In January 2017, it was announced that McEntire would star and produce a Southern drama series for ABC titled "Red Blooded". It was reported in May that ABC ultimately turned down the show, so it moved to being shopped around to other networks. In January 2018, Reba was chosen to portray KFC's first female Colonel Sanders. The commercials ran through the end of April 2018. In 2020, McEntire launched a podcast titled "Living & Learning" hosted by herself and her former "Reba" co-star Melissa Peterman.