The American Psychiatric Association, in its "Diagnostic and Statistical Manual of Mental Disorders", diagnoses persistent anti-social behaviour as antisocial personality disorder. Genetic factors include abnormalities in the prefrontal cortex of the brain while neurobiological risk include maternal drug use during pregnancy, birth complications, low birth weight, prenatal brain damage, traumatic head injury, and chronic illness. The World Health Organization includes it in the International Classification of Diseases as dissocial personality disorder. A pattern of persistent anti-social behaviours can also be present in children and adolescents diagnosed with conduct problems, including conduct disorder or oppositional defiant disorder under the DSM-5. It has been suggested that individuals with intellectual disabilities have higher tendencies to display anti-social behaviours, but this may be related to social deprivation and mental health problems. More research is required on this topic.