Cats that are particularly sensitive to their environment require a strict routine with minimal environmental changes. For instance, owners can inadvertently stress their cats out with their own emotional displays or changes in their routines. The use of simulated feline facial pheromone can reduce the activation of the sympathetic nervous system and reduce stress through a sense of familiarity. Lastly, anti-inflammatory drugs such as onsior or meloxicam may be prescribed to reduce swelling and pain during an acute flare-up of cystitis. Amitriptyline, an antidepressant, has also shown some benefits but needs further research.