Transportation in the Shenandoah Valley consists mainly of road and rail and contains several metropolitan area transit authorities. The main north-south road transportation is Interstate 81, which parallels the old Valley Turnpike (U.S. Route 11) and the ancient Great Path of the Native Americans through its course in the valley. In the lower (northern) valley, on the eastern side, U.S. Route 340 also runs north-south, starting from Waynesboro in the south, running through the Page Valley to Front Royal, and on to Harpers Ferry, West Virginia, where it exits the valley into Maryland. Major east-west roads cross the valley as well, providing access to the Piedmont and the Allegheny Mountains. Starting from the north, these routes include U.S. Route 50, U.S. Route 522, Interstate 66, U.S. Route 33, U.S. Route 250, Interstate 64, and U.S. Route 60.