Following a short-lived relationship with physiotherapist Justin Fuller (Ben Richards), Donna moves on to date hospital manager Bradley Hume (Scott Adkins). Their relationship is terminated by the discovery that Bradley has been running a pharmaceutical scam, resulting in the death of one of Donna's patients due to a morphine overdose. After entering into a scratchcard syndicate at work, Donna wins £20,000. She refuses to share her winnings with the others and resigns from her job, making plans to travel to Australia. On her last day, a patient with bi-polar disorder steals and re-distributes her money. Donna misses her flight, and is forced to remain in Holby. She goes on to begin an affair with consultant general surgeon Michael Spence (Hari Dhillon), despite the fact he is married. When Michael's wife Annalese (Anna-Louise Plowman) begins working at the hospital as a locum anaesthetist, she suspects that Michael has been unfaithful to her and confronts Donna, who confesses the affair and apologises profusely.