The Compton Herbarium was founded after the Bolus Herbarium moved from Kirstenbosch to the campus of the University of Cape Town. Prof. Robert Harold Compton, the second director of Kirstenbosch, kept a small herbarium in his office since 1937. In 1940, this was moved to where the Bolus Herbarium had once stood. Later, the Iziko South African Museum Herbarium and the Stellenbosch Government Herbarium were transferred here as well. Since 1996, the collections have been based in a new, modern research complex.