In Bengal, the most prominent Baro-Bhuyan confederacy was led by Isa Khan of Sonargaon in the 16th century, which emerged during the disintegration of the Bengal Sultanate in the region, as a resistance to the Mughal expansion. They carved the land of Bhati and other areas of Bengal into twelve administrative units or "Dwadas Bangla". The Baro-Bhuyans gradually succumbed to the Mughal dominance and eventually lost control during the reign of emperor Jahangir, under the leadership of Islam Khan I, the governor of Bengal Subah.