Kuby dropped out of college in 1974 and moved to St. Croix, in the U.S. Virgin Islands, where he worked on a tugboat and developed an interest in West Indian ethnobotany and medicinal plants. He moved briefly to Maine, then to Kansas in 1975, where he completed his degrees in cultural anthropology and history at the University of Kansas. Kuby was a free-speech and anti-apartheid activist while at KU, where he graduated with highest distinction, had a 4.0 average, and conducted and published original fieldwork, including the 1979 "Folk medicine on St. Croix: an ethnobotanical study", after returning to St. Croix several times. Kuby alleged Kansas University police intentionally broke his arm when they responded to an anti-apartheid protest during a commencement ceremony. Protesters were urging the KU Endowment Association to divest itself of investments in companies doing business in South Africa.