Born in Monterrey, Nuevo León, Orozco began his career in 2005 with Cobras de Ciudad Juárez who at the time were the filial team for Monterrey. After playing part of the Apertura 2005 tournament with C.F. Monterrey 1a A, he was called up to the first team. He made his professional debut on August 13, 2005, a 1-0 win over CF Atlas, earning a clean sheet in his first career start. Jonathan Orozco was also part of the squad that won the Apertura 2009 with Monterrey.