After passing St. Joseph's Hospital, NY 24 crosses through Plainedge and into a large cloverleaf interchange (exit 7) with the Seaford–Oyster Bay Expressway (NY 135). Three blocks to the east, NY 24 condenses to four lanes, entering a partial cloverleaf interchange with the Bethpage State Parkway (exit B3). After crossing over the Bethpage, the route proceeds northeast through the town of Oyster Bay, crossing into the town of Farmingdale. After crossing under a line of the Long Island Rail Road, the route crosses Merritt Avenue at-grade, entering a junction with NY 109 (Fulton Street). Past the junction with NY 109, NY 24 changes monikers to Conklin Street, crossing through Farmingdale as a four lane street.