In early 41, Caligula was assassinated as a result of a conspiracy by officers of the Praetorian Guard, senators, and courtiers. The conspirators' attempt to use the opportunity to restore the Roman Republic was thwarted, however. On the day of the assassination of Caligula, the Praetorians declared Caligula's uncle, Claudius, the next Roman emperor. Although the Julio-Claudian dynasty continued to rule the empire until the fall of his nephew Nero in 68, Caligula's death marked the official end of the Julii Caesares in the male line.