US 60 had its beginnings in the Midland Trail, an auto trail organized in 1912 by residents of Grand Junction, Colorado. The next year, this route was considered but rejected for the Lincoln Highway, after which the Midland Trail Association laid out and marked its own transcontinental highway, eventually connecting Newport News, Virginia with Los Angeles, California. When the Joint Board on Interstate Highways published its preliminary plan for a system of interstate routes in 1925, the Midland Trail was split among many numbers, including 52, 62, 150, 50, and 40. East of Louisville, where it would become US 60, it was assigned parts of 52 and 62. Route 52 began at Newport News and followed the Midland Trail to Richmond, but took a more southerly route to Lexington, Virginia. The trail was used again through West Virginia to Huntington, where Route 52 split to the northwest. Route 62 began at Ashland, Kentucky (near Huntington) and followed the Midland Trail across northeastern Kentucky to Louisville, where the trail crossed the Ohio River and became Route 150. Route 62 continued southwest along the south bank of the Ohio River to Wickliffe in western Kentucky, and then crossed the Mississippi River at the Ohio's mouth. The final portion of Route 62 crossed southern Missouri to Springfield on an existing main highway that had been numbered 16 by the state.