Sailing from Norfolk on 13 January 1945 "Daniel T. Griffin" arrived at Pearl Harbor on 6 February to serve with Underwater Demolition Teams. She cleared on 14 February on convoy duty to Ulithi and Kossol Passage, then arrived at San Pedro Bay, Leyte, on 5 March for invasion rehearsals off Hononhan Island. On 19 March she got underway for Kerama Retto, arriving on the 26th. During the assault on Okinawa, she screened ships at Kerama Retto and swept mines, delivered explosives to the Okinawa beaches, and then acted as rescue ship until 18 May. On 6 April she fought off several suicide attacks destroying at least two enemy planes. When the destroyer was hit "Daniel T. Griffin" protected her against further attack assisted in putting out her fires, and escorted her into Kerama Retto.