During his career as jurist, he has heard and led high-profile cases, including the case of the suspension of Iftikhar Muhammad Chaudhry, a fellow chief justice, and the trial of missing persons in 2012. His credentials led to the government appointing him as a chairman of the Abbottabad Commission to find out the preludes and causes of the 2 May 2011 military raid that caused the death of Osama Bin Laden, conducted by the United States in Abbottabad, Pakistan. After carefully studying the case, Iqbal authored the Abbottabad Commission Report over this issue which was submitted to the Prime Minister of Pakistan in 2013.