"Turner & Hooch" has been referred to in various films and television shows, including the NBC/ABC medical sitcom "Scrubs", in which main characters J.D. and Turk modify shift schedules so that Doctors Turner and Hooch are teamed up as a surgical team in the episode "My Faith in Humanity" (Doctor Turner was played by Jim Hanks, Tom Hanks' brother). They actually make a good team, and are disappointed when they have to disband. Another episode has Turk offended at JD's assumption that Turner and Hooch was an interracial buddy movie, an assumption made based on the aforementioned Hooch. In the second season of "Castle", Beckett and Castle compare themselves to Turner and Hooch, with Castle being Hooch. This comparison returned in the Castle season 7 episode "Kill Switch".