Zambrotta signed a four-year contract with Barça, where he joined Juventus teammate Lilian Thuram, who also left the club. During his seven-year tenure with Juve, Zambrotta formed one of the best teams in the world at the time, as well as one of the world's most feared defenses. He formed defensive partnerships with the likes of Mark Iuliano, Paolo Montero, Ciro Ferrara, Thuram, Jonathan Zebina, Nicola Legrottaglie, Alessandro Birindelli, Fabio Cannavaro and Giorgio Chiellini. Overall, he made 297 appearances for Juventus, scoring ten goals.