With Chuck back at full health, he takes away whatever luck that Sam and Dean had that prevented them from experiences normal things like a common cold or toothache, as the answer a call from Garth. Garth after saving Sam and Dean tells the boys of a place in Alaska that deals in luck/fortune. Sam discovers that they are dealing with the Goddess Fortuna and after a high stake pool game between the Goddess and Sam, where Sam loses, Dean and Sam's luck is restored as the Goddess Fortuna wants Chuck dealt with.