A long time fan of Boston band Buffalo Tom, O'Malley is a close friend of lead singer Bill Janovitz. They have often supported causes together. O'Malley requested that the band create a title song for his own short-lived television show "The Mike O'Malley Show", as well as for the sitcom "Yes, Dear" which he co-starred on. According to O'Malley, his love of the band was shared with his wife and was "the glue" that kept them together during their long distance relationship.