George Williams (Roger Bart) is a pharmacist who begins a relationship with Bree after her discovery of her husband's extramarital affair with the neighborhood prostitute, Maisy Gibbons. Their relationship goes well until Bree accidentally fires a handgun at George's foot, causing him to lose a toe. He returns after a short absence and begins to lust after Bree. Rex takes offense to this, and it culminates with George being pushed into a pool at Carlos' going-away party. Motivated by his obsession for Bree, George begins replacing Rex's heart medication with dangerous amounts of potassium, causing the latter's death in "One Wonderful Day".