As the former Chief Operating Officer of The Global Fund, a private Swiss foundation created by the world’s top developed countries, Mailer, along with the Geneva based team, raised and distributed funds to support the fight against AIDS, tuberculosis and malaria in developing countries. She created and managed the fund’s administrative operations in collaboration with international partners, including the World Bank and World Health Organization. During her tenure, some $3.4 billion was raised from international donors, $33 million of which was disbursed in grant funds to 92 countries.