The collapse of the Crusader States was offset by Genoa's alliance with the Byzantine Empire. As Venice's relations with the Byzantines were temporarily disrupted by the Fourth Crusade and its aftermath, Genoa was able to improve its position, taking advantage of the opportunity to expand into the Black Sea and Crimea. Internal feuds between the powerful families, the Grimaldi and Fieschi, the Doria, Spinola and others, caused much disruption, but in general the republic was run much as a business affair.