In addition to overharvesting, it has also been negatively affected by pollution and loss of migratory waterways. It is vulnerable to population declines through overfishing due to its extremely slow reproductive cycle; most individuals caught before 20 years of age have never bred and females spawn only once every four or five years. The specific harvesting of breeding females for their roe is also damaging to population size. Few individuals ever reach the extreme old age or large size that those of previous generations often did.