"Karmacode" debuted at number 28 on the "Billboard" 200. Considered by "Billboard" to be "the biggest album in the history of Century Media Records," it was acclaimed by music critics and magazines. Corresponding with the release of the new album, Lacuna Coil toured with Rob Zombie throughout North America in early 2006. After their tour with Zombie, they performed main stage at Ozzfest 2006 along with System of a Down, Ozzy Osbourne, and Hatebreed, becoming the first female-fronted band to co-headline the heavy-metal festival. That summer they also played on the main stage of the Download Festival (a three-day music festival in England's Donington Park), which was headlined by Metallica, Tool, and Guns N' Roses. That December, Lacuna Coil teamed up with In Flames, The Sword and Seemless for a US tour, as well as The Blackest of the Black 2006 Tour.