From 1916 to 1921, Sofronitsky studied in the Petrograd Conservatory under Leonid Nikolayev, where Dmitri Shostakovich, Maria Yudina, and Elena Scriabina, the eldest daughter of the deceased Alexander Scriabin, were among his classmates. He met Scriabina in 1917 and married her in 1920. While he had already divulged a sympathy for the piano music of the recently deceased mystic composer—as attested by Yudina—he now had a greater intellectual and emotional connection to Scriabin's works through his wife and through the Scriabin in-laws. Sofronitsky was also acclaimed as an outstanding pianist by the composer Alexander Glazunov and the musicologist and critic Alexander Ossovsky.