Lee began her career on Broadway in "Vintage 60" (1960) and "How to Succeed in Business Without Really Trying" (1961). She made her movie debut in the film version of the latter in 1967. Her other film appearances include the Disney film "The Love Bug" (1968) , "The Comic" (1969) and "Along Came Polly" (2004). She was nominated for the Tony Award for Best Actress in a Musical in 1974 for "Seesaw", and for the Tony Award for Best Featured Actress in a Play in 2001 for "The Tale of the Allergist's Wife". She also played the title role in the 1998 TV film "Scandalous Me: The Jacqueline Susann Story", and Madame Morrible in the Broadway musical "Wicked" in 2015.