Her next role was in the light-hearted comedy "Little Nicky" (2000), alongside Adam Sandler. Despite being a box office hit, the film received negative reviews, although Roger Ebert called it Sandler's best film to date. Following this, she starred in French-American comedy drama "Human Nature" (2001), written by Charlie Kaufman and directed by Michel Gondry. The film was met with mixed reviews and was screened out of competition at the 2001 Cannes Film Festival. Roger Ebert, in a three-star (out of a possible four) review, lauded the film's "screwball charm". The following year, she appeared in the small-scale mystery film "The Badge", playing the widowed victim of a murdered transsexual woman. In 2003, she portrayed the controversial pornographic film star Linda Lovelace in the little known "Deeper than Deep", which was followed with the more family orientated Disney produced "Holes", as Kissin' Kate Barlow. Based on the 1998 novel of the same title by Louis Sachar, "Holes" grossed $16,300,155 in its opening weekend, making #2 at the box office, behind "Anger Management"s second weekend. "Holes" would go on to gross a domestic total of $67,406,173 and an additional $4 million in international revenue, totaling $71,406,573 at the box office against a $20 million budget, making the film a moderate financial success. Arquette's next film, "Tiptoes", was released straight-to-DVD in the United States, despite a screening at the Sundance Film Festival.