In 1990 the band signed a major-label contract with Epic Records. In 1991, the band released their fifth album, and first for a major label, "Uncle Anesthesia". The album was produced by Terry Date and Soundgarden vocalist Chris Cornell and included the single "Bed of Roses", which gained considerable airtime on alternative rock radio stations and peaked at # 23 on the modern rock tracks. The single was the first Screaming Trees release to chart. Although "Uncle Anesthesia" sold better than their previous efforts, the band remained a cult act.