The dentate contains anatomically separate and functionally distinct motor and nonmotor domains (dorsal and ventral, respectively), and projections are organized from the dentate nucleus to distinct areas in the ventrolateral thalamus. In addition, the dorsal parts of the dentate project to the primary motor and premotor areas of the cerebral cortex, while the ventral parts of the dentate project to prefrontal and posterior parietal areas of the cerebral cortex. The motor and nonmotor domains make up approximately 50–60 percent and 20 percent, respectively, of the dentate. It is estimated that the human dentate proportions are comparable. All cerebral cortical areas that are targeted by the dentate project back on the cerebellum via efferents to Pontine nuclei, and cortical areas that do not project onto the cerebellum are not targets of dentate output.