When English colonists came to America, Berlin was first granted on December 31, 1771, by Colonial Governor John Wentworth, as "Maynesborough" after Sir William Mayne. But the grantees did not take up their claims, which disappeared with the Revolution. In 1802, Seth Eames and Gideon Tirrell were sent by the descendants of Mayne to explore and mark lots for settlers, and still no one came. Maynesborough was settled in 1823–1824 by William Sessions and his nephew, Cyrus Wheeler. Both men were from Gilead, Maine. Farming was the first industry. With 65 inhabitants in 1829, the New England town was reincorporated on July 1 as Berlin with the help of Cyrus' father, Thomas Wheeler.