Near Exit 225, US 66 diverted from I-40 southeast on Buffalo Range Road. Around southeast of the Interstate, US 66 curved east on an abandoned highway grade to rejoin the route of I-40, where Buffalo Range Road turns sharply to the southwest. US 66 proceeded to follow I-40 east for , then split off again to head straight southeast, followed by a sharp curve to the north to cross the Canyon Diablo Bridge over Canyon Diablo into Two Guns. Two Guns, now abandoned, was a popular Old West-themed tourist attraction during the height of popularity of US 66. The most popular attraction at Two Guns was the Apache Death Cave, the site where several Apache individuals were murdered by a group of Navajo individuals. Leaving Two Guns, US 66 made a broad curve to the southeast across present-day I-40 exit 230, heading away from the Interstate on an abandoned roadbed.