The Japanese attack on Pearl Harbor in December 1941 and the subsequent United States declaration of war upon Italy rendered Segrè an enemy alien and cut him off from communication with his parents. Physicists began leaving the Radiation Laboratory to do war work, and Raymond T. Birge asked him to teach classes to the remaining students. This provided a useful supplement to Segrè's income, and he established important friendships and professional associations with some of these students, who included Owen Chamberlain and Clyde Wiegand.