Upon leaving Dover, DE 15 continues through a mix of farmland and woodland with some residential areas, turning southwest onto West Denneys Road and then north onto Kenton Road. The road crosses Fork Branch and curves to the north-northwest, crossing Pearsons Corner Road before reaching an intersection with DE 42 in Moores Corner. At this point, DE 15 turns west to form a concurrency with DE 42 on Seven Hickories Road. In Seven Hickories, DE 15 splits from DE 42 by heading north on Brenford Road. The route splits from Brenford Road and continues northwest on Mount Friendship Road, crossing the Leipsic River before reaching an intersection with DE 300. Here, DE 15 turns northeast for a brief concurrency with DE 300 on Wheatleys Pond Road before turning northwest on Alley Corner Road. The road crosses Mill Creek and an abandoned railroad line before it comes to an intersection with DE 6. At this point, DE 15 turns east to form a concurrency with DE 6 on Millington Road. On the western edge of the town of Clayton, DE 15 splits from DE 6 by heading northeast on Duck Creek Road, passing through residential areas with some industry. The road curves to the north and leaves Clayton.