The economy of Müllheim was characterized by wine, fruit, flax and hemp production as well as forestry and dairy farming and cheese making. The municipality had several handicraft businesses and restaurants, as well as two annual fairs. The train station Müllheim-Wigoltingen opened in 1855. This train station encouraged the construction in 1857 of a canvas factory in Grüneck. In 1979 this became the weaving factory of Grüneta AG, which went bankrupt in 2004. The Utilis Müllheim tool factory was founded in 1870 and employed 40 staff in 2000. Other businesses in the municipality included an embroidery factory in 1900, a wood turning plant that was open between 1909–16 and a machine shop from 1906-09. Since 1954, a local company manufactures steel furniture, another has recycled industrial waste since 1991.