"Picuda" was assigned to Submarine Division 201, Squadron 20, U.S. Atlantic Fleet. She remained in the Portsmouth Naval Shipyard for major overhaul until 18 October. She shifted to the Submarine Base at New London on 31 October for duty as a training ship for the Submarine School. "Picuda" put to sea from New London 12 November for a training cruise which included visits to Key West, Florida, and Havana, Cuba. Upon her return to New London, 26 November, she was assigned to the New London Group of 16 November (Inactive) Fleet. She shifted to the Portsmouth Naval Shipyard on 12 December to commence preservation incidental to being placed in inactive status. On 15 January 1946, "Picuda" was ordered to cease inactivation and report to the Second Fleet for duty as a unit of Submarine Division 81, Squadron 8, U.S. Atlantic Fleet.