DeShannon continued to record into the 21st century. She released "You Know Me", an album of original songs, for Varèse Sarabande in 2000, and "When You Walk in the Room", a new recording of her best-known songs, in 2011. She was portrayed by singer Liz Phair in an episode of "American Dreams". On June 17, 2010, DeShannon was inducted into the Songwriters Hall of Fame. In 2012 she wrote and recorded "For Africa, In Africa," a song inspired by the urgent need for action to provide clean water for the African Continent. Using her continuing access and friendship with Paul McCartney and Ringo Starr, DeShannon has appeared as a contributing entertainment broadcast correspondent reporting historical anecdotes and current touring and personal news and publicity pertaining to the two surviving Beatles for "Breakfast with the Beatles" on Sirius XM Satellite Radio on the weekends since October 2009.