"Pick You Up" was the first release by Powderfinger to receive significant radio airplay. Whilst "Reap What You Sow", off their previous EP; "Transfusion", had achieved some success, "Pick You Up" was the first to be played regularly nationwide. Guitarist Darren Middleton said the band were "stoked" with the song's success, saying that "it's great for us because hopefully it'll give us a few more opportunities to do what we want to do." Middleton attributed part of the success of "Pick You Up" to Tim Whitten, producer of the song and "Double Allergic", describing Whitten as "what a band looks for in a producer/engineer".