In September 1965 the 334th relocated to Holmsted AFB because the runway at their home base Seymour Johnson AFB was being re-built. In August the 334th TFS moved to McConnell Air Force Base, Kansas and exchanged their F105Fs for F-105Ds, and flew non-stop to Hickam Air Force Base, then on to Anderson Air Force Base, Guam, and on to Takhli Royal Thai Air Force Base, Thailand. From Takhli combat missions were flown to North Vietnam and Laos. Being on temporary duty, the 334th left their Thuds to be part of the developing 355th Tactical Fighter Wing, and in February 1966 returned to Seymour-Johnson. In January 1968 the 334th went to Korea to support operations during the Pueblo incident. The 334th then returned to Seymour Johnson.