Sime achieved his greatest collegiate victory as a 19-year-old sophomore at the Drake Relays in April 1956, where he was named the meet's outstanding performer after setting a meet record in the 100-yard dash in 9.4 seconds; he handed Bobby Morrow of Abilene Christian his first loss in over thirty races in the 100, and was inducted into the Drake Relays Athlete Hall of Fame in 1959. Sime was named the ACC Athlete of the Year in 1956 for his accomplishments in track and baseball. Prior to the Olympic trials, he and Morrow appeared on the cover of "Sports Illustrated" in 1956.