On 10 January 2018, during a live press conference in London, Khan signed a three-fight deal with Eddie Hearn at Matchroom Sport. The deal meant Khan would fight exclusively on Sky Sports, with his return bout in the UK taking place on 21 April at the Echo Arena in Liverpool. on 29 January, Phil Lo Greco (28–3, 17 KOs) was announced as his opponent. At the official press conference, a brawl broke out after Lo Greco made comments about Khan's personal life, "After the Canelo loss you went on a losing streak – family, wife and then you go out and tweet to the heavyweight champion of the world. What is wrong with you, mate?" Khan responded by throwing his glass full of water towards Lo Greco. The bout was fought at a catchweight of 150pounds, as requested by Lo Greco's team. Khan trained with Joe Goosen for the fight, with Virgil Hunter unavailable due to ill health. The fight would be the first boxing main event to stream on ESPN's new streaming service ESPN+.