Lisson Green is described as a hamlet in the Domesday book in 1086, the edges of the settlement defined by the two current Edgware Road stations facing onto Edgware Road or Watling Street as it was previously known, one of the main Roman thoroughfares in and out of London. Occasionally referred to as Lissom Grove, originally Lisson Grove was part of the medieval manor of Lilestone which stretched as far as Hampstead. Lisson Green as a manor broke away with its own manor house.