Born in Kingsthorpe, Northampton, Hickson was a daughter of Edith Mary (née Bogle) and Alfred Harold Hickson, a shoe manufacturer. Boarding at Oldfield School at Swanage in Dorset she went on to train at RADA in London. Making her stage debut in 1927, she worked for several years throughout the United Kingdom and achieved success playing comedic, often eccentric characters in London's West End, including the role of the cockney maid Ida in the original production of "See How They Run", at the Q Theatre in 1944, and then at the Comedy Theatre in January 1945.