The Genoese, being interested in profit rather than conquest, controlled the trade-posts and warehouses, in particular the trade of mastic, alum, salt and pitch. Other trades such as grain, wine oil and cloth and most professions were run jointly with the locals. After a failed uprising in 1347, and being heavily outnumbered (less than 10% of the population in 1395), the Latins maintained light control over the local population, remaining largely in the town and allowing full religious freedom. In this way the island remained under Genoese control for two centuries. By 1566, when Genoa lost Chios to the Ottoman Empire, there were 12.000 Greeks and 2.500 Genoese (or 17% of the total population) in the island.