His "De institutione feminae christianae", published in 1523, was commissioned by Catherine of Aragon, Catholic Queen consort of Henry VIII of England, for her daughter, Mary to instruct her on the proper roles for her sex. It forbids the very role Queen regnant Elizabeth I would later fulfill with the support of England and its navy in defeating the Armada of Catholic Spain, originating from the country of the Catholic Monarchs, Catherine of Aragon's parents and leaders of the Spanish Inquisition that executed Vives' relatives: