The O'Connell Superdance is an annual 12-hour dance-a-thon held at the school which raises money for the Cystic Fibrosis Foundation. The Superdance is organized and run by students. It was started under the administration of principal Msgr. James McMurtrie. O'Connell students began holding the Superdance in 1976 because students wanted to speed the discovery of a cure for cystic fibrosis (CF), a fatal disease of the lungs which had claimed the life of sophomore Brenda O'Donnell on April 14, 1975. Her sister Maura was a senior in 1976 and also had cystic fibrosis. Their brother, Sean, died of cystic fibrosis that same year.