Pennsylvania Route 374 (PA 374) is a state highway located in Susquehanna County, Pennsylvania. The western terminus is at PA 92 in the community of Glenwood in Lenox Township. The eastern terminus is at PA 171 / PA 371 in the community of Herrick Center near Union Dale in Herrick Township. The route is a two-lane undivided road that passes through rural areas of farms and woods in southern Susquehanna County. PA 374 intersects PA 407 and Interstate 81 (I-81) in Lenox Township and forms a concurrency with PA 106 in Clifford Township.