Early spectral classification of the nuclei of the LIRGs that host hydroxyl megamasers indicated that the properties of LIRGs that host hydroxyl megamasers cannot be distinguished from the overall population of LIRGs. Roughly one third of megamaser hosts are classified as starburst galaxies, one quarter are classified as Seyfert 2 galaxies, and the remainder are classified as low-ionization nuclear emission-line regions, or LINERs. The optical properties of hydroxyl megamaser hosts and non-hosts are not significantly different. Recent infrared observations using the Spitzer Space Telescope are, however, able to distinguish hydroxyl megamaser hosts galaxies from non-masing LIRGs, as 10–25% of hydroxyl megamaser hosts show evidence for an active galactic nucleus, compared to 50–95% for non-masing LIRGs.