He graduated Ph.D. from Erlangen University in 1814, publishing as his thesis a critical catalogue of plants in the university's botanical garden. After that he continued to devote himself to botanical study, and in 1817 he and Johann Baptist von Spix were sent to Brazil by Maximilian I Joseph, the king of Bavaria. They travelled from Rio de Janeiro through several of the southern and eastern provinces of Brazil and travelled up the Amazon River to Tabatinga, as well as exploring some of its larger tributaries.