DuBose's sister Elizabeth DuBose (1838-1875) married John Bratton, a Winnsville doctor who had graduated from South Carolina College. He became a planter, and was commissioned as an officer in the Confederate Army. He achieved the final rank of general, and led troops in both the Eastern and Western theaters during the conflict. Afterward, Bratton became a politician, being elected to the South Carolina Senate. He was later elected as the South Carolina Comptroller and ultimately as U.S. Congressman from South Carolina.