The street was listed on maps of the area since at least 1755. The "Bend" in Mulberry, where the street changes direction from southeast to northwest to a northerly direction, was made to avoid the wetlands surrounding the Collect Pond. During the period of the American Revolution, Mulberry Street was usually referred to as "Slaughter-house Street", named for the slaughterhouse of Nicholas Bayard on what is now the southwest corner of Mulberry and Bayard Streets, which was located there until the summer of 1784, when it was ordered to be removed to Corlaer's Hook.