In 1961, on CBS's "The Andy Griffith Show", Clyde played Frank Myers, an eccentric old man whom the town tries to evict in the episode "Mayberry Goes Bankrupt". Clyde portrayed Poney Thompson in "Snakebite" in 1958 and Henry Squires in "Durham Bull" in 1962 on CBS's long-running western series "Gunsmoke". Clyde appeared as Grandpa Jim Anderson in five episodes of the 1964–65 ABC military comedy "No Time for Sergeants", starring Sammy Jackson. The series was inspired by an earlier Andy Griffith film of the same name.