US 25/US 341/SR 27 continues north along Newcastle Street as a four-lane highway with center turn lane out of the city of Brunswick. The highway has a partial interchange with Norwich Street and its name changes to Norwich Street Extended. The highways cross over the paralleling rail line and have a partial interchange with Ross Road and another road that parallels the railroad. In the unincorporated community of Dock Junction, the highways intersect SR 303, which heads east as Community Road and west as Blythe Island Highway. Immediately to the south of the intersection is an acute intersection with SR 303 Conn., which serves as a cutoff between US 25/US 341/SR 27 and SR 303. The highways continue as New Jesup Highway across Yellow Bluff Creek and expand to a six-lane divided highway ahead of their partial cloverleaf interchange with I-95. US 25/US 341/SR 27 become a four-lane highway with center turn lane again, intersect CSX's Brunswick Subdivision at grade, and intersect SR 32 and SR 99 in the hamlet of Sterling. SR 99 heads east as Grants Ferry Road; SR 32 and SR 99 head west as Harrell Highway.