In 2016, Justin Chang of the "Los Angeles Times" ranked the film as De Palma's most underrated of the 1970s, writing that "for all its low-budget creakiness, feels fully formed—from its sly opening bit of misdirection to its adroit use of split-screen to its memorably churning Bernard Herrmann score. De Palma's choice of subject matter couldn't have been more appropriate: With this film he effectively conjoined himself to Hitchcock, announcing himself as a skillful mimic with a mischievous side all his own." "Sisters" currently has 87% on the review aggregator Rotten Tomatoes with the site's consensus reads, "Clever yet clearly indebted to the masters of the genre, "Sisters" offers an early glimpse of DePalma at his stylishly crafty peak".