Tilghman Street was eventually connected directly from Cetronia to Allentown by a bridge over Cedar Creek; Tilghman Street (west of the Lehigh River) and Union Boulevard (east of the river) were joined in 1929 by a bridge. By 1936, US 22 had been moved from its Hamilton Street and Broad Street alignment to Tilghman Street and Union Boulevard through Allentown and Bethlehem. When the Lehigh Valley Thruway was completed in 1954, US 22 was moved onto it. With the completion of Interstate 78, US 22 was moved onto that highway from Fredericksburg to Kuhnsville.