In 2004, she won the North Urals Cup, the second international super-tournament for female chess players. Held in Krasnoturinsk, the nine-round single round-robin tournament featured ten of the strongest female players in the world. Skripchenko finished a half point ahead of Maia Chiburdanidze, the former Women's World Champion, and also defeated her in their individual encounter. In 2005, she won the Accentus Ladies Tournament in Biel. Skripchenko reached the quarter-finals at the Women's World Chess Championship in 2000, 2001 and 2010.