On February 5, 2017, Branch was part of the Patriots team that won Super Bowl LI. In the game, the Patriots defeated the Atlanta Falcons by a score of 34–28 in overtime. The Patriots trailed 28–3 in the third quarter, but rallied all the way back to win the game, which featured the first overtime game in Super Bowl history and the largest comeback in the Super Bowl. Branch recorded three tackles, 0.5 sacks, and a crucial fumble recovery in the game.