In 2005, after his wife Barbara was diagnosed with Alzheimer's disease, Broyles became an outspoken advocate for Alzheimer's awareness and established the Frank and Barbara Broyles Foundation to support caregivers of Alzheimer's patients. With the assistance of the University of Arkansas Medical Sciences, he published and distributed 100,000 free copies of a book titled "Coach Broyles' Playbook for Alzheimer's Caregivers" to pharmacies throughout the state of Arkansas. In 2007 and again in 2009, Broyles successfully raised funds to distribute 500,000 copies of the book nationally, plus 100,000 copies in Spanish. Since then, the book has been translated into 11 different languages and distributed digitally worldwide. Broyles himself would eventually succumb to complications of the same disease on August 14, 2017.