Following a 13–3 season in 2000 which ended in a playoff loss to the Baltimore Ravens, McNair put together his most productive year as a pro in 2001. In 2001, McNair registered career passing highs in yards (3,350), completions (264), touchdowns (21) and quarterback rating (90.2). He was also the team's most effective rusher, tying George for the club lead with five scores. Named to the Pro Bowl for the first time, McNair sat out the game due to a shoulder injury.