Reviews of treatment of excoriation disorder have shown that the following medications may be effective in reducing picking behavior: doxepin, clomipramine, naltrexone, pimozide, and olanzapine. Small studies of fluoxetine, an SSRI, in treating excoriation disorder showed that the drug reduced certain aspects of skin picking compared with a placebo, but full remission was not observed. One small study of patients with excoriation disorder treated with citalopram, another SSRI, showed that those who took the drug significantly reduced their scores on the Yale-Brown Obsessive Compulsive Scale compared with a placebo, but that there was no significant decrease on the visual-analog scale of picking behavior.