Like domestic cats, Savannahs and other domestic hybrids (such as Bengals) require appropriate anesthesia based on their medical needs but do not have specific requirements. It is unclear among the veterinary community why ketamine has been listed as causing ill effects; this is not accurate. It is possible this comes from a misunderstanding of the drug and its common effects, since ketamine cannot be used alone as an anesthetic. Ketamine has been found safe for use in servals together with medetomidine and butorphanol and with the antagonist atipamezole.