MD 322 temporarily expands to a four-lane undivided highway at its intersection with MD 33, which heads east as Bay Street toward downtown Easton and west as St. Michaels Road. The MD 322–MD 33 intersection lies on a crossing of Tanyard Creek just east of its confluence with an unnamed creek to form the North Fork of the Tred Avon River. MD 322 continues northeast past several shopping centers and industrial parks between MD 33 and Glebe Road. Near its northern terminus, the state highway meets the northern end of Washington Street and Airpark Drive, which immediately has an intersection with MD 662 (Centreville Road) before entering an industrial park adjacent to Easton Airport. MD 322 reaches its northern terminus at a directional intersection with US 50.