In 2009–10 season, "La Viola" signed Marco Marchionni, made Santana at first became a backup player, likes the first group stage of 2009–10 UEFA Champions League match against Lyon, substituted Marchionni in the 72 minutes. He started the third group stage match, as Marchionni was rested. In the 4th match he lost his starting place again, to Marchionni. He substituted Juan Vargas in the 77th minutes in that match. In the last 2 match of the group stage, Santana played a new role, as attacking midfielder, as Adrian Mutu was rested.