Loyola High School has a strong history of athletics success, including national championships in football and volleyball. Loyola has won at least one California Interscholastic Federation (CIF) title for ten years running, and in 2017 won the CIF Commissioner's Cup for the ninth year in a row. In the 2002-2003 academic year, Loyola set the California state record for most section championships (5) won in a single school year: cross-country, basketball, volleyball, track, and golf. The Cubs matched their still-standing state record in the 2015-2016 school year, winning section titles in Golf, Lacrosse, Swimming, Volleyball, and Soccer.