The LV= Cup featured a Harlequins team stripped of its players on international duty. Relying on a team of developing players, the club remained unbeaten throughout the pool stage. Harlequins beat Bath Rugby (31–23) in the semi-final at The Stoop, and defeated and Sale Sharks (32–14) in the final at Sixways Stadium. This was Harlequins' third title in the English/Anglo-Welsh Cup and the first since the inception of the Anglo-Welsh format. This title granted Harlequins a place in the 2013-14 Heineken Cup.