Vinci began her clay-court season at the Porsche Tennis Grand Prix. In the first round, Vinci lost to newly returned Maria Sharapova, 5–7, 3–6. Vinci had her first win since Indian Wells at the Madrid Open by defeating Daria Kasatkina in the first round, 6–1, 1–6, 6–1. In the second round, she lost to 3rd seed and eventual champion Simona Halep, 3–6, 6–2, 6–7. Vinci led 3–6, 6–2, 5–2 before Halep came back to win the match. At the Internazionali BNL d'Italia, she lost in the first round to Ekaterina Makarova, 2–6, 1–6. As the 31st seed at the French Open, Vinci was defeated in the first round by the previous year's Olympic gold medalist Monica Puig, 6–3, 3–6, 6–2.