Starting in Rudow, at the junction of Gross-Ziethener Chaussee and Neuköllner Straße, the U7 runs northwest below the road Alt-Rudow, before bearing west in the Gropiusstadt area. Because the settlement and underground construction there were planned simultaneously, the U7 follows no roads until it reaches Britz-Süd station, where it runs under Fritz-Reuter-Allee as far as Blaschkoallee station before joining the route of Buschkrugallee. It continues north, crossing the urban motorway and the Ringbahn while under Karl-Marx-Straße, then heads north-west under Hasenheide, Südstern, and Gneisenaustraße until it reaches Mehringdamm after a very sharp right curve. A tight left curve brings the U7 under the () to Möckernbrücke station, with another taking it back and below the area of the former (). The route continues west under Yorckstraße, Willmanndamm, Grunewaldstraße, Bayerischer Platz, and Berliner Straße, then heads north under Brandenburgische Straße to Adenauerplatz station.