Frazier turned professional in 1965 by defeating Woody Goss by a technical knockout in the first round. He won three more fights that year, all by knockout and none going past the third round. Later that year, he was in a training accident in which he suffered an injury that left him legally blind in his left eye. During pre-fight physicals, after reading the eye chart with his right eye, when prompted to cover his other eye, Frazier switched hands but covered his left eye for a second time, and state athletic commission physicians seemed not to notice or act.