Soon Lysimachus made the fatal mistake of having his son Agathocles murdered at the say-so of his second wife, Arsinoe (282 BC). Agathocles's widow, Lysandra, fled to Seleucus, who now made war upon Lysimachus. Seleucus, after appointing his son Antiochus ruler of his Asian territories, defeated and killed Lysimachus at the Battle of Corupedium in Lydia in 281 BC, but Seleucus did not live to enjoy his triumph for long – he was almost immediately murdered by Ptolemy Ceraunus, for reasons that remain unclear.