The school was opened in 1963 and has had over 15,000 graduates. Since 1966, the school has been accredited by AdvancED, formerly North Central Association Commission on Accreditation and School Improvement. Southside was ranked 625th in Newsweek's Top 1,300 High Schools in the U.S. in 2008. In 2008, Southside was the recipient of "Best Practice School" by Arkansas Governor Mike Beebe. For the 2007-2008 school year, Southside received the Siemen's Award for Advanced Placement exam scores. Southside was in Newsweek's Top 1,000 High Schools in America for the 2009-2010 school year.