After the death of Alexander the Great in 323 BC, his generals immediately began squabbling over his empire. Soon it degenerated into open warfare, with each general attempting to claim a portion of Alexander's vast kingdom. One of the most talented generals among the Diadochi was Antigonus Monophthalmus ("Antigonus the One-eyed"), so called because of an eye he lost in a siege. During the early years of warfare between the Successors, he faced Eumenes, a capable general who had already crushed Craterus. The two Diadochi fought a series of actions across Asia Minor, and Persia and Media before finally meeting in what was to be the last clash at Gabiene ().