The Oroville-Quincy Highway begins in Oroville at Oro-Dam Blvd E just past Olive Highway and runs east. It continues east roughly paralleling Olive Highway until it merges with SR 162 just before Oakvale Ave. It breaks off from SR 162 at Wally B Lane running parallel to the highway for a mile or so before reconnecting at Kelly Ridge Road. The highway runs roughly north and crosses Lake Oroville over the Bidwell Bar Bridge. SR 162 ends near here at Foreman Creek Road, but the Oroville-Quincy Highway continues toward Berry Creek and Madrone Lake. Here it turns east again and runs to Brush Creek. From Brush Creek, the highway turns north for to Palmetto. Here the highway turns ENE to Buck's Lodge and Bucks Lake. It then goes east along Bucks Lake Road past Meadow Valley and Spanish Ranch before arriving at Quincy, a total distance of .