In November 1884, Sutherland was elected at a by-election as the Member of Parliament (MP) for Greenock. A Liberal, he was re-elected in 1885, but when the Liberals split over Irish Home Rule he joined the breakaway Liberal Unionist Party. He was re-elected as a Liberal Unionist in 1886, but lost the seat at the 1892 general election. However, he was reinstated when his opponent was unseated on petition, and held the seat until he stood down at the 1900 general election.