Now in the town of Throop, NY 38 follows the Owasco Outlet through open, mostly flat areas dotted with houses amongst fields and trees. Within Throop, it serves the small hamlet of Sawyers Corners, where NY 38 meets Turnpike Road (County Route 10B or CR 10B). North of this junction, the houses give way to dense forests as the route continues along the waterway into the town of Mentz and the village of Port Byron a short distance north of the town line. It follows Main Street through a mostly commercial and industrial portion of the village to the village center, where it intersects NY 31 at Rochester and Utica Streets. NY 38 turns west, overlapping NY 31 along Rochester Street.