After C.A. López died in 1862, he left his son F.S. López as his successor as president. Eliza then became the "de facto" first lady, as she and López never actually married. Eliza Lynch would spend the next fifteen years as the most powerful woman in the country. While she never married López, her marriage to Quatrefages was annulled on the grounds that it did not fulfill the legal obligations for it to be considered a lawful marriage (he had not received permission to marry from his commanding officer, and they had no children together). This is supported by his remarriage in 1857, a marriage from which he had children.