In 2010, Aptowicz was named the 2010–2011 University of Pennsylvania ArtsEdge Writer-in-Residence and she noted that she will be using the residency to work on "a non-fiction book about the life and times of Thomas Dent Mutter." The museum has granted Aptowicz full access to their museum, library and archives for the duration of the residency so that she may conduct her research for the book, and the Mütter Museum's Francis C. Wood Institute for the History of Medicine has additionally awarded Aptowicz with a Wood Institute Travel Grant to help further fund and support her work on this project. In April 2013, it was announced that Aptowicz's biography of Mütter will be published in Fall 2014 by the Gotham Books division of Penguin. On September 4, 2014, "Dr. Mütter's Marvels: A True Tale of Intrigue and Innovation at the Dawn of Modern Medicine" was released to critical acclaim, including starred reviews in Publishers Weekly, Library Journal, School Library Journal and Kirkus Reviews, as well as lengthy positive reviews in the Wall Street Journal, The Onion's AV Club and NPR. The book would debut at #7 on The New York Times Bestseller List for Books about Health.