Natsume was the voice of a character in the Sega video game "Ryu Ga Gotoku 2" (龍が如く2) or "Yakuza 2" for PlayStation 2 released on December 7, 2006. Her role as a nightclub hostess in the game was minor but she played a large part in publicity for the game. She was also engaged to publicize the August 2008 Nintendo DS supernatural ghost story game "You Mustn't Look" (Mitewa Ikenai - みてはいけない) from video game producer Dimple. Part of the campaign was a comic photo series and video at the offices of game reporters Famitsu.