At the French Open, Bondarenko fell to 20th seed Dominika Cibulková in the first round in three sets. She then performed badly at grass unable to duplicate her performance in the past two years, losing in the second round of the Ordina Open and first round of Wimbledon to Elena Baltacha. She then made it to her first semifinal since the 2007 İstanbul Cup, which was more than two years ago. She then lost to sister Kateryna 1–6, 3–6 in the first round of the ECM Prague Open breaking the tie between the two as she trails her sister 3–4 in head-to-head now. She then reached the third rounds of LA Women's Tennis Championships, losing to Sharapova in three, and Rogers Cup, losing to Serena Williams. She then reached the second rounds of Western & Southern Financial Group Women's Open and Pilot Pen Tennis. In the first round of the US Open she beat Alla Kudryavtseva 3–6, 6–3, 6–2, but lost to Gisela Dulko in the second round. In her first tournament since the US Open, she lost in the first round of the Toray Pan Pacific Open to Vera Dushevina 6–1, 5–7, 1–6. She lost in the third round of the China Open to Svetlana Kuznetsova 3–6, 6–4, 0–6 after defeating Ágnes Szávay and Sara Errani both in straight sets. She played her last tournament of the year at the Kremlin Cup, where she beat Anna Chakvetadze, Nadia Petrova and Tsvetana Pironkova all in straight sets before losing to eventual champion Francesca Schiavone in the semifinals in straight sets as well.