In 1935, US 17 was rerouted to overlap with US 701 between Charleston and Georgetown. Between Clinton and Newton Grove, US 701 was straighten, leaving behind various secondary roads in the area. By 1948, US 701 was placed on a new routing along Southeast and Northeast Boulevards, leaving behind US 701A. In 1950, US 701 was rerouted from Conway to Tabor City, leaving behind today's SC 410. In 1956, US 701 was placed on new bypass west of Whiteville, its old route eventually became US 701 Bus. In 1957, US 701 was placed on a new bypass east of Tabor City, leaving behind what became US 701 Bus; also same year a new bypass was constructed west of Clarkton, its old route also becoming US 701 Bus.