Next, he married Lou-Anne Gill (with whom he had a second son, Ian Dublin Earle, in January of 1987) and then his fifth wife, Teresa Ensenat, who was an A&R executive for Geffen Records at the time. Earle then married Lou-Anne Gill a second time, and finally, in 2005, married singer-songwriter Allison Moorer with whom he had a son, John Henry Earle, in April 2010. John Henry was diagnosed with autism before age two. In March 2014, Earle announced that he and Moorer had separated.