The redesignated 435th Tactical Airlift Wing had host responsibilities for Rhein-Main AB, beginning July 1975, which included operating the busiest U.S. air terminal in Europe and supporting CONUS-based strategic airlift transiting Rhein-Main. While continuing to function as a tactical and support wing, the 435th TAW gained the mission of aeromedical evacuation in Europe and the Middle East. Provided airlift support for United States European Command (EUCOM) and Headquarters, United States Air Forces in Europe (USAFE), from March 1977 until June 1978.