In May 2015, Kevin Antreassian, a former member of New Jersey progressive metal band Knife the Glitter and former guitar student of Ben Weinman, became the new rhythm guitarist of the band replacing James Love. In July, Weinman announced during an Australian interview that the band would return to the studio in November to record the follow-up to "One of Us Is the Killer". In the following year, BBC Radio 1 premiered the band's new single "Limerent Death", which would be featured on their sixth studio record "Dissociation". In an interview with "Noisey", Weinman said the Dillinger Escape Plan would stop performing, with Puciato later saying "we're breaking up." Puciato was quoted saying that the band still enjoyed writing, recording and performing together but "we started to reach what felt like a thematic conclusion to our band", comparing the decision to a filmmaker who enjoys the current film he is creating but cannot continue the process indefinitely. Weinman said, "we are going to do the cycle for this album and that's it." "Dissociation" was released on October 14, 2016, through Party Smasher in partnership with Cooking Vinyl. In 2019, the singer acknowledged this album the first part of a trilogy, followed by his 2019 book "Separate the Dawn" (written during their last tour) and finished with The Black Queen record "Infinite Games".