After crossing an intersection with Genesee Street, NY 240 continues north through Cheektowaga, passing east of Buffalo Cemetery and west of Pine Lawn Cemetery. A short distance north, the route passes east of Ridge Lawn Cemetery, crossing under NY 33 (the Kensington Expressway). Near the underpass, NY 240 intersects with several ramps from the expressway. After NY 33, the route passes east of Mount Calvary Cemetery before entering a large residential neighborhood. Continuing north through Cheektowaga, NY 240 becomes a two-lane residential street, intersecting with CR 141 (Cleveland Drive) at a rotary. Continuing northward, NY 240 enters the town of Amherst, where it enters two more rotaries, with CR 290 (Wehrle Drive) and CR 208 (Kensington Avenue).