DeVitto dedicates much of her time to philanthropy and notably supports various charities. She has been A Hospice Ambassador for the National Hospice and Palliative Care Organization since 2011. In 2013, she received National Hospice Foundation's Buchwald Spirit Award for Public Awareness. While filming for television series "Chicago Med" in Chicago, she works with Rainbow Hospice. DeVitto has been particularly involved in hospice care, saying "The notion that 'No one dies alone' was so beautiful to me and one I knew I needed to be a part of. There is no difference to me helping those coming into this world and those going out. It is equally important and should be treated as such. End of life care is something I will always be involved with."