He left the Franciscans for the Lutheran Church in order to accept an appointment at the Reformed Church-dominated University of Basel in 1529. He had long harboured an interest in the Lutherans, and during the German Peasants' War, as a monk, he had been repeatedly attacked. A professor of Hebrew, and a disciple of Elias Levita, he edited the Hebrew Bible (2 vols. fol., Basel, 1534–1535), accompanied by a Latin translation and a large number of annotations. He was the first German to produce an edition of the Hebrew Bible.