While in the position of foreign minister, Migiro chaired the Council of Ministers' meetings of the International Conference of the Great Lakes Region and the Southern African Development Community(SADC) Ministerial Committee of the Organ on Politics, Defense and Security Cooperation. She coordinated SADC assistance to the elections in the Democratic Republic of the Congo (DRC), Zambia and Madagascar. She also served as President of the United Nations Security Council during its open debate on peace, security and development in the Great Lakes Region.