West of Mitchell Road, NY 96 takes a more southerly alignment than the canal as it enters the densely populated village of Pittsford and meets the northern and eastern termini of NY 64 and NY 252, respectively, at the intersection of Jefferson Road and South Main Street. NY 64 heads to the south along South Main Street and NY 252 continues along Jefferson Road to the west while NY 96 turns north, proceeding into the heart of the village along South Main Street. In the village center, NY 96 intersects Monroe Avenue and State Street, which carry NY 31 east–west through Pittsford. The route continues on, becoming North Main Street as it crosses the Erie Canal and passes under the CSX Transportation-owned West Shore Subdivision. Just north of the railroad overpass is a junction with the southern terminus of NY 153, the most direct route between Pittsford and nearby East Rochester.