In 1964 Hardin made the painting "Medicine Talk" for her first major solo exhibition at Enchanted Mesa. While with her father in 1968 in Bogotá, Colombia, she began painting in earnest and had a successful show at the American Embassy, where she sold 27 paintings. Since her reputation in the United States was tied with her mother's success, she had not been sure the degree to which she had success based upon her own merit. In Colombia her success was based on her talent alone.