In 1586, as he stayed within Osaka, a riot ensued and Yoshitsugu went to quell it personally. He slew 1,000 men to Hideyoshi's pleasure, but the gore that splattered on him led to an infection. The "Uno Mondo Nikki" and "Tamon-In Nikki", said to be the diary of the monk Eishūn, state a milder version of Yoshitsugu being ill. They report rumors of Yoshitsugu searching to receive blood from living beings within the city, a method that was believed to have cured diseases. It has also been said that he was actually sick since Shizugatake, but his symptoms did not become apparent until this time. His illness was not described in detail within historical records, yet people generally believe that he was afflicted with leprosy—due to tales from the Edo Period—or syphilis—alternate explanation due to the involvement of bodily fluids.