Nawab M. Ismail Khan was credited for his wisdom, sagacity, and above all his sincerity that had won him a place in the All-India Muslim League and its Working Committee. In the void of M. A. Jinnah's absence from the country to attend the famous Round Table Conference in London, the sole leadership of the Indian Muslims fell in the hands of Nawab Sahib; who was the President of the All Parties Muslim Conference. Upon M.A. Jinnah's return from London, he decided to re-organise the Muslim League. During his programmes of re-organisation, Nawab M. Ismail Khan was his closest counsellor.