In 1818, the Quapaw tribe ceded all its land north of the Canadian to the United States, thus making this river the effective southern boundary of the new nation. In 1825, the Osage ceded their claims to land along the river. The Canadian was designated as the boundary between the Creek-Seminole lands on the north side and the Choctaw (and later the Chickasaw) on the south side. Major Stephen H. Long led an expedition up the Canadian River in 1821. He proclaimed the land along the river as the "Great American Desert." Despite this assessment, trading posts were established along the river, starting with Edwards' Post at the mouth of Little River. Camp Holmes was established by Colonel Henry Dodge's Dragoons in 1834. Captain Nathan Boone led a dragoon troop up the river to the 100th Meridian, which was then the western border of the United States.