Anglezarke was dependent on the barony of Manchester. Albert Grelley gave two oxgangs of land to Robert de Lathom for an annual rent of 3 shillings. Between 1230 and 1264 Robert son of Richard, Lord of Lathom granted his land known as 'Swinlehehurst' to Burscough Priory. In 1339 Edward III granted free warren in Anglezarke to Thomas de Lathum. In 1298 Sir Robert Fitzhenry, Lord of Lathom gifted land as perpetual alms to Burscough Priory who earned income from rents, a confirmation charter was granted by Henry V in 1422. The Knights Hospitallers held land at Anglezarke. In 1406 John of Stanley Kt granted Anglezarke and its commons held in feoffment of William of Fulthorp Kt to Edward of Lathom senior in exchange for 1000 marks.