A number of studies have attempted to assess the medical risks for long-term space station habitation, but the results are inconclusive, as epidemiological data is lacking. It is, however, understood that longer periods in space increase the risk of serious problems. The closest estimates show an illness/injury rate of 1:3 per year, with 1% estimated to require emergency evacuation by means of a CRV. For an eight-person ISS crew, this results in an expected need for a CRV flight once every 4 to 12 years. These estimates have been partially corroborated by experiences on board the Soviet Union's "Mir" space station. In the 1980s, the Soviets had at least three incidents where cosmonauts had to be returned under urgent medical conditions.