The Roselle Park High School Panthers compete in the Union County Interscholastic Athletic Conference, which is comprised of public and private high schools in Union County and was established after a reorganization of sports leagues in Northern New Jersey by the New Jersey State Interscholastic Athletic Association (NJSIAA). Prior to the NJSIAA's 2009 realignment, the school had participated in the Mountain Valley Conference, which included public and private high schools in Essex County, Somerset County and Union County. With 434 students in grades 10-12, the school was classified by the NJSIAA for the 2019–20 school year as Group I for most athletic competition purposes, which included schools with an enrollment of 75 to 476 students in that grade range. The school was classified by the NJSIAA as Group I North for football for 2018–2020. The school's Athletic Director is James Foy.