In 1922, the New England states adopted a region-wide road marking system. Primary routes were to be assigned route numbers between 1 and 99 and marked as black numerals on yellow bands painted on poles along the route. The route running from Wareham, Massachusetts and Ossipee, New Hampshire via Boston and Manchester, New Hampshire was designated as New England Route 28. Route 28 utilized the main road between Wareham and Middleborough (Wareham Street), from which it then traveled along Everett Street and Summer Street until the center of Bridgewater. From Bridgewater, Route 28 used the main road to Brockton (Main Street). In Brockton, Route 28 shifted slightly west to use Warren Avenue (between Clifton and Pleasant streets) and North Main Street (to the town of Avon). From Randolph, it then went along the alignment of the old Blue Hill Turnpike but left the turnpike alignment before reaching Milton Village, shifting westward to a section of the Brush Hill Turnpike (Blue Hill Avenue) in Mattapan. In Mattapan, it joined with New England Route 6 (modern Route 203) and went west along Morton Street and the Arborway until they met with New England Route 1 at Centre Street in Jamaica Plain.