He played for several clubs in Italy throughout his career, and also had spells in Greece and Hungary with Iraklis Thessaloniki and MFC Sopron respectively. Signori won the Serie A top-scorer award three times and is one of the top ten scorers in Serie A history, although he never received a winners medal in competitive football. At international level, Signori represented Italy 28 times between 1992 and 1995, scoring 7 goals, and took part at the 1994 World Cup, where they reached the final.