Between 1928 and 1932, Ziadeh suffered a series of personal losses, beginning with the death of her parents, a number of her friends, and above all Khalil Gibran. She fell into a deep depression and returned to Lebanon where her relatives placed her in a psychiatric hospital to gain control over her estate. Nawal El Saadawi alleges that Ziadeh was sent to the hospital for expressing feminist sentiments. Ziadeh was profoundly humiliated and incensed by this decision; she eventually recovered and left after a medical report proved that she was of sound mental health. She returned to Cairo where she died on October 17, 1941.