She supported the Allied landings in North Africa in November 1942 and served with the 10th Destroyer Flotilla at Plymouth. "Eskimo" was extensively damaged when two German dive bombers attacked her in the Mediterranean while taking part in Operation Husky. She cornered and sank the enemy German submarine while in company with the Canadian destroyer and a Liberator aircraft of the Czech air force in the English Channel north of Brest on 24 June 1944. During the final days of the war, she operated in the Far East.