The first portion of the US 340 freeway to open was between the MD 180 interchange east of Petersville and the ramp from MD 180 west of Jefferson was opened, replacing the curvaceous old alignment at Catoctin Creek. The present alignment of US 340 opened as a four-lane divided highway from the Valley Road / Keep Tryst Road intersection in Sandy Hook east to Weverton also opened that year. The portion of the freeway between Weverton and MD 180 east of Petersville was under construction in 1964 and completed in 1965. MD 180 was assigned to old US 340 from Sandy Hook to west of Jefferson in 1965. By 1967, MD 180 became a split route; MD 180A was assigned to Keep Tryst Road between its intersections with US 340 in Sandy Hook and Weverton.