If a human-capability machine construct, such as via mind uploading, is possible, and if it is possible to transfer such constructs over vast distances and rebuild them on a remote machine, then it might not make strong economic sense to travel the galaxy by spaceflight. After the first civilization has physically explored or colonized the galaxy, as well as sent such machines for easy exploration, then any subsequent civilizations, after having contacted the first, may find it cheaper, faster, and easier to explore the galaxy through intelligent mind transfers to the machines built by the first civilization, which is cheaper than spaceflight by a factor of 108-1017. However, since a star system needs only one such remote machine, and the communication is most likely highly directed, transmitted at high-frequencies, and at a minimal power to be economical, such signals would be hard to detect from Earth.