Jane Burden was born in Oxford, the daughter of a stableman, Robert Burden, and his wife Ann Maizey, who was a laundress. At the time of her birth, her parents were living at St Helen's Passage, in the parish of St Peter-in-the-East, off Holywell Street in Oxford which has since been marked with a blue plaque. Her mother Ann was and probably came to Oxford as a domestic servant. Little is known of Jane Burden's childhood, but it was certainly poor.