In February 2016 "Edmonton" and "Saskatoon" sailed from Esquimalt to join Operation Caribbe. On 25 March, in conjunction with the United States Navy destroyer , "Edmonton" intercepted drug smugglers in international waters off the coast of Central America. After being stopped, the smuggling vessel attempted to dump its cargo overboard. "Edmonton", working with a LEDET detachment, recovered 27 bales of cocaine equalling . "Edmonton" and "Saskatoon" returned to Esquimalt on 29 April 2016. On 6 October, and "Edmonton" left Esquimalt to participate in Operation Caribbe along the Pacific coast. Between 15 and 18 November, "Edmonton" disrupted three separate shipments of illegal narcotics. On 15 November, "Edmonton" recovered from the ocean after a fishing vessel was intercepted by the United States Coast Guard. On 17 November, a second fishing vessel was stopped by the United States Coast Guard and "Edmonton" recovered 16 bales of cocaine weighing roughly from the ocean. On 18 November, "Edmonton" took 15 bales of cocaine weighing roughly from the ocean after the drug smugglers escaped. "Brandon" and "Edmonton" returned to Esquimalt on 16 December.