For many centuries, Niedernberg lay far from any main trade road and led a rather sheltered life. The only link between the Spessart and the Odenwald was the Main ferry, which was withdrawn in 1994. In the meantime, however, Niedernberg has undergone sweeping structural development and of the original pastoral idyll almost nothing is left. With the direct link to the Autobahn to the Frankfurt Rhine Main Region, the completion of a great industrial-commercial area and the Main Bridge, finished in 2001, the environment became conducive to attracting various employers to the municipality. Leaders among these are currently the electronics and computer field, and also concrete processing.