After April's failed wedding to Matthew, Callie and Arizona bought a house together, a fresh start, away from the memories of their apartment. They later decided to try again for a second child. However, a trip to the OB/GYN led to the discovery that Callie had developed adhesions in her uterus in the years since Sofia's birth, meaning she could not carry any more babies. After talking about it, the couple agreed to postpone their dream to have another baby until they're on more solid footing as a couple.