In August 2010, 1st Battalion, 8th Marines deployed to Musa'Qaleh and Now Zad, Afghanistan in support of Operation Enduring Freedom 10-2, Regimental Combat Team 2, First Marine Division (Forward), I Marine Expeditionary Force (Forward) Afghanistan as part of the International Security Assistance Force. The unit's performance in counter-insurgency operations in the two districts were integral in the stabilization of the region and development of Afghan National Security Forces. 1/8 suffered the loss of five Marines and one Navy Hospital Corpsman that were killed in action and numerous others wounded in action during their deployment to Helmand Province.