On 25 February 1943, "Saracen" departed for Malta, then left Malta on 16 March to conduct a patrol north of Sicily. Two days later, she sighted two German landing craft, but did not attack them due to their shallow draft, which would have caused torpedoes to run under. On 20 March "Saracen" sighted an Italian convoy of two merchant ships, four destroyers, and sixteen aircraft, but she was detected by one of the escorting ships' sonar, which foiled the attack. On 1 April, the boat returned to Algiers, ending her patrol.