Wisher is remembered for many different roles in the British science fiction television series "Doctor Who". His contributions began with uncredited voice work in the Second Doctor serial "The Seeds of Death" (1969). The director of that story, Michael Ferguson, later asked Wisher to play reporter John Wakefield in the Third Doctor serial "The Ambassadors of Death" (1970). In the following season he appeared as Rex Farrel in "Terror of the Autons" (1971). During the later years of the Third Doctor era, Wisher acted as the villainous Commissioner Kalik in "Carnival of Monsters" (1973) and provided Dalek voices in "Frontier in Space" (1973), "Planet of the Daleks" (1973) and "Death to the Daleks" (1974).