Fingask Castle was badly damaged in 1745 by government troops, as the Threiplands once more supported the Jacobites in the second Jacobite rising. David Threipland (1694–1745), son of the 2nd baronet, was killed at the Battle of Prestonpans. His half-brother Dr. Stuart Threipland (1716–1805), repurchased Fingask in 1783 at a sale of forfeited land, for £12,207. He married firstly at St. Paul's, Edinburgh, in 1753, Jannet, daughter of David Sinclair of Southdun, Caithness, and secondly at St. Paul's Edinburgh, in 1761, Jannet daughter of Richard Murray of Pennyland, heiress of her cousin Grizel Budge (d. 1798) of Dale & Toftingall, Halkirk, Caithness. His sister Miss Euphame ("Aunt Effie") Threipland (1713- ) is said to have run the estate in his absence. Dr Threipland was President of the Royal Medical Society from 1766.