Despite his medical disqualification for regular military duty, Strauss applied to join the U.S. Navy Reserve in 1925, becoming effective 1926, and he received an officer's commission as a lieutenant intelligence officer. He remained in the reserve as a lieutenant commander. In 1939 and 1940, as World War II began overseas, he volunteered for active duty. He wanted to go into intelligence but was blocked, reportedly because the Director of Naval Intelligence, U.S. Navy was prejudiced against Jews and because Strauss's contributions to B'nai B'rith had aroused suspicion on the part of FBI director J. Edgar Hoover and others in the U.S. intelligence community. Instead, in February 1941, he was called to active duty, and was assigned as a Staff Assistant to the Chief at the Bureau of Ordnance, where he helped organize and manage Navy munitions work. Strauss and his wife moved to Washington, D.C., where they lived in an apartment at the prestigious Shoreham Hotel. She served as an operating room nurse's aide during this period.