From 2008 to 2018 Vine presented "Points of View", taking over from Sir Terry Wogan. On 6 October 2008, he started hosting the former BBC Two quiz show "Eggheads" while the spin-off show, "Are You an Egghead?", was presented by the regular host, Dermot Murnaghan. Once the spin-off show had finished, Vine continued to host the second half of each series, with Murnaghan hosting the first half. In Series 16, it was announced that Vine had become the sole presenter. As of 2014, Vine also hosted the spin-off series "Revenge of the Egghead". The series ran for a 6-week period, between 24 February and 4 April 2014. On 12 March 2021, it was announced that after 18 years at the BBC, the programme would be moving to Channel 5, and Vine was to continue as host of the show.