The Colt .45s started their inaugural season on April 10, 1962, against the Chicago Cubs with Harry Craft as the Colt .45s' manager. Bob Aspromonte scored the first run for the Colt .45s on an Al Spangler triple in the first inning. They started the season with a three-game sweep of the Cubs but eventually finished eighth among the National League's ten teams. The team's best pitcher, Richard "Turk" Farrell, lost 20 games despite an ERA of 3.02. A starter for the Colt .45s, Farrell was primarily a relief pitcher prior to playing for Houston. He was selected to both All-Star Games in 1962.