Razzano started her US Open Series campaign in Los Angeles, where she was seeded 11th. She lost in the first round to Anna Chakvetadze. She was seeded 16th at Cincinnati, but also lost in the first round to Anna-Lena Grönefeld. Razzano played her last tournament before the US Open in New Haven. Unseeded in singles, she defeated world No. 20 Patty Schnyder in three sets, in the first round. Fifth seed Agnieszka Radwańska had to retire due to injury in the second round with the score at one set all. Razzano was defeated by Caroline Wozniacki in the quarterfinals. Razzano was seeded 16th at the US Open, but suffered a surprise defeat in the first round to eventual semifinalist Yanina Wickmayer.