At the European Parliament election, 1999, Evans was elected as MEP for Wales, and he was re-elected at the 2004 Euro-elections. He was Leader of the Conservatives in the European Parliament from 2001 until 2004. From 2004 to 2009 he was President of the European Parliament Delegation for relations with the U.S. Congress and Co Chairman of the Transatlantic Legislators Dialogue. Following the decision of President Bush and Angela Merkel to set up the Transatlantic Economic Council, he became Chairman of the Council's Advisory Board. In August 2007, he was selected to fight the highly marginal seat of Cardiff North in the 2010 general election. Evans stood down from the European Parliament at the 2009 elections and was succeeded by Kay Swinburne, Evans subsequently won the Cardiff North seat with a majority of 194 votes. He became chairman of the All Party Parliamentary Group on Wholesale Financial Markets and Services and of the All-Party Parliamentary group on Insurance and Financial services. He was also Chairman of the All Party Group for Mutuals and sponsored the Mutuals (Deferred Shares) Act 2015 through the House of Commons. He was MP for Cardiff North from May 2010 until March 2015.