Pompey took over entire Cilicia and organized it as a Roman province in 64BC. Adana was of relatively minor importance during the Roman's influential period, while nearby Tarsus was the metropolis of the area. During the era of Pompey, the city was used as a prison for the pirates of Cilicia. The Sarus bridge was built in the early 2nd century, and for several centuries thereafter, the city was a on a Roman military road leading to the East. After the permanent split of the Roman Empire in 395 AD, the area became a part of the Byzantine Empire, and was probably developed during the time of Julian the Apostate. With the construction of large bridges, roads, government buildings, irrigation and plantation, Adana and Cilicia became the most developed and important trade centers of the region.