From Glenholme, Trunk 2 continues west along the north shore of the Minas Basin through Great Village, Bass River, Economy, and Five Islands forming parts of the Glooscap Trail and Fundy Shore Ecotour. At the town of Parrsboro, Trunk 2 turns north through the Cobequid Hills to Newville Lake before turning northeast to reach the Southampton River, which Trunk 2 follows to the town of Springhill. Trunk 2 turns northwest from Springhill and runs a further 30 km to the town of Amherst which it passes through until it reaches the rural community of Fort Lawrence on the interprovincial boundary with New Brunswick.