That set the stage for Wilson's most successful big-league season, with the White Sox. He won a career-high 15 games (losing eight), and led the American League in shutouts, with five. However, he did not earn a place on the 1957 AL All-Star team. In , the 36-year-old Wilson concluded his 16-season playing career, working in 28 games for the White Sox, 23 in a starting role. In his final MLB game, September 14 against the Washington Senators, he worked 8 innings and surrendered five earned runs, but was credited with the victory in a 6–5 Chicago triumph. That season he also continued his skein of errorless games as a pitcher. On June 15, 1955, as an Oriole, he muffed an eighth-inning foul pop-up by the White Sox' Jim Rivera for an error. It was the last miscue he would commit in his career, which spanned 116 games through his 1958 retirement. Wilson posted a career .988 fielding percentage, committing only 4 miscues in 333 total chances.