The Canadian Patient Safety Institute (CPSI, ) was developed in 2003 after consultations among Canadian healthcare professional organizations, provincial and territorial ministries of health and Health Canada. An independent non-profit corporation, the CPSI promotes solutions and collaboration among governments and stakeholders to improve patient safety, and has a five-year mandate. Areas of improvement are education, system innovation, communication, regulatory affairs and research. Together with the Institute For Safe Medication Practices Canada and Saskatchewan Health, a Canadian Root Cause Analysis Framework is offered to healthcare organizations to analyze the contributing factors that led to a critical incident or close call.