Cuse and writer Graham Roland created a TV series based on Jack Ryan, the CIA analyst character, created by novelist Tom Clancy in the 1980s. The show was an original story that borrowed from rather than was an adaptation of any of Clancy's work. The series stars John Krasinski as Ryan, "an up-and-coming CIA analyst as he uncovers a pattern in terrorist communication that launches him into the center of a dangerous gambit with a new breed of terrorism that threatens destruction on a global scale." Amazon Video gave the series an eight-episode, straight-to-series order. Cuse co-wrote, with Roland, five of the eight episodes. and directed one, while also serving as the series showrunner. Amazon acknowledged "Jack Ryan" was one of the two most-binged Prime Original series worldwide to date.