A fashion model discovered as a teenager by "Vogue" editor Diana Vreeland, Berenson came to prominence in the 1960s ("I once was one of the highest paid models in the world", she told "The New York Times"). She appeared on the cover of the July 1970 issue of "Vogue" as well as the cover of "Time" on December 15, 1975. She appeared in numerous fashion layouts in "Vogue" in the late 1960s and early 1970s. She was known as "The Queen of the Scene" for her frequent appearances at nightclubs and other social venues in her youth, and Yves Saint Laurent dubbed her "the girl of the Seventies".