Another alternative is playing 4.Bxc6 immediately. The main replies for Black are 4...dxc6 and 4...bxc6, the latter of which is playable in the Berlin Defense, unlike the Exchange Variation in the Morphy Defense. This may transpose into the Anti-Berlin above if White continues with 5.d3, or in the case of 4...bxc6, to the main line with 5.0-0 Nxe4 or 5.d4 Nxe4, but White has other continuations to 4...bxc6, such as 5.Nc3, and Black has other replies to both 5.0-0 and 5.d4.