Efi Foundoulaki insists on the "activity of the triangle Picasso-Cézanne-El Greco, which is established in "Les Demoiselles d'Avignon"". Foundoulaki analyzes the "Opening of the Fifth Seal" and states that the clothed figure in the left part of the painting and the naked figures to the right showed the contradiction between profane and divine love. According to Rolf Laesse, this may have been the original inspiration of Picasso who in a preliminary drawing of the "Demoiselles" depicted a medical student holding a skull or a book and entering a room where there is a sailor among nude women. Richardson, however, conjectures that Picasso knew the interpretation by Cossio concerning the "Opening of the Fifth Seal" and based his theory extensively on this conjecture.