"Men in Trees" was among several scripted series affected by the 2007-08 Writers Guild of America strike. In particular, 14 new episodes were written for the second season, versus an order for 22. Combined with five episodes carried over from the first production season, "Men in Trees" had 19 completed episodes for its second broadcast season in the United States and was on hiatus from late December 2007 until it returned on February 27, 2008, taking over for "Cashmere Mafia". The series was not aired during the May 2008 sweeps period. On May 4, 2008, ABC announced the official cancellation of the show and said that the final episodes would be broadcast starting on May 28, 2008.