Rezaï started playing for France in 2006. For the second year in a row, she lost in the qualifying rounds of the Australian Open. However, her French Open run was more successful. She struggled through to the third round of the tournament, defeating Ai Sugiyama of Japan along the way. She fell to Nicole Vaidišová, in a hard-fought three-setter. Her Wimbledon dreams were also put on hold as she fell in the first round of qualifying. At the US Open, she reached the fourth round, her career best Grand Slam singles result. She also competed on the ITF Circuit throughout the year, reaching the final of two tournaments, as well as winning one in the later part of the year on the hard courts of France.