The last of the direct Capetians were the daughters of Philip IV's three sons, and Philip IV's daughter, Isabella. The wife of Edward II of England (1284–1327), Isabella (c.1295–1358) overthrew her husband in favour of her son (Edward III, 1312–1377) ruling as regent with her cohort and lover (Roger Mortimer, 1st Earl of March, 1287–1330). On the death of her brother, Charles IV, in 1328 she claimed to be her father's heiress, and demanded the throne pass to her son (who as a male, an heir to Philip IV, and of adult age, was considered to have a good claim to the throne); however, her claim was refused, eventually providing a cause for the Hundred Years' War.