Hostile native tribes and distance from nearby Spanish colonies discouraged settlers from moving to the area. It was one of New Spain's least populated provinces. In 1749, the Spanish peace treaty with the Lipan Apache angered many tribes, including the Comanche, Tonkawa, and Hasinai. The Comanche signed a treaty with Spain in 1785 and later helped to defeat the Lipan Apache and Karankawa tribes. With more numerous missions being established, priests led a peaceful conversion of most tribes. By the end of the 18th century only a few nomadic tribes had not converted to Christianity.