McCann was again selected for the All-Star Game in 2009 and 2010. In the latter, he was named the MVP after driving in all three of the National League's runs with a bases-clearing double in the seventh inning (driving in Scott Rolen, Matt Holliday, and Marlon Byrd), off of Chicago White Sox reliever Matt Thornton, giving the NL a 3–1 victory, its first in the midsummer classic since 1996. On August 23, McCann hit the first walk-off home run reviewed by instant replay. McCann hit a line drive to right field. The ball struck the top of the right field wall. The umpires called it a double, but McCann and Braves bench coach Chino Cadahia argued the call. The umpires went to go review instant replay. Replays showed that the ball struck the top of the right field wall, bounced into the stands, and then got onto the field. Thus, the umpires overturned the call and called it a walk-off home run. In 2010, he allowed more stolen bases than any other NL catcher, with 84.