The Greek Orthodox Church of Antioch adheres to the Eastern Orthodox Church, which is actually a group of autocephalous churches using the Byzantine rite and are the second largest Christian denomination within Christianity in Lebanon. Historically, these churches grew out of the four Eastern Patriarchates (Jerusalem, Antioch, Alexandria, and Constantinople) of the original five major episcopal sees (the Pentarchy) of the Roman Empire which included Rome. The final split took place in 1054. From that time, the Eastern Churches have continued to reject the claims of the Patriarchate of Rome (the Catholic Church) to universal supremacy and have rejected the concept of papal infallibility. Doctrinally, the main point at issue between the Eastern and Western Churches is that of the procession of the Holy Spirit and there are also divergences in ritual and discipline.