The city recovered after 1800, re-establishing its role as the transportation hub for the New England region with its network of railroads, and even more importantly, the intellectual, educational and medical center of the nation. Along with New York, Boston was the financial center of the United States in the 19th century, and was especially important in funding railroads nationwide. In the Civil War era, it was the base for many anti-slavery activities. In the 19th century the city was dominated by an elite known as the Boston Brahmins. They faced the political challenge coming from Catholic immigrants. The Irish Catholics, typified by the Kennedy Family, took political control of the city by 1900.