Before moving to Hollywood, Dru met and married popular singer Dick Haymes in 1941. She was 19 years old. The couple had three children: Richard Ralph Haymes (born July 24, 1942), Helen Joanna Haymes (born May 13, 1944) and Barbara Nugent Haymes (born September 19, 1947). Divorced from Haymes in 1949, Dru married "Red River" and "All the King's Men" co-star John Ireland less than a month later. The pair divorced in 1957. She had no children from her marriage to Ireland, or subsequent two marriages.