Shortly after his graduation from high school, Superboy takes his adoptive parents on a holiday in the Caribbean where they contract a rare tropical disease. Though Superboy tries valiantly to save Martha and Jonathan, nothing cures their illness. With Clark by her side, Martha passes away. Just before he dies, Jonathan makes Clark promise to use his powers only for good. In mourning, Clark buries his parents. Shortly thereafter, Superboy leaves Smallville, though not before throwing the townsfolk a giant farewell party that he tops off with a giant cake. Separately, Clark departs for Metropolis to attend Metropolis University.