Before entering the town of Tijeras, there is a former location of a "musical road" feature where rumble strips were arranged to play America the Beautiful for eastbound travelers. Once in Tijeras itself, the highway intersects NM 337, which travels to the southeast, and NM 14, which heads northeast to Santa Fe. Continuing east, NM 333 travels through Sedillo, where it intersects the former NM 306 and NM 217. The highway then leaves Bernalillo County, and enters Santa Fe County and the town of Edgewood, where it intersects NM 344. Shortly thereafter, the highway enters Torrance County and the city of Moriarty, where it ends at an intersection with I-40 Business (I-40 Bus.).