Over the summer of 2006, Memphis lost their star forward Gasol to a broken foot, leaving Warrick as one of the team's top options as starting power forward. Warrick played in all 82 games in 2006–07, including 43 starts. On December 9, 2006 against the Milwaukee Bucks, Warrick recorded career highs in points (31) and rebounds (13) and made all nine of his free throw attempts in a 100–94 loss. He later set a new career high of 16 rebounds in the Grizzlies 116–111 loss to the Phoenix Suns. Warrick finished the season with averages of 12.7 points per game and 5.1 rebounds per game.