In late September 1869 she developed high fevers for which medical remedies could do little and she died as a result before midnight on 8 December 1869; upon her death a nun reported a pleasant and sweet odor filling the room that Martillo had died in. She died upon the opening of the First Vatican Council. Her remains were deemed upon exhumation to be incorrupt in 1955, and were transferred from Peru back to her homeland of Ecuador until 1972, when moved to her village of Nobol. On 22 August 1998 a shrine in her honor was dedicated in Nobol where her remains now rest.