During World War II, German forces used the fortress for ammunition storage. On June 5, 1941, the ammunition exploded, blasting through the entirety of Smederevo and reaching settlements as far as 10 kilometers away. Much of the southern wall of the fortress was destroyed, the nearby railway station, packed with people, was blown away, and most of the buildings in the city were turned into debris. Around 2,500 people died in the explosion, and every other inhabitant was injured or wounded (approximately 5,500). Bombing by the Allies in 1944 caused further damage.