Desprez's most frequently played work was his 1879 two-act musical play, "Tita in Thibet", which was later played in the British provinces by the Majilton company more than a thousand times. It was written as a vehicle for the music hall star Kate Santley. W. H. Seymour, who would become the stage manager of the D'Oyly Carte Opera Company for 20 years, also played in the piece. The story concerns an unusual marriage custom purportedly to be found "in out of the way parts of the world" such as Tibet. The customs of the country permit every wife to have four husbands. The reviewer from "The Era" did not find the piece "refined" enough for his taste.