Hoolahan scored the first goal for Ireland at UEFA Euro 2016 in Ireland's opening group stage match against Sweden. He earned the Man of the Match award for his display in an eventual 1–1 draw. On 22 June 2016, Hoolahan came on as a substitute for James McCarthy in the 77th minute in Ireland's final Euro 2016 group game against Italy. He provided the assist for Robbie Brady's 85th-minute winner to send the Republic of Ireland through to the last 16. Moments prior to the goal, Hoolahan had had a great one-on-one chance which was saved by the Italian goalkeeper Salvatore Sirigu. On 8 February 2018, Hoolahan announced his retirement from international football.