In 1964, Joseph "Joe Bananas" Bonanno, the head of the Bonanno crime family, and Joseph Magliocco, the new boss of the Profaci crime family, conspired to kill Gambino and his allies on the Commission. However, the man entrusted with the job, Joseph Colombo, instead revealed the plot to Gambino. The Commission, led by Gambino, forced Magliocco to resign and hand over his family to Colombo, while Bonanno fled New York. Gambino then became the most powerful leader of the "Five Families".