After three minor league seasons with various teams in the ECHL and AHL, Konopka made his NHL debut in 2005–2006, playing 23 games for the Mighty Ducks of Anaheim. After the Ducks were eliminated, he returned to Portland in the AHL, where he led all playoff scorers in power play goals and assists. In 2006–07, he returned to the minors, playing for Portland in the AHL. On January 26, 2007, he was traded by the Anaheim Ducks along with Curtis Glencross and a draft pick to the Blue Jackets in exchange for forwards Mark Hartigan, Joe Motzko and a draft pick. He played for Columbus's farm team in the AHL, the Syracuse Crunch, with occasional call-ups to the Blue Jackets.