Louisa was sickly, and suffered from migraine headaches and frequent fainting spells. She had several miscarriages over the course of her marriage. Having grown up in London and France, she found Massachusetts dull and provincial, and referred to the Adams family home as being "like something out of Noah's Ark". Nevertheless, she developed a warm affection for her father-in-law, and despite occasional differences, a deep respect for her mother-in-law Abigail Adams, whom she later described as "the guiding planet round which we all revolved".