Raúl scored his first goal for the club during his first match on 1 August 2010 with a brace in a 3–1 victory over Bayern Munich in the final match of the pre-season competition LIGA total! Cup 2010. One week later, he made his competitive debut in the 2010 DFL-Supercup on 7 August 2010 again against Bayern, but this time he failed to score in the 2–0 defeat. Raúl made his Bundesliga debut on 21 August 2010 in a 2–1 defeat against Hamburger SV. and scored his first goal for Schalke in the Bundesliga against Borussia Mönchengladbach on 25 September 2010 in a 2–2 draw. After a quiet start, he rediscovered his goalscoring form in the Bundesliga with a brace against FC St. Pauli on 5 November in a 3–0 win, and on 20 November, he scored his first hat-trick for the club in a 4–0 win over Werder Bremen. On 18 December, he scored his second hat-trick for Schalke in a 3–0 win against 1. FC Köln.