The Basso Della Rovere Chapel was furnished by Girolamo Basso della Rovere in the 1480s. The architecture is similar to the Chapel of the Nativity and the painted decoration is attributed to Pinturicchio and his workshop. The highlights of the chapel are the great fresco of the "Madonna and Child Enthroned with Saints Augustine, Francis, Anthony of Padua and a Holy Monk" above the altar, the "Assumption of the Virgin Mary" on the first wall and the illusionistic monochrome decoration of the pedestal with painted benches and martyrdom scenes. The original maiolica floor tiles from Deruta also survived.