Akanthos (; ) was an ancient Greek city on the Athos peninsula, on the narrow neck of land between the sacred mountain and the mainland, to the northwest of the Xerxes Canal. It was founded in the 7th century BCE as a colony of Andros, itself a colony of Chalcis in Euboea. Chalcidice was multi-cultural. The archaeology of the region suggests that some Hellenes were already there. The site is on the north-east side of Akti, on the most eastern peninsula of Chalcidice.