The 2010 United States Census indicates Tuscola County had a 2010 population of 55,729. This is a decrease of -2,537 people from the 2000 United States Census. Overall, the county had a -4.4% growth rate during this ten-year period. In 2010 there were 21,590 households and 15,423 families in the county. The population density was 69.4 per square mile (26.8 square kilometers). There were 24,451 housing units at an average density of 30.4 per square mile (11.7 square kilometers). 96.1% of the population were White, 1.1% Black or African American, 0.5% Native American, 0.3% Asian, 0.7% of some other race and 1.2% of two or more races. 2.8% were Hispanic or Latino (of any race). 32.3% were of German, 9.0% English, 8.4% Polish, 8.0% Irish, 7.8% American and 6.2% French, French Canadian or Cajun ancestry.