By June 1926, Weber was signed to direct "Sensation Seekers", a romantic drama based on Ernest Pascal's novel "Egypt", that also starred Billie Dove. However, just before her wedding, Weber replaced Pollard as director of "Uncle Tom's Cabin", as he had been hospitalized in Manhattan with blood poisoning and a shattered jaw caused by the "maltreatment" of a tooth infection by a New York dentist. Weber ceased work on "Sensation Seekers" and was willing to interrupt her honeymoon to travel to Louisiana to direct the location scenes for "Uncle Tom's Cabin".