During the First World War, many of the male surgical staff were deployed on foreign active service and Dr. Aldrich-Blake took on increased responsibility for the surgery, becoming consulting surgeon to the hospital. Aldrich-Blake spent multiple holidays aiding the military hospitals in 1914 to 1916, specifically in France with Dr. Frances Ivens from the Anglo-French Red Cross Hospital and helped out as a visiting surgeon at the Women's Army Auxiliary Corps Hospital. Aldrich-Blake was nicknamed "Madame la Générale" by her patients. Her time was also spent contacting other women in the profession to organise volunteer units. She approached every woman on the Medical Register to ask if they would consider volunteering for the Royal Army Medical Corps, and 48 enrolled, many of whom were sent to Malta.