The high generation of waste biomass is an attractive source for conversion to valuable products, several biorefinery routes has been proposed to upgrade waste streams in valuable products. The production of biogas from banana peel (Musa paradisiaca) under the biorefinery concept is a promissory alternative since is possible to obtain biogas and other co-products including ethanol, xylitol, syngas, and electricity; this process also provides high profitability for high production scales. The economic assessment of the integration of organic waste anaerobic digestion with other mixed culture anaerobic fermentation technologies was studied; the highest profit is obtained by dark fermentation of food waste with separation and purification of acetic and butyric acids (47 USD/t of foodwaste). The technical feasibility, profitability and extent of investment risk to produce sugar syrups from food and beverage waste was analyzed; the returns on investment shown to be satisfactory for the production of fructose syrup (9.4%), HFS42 (22.8%) and glucose-rich syrup (58.9%); the sugar syrups also have high cost competitiveness with relatively low net production costs and minimum selling prices. The valorization of municipal solid waste through integrated mechanical biological chemical treatment (MBCT) systems for the production of levulinic acid has been studied, the revenue from resource recovery and product generation (without the inclusion of gate fees) is more than enough to out- weigh the waste collection fees, annual capital and operating costs.