Paxinou made several appearances on the Broadway stage and television as well. She played the lead in Ibsen's "Hedda Gabler" for 12 performances at New York City's Longacre Theatre, opening on 28 June 1942. She also played the principal role in the first production in English of Federico Garcia Lorca's "The House of Bernarda Alba", at the ANTA Playhouse in New York in 1951, and a BBC television production of Lorca's "Blood Wedding" ("Bodas de sangre"), broadcast on 2 June 1959.