Chicago Drive, largely signed as M-121, is a combination state trunkline highway and municipal street running from 8th Street in Holland to the intersection of Grandville and Clyde Park avenues at the border of Grand Rapids and Wyoming, approximately in length. Running eastward, Chicago Drive picks up the Business Loop I-196 designation east of US 31. The highway has the typical mix of industry and commercial properties for the area. At 112th Avenue, it turns northeasterly to run through Zeeland. The roadway changes names when it turns due east again, where it is named Main Avenue and Main Place, comprising the only section of the route not designated Chicago Drive.