Upon graduating high school Tagame moved to Tokyo to study graphic design at Tama Art University against the wishes of his parents, who expected him to attend the University of Tokyo and become a banker. Throughout college he submitted gay erotic stories, illustrations, and manga to "Barazoku", "René", and other gay and BL magazines under a variety of pseudonyms, eventually settling on the pen name "Gengoroh Tagame"; both words are Japanese terms for different species of water bugs, which Tagame chose to differentiate himself from the "macho or romantic" pen names used by other gay Japanese artists. While on a student art tour of Europe, Tagame discovered the American leather magazine "Drummer" at a bookshop in London. The magazine featured homoerotic and fetishistic illustrations by western artists such as Tom of Finland, Rex, and Bill Ward, and would heavily influence Tagame's art. After graduating university he began to work as a commercial graphic designer and later art director, while continuing to write manga and prose fiction.