From her re-election in 1933 until her retirement in 1960, she faced opposition only once. During the 1949 Northern Ireland General Election, with anti-partition agitation a common theme across the region, she was opposed in South Londonderry by a Nationalist Party candidate, T.B. Agnew, whom she defeated. She was a Parliamentary Secretary to the Ministry of Education from 1 December 1937 to 15 March 1944. She was also Chair of the Northern Ireland General Health Services Board from 1948 to 1949. She served as Minister of Health and Local Government from 26 August 1949 to 13 March 1957 and became a member of the Privy Council of Northern Ireland in 1949. She was elevated to Dame Commander of the Order of the British Empire in the 1949 Birthday honours "for public services", having previously been appointed as an OBE, and was advanced to be a Dame Grand Cross of the Order of the British Empire (GBE) in 1957.