The Duke Francis helped to defeat the Huguenots at the Battle of Dreux, but he was assassinated shortly afterwards at the Siege of Orleans, in 1563. His son, Henry of Guise, became the third Duke of Guise (1550–1588). He helped plan the infamous St. Bartholomew's Day Massacre of the Huguenots and formed the Catholic League. The death of the royal heir-presumptive, Francis, Duke of Anjou, in 1584, which made the Protestant King Henry of Navarre heir to the French throne, led to a new civil war, the War of the Three Henries, with King Henry III of France, Henry of Navarre, and Henry of Guise all fighting for control of France. Guise began the war by declaring the unacceptability of Navarre as King of France, and his control of the powerful Catholic League soon forced the French king to follow in his wake. In 1588 Guise, with Spanish support, instigated a revolt against the king, taking control of the city of Paris and becoming the de facto ruler.