The current Iowa 150 was created shortly after Iowa 17 supplanted the former Iowa 150 in the west-central part of the state. The new Iowa 150 replaced Iowa 11, which stretched from Calmar to Cedar Rapids via Independence, in its entirety. Through Cedar Rapids, the highway entered from the north along Center Point Road NE. It turned west onto US 151 and Iowa 64 along 1st Avenue E near Coe College. It turned south onto 10th Street SE on which it traveled for a few blocks to the corner of Mount Vernon Road and 8th Avenue SE, which carried US 30 east and west, respectively.