Following The Rezort, Power was cast as a lead role alongside actors Billy Boyd, Alice Lowe, and Eline Powell in the Lennox Brothers debut feature "Stoner Express (a.k.a. AmstarDam)", a marijuana-fuelled fairytale shot in Amsterdam and London. In the film notorious author and cannabis smuggler Howard Marks played himself, this was his last film before he died in 2016. In 2016, Power created, directed and shot 10 episodes of "Chinese Girls in London", a short format comedy series with an all-Chinese cast. The show was optioned by Roughcut Tv Productions with the pilot episode to be shown on BBC 3 in late 2017. During this time, Power was cast as Mitch, in Mick Jackson’s Bafta-nominated Denial, followed up by Lt Brett Biggle in Brad Pitt’s satirical war film, War Machine. In 2017 Power was reunited with Woody Harrelson working on his directorial debut Lost in London. The film was the first ever, to be shot in a single take, with one camera and streamed live to audiences in over 500 American theatres. Power followed this up with a role in Mark Strong’s series Deep State, which was filmed through late 2017 and released at the end of 2018. In 2019, Sean teamed up with Irish production company Wytao Film's William Morgan and Vincent Walsh to shoot the award winning comedy Double Denim. In early 2020 he was cast as Bradley in Anna Paquin's series "Flack".