The central claim of what is often called "Cartesian dualism", in honor of Descartes, is that the immaterial mind and the material body, while being ontologically distinct substances, causally interact. This is an idea that continues to feature prominently in many non-European philosophies. Mental events cause physical events, and vice versa. But this leads to a substantial problem for Cartesian dualism: How can an immaterial mind cause anything in a material body, and vice versa? This has often been called the "problem of interactionism."