The best known of Technicon's CFA instruments are the AutoAnalyzer II (introduced 1970), the Sequential Multiple Analyzer (SMA, 1969), and the Sequential Multiple Analyzer with Computer (SMAC, 1974). The Autoanalyzer II (AAII) is the instrument that most EPA methods were written on and reference. The AAII is a second generation segmented flow analyzer that uses 2 millimeter ID glass tubing and pumps reagent at flow rates of 2 - 3 milliliters per minute. Typical sample throughput for the AAII is 30 - 60 samples per hour. Third generation segmented flow analyzers were proposed in the literature, but not developed commercially until Alpkem introduced the RFA 300 in 1984. The RFA 300 pumps at flow rates less than 1 milliliter per minute through 1 millimeter ID glass mixing coils. Throughput on the RFA can approach 360 samples per hour, but averages closer to 90 samples per hour on most environmental tests. In 1986, Technicon (Bran+Luebbe) introduced its own microflow TRAACS-800 system.