Years after the G.I. Joe Team has disbanded, Kamakura finds evidence that Cobra Commander has returned to the United States. Snake Eyes forwards this information to Duke, who uses it to have the G.I. Joe Team reinstated. Cobra Commander calls together the members of his organization, to let them know about his plan to take over the United States with nano-mites. Destro is the last to arrive, but after hearing the Commander's plan, he turns the tables on Cobra Commander, and takes control of Cobra.