An issue of "What If?" had asked "What If Spider-Man had Kept his Six Arms?". Morbius is killed by sharks (they were attracted to the blood on Morbius when he landed in the water) before a cure for Spider-Man's mutation is found. After a fight with the Lizard, Spider-Man is advised by Dr. Curt Connors to see Professor X. Spider-Man ends up in a scuffle with X-Men members Angel, Beast, Cyclops and Iceman until Professor X and Jean Grey break it up. Professor X then examines him with Cerebro and learns that Spider-Man's mutation is permanent. Spider-Man then visits Mister Fantastic for a second opinion. Mister Fantastic also states that the mutation is permanent. When the Thing comes in announcing that Doctor Octopus is holding hostages at City Hall demanding to see Spider-Man, Spider-Man easily takes down Doctor Octopus with his six arms. Spider-Man gains enormous popularity and is the nationally recognized spokesperson for the physically challenged, thereby proving J. Jonah Jameson wrong in his assumption that Spider-Man would be considered as a freak. Afterwards, Mister Fantastic summons Spider-Man back to present his latest invention...four arm sheaths that will keep the extra arms invisible (as long as they are worn) when Peter Parker is in his civilian outfit.