Neeskens, a native of Heemstede, started his career at RCH Heemstede in 1968, before being spotted by Rinus Michels and signed for Ajax in 1970. The youngster impressed at right-back, playing in that position for Ajax in the 1971 European Cup Final win against Panathinaikos. During the 1971–72 season, Neeskens took up more of a central midfield role, in support of Johan Cruyff. He adapted well to his new central midfield role because he was a tireless runner, had great technical skills and scored his fair share of goals. Ajax completed a hat-trick of European Cup wins between 1971 and 1973, and Neeskens moved on to FC Barcelona in 1974 to join Cruyff and Michels. There he was nicknamed "Johan Segon" ("Johan the Second").