Having fully regenerated, Commissioner Dolan calls The Spirit away to a case and relates Sand's history as one of the world's great jewel thieves. While arresting her, he reveals he knows she is looking for the Golden Fleece, and she shoves him through a window, which he survives. The Spirit receives a tip on the location of the Octopus's lair but is captured while investigating. The Octopus reveals that his and Floss's experimentation led to the creation of an immortality serum. The Octopus first tested it on Colt's dead body; Colt came back to life and earned the ire of Death for escaping her clutches. Eventually, the Octopus injected himself with the serum, but he needs the blood of Heracles, a demi-god, to perfect the formula. The Spirit escapes by seducing assassin Plaster of Paris (Paz Vega), who as a parting gift turns on The Octopus. When the Spirit mentions Sand's name, she stabs him out of spite.