Construction of Axioupolis' first church, Saint Dimitrios (Greek: Αγίου Δημητρίου), started in 1843 after Christians were given the right to build churches and schools by the Ottomans. Saint Dimitrios was completed in 1859. During the national competitions in the area, a lot of locals resisted in the Internal Macedonian Revolutionary Organization (IMRO), while others participated in the struggle led by IMRO. A committee of IMRO was founded in Boymitsa in 1896. Its leader was the local Bulgarian teacher Filip Dimitrov. Dellios Petkou Topalis killed in 1898 by Bulgarians.