Clarke appeared on the daytime soap opera "Days of Our Lives" as Faith Taylor (where her father was a senior cast member), and starred on "Soldier of Fortune, Inc." for both of its seasons. She also guest starred on ' as the Amazon chieftain Velasca, "Firefly" as the brothel madam Nandi, "Charmed" as the Siren, and has had six appearances on ' where she played the dominatrix, Lady Heather. She also appeared in the "Seinfeld" episode "The Muffin Tops", playing Jerry's girlfriend who likes anything hairless. She also played a lead role in the 1993 horror film "Return of the Living Dead 3".