He provoked the Uddanam kidney disease crisis by various protests and a hunger strike, which was later controlled by the Government of Andhra Pradesh by constructing dialysis centres and implementing various schemes for the village. In November 2016, Kalyan announced that Jana Sena will contest in the 2019 general elections in Andhra Pradesh. He stated that he was planning to contest from all 175 legislatures of Andhra Pradesh without any alliance. He opposed central government's move to privatise Dredging Corporation of India (DCI) on a golden platter. Pawan lead a protest march to condolence farmers who committed suicides or migrated from the drought-prone regions of Rayalaseema. He opposed the Telugu Desam Party Government's decision on land pooling. Kalyan conducted a march on the historical Dowleswaram Barrage in Rajahmundry demanding political accountability. He exposed the alleged unchecked mining in the reserve forest area at Vanthada village of Prathipadu in East Godavari district.