Wheeling High School offers over 215 different courses, 22 of which are at the AP level. The academic departments at Wheeling High School are grouped as follows: math/science, career and technology education, English/fine arts, PE/health/dance/drivers' education, foreign language/social studies/ESL/ELL, NJROTC, and special education. The following AP courses are offered at Wheeling High School: Language & Composition, Literature & Composition, Calculus AB, Calculus BC, Statistics, Computer Science, Physics, Chemistry, Biology, Environmental Science, Spanish Language & Culture, Spanish Literature & Culture, French Language & Culture, Italian Language & Culture, Human Geography, World History, United States History, Government & Politics, Psychology, Economics, Studio Art, and Music Theory.