C2C suggests that industry must protect and enrich ecosystems and nature's biological metabolism while also maintaining a safe, productive technical metabolism for the high-quality use and circulation of organic and technical nutrients. It is a holistic, economic, industrial and social framework that seeks to create systems that are not only efficient but also essentially waste free. Building off the whole systems approach of John T. Lyle's regenerative design, the model in its broadest sense is not limited to industrial design and manufacturing; it can be applied to many aspects of human civilization such as urban environments, buildings, economics and social systems.