His biggest break in the United States came in 1978 when NBC and Mark Goodson-Bill Todman Productions cast him for their new show "Card Sharks". Perry hosted the entire NBC version and the two pilots that preceded the series, airing from April 24, 1978, until October 23, 1981. This series helped Perry begin a long association with NBC, lasting more than a decade. Perry was twice considered as host for the daytime and the nighttime revival of "Card Sharks" in 1986, but due to his commitments with NBC and CTV, the daytime version aired on CBS and was given to Bob Eubanks, and the nighttime version was hosted by Bill Rafferty.