Archaeal Genetics is the study of genes that consist of single nucleus-free cells. Archaea have a single, circular chromosomes that contain multiple origins of replication for initiation of DNA synthesis. DNA replication of Archaea involves similar processes including initiation, elongation, and termination. The primase used to synthesize a RNA primer varies than in eukaryotes. The primase by archaea is highly derived version of RNA recognition motif(RRM). Archaea come from Gram positive bacteria, which both have a single lipid bilayer, which are resistant to antibiotics. Archaea are similar to mitochondria in eukaryotes in that they release energy as adenosine triphosphate (ATP) through the chemical reaction called metabolism. Some archaea known as phototrophic archaea use the sun’s energy to produce ATP. ATP synthase is used as photophosphorylation to convert chemicals into ATP.