Humans have long used the Black Moshannon area for recreational, industrial, and subsistence purposes. The Seneca tribe used it as hunting and fishing grounds. European settlers cleared some land for farming, then clear-cut the vast stands of old-growth white pine and eastern hemlock. Black Moshannon State Park rose from the ashes of a depleted forest which had been largely destroyed by wildfire in the years following the lumber era. The forests were rehabilitated by the Civilian Conservation Corps during the Great Depression in the 1930s. Many of the buildings built by the Civilian Conservation Corps stand in the park today and are protected on the list of National Register of Historic Places in three historic districts.