In 1992, Walker played the female leading role opposite Jean-Claude Van Damme in the science-fiction action film "Universal Soldier" directed by Roland Emmerich. Later that year, she played Sheila Kelley's grouchy roommate in the Cameron Crowe romantic comedy "Singles". Her first star-billed role was in the 1994 thriller "When the Bough Breaks". In 1995, she had supporting roles in Sandra Bullock's box-office hit "While You Were Sleeping", and Andy García's flop "Steal Big Steal Little". The following year, Walker co-starred alongside Shaquille O'Neal in the fantasy comedy film, "Kazaam".