The Enterprise Academy had in "excess of one hundred students" in its early years of operation (for comparison, about the same number then enrolled at Ohio University at the same time). With the increase in students, a second building for a girl's dormitory was built in 1870. By the late 1870s, many blacks had left the area for work in larger cities and local public integrated schools were available. As a result, the Enterprise Academy suffered declining enrollment; it closed in 1886.