She began her American hard court swing in Carlsbad as the 9th seed. She was upset in the second round by Zheng Jie. Vinci scored the biggest win of her career in Toronto, beating defending champion and world No. 1, Caroline Wozniacki, 6–4, 7–5, in the second round of the Canadian Open. In the second set, Vinci rallied from 1–5 down and saved multiple set points, before going on to win the match. In the third round, she defeated former world No. 1, Ana Ivanovic, 7–6, 6–2. She lost in the quarterfinals to 10th seed Sam Stosur, 4–6, 1–6.