In a legal career that has spanned four decades, Allred has represented a wide variety of clients in civil rights suits that have involved sexual harassment, women's rights, wrongful termination, and employment discrimination. "The New Republic" has called her "a longtime master of the press conference." She often takes high-profile cases, using press conferences and appearances on television to much effect. Allred has represented many clients in suits against celebrities, including those against Mötley Crüe drummer Tommy Lee, Arnold Schwarzenegger, Herman Cain, David Boreanaz, Scott Lee Cohen, Anthony Weiner, Sacha Baron Cohen, Esai Morales, and R Kelly.