Tweetsie Railroad is open from early April through October, and on select nights in late November through December for the Tweetsie Christmas event. In addition to the Wild West train adventure and the amusement rides, Tweetsie Railroad has a variety of live entertainment shows featuring talented performers selected from the immediate area and from the Southeast. The park hosts numerous special events each season, including Letterland-themed days in May for school groups, visits by Thomas the Tank Engine, and a very popular nighttime "Ghost Train" Halloween event in October. In 2017, Tweetsie Railroad's 60th anniversary season, the park introduced the "Tweetsie Christmas" holiday-themed event.