In the mid 18th century, a man named John Homan built two mills along the Carmans River, which runs directly through the center of the town. These two mills inspired the first name for the town: Millville. The translator/author Mary Louise Booth was born in Millville in 1831. In 1846 a post office was opened in the town, but because there were thirteen other towns named "Millville" in New York state at the time, the town was renamed "Yaphank", from the local Native American word "Yamphanke", meaning "bank of a river".