Interstate 5 (I-5) runs through Sacramento, heads north up to Redding, and then heads south near the western edge of the California Central Valley towards Los Angeles. California State Highway 99 runs through Sacramento, heading closer to the eastern edge of the Central Valley, connecting to Marysville and Yuba City in the north, and Fresno and Bakersfield in the south. California State Highway 160 approaches the city after running along the Sacramento River from Contra Costa County in the south, and then becomes a major city street in Downtown Sacramento before turning into the North Sacramento Freeway, going over the American River to Business 80.