2006 saw mass die-offs from VHS in Lake Erie, the St. Clair River, the Detroit River, and the St. Lawrence River, which connects the Great Lakes to the Atlantic Ocean. VHS was further detected in the Niagara River, which connects Lake Erie to Lake Ontario. It was also found in a walleye die-off in the landlocked inland Conesus Lake, the westernmost of the Finger Lakes in western New York state. This was the first case in the region outside waters contiguously connected to the Great Lakes.