North of Gladewater, US 271 passes through Gilmer, where there are junctions with SH 300 and SH 154. There is also another concurrency (only 1.5 miles) with SH 155 which then veers to the northeast toward Linden. North of Gilmer is Pittsburg, where US 271 intersects with SH 11. Then the highway crosses Big Cypress Creek just below the dam that forms Lake Bob Sandlin. In Mount Pleasant, there are junctions with SH 49 and US 67 and then the interchange with Interstate 30. Beyond IH 30 are the small towns of Talco, Bogata (junction with SH 37), Deport, and Pattonville.