In Week 2, in the 48–23 victory over Chicago Bears, Fitzgerald had 112 receiving yards and caught three touchdown passes, the first time he accomplished the feat during the regular season in his career. For his performance, he was named NFC Offensive Player of the Week for the fourth time in his career. In the next game, he had nine receptions for 134 yards and two touchdowns against the San Francisco 49ers. On November 15, he had ten receptions for 130 yards against the Seattle Seahawks. In Week 13, he became the youngest player to reach 1,000 career receptions; Dallas Cowboys tight end Jason Witten joined him the same day as the 11th and 12th players to reach this milestone. He closed out the 2015 regular season with a receiving touchdown in the last two games against the Green Bay Packers and Seattle Seahawks. The Cardinals finished with a 13–3 record and won the NFC West.