As a person of multiple talents, Siddiqui was also a refined poet, musician, and a painter. In August 1924, he held his first international exhibition of paintings in Frankfurt. Later in 1927, his works of art were exhibited at the Uzielli Gallery, Frankfurt. During his stay in Germany, he also translated Rainer Maria Rilke's poetry into Urdu, which was published in the journal of Jamia Millia Islamia. Though, his passion for arts was superseded by the enthusiasm in scientific research, he continued to patronise arts and culture. In 1966, he was at the forefront for setting up the Central Institute of Arts and Crafts in Karachi. He also compiled a selection of poetry of Mir Taqi Mir into "Intekhab-e-Meer". In 1983, he published a portfolio collection of charcoal drawings from 1920 to 1950s.