Entering the playoffs as the top seeded team in both leagues, they defeated the AL Wild Card winner Tampa Bay Rays in five games in the ALDS, advancing to the ALCS for the third year in a row to face the New York Yankees. In Game 6 at Minute Maid Park, Jose Altuve hit a walk-off home run to win the pennant and send the team to its third World Series appearance. However, they lost the 2019 World Series to the Washington Nationals in seven games, taking three games in Washington but losing all four of their games at home.