Ann Margaret Bickford (née Garrett) (1810 – 24 January 1877) was determined to carry on her husband's business. With five children under the age of ten, she enrolled the help of a retired pharmacist Mr Paxton to 'hold the fort' until more permanent help could be found. She soon engaged qualified chemists Edwin Page and Robert Hutton, and "with their able assistance" carried on the business for 14 years. (Mr Hutton was to open a pharmacy of his own at 76 Rundle Street in 1863.) On 29 May 1865 the shop shifted yet again – to 19 Hindley Street, later the site of Tattersall's Hotel.