Lederer has always been a guest or supporting actress on programmes devised by or starring her alternative comedy contemporaries and as such has made a good, consistent career. She was one of the first female stand-up comedians to feature on ITV's "Saturday Night Live" with her own stand up set. She then took part in "The Vagina Monologues" on the West End stage. Following ‘The House of Blue leaves’ at the Lilian Baylis Theatre with the late Denis Quilley. ‘Having a Ball’ by Alan Bleasdale at the Comedy Theatre, she then appeared in "The Killing of Sister George" at the Arts Theatres and "Calendar Girls" with Kelly Brook at the Wyndham's Theatre.