Polyynes such as falcarindiol can be found in Apiaceae vegetables like carrot, celery, fennel, parsley and parsnip where they show cytotoxic activities. Aliphatic C17-polyynes of the falcarinol type were described to act as metabolic modulators and are studied as potential health-promoting nutraceuticals. Falcarindiol is the main compound responsible for bitterness in carrots, and is the most active among several polyynes with potential anticancer activity found in Devil's club ("Oplopanax horridus"). Other polyynes from plants include oenanthotoxin and cicutoxin, which are poisons found in water dropwort ("Oenanthe spp.") and water hemlock ("Cicuta spp.").