In 2013, Macdonald started a video podcast, "Norm Macdonald Live", on which he interviewed comedians and other celebrities. In 2018, he released "Norm Macdonald Has a Show", a Netflix talk show with a similar premise to his podcast. Throughout his career, Macdonald has appeared in numerous movies and been a guest on talk shows such as "Conan", "Late Night with David Letterman", and "The Howard Stern Show". He has also worked as a voice actor, notably on the animated show "Mike Tyson Mysteries".