In 1504, Henry III of Nassau-Dillenburg inherited the County's estates at Breda in the Duchy of Brabant, while his younger brother William became Count of Nassau-Dillenburg in 1516. After the son of Henry III, René of Châlon died in 1544, Count William's eldest son William the Silent became Prince of Orange and Lord of Breda, Stadtholder in the Low Countries from 1559 on. His younger brother, John VI, again reunited all Nassau-Dillenburg possessions in 1561, though the County was again divided after his death in 1606.