Andújar began seeing more work out of the bullpen in and earned his first career save on August 25 against the Pittsburgh Pirates. He began the season in the bullpen and was 4–2 with a 3.23 ERA with three saves and two blown saves when he was added back to the starting rotation. He responded with four consecutive complete game victories in which he gave up just one earned run per game. He was named to his second National League All-Star team and pitched two innings while giving up two runs (one earned). On August 14, he pitched a four-hit complete game against the Montreal Expos while hitting an inside-the-park home run to account for both of the Astros' runs in a 2-1 win.