New York State Route 250 (NY 250) is a north–south state highway in the eastern portion of Monroe County, New York, in the United States. It extends for just over from an intersection with NY 96 in the town of Perinton to a junction with Lake Road (former NY 18) near the Lake Ontario shoreline in the town of Webster. NY 250 passes through the villages of Fairport and Webster, where it meets NY 31F and NY 104, respectively. The highway is the easternmost north–south state route in Monroe County.