She founded Down There Press, a publisher of sex-related books, in 1975. In 1977, she opened Good Vibrations, the second feminist sex toy business in the United States (the first having been Eve's Garden in New York City, which was founded by Dell Williams in 1974). Prior to her opening Good Vibrations, she was hired at the University of California, San Francisco to screen candidates who had difficulties achieving orgasm. This study influenced her business model for Good Vibrations. Lynn Comella wrote that Blank turned "her small vibrator shop into a sexual resource center for anyone who might wander in. She felt that talking about sex should be as casual as talking about the weather; she also believed that sexual information was a birthright and that no one should be made to feel ashamed or embarrassed for wanting more pleasure in their life."