Weld was elected Governor of Massachusetts in 1990. In the 1994 election, he was reelected by the largest margin of victory in Massachusetts history. In 1996, he was the Republican nominee for the United States Senate in Massachusetts, losing to Democratic incumbent John Kerry. Weld resigned as governor in 1997 to focus on his nomination by President Bill Clinton to serve as United States Ambassador to Mexico; due to opposition by socially conservative Senate Foreign Relations committee Chairman Jesse Helms, he was denied a hearing before the Foreign Relations committee and withdrew his nomination. After moving to New York in 2000, Weld sought the Republican nomination for Governor of New York in the 2006 election; when the Republican Party instead endorsed John Faso, Weld withdrew from the race.