In 1908 he was sent to America by the Socialist Revolutionaries and the Sejmists. With the help of the following he had attracted among the radical Jewish intellectuals during his previous visit, Zhitlowsky founded a publishing house that issued a new monthly, "Dos Naye Leben" (The New Life). Under his editorship, the journal exercised great influence on Yiddish culture, including the development of free socialist thought, and became an organ of modern Yiddish literature; for the six years it existed (until 1914), "Dos Naye Leben" was a spiritual home of many Jewish publicists and scientists.