On February 4, 2012 Brand scored a Sixers career high 33 points in a 100–98 win over the New York Knicks. He finished his first tenure with the Philadelphia 76ers averaging 11 points per game and just over 8 rebounds per game during the 2011–12 season. He averaged 8.6 points and 4.8 rebounds in the 2012 NBA Playoffs in a total of 13 games when the Sixers lost in Game 7 of the Eastern Conference Semifinals to the Boston Celtics 85–75.