After the 2010 season, Uribe reached an agreement on a three-year contract with the Los Angeles Dodgers. His first season with the Dodgers was one of his worst seasons as he made two trips to the disabled list and only managed to appear in 77 of 162 games, his fewest games since 2001. His production was the weakest of his career, as he hit a subpar .204 with four home runs and 28 RBIs. He was placed on the disabled list on July 30, with what was described as abdominal pain. He was expected to return after 15 days, but the injury didn't get better and was recharacterized as a sports hernia, which needed season-ending surgery.