Against medical advice, Studd first visited the Belgian Congo in 1913 in the company of Alfred Buxton, and he established four mission stations in an area then inhabited by eight different tribes. Studd returned to England when Priscilla fell ill, but when he returned to the Congo in 1916 she had recovered sufficiently to undertake the expansion of the mission into the Worldwide Evangelisation Crusade with workers in South America, Central Asia and the Middle East as well as Africa. Supported by his wife's work at home, Studd built up an extensive missionary outreach based on his centre at Ibambi in Budu territory. Priscilla made a short visit to the Congo in 1928. That was the last time they met; she died the following year. Studd was joined in his work by his daughter Pauline and son-in-law Norman Grubb, and his grandson Noel Grubb, who died on his first birthday, is buried at Nala, Democratic Republic of the Congo. Studd's daughter Edith married Buxton.