In 1993, paclitaxel was discovered as a natural product in a newly described endophytic fungus living in the yew tree. It has since been reported in a number of other endophytic fungi, including "Nodulisporium sylviforme", "Alternaria taxi", "Cladosporium cladosporioides" MD2, "Metarhizium anisopliae", "Aspergillus candidus" MD3, "Mucor rouxianus", "Chaetomella raphigera", "Phyllosticta tabernaemontanae", "Phomopsis", "Pestalotiopsis pauciseta", "Phyllosticta citricarpa", "Podocarpus" sp., "Fusarium solani", "Pestalotiopsis terminaliae", "Pestalotiopsis breviseta", "Botryodiplodia theobromae", "Gliocladium" sp., "Alternaria alternata" var. "monosporus", "Cladosporium cladosporioides", "Nigrospora" sp., "Pestalotiopsis versicolor", and "Taxomyces andreanae". However, there has been contradictory evidence for its production by endophytes, with other studies finding independent production is unlikely.