While on an embassy to France in 1541 William Howard was charged with concealing the sexual indiscretions of his young niece, Catherine Howard, Henry VIII's fifth wife, and was recalled to England to stand trial. On 22 December 1541 Howard, his wife, and a number of servants who had been alleged witnesses to the Queen's misconduct were arraigned for misprision of treason, convicted, and sentenced to life imprisonment and loss of goods. He and most of the others were pardoned after Queen Catherine's execution on 13 February 1542.