Markham came to Cambridge from Atchison, Kansas to pursue an education at the recently founded women's college later named Radcliffe. Upon arriving in Cambridge, she found a home with Colonel Thomas Wentworth Higginson on Buckingham Street, to whom she is said to have become "virtually an elder daughter" (59). After she began teaching in a neighbor's home, another neighbor, Mrs. Richard H. Dana, offered to build a schoolhouse and living quarters nearby, where the school began with 12 students. That schoolhouse continues to be part of BB&N's Lower School campus to this day.