From 1825 to 1920 the Miami and Erie Canal divided Cincinnati's residential neighborhood of Over-the-Rhine from the business district of downtown. The canal was used to transport goods and people from the Great Lakes to the Ohio River and subsequently the Mississippi River via Cincinnati, until the popularity of railroads caused it to become disused. The canal then became very polluted due to people dumping trash in it and using it as a sewer. The canal became unprofitable by 1856 and was abandoned by the city in 1877.