He was promoted to Titular Archbishop of Seleucia Pieria on 24 June 1926 and was appointed Apostolic Nuncio to Venezuela four days later. He was next named Apostolic Nuncio to Peru on 26 July 1936. In addition, he was responsible for the affairs of the church in Ecuador, which did not have diplomatic relations with the Holy See for nearly forty years. He was named nuncio to Ecuador on 25 July 1937 once the Ecuadorian government and the Holy See established diplomatic relations.