Byzantines, Genoese, and Ottomans fought over this strategic fortification for years. It was first conquered by Ottoman forces in 1305, but retaken by the Byzantines shortly thereafter. Bayezid I took the castle again in 1391 while preparing for his siege of Constantinople. It was used as his field headquarters during the construction of Anadoluhisarı, one of the more important castles for the siege. In 1399 the Byzantines attempted to take back Yoros Castle. The attack failed, but the village of Anadolu Kavağı was burned to the ground. The Ottomans held the fortress from 1391–1414, losing it to the Genoese in 1414. The forty-year Genoese occupation lent the castle its moniker of Genoese Castle.