Initially, Arran was a Protestant and a member of the pro-English party. In 1543 he helped to negotiate the marriage of the Queen of Scots to the infant Prince of Wales (the future Edward VI of England); in the same year he authorised the translation and reading of the Bible in the vernacular. On 27 January 1543 he arrested Cardinal Beaton, who favoured the Auld Alliance. Beaton was imprisoned at Dalkeith Palace and then Blackness Castle. However, Henry VIII of England doubted Arran's commitment to English policy and wanted him deposed. On 18 March 1543, Sir George Douglas of Pittendreich, brother of the Earl of Angus, told the English ambassador, Ralph Sadler, that: