Thandiswa has performed all over the world at venues, including at the 2010 FIFA World Cup Opening Ceremony, The Apollo in New York, WOMEX, the Cannes Film Festival, Midem, the Hackney Empire, Africa Brazil Festival, FESPACO Film Festival, BBC World Music Awards and many Mandela 46664 concerts. She has several noteworthy collaborations. For instance, she collaborated on two songs with US musician Meshell Ndegeocello on her album "The World Has Made Me the Man of My Dreams", which was nominated for a Grammy in 2007. At home in South Africa, Thandiswa has collaborated with illustrious musicians including Hugh Masekela, Stimela, the late Busi Mhlongo. Together with the rock band BLK JKS, Thandiswa performed as 'King Tha' vs. BLK JKS at the 2017 Afropunk Festival Johannesburg.