Tadhg Beirne made his debut for Munster in the provinces 25–10 defeat away to Glasgow Warriors on 7 September 2018. Munster's 64–7 win against Ulster on 29 September 2018 was a record win for the province in the Pro14; Munster's previous record win being 47–0 against Zebre in 2016. In round one of the 2018–19 Champions Cup on 13 October 2018, a try from Stander and five points from the boot of Joey Carbery secured a 10–10 draw in Sandy Park against Exeter Chiefs, in a match in which Dan Goggin and Neil Cronin made their competitive European debuts, whilst Tadhg Beirne, who was Man-of-the-Match, Mike Haley and Joey Carbery made their European debuts for Munster. One week later, tries from Mike Haley, Rhys Marshall, Joey Carbery, who also kicked four conversions and one penalty in a Man-of-the-Match performance, Sammy Arnold and Andrew Conway helped Munster to a 36–22 bonus-point victory at home against Gloucester.