In the third game of the season against Maryland, Slaton and the Mountaineers beat the Terps 31–14. Slaton finished the game with 26 carries for 137 yards and three touchdowns, including Slaton's longest run which was a 22-yard touchdown. Slaton earned the Wrangler Player of the Game honors presented by ESPN. In the following game against ECU, Slaton tied the school record scoring his 42nd rushing touchdown of his career and finished the game with 18 carries for 110 yards and a touchdown along with three receptions for 42 yards as the Mountaineers won 48-7. In the 5th game of the season, Slaton, for the 3rd year in a row, was held under 100 yards rushing by South Florida - finishing the game with just 55 yards on 13 carries as WVU suffered their first loss of the season. Against Syracuse, Slaton had 69 yards on 15 carries and 51 yards on four receptions in the 55–14 win. The following game against Mississippi State, which was homecoming for the Mountaineers, Slaton rushed for 127 yards on 23 carries for one touchdown in the 38-13 win. Slaton's touchdown put him in the record books as the school's all-time leading scorer on the ground, passing Ira Rodgers and Avon Cobourne with 43 rushing touchdowns.