During the "Spider-Verse" storyline, Kaine was with the New Warriors in Eastern Europe when they were attacked by Daemos of the Inheritors. A family of Spider-Totem hunters, the Inheritors were tightening their noose on the spiders across the multi-verse, including Kaine, despite him being a clone of Peter Parker and the receptacle of "the Other". After Daemos defeated the New Warriors, Kaine attempted to impale him through the chest with spikes coming from his arm, as "the Other" Spider-monster within was inclined to takeover. Daemos realized that, unlike other spiders, Kaine's arsenal makes him feel pain. As Daemos realizes that Kaine is the current receptacle of the Other, believing he could savour the spider-essence within Kaine for days, he is suddenly by the group of other Spiders including Old Man Spider-Man, Spider-Man of Earth-70105, and Spider-Woman of Earth-65. Kaine is skeptical at first, believing these are clones (Parkers and Stacys) sent by his father, the Jackal. Suddenly, this version of Ben Reilly (the original Scarlet Spider) informs Kaine that they are other versions from across the multi-verse, which surprised Kaine, as his brother Ben Reilly of the 616 Universe was murdered by Green Goblin. Daemos then breaks Spider-Man of Earth-70105's spine and Kaine escapes with the into a portal to Earth-13, which was the Safe Zone.