In 1974, upon the death of their brother, James M. Cox (known as "Jim Jr."), Chambers and her sister Barbara Cox Anthony gained a controlling interest in the family company. That same year Chambers became chairwoman of Atlanta Newspapers. Anthony became chairwoman of Dayton Newspapers, while her husband, Garner Anthony, became the administrative head of Cox Enterprises. In 1988 Anthony's son James Cox Kennedy became chairman and chief executive officer. Henceforth Chambers remained a close advisor concerning the daily operation of the company.