In Mayes County, the highway has an interchange with US-412 south of Chouteau. US-69 creates a spur to Sportsman Acres, SH-69A. The route then intersects SH-20 in Pryor and SH-28 in Adair. US-69 leaves Mayes County and enters Craig County south of Big Cabin. As the route approaches Big Cabin, signage affixed to the side of parked truck trailers warns of a speed zone, due to Big Cabin's former speed trap status. The trap was shut down by the Oklahoma Department of Public Safety on August 1, 2005. Just north of the town, US-69 has the first of three interchanges with Interstate 44, the Will Rogers Turnpike. After crossing the turnpike, the route begins a concurrency with US-60 into Vinita. The two U.S. routes serve as the southern terminus of SH-2 there. East of town, another access point to the turnpike is offered. SH-82's northern terminus lies east of this.