The ship returned to New England in early May, where she remained until September training reservists and engaging in division maneuvers. Arriving at Charleston, South Carolina on 22 September, "Hopewell" carried out similar operations out of the South Carolina port, returning to New York in May 1921 for reserve training. Sailing from Newport, Rhode Island on 10 October, the destroyer was placed in reserve at Charleston until 10 April, when she departed for Philadelphia, Pennsylvania. "Hopewell" decommissioned there on 17 July 1922.