Since 2000, teams or individuals from DeLaSalle have qualified for participation in the MSHSL's championship tournaments in speech, one-act play, boys' and girls' basketball, football, boys' soccer, boys' and girls' track-and-field, wrestling, cross country, and baseball. DeLaSalle students have succeeded in other programs not directed by the MSHSL, including competitive cheer (eight state titles), Quiz Bowl (eleven straight years qualifying for the National Championships), and musical theatre (20 group or individual awards earned in the annual Spotlight Program of the Hennepin Theatre Trust in 2017). Of note, nearly 45 percent of the students are in a music program, one of three bands, two choirs or orchestra.