Williams had his best game as a pro against the New Orleans Saints in Week 9 of the 2007 season, making six catches for 128 yards and one touchdown. His best professional season to date was in 2007, where he had 38 catches for 629 yards (an average of 16.6 yards per catch) and 10 touchdowns (more than twice his career total prior to 2007). In a game against the Oakland Raiders in Week 16, he broke the Jaguars' single season receiving touchdown record, with ten scores, record previously held by the retired Jimmy Smith.