The story takes place during the fifth to tenth years of the boy's life, as he comes to know his new home in a remote mountain hollow. Granpa runs a small moonshine operation during Prohibition. The grandparents and visitors to the hollow expose Little Tree to supposed Cherokee ways and "mountain people" values. Encounters with outsiders, including "the law," "politicians," "guv'mint," city "slickers," and "Christians" of various types add to Little Tree's lessons, each phrased and repeated in catchy ways. (One of the devices the book uses frequently is to end paragraphs with short statements of opinion starting with the word 'which,' such as "Which is reasonable.")