East of Mecklenburg, NY 79 passes into Tompkins County and the town of Enfield. As Mecklenburg Road, it heads eastward through rolling farmland and hills toward the city of Ithaca. It intersects NY 327 at Enfield Corners in this stretch. As NY 79 approaches downtown Ithaca, it becomes Hector Street and curves to the northeast, then to the southeast as it descends to Cayuga Lake. At the base of the hill, the route crosses the Cayuga Inlet and enters downtown, where it splits into a one-way couplet along State Street (eastbound) and Seneca Street (westbound). NY 79 eastbound shifts one block south at Fulton Street (NY 13, NY 34, and NY 96 southbound) to use Green Street. The one-way couplet ends one block east of Aurora Street at the "Tuning Fork" as Green and Seneca streets merge into East State Street, recently double-named Martin Luther King Jr. Street. NY 79 follows State Street southeastward through eastern Ithaca into the town of Ithaca. The portions of NY 79 between the Ithaca west city line and NY 13A, between NY 89/96 and Meadow Street (NY 13/34/96 northbound) and between Green Street and the Ithaca east city line are maintained by the city.