Ager again led the Spartans in scoring in 2006, as he averaged 19.3 points per game as a senior. On November 22, 2005, at the Maui Invitational Tournament, Ager faced off against Gonzaga's Adam Morrison in one of the most thrilling battles of the year. Down by three with virtually no time remaining on the clock, Ager sank a three-point shot at the buzzer to send the game into overtime. Despite Ager's team-high 36 points, Gonzaga knocked off the Spartans in triple overtime 109–106. The next day Ager led the Spartans with 20 points to defeat Arizona 74–71 in overtime. Despite this, the Spartans did not live up to the expectations that analysts put on them. Once ranked No. 5 in the country, they received a No. 6 seed in the NCAA Tournament, where they fell to George Mason in the First Round. (George Mason would go on to the Final Four).