The Parish Church of St Mary the Virgin is a Grade I listed building and was at the centre of the ancient ecclesiastical parish of Prestwich-cum-Oldham that extended beyond the township boundaries. It is known that it had a rector by 1200. Parts of the present building date from around 1500, although extensions were made at the end of the 19th century. For a time in the 19th century, the church was referred to as St Bartholomew's. The church wakes were traditionally held around St Bartholomew's Day. The living of Prestwich was suspended by the Diocese of Manchester in 2002. A priest-in-charge, The Revd. Bryan Hackett, residing in the rectory, was appointed.