Tod was unable to secure the pro-Union renomination in 1863, losing it to another War Democrat, John Brough, who enjoyed greater popularity among Ohioans and more actively supported the anti-slavery direction the Northern war effort had by then taken. President Abraham Lincoln then offered Tod the post of U.S. Secretary of the Treasury, telling an aide, "He is my friend, with a big head full of brains... he made a good governor, and has made a fortune for himself". Tod, knowing he was not radical enough for Republicans in the United States Senate and in fragile health, declined the appointment. Tod died of a stroke in 1868, at the age of 63, leaving a widow and seven children. He was a Republican Presidential elector in 1868 for Grant/Colfax. He died before the meeting of electors, and was replaced by G. V. Dorsey.