He suffered from depression for many years, stemming from the death of his brother and the failure of his marriages. In 2008 Carluccio attempted suicide with a pair of scissors, but survived following the intervention of his personal assistant. At the time of the incident, the media were informed that he had had an accident with a bread knife. Carluccio later described his suicide attempt as "liberating", feeling that "from that moment on, my mind changed" and stating that his subsequent admittance to the Priory clinic made him "take stock of my life, and appreciate all the good in it".