Enríquez also acquired the local rights of the Royal Guinea Company and later the Asiento, organizations dedicated to slave trading which were authorized to do so by Spain. His actions placed him at odds with several influential members of San Juan's society. To counter this, Enríquez supported any new governor by offering his services and providing other help. However, all but José Antonio Mendizábal unsuccessfully tried to revoke his privateering contract, often finding themselves in trouble when he responded by using his resources. The most notable example was Juan de Ribera, who Enríquez managed to remove from the office of governor after an arduous conflict by employing his influence. He also pursued the favor of the bishops appointed to San Juan, earning the support of Pedro de la Concepción Urtiaga and Fernando de Valbidia, but failing to earn the trust of Lorenzo Pizarro. Enríquez's influence extended to several other systems, including the courts and military. He owned 300 slaves and his fortune, at the time, was among the largest in the Americas. Throughout his career, Enríquez was persecuted by the Spanish elite in the island and jailed on various occasions. At the peak of his success, he was able to employ his influence to have governor Danío Granados prosecuted and jailed. However, as international politics evolved, his influence dwindled. By the time that Matías de Abadía became governor, Enríquez was unable to accomplish his removal from office. He was charged with smuggling and stripped of all his power and wealth by the government. Enríquez fled and took refuge in the Catholic Church, which he regularly attended. By being generous with his donations to the bishopric, he had gained allies who would protect him throughout the years. The charges of smuggling made by the Spanish government were eventually dropped, but Enríquez chose to remain in the convent where he died a pauper.