Ebtekar served as spokeswoman for the students in the Iran hostage crisis of 1979, where Muslim Student Followers of the Imam's Line occupied the US Embassy and held 52 Americans hostage for 444 days. Selected because of her good command of English, she made regular appearances on American television as translator and spokeswoman for the students, where she presented the official positions of the students. She was referred to as "Mary" by foreign press, and "Tiger Lily" by the hostages, a play on the translation of "Niloufar".