Some time later, April fought alongside the Turtles, Mona Lisa, and Karai to put an end to the rogue Salamandrian called "the Newtralizer". When he blasts with his electrical bursts, she defended herself by erecting a yellow shield out of telekinetic energy. She used her extraordinarily strong telekinesis to open the water pipes, which appeared to weaken and disorient him. When Lord Dregg later invaded, she joined Raphael, Mona Lisa and Bishop in the Turtle Mech to try and overpower his spaceship. Once confronting Dregg directly, she tried to hold him off with her tantō sword but he proved too strong.