Following this, Berne worked at a hospital in the London suburb of Tottenham as a residency, before returning to Australia in 1895. On 9 January 1895, Berne registered to practice as a doctor with the Medical Board of New South Wales. Previous woman to register in Australia included Dr Constance Stone- Victoria and Dr Margaret Amelia Corlis (Department of Public Instruction Sydney, 13 May 1892 - New South Wales Medical Board Sydney, 11 May 1892 - 1,766). She opened a practice in Macquarie Street, Sydney the same year. Her sister Eugenie came to live with her, and persuaded her to take tests due to her continuing symptoms despite the better Australian weather.