Following the example of Mendelssohn, Reggio endeavored to extend the knowledge of Hebrew among the Jewish masses by translating the Bible into Italian language and writing a commentary thereon. His simple but clear and attractive style made a deep impression not only on the Italian but even on the German Jews. Although he believed that in the main the text of the Bible has been well guarded against corruption, yet he admitted that involuntary scribal errors had slipped in and that it would be no sin to correct them ("Iggerot Yashar," Letter V.). The reproaches of Meïr Randegger (d. 1853) concerning his Biblical corrections Reggio answered by stating that every one was permitted to interpret the text according to his understanding, provided such interpretations were not in opposition to the principles of the Jewish religion (ib. Letter XXX.).