Palmer defeated Pennsylvania's incumbent Democratic National Committeeman, Colonel , by a resounding margin of 110 to 71 at the State Party's annual convention in 1912. Guffey had been a dominant force in state Democratic politics for a half-century; his defeat at the hands of Palmer was seen as a major victory for the Progressive-wing of the State Party, though Guffey's nephew, Joe, would go on to succeed Palmer as the state's National Committeeman in 1920. Palmer served as a delegate to the Democratic National Convention in both 1912 and 1916. At the 1912 Convention, he played a key role in holding the Pennsylvania delegation together in voting for Woodrow Wilson. Following the election of 1912, Palmer hoped to join Wilson's Cabinet as Attorney General. When he was offered Secretary of War instead, he declined citing his Quaker beliefs and heritage. He wrote to the President: