Huskey was expected to have a breakout season in 2000 with Minnesota as the Twins' everyday designated hitter, but he struggled offensively, hitting only five home runs in 215 at-bats. On July 15, 2000 he was traded with Todd Walker to the Colorado Rockies in exchange for Todd Sears and cash. The Rockies were in a pennant race and looking for power off of their bench. Huskey did not disappoint, hitting four home runs in only 92 at-bats while playing mostly left field.