Jessica Drew's life settles down until Charlotte Witter, a villainess going by the Spider-Woman name, steals her powers and leaves her near death. Jessica is taken from the hospital to New York City by Madame Web who directs her and Mattie Franklin (yet another woman who has assumed the Spider-Woman name) to track down Witter. Under Madame Web's guidance, Franklin absorbs from Witter the powers of all four Spider-Women. Afterwards, Jessica remains with Madame Web for a time, helping her to watch over Mattie. Jessica's powers gradually return to her during this time, but are now unreliable, failing her unexpectedly on occasion.