According to fellow anthropologist Charles E. Dibble, "In the brief span of a decade, Barlow gave Middle American research an impetus and perspective of enduring consequence. His contributions in Mexican archaeology, classical and modern Nahuatl, Mexican colonial history, and what he preferred to call "Bilderhandschriften" are of lasting importance." Dibble compared Barlow's zeal for searching for and deciphering little known or dimly recalled codices and colonial manuscripts to that of Zelia Nuttall. Barlow has been referred to as "the T. E. Lawrence of Mexico."