The show stars Robert Guillaume as managing editor Isaac Jaffe, Felicity Huffman as executive producer Dana Whitaker, Peter Krause as anchor Casey McCall, Josh Charles as anchor Dan Rydell, Sabrina Lloyd as senior associate producer Natalie Hurley, and Joshua Malina as associate producer Jeremy Goodwin. Regular guest stars included William H. Macy as ratings expert Sam Donovan and Brenda Strong as Sally Sasser, the producer of "West Coast Update" (a sister show on the same network as "Sports Night") and professional and romantic rival of Dana. Other notable guest stars included Paula Marshall and several who later appeared on Sorkin's "The West Wing" including Janel Moloney, Teri Polo, Ted McGinley, Lisa Edelstein, Clark Gregg, Nina Siemaszko, John DeLancie, Timothy Davis-Reed, Cress Williams, Nadia Dajani, and Spencer Garrett. In addition, Malina and Huffman also appeared in "The West Wing".