Clemson opened its season with 3 consecutive home game victories. This is the first time that there have been 3 consecutive home games to open the season since 2003 and only the eighth time since 1923. Clemson played against the 2006 Atlantic Coast Conference champion Wake Forest in November and played the 2006 Mid-American Conference champion Central Michigan for the first time. The 2007 season saw Clemson meeting Louisiana-Monroe and Central Michigan for the first time, with Clemson beating both of them.