Like most rural counties throughout Missouri, voters in Ste. Genevieve County generally adhere to socially and culturally conservative principles but are more moderate or populist on economic issues. Its character is similar to those of Yellow Dog Democratic counties in the South. In 2004, Missourians voted on a constitutional amendment to define marriage as the union between a man and a woman—it overwhelmingly passed Ste. Genevieve County with 75.25 percent of the vote. The initiative passed the state with 71 percent of support from voters as Missouri became the first state to ban same-sex marriage. In 2006, Missourians voted on a constitutional amendment to fund and legalize embryonic stem cell research in the state—it failed in Ste. Genevieve County with 56.22 percent voting against the measure. The initiative narrowly passed the state with 51 percent of support from voters as Missouri became one of the first states in the nation to approve embryonic stem cell research. Despite Ste. Genevieve County's longstanding tradition of supporting socially conservative platforms, voters in the county have a penchant for advancing populist causes like increasing the minimum wage. In 2006, Missourians voted on a proposition (Proposition B) to increase the minimum wage in the state to $6.50 an hour—it passed Ste. Genevieve County with 79.26 percent of the vote. The proposition strongly passed every single county in Missouri with 78.99 percent voting in favor as the minimum wage was increased to $6.50 an hour in the state. During the same election, voters in five other states also strongly approved increases in the minimum wage.