Kwong opened her first restaurant, "Billy Kwong", in the Sydney suburb of Surry Hills. 'Billy' in the restaurant's name derives, not from the name of a family member, but from the partnership with Sydney celebrity chef Bill Granger under which the restaurant was founded. Kwong later became the sole owner of the restaurant under the original name. The current "Billy Kwong Potts Point" is co-owned with Sydney and Hong Kong chef and restaurateur Andrew Cibej and seismologist and businessman David King.