Bertrand II had eight children: René, Gilles, Madelon, Pierre, Jeanne, Marguerite, Isabelle and Françoise. As was usual in those days, the eldest son, Rene, inherited the titles to all the major estates. At this time these were La Roche-Morier, La Grande Jaille, de Beuxes, Ranton, La Jaille-en-Chahaigne, La Varenne, La Roche-Talbot and Souvigne. Rene married Jeanne Herisson in 1494. Rene de la Jaille was several times in court, accused of various misdemeanors, and died in 1515. He died a month after the battle of Marignan, and it is likely that he died of wounds.