Transiting the Panama Canal on 2 October, "Wrangell" arrived at Pearl Harbor on the 19th, where she loaded additional ammunition. She soon sailed for Southeast Asian waters and, operating out of Subic Bay, Philippines, and making seven stints to the "line", provided ammunition for ships operating on both the Yankee and Dixie Stations into the spring of 1966. During her five months in WestPac, "Wrangell" transferred over 6,800 tons of ammunition in 74 underway replenishments. In addition, besides ammunition, the ship delivered fleet freight, mail, transient personnel, movies, and, on two occasions, fresh water and provisions. Arriving back at Subic Bay after her seventh mission on the "line", "Wrangell" departed Philippine waters on 2 May.