Lope de Vega is said to have "perfected" the Spanish comedia, but also wrote autos. The drama of the Spanish Golden Age is often characterized by his work so that pre- Lope de Vega drama of the 16th century is said to have used the introito which was soon replaced by the loa. His loas tend to have little evident relation to the play that follows and are characterized by their playful, humorous, trivial and positive ending appeal to the audience for the rest of the performance. Lope de Vega's loas vary from 100 to 400 lines and he is thought to have written many, but nearly all have been lost.