In 2007 Weatherspoon was the head coach of the Westchester Phantoms of the American Basketball Association. In April 2008 she joined the coaching staff of the Lady Techsters of Louisiana Tech. On February 9, 2009, she was promoted to interim head coach to replace former head coach Chris Long. April 2, 2009 saw Louisiana Tech shed the interim label and name Teresa head women's basketball coach. In 2011, she was voted in by fans as one of the Top 15 players in the fifteen-year history of the WNBA. In 2016, Weatherspoon was named in the WNBA Top 20@20. On September 26, 2019, Weatherspoon was named two-way player development coach for the New Orleans Pelicans. Weatherspoon was later promoted to a full-time assistant coach for the Pelicans on November 16, 2020.