Keedy was signed by then Lancashire coach David Lloyd in a motorway service station. Although it took time for him to become a leading light of the Lancashire attack, he was awarded his county cap in 2000. It was in 2003 that Keedy first started to impress observers, taking sixty wickets in the County Championship as Lancashire narrowly missed out on their first Championship title since 1934 to Sussex. Since then he has remained on the periphery of England selection. He was considered unlucky not to win a place to tour Sri Lanka in 2003-4. The selectors chose Glamorgan's Robert Croft instead.