On November 19, 2011, Grant faced Francois Botha for the vacant World Boxing Federation (WBF) Heavyweight title. Grant won by a 12th-round KO, having needed a KO due to being well behind on all three cards. The fight took place in Johannesburg, South Africa, the first time he had fought outside the USA. Immediately after the fight, Grant called out the Klitschko brothers who hold all of the major heavyweight titles. After an 18-month layoff, Grant defended the WBF belt against France-based Cameroonian Carlos Takam on May 24, 2013 in Noisy-le-Grand, France, losing by 8th round technical knockout.