East of the Iowa River is the Meskwaki Settlement, which is home to about 800 Meskwaki Indians and the Meskwaki Casino and Resort. As it heads into the Tama–Toledo area, the expressway bisects the two communities. Between the two cities, it meets US 63 at a partial cloverleaf interchange. From US 63 it turns to the southeast to skirt Tama's east side. It rejoins the former alignment of the highway east of Tama and heads due east, along section lines in Tama and Benton Counties, and does not enter another town for .