In 2014, Harbour portrayed the recurring character of Dr. Reed Akley in the first season of the historical drama series "Manhattan". In 2015, Harbour was cast as Chief Jim Hopper in the Netflix science fiction horror series "Stranger Things". For his role in the series, Harbour has received nominations for the Primetime Emmy Award for Outstanding Supporting Actor in a Drama Series (2017 and 2018) and the Golden Globe Award for Best Supporting Actor – Series, Miniseries or Television Film (2018). Harbour has won a Screen Actors Guild Award for Outstanding Performance by an Ensemble in a Drama Series (2017) along with the rest of the cast.