Route 54 continues east from US 13 as East Line Road through farmland and scattered residences along the state line. At Brittingham Road, maintenance jurisdiction returns to MDSHA. Around the intersection with Whitesville Road, Route 54 dips into Maryland for a short distance, then returns to following the state line until the intersection with MD 353 (Gumboro Road) and DE 26 (Millsboro Highway). At that intersection, Route 54 turns northeast and joins DE 26 in a concurrency. From this point, the highway remains in Delaware. A short distance north of the state line, DE 30 (Whitesville Road) joins the concurrency. In Gumboro, DE 26 and DE 30 continue north while Route 54 turns east onto Cypress Road. Route 54 crosses Bald Cypress Branch and the Pocomoke River, then passes through the Great Cypress Swamp. After crossing the swamp, the highway intersects US 113 on the west edge of the town of Selbyville.