Since 1996 Méndez has run a private practice with her writer husband Adam Eeuwens. Rebeca Méndez Design specializes in work with cultural and socially-oriented clients, designing books on Bill Viola for the Whitney Museum and the Deutsche Guggenheim; books with curator Alma Ruiz for MoCA ; projects with architects such as Thom Mayne/Morphosis, Frank Gehry and Greg Lynn; with the Swedish activist documentary maker Fredrik Gertten and with Danish director Pernille Rose Grønkjær; with director Mike Figgis; visionary Bob Stein; author Ashton Applewhite; design theorist Benjamin H. Bratton, photographer Iwan Baan and musician Ben Frost, among others.