The Church of "Saint Cyriacus in the Baths of Diocletian" (), was dedicated to this martyr, a former "titulus" church. The "tituli" were commonly named after their patron, often a lay patron in the early centuries: ""Cyriac"" in Greek signifies simply ""patron."" This ""titulus,"" to which a cardinal was assigned, whatever its claimed second- or third-century origins, existed certainly in the fifth century, when Marcianus was cardinal priest of the title of S. Ciriaco alle Terme di Diocleziano in 494, at the time of Pope Gelasius I. The titulus was suppressed in 1477 by Pope Sixtus IV in favor of Saints Ciro and Giulitta. In 1493, Pope Alexander VI restored the name of S. Ciriaco. The title was definitively suppressed in 1587 by Pope Sixtus V, who assigned a titulus of Sts Quirico e Giulitta to Cardinal Ferdinando de' Medici.