A popular setup from White to prevent Black's plan is the Voronezh Variation (named after the Russian city Voronezh, where the line was invented, by players such as Grigory Sanakoev). The Voronezh is defined by the opening sequence 1.e4 Nf6 2.e5 Nd5 3.d4 d6 4.c4 Nb6 5.exd6 cxd6 6.Nc3 g6 7.Be3 Bg7 8.Rc1 0-0 9.b3. White's setup delays so that Black has trouble developing pieces in a fashion that harasses White's pieces and assails the centre pawns; for instance there is no knight on f3 which can become a target after ...Bg4, and no bishop on d3 which may be a target after ...Nc6–e5. While 9...Nc6 is Black's most common reply according to ChessBase's database, after 10.d5 Ne5 Black's knight lacks a target, and will soon be chased out with f2–f4, and this line has scored very poorly for Black. The main line in the Voronezh, and the second most common reply, is 9...e5 10.dxe5 dxe5 11.Qxd8 Rxd8 12.c5 N6d7 (This retreat is forced since 12...Nd5?? loses the knight due to the 13.Rd1 pin) when Black must play carefully to unentangle and challenge the white pawn on c5. Other lines against the Voronezh include 9...f5 leading to sharp play. Other solid moves such as 9...e6, ...Bd7, ...Bf5, and ...a5 are possible as well. According to John Cox, the 9...e5 line is adequate, but Black needs to know the line well.