Colletti left the Cubs and joined the front office of the San Francisco Giants in 1994 as director of baseball operations. He was promoted to assistant general manager in October 1996. During his tenure, the Giants had an 813–644 overall record (.558), winning an average of 90.3 games per season. He was hired by the Los Angeles Dodgers in 2005. During his tenure with the Dodgers (2005-2014), Colletti had the highest winning percentage of any general manager in the National League.