Arrowe Park Hospital is barely a mile from the centre of the village, and includes an Accident and Emergency department. Upton is served by Upton Group Practice, a dentist and two opticians. Pharmacies in the village include Boots Pharmacy and Numark, as well as further pharmacies at Upton Group Practice and Arrowe Park Hospital. Upton is also served by several residential, care and nursing homes, one of which is situated at Upton Manor and another on Ford Road, as well as a recently built care home on Salacre Lane.