Knopf was introduced to his future wife and business partner, Blanche Knopf, at a party at the Lawrence Athletic Club in 1911. Their relationship was built on their mutual interest in books. Blanche said of their relationship, "Alfred had realized I read books constantly and he had never met a girl who did ... I saw him and we did was talk books, and nobody liked him--my family least of all. But I did, because I had someone to talk books to and we talked of making books...We decided we would get married and make books and publish them." Alfred and Blanche were married on April 4, 1916.