Granger got her start in the entertainment industry when she won a beauty contest at the age of 13 at Silver Beach Summer Resort near Houston. Her budding figure and confident stage presence were perfect for studios that made comedy shorts. In 1930 her father took her to producer Hal Roach, who was then testing talent for his upcoming comedy series, The Boy Friends. Granger’s natural comedy timing got her the job immediately and she was placed under contract to Hal Roach Studios. She became a charter member of the two-reel-comedy community, appearing opposite many major comedians at Roach, Mack Sennett, Educational Pictures, Columbia Pictures, and RKO Radio Pictures. Among her famous credits are "Hog Wild" with Laurel & Hardy, "The Dentist" with W.C. Fields, "Punch Drunks" and "Termites of 1938" with The Three Stooges. Granger also appeared with Andy Clyde, Charley Chase, Edgar Kennedy, Harry Langdon, Gus Schilling & Richard Lane, and Joe DeRita, as well as on live television with Abbott & Costello. Granger is best remembered as the sarcastic, suspicious wife in Leon Errol’s series of two-reelers for RKO.