In May 2019, Domenech's wife Meghan McCain appeared on "Late Night with Seth Meyers", where she and Meyers discussed McCain's assertion that Rep. Ilhan Omar was anti-Semitic. Shortly thereafter, Domenech posted a number of crude tweets targeting Meyers, calling Meyers an "untalented piece of shit" and "monumental asshole" who "only has his job because he regularly gargled Lorne Michaels’ balls." "The Daily Beast" described Domenech's behavior as him having gone "on an unhinged rant agsinst the late-night host... that was at times homophobic." Domenech later deleted his tweets and apologized for "rage tweeting".