Keyport High School's interscholastic sports include: football, basketball, cheerleading for football/basketball, field hockey, wrestling, baseball, softball, track and field, cross country, indoor track, soccer, and tennis. The school participates as the host school / lead agency for joint cooperative girls soccer, boys / girls volleyball and wrestling teams with Henry Hudson Regional High School, while Henry Hudson is the host school for cross country running, boys / girls tennis and winter track teams. Keyport is also the lead agency / host school for joint field hockey and football teams with Keansburg High School. These co-op programs operate under agreements scheduled to expire at the end of the 2023–24 school year.