In late 1536, the north of England was convulsed in a series of uprisings collectively known as the Pilgrimage of Grace, the most serious opposition to Henry's policies. Cromwell and Cranmer were the primary targets of the protesters' fury. Cromwell and the king worked furiously to quell the rebellion, while Cranmer kept a low profile. After it was clear that Henry's regime was safe, the government took the initiative to remedy the evident inadequacy of the "Ten Articles". The outcome after months of debate was "The Institution of a Christian Man" informally known from the first issue as the Bishops' Book. The book was initially proposed in February 1537 in the first vicegerential synod, ordered by Cromwell, for the whole Church. Cromwell opened the proceedings, but as the synod progressed, Cranmer and Foxe took on the chairmanship and the co-ordination. Foxe did most of the final editing and the book was published in late September.