In 2007, Cooke took the Geelong World Cup and the Ronde van Vlaanderen, the first two races on the 2007 UCI Women's Road World Cup. These early season wins led to her setting a new record in the UCI's women's world road race rankings for the gap between the first and second ranked cyclists. She also won the Trofeo Alfredo Binda for a second time, the Tour of Geelong, stage 2 of the GP Costa Etrusca and defended her Grande Boucle title.