The presents material linked to the transition from earlier settlers to the Early Acheulean. Archaeological sites related to the Middle Acheulean in the current-day region lie on the Campo de Calatrava as well as in the source of the Villanueva river, the Guadiana catchment area and the Segura catchment area. The Upper Acheulean sites are mostly located within the limits of the current-day province of Ciudad Real, substantially increasing in number and territorial spread across the region for the ensuing Middle Paleolithic. The Upper Paleolithic in the region presents instances of the art of the Upper Paleolithic in the Serranía del Alto Tajo and the Upper Júcar. There are instances of Cardium pottery in Caudete from the Early Neolithic.