After receiving his degree, Partridge became Queensland Travelling Fellow at Balliol College, Oxford, where he worked on both an MA on eighteenth-century English romantic poetry, and a B.Litt in comparative literature. He subsequently taught in a grammar school in Lancashire for a brief interval, then in the two years beginning September 1925, took lecturing positions at the Universities of Manchester and London. From 1923, he "found a second home", occupying the same desk (K1) in the British Museum Library (as it was then known) for the next fifty years. In 1925 he married Agnes Dora Vye-Parminter, who in 1933 bore a daughter, Rosemary Ethel Honeywood Mann. In 1927 he founded the Scholartis Press, which he managed until it closed in 1931.