In "Sexual Ecology," Rotello made a number of warnings and predictions, many of which have proved prescient and some not. He predicted that as new drugs effectively treated HIV, fear would abate and condom use would likely diminish, which has occurred. He predicted that treatment could become a form of prevention by lowering group infectivity, which has also occurred. But he warned that if gay men responded to the availability of treatment by increasing unsafe sex and increasing multipartnerism - the phenomenon of so-called 'risk compensation' - then “the decline in infectivity could easily be outbalanced by a rise in the unsafe contact rate” leading to a continuing epidemic. This has also occurred.