In 1768 he built the famous anatomy theatre and museum in Great Windmill Street, Soho, where the best British anatomists and surgeons of the period were trained. His greatest work was "Anatomia uteri umani gravidi" anatomy of the human gravid uterus exhibited in figures (1774), with plates engraved by Rymsdyk (1730–90), and published by the Baskerville Press. He chose as a model for clear, precise but schematic illustration of anatomic dissections the drawings by Leonardo da Vinci conserved in the Royal Collection at Windsor: Kenneth Clark considered him responsible for the Eighteenth-century rediscovery of Leonardo's drawings in England. He praised them highly in his lectures and planned to publish them with his own commentary, but never had the time for the project before his death.