The plague theory, which suggests a severe epidemic outbreak might have hit the heavily populated Angkor and contributed to the fall of the empire, has been reconsidered. By the 14th century, the Black Death had affected Asia, as the plague first appeared in China around 1330 and reached Europe around 1345. Most seaports along the line of travel from China to Europe felt the impact of the disease, which might have had a severe impact on life throughout Southeast Asia. Possible diseases include bubonic plague, smallpox and malaria.