By finishing the regular season of the Apertura 2014 as second place with 31 units, Tigres advanced to Copa Libertadores 2015 as Mexico 1 to play in Group 6 against River Plate, San José and Juan Aurich. On 18 February 2015, Tigres defeated Juan Aurich by 3–0 at the Estadio Universitario with two goals of Joffre Guerrón and one of Jesús Dueñas. On 5 March, with goal of Guerrón, Tigres tied 1–1 against River Plate at the Estadio Monumental. On 11 March, Tigres defeated San José by 1–0 with goal of Amaury Escoto at the Estadio Jesús Bermúdez. Tigres won by 4–0 against San José at the Estadio Universitario with two goals of Rafael Sóbis, and goals of Guerrón and Egidio Arévalo on 17 March. On 8 April, Tigres received River Plate for a high-profile match in the Estadio Universitario. River Plate needed to win or tie to remain in the fight for a ticket to the next phase. At 11' Egidio Arévalo scored the 1-0 for Tigres. The team kept the match under control and at 68' Damián Alvarez scored the 2–0. After a defensive mistake from José Rivas and Hugo Ayala, Teofilo Gutierrez scored the 1–2 at 86' for River Plate. Rodrigo Mora scored the 2–2 at the 89'. On 15 April, Tigres played against Juan Aurich at the Estadio Elías Aguirre.