Estuaries tend to be naturally eutrophic because land-derived nutrients are concentrated where runoff enters the marine environment in a confined channel. The World Resources Institute has identified 375 hypoxic coastal zones around the world, concentrated in coastal areas in Western Europe, the Eastern and Southern coasts of the US, and East Asia, particularly in Japan. In the ocean, there are frequent red tide algae blooms that kill fish and marine mammals and cause respiratory problems in humans and some domestic animals when the blooms reach close to shore.