The Polish architect Władysław Horodecki originally constructed the House with Chimaeras for use as his own upmarket apartment building during the period of 1901–1902. However, as the years went by, Horodecki eventually had to sell the building due to financial troubles, after which it changed ownership numerous times before finally being occupied by an official Communist Party polyclinic until the early 2000s. When the building was vacated, its interior and exterior decor were fully reconstructed and restored according to Horodecki's original plans.