What is now US 130 was a part of two Lenape trails: the Pensaukin Trail, running from what is now Camden to Crosswick; and the Lower Assunpink or Crosswicksung Trail, running from there north to Ahandewamock Village, near modern-day New Brunswick. The section of this trail between Crosswicks and Cranbury became part of a King's Highway connecting South Amboy and Salem. North of Cranbury, the Assunpink trail was later called the Lower Road, then George's Road. The route was incorporated into several turnpikes in the 19th century. In 1808, the Burlington Turnpike was chartered to run from Burlington north to the Trenton and New Brunswick Turnpike through Bordentown. The Bordentown and South Amboy Turnpike was chartered in 1818 to run from Bordentown to South Amboy, bypassing the King's Highway from East Brunswick to Cranbury. In 1849 the Westfield and Camden Turnpike was legislated along the Burlington Road from Camden to the bridge at Rancoas Creek. The New Brunswick and Cranbury Turnpike was chartered in 1865 to run from the Bordentown-South Amboy Turnpike to New Brunswick along the old George's Road.