The hospital was built in 1942, and opened on Washington's Birthday in 1943 to care for the wounded of World War II. It became the largest military hospital in the United States. Eventually, the hospital had well over 3,000 patients and over 100 separate buildings. One feature of the hospital was its design of primarily two story buildings, interconnected by corridors. There were very long ramps leading from one floor to the other, to facilitate movement of wheelchairs and gurneys. The architecture was designed by Matthew Bookler.