As an undergraduate, Sachs collected prints and drawings with classmate Edward Waldo Forbes, who would eventually become director of Harvard University's Fogg Museum of Art in 1909. After graduating, Sachs went to work in the family business, becoming a partner in 1904. Sachs had been making donations to the Fogg since 1911, then only a small art collection consisting mostly of out-of-fashion American paintings and primitive Italian works. In 1912, Sachs was appointed to the museum's Visiting Committee. Two years later, Forbes persuaded Sachs to leave his family business to become an assistant curator, despite Sachs having no curatorial background. Sachs spent that summer in Italy seeing as much art as possible before his arrival at Harvard in the autumn of 1915.