The complex was expanded at various times to include over forty buildings and structures. The main part of the hospital (known as "the Kirkbride Building") closed in 1975, and the buildings fell into disrepair. In 1994, the property was added to the National Register of Historic Places as a historic district. In 1999, the main dome of the administration building collapsed. In 2006, a large part of the historic complex was destroyed by fire. In 2009, the remaining parts were demolished. However, many of the newer buildings on the campus remain.