The community was named for early settler Sam Worthington, who arrived prior to the first Seminole War of 1814–1819. The mineral spring on the Santa Fe River was alleged to have medicinal benefits, attracting people from the late 1800s to the early 1900s. In the early years, swimming was segregated, with men and women assigned specific time intervals. In 1906, the new owner constructed a 12'×12' concrete box around the spring to divert water into a 90'×50' concrete pool with a wall dividing the bathing area into sections for men and women. The complex included a hotel, recreation hall and bathhouse for the spring pool.