In the early days, his guitar tone derived from a modified Marshall JCM800 head with scooped mids and high treble settings to produce the thrashy, chugging tone which has been so influential to the metal genre. After it was stolen, he switched to the Line 6 POD Pro with a Mesa/Boogie tube power amp. This setup was used to record Digimortal. Currently with Fear Factory, Cazares endorsed the Line 6 Vetta II HD and POD X3 Pro processor with a Mesa/Boogie tube power amp with Mesa/Boogie oversized Rectifier 4x12 cabinets. When playing live, Cazares mostly uses the speaker cabinets for monitoring, or does not use them at all, since his signal is also run into the venue's PA. In 2011, Cazares replaced the POD X3 Pro for the most recent version, the POD HD Pro. He has also replaced his Mesa/Boogie tube power amp for a Matrix GT800FX 800W solid state power amp, and his Mesa/Boogie Rectifier 4x12 for a custom-built cabinet built by David Laboga. Sometime in 2012 or 2013, Cazares eventually switched from Line6 to Fractal Audio, making use of their Axe-FX II. This was short lived, as he would soon switch to using a Kemper Profiling Amp, an amplifier that could "profile" other guitar amps, allowing him to get a tone similar to previous albums.