Pennsylvania Route 425 (PA 425) is an state highway located in York county in Pennsylvania. The southern terminus is at PA 851 in Fawn Grove. The northern terminus is at PA 124/PA 624 in Craley. PA 425 is a two-lane undivided road that runs through rural areas in southeastern York County. The route heads north from Fawn Grove and passes through Woodbine before it forms a concurrency with PA 74 in Airville. From here, PA 425 heads northeast to York Furnace, where it briefly follows the west bank of the Susquehanna River before heading northwest away from the river. The route continues west to New Bridgeville, where it turns north and curves west to continue to its terminus in Craley.