Reckless hunting and loss of habitat as a result of human settlement have led to a significant decline in the numbers of the bohor reedbuck, although this antelope tends to survive longer in such over-exploited areas as compared to its relatives. Natural calamities, like drought, are also major threats. While populations have declined in northern Cameroon due to degradation of floodplains through the construction of upstream dams, their habitat has been destroyed in Chad and Tanzania due to expansion of agriculture and settlement. Several deaths occur due to roadkill and drowning as well. During the dry season, bohor reedbuck are hunted with dogs and nets in Uganda. Reedbuck with the largest horns are prized by hunters.