In 2007, O'Hara played the role of Dot/Marie in the Los Angeles Reprise! concert staging of "Sunday in the Park with George" and Eliza Doolittle in the New York Philharmonic's semi-staged production of "My Fair Lady" at Avery Fisher Hall. She was the voice of producer Beth Totenbag on PBS's 2008 animated series "Click and Clack's As the Wrench Turns". From 2008 to 2010, O'Hara starred as Nellie Forbush in the Broadway revival of "South Pacific" at Lincoln Center's Vivian Beaumont Theater, for which she was nominated for her third Tony Award. She took maternity leave in March 2009 and returned to the musical in October 2009.