As Minister for International Trade, he promoted free trade and always characterized the North American Free Trade Agreement (NAFTA) as "a tremendous success". and a model to expand upon. He was a key participant in the World Trade Organization (WTO) trade talks, claiming that Canada's main goal of lowering agricultural subsidies would be of great benefit to the world's poorer nations. At the 2003 WTO Ministerial Conference in Cancún, Pettigrew played an aggressive role as chair of the working group on the Singapore issues, controversial sectors of proposed liberalization which were bitterly opposed by some developing nation delegates, not to mention masses of protesters outside of the gates where the meetings were held. He also championed the Free Trade Area of the Americas (FTAA), and in the period leading up to the Summit of the Americas in Quebec City in 2001, he spearheaded a campaign to allay growing public suspicion of the deal by promising the eventual release of the draft negotiating texts. After a delay due to translating the texts into the Portuguese language, the texts were made publicly available July 3, 2001. Throughout his mandate at International Trade, he was heavily embroiled in the US - Canada softwood lumber dispute.