He is known for his roles in comedy films. One of his best performances in his later years were "Naukar Biwi Ka", "Sharaabi" (1984) and "Chameli Ki Shaadi", where he played a role that was pivotal for the movie. His role in Gopi with Dilip Kumar is considered best in terms of acting. Critics still think he gave better performance in tragic scenes in front of Dilip Kumar. Once Dilip Kumar revealed the fact, "I was only afraid once in my acting career and it was during Gopi when Om Prakashji's performance overshadowed mine".