The anime adaptation of "Bobobo-bo Bo-bobo" is directed by Hiroki Shibata, produced by Toei Animation and ran for 76 episodes from November 8, 2003, to October 29, 2005, on TV Asahi. The first opening theme for episodes 1 to 32 is "Wild Challenger" by Jindou and the second opening theme for episode 33 onwards is by Ulfuls. The first ending theme for episodes 1 to 19 is by Mani Laba, the second ending theme for episodes 20 to 32 is by FREENOTE and the third ending theme for episode 33 onwards is "H.P.S.J." by mihimaru GT.