At national level, Newton Mearns forms part of the Eastwood constituency (since renamed to its original name of "East Renfrewshire"), and historically, it was one of Scotland's safest Conservative seats in the Parliament of the United Kingdom. From the 1997 general election, when Barrhead and Neilston were added to the constituency, until 2015 the seat was held by Labour. In the 2015 election it was gained represented by the SNP's Kirsten Oswald, but in 2017 general election it was gained by the Conservative Paul Masterton. Oswald regained the seat in the 2019 general election.