In the early to mid 1960s Francis was represented by the Martha Jackson Gallery in New York City. He returned to California during the 1960s and continued painting, mainly in Los Angeles, but also in Tokyo where he lived primarily in 1973-4. In 1965 Francis started a series of paintings that featured large areas of open canvas, minimal color and strong line. His work evolved further after he began intensive Jungian analysis with Dr. James Kirsch in 1971 and began paying careful attention to his dreams and the unconscious images they suggested.