The Congregation for the Doctrine of the Faith (CDF; ) is the oldest among the nine congregations of the Roman Curia, seated at the Palace of the Holy Office in Rome. It was founded to defend the church from heresy; today, it is the body responsible for promulgating and defending Catholic doctrine. Formerly known as the Supreme Sacred Congregation of the Roman and Universal Inquisition, it is informally known in many Catholic countries as the Holy Office (), and between 1908 and 1965 was officially known as the Supreme Sacred Congregation of the Holy Office.