DeVitto appeared in Will.I.Am's Vote Obama video "We Are The Ones" (2008) and Stevie Nicks' music video for the song "Moonlight" (2011). In 2010, DeVitto began a recurring role as Melissa Hastings in the ABC Family mystery drama series "Pretty Little Liars" based on Sara Shepard's book series of the same name. In 2017, Samantha Simon of "InStyle" wrote that "for Torrey DeVitto, playing super-sketchy Melissa Hastings on "Pretty Little Liars" wasn’t exactly a challenge. Because, despite the seemingly endless web of lies surrounding the eldest Hastings sister on the show, it all looks like child’s play compared to DeVitto’s other unforgettable role as psychotic Nanny Carrie on "One Tree Hill"." She played Nina in the horror film "The Rite" (2011) alongside Anthony Hopkins, Alice Braga and Colin O'Donoghue. It received favorable reviews from critics and grossed over $97 million at the worldwide box office.