SR 20 continues through southern Albemarle County as Scottsville Road. The state highway heads through Glendower, where the highway passes close to the historical presidential retreat Pine Knot and Christ Church Glendower. North of Keene, SR 20 crosses the Hardware River as the watercourse and the highway passes through a gap between Green Mountain and Carters Mountain, which are part of the Southwest Mountains. The state highway follows the west side of the latter mountain to the community of Mill Creek, where the highway expands to a four-lane divided highway at its intersection with SR 53 (Thomas Jefferson Parkway). SR 53 provides access to Thomas Jefferson and James Monroe's respective estates of Monticello and Ash Lawn–Highland. SR 20 passes the entrance to Piedmont Virginia Community College just south of its partial cloverleaf interchange with Interstate 64.