The Midland Park High School Panthers participate in the Patriot Division of the North Jersey Interscholastic Conference, which is comprised of small-enrollment schools in Bergen, Hudson, Morris and Passaic counties, and was created following a reorganization of sports leagues in Northern New Jersey by the New Jersey State Interscholastic Athletic Association (NJSIAA). With 227 students in grades 10-12, the school was classified by the NJSIAA for the 2019–20 school year as Group I for most athletic competition purposes, which included schools with an enrollment of 75 to 476 students in that grade range. Prior to the realignment that took effect in the fall of 2010, Midland Park was a member of the smaller Bergen-Passaic Scholastic League (BPSL). The school's co-op football program was classified by the NJSIAA as Group II North for football for 2018–2020.