2007 brought great prospects early on. Colin entered his second of a two-year deal with Yamaha factory team, now known as Fiat Yamaha riding the new Yamaha YZR-M1 800cc. Yet after starting second on the grid in Istanbul, a first lap crash caused by Olivier Jacque took him out. At Le Mans Colin took pole position, but made a slow start and gambled on switching to wet tyres in damp conditions. He did this too early, and by the time it was wet enough his tyres had shredded, forcing him to pit again and finish at the back of the field.