From 20 September to 29 November 1944, "Saury" conducted her eleventh and last war patrol. She patrolled in the Nansei Shoto area from 20 September to 4 November, rescuing a downed pilot, but sinking no enemy ships as she hunted in the wake of the fast carrier forces. After stopping at Saipan from 5 to 10 November, she proceeded on the second phase of the patrol, an antipatrol vessel sweep north of the Bonin Islands. Extremely poor weather again interfered, but on 18 November, she damaged a tanker. On 29 November, she returned to Pearl Harbor.