At the beginning of the 1st millennium, there was significant trade in coral between the Mediterranean and India, where it was highly prized as a substance believed to be endowed with mysterious sacred properties. Pliny the Elder remarks that, before the great demand from India, the Gauls used it for the ornamentation of their weapons and helmets; but by this period, so great was the Eastern demand, that it was very rarely seen even in the regions which produced it. Among the Romans, branches of coral were hung around children's necks to preserve them from danger from the outside, and the substance had many medicinal virtues attributed to it. The belief in coral's potency as a charm continued throughout the Middle Ages and early in 20th century Italy it was worn as a protection from the evil eye, and by women as a cure for infertility.