"La Isla Bonita" debuted at number 49 and reached a peak of number four for three consecutive weeks on the "Billboard" Hot 100 chart in May 1987. The song was Madonna's second number one single on the Adult Contemporary chart, following 1986's "Live to Tell". It became the 11th consecutive top-five hit for Madonna, a feat surpassed only by the Beatles and Elvis Presley. The single also found success on the Hot Dance Singles Sales chart, where it peaked at number one. In Canada, the song debuted at number 74 for the issue dated April 4, 1987 and reached the top of the chart in its tenth week on the issue dated June 6, 1987, remaining on the chart for 25 weeks. It placed at number 22 on the "RPM" Year-end chart for 1987.