Bautista competed for the Suzuki team in his first two years after moving into the MotoGP class in . He moved to the Honda-equipped Gresini Racing team starting in the season, and continued with the team using Aprilia machinery when the factory returned to MotoGP racing for the season. Bautista rode a Ducati with the Aspar (then Ángel Nieto Team) MotoGP Team in 2017 and 2018, before moving to the Superbike World Championship for 2019 also on a Ducati, this time with the Aruba.it Ducati WorldSBK Team.