From 1919 through 1938, she amassed a 398–35 (91.9%) W/L match record, including a winning streak of at least 158 matches, during which she did not lose a set. She was the first American woman to win the French Championships and in 1928 became the first tennis player, male or female, to win three Grand Slam tournament or Majors in one calendar year. During the 17-year period from 1922 through 1938, Wills entered 24 Grand Slam singles events, winning 19, finishing runner-up three times, and defaulting twice as a result of her appendectomy. Wills won 31 Grand Slam tournament titles (singles, women's doubles, and mixed doubles), including seven singles titles at the U.S. Championships, eight singles titles at Wimbledon, and four singles titles at the French Championships. Excluding her defaults at the French Championships and Wimbledon in 1926, she reached the final of every Grand Slam singles event she competed in. She never played at the Australian Championships.