Barrera fought Pacquiao in a rematch bout for the WBC International super featherweight title on October 6, 2007 in Las Vegas. Barrera was defeated by a unanimous decision with scores of 118–109, 118–109, 115–112. After the match, Barrera expressed his desire to retire from boxing, however no official confirmation had been given. On February 13, 2008, Barrera announced to the media that he would fight the winner of the Márquez vs. Pacquiao bout on March 15. The winner of this turned out to be Pacquiao, in a highly disputed split decision. However, Pacquiao's move to the lightweight division and subsequent capture of the WBC lightweight title ensured that a third fight between the two would not happen.