Currently, there is no specific antidote to treat humans that overdose on xylazine. Hemodialysis has been suggested as a form of treatment, but is usually unfavorable due to the large volume of distribution of xylazine. In addition, due to lack of research in humans, there are no standardized screenings to determine if an overdose has occurred. The detection of xylazine in biological fluids in humans involves various screening methods, such as urine screenings, thin layer chromatography (TLC), gas chromatography mass spectrometry (GC-MS), Remedi HS Bio-Rad Laboratories, and liquid chromatography mass spectrometry (LC-MS).