After the fall of Cabinet Marijnen Cals was asked to lead a new cabinet. Following a successful cabinet formation Cals formed the Cabinet Cals and became Prime Minister of the Netherlands taking office on 14 April 1965. The cabinet fell just one year into its term after a major political crisis and following a difficult cabinet formation wasn't included in a new cabinet. Cals left office following the installation of the caretaker Cabinet Zijlstra on 22 November 1966 and announced his retirement.