Along with Marco Pannella, another member of the Radical Party, Bonino has fought numerous battles for civil rights and individual liberty, mainly concerned with divorce, the legalisation of abortion, the legalisation of drugs, and for sexual and religious freedoms. She has fought for an end to capital punishment, against female genital mutilation, and the eradication of world hunger. In 1975, Bonino funded the information centre for abortion (CISA), and in 1997 she supported the international movement condemning the discrimination of females in Afghanistan, "'Un Fiore per le Donne di Kabul'" (A Flower for the Women of Kabul). Bonino is also a champion of the recognition of women's rights in the countries of the African Union through the Maputo protocol. She is a founder of the nongovernmental organizations "'Non c'è Pace senza Giustizia'" (No Peace Without Justice), which supports the international protection and promotion of human rights and democracy, and "'Nessuno Tocchi Caino (Hands Off Cain), which is an international league that fights for the abolition of the death penalty.