In his 14 NFL seasons, Lott recorded 8.5 sacks and 63 interceptions, which he returned for 730 yards and five touchdowns. He recovered 17 fumbles, returned them for 43 yards, and gained 113 yards on kickoff returns. Lott also played in 20 postseason games, recording nine interceptions, 89 tackles, one forced fumble, one fumble recovery, and two touchdowns. Additionally, he was named All-Pro eight times, All-NFC six times, and All-AFC once. Beyond statistics, Lott had an uncanny awareness of how a play was developing, which allowed him to break up passes and earn a reputation as one of the hardest and most efficient open-field tacklers in the history of the league.