In the off-season, Desjardins was traded to the Quebec Remparts. Undrafted and as a 20-year-old player that meant it was his last year in the QMJHL. In the QMJHL finals against the Moncton Wildcats, they lost the series 4-2, but they went to the Memorial Cup tournament because Moncton was the host team. In the Memorial Cup finals against the Wildcats, Desjardins stopped 46 of 48 shots on the way to a 6-2 win and the 2006 Memorial Cup. He also won the Hap Emms Memorial Trophy as the most valuable goaltender at the tournament.