The eastern end of Boxford is crossed by Interstate 95, with three exits lying within the town. Route 133 crosses through the northern part of town, from North Andover to Georgetown, and Route 97 crosses through the eastern part of town, from Topsfield to Georgetown. The town does not have any means of mass transportation. The Newburyport/Rockport Line of the MBTA Commuter Rail passes through neighboring Rowley and Ipswich to the east, and the Haverhill/Reading Line passes to the north. The nearest small airport is Lawrence Municipal Airport, located in North Andover, and the nearest domestic and international air service is Logan International Airport.