From 2011 to 2018, Espenson worked as a consulting producer and co-executive producer on ABC's series "Once Upon a Time", and also wrote and directed some of the show's supplementary DVD content and helped develop the show's spin-off series. She co-wrote and produced an independent original web series with co-creator Brad Bell, entitled "Husbands". She and Bell were nominated for a Writers' Guild Award for their work on the series. Espenson also contributed writing to seasons 1 and 3 of the Marvel series "Jessica Jones".