Scientists of Russian Academy of Sciences are searching for methods of reducing the risk of radiation-induced cancer in preparation for the mission to Mars. They consider as one of the options a life support system generating drinking water with low content of deuterium (a stable isotope of hydrogen) to be consumed by the crew members. Preliminary investigations have shown that deuterium-depleted water features certain anti-cancer effects. Hence, deuterium-free drinking water is considered to have the potential of lowering the risk of cancer caused by extreme radiation exposure of the Martian crew.