While he was on the Moon, Jameson found the mystical Godstone, an other-dimensional ruby. The jewel grafted itself to his throat (after he made it into a pendant and started wearing it around his neck) and extended tendrils through his body. Moonlight activated the gem, which transformed him into the lycanthropic Man-Wolf, and he fought Spider-Man in this bestial form. The ruby was removed by Spider-Man. Some time after that, the ruby was reattached to Jameson by Morbius the Living Vampire who used the Man-Wolf as a pawn so that Morbius could find a cure for his condition. The Man-Wolf was again defeated by Spider-Man.