Ambrose made history by finishing third in the O'Reilly Auto Parts 250 at Kansas Speedway on 2 July 2006. This was the first time a non-American driver has finished in the top five of a truck series event since Canadian Ron Fellows won on the Watkins Glen road course on 26 June 1999. He also took the lead in the opening laps, becoming the first Australian to lead laps in Camping World Truck Series competition. The next week, he made further history by scoring his first pole position for the Built Ford Tough 225 at Kentucky Speedway, and then leading the most laps in the race itself, though he finished 19th. Ambrose finished 3rd in the Toyota Tundra 200 at Nashville Superspeedway after qualifying 11th.