As the middle ground between King and Parliament vanished in 1641–1642, Ussher was forced, reluctantly, to choose between his Calvinist allies in parliament and his instinctive loyalty to the monarchy. Eventually, in January 1642 (having asked parliament's permission), he moved to Oxford, a royalist stronghold. Though Charles severely tested Ussher's loyalty by negotiating with the Catholic Irish, the Primate remained committed to the royal cause, though as king's fortunes waned Ussher had to move on to Bristol, Cardiff, and then to St Donat's.