Joseph and Speedwagon travel to Rome, where they meet Caesar Zeppeli, a man who trained in Hamon to continue the legacy of his father Mario and grandfather Will. However, the group arrives too late to prevent Kars, Wamuu, and Esidisi from awakening. Joseph plays on Wamuu's pride and convinces Wamuu to let him live to be a more worthy opponent. Both Wamuu and Esidisi implant poison-filled rings in his aorta and windpipe, giving Joseph 33 days to get the antidotes from each of them.