Jerry Vines was born in Carrollton, Georgia near Atlanta in 1937. Before attending seminary, he pastored his first church, Centralhatchee Baptist Church, at the age of 16. He was educated at Mercer University, New Orleans Baptist Theological Seminary, and Luther Rice University before pastoring in churches in Alabama and Georgia. While pastor of Dauphin Way Baptist Church in Mobile, Alabama he was elected President of the Alabama Pastors' Conference. He relocated to Jacksonville in 1982 to co-pastor the First Baptist Church with Homer G. Lindsay Jr.