Ralph Edward Flanders (September 28, 1880 – February 19, 1970) was an American mechanical engineer, industrialist and politician who served as a Republican U.S. Senator from the state of Vermont. He grew up on subsistence farms in Vermont and Rhode Island and was an apprentice machinist and draftsman before training as a mechanical engineer. He spent five years in New York City as an editor for a machine tool magazine. After moving back to Vermont, he managed and then became president of a successful machine tool company. Flanders used his experience as an industrialist to advise state and national commissions in Vermont, New England and Washington, D.C. on industrial and economic policy. He was president of the Boston Federal Reserve Bank for two years before being elected U.S. Senator from Vermont.