He did work towards the anti-poverty and minimum needs programme. Other areas of his work were agriculture and cottage industry, rural health and rural education. Deshmukh assumed chairmanship of the institute after leaving politics and devoted all his time to building up the institute. He was also instrumental in carrying out social restructuring programme in over 500 villages of both Uttar Pradesh and Madhya Pradesh states of India. He also published the journal "Manthan" (introspection) which was edited by K.R. Malkani for many years.