In fiction, Druitt is depicted as the murderer in the musical "Jack the Ripper" by Ron Pember and Denis de Marne. In John Gardner's Sherlock Holmes story "The Return of Moriarty", Professor Moriarty's criminal exploits are hampered by increased police activity as a result of the Jack the Ripper murders. He discovers that Druitt is the murderer and so fakes his suicide in the hope that the police will lose interest once the murders cease. In Alan Moore's graphic novel "From Hell", Druitt is portrayed as a patsy for the royal family, made to look guilty of the Ripper murders in order to protect the real killer, Sir William Gull.