On September 26, 2010, Hall recorded a season-high six combined tackles, two pass deflections, and intercepted a pass by rookie quarterback Jimmy Clausen in a 20–7 victory at the Carolina Panthers in Week 3. The following week, he recorded two solo tackles, a pass deflection, and intercepted a pass by Seneca Wallace in the Bengals' 23–20 loss at the Cleveland Browns in Week 4. Hall completed the 2010 season with 44 combined tackles (33 solo), 11 assists, and four interceptions in 16 games and 16 starts.