Luiz Adriano made his season debut against Chornomorets Odesa in the Ukrainian Super Cup as Shakhtar won 3–1, but the striker failed to get on the scoresheet. He opened his account for the season in Shakhtar's first Ukrainian Premier League fixture, scoring his side's second in the final minute of normal time in a 2–0 victory over Hoverla Uzhhorod on 14 July 2013. He scored once as Shakhtar defeated Real Sociedad 4–0 in their penultimate group match of the Champions League on 27 November 2013. He scored the game's only goal in Shakhtar's next match, a league victory over Chornomorets.