"Mystery of Time and Space" is considered to be a highly significant escape the room adventure that helped propel the genre to significance as a subset of online games. It has been referenced in other adventure games, such as the similarly alien-themed "Cybee's Adventure", in which a "MOTAS Deluxe box" appears as an item. The credits of the seminal escape the room adventure "Crimson Room" name MOTAS as an inspiration. Channel 4 has commented on the game, describing it as ""a treat"" with ""intricate problems"", although it also criticized the game for the obscurity and difficulty of its puzzles.