M-153 starts as an interchange with M-14's exit 10 in Superior Township east of Ann Arbor. The highway starts as an expressway curving southeasterly to meet Ford Road near the curve eastward in the expressway at Frains Lake Road, a gravel road northeast of the unincorporated community of Dixboro. Ford Road continues west of here to end at Plymouth Road south of the M-14 freeway, and east of this location, M-153 follows Ford Road through wooded, partially developed terrain to the Washtenaw–Wayne county line at Napier Road. Near the county line are farms until Ford Road reaches residential subdivisions at Ridge Road in Canton Township. At the east edge of the township, Ford Road meets I-275 at exit 25 before passing into Westland between Lotz and Hix roads.