Pittsfield is at the crossroads of U.S. Route 7 and U.S. Route 20 which join together in the city. Massachusetts Route 8 passes through the northeast corner of town, with a portion of it combined with Route 9, the central east-west road through the western part of the state, whose western terminus is in the city at Route 20. Route 41 begins in the southwest corner of town, heading south from Route 20. The nearest interstate highway, Interstate 90 (the Massachusetts Turnpike) is about south in Lee.