"Canons" refers to the canons or monks of the Augustinian priory of St Bartholomew in Smithfield, London. In mediaeval times the site was a part of the endowment of the Priory of St Bartholomew's which operated St Bartholomew's Hospital in London. Following the dissolution of the monasteries the land was sold in 1543 into private hands. A large house was built there during the 16th and 17th centuries at one time owned by Thomas Lake, James I's Chancellor of the Exchequer.