hospital (currently known as "Hospital San Antonio"), Segundo Ruiz Belvis, the father of the Puerto Rican Abolitionism movement and a former city administrator, and José de Diego, first president of the Puerto Rico House of Representatives and founder of the local College of Agriculture and Mechanic Arts. The Grito de Lares, Puerto Rico's first major pro-independence revolt, was planned at a farm in the outskirts of town. The September 23, 1868 revolution was remotely organized by Dr. Betances who, twelve years earlier, had literally saved the town from extinction by a cholera epidemic that killed over 30,000 people in the island and decimated the town's population. Today, the local medical center and the main thoroughfare that crosses the city from north to south are named after Dr. Betances.