Mission San Luis de Apalachee (also known as San Luis de Talimali) was a Spanish Franciscan mission built in 1633 in the Florida Panhandle, two miles west of the present-day Florida Capitol Building in Tallahassee, Florida. It was located in the descendent settlement of Anhaica (also as Anhayca Apalache or Inihayca) capital of Apalachee Province. The mission was part of Spain's effort to colonize the Florida Peninsula and to convert the Timucuan and Apalachee Indians to Christianity. The mission lasted until 1704 when it was evacuated and destroyed to prevent its use by an approaching militia of Creek Indians and South Carolinians.