Ortelius was born on in the city of Antwerp, which was then in the Habsburg Netherlands (modern-day Belgium). The Orthellius family were originally from Augsburg, a Free imperial city of the Holy Roman Empire. In 1535, the family had fallen under suspicion of Protestantism. Following the death of Ortelius's father, his uncle Jacobus van Meteren returned from religious exile in England to take care of Ortelius. Abraham remained close to his cousin Emanuel van Meteren, who would later move to London. In 1575 he was appointed geographer to the king of Spain, Philip II, on the recommendation of Arias Montanus, who vouched for his orthodoxy.