In 2001, Brodie-Sangster's first acting role was in a BBC television film, "Station Jim". He subsequently appeared in a few more television films, including the lead roles in "Bobbie's Girl", "The Miracle of the Cards" (based on the story of Craig Shergold) and "Stig of the Dump". He won the "Golden Nymph" award at the 43rd Annual Monte Carlo Television Festival for his role in the miniseries "Entrusted". Brodie-Sangster's first major theatrical film was "Love Actually" (2003), in which he played Sam. He was nominated for a Golden Satellite Award and a Young Artist Award for his role in the film.