Thomas Jefferson and Isabella Perkerson had seven children. One of their daughters, Matilda "Till," married Jeremiah Silas Gilbert (1839-1932), a son of the first practicing physician ever to live in what is now Fulton County, and lived in the Gilbert House which is now a City of Atlanta Landmark Site, at 2238 Perkerson Road. Another daughter, Elizabeth "Lizzie," married Sumner E. Butler from New York and returned to live in the Perkerson home in her later years. It has been noted that at the time of the Civil War, the Perkersons owned 405 acres, had 3 dogs, 4 children ages 6 to 18, and owned 8 slaves valued at $16,000, and household and kitchen items valued at $500.