MD 322 begins at a directional intersection with US 50 (Ocean Gateway) south of Easton; there is no direct access from southbound MD 322 to westbound US 50. MD 322 heads north as a four-lane divided highway to MD 565 (Washington Street). Beyond this intersection, the state highway reduces to a two-lane undivided road, curves to the northwest, and crosses Paper Mill Pond. MD 332 parallels the pond through the highway's intersection with MD 333, which heads southwest as Oxford Road and northeast as Peach Blossom Road. After the pond turns west, the state highway intersects Port Street, which heads east toward downtown Easton as MD 334 and west as a county highway into the Easton Point industrial area.