Students are encouraged to take up extracurricular activities, with the help of the Karnatak Science College Gymkhana. The Gymkhana has various departments, for example, Sports Department – including Cricket, Volleyball, Basketball, Hockey, Indian Games, Tennis, football, Badminton & indoor games among others – Cultural & Youth Festival Department, the Miscellany Department which brings out the college magazine "Varnasaptaka" annually, the Debate & Wall paper department, and the Reading Room department. The college has a Science Association, in addition to Study Circles in different departments.