Quintero made his first appearance of the 2009–10 season in a North American SuperLiga match on 28 June 2009. Quintero came on as a substitute in the second half and helped Santos secure a 3–1 win over the Kansas City Wizards in the final match of the group stage. He would play the full 90 minutes and score once in the semifinal with Tigres UANL, however "Los Guerreros" would fall by the score of 3–2. He made his first Primera División appearance of the season season in the first match of the Apertura on 26 July, a 1–1 draw with Monarcas Morelia. He picked up his first goal of the Apertura campaign on 16 August in a 3–2 win over Cruz Azul. Quintero recorded his first assist of the season on 4 September in a 4–2 victory over Estudiantes Tecos. After scoring a goal in a 2–0 win over Querétaro on 13 September, Quintero got an assist in the 88th minute to give Santos a 1–0 over Atlante. He had another assist in the next match for "Los Guerreros" as they defeated Pachuca 4–0. Quintero ended the Apertura with 3 goals and 5 assists as helped Santos qualify for the Liguilla. Santos were defeated by Morelia in the first round, losing 4–2 over the two legs. In the 2010 InterLiga Quintero made 3 substitute appearances as Santos were eliminated in the group stage. In the opening match of the 2010 Clausura, Quintero came off the bench and scored to help Santos record a 3–2 victory over Morelia. He scored in three consecutive games from matchweek 9 to 11, with Santos winning all three games. On 19 April, he scored and assisted another as "Los Verdiblancos" defeated San Luis 2–1. Quintero scored 6 times and assisted for 4 goals as Santos qualified for Liguilla. He picked up an assist in the first leg of the quarterfinals as Santos went on to defeat UNAM Pumas 2–1 over two legs. Quintero had another assist in the first leg of the semifinals and scored for himself in leg two as "Los Guerreros" defeated Morelia 10–4 on aggregate. He scored again in the first leg of the final, but Santos would lose on penalties after leg two, with Toluca winning their 10th league title in club history.