Many PBF organizations have a primary mission of helping patients get to distant locations when the patients cannot afford other transport, a drive would be too long, or circumstances prevent commercial airline flight, such as being in a rural area where no commercial air service is available or having an immune-compromised condition such that flight by airline would expose them to too many strangers. PBF organizations that provide these services include Angel Flight, LifeLine Pilots, Volunteer Pilots Association, and many, many more.