Spann was waived by the team on September 2, 2006, and signed to the Patriots' practice squad the following day. He was signed to the Patriots' 53-man roster on September 30 before being waived from it on November 7. He was re-signed to the Patriots' practice squad on November 8, and again elevated to the 53-man roster on November 18. He was waived by the Patriots on November 22 and re-signed to their practice squad again on November 24. He was signed to the team's 53-man roster for a third time on December 9, where he spent the remainder of the season.