Sinise first starred in a film when he directed, produced, and starred in the film adaptation of John Steinbeck's classic novel 'Of Mice and Men'. Sinise played George Milton alongside John Malkovich who played Lennie. Subsequent roles include Lieutenant Dan Taylor in "Forrest Gump" (1994), for which he was nominated for the Academy Award for Best Supporting Actor, Harry S. Truman in "Truman" (1995), for which he won a Golden Globe, Ken Mattingly in "Apollo 13" (1995) and Detective Jimmy Shaker in "Ransom" (1996).