In Week 1, Brees threw for more than 400 yards for a record 16th time in his career, but the Tampa Bay Buccaneers won 48–40. In Week 3, against the Atlanta Falcons, Brees broke Brett Favre's record for career pass completions in the second quarter with his 6,301st career completion. In that game, a 43–37 overtime Saints victory, Brees threw for 396 yards and three touchdowns, and also ran for two more scores, including the game-winner in overtime, earning him NFC Offensive Player of the Week. In Week 5, on "Monday Night Football" against the Washington Redskins, Brees surpassed Peyton Manning for the NFL's all-time passing yardage record with a 62-yard touchdown pass to Tre'Quan Smith late in the second quarter. He went on to complete 26 of 29 passes, setting a then career-high 89.66 single-game completion percentage, for 363 yards and three touchdowns in the 43–19 victory, earning him NFC Offensive Player of the Week for the second time in three weeks. Following a bye week, Brees finally claimed his first career victory against the Baltimore Ravens with a score of 24–23, making him the third quarterback in NFL history to beat all 32 teams, joining Peyton Manning and Brett Favre. During this game, Brees also became the fourth quarterback in NFL history, along with Manning, Favre, and Tom Brady, to reach 500 career touchdown passes when he threw a 1-yard touchdown to Benjamin Watson. After a season-low 120 yards and his first interception of the season in a win over the Minnesota Vikings, Brees logged 346 yards, four touchdowns, and zero interceptions to hand the Rams their first loss of the season in Week 9. In a Week 10 matchup against the Cincinnati Bengals, Brees passed Brett Favre for second in career passing touchdowns with a 17-yard touchdown to Michael Thomas in a 51–14 victory. Brees was named the NFC Offensive Player of the Month for his performance during the month of November.