Caroline continued her astronomical work after William's death in 1822. She worked to verify and confirm his findings as well as putting together catalogues of nebulae. Towards the end of her life, she arranged two-and-a-half thousand nebulae and star clusters into zones of similar polar distances. She did this so that her nephew, John, could re-examine them systematically. Eventually, this list was enlarged and renamed the "New General Catalogue". In 1828, she was awarded the Gold Medal of the Royal Astronomical Society for her work.