Michael Servetus, using the name "Michel de Villeneuve", who already had his first death sentence from the University of Paris, anonymously published a Dioscorides-De Materia Medica in 1543, printed by Jean & Francois Frellon in Lyon. It has 277 marginalia and 20 commentaries on a De Materia Medica of Jean Ruel. According to Gonzalez Echeverría, to be associated to an anonymous Pharmacopeia that "Michel de Villeneuve" published the same year, meant to be a single unit, which is typical when it comes to De Materia Medica-Pharmacopeia. This work had six later editions, in 1546 and 1547 by Jean Frellon, who considered Michael de Villeneuve "his friend and brother", another in 1547 by Thibaut Payen, etc.