During the 1960s, she participated in the civil rights and anti-Vietnam War movements; in the late 1960s, she was a founding member of radical feminist organizations such as New York Radical Women and W.I.T.C.H. She founded or co-founded the Feminist Women's Health Network, the National Battered Women's Refuge Network, Media Women, the National Network of Rape Crisis Centers, the Feminist Writers' Guild, the Women's Foreign Policy Council, the National Museum of Women in the Arts, the Sisterhood Is Global Institute, GlobalSister.org, and Greenstone Women's Radio Network. She also co-founded the Women's Media Center with activist Gloria Steinem and actor/activist Jane Fonda. In 2018, she was listed as one of BBC's 100 Women.