US 17 turns north to join SR 143 on six-lane Jefferson Avenue. The two highways intersect SR 152 (Main Street) and SR 306 (Harpersville Road), which continues east as Hampton Roads Center Parkway. US 17 and SR 143 diverge at J. Clyde Morris Boulevard, which heads west as SR 312. The U.S. Highway heads northeast along the six-lane boulevard through a cloverleaf interchange with I-64. US 17 reduces to four lanes as it crosses Brick Kiln Creek into York County, where the highway becomes George Washington Memorial Highway. Within Tabb, the U.S. Highway intersects SR 171 (Victory Boulevard) and meets the northern end of SR 134 (Hampton Highway) at a trumpet interchange. US 17 crosses the Poquoson River just east of its impoundment, Hardwoods Mill Reservoir, then passes through Grafton, where the highway intersects SR 173 (Denbigh Boulevard) and SR 105 (Fort Eustis Boulevard). North of Harris Grove, the U.S. Highway enters Colonial National Historical Park. Within the federal property to the west of Yorktown, US 17 intersects SR 238 and has an interchange with Colonial Parkway. The U.S. Highway crosses the York River on the George P. Coleman Memorial Bridge, a double swing bridge that solicits a toll from motorists heading northbound into Gloucester County.