New York State Route 263 (NY 263) is a state highway located entirely within the town of Amherst in Erie County, New York, in the United States. It extends from just north of the northeast corner of the city of Buffalo in a roughly northeast direction almost straight to just south of the north county line. The road is named Millersport Highway north of Eggert Road in Amherst for the community at its northern terminus. The section between its southern terminus at U.S. Route 62 (US 62) and the Eggert Road intersection is named Grover Cleveland Highway.