On 22 January 2016, he accomplished his first EuroLeague victory as a head coach, when Žalgiris shockingly crushed the previous season's runners-up, Olympiacos, by a score of 75–55, at Žalgiris Arena. On 26 October 2016, just before the first game versus his former long-time head coach Željko Obradović, Željko said: "I knew that he will be a good coach and in the future - one of the best in Europe". On 13 June 2017, he was named best coach of the 2016–17 LKL season. After the season, San Antonio Spurs and U.S. national team head coach Gregg Popovich invited him to join his coaching staff during the 2017 NBA Summer League. However, Jasikevičius declined, due to his already early planned summer. Jasikevičius also took third place in the voting for the 2017 Alexander Gomelsky EuroLeague Coach of the Year award.