After receiving the tributary Wilson Creek, the Lackawanna River continues flowing southwest alongside Pennsylvania Route 171 and soon enters Carbondale. After flowing for several tenths of a mile through Carbondale, the river turns south for a few tenths of a mile, receiving the tributary Racket Brook from the and crossing Pennsylvania Route 106 and a spur of US Route 6. It then turns west-southwest for several tenths of a mile and receives the tributary Fall Brook from the right before turning southwest for several miles. In this reach, the river passes through Carbondale Township and enters Mayfield. It eventually enters Jermyn, where it crosses Pennsylvania Route 107 and receives the tributary Rush Brook from the right. The river then turns south for a few miles, receiving the tributary Aylesworth Creek from the left and entering Archbald. In Archbald, it continues flowing south, receiving the tributaries White Oak Run and Laurel Run from the left. Several tenths of a mile downstream of the latter tributary, it enters Jessup and turns abruptly west.