New York State Route 106 (NY 106) is a state highway located in Nassau County, New York, in the United States. It begins in the town of Hempstead at an intersection with NY 105 in North Bellmore and heads to the north, crossing the hamlets of East Meadow and Levittown before entering the town of Oyster Bay. In Hicksville, NY 106 becomes concurrent with NY 107, an overlap colloquially known as the "One oh Six–One oh Seven". The concurrency ends immediately after an interchange with Jericho Turnpike in the hamlet of Jericho. After breaking away from NY 107, NY 106 heads north across the villages of Brookville and Muttontown and the hamlet of East Norwich to the hamlet of Oyster Bay, where the route ends one block south of Oyster Bay Harbor.