In 1952 Vyvyan joined the roster of principal sopranos at the Sadler's Wells Opera, making a triumphant debut with the company as Konstanze in Wolfgang Amadeus Mozart's "Die Entführung aus dem Serail". She returned to that house later in the season to portray Donna Anna in "Don Giovanni". On 8 June 1953 she made her Royal Opera, London debut as Lady Penelope Rich in the world premiere of Britten's "Gloriana", a production organised by the EOG. She sang in another EOG production for her debut at La Fenice on 14 September 1954; this time The Governess in the premiere of Britten's "The Turn of the Screw".