Street continued to serve as the closer for the A's in 2006. He finished the season with a 4-4 record, 37 saves, 67 strikeouts, a 3.31 ERA in 70.2 innings pitched, and 11 blown saves. On October 14, Street gave up a walk-off three-run home run to Magglio Ordóñez of the Detroit Tigers in Game 4 of the 2006 ALCS that ended the A's postseason. Street had a solid season in 2007, despite missing time with an injury. He went 5–2 with a 2.88 ERA, with 16 saves and 62 strikeouts in 50 innings. Street struggled somewhat with a nagging injury in 2008. After a rough stretch in July and August, he lost his closer position to rookie Brad Ziegler. Street's health and pitching improved, although Ziegler continued to close.