Elfriede Lohse-Wächtler grew up in a middle-class family, but left at the age of 16 to study at the Royal Arts School Dresden from 1915 to 1918 (fashion, then applied graphics). From 1916 to 1919, she also attended drawing and painting courses at the Dresden Art Academy. She came into contact with the Dresden Secession Group 1919 and became part of the circle of friends around Otto Dix, Otto Griebel, and Conrad Felixmüller. Renting part of the studio of the latter near the Dresden city center she made a living with batiks, postcards and illustrations.