In the 2008 World Series, which featured the Philadelphia Phillies and Tampa Bay Rays, Culbreth worked behind home plate for Game 3. The Phillies claimed a 5–4 victory due to a walk–off single by Carlos Ruiz. Philadelphia won the Series in five games. In Game 3 of the 2012 World Series, Culbreth umpired behind the plate for the matchup between the Detroit Tigers and the San Francisco Giants. The Giants shut out the Tigers, 2–0. San Francisco won the World Series in the next game.