In 2010, Andrews released the Ben Ellman produced "Backatown" (Verve Forecast), which hit "Billboard" magazine's Contemporary Jazz Chart at No. 1 and stayed there for nine consecutive weeks. Trombone Shorty & Orleans Avenue toured across Australia, North America, Europe, Japan and Brazil, as well as supported shows for Jeff Beck in the U.K. and Dave Matthews Band in the U.S. They performed on television shows including "Conan", "Late Show with David Letterman", "The Tonight Show with Jay Leno", "Jimmy Kimmel Live!", "Bonnaroo", and "Austin City Limits". He also recorded on CDs from Galactic, Eric Clapton, and Lenny Kravitz and on the Academy Award nominated song "Down In New Orleans" with Dr. John. In December 2010, Andrews curated a two-night Red Hot+New Orleans performance at the Brooklyn Academy of Music to raise money for the New Orleans NO/AIDS Task Force.