The National Museum of Brazil () was Brazil's oldest scientific institution. It is located in the city of Rio de Janeiro, where it is installed in the Paço de São Cristóvão (Saint Christopher's Palace), which is inside the Quinta da Boa Vista. The main building was originally the residence of the Portuguese Royal Family between 1808 and 1821 and was later used to house the Brazilian Imperial Family between 1822 and 1889. After the monarchy was deposed, it hosted the Republican Constituent Assembly from 1889 to 1891 before being assigned to the use of the museum in 1892. The building was listed as Brazilian National Heritage in 1938 and was largely destroyed by a fire in 2018.