West delivered a performance of the song in Hyde Park when headlining the second and final day of the 2009 Wireless Festival. On August 6, 2009, he performed it for Casio G-Shock's the World event at Cipriani's on Wall Street, performing in front of a shifting digital display screen that counted down the time West was onstage. At the 2011 Coachella Festival, West transitioned from his single "Jesus Walks" (2004) into a performance of the song. West's dancers left the stage during the transition and for the performance, he remained at the front of the stage throughout. West headlined the 2015 Glastonbury Festival, with his set including a performance of the song. As part of West and his gospel group the Sunday Service Choir's tribute to deceased basketball player Kobe Bryant at the Super Bowl LIV in 2020, they performed the song. West and the Sunday Service Choir performed a gospel version of "Can't Tell Me Nothing" at the Credit Union 1 Arena in Chicago on February 16, 2020.