Following shakedown, "Yukon" was assigned to the Service Force Atlantic Fleet. During the first two years of her resumed service, the ship made 13 round-trip voyages between the United States and the West Indies. In December 1941, however, her zone of operations was changed to the North Atlantic, and she made a voyage to Reykjavík, Iceland. While returning to the United States from Iceland on 23 January 1942, "Yukon" suffered partial disability when her main air compressor went out. Two days later, came to her aid and took the ship in tow for Reykjavík. On the 29th, "Hamilton" turned her charge over to the British tug and took up escort station.