Pilottown was constructed and settled after September 1860 in its current location. It replaced the earlier village of La Balize, that had been founded more than 160 years earlier downriver. After the hurricane of September 14–15, 1860, blew its buildings down and destroyed the area in a storm surge, La Balize was finally abandoned. The main river passage was moved to the Southwest Pass, because of its deeper water. The Mississippi River pilots built their new settlement upriver above Head of Passes. They named it Pilottown.