In 1933, producer Darryl F. Zanuck cast Keeler in the Warner Bros. musical "42nd Street" opposite Dick Powell and Bebe Daniels. The film was a huge success due to Busby Berkeley's lavish innovative choreography. Following "42nd Street", Jack L. Warner gave Keeler a long-term contract and cast her in "Gold Diggers of 1933", "Footlight Parade", "Dames" and "Colleen". Keeler and Jolson starred together in "Go into Your Dance", which was their only film together. They are satirized in Frank Tashlin's 1937 cartoon "The Woods Are Full of Cuckoos". Jolson and Keeler appeared on Broadway one last time together for the unsuccessful show "Hold on to Your Hats".