New York State Route 205 (NY 205) is a north–south state highway in central Otsego County, New York, in the United States. It extends from Interstate 88 (I-88) at exit 13 near the city of Oneonta to a junction with NY 28 and NY 80 in the town of Otsego. The latter junction also marks the east end of a overlap between NY 205 and NY 80, from where NY 80 heads southeast to follow NY 28 to Cooperstown. NY 205 is a two-lane highway for its entire length and passes through the towns of Oneonta, Laurens and Hartwick.