After retiring from the NBA and moving his family back to his adopted hometown of Portland, Oregon, Grant was diagnosed with Parkinson's Disease in November 2008. With new friends in Michael J. Fox and Muhammad Ali, who share the disease with Brian, he decided to recreate the Brian Grant Foundation; this time, with a new focus and mission. The new charity supports efforts toward the education and awareness of Parkinson's disease in order to increase earlier diagnosis, educate patients and their families, and provide a viable forum for people affected by the disease. The mission of the foundation is to help those impacted by Parkinson's to live active and fulfilling lives. The foundation hosts an annual fundraiser, Shake It Till We Make It, to raise money to provide support and resources for all those affected by Parkinson's disease. Shake It Till We Make It is a two-day celebrity gala and golf tournament hosted in Portland, Oregon.