Once again, Kendrick was not a member of the opening day starting rotation, as Blanton and Vance Worley rounded out the final two spots after Hamels, Halladay, and Lee. However, once again, he joined the rotation due to injury, this season to Worley. He was a member of the rotation from the end of April to the beginning of July, in a relief role until the beginning of August, and then in the rotation for the remainder of the season. Ultimately, Kendrick started 25 games of a career-high 37 appearances. He was especially strong after the all-star game, posting a 3.15 ERA and nine wins, the latter of which was tied for first in the National League. He also continued his success against NL East teams, posting a 3.25 ERA against them. Though he had much success, he remained inconsistent, playing "the role Dr. Jekyll and Mr. Hyde personified" – in 17 of his starts, he allowed two or fewer earned runs, and posted a combined 1.73 ERA in those starts, while in the eight starts during which he surrendered more than two earned runs, he posted a 10.40 ERA.