Webb staged a comeback season in 2006. In the final round at the Kraft Nabisco Championship she holed a 116-yard shot from the fairway to eagle the 18th hole and then birdied the same hole in a sudden-death playoff to beat Lorena Ochoa and win her second Kraft Nabisco Championship. She won four other tournaments including the Evian Masters and Mizuno Classic. Her 2006 Kraft Nabisco win took her into the top ten of the Women's World Golf Rankings for the first time since they were introduced in February 2006.