The second quatrain applies the principles of the first: "being full of your ne'er-cloying sweetness, / To bitter sauces did I frame my feeding;" "ne'er" firstly means never, as in the poet is never sated by the youth's sweetness. But "nere" meaning 'near' or 'almost' can't be ignored: the poet's palate is "full" of the friend's sweetness, that is nearly rich enough to cause gagging ("cloying"). To refresh his palate the poet has designed his diet to include "bitter sauces". Bitter digestifs typically contain carminative herbs, which are thought to aid digestion. As a consequence, the poet has found himself inoculated against future ailments. He has been made "sick of welfare" but finds it appropriate ("a kind of meetness", with echoes of 'meat') that he has become ill ("To be diseased"), before there was any cause to be so ("ere that there was true needing").