After a going winless in tournaments throughout the months of March and April, which includes the BNP Paribas Open and Miami Open, Pavlyuchenkova advanced to the round of 16 at the Mutua Madrid Open for the third year in a row. There, she succumbed to eventual runner-up Dominika Cibulková in three sets. At the Internazionali BNL d'Italia, she lost to 13th seed Ana Ivanovic in the first round. At the French Open, Pavlyuchenkova won back-to-back matches at a Grand Slam tournament for the first time since the 2014 Australian Open, defeating the likes of Sara Sorribes Tormo and Çağla Büyükakçay to book her spot in the third round where she was beaten by compatriot Svetlana Kuznetsova.