From 1991 to 1999, Bybee worked as a professor of law at the Paul M. Hebert Law Center at Louisiana State University. In 1999, Bybee left to work as a professor of law at William S. Boyd School of Law at the University of Nevada, Las Vegas until his appointment as Assistant Attorney General in 2001. Later he returned to teach constitutional law as a Senior Fellow in Constitutional Law at Boyd Law School after his appointment to the bench (2005-present).