In Week 1, against the Indianapolis Colts, Rivers threw for 333 yards, three touchdowns, and one interception in the 30–24 overtime win. In Week 2, against the Detroit Lions, Rivers completed 21 passes for 293 yards in the 13–10 loss. In Week 3, against the Houston Texans, Rivers threw for 318 yards and two touchdown passes to wide receiver Keenan Allen in the 27–20 loss. In Week 4, against the Miami Dolphins, Rivers completed 24 of 30 pass attempts for 310 yards in the 30–10 win. In Week 6, against the Pittsburgh Steelers, Rivers passed for 320 yards and two touchdowns but had two interceptions in the 24–17 loss . In the following game, a 23–20 loss to the Tennessee Titans, Rivers passed for 329 yards and two touchdowns. In Week 11, against the Kansas City Chiefs at Estadio Azteca, he passed for 353 yards and a touchdown but had four interceptions in the 24–17 loss. In Week 14, against the Jacksonville Jaguars, Rivers threw for 314 yards and three touchdowns in the 45–10 blowout win. He finished the 2019 season with 4,615 passing yards, 23 touchdowns, and 20 interceptions—which were the third most in the NFL. His 23 turnovers played a part in the Chargers' 2–9 record in contests decided by a touchdown or less, and the team ended with a 5–11 overall record. On February 10, 2020, the Chargers and Rivers mutually agreed that he would not be re-signed and would enter free agency.