During the 1788 illness of the King, a conflict arose between the Queen and the Prince of Wales, who were both suspected of desiring to assume the Regency should the illness of the King become permanent, resulting in him being declared unfit to rule. The Queen suspected the Prince of Wales of a plan to have the King declared insane with the assistance of Doctor Warren, and to take over the Regency. The followers of the Prince of Wales, notably Sir Gilbert Ellis, in turn suspected the Queen of a plan to have the King declared sane with the assistance of Doctor Willis and Prime Minister Pitt, so that he could have her appointed Regent should he fall ill again, and then have him declared insane again and assume the Regency. According to Doctor Warren, Doctor Willis had pressed him to declare the King sane on the orders of the Queen.