In one episode of "Jack Van Impe Presents", which aired during the week of June 19, 2006, Van Impe informed his audience that he had undergone two total knee replacements in early 2006. He gave thanks to God for his recovery and for leading him to the "wonderful surgeon" who performed the operation. Subsequent to the problems with his knees, Van Impe suffered from cancer, a severe sepsis attack, and blood loss resulting from stomach ulcers which he attributed to his NSAID arthritis medication. On the episode which aired during the week of May 31, 2015, Jack Van Impe was absent from the program, and Rexella Van Impe explained that he had been hospitalized for triple by-pass heart surgery. Carl Baugh co-hosted the program until Van Impe's return to his weekly show on October 3, 2015.