Stretching from Pisac to Ollantaytambo, this fertile valley is irrigated by the Urubamba River. The Chanapata civilization first utilized this area starting at around 800 BCE because of the rich soil used for agriculture. The Qotacalla civilization lived in the Sacred Valley from 500 to 900 CE The Killke civilization then lived in the Sacred Valley from 900 CE until the Incan Empire took over the region in 1420. The Incan Empire ruled this area until the arrival of the Spanish.