With her training cycle complete, "Crommelin" departed Pearl Harbor on 24 August 1999 for a three-month deployment to the Eastern Pacific in support of counter narcotics operations. During this deployment, "Crommelin" steamed 77 of 92 days, flew more than 350 mishap-free SH-60B flight hours, and was a key player in four major cocaine seizures. Upon her return to Pearl Harbor on 24 November 1999, "Crommelin" immediately began the work up cycle for her next deployment with the battle group in August 2000.