At the test held immediately following the Valencia round, Stoner was once again fastest while testing the new 2010 version of the Desmosedici. However, Rossi was fastest in five of the six pre-season tests. Stoner qualified on pole for the season opener in Qatar, and was leading the race when he crashed out, later acknowledging that this was his own mistake. He also crashed out of round 3 at Le Mans, this time attributing the crash to the front of the bike unloading when not running at maximum pace. His first podium of the year came at Assen, despite struggling with arm pump late in the race.