During the Titans first game, a 13–10 win against the Jacksonville Jaguars, Young threw for 78 yards with 1 interception and ran for 22 yards, including a touchdown. In Week 2, the Titans lost 22–20 to the Indianapolis Colts at home. Vince threw for 164 yards and a touchdown and ran for 53 yards on 5 carries. During Week 3, the Titans played the New Orleans Saints in the first of their 2 appearances on Monday Night Football in the 2007 season. The Titans beat the Saints 31–14 behind Young's 185 total yards (21 rushing, 164 passing) and 2 touchdowns with 1 interception. On Sunday October 7, Vince Young and the Titans took to the field in Nashville as they took on the Atlanta Falcons. Despite a lackluster day, the Titans and Young would come away with the victory 20–13. Young was 20–33 with 153 yards and 3 interceptions.