She started her stage career in Greece in 1928 and was one of the founding members of the National Theatre of Greece in 1932. The outbreak of World War II found her in the United Kingdom and she later moved to the United States, where she made her film debut in "For Whom the Bell Tolls" (1943) and won the Academy Award for Best Supporting Actress and the Golden Globe Award for Best Supporting Actress. She appeared in a few more Hollywood films, before returning to Greece in the early 1950s. She became a naturalized citizen of the United States in 1951. She then focused on her stage career and appeared in a number of European films including "Rocco and His Brothers" (1960).