At the University of Chicago, Yang first spent twenty months working in an accelerator lab, but he later found he was not as good as an experimentalist and switched back to theory. His doctoral thesis was about angular distribution in nuclear reactions. Later he worked on particle phenomenology; a well-known work was the Fermi–Yang model treating pion meson as a bound nucleon–antinucleon pair. In 1956, he and Tsung Dao (T.D.) Lee proposed that in the weak interaction the parity symmetry was not conserved, Chien-shiung Wu's team at the National Bureau of Standards in Washington experimentally verified the theory. Yang and Lee received the 1957 Nobel Prize in Physics for their parity violation theory, but unfortunately stereotypes prevented Wu from being awarded, despite the revolutionary change it would bring to particle physics. Yang has also worked on neutrino theory with Tsung Dao (T.D.) Lee, 1957, 1959, CT nonconservation (with Tsung Dao (T.D.) Lee and R. Oheme, 1957), electromagnetic interaction of vector mesons (with Tsung Dao (T.D.) Lee, 1962), CP nonconservation (with Wu Tai-Tsun, 1964).