She considers her role in the show "MariMar" as her biggest break on television. In the series, she played the role of Monica, the arrogant and oppressive yet stupid bestfriend of Angelika. She and Katrina Halili star as the antagonists in the series however Sheena's villain role turned good in the end. She also appeared as Cynthia in "Ako si Kim Sam Soon" and in "LaLola" as the antagonist Vicky. She was also seen in the action show "Zorro". After working on Zorro, her next project was "Rosalinda" wherein she played Becky, Rosalinda's best friend. Halili got her first lead role as Pepper in "SRO Cinemaserye": "Reunion" with Jennica Garcia. She was also reunited with ex-boyfriend Rainier Castillo in Prime time via "Full House".