Frost worked for Al Jazeera English, presenting a live weekly hour-long current affairs programme, "Frost Over The World", which started when the network launched in November 2006. The programme regularly made headlines with interviewees such as Tony Blair, President Omar al-Bashir of Sudan, Prime Minister Benazir Bhutto of Pakistan and President Daniel Ortega of Nicaragua. The programme was produced by the former "Question Time" editor and "Independent on Sunday" journalist Charlie Courtauld. Frost was one of the first to interview the man who authored the Fatwa on Terrorism, Muhammad Tahir-ul-Qadri.