Another area of interest to the military is the use of human enhancement drugs. DARPA (Defense Advanced Research Projects Agency), a Pentagon branch of the United States Department of Defense, is responsible for significant amount of military research and development of technology. With the announcement of the BRAIN Initiative in 2013, DARPA began to support this initiative through a number of programs involving under-researched neuroscience topics like neuromodulation, proprioception, and neurotechnology. A current operation of DARPA is named the Preventing Sleep Deprivation Program, which conducts research on the molecular processes and changes in the brain involved with sleep deprivation, with the ultimate purpose to maximize warfighters’ cognitive abilities, even with sleep deprivation. As a result of this research, sleep deprivation prevention drugs such as Modafinil and Ampakine CX717 have increased in significance. However, because these chemical drugs directly affect natural chemical reactions and receptors in the body, the ethics of their use as well as safety are in question.