Pedrosa was the leading member of Martinez's staff on immigration issues, and spearheaded his efforts to obtain passage of comprehensive immigration reform in the United States Senate in 2006 and 2007. To that end, she spoke at various forums on the issue, including the National Council of La Raza and the Greater Miami Chamber of Commerce. She was also a prominent member of the Cuban-American lobby and was an active member of Cuba Democracy Advocates. She was one of the staff members responsible for working on Cuba policy issues in both the US Senate and the US House of Representatives.