From its inception until October 31, 2018, WTMJ-TV was a sister station to WTMJ radio (620 AM) and WKTI (94.5 FM). The radio stations are now owned by Good Karma Brands, but continue to share studios and some operations (including a long-term weather forecasting agreement and engineering staff) with Scripps and WTMJ-TV; Good Karma's WAUK (540 AM) moved to Radio City in 2019 to consolidate their local operations. In January 2021, it became a sister station to WPXE-TV, after Ion and its stations were purchased by Scripps; WPXE-TV currently operates out of separate studios in Glendale, Wisconsin, though it had been operated from the WTMJ-TV studios under a joint sales agreement (JSA) from 2000 to 2005.