On 19 October 2017, Meyler was announced as the manager of the Cork senior hurling team for a two-year term after the stepping down of Kingston. His first match in charge was a 2-23 to 1-21 loss to Limerick in the pre-season Munster League. Cork later went undefeated in the new Munster Championship round robin. Meyler guided the team to their second successive Munster final, where they defeated Clare on 1 July 2018 to win the title by 2-24 to 1-19.