The first relocation of US 15 north of Frederick occurred at Tuscarora Creek between 1950 and 1952. Construction on Washington National Pike, which is now I-270, began in 1950. The highway's cloverleaf interchange with US 15, which would serve as the freeway's northern terminus for several years, was built in 1952 and 1953. The adjacent portion of US 15 from Evergreen Point south to Lime Kiln was relocated, reconstructed, and widened in 1951 and 1952. In 1954, US 240 was moved to Washington National Pike; the old alignment became US 240 Alternate and then MD 355 in 1956. The section of freeway from US 15 to the Frederick Freeway was built between 1954 and 1956 concurrent with the first section of the Frederick Freeway. The original interchange between the Frederick Freeway and Washington National Pike included two ramps between the north–south and east–west portions of the Frederick Freeway.