In 1306, Agnes was recalled to head the monastery in Montepulciano. Agnes reached a high degree of contemplative prayer and is said to have been favoured with many visions. After her return, she proceeded to build a church, Santa Maria Novella in Florence, to honour the Blessed Mother, as she felt she had been commanded to do in a mystical vision several years earlier. She also had a vision of Dominic Guzman, under the inspiration of which she led the nuns of her monastery to embrace the Rule of St. Augustine as members of the Dominican Order. She was frequently called upon to bring peace to the warring families of the city.