Goodman played in 15 games with eight starts for the Lions in 2005. He had 47 tackles and a career-high three interceptions, a figure which ranked second on the club, and also came up with a fumble recovery, 12 passes defensed and a five special teams tackles. He had a season-high six tackles on four occasions, all within the first two months of the regular season. His first interception of the year came in a 13-10 win over the Cleveland Browns on October 23, when he picked off a Trent Dilfer pass in the fourth quarter to help preserve the victory. Against the Cincinnati Bengals on December 18, he intercepted a Carson Palmer pass and returned it a career-long 21 yards. He intercepted a Ben Roethlisberger throw in the season finale against the Pittsburgh Steelers on January 1, 2006.