The whole church was left burned out on the night of 24 September 1940 during the Blitz, apart from the tower, which was left derelict. St Thomas's Regent Street (now demolished) and the adjoining St Anne's House in the "Upper Room" (now known as the "Allen Room") were used for worship from then on. Though Jacques Groag in 1945 proposed keeping the ruins as a war memorial, it was by 1949 assumed that the church would not be rebuilt, so in 1953 the remains of the east wall (the only significant parts left standing) were demolished, the site deconsecrated and prepared for sale and the parish amalgamated with those of the churches of St Thomas's Regent Street and St Peter's Great Windmill Street (creating the Parish of St Anne with St Thomas and St Peter, centred on St Thomas's).