The Tsuji-Wacker Oxidation oxidizes terminal olefin to the corresponding methyl ketone under the Wacker process condition. Almost identical to that of Wacker Process, the proposed catalytic cycle(Figure 1) begins with complexation of PdCl2 and two chloride anions to PdCl4, which then undergoes subsequent ligand exchange of two chloride ligand for water and alkene to form Pd(Cl2)(H2O)(alkene) complex. A water molecule then attacks the olefin regioselectively through an outer sphere mechanism in a Markovnikov fashion, to form the more thermodynamically stable Pd(Cl2)(OH)(-CH2-CHOH-R) complex. Dissociation of a chloride ligand to the three coordinate palladium complex promotes β-hydride elimination, then subsequent 1,2-hydride insertion generates Pd(Cl2)(OH)(-CHOHR-CH3) complex. This undergoes β-hydride elimination to release the ketone, and subsequent reductive elimination produces HCl, water, and palladium(0). Finally palladium(0) is reoxidized to PdCl2 with two equivalents of Cu(II)Cl2, which in turn can be reoxidized by O2.