Jaffe co-starred in the ABC television series, "Ben Casey" as Dr. David Zorba from 1961 to 1965 alongside Vince Edwards. He also made many guest-starring roles on other series, including "Batman" as Mr. Zoltan Zorba, and the Western "Alias Smith and Jones". In 1975, he co-starred as a retired doctor who is murdered by Janet Leigh in the "Columbo" episode "Forgotten Lady". He also appeared with an all-star cast in the TV pilot film of Rod Serling's "Night Gallery" and as Emperor Norton in one episode of "Bonanza".