Rookie Phillies pitcher Marty Bystrom was sent out by Philadelphia manager Dallas Green to face veteran Nolan Ryan in Game Five. The rookie gave up a run in the first inning, then held the Astros at bay until the sixth inning. An Astros lead was lost when Bob Boone hit a two-out single in the second, but the Astros tied the game in the sixth with an Alan Ashby single scoring Denny Walling. Houston took a 5–2 lead in the seventh, however the Phillies came back with five runs in the inning. The Astros came back against Tug McGraw with four singles and two two-out runs. Now in extra innings, Garry Maddox doubled in Del Unser with one out to give the Phillies an 8–7 lead. The Astros failed to score in the bottom of the tenth.