Already an immensely popular character actor and movie star of several Westerns, James Best appeared on the sixth episode of "Laramie." Best played a worried young man who demanded that Jess Harper help save a young man dying of a snake bite. Fuller and Best had a great connection and since the writers loved him from his first appearance, Best later did two additional guest spots on "Laramie" with Fuller, long before landing a starring role in the popular action-comedy satire, "The Dukes of Hazzard", in the 1980s and later, two movies, in 1997 and 2000.