At this point, PA 144 turns southwest to join US 220 Alt. and PA 150 turns northeast to join US 220 Alt. on Appalachian Thruway, a four-lane divided highway. The road runs along the border between Boggs Township to the north and Milesburg to the south, passing near homes and businesses. The two routes fully enter Boggs Township and become a two-lane undivided road, heading near homes and businesses and passing to the south of Bald Eagle High School. In the community of Wingate, PA 144 splits from US 220 Bus., which continues southwest concurrent with PA 504, by heading northwest onto Runville Road, passing through farmland before heading between industrial areas to the southwest and woodland to the northeast. The road heads north-northwest through forested areas with some fields and homes, passing through the communities of Runville and Gum Stump. The route continues through dense forests and becomes Snow Shoe Mountain Road, heading into rugged terrain and turning west, northeast, and northwest. PA 144 heads northwest and curves north before it enters Snow Shoe Township and passes over I-80.