In 2017, Medusa appears in an early adventure with the Frightful Four, published as Avengers 1.1- 5.1 This five issue mini-series is positioned between "Avengers" (vol. 1) #16 & 17, as a side story when the evil team thinks they have killed the Fantastic Four (in "Fantastic Four" #38) but no one knows it. They publicly attack Captain America and his new team of replacements after their press conference to earn some "street cred". They are publicly beaten in a rematch in issue 4.1 but Medusa presumably flees before the team's final cameo in 5.1 where they are preparing a grave for her as a "traitor".