Cardinal Driscoll (Peter Weller), who is introduced at the beginning of the film and who is tipped to be the next Pope, arrives in Rome from the US and gives Alex a special dagger. According to a fragment of parchment Alex and Thomas find among Dominic's books, the dagger is to be plunged into the Sin Eater while reciting a text in Aramaic. Alex and Thomas take these instructions to mean that the dagger and incantation will kill the Sin Eater and they begin hunting for the Sin Eater and the remainder of the parchment instructions.