Poundstone worked as a political correspondent for "The Tonight Show" during the 1992 US Presidential campaign and did field pieces for "The Rosie O'Donnell Show" in 1996. In 1993, Poundstone won a second CableACE Award for "Best Program Interviewer" for her HBO series "The Paula Poundstone Show." She was then featured in her own variety show, "The Paula Poundstone Show," on ABC (which lasted two episodes). She also appeared on "Hollywood Squares" and was a regular panelist for the remake of "To Tell the Truth". Poundstone had a recurring role in Cybill Shepherd's TV series "Cybill" (1997).