The Father of Railways, George Stephenson, built the first public inter-city railway line in the world, the Liverpool and Manchester Railway, which opened in 1830. With his role in the marketing and manufacturing of the steam engine, and invention of modern coinage, Matthew Boulton (business partner of James Watt) is regarded as one of the most influential entrepreneurs in history. The physician Edward Jenner's smallpox vaccine is said to have "saved more lives ... than were lost in all the wars of mankind since the beginning of recorded history."