Preston played clavinet on the song "Warlocks" for the Red Hot Chili Peppers album "Stadium Arcadium" (2006). Although very ill by this point, he jumped out of his bed after hearing a tape of the song given to him by the band, recorded his part, and went back to bed. Preston's final recorded contributions were the gospel-tinged organ on the Neil Diamond album "12 Songs" (2005), and his keyboard work on "The Road to Escondido" (2006) by Eric Clapton and J. J. Cale.