In "Jurassic World", Dr. Wu is first seen with Claire Dearing trying to attract investors with the genetically modified hybrid "Indominus rex", using the genetics of the "Tyrannosaurus rex", pit viper, tree frog, cuttlefish, "Velociraptor", "Carnotaurus", "Therizinosaur", "Gigantosaurus", and other animals. After the "Indominus" escapes, Wu declines to specify the animal's genetic make-up, stating that he is not at liberty to reveal such information. When Masrani informs Wu of the "Indominus"s ability to camouflage and to regulate its body temperature, Wu reveals that the animal includes tree frog and cuttlefish DNA, allowing it to do such things. Outraged, Masrani orders Wu to shut down his operations, but Wu reminds him that the geneticists have always used the DNA of other animals to fill gaps in the dinosaurs' genomes. Wu further states that many of the dinosaurs would look "quite different" if their genetic codes were pure. Wu is later revealed to have been secretly working with InGen Security head Hoskins to create the "Indominus rex" as a weapon. Hoskins has Wu and his InGen Security team flown from the island to an unknown location along with dinosaur embryos, thus protecting his research.