The Moscow Art Theatre traveled widely throughout Europe, and when it arrived in New York City in 1922, Ouspenskaya decided to stay there. She performed regularly on Broadway over the next decade. She taught acting at the American Laboratory Theatre and in 1929, together with Richard Boleslawski, her colleague from the Moscow Art Theatre, she founded the School of Dramatic Art in New York City. One of Ouspenskaya's students at the school during this period was Anne Baxter, then an unknown teenager.