In the autumn of that year, on the advice of her father, Venerini entered the Dominican Monastery of St. Catherine, where her aunt was a member of the monastery. She remained in the monastery for only a few months, however, because the sudden death of her father forced her to return to care for her mother. Her brother, Domenico, then died at 27. A few months later, worn out by grief, her mother also died. In the meantime, Rose's sister Maria Maddalena married. There remained at home only Orazio and Rosa, by now 24 years old. Rosa began to gather girls and women of the area in her own home to recite the rosary.