Chauvin's description of metathesis led Robert H. Grubbs and Richard R. Schrock to develop catalysts that carried out the reaction more efficiently. The three chemists' work has enabled manufacturers to make organic compounds, including some plastics and medicines, using less energy because the required reaction pressures and temperatures became lower, and using fewer harmful and expensive chemicals, and creating fewer contaminant reaction by-products and hazardous waste that must be extracted from the desired synthetic. It was for this process they were awarded with 2005 Chemistry Nobel Prize.