Indeed, much of his wealth stems from the fact that he was one of the first English merchants to embark on trade with China, and much of his subsequent trade was with the East Indies. As a devout Christian, he was keen to establish a charity hospital, modelled on the Liverpool Blue Coat School. Having no children, on his death in 1852 he left a considerable sum of money in trust to establish the Ripley Hospital to cater for fatherless children, especially those whose fathers had been lost at sea.