Sykes made his World Superbike Championship debut at Brands Hatch as a wildcard, impressing by qualifying sixth (ahead of three works Suzukis with more powerful engines, including title contender Max Neukirchner). He retired from a strong position in race 1 due to a hole in the radiator by rocks thrown up by Max Biaggi's Sterilgarda Ducati machine, but came back to finish 6th in race 2. He gained a second wildcard meeting at Donington Park in changeable conditions, where he proved even stronger. He again qualified on the second row, but got a flying start in race one and had a comfortable lead when the race was red-flagged due to oil from Noriyuki Haga's Yamaha. Knowing he had to finish within 4 seconds of Troy Bayliss to win on aggregate, Sykes lead early in race two, before easing off after seeing a white flag with a red cross, which typically means a slippery surface (often with the yellow and red striped oil flag), but racing in British Superbike Championship races, the flag neutralises the race under a full-course caution period with safety car deployment, so Sykes and Leon Haslam both eased up, anticipating neutralisation, but the time lost here proved costly, as Sykes failed to stay close enough to Bayliss, finishing second behind the three-time series champion. He was less competitive in race two, but his reputation had still been boosted.