Madeline La Framboise (1780–1846), born Marguerite-Magdelaine Marcot, was one of the most successful fur traders in the Northwest Territory of the United States, in the area of present-day western Michigan. Of mixed Odawa and French descent, she was fluent in the Odawa, French, English and Ojibwe languages of the region, and partnered with her husband. After he was murdered in 1806, she successfully managed her fur trade business for more than a decade, even against the competition of John Jacob Astor. After retiring from the trade, she built a fine home on Mackinac Island.