In the January 16, 1903 issue of the "Dallas Morning News", an article in Amusements critiqued Williams' performance in "When We Were Twenty-One": "Miss Kathlyn Williams, who assumed the role of Phyllis, is an actress of rare ability, attractiveness, and grace of delivery". Williams began her career with Selig Polyscope Company in Chicago, Illinois and made her first film in 1908 under the direction of Francis Boggs. By 1910, she was transferred to the company's Los Angeles film studio. Williams played "Cherry Malotte" in the first movie based upon Rex Beach's 1906 novel "The Spoilers" in 1914.