The Spanish colonial settlement of Villa de San Agustin de Laredo was founded in 1755 by Don Tomás Sánchez Barrera while the area was part of the Nuevo Santander region in the Spanish colony of New Spain. Villa de San Agustin de Laredo was named after Laredo, Cantabria, Spain and in honor of Saint Augustine of Hippo. In 1840, Laredo was the capital of the independent Republic of the Rio Grande, set up in opposition to Antonio López de Santa Anna; it was brought back into Mexico by military force.