This game marked Senior day for the Gators as they played their final home game of the 2008 season in the Swamp. It also featured the retirement of Citadel graduate and UF legend George Edmondson better known as "Mr. Two Bits" to Gator fans. This was the only game of the season where the Gators faced a Division I-FCS opponent. The first meeting between these two teams took place in 1910 where the Gators defeated the Bulldogs 6–2 in Jacksonville. The most recent meeting between the two teams took place as the season opener for the 1998 season where the Gators remained undefeated against the Bulldogs, winning 49–10. Florida scored 42 points in six straight games, a record unmatched by a conference member since Vanderbilt in 1915.