The core concept of "100 Bullets" is based on the question of people willing to act on the desire of violent revenge if given the means, opportunity, and a reasonable chance to succeed. Many of the first issues involve the mysterious Agent Graves approaching someone who has been a victim of a terrible wrong. Graves gives them the opportunity to take revenge by providing a handgun, 100 bullets, and documentation about the primary target responsible for their woes. He informs the candidate the bullets are completely untraceable by any law enforcement investigation, and as soon as they are found at any crime scene, investigations will immediately cease.