The mid-decade redistricting resulted in the election of George H. W. Bush, a former Chairman of the Harris County Republican Party and the son of former Connecticut U.S. Senator Prescott Bush, and who unsuccessfully sought the state's Class 1 Senate seat against Democrat Ralph Yarborough in 1964. Bush would go on to hold the district for two terms before making an unsuccessful run for the United States Senate in 1970, losing to Lloyd Bentsen who defeated Yarborough in an upset in the Democratic primary. Bush would eventually go on to become Vice President under Ronald Reagan and in 1988 would be elected President. After losing the 1992 election to Bill Clinton, Bush would retire to the 7th where he continued to reside until his death in 2018.