Kanner indicated that the fundamental issue of this disorder is the children's inability to relate to people and objects in an ordinary way from birth. Distinguishing between the symptoms of the two disorders, Kanner explained that a person with schizophrenia steps outside his or her world and departs from already existing relationships, whereas the children he described had never established such relationships, experiencing an extreme aloneness from very early on. The notion of the innate nature of what Kanner called "extreme aloneness" was evident by recurrent reports of the failure of the children to "assume at any time an anticipatory posture" and adjust their bodies upon being picked up by their parents. The preferences the children had towards solitude manifested in complete disregard and ignorance of any external outputs that may interfere with them, such as direct physical contact, sound, or motion. Regarding the children's lack of interest towards people, Kanner stated that 'it would be best to get these interferences over with, the sooner to be able to return to the still much desired aloneness".