I-516 is one of a small handful of interstate highways that is not a freeway for its entire length. The southeasternmost half mile downgrades to an expressway with a 45 mile-per-hour speed limit, an at-grade intersection at Mildred Street, a right turn lane onto the De Renne Avenue frontage road, and a 35 mile-per-hour school zone designation following the frontage road right turn to the interstate's eastern terminus at Montgomery Street. The southbound entrance onto Mildred Street is often closed by concrete barriers, as it's primarily used to directly access Hunter Army Air Field from the interstate.