The Butterworth railway station is one of the major stations along the Malayan Railway's west coast route. As such, regular Malayan Railway services are available to other cities along western Peninsular Malaysia, including Ipoh, Kuala Lumpur, Malacca and Johor Bahru, as well as on to Woodlands in northern Singapore. Aside from these, the Butterworth railway station is also the terminus of the State Railway of Thailand's Southern Line (via Padang Besar) and the International Express from Bangkok. Notably, the train station is one of the main stops of the Eastern and Oriental Express service between Bangkok and Singapore as well.