Sainte-Marie founded the Cradleboard Teaching Project in October 1996 using funds from her Nihewan Foundation and with a two-year grant from the W.K. Kellogg Foundation of Battle Creek, Michigan. With projects across Mohawk, Cree, Ojibwe, Menominee, Coeur D'Alene, Navajo, Quinault, Hawaiian, and Apache communities in eleven states, partnered with a non-native class of the same grade level for Elementary, Middle, and High School grades in the disciplines of Geography, History, Social Studies, Music and Science and produced a multimedia curriculum CD, "Science: Through Native American Eyes".