Gephardt was born in St. Louis, Missouri, the son of Loreen Estelle (née Cassell) and Louis Andrew Gephardt, a Teamster milkman; part of his ancestry is German. He graduated from the former Southwest High School in 1958. Gephardt is an Eagle Scout and recipient of the Distinguished Eagle Scout Award from the Boy Scouts of America. He earned his B.S. at Northwestern University in 1962 where he was president of Beta Theta Pi, the student senate, and his freshman class. He earned his J.D. at the University of Michigan Law School in 1965.