Disfigurement, whether caused by a benign or malignant condition, often leads to severe psychosocial problems such as negative body image; depression; difficulties in one's social, sexual, and professional lives; prejudice; and intolerance. This is partly due to how the individual copes with looking 'visibly different', though the extent of the disfigurement rarely correlates with the degree of distress the sufferer feels. An additional factor which affects sufferers of a disfigurement is the reaction they get from other people. The general population responds to people with a disfigurement with less trust and respect, and often try to avoid making contact or having to look at the disfigurement. Disfigurements affecting visible areas, such as the face, arms, and hands, are thought to present greater difficulty for sufferers to cope with than do other disfigurements.