"Aliger gigas" is a prey species for several carnivorous gastropod mollusks, including the apple murex "Phyllonotus pomum", the horse conch "Triplofusus papillosus", the lamp shell "Turbinella angulata", the moon snails "Natica" spp. and "Polinices" spp., the muricid snail "Murex margaritensis", the trumpet triton "Charonia variegata" and the tulip snail "Fasciolaria tulipa". Crustaceans are also conch predators, such as the blue crab "Callinectes sapidus", the box crab "Calappa gallus", the giant hermit crab "Petrochirus diogenes", the spiny lobster "Panulirus argus" and others. Sea stars, vertebrates, horse conch, octopus eagle ray, nurse shark, fish (such as the permit "Trachinotus falcatus" and the porcupine fish "Diodon hystrix"), loggerhead sea turtles ("Caretta caretta") and humans also eat the queen conch.