Flanagan has donated her time and talent to perform at charity and fundraising events such as Comedians Unite for the Premier's Disaster Relief Appeal to help victims of Queensland's 2011 floods, and she donated half of the profits from her 2013 Bundaberg show to the Queensland Red Cross Flood Appeal. In 2009, Flanagan performed in Sydney at the Jerry Lewis 'Laugh For Life' Charity Concert to support Muscular Dystrophy Foundation Australia (MDFA) in their fund raising and awareness efforts to fight the devastating muscle wasting disease. Flanagan appeared alongside fellow Australian comedians Julia Morris, Paul McDermott, Mikey Robins, Peter Berner, Fiona O'Loughlin, and Tom Gleeson in the fundraising gig at Sydney's Enmore Theatre. In 2003 while Flanagan was living and working in the UK, she joined some of the UK's top comedians for a charity fundraiser hosted by fellow comedian Steve Coogan. Flanagan appeared alongside Ross Noble, Johnny Vegas, Simon Pegg, Tim Vine, Lee Mack, Matt Lucas, Rob Brydon and Mark Williams in Coogan's 'Drugathon 2' to raise funds for the Chemical Dependency Centre (now named Action on Addiction) and RAPt (The Rehabilitation of Prisoners Trust).