Clarke, in 1924, embarked upon a career as a solo and ensemble performer in London, after first completing a world tour in 1922–23. In 1927 she helped form the English Ensemble, a piano quartet that included herself, Marjorie Hayward, Kathleen Long and May Mukle. She also performed on several recordings in the 1920s and 1930s, and participated in BBC music broadcasts. Her compositional output greatly decreased during this period. However, she continued to perform, participating in the Paris Colonial Exhibition in 1931 as part of the English Ensemble. Between 1927 and 1933 she was romantically involved with the British baritone John Goss, who was eight years her junior and married at the time. He had premiered several of her mature songs, two of which were dedicated to him, "June Twilight" and "The Seal Man". Her "Tiger, Tiger", finished at the time the relationship was ending, proved to be her last composition for solo voice until the early 1940s.