"Zombiepowder." follows a teenaged boy named Elwood Shepherd, who joins with mysterious criminals Gamma Akutabi and C.T. Smith in their search for the Rings of the Dead. These rings are a group of legendary artifacts with the power to resurrect the dead and grant immortality to anyone who collects 12 of them. The series has a Weird West setting which mixes a background of sparsely populated frontier settlements and gunslinger aesthetics with modern conveniences, occult magic, supernatural martial arts, and mad science. The trio travel from town to town in this world, fighting other criminals for possession of the Rings of the Dead. The protagonists obtain three of the rings in the course of the story, but due to the series' cancellation, the eventual success or failure of their quest is unknown.