This was the first ride with an Omnimover system. It opened as a free attraction, unlike most, but required a "C" ticket starting in 1972. The original sponsor was Monsanto, which at the time was an agri-chemical company. Irene Kasmer, using Monsanto fabric, designed the uniforms of the attendants. In 1977, Monsanto ended their sponsorship for the attraction. All visual and audio references were removed (except for the end line, "This is Monsanto") and the Monsanto Mighty Microscope's Monsanto logo was replaced with a logo that says "The Mighty Microscope".