Upon his return to Antwerp, where he was registered in the local Guild of Saint Luke as a "wijnmeester" (wine master) (a title reserved for the children of members of the guild) in 1650–51. He married Maria Blanckaert, daughter of the painter Jan Blanckaert. His wife's mother was a sister of the painters and art dealers Cornelis de Wael (whom he knew from Genoa) and Lucas de Wael. Two of the couple's sons Jan Baptist Boel the Younger and Balthasar-Lucas Boel became artists.