After Leo Varadkar was appointed Taoiseach, by the President of Ireland, as part of his new cabinet, Coveney was appointed Minister for Foreign Affairs and Trade, with special responsibilities for Brexit. Coveney replaced Charles Flanagan, who became Minister for Justice and Equality. It was understood Coveney heavily lobbied Varadkar for the role as he wanted a large role on Brexit. In his capacity as Minister, he has also been co-chairing the European People's Party (EPP) Justice and Home Affairs Ministers Meeting since 2018, alongside Esteban González Pons.