A NASA multi-center Technology Applications Assessment Team led from the Johnson Spaceflight Center, has as of January 2011 described "Nautilus-X", a concept study for a multi-mission space exploration vehicle useful for missions beyond low Earth orbit (LEO), of up to 24 months duration for a crew of up to six. Although Nautilus-X is adaptable to a variety of mission-specific propulsion units of various low-thrust, high specific impulse (Isp) designs, nuclear ion-electric drive is shown for illustrative purposes. It is intended for integration and checkout at the International Space Station (ISS), and would be suitable for deep-space missions from the ISS to and beyond the Moon, including Earth/Moon L1, Sun/Earth L2, near-Earth asteroidal, and Mars orbital destinations. It incorporates a reduced-g centrifuge providing artificial gravity for crew health to ameliorate the effects of long-term 0g exposure, and the capability to mitigate the space radiation environment.