It is thought that the slime molds in the third universe are agents for the aliens that attack the city, as two characters are seen under control of something that acts much like Fred when he takes over someone. In addition, when the two characters are knocked unconscious, two objects detach from their heads and enter a grate, leaving behind a trail of slime. Also, when the Evil Nick shows the good Nick around his base, he takes him to a room where medical help is being given to a man with blue slime dripping from his head and neck, which Fred and Persephone regularly excrete when they come in contact with something. Finally, Fooker points his gun at Persephone during the alien attack and orders her to return to Ki's purse, possibly fearing that she will be mistaken for an enemy and killed.