Alberta Provincial Highway No. 43, commonly referred to as Highway 43, is a major highway in northern and central Alberta, Canada that connects Edmonton to the British Columbia border via the Peace Country, forming the northernmost portion of the CANAMEX Corridor in Alberta. It stretches approximately from Highway 16 (Yellowhead Highway) near Manly Corner west of Edmonton to the British Columbia border west of Demmitt. It is designated as a core route in Canada's National Highway System, comprising a portion of a key international corridor that stretches from Alaska into Mexico.