Whilst Worthington-Evans was Secretary of State for War he famously said "If the Arab population realised that the peaceful control of Mesopotamia (Iraq) ultimately depends on our intention of bombing women and children, I’m very doubtful if we shall gain that acquiescence of the fathers and husbands of Mesopotamia to which the Secretary of State for the Colonies (Winston Churchill) looks forward." He was one of the British delegates to the International Economic Conference at Genoa in 1922. He was a member of several Conservative and Unionist Party committees including the Policy committee which he chaired in 1927. He also served on various Cabinet Committees, including those relating to Northern Ireland, and Unemployment. He became chairman of the latter in August 1923. He was a member of the British delegation that negotiated the Anglo-Irish Treaty.