1863 was to alter the course of Alma-Tadema's personal and professional life: on 3 January his invalid mother died, and on 24 September he was married, in Antwerp City Hall, to Marie-Pauline Gressin-Dumoulin de Boisgirard, the daughter of Eugène Gressin-Dumoulin, a French journalist living near Brussels. Nothing is known of their meeting and little of Pauline herself, as Alma-Tadema never spoke about her after her death in 1869. Her image appears in a number of oils, though he painted her portrait only three times, the most notable appearing in "My studio" (1867). The couple had three children. Their eldest and only son lived only a few months dying of smallpox. Their two daughters, Laurence (1864–1940) and Anna (1867–1943), both had artistic leanings: the former in literature, the latter in art. Neither would marry.