North of I-75, M-10 forms the border between North Corktown (west) and Midtown Detroit (east). The freeway passes the MotorCity Casino at the interchange with Grand River Avenue. The rest of its route in this part of the city passes through residential zones. Near the interchange with I-94 (Edsel Ford Freeway), M-10 passes the campus of Wayne State University. M-10 intersects I-94 at the first freeway-to-freeway interchange in the United States. North of I-94, the Lodge Freeway is the border between the West Side and New Center. This area is residential on either side of the freeway north of the campus of the Henry Ford Hospital. North of Clairmont Avenue, M-10 curves to the northwest before resuming its north-northwesterly course near Chicago Boulevard. North of Webb Avenue, the freeway follows the western city limits of Highland Park, an enclave within the city of Detroit. M-10 intersects M-8 where it transitions between Davison Avenue and the Davison Freeway on the western edge of Highland Park before the Lodge Freeway curves around to run due west.