After leaving Gila Bend, I-8 takes a southeastern course as it passes through the Sonoran Desert National Monument. Exiting the national monument grounds, the highway continues on an easterly bearing to a junction with SR 84, a highway that parallels I-8 to the north and goes through Casa Grande, while I-8 passes to the south of both Stanfield and Casa Grande. I-8 reaches its eastern terminus southeast of Casa Grande Mountain Park at an interchange with I-10, which continues south (eastbound) to Tucson, and north (westbound) to Phoenix.