The Guadalupe River (Muwekma Ohlone:"Thámien Rúmmey") mainstem is an urban, northward flowing river in California whose much longer headwater creeks originate in the Santa Cruz Mountains. The river mainstem now begins on the Santa Clara Valley floor when Los Alamitos Creek exits Lake Almaden and joins Guadalupe Creek just downstream of Coleman Road in San Jose, California. From here it flows north through San Jose, where it receives Los Gatos Creek, a major tributary. The Guadalupe River serves as the eastern boundary of the City of Santa Clara and the western boundary of Alviso, and after coursing through San José, it empties into south San Francisco Bay at the Alviso Slough.