The grandchild of the original Doctor Poison, this second incarnation appears in league with the demi-goddess Devastation. Doctor Poison's sex remains ambiguous, the only clues being long fingernails and a lipsticked grimace. She also joined the second Villainy Inc. and once again battled Wonder Woman. This incarnation of Doctor Poison confirmed that her grandmother did battle Queen Hippolyta as Wonder Woman during World War II. She also explains that her grandmother met her own demise by the creation of the drug called "Reverso". The original Doctor Poison accidentally reversed her own growth patterns and had forgotten the antidote by becoming too young too fast, eventually reverting to a fetus and then nothing.