Shrewsbury was selected as the keeper of Mary, Queen of Scots, who was imprisoned by Queen Elizabeth I in 1568 after she had escaped to England from Scotland following the disastrous Battle of Langside. Shrewsbury received his ward at Tutbury Castle on 2 February 1569, but in June he removed to Wingfield Manor, whereupon a rescue was attempted by Leonard Dacre. The Earl had several houses and castles in the interior of the kingdom, in any of which Mary might be kept with little danger. In September the household was back again at Tutbury, where an additional guard or spy, temporarily joined the family in the person of Henry Hastings, 3rd Earl of Huntingdon. In November took place the Northern Rebellion, with the revolt of the Earls of Northumberland and Westmorland, who planned to march on Tutbury. Mary was for the time being moved to Coventry, and did not return until the following January.