The Clear Range is largely the domain of the Nlaka'pamux peoples, although the northwest edge of the range is occupied by communities of the St'at'imc people and a rancherie of the Bonaparte River band of the Secwepemc people at Marble Canyon, whose territory also includes southeastern portion of the range along the Thompson. There are no urban settlements or towns in the range although it is skirted by three major highways and also three rail lines (the BCR, CPR and CNR).