Ralph Klein grew up in a working-class part of Calgary and dropped out of high school in grade 11, joined the Royal Canadian Air Force reserves, then completed high school later in life. Klein's time in the Air Force was limited, returning home a year later shortly after his 18th birthday. Klein attended Calgary Business College studying accounting and business administration, and later served as a teacher and principal of the College. He later studied at Athabasca University. Following his role at the Calgary Business College, Klein took a position as a public relations official at the Southern Alberta district of the Red Cross and United Way's offices in Calgary from 1963 to 1969.