The game follows the five Simpson family members—Homer, Marge, Bart, Lisa and Maggie—who learn they are part of a video game and are given superpowers to resolve several situations. Eventually, they must save their 8-bit predecessors from Will Wright, and the creator of their video game character selves, Matt Groening. The Simpson family travels to four scenarios in parodies of other games to collect key cards used to infiltrate their creator's mansion and ultimately to save their predecessors from destruction to reverse the family's ban on video games.