In 1693 she married the Amsterdam portrait painter Juriaen Pool, with whom she had ten children. Throughout her marriage and adult life she continued to paint and produce commissions for an international circle of patrons. Other women at this time were expected to participate in art forms more traditionally practiced by women, such as sewing and spinning. Ruysch continued working as a painter after she married, mostly likely because her contribution to the family's income allowed them to hire help to care for their children. After her death, despite changing attitudes about flower paintings, Ruysch has maintained a strong reputation.