Although Disston's engineered canals aided water transport and steamboat traffic in Florida, he was ultimately unsuccessful in draining the Kissimmee River floodplain or lowering the surface water around Lake Okeechobee and in the Everglades. He was forced to sell much of his investments at a fraction of their original costs. However, his land purchase primed Florida's economy and allowed railroad magnates Henry Flagler and Henry Plant to build rail lines down the east coast of Florida, and another joining the west coast, which directly led to the domination of the tourist and citrus industries in Florida. Disston's immediate impact was in the Philadelphia area, where he was active in Republican politics and a philanthropist, but his legacy is often associated with the draining and development of Florida.