When the original state trunklines were designated, an M-11 ran the length of the Lake Michigan shoreline from the Indiana state line to Mackinaw City. That highway was replaced in 1926 by two of the then-newly created US Highways. A second highway was given the M-11 designation at that time in the Saline area. This highway was removed from the highway system and the designation decommissioned in 1954. The current M-11 was designated in 1961 along a set of roads in the Grand Rapids area that includes portions of a former route of US Highway 16 (US 16) in Michigan.