In 1622 Wentworth's first wife Margaret Clifford died. Wentworth, according to his friends, was deeply grieved by her death; but in February 1625 he married Arabella Holles, daughter of John Holles, 1st Earl of Clare and Anne Stanhope: a marriage which was generally believed to be a true love affair on both sides. He represented Pontefract in the Happy Parliament of 1624, but appears to have taken no active part. He expressed a wish to avoid foreign complications and "do first the business of the commonwealth".