In the season, Mitre won a career-high five games. He also set career bests with 27 games played, 27 starts, 149.0 innings pitched and 80 strikeouts. Mitre had a streak of not allowing an earned run in 24.2 consecutive innings. This streak lasted five starts, beginning May 20 at Tampa and ending June 15 at Kansas City. He made Marlins history with his 1.12 ERA in May, the second lowest for a starting pitcher during May in Marlins history, a feat only topped by Chris Hammond, who turned in a 0.61 ERA in May . Mitre began to see injury problems beginning in 2007, missing two weeks with a blister on his right middle finger, and time later in the season for a strained right hamstring. He had three stints on the disabled list, foreshadowing his season.