Keothavong then competed in two Premier tournaments, the BNP Paribas Open in Indian Wells and Sony Ericsson Open in Miami. Keothavong crashed out in round one in both tournaments. To Anna Chakvetadze of Russia in three sets, after winning the first to continue her losing record against her in Indian Wells. And under sad circumstances in Miami, as she lost in straight sets to Tamira Paszek and said afterwards "Frankly tennis didn’t seem that important today" after receiving news before the match that her grandmother had died.