Northward, US 271 is a two-lane road. It goes under the turnpike without an interchange before entering Antlers, where there is a concurrency with SH 3 through town. Leaving Antlers, US 271 crosses the Kiamichi River. The road to Clayton is sinuous and scenic, passing through hilly woodlands. The route passes through the communities of Snow and Finley, followed by the western terminus of SH 144 before passing the Clayton Lake State Park and then crossing the Kiamichi again. There are weight limits of 15 tons (depending on vehicle length) posted between SH 144 and Clayton.