The Quadi and Marcomanni destroyed the main Roman town in the area, Opitergium (modern Oderzo) in AD 166–168. This part of Roman Italy was again overrun in the early 5th century by the Visigoths and by Attila of the Huns who sacked Altinum (a town on the mainland coast of the lagoon of Venice) in 452. The last and most enduring immigration into the north of the Italian peninsula, that of the Lombards in 568, was the most devastating for the north-eastern region, Venetia (modern Veneto and Friuli). It also confined the Italian territories of the Eastern Roman Empire to part of central Italy and the coastal lagoons of Venetia, known as the Exarchate of Ravenna. Around this time, Cassiodorus mentions the "incolae lacunae" ("lagoon dwellers"), their fishing and their saltworks and how they strengthened the islands with embankments. The former Opitergium region had finally begun to recover from the various invasions when it was destroyed again, this time for good, by the Lombards led by Grimoald in 667.