"The Great American Fraud" (1905) by Samuel Hopkins Adams revealed fraudulent claims and endorsements of patent medicines in America. This article shed light on the many false claims that pharmaceutical companies and other manufacturers would make as to the potency of their medicines, drugs and tonics. This exposure contributed heavily to the creation of the Pure Food and Drug Act alongside Upton Sinclair's work. Using the example of Peruna in his article, Adams described how this tonic, which was made of seven compound drugs and alcohol, did not have "any great potency". Manufacturers sold it at an obscene price and hence made immense profits. His work forced a crackdown on a number of other patents and fraudulent schemes of medicinal companies.