Hopkins has portrayed characters in several television shows including a "Specialist" in "Birds of Prey", "Lester" in "Crossing Jordan", and has had appearances in "Dragnet", "Charmed", ', "My Name Is Earl", "Point Pleasant" and "Ghost Whisperer". Hopkins has also starred in an episode of ' as "Donny Drummer" and had a recurring role on "Lost" as Charlie's older brother and former heroin addict, "Liam Pace". He also made appearances in two episodes of Big Love as "Ken Byington" and in an episode of "The 4400" as "Nick Crowley". Hopkins plays musicians in several series, appearing as a rock star in "The 4400" and "Lost", and as a promising musician on "Ghost Whisperer".