Following "The Facts of Life," McKeon was courted by NBC executives for the title role in the TV sitcom adaptation of the 1988 film "Working Girl"; the role, played by Melanie Griffith in the movie, instead went to then unknown Sandra Bullock. In 1994, McKeon and Courteney Cox auditioned for the role of Monica Geller on "Friends." The role went to Cox. When asked in interviews about the audition, McKeon said, "I have no hard feelings. The role went to the right person. Courteney was brilliant. Now, I can't see anybody playing the role, not even myself." In 1995, she starred in her own series, "Can't Hurry Love," which lasted one season. In 1998, she starred with Jean Smart in the sitcom "Style & Substance." McKeon portrayed Inspector Jinny Exstead on the Lifetime police drama "The Division" from 2001 to 2004, with her pregnancy incorporated into the storyline of the last year of the series. From 2009 to 2010 she appeared in a recurring role in the Disney Channel Original Series "Sonny with a Chance," as Connie Munroe, the mother of Demi Lovato's title character.