Beginning at an intersection with Marmion Avenue, the highway extends Eastwards to Mitchell Freeway with at-grade intersections into North Beach Road, Everingham Street, Okely Road and Duffy Road. The Mitchell Freeway interchange is a modified diamond interchange consisting of dual two-lane bridges over the freeway and railway line with two parclo cloverleaf loops serving the Reid-westbound to Mitchell-northbound traffic as well as that of the southbound entrance. The eastern half of the interchange also has connects to Balcatta Road, similar to the Great Eastern Highway/Brearley Avenue Interchange prior to the modifications made in 2018. As the interchange is built on a reservation with the capacity to be expanded into a full freeway to freeway interchange, this connection is likely to be removed when this occurs. Further on from the Mitchell/Reid Interchange, there is an at-grade intersection with Erindale Road. This intersection marks the western terminus of the freeway standard section of Reid Highway, with a diamond interchange at Wanneroo Road, which goes over Reid Highway. Conversely, the diamond interchanges at Mirrabooka Avenue, Alexander Drive and Malaga Drive all see the highway travelling over the top of the arterial roads.