In 1908, Lane moved to San Francisco, California, where she worked as a telegrapher at the Fairmont Hotel. In March 1909, Lane married salesman, promoter and occasional newspaperman Claire Gillette Lane. Evidence exists that suggests the Lanes had met back in Kansas City and Lane's diary hints that she moved to San Francisco to join her future husband. Shortly after they wed, Lane quit her job with Western Union and the couple embarked on travels across the United States to promote various schemes. Lane soon became pregnant. While staying in Salt Lake City the following November, Lane gave birth to a premature, stillborn son, according to public records. Subsequent surgery in Kansas City likely left her unable to bear children. The topic is mentioned only briefly in a handful of existing letters written by Lane years after the infant's death in order to express sympathy and understanding to close friends who were also dealing with the loss of a child.