On September 11, 2017, in the season opener against the Minnesota Vikings on "Monday Night Football", Ginn had one rush for five yards and four receptions for 53 yards in his Saints debut. Overall, in the 2017 season, he had 53 receptions for 787 receiving yards and four receiving touchdowns. The Saints made the playoffs and faced off against the Carolina Panthers in the Wild Card Round. In the 31–26 victory, he had four receptions for 115 yards and a touchdown. In the Divisional Round, he had eight receptions for 72 yards in the 29–24 loss to the Minnesota Vikings.