Mosley eventually TKO'd Margarito in the ninth round, after appearing to win every round up until then, in a massive upset. Sugar Shane utterly dominated Margarito, using his superior hand speed, pinpoint accuracy, consistent body punching, countless huge right hands to the jaw and tying up when Margarito backed him into the ropes, to wear Margarito down and stop him—something that many seasoned boxing observers thought was nigh-on impossible. After knocking him down with a series of heavy overhand rights at the end of the eighth round, Margarito was unable to avoid punches during a heavy barrage from Mosley early on in the ninth, forcing the referee to step in as Margarito slumped to the canvas a second time. Margarito had never previously been stopped. It was a sensational win for Sugar Shane and propelled him back to the upper echelons of the welterweight division and the sport of Boxing, in addition to further cementing his legacy as one of the best fighters in his era.