Major alterations to the course were necessary for 2006 as USA Track and Field had to measure a new course to reflect the opening of the Arthur Ravenel, Jr. Bridge and construction on the Ansonborough Fields complex resulted in the moving of the finish line away from Alexander Street, where it had been set since 2000, and a new finish line at George Street and Meeting Street, across from the Carolina First Arena in Charleston, was established. The finish festival was held at Marion Square, which is located a short walk as runners made the cooldown from the finish line.