In 1876 an act of parliament made it possible for women to be admitted to examination in medicine. The Edinburgh Seven that set up the London School of Medicine for Women (LSMW) asked Thorne, who agreed to hold the position of Honorary Secretary from 12 June 1877 – 1908, and a seat on the executive, although she never actually qualified in medicine. Thorne gave up her own ambition to be a doctor in order to commit herself to helping the school run smoothly; to become more solidly established. But Dr Lucy Sewall had once written that of all the students at Edinburgh, Isabel Thorne was one most likely to make the best doctor. She was considerate, tactful, hard-working, industrious, and for 30 years the mainstay of the college administration.