In January 2007, Innes left "ER" in the middle of the thirteenth season, becoming the longest-serving cast member in the show's history, but Noah Wyle appeared in four more episodes than her. From 2008 to 2009, Innes returned to "ER" during its 15th and final season for two episodes including the series finale "And in the End...". Innes' films include the blockbuster science fiction disaster film "Deep Impact" (1998) and the comedy "Can't Stop Dancing" (1999) with her former "ER" co-star Noah Wyle.