Cardinal-Princes D. Afonso (1509–1540) and D. Henrique (1512–1580), sons of D. Manuel I of Portugal (1469–1521) administrated the main Portuguese dioceses through the 16th century. Afonso administrated the Évora and Lisboa dioceses until his death. Henrique was successively Archbishop of Braga, Lisboa and Évora, as well as head of the Portuguese Inquisition. He became King of Portugal when his grand-nephew Sebastião I (1554–1578) died at Alcácer-Quibir (1578). As princes, they had their personal chapels and imposed a magnificent liturgy in the cathedrals they administrated.