Mentallo is a mutant with weak psychic powers which he has had augmented through scientific means throughout his criminal career, often times being provided by the Fixer. Mentallo boasts telepathy able to read the thoughts of any human mind within an approximate five mile (8 km) radius. He has the ability to project "mental bolts" at opponents, create psionic screens to protect himself from psychological assault, control the bodies and minds of other sentients, communicate telepathically, cast mental illusions and psychically possess the bodies of others. Mentallo has difficulty focusing his powers on moving targets. He is unusually vulnerable to psionic attack unless he erects a mental screen.