The main characters in the "Blue Drop: Tenshitachi no Gikyoku" anime are , voiced by Akiko Yajima (Japanese) and Hilary Haag (English), and , voiced by Miyuki Sawashiro (Japanese) and Monica Rial (English). After the incident on the island, Mari is taken in by her grandmother, who has her educated by tutors at home. Eventually, knowing that she herself may not have long to live, her grandmother enrolls Mari in Kaihō Academy. Enrolled against her will, she misses her home, and can not hide her distress and anger. Hagino, on the other hand, is calm and collected, an excellent student, and an all-round athlete. Despite being very popular among her classmates, however, she never shows emotion, surrounding herself with an aura of mystery.