Antioch was called "the cradle of Christianity" as a result of its longevity and the pivotal role that it played in the emergence of both Hellenistic Judaism and early Christianity. The Christian New Testament asserts that the name "Christian" first emerged in Antioch. It was one of the four cities of Seleucis of Syria, and its residents were known as "Antiochenes". The city may have had up to 250,000 people during Augustan times, but it declined to relative insignificance during the Middle Ages because of warfare, repeated earthquakes, and a change in trade routes, which no longer passed through Antioch from the far east following the Mongol invasions and conquests.