Lenore Romney worked on behalf of many volunteer organizations over a number of years. In 1963, she was co-chair of the Muscular Dystrophy Association. Starting in 1965, she was a member of a special committee of the American Mothers Committee. By 1970, she was on the national board of directors of the YWCA and a member of the national advisory board to American Field Services. She had also held high positions with Goodwill Industries, United Community Services, Child Guidance Study, Association for Retarded Children, Michigan Association for Emotionally Disturbed Children, and the Michigan Historical Society. She worked with Project HOPE. She was chair of the Detroit Grand Opera Association and was active with the Women's Association for the Detroit Symphony Orchestra. "The Boston Globe" later characterized her as a "pillar of Detroit society".