The Ravens went on and had a big win over the San Francisco 49ers in a week twelve Thursday night thanksgiving game. This was a game where Ravens coach John Harbaugh would face off against his brother Jim Harbaugh who had just taken over as head coach of the 49ers in the 2011 season. The Ravens would go on to end a 49ers win streak in a final score of 16–6. The Ravens recorded a franchise record of nine sacks on 49ers quarterback Alex Smith, three coming from Ravens linebacker Terrell Suggs.