The Church of "Santa Maria Assunta" is Gissi's oldest church, which was remodeled in 1955. Inside, it houses silver crosses from the Neapolitan School dating to the 17th and 18th centuries, a 17th-century wooden statue of Saint Pamphilus, and a wooden cross from the late 12th. Its ceiling contains a reproduction of the "Annunciation" attributed to Guido Reni, and its 16th century wooden organ is carved and gilded with gold. The church also has two chapels dedicated to the Immaculate Conception and Sacred Heart.