The World Series against the Kansas City Royals went poorly for Andújar. He lasted 4+ innings in Game 3 and took the loss opposite a dominant Bret Saberhagen. John Tudor, meanwhile, was 3–1 with a 1.59 ERA that postseason, leading Cardinals manager Whitey Herzog to go with Tudor in the decisive Game 7, despite the fact that Andújar had five days' rest. The strategy failed, and Tudor was pulled in the third with the bases loaded and three runs already on the board. The score was 10–0 by the time Herzog brought Andújar in for mop-up duty. When umpire Don Denkinger called a ball, Andújar emphatically showed his disagreement and had to be restrained by teammates. Herzog was furious and was ejected. A pitch later, Andújar was ejected for arguing another pitch which was clearly off the plate. Andujar charged Denkinger, bumping the umpire before being restrained by teammates.