George had worked for Chemical Bank for two years when he decided in 1976 to start his own company, Multinational Computer Models, Inc (MCM), which would offer computerized systems to large multinational corporations to enable them to deal with their international financial risks. MCM subsequently formed a joint venture with the global investment bank Credit Suisse First Boston where George served as the Chief Consultant and Managing Director of its new operations. In 1998, George sold MCM to SunGard Data Systems, a Fortune 500 company, where he served as a Vice-Chairman for two years. He was on the boards of Vellore Christian Medical College & Hospital, International Center for Journalists, and Human Rights Watch.