In 1998, Loken starred in ' as Taja. She played the gynoid T-X (Terminatrix) in the 2003 movie '. In 2004, she appeared in a German television movie, "" (also known as "Dark Kingdom: The Dragon King" or "Sword of Xanten"), which aired as a two-part miniseries and set a ratings record. She starred as the leading character in the 2006 film version of the video game "BloodRayne", and appeared in director Uwe Boll's film version of the video game "Dungeon Siege", called "In the Name of the King".