"Say My Name" debuted at number 83 on the "Billboard" Hot 100, and reached its peak position twelve weeks later after selling 134,000 physical singles during its first week, taking longer than any other Destiny's Child number-one single to reach the top. The song also reached the top of both the Hot 100 Airplay and the Hot R&B/Hip-Hop Singles & Tracks chart for three weeks in 2000. The song spent 32 weeks on the Hot 100 and was one of the top ten best-selling CD-singles of the year in the US. It is the group's third biggest-selling single in the US after "No, No, No" and "Bills, Bills, Bills" and was also their third gold RIAA certified single.