On November 22, 1935, it took off from Alameda, California in an attempt to deliver the first airmail cargo across the Pacific Ocean. Although its inaugural flight plan called for the "China Clipper" to fly over the San Francisco–Oakland Bay Bridge (still under construction at the time), upon take-off the pilot realized the plane would not clear the structure, and was forced to fly narrowly under instead. On November 29, the airplane reached its destination, Manila, after traveling via Honolulu, Midway Island, Wake Island, and Sumay, Guam, and delivered over 110,000 pieces of mail. The crew for this flight included Edwin C. Musick as pilot and Fred Noonan as navigator.