"Crash Twinsanity" was showcased alongside other VU Games titles at the Game Stars Live consumer games show held at ExCeL London from September 1–5, 2004. VU Games' booth featured a "Challenge Corner" where attendees competed for "Crash" and "Spyro"-based prizes. The game went gold on September 7, 2004, and was released in North America on September 28, 2004 and in Europe on October 8, 2004. A version for the GameCube was announced, but not released; "IGN" speculated that the port's cancellation was due to the disappointing financial performance of other VU Games titles on the system. In the United Kingdom, "Crash Twinsanity" debuted at #25 in the sales charts, and remained within the top 40 best-sellers by the 2004 Christmas season.