Chemical control can be difficult due to resistance development to some fungicides. Also there are few fungicidal modes of action that are effective. This includes the formerly successful metalaxyl, which is now widely ineffective due to resistance exhibited in the pathogen. Mefenoxam is another fungicide that pink rot pathogens have shown resistance against. However, research has shown that a combination of mefenoxam and oxathiapiprolin has demonstrated effectiveness on suppressing pink rot. There have been studies done on phosphorous acid (Phostrol) as a systemic and contact fungicide against pink rot, but the exact mode of action has not yet been determined. Fluopicolide, part of the benzamide class of fungicides, has been shown to be effective at reducing pink rot on field scales. There has not yet been cross-resistance between fluopicolide and mefenoxam, meaning these fungicides can be used rotationally to minimize the development of resistance.