In 2011 spring training, Morse led the Grapefruit League with nine home runs with 18 RBI. He started the 2011 regular season in a left field platoon with Laynce Nix, but slumped on offense and was relegated mostly to pinch hitting by May. However, on May 22, 2011, Morse moved to first base when Adam LaRoche's season was ended by injury. In his first four games at first base, Morse hit three home runs with eight RBI. From May 22 to July 5, Morse had 13 home runs and 35 RBI, the most in the majors in that span of time, earning him consideration with four others for the National League's final roster spot in the 2011 All-Star Game. Morse was named to "Sports Illustrated"'s "All-Underrated Team".