Grey stood for parliament at South Northumberland in 1878 and polled in the election the same number of votes as his opponent Edward Ridley, but Grey declined a scrutiny and was not returned. It was not until the general election of 1880 that Grey, the Liberal Party candidate, was elected as a member of parliament (MP) for South Northumberland, a seat he held until it was replaced under the Redistribution of Seats Act 1885 and he moved to be the MP for Tyneside, following that year's election. In 1884 he wrote to the Manchester-based "Women's Suffrage Journal" declaring his support for women's suffrage, writing that "here are no questions which receive so little attention, or which, in my opinion, so urgently call for the close and serious consideration of social reformers, as those affecting the condition of women. The possession of a vote by women who are heads of households will lead to the formation of associations and unions for the protection and advancement of the interests of their sex."