Mizanin signed with WWE in 2004, and debuted on the main roster in 2006. He has won the WWE Championship twice, the Intercontinental Championship eight times, the United States Championship twice, the World Tag Team Championship twice, the Raw Tag Team Championship four times, and the SmackDown Tag Team Championship twice, giving him 20 overall championships in WWE. As a result, he became WWE's 25th Triple Crown Champion and 14th Grand Slam Champion, as well as the only wrestler to accomplish the latter twice under the revised 2015 format. He also won the 2010 Money in the Bank ladder match. Among WWE's most prolific pay-per-view event performers, Mizanin headlined WrestleMania XXVII in 2011, and was ranked No. 1 on "Pro Wrestling Illustrated"s annual "PWI 500" list that same year.