In late 1924 or 1925, Spielrein left Moscow. She and her daughter rejoined her husband Pavel in Rostov-on-Don. As well as probably being disillusioned by her experience in Moscow, Spielrein may have been impelled to return because her husband by now was in a relationship with a Ukrainian woman, Olga Snetkova (born Aksyuk), and they now had a daughter, Nina. Pavel returned to his wife, and their second daughter Eva was born in 1926. For at least the next decade, Spielrein continued to work actively as a pediatrician, carrying out further research, lecturing on psychoanalysis, and publishing in the west until 1931. In 1929 she presented a vigorous defense of Freud and psychoanalysis at a congress of psychiatry and neuropathology in Rostov, possibly the last person to mount such a defense at a time when psychoanalysis was on the point of being proscribed in Russia.