Calhoun led the Huskies to another national championship in 2004, at the conclusion of a season that saw UConn start and complete the year as the number one team in the nation. UConn standouts Emeka Okafor and Ben Gordon were selected No. 2 and No. 3 in the NBA Draft, respectively. Calhoun now holds a 35–12 record with UConn in NCAA tournament play including 6–1 in the Final Four. They lost in the first round for the first time on March 21, 2008 in overtime to San Diego.