In 1960, Best appeared in the episode "Love on Credit" of CBS's anthology series "The DuPont Show with June Allyson". The same year, he guest-starred on "The Andy Griffith Show" as "The Guitar Player" (Season 1, Episode 3 and 31). He starred in three episodes of "The Twilight Zone" including "The Grave" (Season 3, Episode 7), "The Last Rites of Jeff Myrtlebank," (Season 3, Episode 23) and "Jess-Belle" (Season 4, Episode 7). In 1961 he guest-starred in the "Alfred Hitchcock Presents" episode "Make My Death Bed". In 1963, he was cast as the courageous Wisconsin game warden Ernie Swift in the episode "Open Season" of another CBS anthology series, "GE True", hosted by Jack Webb. In the story line, Swift faces the reprisal of organized crime after he tickets gangster Frank MacErlane (David McLean) for illegal fishing.