In February to March 2010, Smillie appeared on stage in "Hormonal Housewives", a new comedy written by Julie Coombe and John MacIsaac. Appearing alongside Smillie were the co-writer Julie Coombe and Shonagh Price. The comedy portrayed three women juggling a career, childcare and being a housewife. The play begins with the three women getting ready for a night out and then moves into a series of self-contained sketches. The finale features a medley of music by Kylie Minogue, Madonna and Cher. Smillie takes the part of Madonna, dancing and miming to the track "Holiday", dressed in a pastiche outfit based on the Jean Paul Gaultier-designed conical bra corset, from the singer's 1990 Blond Ambition tour. Smillie took the play on a three-week tour of Scotland performing at theatres in Aberdeen, Dundee, Edinburgh, Glasgow and Inverness.