In 2006, Ware ended the regular season with a team-high 11.5 sacks, the most ever by a Cowboys linebacker. This total broke Anthony Dickerson's record of 10.5 from 1983. He added 73 tackles, a fumble recovery, and an interception, both returned for a touchdown. Ware was named a starter on the NFC Pro Bowl team and was also named Second-team All-Pro by The Associated Press. In Week 6 against division rival Eagles, Ware had a memorable moment with his 69-yard fumble return for his first career NFL touchdown. He recorded his first career interception against Michael Vick in a game against Atlanta Falcons and returned it for a 41-yard touchdown. Ware finished tied for ninth in the league in total sacks and Shawne Merriman led the league with 17 sacks.