Flanders was an early and strong critic of fellow Republican Senator Joseph McCarthy's "misdirection of our efforts at fighting communism" and his role in "the loss of respect for us in the world at large". He felt that rather than looking inward for communists within U.S. borders, the nation should look outward at the "alarming world-wide advance of Communist power" that would leave the United States and Canada as "the last remnants of the free world". On March 9, 1954 he addressed Senator McCarthy on the Senate floor, expressing these concerns. (McCarthy had been advised of the speech, but was absent at the time.) Apart from a brief note of encouragement after this speech, Flanders was grateful that President Eisenhower stayed out of the McCarthy controversy. Members of President Eisenhower's cabinet passed along the message that Flanders should "lay off."