Murphy started his career in television with the teen comedy series "Popular", which he co-created with Gina Matthews. The series premiered on The WB on September 29, 1999 and ran for two seasons, ending in 2001. During the time, his production company Ryan Murphy Productions signed a deal with the Warners. He then created the FX drama series "Nip/Tuck", which premiered on July 18, 2003. In 2004, Murphy earned his first Primetime Emmy Award nomination for Outstanding Directing for a Drama Series. Murphy took the show's signature line, "Tell me what you don't like about yourself," from a plastic surgeon he met when he was a journalist researching an undercover story on plastic surgery in Beverly Hills. The series ended after six seasons in 2010.