In the years 1613 through 1620, Hasekura headed the Keichō Embassy (), a diplomatic mission to Pope Paul V. He visited New Spain and various other ports-of-call in Europe on the way. On the return trip, Hasekura and his companions re-traced their route across New Spain in 1619, sailing from Acapulco for Manila, and then sailing north to Japan in 1620. He is considered the first Japanese ambassador in the Americas and in Spain, despite other less well-known and less well-documented missions preceding his mission.