The town was founded in 1832. A post office was opened at Orono in July 1852 (postmaster: Joseph Tucker), when the village contained about 200 residents, and was named after Orono, Maine since the landscape seemed similar. The name for the post office is said to have been selected in 1852 when a visitor from Maine suggested Orono— the name of a town near Bangor, Maine. Declared a police village in 1854, the village remained small but vibrant. Significant to the village's growth in the opening decades of the twentieth century was the arrival of the Canadian Northern Ontario Railway in 1911. Farming was, and remains, an important economic activity in the area. Many motorists stopped in the town on their way from Lindsay to Newcastle before the 35/115 was built. The population is approximately 1800.