Wilson made his major league debut with the Giants on September 29, 1923, at the age of 23, and became the starting left fielder the following season. By mid-July he was ranked second in the National League (NL) in hitting. He ended the season with a .295 average, 10 home runs, and 57 runs batted in (RBIs) as New York won the NL pennant. In the 1924 World Series he averaged only .233 in a seven-game loss to the Washington Senators.