Croton's oikistes (founder) was Myscellus who came from the city of Rhypes in Achaea in the northern Peloponnese. He established the city in c. 710 BC and it soon became one of the most flourishing cities of Magna Graecia with a population between 50,000 and 80,000 around 500 BC. Its inhabitants were famous for their physical strength and for the simple sobriety of their lives. From 588 BC onwards, Croton produced many generations of victors in the Olympics and the other Panhellenic Games, the most famous of whom was Milo of Croton. According to Herodotus (3.131), the physicians of Croton were considered the foremost among the Greeks, and among them Democedes, son of Calliphon, was the most prominent in the 6th century BC. Accordingly, he traveled around Greece and ended up working in the court of Polycrates, tyrant of Samos. After the tyrant was murdered, Democedes was captured by the Persians and brought to King Darius, curing him of a dislocated ankle. Democedes' fame was, according to Herodotus, the basis for the prestige of Croton's physicians. Pythagoras founded his school, the Pythagoreans, at Croton c. 530 BC. Among his pupils were the early medical theorist Alcmaeon of Croton and the philosopher, mathematician, and astronomer Philolaus. The Pythagoreans acquired considerable influence with the supreme council of one thousand by which the city was ruled. Sybaris was the rival of Croton until 510 BC, when Croton sent an army of one hundred thousand men, commanded by the wrestler Milo, against Sybaris and destroyed it. Shortly afterwards, however, an insurrection took place, led by a prominent citizen, Cylon, by which the Pythagoreans were driven out and a democracy established.