Conrad Weiser was born in 1696 in the small village of Affstätt in Herrenberg, in the Duchy of Württemberg (now part of Germany), where his father (also John Conrad Weiser), as a member of the Württemberg Blue Dragoons, was stationed. Soon after Conrad's birth, his father received a discharge from the Blue Dragoons and moved back to the family ancestral home of Gross Aspach. Fever claimed the life of his mother, Anna Magdalena, in 1709 after war, pestilence, and an unusually cold and long winter ravaged the lands. Wallace notes that Conrad Weiser (senior) wrote for his children, "Buried beside Her Ancestors, she was a god-fearing woman and much loved by Her neighbors. Her motto was Jesus I live for thee, I die for thee, thine am I in life and death."