At Miami, the wing trained with C-46s under the supervision of the active duty 2585th Air Force Reserve Training Center. The wing was ordered into active service in March 1951 as a result of the Korean War. Along with other reserve units called to active duty, it formed Tactical Air Command's Eighteenth Air Force. The 435th's initial function was to train C-46 aircrews for service in Korea. The wing also trained with Fairchild C-119 Flying Boxcars. Although it remained at Miami, the wing deployed twice while on active duty: to Laurinburg-Maxton Airport, North Carolina from 21 July until 1 September 1951 and to Grenier Air Force Base, New Hampshire from 2 January to 3 March 1952. It was relieved from active duty and inactivated on 1 December 1952 and its mission, personnel and equipment were transferred to the regular 456th Troop Carrier Wing, which was activated the same day.