Eudora was the site of conflict during the Bleeding Kansas Era and the American Civil War. Eudora strongly supported the Union during the Civil War, many of its men enlisted to defeat the Confederacy. William Quantrill passed through the Eudora area in 1863 on his way to Lawrence, Kansas to commit his infamous and deadly raid on the unsuspecting town. Several Eudora residents attempted to warn Lawrence of Quantrill's proximity, but two men were thrown from their horses, one of them dying as a result of his injuries. After the raid, Eudorans were quick to aid the citizens of Lawrence as they started their recovery.