Throughout times Nădlac, a castle with wooden and soil fortification, was invaded by the Tartars, was held by János Hunyadi, and was donated to the commanding officers Gyorgy Istvan and Dmitar Jakšić who laid the foundation of a new fortification. It was also ravaged several times by the Turks, and was razed to the ground by the rebels led by György Dózsa. It was, however, rebuilt every time. In 1685 the town was conquered by the Austrian royal army and was integrated in the border disposition of the Mureș valley.