Her first clay tournament was the home tournament Prague Open. Strýcová reached the quarterfinals, falling to Samantha Stosur in a tight three set match. She played Madrid next, where she upset then No. 3, Angelique Kerber in straight sets, then lost to Madison Keys in the second round. Her next tournament was Rome, where she reached the quarterfinals with wins over Karin Knapp, Heather Watson, and Eugenie Bouchard. In quarterfinals, she faced Madison Keys, and lost in a tight three setter, having been up two breaks in the first set. Yet, this was her best result in Rome. Having not won a main draw match in a decade in Rolland Garros, she reached the third round with wins over compatriot Lucie Hradecká and Polona Hercog. In the third round she faced then No. 2, Agnieszka Radwańska, and lost in three sets.