Cuse is showrunner, executive producer, developer, and writer of "Locke & Key", an adaptation of Joe Hill's comic-book series. Cuse's Genre Arts production company, and IDW Entertainment produce the series. The series was created by Hill and developed by Cuse, Aron Eli Coleite, and Meredith Averill. "Locke & Key" is a horror/fantasy series that revolves around three siblings, who after the gruesome murder of their father, move to their ancestral home in Massachusetts, only to find the house has magical keys that give them a vast array of powers and abilities. Little do they know, a devious demon also wants the keys, and will stop at nothing to attain them.