Returning a kick in the second half of Columbia's game against Yale, Weekes sprinted 50 yards to score a touchdown. During the run, he successfully thwarted the tackling attempts of several Yale players, including the team captain. Weekes's scoring play for Columbia marked the only points in a 5-0 shutout of Yale. Columbia's surprise upset victory represented the first time in 28 seasons that a team other than Harvard, Princeton, or the University of Pennsylvania shut out Yale. The 1899 victory also marked Columbia's first defeat of Yale in 24 years.