In "Mandragola", Ligurio is the mastermind behind the manipulation, the root of the play's dramatic deception. Many scholars have interpreted Ligurio, the ultimate symbol of virtú in "Mandragola", as a ‘self-portrait’ of Machiavelli. Ligurio assembles the spectrum of schemes in the play, from the Mandrake potion, to Frate Timoteo's assistance, to Callimaco's disguise and capture by Nicia. Though every character in the play participates in some form of a manipulative act, Ligurio stands out because of his impressive adaptability to tribulations.