Having met Lord Cholmondeley at the Pantheon in 1776, she began a liaison with him that lasted for three years. Their friends included the courtesans Gertrude Mahon and Kitty Frederick. Thomas Gainsborough painted two portraits of her in 1778, which are in the Frick Collection and the Metropolitan Museum of Art. In 1782, she had a short, concealed intrigue with the Prince of Wales (afterwards George IV) and gave birth to a daughter on 30 March 1782, who was baptised at St Marylebone as Georgiana Augusta Frederica Seymour (d. 1813) but used the name Georgina Seymour.