During the night of 5–6 October 1533, the new church was largely gutted by fire, however Lancelot II of Ursel managed to save the building. The completion of the second tower was therefore delayed, which led to its ultimate postponement. Moreover, the church only became the cathedral of the bishopric of Antwerp in 1559 but lost this title again from 1801 to 1961, following the Concordat of 1801. During the Iconoclasm of 20 August 1566 (part of the Beeldenstorm at the start of the Eighty Years' War), Protestants destroyed a large part of the cathedral interior. The eye-witness Richard Clough, a Welsh Protestant merchant then in Antwerp, wrote that the cathedral: "looked like a hell, with above 10,000 torches burning, and such a noise as if heaven and earth had got together, with falling of images and beating down of costly works, such sort that the spoil was so great that a man could not well pass through the church. So that in fine I cannot write you in x sheets of paper the strange sight I saw there, organs and all destroyed."