Historically, the region has had other universities, but these no longer exist. The present University of Castilla–La Mancha uses one of the buildings of the Royal University of Toledo (1485–1807). Other former universities in the region were the Royal and Pontifical University of Our Lady of Rosario in Almagro (1550–1807) and the University of San Antonio de Porta Coeli in Sigüenza founded in the 15th century by Cardinal Pedro González de Mendoza and, like the others, closed in the Napoleonic era.