Street missed the first two-and-a-half months of the season of the 2010 season with shoulder soreness, but on returning to the team he assumed the role of closer. Prior to a game on July 26, 2010, Street was struck in the midsection by a line drive during batting practice. He fainted several times from the pain and needed to be taken off the field in an ambulance, but he avoided the disabled list. Street finished 2010 with 20 saves in 25 opportunities and a 3.61 ERA.