Gennett is best remembered for the wealth of early jazz talent recorded on the label, including sessions by Jelly Roll Morton, Bix Beiderbecke, The New Orleans Rhythm Kings, King Oliver's band with the young Louis Armstrong, Lois Deppe's Serenaders with the young Earl Hines, Hoagy Carmichael, Duke Ellington, The Red Onion Jazz Babies, The State Street Ramblers, Zack Whyte and his Chocolate Beau Brummels, Alphonse Trent and his Orchestra and many others. Gennett also recorded early blues and gospel music artists such as Thomas A. Dorsey, Sam Collins, Jaybird Coleman, as well as early hillbilly or country music performers such as Vernon Dalhart, Bradley Kincaid, Ernest Stoneman, Fiddlin' Doc Roberts, and Gene Autry. Many early religious recordings were made by Homer Rodeheaver, early shape note singers and others.