On November 12, 2016 he fought Cuban boxer Luis Ortiz in Monaco. Despite claiming to have a perfect camp, the bout was largely uneventful and disappointing. Scott was on the backfoot for most of the fight and seemed completely unwilling to engage with Ortiz. British commentator Adam Smith lamented the bout as "the worst I have seen in many years". Matchroom promoter Eddie Hearn was also visibly disappointed after the bout and claimed that "Scott didn`t do us any favours tonight". The official scorecards were 120–105, 120–106, and 119–106 all in favor of Ortiz.