After his time in art school, Soyer did not immediately begin working as a professional artist, and instead painted during his free time while working other jobs. Soyer's first solo exhibition took place in 1929. Beginning in the early 1930s, he showed regularly in the large annual and biennial American exhibitions of the Whitney Museum of American Art, the Carnegie Institute, the Art Institute of Chicago, the Corcoran Gallery of Art, the National Academy of Design, and the Pennsylvania Academy of the Fine Arts.