Vajramuni began his career as a stage actor and gained popularity with his portrayal of Ravana in Kanagal Prabhakar Shastri's play "Prachanda Ravana". He made his film debut in 1969 with Puttanna Kanagal's "Mallammana Pavada". His pairing with Rajkumar, with the latter as the lead, in the 1970s came to be widely appreciated, with films such as "Sipayi Ramu" (1972), "Sampathige Savaal" (1974), "Premada Kanike" (1976), "Bahaddur Gandu" (1976), "Giri Kanye" (1977) and "Shankar Guru" (1978). Recognizing his contribution to Kannada cinema, he was awarded the Lifetime Contribution to Kannada Cinema Award in 2006.