Prior to making his professional debut, Luke played Jersey Flegg Cup for Canterbury-Bankstown alongside fellow New Zealander and future Kiwis teammate Sonny Bill Williams. Luke made his NRL debut for the South Sydney Rabbitohs in round 12 of the 2007 NRL season against the Melbourne Storm at Olympic Park Stadium, coming off the bench. Luke had his first NRL start in round 19 Against the North Queensland Cowboys, playing at hooker. He scored his first NRL try and was awarded the Brut Man of the Match award for his efforts. Luke tasted finals football in his debut year, coming off the bench in the Rabbitohs 30 – 6 loss to the Manly-Warringah Sea Eagles. He was awarded the John Sattler Rookie of the Year at the South Sydney annual Red and Green Ball and presentation night held at the AJC function centre at Randwick Racecourse Sydney. He also was second only to Israel Folau in the Dally M Rookie of the Year award. His year was capped off by being named in the Train on Squad for the New Zealand national rugby league team.