The future Clay County had been inhabited for thousands of years by indigenous people (the remains of an Indian village's burial ground are still visible west of Ingraham). White explorers used or cleared a trail between the future settlements of Saint Louis in Missouri, to Vincennes in Indiana; this became a mail route in 1805. The first white settler (McCauley, from Kentucky) built a cabin in 1809 near this road at its intersection with a trail from Vandalia to Mt. Carmel. He was driven out by the Indians, but had returned by 1819, by which time other cabins had been constructed in the area, which was originally called Habbardsville. The Indians were removed from the area in 1828.