Brežice prides itself on a rich historical and cultural heritage. The Lower Sava Valley Museum (), housed in Brežice Castle, contains archaeological and ethnological exhibits, exhibits on the Croatian and Slovenian peasant revolt, and a modern history collection. It is one of the largest regional museums in the country. A more recent landmark addition to the town is its water tower, as well as the double arches of the 527 m long iron bridge, which spans the Sava and Krka rivers.