There are many researchers working on identifying the brain areas involved in the exertion of self-control; many different areas are known to be involved. In relation to self-control mechanisms, the reward centers in the brain compare external stimuli versus internal need states and a person's learning history. At the biological level, a loss of control is thought to be caused by a malfunctioning of a decision mechanism. A mechanistic explanation of self-control is still in its infancy. However, there is strong demand for knowledge about these mechanism because knowledge of these mechanisms would have tremendous clinical application.