Upper Pine Bottom Run's virgin white pines were all clearcut, but in 1925 the Department of Forests and Waters reported "thrifty young growth has now taken in its place". In the 1920s chestnut blight killed almost all the American chestnut trees in the Tiadaghton State Forest, and oak trees suffered from oak leaf tier moths in the 1950s and oak leaf roller moths in 1967. Gypsy moths defoliated the state forest between 1978 and 1982. The surrounding state forest is "dominated by mixed oak forests", along with hardwoods such as ash, beech, birch, cherry, and maple, as well as hemlock and pine. The Pine Creek Gorge is home to over 225 species of wildflowers, plants and trees, 40 species of mammals, 245 species of birds, and 26 species of fish. Common animals include deer, squirrels, bear, eagles, wild turkey, and ravens.