Canto II. In the second part of the poem the Indian chiefs, Sepé and Cacambo, try to negotiate with the Portuguese general on the margin of the Uruguai River. The agreement is impossible once the Portuguese Jesuits denied to accept the Spanish domain over their lands. After this the Indians, led by Sepé, bravely fight the Portuguese army but they are subjugated by the Portuguese's fire weapons. Sepé dies in this battle and Cacambo leads the withdrawal of the guarani army.