Sechele had a profound knowledge of the Bible and a commitment to spreading Christianity. He began with his own people, teaching them to read and introducing them to the Bible. He also travelled many hundreds of miles to evangelise other African peoples. When Moffat led a group of missionaries into Matabeleland in 1859, he discovered that Sechele had preceded him and that the local Ndebele people held Christian prayers. Moffat's mission had little success as an outbreak of lung disease among the missionaries' oxen resulted in fear of the white missionaries. Officially, there were no converts among the Ndebele until the 1880s.