Two days after the events of the first film, a traumatized and blood-covered Sarah escapes the cave system with no memory of what happened. She is taken to a hospital, where the doctor finds that some of the blood on her is of the same blood type as Juno, one of her missing friends. Sheriff Vaines and his deputy Rios bring along the amnesiac Sarah and three potholing cave specialists - Dan, Greg, and Cath - to find the missing women in the cave system. They are sent down via an old mine shaft operated by an old man, Ed.