Several celebrities guested as characters in single episodes, such as Dan Aykroyd, John Astin, Jason Alexander, Robert Culp, Cloris Leachman, Rita Moreno, Robert Urich, Wallace Shawn, Joan Van Ark, Efrem Zimbalist Jr., George Murdock, Roseanne Barr as Fran's cousin Sheila, Joan Collins as Maxwell's stepmother, Robert Vaughn as Maxwell's father, Twiggy as Maxwell's sister (in her first appearance, in season 1), and Dina Merrill as his mother. Others appeared as themselves, primarily in connection with Maxwell's business relations, such as Bob Barker, Chevy Chase, Robert Culp, Billy Ray Cyrus, Lesley-Anne Down, Erik Estrada, Dan Aykroyd, Joe Lando, Joan Collins, Richard Kline, Bette Midler. Eydie Gormé, Jane Seymour, Dame Elizabeth Taylor, Elton John, Lamb Chop and Shari Lewis, Andrew Dice Clay, Lynn Redgrave, Hugh Grant, Margaret Cho, Jeanne Cooper, Melody Thomas Scott, Eric Braeden, Shemar Moore, Joshua Morrow, Hunter Tylo; media personalities Roger Clinton, Alicia Machado, Jay Leno, David Letterman, Sally Jessy Raphael and Donald Trump; and musicians Ray Charles, Michael Bolton, Patti LaBelle, Lisa Loeb, Eartha Kitt, Brian Setzer, Celine Dion, Rapper Coolio, Whoopi Goldberg, Steve Lawrence, and Rosie O'Donnell. Jonathan Penner appeared as Fran's former fiancé, Danny Imperialli. James Marsden appeared as Maggie's boyfriend, Eddie, and Telma Hopkins appeared as Fran's "mother" in the episode "Fran's Roots". Scott Baio made an appearance as a rookie doctor who was Fran's former schoolmate. Jon Stewart portrayed a Jewish love interest of Fran's until it was discovered at a family wedding that the two were cousins; on the June 29, 2011 airing of "The Daily Show", Stewart stated he agreed to make an appearance after receiving a personal call from Fran Drescher.