The right half of the ventromedial prefrontal cortex was associated with regulating the interaction of cognition and affect in the production of empathic responses. Hedonic (pleasure) responses were also associations to orbitofrontal cortex activity level by Morten Kringelbach. This finding contributes findings suggesting ventromedial prefrontal cortex being associated with preference judgement, possibly assigning the ventromedial prefrontal cortex a key role in constructing one's self. fMRI scans have found that the vmPFC is active when people think about themselves. There are cultural differences in the use of this region based on cultural differences in self-perception. Chinese subjects who think of the self in relation to the community have been found to utilize the vmPFC when thinking about their mothers, whereas American subjects do not.