It was in this context that the so-called American School of Anthropology thrived as the champion of polygenism or the doctrine of multiple origins—sparking a debate between those influenced by the Bible who believed in the unity of humanity and those who argued from a scientific standpoint for the plurality of origins and the antiquity of distinct types. Like the monogenists, these theories were not monolithic and often used words like races, species, hybrid, and mongrel interchangeably. A scientific consensus began to emerge during this period "that there exists a Genus Homo, embracing many primordial types of 'species'". Charles Caldwell, Samuel George Morton, Samuel A. Cartwright, George Gliddon, Josiah C. Nott, and Louis Agassiz, and even South Carolina Governor James Henry Hammond were all influential proponents of this school. While some were disinterested scientists, others were passionate advocates who used science to promote slavery in a period of increasing sectional strife. All were complicit in establishing the putative science that justified slavery, informed the Dred Scott decision, underpinned miscegenation laws, and eventually fueled Jim Crow. Samuel G. Morton, for example, claimed to be just a scientist but he did not hesitate to provide evidence of Negro inferiority to John C. Calhoun, the prominent pro-slavery Secretary of State to help him negotiate the annexation of Texas as a slave state.