The district has significant road infrastructure and National Highway 3 which runs from Phnom Penh to Veal Rinh runs along the eastern edge of the district from north to south. Borsedth District is one of the smaller districts in Kampong Speu province by land area but has one of the largest district populations in the province due to well irrigated land and good transport infrastructure. National Road 124 crosses the district, entering from the north and exiting in the south to join National Highway 3 further south in Dang Tong district of Kampot Province. Numerous smaller tertiary roads cross the district running either north to Kong Pisei and then to the provincial capital or east toward National Highway 3.