Corculum possibly died in 141—perhaps of the plague that broke out the previous year in Rome—because his son Nasica Serapio succeeded him as pontifex maximus that year. Such a succession at the head of the Roman religion was unprecedented. However, neither Corculum's son (consul in 138), nor his grandson (consul in 111) became princeps senatus, contrary to what Diodorus and Valerius Maximus tell; although the leading role Serapio had in the opposition to Tiberius Gracchus shows that he also inherited his father's influence over the senate.