"H {N)Y P N(Y} OSIS", Parreno's first major U.S. exhibition, ran from June until August 2015 within the monumental interior of Park Avenue Armory’s Wade Thompson Drill Hall, New York and transformed the traditional exhibition experience through an interplay of film, sculpture, and the spectral presence of sound and light. Shortly after, in October 2015 until February 2016, Parreno presented "Hypothesis", at HangarBicocca in Milan, his first survey exhibition in Italy. The show, curated by Andrea Lissoni, was inhabited by a series of key pieces together with recent works and music according to a mise en scène devised by Parreno.