Some cultures proscribe sexual relations between clan-members, even when no traceable biological relationship exists, while members of other clans are permissible irrespective of the existence of a biological relationship. In many cultures, certain types of cousin relations are preferred as sexual and marital partners, whereas in others these are taboo. Some cultures permit sexual and marital relations between aunts/uncles and nephews/nieces. In some instances, brother–sister marriages have been practised by the elites with some regularity. Parent–child and sibling–sibling unions are almost universally taboo.