St Andrew's is situated on a terrace overlooking the street, its plain red-brick exterior contrasting with the stone buildings on either side. The interior is aisled, with arcaded bays supported by piers rather than the usual columns. The original interior fittings were mostly destroyed during the war, and many of the church's features were procured from other destroyed Wren churches. The weathervane on the steeple comes from St Michael Bassishaw (which was demolished in 1900). A replacement pulpit came from the church of St Matthew, Friday Street. The font and cover also came from here. The royal arms, of the House of Stuart, came from St Olave Old Jewry (demolished, except for its tower, in 1887). There is a figure of St Andrew, dated around 1600, which stands on the north side of the sanctuary and an unusual figure of Saint Anne who is shown holding the Virgin Mary who in turn holds the Christ child. This statue, which is probably north Italian, dates to around 1500.