Cerci made his debut for Fiorentina in the 29 August 2010 match against Napoli, ending 1–1, and scored his first goal in Serie A on 7 November 2010 against Chievo (1–0). Near the end of the season, Cerci scored six goals in five games, with two braces. He concluded the season with 26 appearances and seven goals in the league, plus one goal in Coppa Italia against Reggina. However, Cerci had a difficult rapport with Fiorentina and its supporters. During his time at Florence, he was accused of overindulging in the city nightlife and was famous for illegally parking his Maserati around the city centre. On one occasion, he was fined for refusing to move his car after he parked it in a space reserved for police.