In 1995, he moved to Ohio University where he served as the quarterbacks coach for two seasons, and was promoted to offensive coordinator in 1997. During his first season with Ohio, his offense had measurable success, particularly in a game against Eastern Michigan, in which the school totaled 612 yards, second most in school history. The team also captured a win against Maryland in 1997, which was Ohio's first victory over a school from the ACC. The following week, Ohio fell three points short of defeating Kansas State. In Calhoun's final year at Ohio in 2000, the offense set a school record with 418.1 yards per game and rushed for a school-best 3,553. The Bobcats also ended the season with wins over two bowl teams, Minnesota and Marshall.