As she entered adulthood, Rose Marie turned to nightclub and lounge performances. According to her autobiography, "Hold the Roses," she was assisted in her career by many members of organized crime, including Al Capone and Bugsy Siegel. Rose Marie secured work at the Flamingo Hotel in Las Vegas, Nevada, which was built by Siegel. Because of the Flamingo's organized crime ties, she had to seek permission to perform in other casinos and remained loyal to "the boys" at the Flamingo for the rest of her life.