From 1825 until his death in 1852 Chinnery based himself in Macau, but until 1832 he made regular visits to Canton (now Guangzhou). He painted portraits of Chinese and Western merchants, visiting sea-captains, and their families resident in Macau. His work in oil paint was closely imitated by the Cantonese artist Lam Qua, who himself became a renowned portrait painter. Chinnery also painted landscapes (both in oils and in watercolours), and made numerous drawings of the people of Macau engaged in their daily activities.