The "S. haemolyticus" strain JCSC1435 genome contains a 2,685,015 bp chromosome and three plasmids of 2,300 bp, 2,366 bp, and 8,180 bp. The chromosome is comparable in size to those of "S. aureus" and "S. epidermidis" and contains a similar G+C content. In addition, a large proportion of the open reading frames (ORFs) are conserved across all three species. On average, orthologous ORFs are 78% identical. However, "S. haemolyticus" does have unique chromosome regions distributed near "oriC" (the origin of chromosomal DNA replication), and these regions are collectively referred to as the “oriC environ”.