Despite Villa suffering some issues on and off the field at the beginning of the season, such as the resignation of manager Martin O'Neill and a humiliating 6–0 defeat at the hands of Newcastle United, Agbonlahor defended the club and stated his intent to remain there for the long term. Agbonlahor signed a new four-and-a-half-year contract on 12 November 2010, keeping him at Villa Park until at least 2015. On 16 January 2011, he made his 200th appearance in an Aston Villa shirt in a 1–1 draw with rivals Birmingham, playing the full 90 minutes at St Andrew's. Agbonlahor scored his first goal in the Premier League since April 2010 in the 2–1 victory over Wigan Athletic on 26 January 2011 at the DW Stadium. On 16 April 2011, he scored an injury-time winner away at West Ham United. Agbonlahor was less prolific in terms of goalscoring during 2010–11 due to Aston Villa manager Gérard Houllier preferring to use him as a winger.