Keilar began her on-air career in Yakima, Washington, at the CBS affiliate KIMA. She also co-hosted the morning drivetime show "Billy, Blue and Brianna, too: The Morning Zoo" on contemporary hits station, KFFM. She then moved to CBS News, where she served as an anchor, reporter and producer for a CBS newscast that aired on MTVU, MTV's college network. She was also a fill-in anchor on the CBS News overnight newscast, "Up to the Minute", and a freelance reporter for the weekend edition of "CBS Evening News".