KSHV officially joined MyNetworkTV upon that network's launch on September 5, 2006; although, unlike other WB- and UPN-affiliated stations that were committed to join MyNetworkTV, The WB's prime time programming was carried by KPXJ between 12:00 a.m. and 2:00 a.m. weeknights and 11:00 p.m. and 2:00 a.m. Sunday/early Mondays until September 17, the day before the network formally ceased operations. KPXJ remained a UPN affiliate until September 15, and officially affiliated with The CW when that network debuted on September 18. The station also carried classic television series from the Retro Television Network from September 2008 to January 2009.