Barry married Effi Slaughter, his third wife, just after announcing his candidacy for mayor in 1978. The couple had one son, Marion Christopher Barry, who died of a drug overdose on August 14, 2016. The Barrys separated in November 1990, soon after he was caught on videotape smoking crack cocaine with an ex-model and propositioning her for sex. They divorced in 1993, but she returned to Washington and supported him in his successful bid for a city council seat in 2004. Effi died on September 6, 2007, after an 18-month battle with acute myeloid leukemia.