Hatshepsut was the daughter and only child of Thutmose I and his primary wife, Ahmose. Her husband Thutmose II was the son of Thutmose I and a secondary wife who was named Mutnofret, who carried the title King's daughter and was probably a child of Ahmose I. Hatshepsut and Thutmose II had a daughter named Neferure. After having their daughter, Hatshepsut could not bear any more children. Thutmose II with Iset, a secondary wife, would father Thutmose III, who would succeed Hatshepsut as pharaoh.