Negroponte speaks five languages (English, French, Greek, Spanish, and Vietnamese). He is the elder brother of Nicholas Negroponte, founder of the Massachusetts Institute of Technology's Media Lab and of the One Laptop per Child project. His brother Michel Negroponte is an Emmy Award-winning filmmaker, and his other brother, George Negroponte, is an artist and was President of the Drawing Center from 2002 to 2007. Negroponte and his wife, Diana Mary Villiers (b. August 14, 1947), have five adopted children, Marina, Alexandra, John, George and Sophia, all of whom were adopted from Honduras. On February 16, 2020 it was reported that daughter Sophia was arrested on the charge of first-degree murder for the stabbing death of a man. The Negropontes were married on December 14, 1971.