In early October 1944, Landis checked into St. Luke's Hospital in Chicago, where his wife Winifred had been hospitalized, with a severe cold. While in the hospital, he had a heart attack, causing him to miss the World Series for the first time in his commissionership. He remained fully alert, and as usual signed the World Series share checks to players. His contract was due to expire in January 1946; on November 17, 1944, baseball's owners voted him another seven-year term. However, on November 25, he died surrounded by family, five days after his 78th birthday. His longtime assistant, Leslie O'Connor, wept as he read the announcement for the press. Landis is buried at Oak Woods Cemetery in Chicago.