The regiment saw action during Operation Blackcock, the plan to clear the west bank of the Roer of Germans, which commenced on 16 January 1945. It subsequently took part in the crossing of the Rhine, which began on 25 March, with the objective of heading eastward, straight for the city of Hamburg. The regiment was now firmly inside German territory, encountering fierce resistance from the Germans. The regiment took part in the capture of a number of towns during the rapid advance into Germany. In April, the regiment took part in the efforts to capture Ibbenburen, seeing heavy fighting against the fierce defenders. The regiment saw further heavy fighting elsewhere before it, with the rest of its brigade, headed south for Bremen, where they helped capture Wildeshausen. Later, the Inniskillings took part in the successful attack on Soltau before the advance on Harburg, a suburb of Hamburg, resumed. Towards the end of April, the Germans negotiated the surrender of Hamburg, a city that had been devastated by the Allied bombing campaigns; the 7th Armoured Division entered the city on 3 May.