Prepon was named one of "Stuff" magazine's "102 Sexiest Women In The World" in 2002 and one of "Maxim" magazine's "Hot 100" in 2005. Prepon had a cameo voice appearance as a United Nations Space Command marine in "Halo 2", which was released in 2004. Her first notable film role came in 2004 with the dark drama "Lightning Bug" with Bret Harrison, Kevin Gage and Ashley Laurence. Branching into other arenas than acting, Prepon also served as executive producer of the film. She also appeared on an episode of "MTV's Cribs" in 2003.