Moore entered Bryn Mawr College in 1905. She was graduated four years later with an A.B., having majored in history, economics, and political science. The poet H.D. was among her classmates during their freshman year. At Bryn Mawr, Moore started writing short stories and poems for "Tipyn O'Bob", the campus literary magazine, and decided to become a writer. After graduation, she worked briefly at Melvil Dewey's Lake Placid Club, then taught business subjects at the Carlisle Indian Industrial School from 1911 to 1914.