She addressed an organisation for the voting rights of women called Women's Reform Club in Pretoria and further joined the council of Europeans and Bantu's. Maxeke was elected as the president of the Women's missionary society. Maxeke participated with protests related to low wages at Witwatersrand and eventually joined the Industrial and Commercial Workers Union in 1920. Maxeke’s leadership skills led her to be call by the South African Ministry of Education to testify before several government commissions in Johannesburg on matters concerning African education— a first for any African of any gender. She continued to be involved in many multiracial groups fighting against the Apartheid System and for women's rights.