There are sister school locations in St. Louis, MO and Washington, D.C., as well as monasteries in other areas throughout the U.S. The school is coeducational from preschool through grade 5, but becomes single-gender in sixth grade. Prior to the 2017-18 school year, it was co-ed from preschool to sixth grade, and all-girls from seventh grade onwards. To coincide with this change, Saint Thomas Academy added its inaugural (all-boys) sixth grade. Visitation is the only all-girls Catholic secondary school in Minnesota.