Anglo-Chinese School (Barker Road) () is a secondary school of the Anglo-Chinese School family located at the Barker Road campus, Singapore. It offers the GCE 'O' Level Course for its students from Sec 1 to Sec 4/5. Students may then move on to Anglo-Chinese Junior College or Anglo-Chinese School (Independent). It has provided opportunities for its feeder students to continue with an ACS Education at a secondary level. ACS was also the first school in Singapore to have a flower named after it, the Ascocenda Anglo-Chinese School orchid, a hybrid created by the school to mark its 116th Founder's Day on 1 March 2002. ACS has many partner schools such as Anglo-Chinese School (Junior) and Anglo Chinese Junior College. The school is close to Newton MRT station.