To understand "tactile sensory substitution" it is essential to understand some basic physiology of the tactile receptors of the skin. There are five basic types of tactile receptors: Pacinian corpuscle, Meissner's corpuscle, Ruffini endings, Merkel nerve endings, and free nerve endings. These receptors are mainly characterized by which type of stimuli best activates them, and by their rate of adaptation to sustained stimuli. Because of the rapid adaptation of some of these receptors to sustained stimuli, those receptors require rapidly changing tactile stimulation systems in order to be optimally activated. Among all these mechanoreceptors Pacinian corpuscle offers the highest sensitivity to high frequency vibration starting from few 10s of Hz to a few kHz with the help of its specialized mechanotransduction mechanism.