1903: Brummie Francis William Aston wins a scholarship to the University of Birmingham and in his studies of electronic discharge tubes he discovers the phenomenon now known as the Aston Dark Space. He later moves to the Cavendish Laboratory in Cambridge, where he uses a method of electromagnetic focusing to invent the mass spectrograph, which rapidly allows him to identify no fewer than 212 of the 287 naturally occurring isotopes. His work on isotopes also leads to his formulation of the Whole Number Rule, which is later used extensively in the development of nuclear energy. In 1922 he wins the Nobel Prize in Chemistry for the invention of the mass spectrometer.