From 11–14 June 1898 the Marines engaged Spanish forces in the land battles of the Guantánamo Bay campaign. After a series of sharp engagements, the marines routed the 500 Spanish defenders, while suffering casualties of six killed and 16 wounded. The "Panther" then withdrew to her former position with the fleet in the successful campaign at Santiago. After the destruction of the Spanish fleet, "Panther" steamed to New York, to cruise between New York, Boston, Norfolk, and Portsmouth until 20 October 1899, when she went into ordinary at Philadelphia.