The Cyclones faced the Lowell Spinners in a series that was dubbed "An MiLB Rematch of 1986", as the Spinners were a Red Sox farm team. The Cyclones took Game 1 in Lowell by a score of 2-1, before dropping game 2 in Brooklyn by a score of 3-1. Game 3 saw the Cyclones take a 2-0 lead in the bottom of the 2nd, but the Spinners tied it up the next half inning. After a solo homer by Marino Campana in the Top of the 7th put Lowell up 3-2, the Cyclones staged a rally to take a 4-3 lead, en route to winning the 2019 New York-Penn League Championship. The Cyclones were managed by former Met Edgardo Alfonzo, whose brother, Edgar, managed the Brooklyn Cyclones in 2001. Other coaches on the team included Pitching Coach Josue Matos, Hitting Coach Delwyn Young and Bench Coach Endy Chavez