US 111 continued along North George Street concurrent with PA 24. The two highways intersected the Northern Central Railway just before they crossed Codorus Creek. Just north of the creek, US 111 and PA 24 left the city of York and passed through the borough of North York along what is both I-83 Business and SR 3065. Just after leaving the borough, US 111 and PA 24 separated at what is today the intersection of US 30 and PA 181. PA 24 continued north along North George Street while US 111 veered northwest along Arsenal Road, then north onto Susquehanna Trail, which is today designated SR 4005. The U.S. Highway followed the modern course of SR 4005 north to modern PA 238 (Church Road), then followed a township road to its intersection with PA 921 (Canal Road) just north of Little Conewago Creek at Zions View.