KFBI was founded in 2006 by Sainte Partners II, L.P. owner Chester Smith to bring one of his stations to the Medford market. The station hit the air on July 3, 2006, about one month before the official launch of MyNetworkTV; the station launched with the network's imaging to save the costs of a two-month interim brand. The operations were out of the Sainte offices in Chico, California, home of KCVU, MyTV Northern California and three Spanish stations. The sales offices were located on North Riverside Avenue in Medford and Peter Rogers, former general manager at KMVU, served as the station's first full-time general manager.