In 41 BCE, Herod and his brother Phasael were named as tetrarchs by the Roman leader Mark Antony. They were placed in this role to support Hyrcanus II. Later, Antigonus, Hyrcanus' nephew, took the throne from his uncle with the help of the Parthians. Herod fled to Rome to plead with the Romans to restore Hyrcanus II to power. The Romans had a special interest in Judea because their general Pompey the Great had conquered Jerusalem in 63 BCE, thus placing the region in the Roman sphere of influence. In Rome, Herod was unexpectedly appointed King of the Jews by the Roman Senate. Josephus puts this in the year of the consulship of Calvinus and Pollio (40 BCE), but Appian places it in 39 BCE. Herod went back to Judea to win his kingdom from Antigonus. Toward the end of the campaign against Antigonus, Herod married the granddaughter of Hyrcanus II, Mariamne (known as Mariamne I), who was also a niece of Antigonus. Herod did this in an attempt to secure his claim to the throne and gain some Jewish favor. However, Herod already had a wife, Doris, and a young son, Antipater, and chose therefore to banish Doris and her child.