Payne started a college paper called the "Pastime", which he kept up for several issues. When he was 16, his mother died, and the academy run by his father was failing. Payne, unhappy in his "exile" at Union, left at Easter to be with his family. He told his grieving father that he was dropping out of college to pursue a stage career. On February 24, 1809, he made his debut at the old Park Theatre in New York in the eponymous role of "Young Norval." Scoring a brilliant success, he went on to become the first American actor to play Hamlet; regarded as a prodigy, he was regaled as a home town wonder when he returned to Boston, among other major cities where he toured. His appearances as Romeo to Eliza Poe, Edgar Allan Poe's mother, won particular acclaim, and he favored her to play opposite him in comedies. But despite his success, he had difficulty getting paid by the theaters. In a brief interval away from the theatre, he founded the Athenaeum, a circulating library and reading room.