Between Cygnet and Perrysburg it is the relic of an old U.S. Route 25 (US 25) that passes through Bowling Green as largely a divided surface highway. From Perrysburg it crosses the Fort Meigs Memorial (Maumee-Perrysburg) Bridge joint with US 20 and then follows the Anthony Wayne Trail from Maumee into downtown Toledo. The Maumee portion is joint with US 24. (US 24 in greater Toledo takes, as far south as Perrysburg, the path of what used to be U.S. Route 25, more distant from the newer Interstate 75 (I-75), having had its route switched with that of old U.S. Route 25). North of this former terminus, SR 25 runs through downtown Toledo on Erie Street (northbound) and Michigan Street (southbound) before becoming the Greenbelt Parkway, which is cut off at I-280, terminating the route.