The first written evidence of Nusle, as a village, dates back to the 11th century. It is recorded as Neosvětly, Nostuly, Nusle, Neosvitly or Neovstlí in the Middle Ages and the bulk of its territory consisted of vineyards (Vallis Vinarium or Valis vinearum), wine houses, mills by the Botič stream, homesteads (Bučanka, Belka, Terebovka, Reitknechtka, Formanka), a coaching inn, a lodge, and the St. Pankratz church in the part of Nusle named Krušina, residential farm houses in Lower and Upper Nusle, a meat market, and from the 17th century a mansion and brewery. Prior to 1750 there was an estate outside the mansion buildings comprising 35 houses. It was not until 1797, when colonel nobleman James Wimmer bought Nusle that the rural character disappeared.