In the video game world, Baker reprised his roles in Cartoon Network and Nickelodeon's multitude of show-related game releases. He also voiced Gravemind in "Halo 2" and "Halo 3," and the title character Joe in the "Viewtiful Joe" series released from 2003 to 2005. He provided the creature sounds for the "Spore" video game which allows players to create and evolve their own creatures. At San Diego Comic-Con 2008's opening night, he was a featured performer at the "Video Games Live" concert, where he voiced characters from "Gears of War" and other series. He provided voices for two Blizzard Entertainment characters – Murky, a baby murloc in "Heroes of the Storm," and Hammond, a genetically engineered hamster in "Overwatch." He is also the voice of Atlas and P-body in "Portal 2", released in 2011. In 2020, he voiced the hero Leef in Rocket Arena.