Sami I. Haddad worked at AUB as professor of surgery and urology, chairman of the surgery department, and dean of the medical school. In 1947, he left AUB to found a non-profit hospital called the Orient Hospital where he served as director and chief surgeon, until his death in 1957. With his wife Lamia, they had 6 children: Farid (urologist and surgeon), Fuad (neurosurgeon), Brahim (engineer), Samia (pianist), Labib (mathematician) and Saad (physicist and architect). He bought a house on the same block as the Orient Hospital, in a district of downtown Beirut called Haouz Saatiyeh, where he spent the last ten years of his life. Note that his second son Dr. Fuad Sami Haddad was "...the founder of modern neurosurgery in Lebanon."