The game preserves the isometric view of "Syndicate", while adding rotation and pitch controls over that view. The player commands four agents (or acolytes, when playing as the "Church"), either singly or in groups, to complete a series of globally-located missions, the objectives for which include assassinating a specific target, or stealing a specific object. Although the general mission structure remains consistent when playing as either "EuroCorp" or the "Church", they are made distinctive by differences in the pre-mission briefings which are delivered to the player in the form of a fictional email system.