Research by Cook and his colleagues has shown that past use of antidepressants can influence the brain's reaction to antidepressant placebos, that standard advice on diet and exercise for heart health can also lead to better brain health, that different types of advertisement evoke different types of brain activity, that electroencephalogram measurements could predict the outcome of antidepressant drug treatment on an individual patient long before the drugs make any observable changes to the patient's moods, and that electrical stimulation of the trigeminal nerve can be an effective alternative to drug therapy for depression.