Vecna was #4 on "CBR"'s 2020 "10 Unique (& Powerful) Villains To Spice Up A High Level Dungeons & Dragons Campaign" list — the article states that "Once a humble necromancer, he rose all the way to becoming a lich and finally a god through an act of ascension. Resplendent with evil this figure is a god whos domain encompasses the undead and secrets. This villain is the apex of the living dead. A campaign centered around fighting the undead in any established D&D setting could use him as the big bad at the end. He currently doesn't have a stat block in 5e but some homebrew stats exist for him".