The Church of Saint Francis, which has the traditional Latin cross plan, was probably founded in 1239 thanks to the nobleman Antonio Gizio, who donated his estate to the project. In the second half of the 14th century a new façade was constructed, but it was rebuilt in the 17th century except the top with a rose window. After years of decay, in 1689 they started an extensive restoration which changed the appearance of this church. At the end of the 19th century, the architect Torquato Scaraviglia added an external stairway and another intervention was commissioned by the noblewoman Theresa de Hortalis. The church has an hemispherical dome with "trompe-l'œil" paintings and ten chapels, whose improvements were financed by some of the most important and ancient families of Chieti.