Five days later on the August 20 episode of "SmackDown", Mysterio lost to the debuting Alberto Del Rio by submission. Del Rio, however, continued his attack after the match, sidelining Mysterio for a month, in which time Del Rio would taunt him. The following week a feud was sparked between the two, when Del Rio attacked Mysterio and broke his wrist following a match with Kane. On the October 8 episode of "SmackDown", Mysterio defeated Del Rio, and thus ending his undefeated streak. At Bragging Rights, Mysterio represented Team SmackDown, and despite being attacked by teammate Del Rio, he and Edge managed to defeat the rest of Team Raw, giving Team SmackDown the victory. At Survivor Series, Mysterio led a team to victory over Team Del Rio, and at , both were part of a fatal four-way Tables, Ladders, and Chairs match for the World Heavyweight Championship, won by Edge. His feud with Del Rio culminated on the January 7, 2011, episode of "SmackDown" in a two out of three falls match, which Del Rio won by countout.