Entering his fifth season with the Predators, Weber continued his stellar record. At the February Olympic break, Weber accumulated 35 points in 59 games for the Predators. He also established a strong leadership role and willingness to defend his teammates, highlighted by three consecutive games in March 2010 in which he fought opposing players. Weber's offensive production slowed after the Olympic break and he finished the season with 43 points in 78 games played. Despite a decrease in offence from the previous season, Weber was a Norris Trophy candidate for the third consecutive year, receiving one first place vote and 96 voting points to finish as the sixth runner-up behind winner Duncan Keith (1,096 points). Weber also received a single fifth-place vote, tying for 23rd with six other players in Hart Memorial Trophy voting, and was the seventh-ranked defenceman in NHL All-Star Team voting with 83 voting points.