Boutsikaris had a leading part in episode 20 of the second season of the hit CBS show "Person of Interest" which aired in the USA on Thursday, April 26, 2013. He was part of NBC's "State of Affairs", the TV series that marks the return to series television of Katherine Heigl. In 2012, he also made an appearance as Jack Quayle in the season 2 episode "Collateral Damage" of the CBS show "Blue Bloods". In 2015, 2016, 2018, and 2020 he played the role of lawyer Rich Schweikart in the first, second, fourth and fifth seasons of the American series "Better Call Saul". In 2017, Boutsikaris was cast in the recurring role of Henry Roarke on the ABC thriller series "Quantico".