The Salmon River is a small river north of Syracuse in Upstate New York, the United States. It is a popular and economically important sportfishing destination, and the most heavily fished of New York's Lake Ontario tributaries. From its headwaters in the Tug Hill region of New York, it flows westward through two hydroelectric dams and over the Salmon River Falls before it empties into eastern Lake Ontario at Port Ontario in Oswego County. The Salmon River watershed drains approximately .