Due to the lack of melanin production in both the retinal pigmented epithelium (RPE) and iris, those affected by albinism sometimes have pink pupil due to the underlying blood vessels showing through. However, this is not always the case and many albino animals do not have pink pupils. The common belief that all albinos have pink pupils results in many albinos being incorrectly labeled as 'leucistic'. The neural crest disorders that cause leucism do not result in pink pupils and therefore most leucistic animals have normally coloured eyes. This is because the melanocytes of the RPE do not derive from the neural crest. Instead, an out-pouching of the neural tube generates the optic cup that, in turn, forms the retina. As these cells are from an independent developmental origin, they are typically unaffected by the genetic cause of leucism.