Rearing of the Neosho mucket has been successfully implemented in fish hatcheries at Chesapeake, Missouri. Captive juveniles were also found to have survived 16 months after their release into native habitats in the Fall and Verdigris Rivers in Kansas. Further, these previously captive juveniles have been the first wild young specimens to have been recorded in Kansas; whereas previous surveys of the Fall, Verdigris and Neosho Rivers in Kansas have detected only mature individuals. Captive breeding of this mussel will be important in future to restore recently degraded wild populations in the face of the species’ extensive population and range declines.