Underway for her seventh patrol on 24 November, "Sailfish" proceeded to the area south of New Britain. Following an unsuccessful attack on a destroyer on 2 December, the submarine made no other contacts until 25 December, when she believed she had scored a hit on a Japanese submarine. Postwar analysis of Japanese records could not confirm a sinking in the area. During the remainder of the patrol, she made unsuccessful attacks on a cargo ship and a destroyer before ending the patrol at Pearl Harbor on 15 January 1943.