"Dr. Byrds & Mr. Hyde" was released on March 5, 1969, in the United States (catalogue item CS 9755) and April 25, 1969, in the United Kingdom (catalogue item 63545 in mono, S 63545 in stereo). Like the Byrds' previous LP, "Sweetheart of the Rodeo", the album was issued exclusively in stereo in America, but appeared in both mono and stereo variations in the UK. Sales of "Dr. Byrds & Mr. Hyde" were poor in the U.S., causing it to stall at number 153 on the "Billboard" Top LPs chart and giving the album the dubious honor of being the lowest charting album of the band's career, edging out the later "Farther Along" by just one place. The album fared better in the United Kingdom, however, where it reached number 15 on the UK Albums Chart. The "Bad Night at the Whiskey" single was released ahead of the album on January 7, 1969, but it failed to reach the "Billboard" Hot 100 or the UK Singles Chart.