By the end of 1942, there were 199 aircraft in service, 88 of which were operational. Maritime reconnaissance had at that time 290 aircraft in total. By September 1943, there were still 240 aircraft assigned to maritime reconnaissance: only 84 were Z.501s, in three squadrons, and another 11 (mixed), out of 20 in total. Only around 40 aircraft were operational. Total production, 218 by CANT and 236 by Aeronautica Sicula, but 12 incomplete aircraft were captured after the invasion of Sicily. Later, Aeronautica Sicula repaired many of the ICAF aircraft. Some modifications were adopted during production, such as the removal of the nose machine gun; it was replaced by an enclosed fairing.