Drawing from her childhood experience with the Salvation Army, in 1927 McPherson opened a commissary at Angelus Temple offering food, clothing, and blankets. She became active in creating soup kitchens, free clinics, and other charitable activities during the Great Depression, and fed an estimated 1.5 million. Volunteer workers filled commissary baskets with food and other items, as well as Foursquare Gospel literature. When the government shut down the free school-lunch program, McPherson took it over. Her giving "alleviated suffering on an epic scale".