Toxic additives used in the manufacture of plastic materials can out into their surroundings when exposed to water. Waterborne hydrophobic pollutants collect and magnify on the surface of plastic debris, thus making plastic far more deadly in the ocean than it would be on land. Hydrophobic contaminants are also known to bioaccumulate in fatty tissues, biomagnifying up the food chain and putting pressure on apex predators. Some plastic additives are known to disrupt the endocrine system when consumed, others can suppress the immune system or decrease reproductive rates.