He moved with his family to London in 1820, apparently discontented with rural life and wishing to seek his fortune. The family settled at 7 Argyle Street, near Hanover Square, where Gurney continued his practice as a surgeon. There he expanded his scientific knowledge and started giving a series of lectures on the elements of chemical science to the Surrey Institution, where he was appointed lecturer in 1822. A son, Goldsworthy John, was also born to the couple in that year, at Launcells (later to die relatively young in 1847).