Louis Menand settled in the village in 1842 and established an important horticultural business. He at first rented land that later became the Home for Aged Men, and then in 1847 bought 11 acres of land where the Albany-Watervliet Turnpike (today Broadway) met the road going to Ireland's Corners (today Loudonville), that road is today called Menand Road. When the Albany and Northern Railroad was built in 1856 it established a stop in present-day Menands and named the stop "Menand's Crossing" since Menand was the only landowner in that area at the time. When the Albany and Northern became part of the Delaware and Hudson a station was built at that stop and called "Menand's Station". In the early 1920s rumors circulated that the city of Albany was going to annex the area and so on August 23, 1924 a vote was taken and the village of Menands was incorporated by a vote of 167 for and 47 against, the population of the new village at that time being 1,272 people. The boundaries of the new village were those of the 15th School District of the town of Colonie. The original boundaries did not include what are now the Sage Hill Lane, Sky Hollow, and Roost Country Estates, those were annexed later and continue to be in the North Colonie Central School District.