"Mesa" was one of six 1950s films to make use of wire-controlled giant spiders. The others were "Cat-Women of the Moon" (1953), "Tarantula" (1955), "World Without End" (1956), "Queen of Outer Space" (1958), and "Missile to the Moon" (1958). "Mesa" and "Cat-Women" made use of similar giant spider props. However the spider used in "Mesa" was limited in movement, a single jump being its greatest action feat. The one in "Cat-Women" was created by Wah Chang and was more advanced. Both "Mesa" and "Missile to the Moon" were partially filmed in the Red Rock Canyon State Park.