The original starring cast consisted of Anthony Edwards as Dr. Mark Greene, George Clooney as Dr. Doug Ross, Sherry Stringfield as Dr. Susan Lewis, Noah Wyle as medical student John Carter, and Eriq La Salle as Dr. Peter Benton. As the series continued, some key changes were made: Nurse Carol Hathaway, played by Julianna Margulies, who attempts suicide in the original pilot script, was made into a regular cast member. Ming-Na Wen debuted in the middle of the first season as medical student Jing-Mei "Deb" Chen, but did not return for the second season; she returns in season 6 episode 10. Gloria Reuben and Laura Innes would join the series as Physician Assistant Jeanie Boulet and Dr. Kerry Weaver, respectively, by the second season.