John made extensive missionary journeys into the interior of China, sometimes traveling over 5,000 km. He was among the first to begin Christian missionary work in the provinces of Hubei (Hupeh), Hunan, and Sichuan (Szechwan). He set up schools, hospitals and training colleges, with a permanent base at Hankou (now part of Wuhan city) in Hubei. In 1861 he went from Shanghai through the provinces of central China, and he later claimed that with his colleagues he had established over 100 mission stations in Hubei and Hunan. In July of that year he had moved to Hankou, which remained his base until his final departure from China in 1912 - although in 1863 he was in neighbouring Wuchang District (now part of Wuhan city), and in 1867 Hanyang District (also now part of Wuhan city).