The main storyline tells of the player showing up at Gregory House, where Gregory the manager himself meets the player and tells him about a previous guest known only as "that man". Gregory further explains that the guests delusional beliefs has gotten far too powerful, and that he is able to take over the hotel, turn it into a dungeon, and distort the surreal world around it. Gregory wants the player to help him and the other guests on a quest to take back Gregory House and defeat the man, who is mad with delusional power. The main quest also takes the player and company outside the hotel to the cactus sibling's homeland, (seen in volume 3) which is called Cactus Land. The quest also takes the player & co. to Roulette boy's casino.