On 5 December 1926 Roman Catholic Archbishop James Duhig laid the foundation stone for St Columban's College at "Highlands" at 451 Sandgate Road (). The school officially opened on Sunday 29 January 1928 as a school for boys operated by the Christian Brothers. In 1985 the Christian Brothers passed the management of the college to the Brisbane Diocese. This triggered a number of changes, a phasing out the primary school to focus on secondary schooling. In 1996 the school accepted enrolments from girls and in 1997 the school relocated to Caboolture. The Albion site has been redeveloped as The Clayfield retirement village but three heritage buildings have been retained on the site: Highlands, O'Driscoll Hall and Whytecliffe.