The route passes west of a park and pool lot and enters the town of Odessa, where the median widens to include development within it and the road curves to the northeast. In Odessa, US 13 is known as 5th Street northbound and 6th Street southbound in addition to Dupont Parkway. Through the town, the route passes homes with a few businesses, crossing DE 299. Upon leaving Odessa, the median narrows again and US 13 continues into rural areas along Dupont Parkway, passing under DE 1. The road curves north and crosses Drawyer Creek a short distance to the west of DE 1. The highway runs through a mix of farmland and residential subdivisions before it comes to an intersection with the southern terminus of DE 896 and Pole Bridge Road in Boyds Corner, with Pole Bridge Road heading east to an interchange with DE 1. Following this, US 13 passes under DE 1 again and runs through more farmland a short distance to the east of the Biddles Corner toll plaza on DE 1. As the highway approaches St. Georges, a partial interchange provides access to and from the northbound direction of DE 1; the ramp from southbound DE 1 connects to US 13 by way of Lorewood Grove Road while there is a direct ramp from US 13 to northbound DE 1 at the Port Penn Road intersection in Biddles Corner that merges with the ramp from northbound US 301 to northbound DE 1. A right-in/right-out interchange connects to South Main Street northbound and Lorewood Grove Road southbound to provide access to South St. Georges.