The night after WrestleMania on the April 2 episode of "Raw", the Hardys competed in a 10-team battle royal for the World Tag Team Championship. They won the titles from then WWE Champion John Cena and Shawn Michaels by last eliminating Lance Cade and Trevor Murdoch. They then began a feud with Cade and Murdoch, with the Hardys retaining the Championship in their first title defense against them at Backlash and again at Judgment Day. The Hardys then defended their titles against The World's Greatest Tag Team in a Ladder match at One Night Stand. However, the next night on "Raw", the Hardys lost the titles to Cade and Murdoch, competing through injuries sustained in their previous night's ladder match. The Hardys earned a rematch at but were defeated.