New York State Route 52 Business (abbreviated NY 52 Bus.) is a business route of NY 52 that extends for through the city of Beacon in Dutchess County. The route is signed as east–west, starting at I-84 / NY 52 exit 41 and NY 9D north of Beacon and ending at I-84 / NY 52 exit 44 southwest of the village of Fishkill, where NY 52 leaves I-84, ending the I-84 / NY 52 concurrency. NY 52 Business is not posted on guide signs on I-84.