PA 467 begins at an intersection with PA 187 (Rome Road) in the hamlet of Myersburg in Rome Township. The route progresses eastward on a bridge built in 1962 over Wysox Creek and enters a stretch of residences in Rome Township. After the intersections with State Route 1023 (SR 1023, Johnson Hill Road) and Joyce Road, PA 467 turns to the northeast and becomes more rural. After the intersection with Harmony Hill Road, the highway enters the hamlet of Allis Hollow. After the intersection with Ridge Road, PA 467 leaves the small community and makes a southeastern turn into Orwell Township. There, the highway intersects with SR 1010 (Otis Hill Road), where PA 467 bends to the northeast. In Orwell Township, PA 467 turns eastward after crossing Johnson's Creek. The highway passes numerous residences before turning northeastward into the hamlet of Zion Heights and soon Wells Hollow.