In the late 1980s, after 12 years of being with his brothers, Toño was removed from the group and began his own solo career. He debuted on April 14, 1990, in the "Roberto Clemente" Coliseum of Puerto Rico. He went on to become the most popular merengue singer with some of his albums reaching diamond status. Toño's song "Alegría" was played at Comerica Park in Detroit, Michigan whenever former Detroit Tigers utility infielder Omar Infante came to bat. Toño Rosario has the best selling merengue album of all time, Quiero Volver a Empezar, which was his debut on WEA International in 1996.