In 2000, Feldman became Director of the Juvenile Diabetes Research Foundation Center for the Study of Complications in Diabetes (until 2010), Director of the ALS Center of Excellence at Michigan Medicine, and a fully endowed professor, the Russell N. DeJong Professor of Neurology. In 2005, she was named the Director of Michigan Medicine’s Neuropathy Center. She was appointed the inaugural Director of the A. Alfred Taubman Medical Research Institute in 2007, after U-M received a $100-million-dollar gift from A. Alfred Taubman. She remained Director for a decade.