Biss has begun examining, both in concert and academically, the concept of a composer's "late style," focusing on musicians who went in surprising directions towards the end of their lives. He has put together several programs of Bach, Beethoven, Brahms, Britten, Elgar, Gesualdo, Kurtág, Mozart, Schubert, and Schumann's later works, which he performed with the Brentano Quartet and Mark Padmore in the UK, Italy, the Netherlands, and across the United States. He also gave masterclasses at Carnegie Hall in connection with the idea of late style and published "Coda," a Kindle single on the topic in March 2017.