Born at the Point McLeay Mission on the banks of Lake Alexandrina in the Coorong region of South Australia, Unaipon was the fourth of nine children of James and Nymbulda Ngunaitponi, of the Portaulun branch of the Ngarrindjeri people. Unaipon began his education at the age of seven at the Point McLeay Mission School and soon became known for his intelligence, with the former secretary of the Aborigines' Friends' Association stating in 1887: "I only wish the majority of white boys were as bright, intelligent, well-instructed and well-mannered, as the little fellow I am now taking charge of."