Bell Calloway began her acting career in the ABC daytime soap opera, "All My Children" in 1985. After moving to Los Angeles in 1986, she began appearing in episodes of prime time shows such as "The Colbys", "Falcon Crest", "227", "China Beach", "A Different World", and "L.A. Law". She made her film debut on "Number One with a Bullet" (1987), before supporting role of Eddie Murphy's character's arranged wife in the 1988 comedy "Coming to America". In 1990, Bell Calloway co-starred alongside Joe Morton in the ABC drama series, "Equal Justice". During the 1990s, Bell Calloway had number of supporting roles in films, including "What's Love Got to Do with It" (1993) opposite Angela Bassett, "The Inkwell" (1994), and "Crimson Tide" (1995) as Denzel Washington's character wife. She also voiced main role in the 1992 animated comedy, "Bébé's Kids". Bell Calloway also had number of leading and supporting roles in the made for television movies. In 1995, she co-starred opposite James Earl Jones and Joe Morton in the short-lived CBS prime time soap opera, "Under One Roof", the first drama series that feature an African-American lead characters. For her role on the series, Calloway was nominated for the NAACP Image Award for Outstanding Actress in a Drama Series. She also had the leading roles on the short-leved NBC sitcom "Rhythm & Blues" (1992–93), and starred alongside Larry Hagman as his girlfriend in the CBS drama "Orleans" (1997).