In August 2014, it was reported that NBC had purchased a comedy pilot script written and executive produced by Highmore and "Bates Motel" showrunner Kerry Ehrin. In 2015, he appeared in the Libertines' music video for "You're My Waterloo", alongside Marama Corlett. In 2016, Highmore starred in Stephen Poliakoff's BBC Two seven-part miniseries "Close to the Enemy", and Nick Hamm's political comedy-drama film "The Journey". The following year, he began the lead role of Dr. Shaun Murphy in the ABC drama series "The Good Doctor", on which he also serves as a producer. In 2017, he received a nomination for the Golden Globe Award for Best Actor in a Drama Series for his performance.