In 2010, Ueto launched her third and fourth wedding dress collections, starred alongside Kin'ya Kitaōji in the Fuji TV drama "Zettai Reido", and made a cameo appearance in Shun Oguri's directorial debut, "Surely Someday". In August 2010, Ueto co-starred with Masaaki Uchino for the first time since "Ace o Nerae!" (2004) in her first NHK drama leading role, "Jūnensaki mo Kimi ni Koishite". In September 2010, Ueto portrayed blind singer-songwriter Satoko Tatemichi in the TV movie "Ai wa Mieru". Ueto next co-starred with Yutaka Takenouchi in her second Getsuku drama, "Nagareboshi". The drama was very well received by critics and audiences alike and was the second best rated of the fall season. Ueto was nominated for Best Supporting Actress at the Nikkan Sports Drama Grand Prix and won the Television Drama Academy Award for her role in "Nagareboshi". Boasting advertising contracts with 13 different companies, Ueto was crowned CM Queen for a second consecutive year, making it the fifth time she has held the title.