Taking over after series creator Brian K. Vaughan completed his run on the series, Whedon became the second writer of the Marvel comic "Runaways". Having already been a committed reader, he had a letter published in the first volume, which was included in the Volume 1 hardcover edition. He also wrote short pieces for "Stan Lee Meets Spider-Man" and "Giant-Size Astonishing X-Men" #1, and he was the subject of an issue of the comic book, "Marvel Spotlight" (alongside artist Michael Lark). As part of a panel of writers, he contributed to Marvel Comics' "Civil War" crossover event lending advice on how to tell the story and also how to end it. In March 2016, Whedon contributed a story for the 75th anniversary issue of "Captain America: Sam Wilson" with "Astonishing X-Men" collaborator John Cassaday. He introduced several new characters into the Marvel Universe such as the villainous Ord, X-Men Ruth "Blindfold" Aldine and Hisako "Armor" Ichiki, Runaway Klara Prast, and Special Agent Abigail Brand along with S.W.O.R.D., the organization Brand commands.