De Man's early life was difficult and shadowed by tragedy. His mother Madeleine's first pregnancy with her oldest son Hendrik ("Rik," b. 1915) coincided with the intense German bombings of World War I and strained her physical and mental health. The stillbirth of a daughter two years later pushed her into intermittent but lifelong suicidal depression. She was psychologically fragile and had to be watched. The family walked on eggshells and "Bob" de Man found solace with other women. In contrast to Rik, who was backward and a failure in school, Paul dealt with his difficult home life by becoming a brilliant student and accomplished athlete. He was enrolled in the Dutch-speaking cohort of boys admitted to the prestigious and highly competitive Royal Athenaeum of Antwerp. There, he followed his father's career path in choosing to study science and engineering, consistently receiving top marks in all subjects and graduating at the top of his class. He took no courses in literature or philosophy but developed a strong extracurricular interest in both as well as in religious mysticism. In 1936, his brother Rik de Man was killed at the age of 21 when his bicycle was struck by a train at a railroad crossing. The following year, it was Paul, then seventeen, who discovered the body of their mother, who had hanged herself a month before the anniversary of Rik's death.