George then finds out the police are closing in on him and have also searched his house after Bree went to the police, suspecting George was involved in Dr. Goldfine's attack. George retreats to a hotel room (in the same hotel where Bree is co-hosting a charity event) and has a bellman give her a note. He then overdoses on sleeping pills which ultimately leads to his death. George makes his final appearance in series finale, as one of the ghosts watching over Susan as she leaves Wisteria Lane.