The interior of the Atalanta featured several novel features. The cockpit, which was crewed by a pair of pilots and a radio operator, was unusually large; immediately behind it was a compartment intended to accommodate up to one tonne of air mail. A luggage hold and a galley was positioned further behind that. The main cabin was designed to adjustable, readily permitting operators to change the passenger-to-freight ratio. Imperial Airways initially opted to configure it with nine seats, arranged in alternating pairs and standalone, all of which with tables. Particular attention was paid to the air conditioning systems due to the type's envisioned frequent use within relatively hot climates. Later on, Imperial Airways adopted a more profitable eleven seat configuration for its African route.