NY 434 remains a four-lane divided highway for its first in the city, following the Susquehanna River along the north edge of a vast neighborhood that comprises the south half of Binghamton. It soon approaches the vicinity of downtown Binghamton, where the route connects to Pennsylvania Avenue by way of an interchange located across the river from the city's center. Another grade-separated junction with Conklin Avenue follows, at which point NY 434 turns northward and crosses the river into downtown as State Street. On the north bank of the river, NY 434 meets NY 363, a freeway linking downtown to the Southern Tier Expressway north of the city. NY 434 continues on, narrowing to two divided then undivided lanes for its final two blocks as it passes the Broome County Veterans Memorial Arena and ends at a junction with US 11 (Court Street).