In 2018, Manchin secured a provision in the Opioid Crisis Response Act that ensured additional opioid funding for West Virginia after the bill had previously granted funding based on states’ overall opioid overdose death counts as opposed to the overdose death rate. Manchin stated that the bill before his intervention was "basically using a blanket before when giving money" and added that the bill was incentivizing "companies to do the research to produce a product that gives the same relief as the opioid does, but is not (addictive)." The bill passed in the Senate in September.