Repaired at the Norfolk Navy Yard, "Saratoga" was recommissioned in 1847, Commander David G. Farragut in command. Assigned to the Home Squadron, she rounded Cape Henry on 29 March, sailed south along the coast, entered the Gulf of Mexico, and joined Commodore Perry's Home Squadron off Veracruz, on 26 April. Three days later, the sloop-of-war was ordered to proceed some 150 miles up the coast to blockade Tuxpan. She reached the station on 30 April and remained there until heading back toward Veracruz on 12 July. About a fortnight later, she got underway for Tabasco, carrying dispatches; remained at that river port but a day, and returned to Veracruz on 11 August. On 1 September, "Saratoga" relieved Decatur at Tuxpan and remained on station there, despite a serious outbreak of yellow fever on board, for about two months before heading back to Veracruz. After a month there, the ship got underway for the Florida coast to land her sick and replenish her stores. She arrived at Pensacola on 6 January 1848; and, after disembarking all the seriously sick patients at the base hospital, got underway north on the last day of the month. She made New York City on 19 February and was decommissioned a week later.