A commission under the Great Seal sat at Wigan in 1650 and considered that a chapel should be built for the townships of Lowton, Golborne and Kenyon. Some eighty years later, under the "Lowton Chapel Agreement" of 1 December 1731, twenty-seven charterers and freeholders within the township of Lowton agreed to enclose eleven acres of waste and common land on Lowton Common and on Lowton Heath, near the Locking Stoops, "for the erecting of a Chapel of Ease, and of a convenient schoolhouse", with the consent of Peter Legh, Lord of the Manor of Lowton. A date of 1732 on the church door suggests that the building was completed within a year. The Chapel was consecrated on 18 October 1733, St Luke's Day, by the Bishop of Chester. The chapel and chapel yard were built on land given by Hugh Stirrup, a yeoman of Lowton.