In 2006, Wiig made her film debut in the Christmas movie "Unaccompanied Minors", and in 2007, she appeared in Judd Apatow's comedy "Knocked Up", as a passive-aggressive assistant, and performed in Jake Kasdan's "", another Apatow-produced film. Between 2008 and 2010, she had supporting roles in numerous studio comedies, which opened to varying degrees of success, but gave her an initial exposure with audiences. In 2008, she made a cameo appearance as Bear Trainer Girl in the comedy "Semi-Pro", reuniting with "SNL" alum Will Ferrell, and played a yoga instructor in "Forgetting Sarah Marshall", alongside Jason Segel and Mila Kunis, and also a self-involved surgeon in David Koepp's "Ghost Town", with Ricky Gervais.