Theano's husband opened up a school in Croton in Italy which primarily involved mathematics, philosophy, and nature. It is thought that Pythagoras accepted women and men in his school and at one point achieved 300 students in school while only 28 students were women. As multiple sources indicate, Pythagoras wanted to compete with other schools so he made his school not based on discrimination of genders, which influenced other women to pursue science and astronomy instead of being discriminated. It was also spoken that many men were inspired by the women studying in school. As Pythagoras life ending Theano took over as the head of the school with the help of her children. With Theano's life ending, the school still existed, even after 200 years after the deaths of both Theano and Pythagoras. Theano passed away during the 5th century B.C. and was thought to be buried right by their school.