It is used in the same roles as the NATO .50 BMG (12.7×99mm NATO) cartridge. The two differ in bullet shape and weight, and the casing of the 12.7×108mm is slightly longer, and its larger case capacity allow it to hold slightly more of a different type of powder. The 12.7×108mm can be used to engage a wide variety of targets on the battlefield, and will destroy unarmored vehicles, penetrate lightly armored vehicles and damage external ancillary equipment (i.e.: searchlights, radar, transmitters, vision blocks, engine compartment covers) on heavily armored vehicles such as tanks. It will also ignite gasoline and—since 2019—diesel fuel. Armor-piercing ammunition will penetrate around 25 mm of armor. Normal full metal jacket ammunition will only dimple tank armor, causing no damage.