On 24 March 2017, "Port Royal" returned to Pearl Harbor after a 212-day independent deployment to the Arabian Sea, Persian Gulf, Gulf of Oman, Red Sea, Gulf of Aden, South China Sea, Western Pacific, and Indian Ocean. During this time the ship conducted joint maritime security exercises with South East Asia partners, theatre anti-submarine operations, joint counterterrorism/smuggling exercises, Pacific presence operations in the South China Sea, 5th Fleet sector air defense, and carrier strike group operations with and . "Port Royal" also conducted straits transits, providing protection for U.S. and international commerce and projecting sea control in the vicinity of Yemen and Somalia.