Seeded seventh at the US Open, Kubot and Melo defeated Divij Sharan and Artem Sitak in the second round. In the third round they overpowered the 2018 French Open champions Nicolas Mahut and Pierre-Hugues Herbert. They continued their great form with a straight set win over Austin Krajicek and Tennys Sandgren to reach their first US Open semifinal. In the semifinal they defeated Malek Jaziri and Radu Albot for a spot in the final of the Men's doubles event at the 2018 US Open. Kubot and Melo came into the tournament having lost five of their previous seven matches and also ended up losing to the third-seeded Americans Mike Bryan and Jack Sock in the final.