As She-Hulk, Jennifer possessed powers similar to those of her cousin, though at a reduced level. She also possessed a less monstrous, more Amazonian appearance. Initially, the transformation to her She-Hulk form was triggered (as with Bruce Banner's) by anger. Like her cousin Bruce, his counterpart, the Leader, Doc Samson and most other persons mutated by exposure to gamma radiation over the years, her mutated form was originally explained as being molded by her subconscious desire to look like the ideal woman. She eventually gains control of her transformations when Michael Morbius cures her of a lethal blood disease. As a criminal defense lawyer, she defended Morbius in his trial for his vampiric killings.