Uzo's "Walls & Bridges" is the story of a white nun Ellen Landress Bowkett who leaves her Order to marry a black painter Mark D. Kennerly who is blinded in a random act of violence. While developing the script, Uzo spent two years painting the large size Miro-esque murals featured in the film. The film premiered October 14, 1992, at the John F. Kennedy Center for the Performing Arts Washington, DC. It was one of two films representing the United States at the Sixth Festival of the Americas, sponsored by the Organization of American States and the American Film Institute. He is considered the first African-born person to direct an American feature film.