During the summer, Neuner admitted struggling for motivation for the upcoming season, having won every title in the sport at only 23 years old. However, she vowed to continue her career at least until the 2012 world championships in Ruhpolding. In December 2010 she suffered from a cold, missing the season's first World Cup in Östersund for the second year in a row. She started the 2010–11 season in Hochfilzen, where she managed two seventh-place finishes, and was part of the winning German relay team. At the third stop of the season in Pokljuka, she won the sprint race in spite of two shooting errors, claiming her 20th career victory.