Several symptoms are related to the tested exposure to benzotrichloride (BTC) in rats: irritation of the eyes, the skin and the respiratory tract. Under occlusive conditions, rabbit skin which was exposed to BTC showed irritation. Next, severe eye irritation was reported in rabbits, after administering 0.1 mL of BTC. This eye irritation lasted up to 7 days. Finally, several rat studies into the acute toxic effects indicate that the respiratory system will be irritated after inhalation or oral uptake of BTC.