Lukes attended the Royal Grammar School in Newcastle upon Tyne, completing his studies there in 1958. Lukes completed his BA in 1962 at Balliol College, Oxford. He worked as a research fellow at Nuffield College and as a lecturer in politics at Worcester College and completed his MA in 1967. In 1968, he completed his doctorate on the work of Émile Durkheim. From 1966 to 1987 he was fellow and tutor in politics at Balliol College. He is a Fellow of the British Academy (FBA) and a visiting professor at the University of Paris, New York University, University of California, San Diego, and Hebrew University.