Academically, the school is modeled after the North Carolina School of Science and Mathematics. Studies focus on mathematics, computer science, science, and humanities. All courses are taught at the Honors level or above. ASMSA offers approximately 50 courses for university credit through a partnership with the University of Arkansas at Fort Smith and other advanced high school courses for elective credit. ASMSA graduates finish their two-year experience, having earned an average of 50 college credit hours. ASMSA has an arts program, which was added in 2004 by the state legislature. Though not yet at the depth of the school's STEM-based programs, investment has been made in recent years to enhance the studio and digital arts experiences. Since 2015, the school has added three full-time faculty members in studio art and music to achieve this goal.