The Indiana portion of I-70 begins at the Illinois state line west of Terre Haute. Heading east, I-70 crosses the Wabash River soon after entering the state. US 40 travels concurrent with I-70 briefly before breaking off and traveling north of the interstate into the center of the city. The interstate crosses through the south side of Terre Haute, where it has an interchange with US 41/US 150. Just outside the city to the east, I-70 passes near Terre Haute Regional Airport before continuing onward to the east-northeast through rural lands towards Indianapolis. This stretch of I-70 does not have any interchanges with any significant cities until it reaches the Indianapolis metropolitan area, but it does pass within proximity of Greencastle.