Cal played at home the next week against the Portland State Vikings, a Division I Football Championship opponent that was the last team scheduled on the Bears' 2006 schedule. The Vikings were 2–0 going into this game at California Memorial Stadium before a crowd of 61,082. Portland State scored a field goal on their opening drive, but the Bears responded with three more touchdowns before the first quarter ended, one coming from a Daymeion Hughes 30-yard interception. In the second quarter, Marshawn Lynch posted a 71-yard touchdown run, and another touchdown midway through the third quarter put the Bears put 35–3. Portland State scored two quick touchdowns before the half ended, but the half closed with Cal receiver DeSean Jackson scoring on a 27-yard pass. Cal substituted many of its roster into the game in the second half, and neither team scored in the second half, as the Bears won 42–16, bringing their record to 2–1.