In 1894, the school was renamed to honor the distinguished poet James Russell Lowell, chiefly by Pelham W. Ames, a member of the school board and ardent admirer of James Russell Lowell. The school relocated in January 1913 to an entire block on Hayes Street between Ashbury and Masonic. Lowell remained there for 50 years and established its position as the city's college preparatory high school. In 1952, the school sought a new location near Lake Merced and moved there (its present address) in 1962.