Grey is the protagonist and focal point of the series. She has been called "intelligent, compassionate, hard-working, oftentimes outspoken, easily distracted, and indecisive" by "Grey's Anatomy" executives. Pompeo says she is unaware if her character knows how to have fun, adding: "All of my scenes with are the same—we're either breaking up or having sex." Her personality has evolved over the past few seasons from depressed, to happy and "fixed". Pompeo said to "Good Morning America", "I am so incredibly lucky to have Patrick [Dempsey, to have the chemistry that we do, we have an amazing relationship, and it's like any other relationship, you have your ups and downs. But we work it out, and we've found a way to do this for this long and still get along, and make it work and believe in what we're doing." Pompeo told "Entertainment Weekly": "It's awkward with Patrick because he's like my brother. As soon as the camera is off, I'm like, 'Is your hand on my butt?' But there are millions of girls who have been waiting for this, so I feel an obligation to the fans." Rhimes used the dog "Doc", which Meredith and Derek shared, as a metaphor for their relationship during the second season. She characterizes Grey as doing what she thinks is right: