On 11 May 2010, Lloris was named in Domenech's 30-man preliminary squad to participate in the 2010 World Cup, later being named to the final 23-man team and installed as first-choice goalkeeper. On 11 June 2010, Lloris made his World Cup finals debut in the team's opening group stage match against Uruguay, earning a clean sheet in a 0–0 draw. Lloris appeared in both of France's other group stage matches, against Mexico and hosts South Africa. Against South Africa, Lloris committed a goalkeeping error which resulted in the opening goal for the hosts. He redeemed himself later in the match, however, by producing several saves to limit the South Africans' chances of progressing to the knockout rounds. France lost the match 2–1, which resulted in the hosts' elimination from the competition.