Nicholson was dining with his friend Edwardes at Peshawar on the evening of 11 May 1857 when news reached them of the beginning of the Indian Mutiny in Delhi. Nicholson and Edwardes immediately planned to form a 'strong movable column' consisting of European and irregular troops which would be able to move and meet any outbreaks in the Punjab. Nicholson's calm response to the outbreak of violence was in no small part due to the distrust he had long held for the Bengal Army, telling his fellow officers; "For years I have watched the army and felt sure they only wanted the opportunity to try their strength with us. Mutiny is like smallpox. It spreads quickly and must be crushed as quickly as possible." Nicholson was awoken on 21 May to the news that the 55th Regiment of Bengal Native Infantry had mutinied at Nowshera. After taking part in the successful disarming of the remaining five regular Bengal regiments at Peshawar, Nicholson accompanied the force dispatched to Nowshera to deal with the 55th. Although the mutineers of the 55th retreated from Nowshera after hearing of the approaching force, Nicholson, upon his grey charger, was able to give chase with his mounted police and cavalry and successfully charged the mutinous sepoys. Nicholson continued to chase down the fleeing sepoys till nightfall, killing over 120 of them and capturing a similar number. Despite initial plans to kill all of the captured mutineers, Nicholson successfully pleaded with his superiors to grant clemency to the Sikh and youngest prisoners. His superiors concurred and executed forty by blowing them from a gun.