Giraldo said on "Late Night with Conan O'Brien" on July 7, 2005, that he had quit drinking alcohol. His series "Friday Night Stand-Up with Greg Giraldo" began on Comedy Central in late 2005 and ran until 2006. His CD "Good Day to Cross a River" was released in 2006 by Comedy Central Records. Giraldo was featured (along with Dane Cook and Sean Rouse) in "Dave Attell's Insomniac Tour", released April 2006. This 98-minute film is thought by many of his fans to be one of his best performances—showing him on stage at work and also behind the scenes, with a glimpse of life on the road as a comedian.