The serial nature of the work influenced the storyline structure, allowing for numerous sub-plots, a large cast, and an extended middle sequence. This allowed for a focus on destructive imagery and afforded Otomo the chance to portray a strong sense of movement. He also established a well-realized science fiction setting, and his art evoked a strong sense of emotion within both character and reader. The work has no consistent main character, but Kaneda and Tetsuo are featured the most prominently throughout.