The time of the Fifth Dalai Lama, who reigned from 1642 to 1682 and founded the government known as the Ganden Phodrang, was a period of rich cultural development. His reign and that of Desi Sangye Gyatso are noteworthy for the upsurge in literary activity and of cultural and economic life that occurred. The same goes for the great increase in the number of foreign visitors thronging Lhasa during the period as well as for the number of inventions and institutions that are attributed to the 'Great Fifth', as the Tibetans refer to him. The most dynamic and prolific of the early Dalai Lamas, he composed more literary works than all the other Dalai Lamas combined. Writing on a wide variety of subjects he is specially noted for his works on history, classical Indian poetry in Sanskrit and his biographies of notable personalities of his epoch, as well as his own two autobiographies, one spiritual in nature and the other political (see Further Reading). He also taught and travelled extensively, reshaped the politics of Central Asia, unified Tibet, conceived and constructed the Potala Palace and is remembered for establishing systems of national medical care and education.