At the Battle of Sarus in April 625, Heraclius defeated the Sasanian Shahrbaraz forces that are stationed at the east bank of the river, after a fearless charge across the Justinian bridge (now Taşköprü). Byzantines defended the region from encroaching Islamic Caliphates throughout the 7th century CE, but it was finally conquered in 704 by the Umayyad Caliph Abd al-Malik. During Umayyad rule, Cilicia became a no man's land frontier between Byzantine Christian and Arab Muslim forces. In 746, profiting by the unstable conditions in the Umayyad Caliphate, Byzantine Emperor Constantine V took control of Adana in 746. Abbasid Caliphate took over the rule of the region from Byzantine after Al-Mansur's inauguration to caliph in 756. With the Abbasid rule, Muslims for the first time started settling in Cilicia. Abandoned for more than 50 years, Adana was garrisoned and re-settled from 758 to 760. To form a Thughūr on the Byzantine frontier, Cilicia was colonized with the Turkic Sayābija tribe from Khorasan. The city had seen rapid economic and cultural growth during the reign of Harun al-Rashid and Al-Amin. Abbasid rule of the city continued for more than two centuries, and the Byzantines retook control of Adana in 965. The city became part of the Seleucia theme. After the defeat at the Battle of Manzikert in 1071, the emperor Romanos IV Diogenes was removed from reign by a coup. He then gathered a troop to regain his power, though got defeated and had to retreat his troop to Adana. He was forced to surrender by the garrison in Adana upon receiving assurances of his personal safety.