Nothing is known about Saint-Georges's early musical training. Given his prodigious technique as an adult, Saint-Georges must have practiced the violin seriously as a child. There has been no documentation found of him as a musician before 1764, when violinist Antonio Lolli composed two concertos, Op. 2, for him, and 1766, when composer François-Joseph Gossec dedicated a set of six string trios, Op. 9, to Saint Georges. Lolli may have worked with Bologne on his violin technique and Gossec on compositions.