His role in "Sayonara" was a dramatic departure from his previous work. In this film, co-starring with Marlon Brando, he played Joe Kelly, an American airman stationed in Kobe, Japan during the Korean War, who marries Katsumi, a Japanese woman (played by Miyoshi Umeki), but is barred from taking her back to the United States. His moving portrayal of Kelly's calm resolve not to abandon the relationship, and the touching reassurance of Katsumi, impressed audiences and critics alike. Buttons won the Academy Award for Best Supporting Actor and Umeki won the Academy Award for Best Supporting Actress for the film.