Dreyfoos founded Photo Electronics Corporation (PEC) in 1963, with George W. Mergens, to address problems in color print reproduction. They developed their groundbreaking Video Color Negative Analyzer (VCNA) in Dreyfoos’ Port Chester, New York basement, then set up a factory in a former church in Connecticut. The VCNA was marketed worldwide by Eastman Kodak Company. Dreyfoos moved PEC to Florida in 1969, and in 1970 a motion-picture version of the VCNA earned an Academy Award from the Academy of Motion Picture Arts and Sciences. From 1990 to 2006, the VCNA was part of the “Information Age: People, Information and Technology” display at the American History Museum of the Smithsonian Institution and remains in its permanent collection. Dreyfoos later invented the innovative LaserColor Printer and assisted his son, Robert Dreyfoos, in developing a digital version of the VCNA for PEC called the Professional Video Analyzing Computer (PVAC).