In "X-Men" 2000 Annual they, like Omega Sentinels, are shown to have limited nano-mechanical morphing abilities. Able to morph or sprout cannon artillery from their body parts for greater arms fire. One of the deadliest abilities of the Prime Sentinels is displayed to be the lethal injection of nanomachines into another human being that will turn the target into a Prime Sentinel. It can be noticed that in the selfsame episode Rogue tries to use her personality-absorbing powers on one of the Prime Sentinels only to find nothing at all: she then states that nothing of the original host remains once the Prime Sentinel personality has taken over, though this is questionable as Magneto and Xavier were able to restore Karima's personality.