Neuner continued the winter with mixed results in January 2011. She reached the podium in the sprints of Oberhof and Ruhpolding, coming in second and third respectively. In the relay in Oberhof, Neuner was part of Germany's team coming in sixth place, the team's worst result since 2005. She also had her worst personal result in 13 months, finishing in 16th place in the Ruhpolding individual race, which ended her streak of 24 consecutive top ten finishes (including 15 podiums and 6 wins). At the World Cup in Antholz, Neuner again struggled with illness. She only participated in the concluding mass start, coming in 6th place.