The show features the host on a green-screened set with a screen to their right. The show is broken up into various segments that focus on themes such as reality television shows or shows on E!. The host introduces each clip, which is then played, then comments on the clip before moving on to the next one. There is a live audience on the show, composed of a small group of E! employees, their family, and friends, along with the typical production personnel. The audience is involved in the show, laughing and cheering along with the clips. The 2020 revival includes a second camera position stage right, where the host can present other content on a second auxiliary video display.