O'Bannon made his writing debut selling spec material to NBC's "Amazing Stories" (1985) and CBS's "The Twilight Zone" (1985), but first garnered critical attention for his film "Alien Nation" (1988) and its subsequent spinoff television show. His next notable achievement was his original series "seaQuest DSV" (1993) which ran for three seasons. O'Bannon's most critically acclaimed success was the space epic "Farscape" on the Sci-Fi Channel (1999–2003) which ran for four seasons and spun off into a mini-series as well as a comic book series. Since "Farscape", he's created the TV show "Defiance" (2013) and The CW's "Cult" (2013), the miniseries "The Triangle" (2005), as well as an uncredited rewrite on the pilot for "Warehouse 13" (2009). He has also served as Executive Producer and writer on "Constantine", "Revolution", "V", and "Evil" (on CBS) among others.