Trimble's first marriage, to Heather McComb in August 1968, ended in divorce in 1976. There were no children from his first marriage. Trimble married a former student, Daphne Elizabeth (née Orr), in August 1978. They have two sons and two daughters (Richard, Victoria, Nicholas, and Sarah). Lady Trimble served as a member of the Equality Commission for Northern Ireland, and later the Northern Ireland Human Rights Commission, before standing unsuccessfully in the UK parliamentary election of May 2010 for the Ulster Conservatives and Unionists.