At inter-county level, Comerford was part of the successful Kilkenny minor team that won the All-Ireland Championship in 1990 before later winning a Leinster Championship with the under-21 team in 1993. A two-year tenure with the London senior team yielded an All-Ireland B Championship in 1995. Comerford joined the Kilkenny senior team in 1996. From his debut, he was a regular at midfield, centre-forward or wing-forward and made a combined total of 53 League and Championship appearances in a career that ended with his last game in 2003. During that time Comerford was part of three All-Ireland Championship-winning teams – in 2000, as captain of the team in 2002 and as a substitute in 2003. He also secured six successive Leinster Championship medals and two National Hurling League medals.