In 1768, the Spanish government expelled the Jesuits from Baja California. The new Spanish administration and newly arrived Franciscan missionaries forced the 746 survivors of the northern bands of the Guaycura to move south to Todos Santos. A year later more than 300 had died in a measles epidemic. Many of the Guaycura were still semi-nomadic and the efforts of the Franciscans to make of them toilers of the soil on mission lands was a failure as many ran away. By 1808 only 82 Guaycura were still resident at Todos Santos. Baja California by this time was being settled by Spanish and mestizo immigrants and the remaining Guaycura were being absorbed into the general population and had lost the remnants of their culture.