Savage opened two galleries whose shows were well attended and well reviewed, but few sales resulted and the galleries closed. The last major showing of her work occurred in 1939. Deeply depressed by her financial struggle, in the 1940s Savage moved to a farmhouse in Saugerties, New York. While in Saugerties, she established close ties with her neighbors and welcomed family and friends from New York City to her rural home. Savage cultivated a garden and sold pigeons, chickens, and eggs. The K-B Products Corporation, the world's largest growers of mushrooms at that time, employed Savage as a laboratory assistant in the company's cancer research facility. She acquired a car and learned to drive to enable her commute. Herman K. Knaust, director of the laboratory, encouraged Savage to pursue her artistic career and provided her with art supplies. Savage created and taught art and sculpted friends and neighbors. Her last commissioned work was for Knaust and was that of the American journalist and author Poultney Bigelow, whose father, John, was U.S. Minister to France during the Civil War.