In 1861 the London and North Western Railway revived powers granted to the Lancashire and Yorkshire Railway to build a railway from Eccles to Wigan through the town. Tyldesley railway station was to the east of the junction of the branch to Kenyon Junction on the Liverpool to Manchester Line via Leigh and Pennington. The Earl of Ellesmere cut the first sod at Worsley on 11 September 1861 and the line opened to traffic on 1 September 1864. The Tyldesley Loopline closed on 3 May 1969 as a result of the Beeching Axe.