In the Australian Open, traditionally his best grand slam event, he began with a straight-sets win over 48th-ranked Frenchman Julien Benneteau and followed that up by ousting 16th-seed Robin Söderling in four sets and 23rd-seed Mardy Fish in straight sets to set up a fourth-round clash with third-seed and defending champion Novak Djokovic. The fourth round encounter with Djokovic started poorly for Baghdatis, going down 1–6 in the first set. The second set went into a tie-breaker, which Baghdatis lost 1–7. The third set went into another tie-breaker, but Baghdatis earned three set points, lost two of them on his own serve, and then took the tie-breaker on Djokovic's serve. After 3 hours and nearly 20 minutes, Baghdatis was unable to come back from an early break in the first game of the last set, as he missed two break opportunities and lost 1–6, 6–7, 7–6, 2–6.