A popular belief is that the song title refers to an idea first conceived by Carl Jung and later expounded upon by Drunvalo Melchizedek concerning the possibility of reaching a state of evolution at which the body would have two more than the normal 46 total chromosomes and leave a currently disharmonious state. The premise is humans would deviate from the current state of human DNA which contains 44 autosomes and two sex chromosomes. The next step of evolution would likely result in human DNA being reorganized into 46 autosomes and two sex chromosomes, according to Melchizedek.