Subsequently, when marines and Army troops under Major General Roy S. Geiger went ashore on Guam on 22 July under the covering gunfire of Rear Admiral Harry W. Hill's task force, "Zane" worked as an antisubmarine escort vessel, steaming in the vanguard of a reserve transport group, TG 53.19. Significantly, the Guam operation proved to be the last front-line tour for the veteran high-speed minesweeper; for, after remaining in the Marianas until 8 August, she reported to Commander, Service Squadron (ServRon) 10, at Ulithi, in the Carolines, for duty as a target-towing vessel.