In 2001, she also played the epic character Sita in Zee TV's "Ramayan". In 2006, Irani co-produced the show "Thodi Si Zameen Thoda Sa Aasmaan" under her banner Ugraya Entertainment and co-produced by Balaji Telefilms. She also played the lead role of Uma in it. In 2007, she produced the TV serial "Virrudh" for Sony TV and also portrayed the lead character of Vasudha in it. She also produced "Mere Apne" for 9X and portrayed the protagonist alongside Vinod Khanna. She also acted in a supporting role in Zee TV's "Teen Bahuraaniyaan".