During 2009/2010 season, the Levski's team started their European campaign with 9:0 (on aggregate) in the second Qualifying round of Champions League against UE Sant Julià. Topuzakov re-debut for Levski on 21 July 2009 in the second match of the 2nd Qualifying round of UEFA Champions League, where Levski beaten the team of UE Sant Julià. The result of the match was 0:5 with a guest win for Levski. On the next round, Levski Sofia faced FK Baku. The blues eliminated the team from Azerbaijan with 2:0 (on aggregate). In the play-off round Levski was eliminated by Debreceni VSC with 4:1 (on aggregate). However, Levski qualified for UEFA Europa League.