Chabert played the title role in "The Brooke Ellison Story", a movie produced and directed by Christopher Reeve, based upon a real-life quadriplegic woman who overcame many obstacles to graduate from Harvard University. She co-starred in "Mean Girls" (2004) and the television film "Hello Sister, Goodbye Life" (2006) on ABC Family. She appeared in a 2006 remake of "Black Christmas". She appeared in an episode of "Ghost Whisperer" opposite former "Party of Five" costar Jennifer Love Hewitt. She performed the voice of Princess Elise from the game "Sonic the Hedgehog" for the PlayStation 3 and Xbox 360. She also voiced Gwen Stacy in the animated series "The Spectacular Spider-Man".