Rene II de la Jaille married Magdelaine de Montgomery, the sister of Gabriel, Comte de Montgomery in 1530. They had a single daughter - Françoise de la Jaille. She married Gabriel d'Apchon - linking two of the great feudal families. He took part in the Italian campaign in 1539 and was made a Knight of the King's Order, a rare and distinguished honour. By the 1550s, Rene II was a Knight of the Order of St Michael, Senechal of Anjou, and a Gentleman of the court of Catherine de' Medici. In 1555, he was captain general of the rear-guard of the French forces. This had originally been an elite troupe, but was now little more than an undisciplined rabble of conscripts. In the campaign in Picardy against the Spanish, Rene was captured and ransomed for 20,000 ECU. This was a considerable sum and virtually ruined the family. He sold the estates in Anjou and most of those in the Loudun area: Ranton was one of the few estates he kept. He died two years later, still fighting - this time at the battle of St Quentin in 1557.