Many studies in neurolinguistics take advantage of anomalies or "violations" of syntactic or semantic rules in experimental stimuli, and analyzing the brain responses elicited when a subject encounters these violations. For example, sentences beginning with phrases such as *"the garden was on the worked", which violates an English phrase structure rule, often elicit a brain response called the early left anterior negativity (ELAN). Violation techniques have been in use since at least 1980, when Kutas and Hillyard first reported ERP evidence that semantic violations elicited an N400 effect. Using similar methods, in 1992, Lee Osterhout first reported the P600 response to syntactic anomalies. Violation designs have also been used for hemodynamic studies (fMRI and PET): Embick and colleagues, for example, used grammatical and spelling violations to investigate the location of syntactic processing in the brain using fMRI. Another common use of violation designs is to combine two kinds of violations in the same sentence and thus make predictions about how different language processes interact with one another; this type of crossing-violation study has been used extensively to investigate how syntactic and semantic processes interact while people read or hear sentences.