After a botched attempt to steal a device from Hydra, Sandi and Outlaw convinced Deadpool to rescue Alex. Alex had been affected by the device he was supposed to steal, giving him arthritis and "the American gene" (which resulted in making him incredibly fat). This made escape physically impossible - though he would not want to miss out on the many treats and monkey chow that were being given to him as a lab specimen. Deadpool managed to free Alex with the help of Bob, Agent of HYDRA. He then asked Deadpool to run Agency X whilst he got himself back in shape, reasoning with himself that his only other alternatives were to shoot himself or eat Sandi and his business.