Trlicek had a very solid spring training in 1992, and started the season with the Toronto Blue Jays, working as a middle reliever. He made his major league debut on April 8, 1992 at Tiger Stadium. Trlicek pitched 2/3 of an inning, allowing 2 runs in the Blue Jays 10-9 victory over the Detroit Tigers. He would then pitch a scoreless inning against the New York Yankees at SkyDome in Toronto on April 14, however, he was sent to the Syracuse Chiefs of the International League for the remainder of the season after that appearance. In Syracuse, Trlicek had a 1-1 record with a 4.40 ERA in 35 games.