Hood married Jane Reynolds (1791–1846). on 5 May 1824. They settled at 2 Robert Street, Adelphi, London. Their first child died at birth, but a daughter, Frances Freeling Broderip (1830–1878), was born soon after they moved to Winchmore Hill, and after they had then moved in 1832 to Lake House, Wanstead, a son, Tom Hood (1835–1874), was also born. Both children took up in Hood's profession: Frances became a children's writer and Tom a humorist and playwright, and they later collaborated in collecting and publishing their father's work. Although constantly worried about money and health, the Hoods were a devoted, affectionate family, as "Memorials of Thomas Hood" (1860), based on his letters and compiled by his children, testifies.