Harsdorf served as chair of the Senate Committee on State and Federal Relations and Information Technology and vice chair of the Committee on Agriculture, Forestry, and Higher Education. She also served as co-chair of the Joint Committee on Information Policy and Technology, and as a member of the Joint Committee on Finance. She previously served as chair of the Higher Education and Tourism Committee, as the ranking Republican on the Agriculture and Higher Education Committee, and as a member of the Commerce, Utilities, Energy and Rail Committee and the Joint Legislative Council. She was also a member of the Mississippi River Parkway Commission.