Sachen, the first of the five supreme masters, inherited a wealth of tantric doctrines from numerous Tibetan translators or "lotsawas" who had visited India: most importantly Drokmi Lotsawa, Bari Lotsawa and Mal Lotsawa. From Drokmi comes the supreme teaching of Sakya, the system of Lamdre "Path and its Fruit" deriving from the mahasiddha Virūpa based upon the Hevajra Tantra. Mal Lotsawa introduced to Sakya the esoteric Vajrayogini lineage known as "Naro Khachoma." From Bari Lotsawa came innumerable tantric practices, foremost of which was the cycle of practices known as the "One Hundred Sadhanas". Other key transmissions that form part of the Sakya spiritual curriculum include the cycles of Vajrakilaya, Mahākāla and Guhyasamāja tantras.