"Graph's" second war patrol was from 19 November 1942 to 8 December 1942, also in the Bay of Biscay. During the patrol, she was ordered to intercept the Italian cargo ship "Cortellazzo", which was passing through the area "en route" from Bordeaux to Japan with a cargo of 2000 tons of machinery. However, "Graph" failed to find the ship and the patrol was without incident. "Cortellazzo" was sunk within days by HMS "Redoubt", one of the destroyer escorts of an Allied troop convoy, after "Redoubt" had ordered "Cortellazzo" crew to abandon ship and had picked them up.