Charlemagne Tower was born on April 18, 1809 in Paris, Oneida County, New York, the eldest of the eight children of Reuben Tower, a New York State Legislator, and Deborah Taylor Pierce. Tower took his early schooling at the Oxford Academy, and then at the Clinton and Utica Academies. In 1824, at the age of 14, Tower taught school in Oneida County. The next year, he was made an assistant teacher at the Utica Academy. Tower entered Harvard in 1827, and graduated in 1830.