During World War II, Papon served as a senior police official in the Vichy régime. He was the second official in the Bordeaux region (the secretary-general of the prefecture of Gironde) and the supervisor of its Service for Jewish Questions. With authority over Jewish affairs, Papon regularly collaborated with Nazi Germany's SS Corps, which was responsible for the extermination of Jews. Under his command, about 1,560 Jews were deported. Most were sent directly to the camp of Mérignac and then they were transported to Drancy internment camp, near Paris, and finally to Auschwitz or other concentration camps for extermination.