Virginia Clay-Clopton (1825–1915) was a political hostess and activist in Alabama and Washington, D.C. She was also known as Virginia Tunstall, Virginia Clay, and Mrs. Clement Claiborne Clay. She took on different responsibilities after the Civil War. As the wife of US Senator Clement Claiborne Clay from Alabama, she was part of a group of young southerners who boarded together in the capital in particular hotels. In the immediate postwar period, she worked to gain her husband's freedom from imprisonment at Fort Monroe, where Jefferson Davis, former president of the Confederacy, was also held.