Captain Wynne viewed the line from Lincoln to Gainsborough on 29 March 1849, but refused permission to open until signals were provided at the swing bridge at Brayford Mere (Lincoln); the line opened on 9 April 1849 when they had been provided. The route made a junction with the Manchester, Sheffield and Lincolnshire Railway at Gainsborough; GNR trains reversed at the junction and used the MS&LR station at Gainsborough. A junction was made with the MS&LR line at Durham Ox Junction, Lincoln, some time after 3 April 1848, and sanctioned by Parliament retrospectively.