Ronald Chernow was born on March 3, 1949, in Brooklyn, New York. His father Israel was the owner of a discount store and creator of a stock brokerage firm; his mother Ruth was a bookkeeper. He is brother to Bart Chernow and uncle to Shandee Chernow. Chernow was voted "Most Likely to Succeed", and was Class President and Valedictorian when he graduated in 1966 from Forest Hills High School in Queens, New York. Chernow graduated "summa cum laude" from Yale University in 1970 and Pembroke College at Cambridge University with degrees in English literature. He began but did not finish a PhD program. He says that in politics he is a "disgruntled Democrat" and gives his religion as "Jewish, though more in the breach than the observance."