In the UK and Ireland the 15/500 and 30/500 tablets are available only with a prescription, although the 8/500 strengths are available over-the-counter. In Australia the 30/500 tablets are available only with a prescription, and the 10/500 and 15/500 tablets were Schedule 3 (Pharmacist Only Medicine) until February 1, 2018 after which they were rescheduled to S4 (prescription only) along with all other codeine products. Manufacturer directions state not to exceed the recommended dosage of two tablets every four hours with a maximum of eight (8 × 500 mg) over a 24-hour period and no more than two (2 × 500 mg) at any one time. Other drugs containing paracetamol must be avoided unless otherwise directed by a prescriber or pharmacist; excessive amounts of paracetamol can lead to serious liver damage. See paracetamol toxicity.