Kotchman missed 128 games in , as he was kept away from the field with complications stemming from mononucleosis. After a spring in which the Opening Day starting first baseman batted better than .400, he hit just .152 with one home run and six RBI in 29 games with the Angels. Kotchman tried to return to the field, but his rehab assignment was cut short when he experienced dizzy spells in July while playing for Triple-A Salt Lake. He spent much of the rest of the season at home in Florida, performing cardio exercises.