Pennsylvania Route 446 (PA 446) is an state highway located in McKean County, Pennsylvania. The southern terminus is at Route 46 in the Keating Township neighborhood of Farmers Valley. The northern terminus is at the New York state line near Portville, New York. Route 446 is mountainous for most of its length and its only street designation is Main Street. PA 446 is part of a family of routes interconnected with PA 46. However, unlike several others, PA 446 does connect to its parent route and PA 346.