Otis Norcross, Jr. and Lucy Ann's eight children include: their first four children, all of whom died in infancy: two sons (the first originally named Otis, and two daughters. Those surviving into maturity included: Laura [Norcross (1845–1926), married Kingsmill Marrs; Otis Norcross "Esq" (b. 1848) (Harvard College, A.B., 1870, Harvard Law, LL.B., 1873), married Susannah Ruggles [Plympton; descendant of Timothy Ruggles; Addison Norcross (1850–1873; "a". 23 yrs.); and Grenville Howland Norcross, "Esq" (1854–1937) (Harvard College, A.B., 1875, Harvard Law, LL.B., 1877), who resided as a bachelor at the family home; No. 9 Commonwealth Avenue, as was customary for the time.