Cardinal Seán Brady (leader of the Catholic Church in Ireland) said he was "profoundly sorry and deeply ashamed that children suffered in such awful ways in these institutions. This report makes it clear that great wrong and hurt were caused to some of the most vulnerable children in our society. It documents a shameful catalogue of cruelty: neglect, physical, sexual and emotional abuse, perpetrated against children." He declared that anyone responsible for abusing children in Catholic-run institutions should be held to account. This was echoed by Most Reverend Vincent Nichols (leader of the Catholic Church in England and Wales) "no matter how long ago it happened".