Pearl founded the Constitutional Clinic at the Johns Hopkins Hospital. He believed in constitutional medicine, which focuses on examining the soil on which a seed falls. He later became the director of a new Institute of Biological Research at Johns Hopkins in 1925 that was aimed at examining the genetics and environmental factors of disease. This research institute combined biometry, genetics, and medicine to investigate the hereditary predisposition of tuberculosis and hypertension. When conducting his research of these diseases, Pearl recorded the height, weight, handedness, measurements of different body parts, and physical descriptions. Just like Galton, he believed that race was an important factor in human characteristics and believed in using biology and genetics to improve the long-term health of the population. Although he tried to be quantitative, objective, and systematic, his classifications of different races were influenced by social norms and prejudices.