At the US Open, Pironkova reached the third round of a Grand Slam besides Wimbledon for the first time. She defeated Camila Giorgi in the first round, Ayumi Morita in the second, and Silvia Soler Espinosa in the third. In the fourth round, with a first US Open quarterfinal in sight, she was upset by former world No. 1, Ana Ivanovic. Her last tournament of the year was the Tournament of Champions, where she entered with a wild card. She lost to Caroline Wozniacki in the semifinals.