The first European settlers were mostly ethnic French Canadians, who created their first settlement in Missouri at present-day Ste. Genevieve, about an hour south of St. Louis. They had migrated about 1750 from the Illinois Country. They came from colonial villages on the east side of the Mississippi River, where soils were becoming exhausted, and there was insufficient river bottom land for the growing population. The early Missouri settlements included many enslaved Africans and Native Americans, and slave labor was central to both commercial agriculture and the fur trade. Sainte-Geneviève became a thriving agricultural center, producing enough surplus wheat, corn and tobacco to ship tons of grain annually downriver to Lower Louisiana for trade. Grain production in the Illinois Country was critical to the survival of Lower Louisiana and especially the city of New Orleans.