The wing was redesignated the 456th Strategic Aerospace Wing and was activated at Beale Air Force Base, California in February 1963. It flew Boeing B-52 Stratofortress bombers and Boeing KC-135 Stratotanker air refueling aircraft, and also commanded a HGM-25A Titan I squadron until 1965. Although it operated no intercontinental ballistic missiles after then, it was not until July 1972 that the wing was redesignated the 456th Bombardment Wing. The wing was inactivated in September 1975 and its personnel, equipment, and mission transferred to the 17th Bombardment Wing, which moved to Beale on paper from Wright-Patterson Air Force Base, Ohio.