Pío Valenzuela y Alejandrino (July 11, 1869 – April 6, 1956) was a Filipino physician and revolutionary leader. At the age of 23, he joined the society of Katipunan, a movement which sought the independence of the Philippines from Spanish colonial rule and started the Philippine Revolution. Together with Andrés Bonifacio and Emilio Jacinto, they formed the secret chamber of the society called "Camara Reina". He took charge of the publication of "Ang Kalayaan", Katipunan's first and only official publication. He was the one who tried to convince the exiled José Rizal to join the revolutionary movement.