Multiple RNA polymerases can be active at once, meaning many strands of mRNA can be produced very quickly. RNA polymerase moves down the DNA rapidly at approximately 40 bases per second. Due to the quick nature of this process, DNA is continually unwound ahead of RNA polymerase and then rewound once RNA polymerase moves along further. The polymerase has a proofreading mechanism that limits mistakes to about 1 in 10,000 nucleotides transcribed. RNA polymerase has lower fidelity (accuracy) and speed than DNA polymerase. DNA polymerase has a very different proofreading mechanism that includes exonuclease activity, which contributes to the higher fidelity. The consequence of an error during RNA synthesis is usually harmless, where as an error in DNA synthesis could be detrimental.