Her screen credits include "All Over the Guy", in which she played Dr. Ellen Wyckoff—Dan Bucatinsky's therapist mother, "Club Paradise", "Wag the Dog", "All I Want for Christmas", "Worth Winning", "Hedwig and the Angry Inch", "Stepping Out", "The Producers", and "My Big Fat Greek Wedding", in which she portrayed Aunt Voula, a role she reprised in the small-screen adaptation, "My Big Fat Greek Life", and the 2016 sequel, "My Big Fat Greek Wedding 2". In 2006, she played a major role in the remake of "Black Christmas". She played Helaine in the 2009 breakout independent film "Breaking Upwards". In the episode titled "Pupil", she played an emergency room patient on the Showtime series, "Nurse Jackie", which was aired July 27, 2009. In 2012, she provided the voice of Penny in the "American Dad!" episode "Stan's Best Friend" and appeared in an episode of "30 Rock" titled "My Whole Life Is Thunder." Martin recently appeared in "Night at the Museum 3" and Hulu's original series, "Difficult People", starring Billy Eichner and Julie Klausner and produced by Amy Poehler. It premiered August 5, 2015. She played Prudy Pingleton on "Hairspray Live!", which aired on December 7, 2016.