The mistake remained undetected even during manufacture of the sweets by James Appleton, an "experienced sweetmaker" employed by Neal, though Appleton did observe that the finished product looked different from the usual humbugs. Appleton was suffering symptoms of illness during the sweet-making process and was ill for several days afterwards with vomiting and pain in his hands and arms, but did not realise it was caused by poison. of lozenges were sold to Hardaker who also noticed the sweets looked unusual and used this to obtain a discount from Neal. Like Appleton, Hardaker, as one of the first to taste the sweets, also promptly became ill.