Callie and Arizona have a five-year relationship, ultimately marrying in season 7 and divorcing in season 11. Callie starts a new relationship with Penny Blake and leaves to go to New York with her in the season 12 finale. Shonda Rhimes spoke on Ramirez's abrupt departure, saying, "This one was different because it wasn't a big planned thing. I had a different plan going and when Sara came in and said, 'I really need to take this break,' I was lucky that we'd shot the end of the season with her going to New York."