Wells is renowned for his logistically complex sample-collecting expeditions in remote parts of the world. EurAsia98, which in 1998 took him and his team from London to the Altai Mountains on the Mongolian border, via an overland route through the Caucasus, Iran and the -stans of Central Asia, was sponsored by Land Rover. In 2005 he led a team of Genographic scientists on the first modern expedition to the Tibesti Mountains in northern Chad, and in 2006 he led a team to the Wakhan Corridor on the Tajik-Afghan border. His work has taken him to more than 100 countries.