Amtrak's New York City–Chicago "Lake Shore Limited" runs along the full route from Buffalo west. The "Capitol Limited" joins in Cleveland at the "Amtrak Connection" from the former PRR C&P line, just east of the present Cleveland Station (MP 181), on its way from Washington, D.C. to Chicago. Passenger trains along the route originally terminated at LaSalle Street Station, but now run to Union Station, switching to the parallel former Pittsburgh, Fort Wayne and Chicago Railway (Pennsylvania Railroad) at a crossover in Whiting, Indiana () to get there.