The Athletics traded Fox to the Chicago White Sox for Joe Tipton on October 29, . He spent the next 14 seasons with the Sox, making 12 AL All-Star teams and 15 of 16 AL All-Star Game selections beginning in 1951 (two All-Star games were played in 1959 through 1962) when he batted .313. The White Sox finished in third place in each season between 1952 and 1956, followed by second-place finishes in 1957 and 1958 (Baseball-Reference.com lists Billy Pierce and Minnie Miñoso as the top White Sox players during most of those years, as reflected by wins above replacement (WAR), but Fox had the team's highest WAR in 1957).