In 2001, she won the role of Breanna Barnes in the UPN series "One on One" (2001–2006). During the run of "One on One", Pratt also voiced Penny Proud, the lead character in the Disney Channel animated series "The Proud Family". She also voiced the character for "The Proud Family Movie" in 2005. In addition to television roles, Pratt has appeared in several feature films, including "Love & Basketball" (2000) and "Fat Albert" (2004). She played Maya Dolittle in "Dr. Dolittle" (1998) and "Dr. Dolittle 2" (2001), both of which starred Eddie Murphy. She reprised her role as Maya Dolittle (now the lead character) in the direct-to-DVD releases of "Dr. Dolittle 3" (2006), ' (2008), and ' (2009).