After the events of House of M, where almost the entire mutant population lost their powers, Laurie was one of the few who retained the mutant gene. Panic spread throughout school in the aftermath of the Decimation and, assuming he'd lost his powers too, Kevin reaches out to Laurie, withering away her arm. Shortly after this trauma, Laurie is shot and killed by a sniper working for the Reverend William Stryker. It is later revealed that Stryker had her killed because a vision from the future foretold she would be the one to single-handedly defeat his army.