He contested the Wantage constituency in June 1987, when 34. From 1995–9, Ladyman was a Thanet councillor and was appointed as Chairman of Finance of Thanet District Council. He was elected to Parliament in the 1997 United Kingdom general election, defeating Jonathan Aitken. He was a junior minister at the Department for Health from June 2003 until May 2005, when he was appointed Minister of State for Transport having narrowly held his seat in the 2005 General Election with a majority of 664 votes.