In a Grey Cup rematch to kick off the 2010 CFL season, Durant and the Roughriders staged a second half comeback to defeat the Alouettes in overtime. Durant threw five touchdown passes and picked up 478 passing yards during the game. For his efforts, he was named the CFL's Offensive Player of the Week. At the halfway point of the season, Durant had thrown 11 touchdown passes and 14 interceptions, while rushing for another five touchdowns. The CFL named Durant Offensive Player of the Month for September after a month where he passed for 1387 yards and five touchdowns. After Game 17 versus the BC Lions, Durant became only the second Roughrider quarterback to throw for over 5,000 yards in a season, with the first being former head coach Kent Austin. Durant was selected as the Roughriders' nominee for the CFL Most Outstanding Player Award.