Mississippi State struggled to a 3–9 record in 2006. State lost its first three games of the season to South Carolina, No. 4 Auburn, Tulane, State beat UAB to get its first win of the year in the fourth game. Losses to No 9 LSU and No. 4 West Virginia followed, then State defeated Jacksonville State to snap the two-game skid. State then lost to Georgia and Kentucky. MSST then upset Alabama in Alabama before losing to No. 5 Arkansas and Ole Miss.