Higuita's first major tournament was the 1989 Copa América, where the team was knocked out in the first round. In the 1990 FIFA World Cup, he played an important part to lead the country into the round of 16 for the first time ever. However, Higuita's unorthodox playing style caused a mistake by him that knocked Colombia out of the World Cup, when he tried to feint Cameroon striker Roger Milla but failed, and Milla dispossessed him and scored, which put Cameroon through to the quarter-finals. Higuita described it as "a mistake as big as a house". As a result of such behaviour, Higuita was nicknamed "El Loco" ("The Madman").