The Jovians (a non-playable race) were also descended from colonists. Unlike the other races of "Eve Online", they maintained a relatively high-functioning technological society after the collapse of the EVE wormhole and did not need to spend millennia recapitulating ancient societal developments as the others did, and while the other four major races were still grounded, Jovian history saw two major periods of spacefaring empire. They expanded outward and eventually turned to genetic engineering in order to mold themselves into a species more suited for deep-space life and long-range interstellar exploration. Genetic experimentation and manipulation were not without their drawbacks, however: by the time period in which players enter the "Eve Online" universe, millennia of human genetic manipulation have rendered the Jovians barely recognizable as human; more critically, the Jovian manipulation of their genetics has resulted in the eventually fatal "Jovian Disease," an inherited psychological disorder which, despite the best efforts of the Jovians to reverse it, has affected every individual of the Jovian race and thus crippled their civilization. Having experienced a catastrophic population decline (the Jovian societal structure is believed to be barely maintained by their immensely-advanced technological systems), the Jovians have effectively retreated to inhabit a region of space inaccessible to outsiders.