On September 5, 1922, she died in her sleep of heart failure. A service was held in Palo Alto, California, and her remains lay at Alta Mesa Cemetery until they were transferred, along with those of her sister, to New Haven, Connecticut. She was buried next to her husband and their infant child in Evergreen Cemetery, New Haven, Connecticut. She left a will written in thirteen sections, which she signed thirteen times. The belongings in Winchester Mystery House were left to her niece, Marian I. Marriott, who took what she wanted and auctioned the rest off.