As in most rural areas throughout Missouri, voters in Pemiscot County generally adhere to socially and culturally conservative principles, but are more moderate or populist on economic issues, typical of the Dixiecrat philosophy. In 2004, Missourians voted on a constitutional amendment to define marriage as the union between a man and a woman—it passed Pemiscot County with 84.73 percent of the vote. The initiative passed the state with 71 percent of support from voters, as Missouri became the first state to ban same-sex marriage. In 2006, Missourians voted on a constitutional amendment to fund and legalize embryonic stem cell research in the state—it failed in Pemiscot County, with 52.41 percent voting against the measure. The initiative narrowly passed the state with 51 percent of support from voters, as Missouri became one of the first states in the nation to approve embryonic stem cell research. Despite Pemiscot County's longstanding tradition of supporting socially conservative platforms, voters in the county have a penchant for advancing populist causes, such as increasing the minimum wage. In 2006, Missourians voted on a proposition (Proposition B) to increase the minimum wage in the state to $6.50 an hour—it passed Pemiscot County with 78.01 percent of the vote. The proposition strongly passed every single county in Missouri with 78.99 percent voting in favor as the minimum wage was increased to $6.50 an hour in the state. During the same election, voters in five other states strongly approved increases in the minimum wage.