The men's basketball team reached its first NCAA tournament in 2009 after winning the Southland Conference regular season and tournament. They lost 59–44 to Syracuse University. In their second appearance in 2014, they upset Virginia Commonwealth in overtime, 77–75. In their third appearance in 2016, they upset 3rd seeded West Virginia 70–56. In the second round against 6th seeded Notre Dame they lost 77–76 on a buzzer beater by Notre Dame's Rex Pflueger. On November 26, 2019, in arguably the biggest upset in NCAA Division I basketball in 15 years, SFA upset #1-ranked Duke in overtime by a score of 85–83. This was the first home game against a nonconference opponent that Duke had lost in the Blue Devils' past 150 home games.