In 2005, Ito was chosen to portray Reira Serizawa, the vocalist for rock band Trapnest in the film adaptation of Ai Yazawa's popular manga series "Nana". She released her debut single, "Endless Story", under the name "Reira Starring Yuna Ito"; the song was used as one of the theme songs for the film. "Endless Story" debuted on the Oricon chart at the #2 position. Following the release of "Endless Story" was her second single, "Faith/Pureyes" (2006), which debuted at #6 on the charts.