Other railways that Fowler consulted for were the London Tilbury and Southend Railway, the Great Northern Railway, the Highland Railway and the Cheshire Lines Railway. Following the death of Isambard Kingdom Brunel in 1859, Fowler was retained by the Great Western Railway. His various appointments involved him in the design of Victoria station in London, Sheffield Victoria station, St Enoch station in Glasgow, Liverpool Central station and Manchester Central station. The latter station's wide train shed roof was the second widest unsupported iron arch in Britain after the roof of St Pancras railway station.