Then, in the 1964 World Series, Warwick was called on to pinch hit five times by manager Johnny Keane. He reached base four times in his first four appearances. His sixth-inning pinch single in Game 1 off Al Downing drove home the go-ahead run in the Cardinals' 9–5 triumph. He also singled and scored a run in Game 2 against Mel Stottlemyre, drew a base on balls from Jim Bouton in Game 3 and singled again off Downing in Game 4, to spark a rally capped by Ken Boyer's grand slam home run in a 4–3 Cardinal win. He fouled out off Bouton in Game 6 to complete a Series in which he batted .750 with an .800 on-base percentage, two runs scored and an RBI.