The large grains in interstellar space are probably complex, with refractory cores that condensed within stellar outflows topped by layers acquired during incursions into cold dense interstellar clouds. That cyclic process of growth and destruction outside of the clouds has been modeled to demonstrate that the cores live much longer than the average lifetime of dust mass. Those cores mostly start with silicate particles condensing in the atmospheres of cool, oxygen-rich red-giants and carbon grains condensing in the atmospheres of cool carbon stars. Red giants have evolved or altered off the main sequence and have entered the giant phase of their evolution and are the major source of refractory dust grain cores in galaxies. Those refractory cores are also called stardust (section above), which is a scientific term for the small fraction of cosmic dust that condensed thermally within stellar gases as they were ejected from the stars. Several percent of refractory grain cores have condensed within expanding interiors of supernovae, a type of cosmic decompression chamber. Meteoriticists who study refractory stardust (extracted from meteorites) often call it presolar grains but that within meteorites is only a small fraction of all presolar dust. Stardust condenses within the stars via considerably different condensation chemistry than that of the bulk of cosmic dust, which accretes cold onto preexisting dust in dark molecular clouds of the galaxy. Those molecular clouds are very cold, typically less than 50K, so that ices of many kinds may accrete onto grains, in cases only to be destroyed or split apart by radiation and sublimation into a gas component. Finally, as the Solar System formed many interstellar dust grains were further modified by coalescence and chemical reactions in the planetary accretion disk. The history of the various types of grains in the early Solar System is complicated and only partially understood.