"Defence" was sunk on 31 May 1916 during the Battle of Jutland, the largest naval battle of the war. Escorting the main body of the Grand Fleet, the ship was fired upon by one German battlecruiser and four dreadnoughts as she attempted to engage a disabled German light cruiser. She was struck by two salvoes from the German ships that detonated her rear magazine. The fire from that explosion spread to the ship's secondary magazines, which exploded in turn. The only known survivor was Govan man Richard Creath.