NY 281 continues north through Homer, passing a stretch of residences before an intersection with CR 102 (Cold Brook Road). Passing west of Lower Little York Lake, NY 281 enters the hamlet of Pratts Corners, where it becomes a two-lane residential street, intersecting with CR 109 (Little York Crossing Road). After CR 109, the route runs west of Upper Little York Lake, passing multiple homes and fields near the lakeside before intersecting with CR 109A (Little York Lake Road). After several blocks of paralleling, CR 109A bends back and terminates at NY 281 to the north. At that point, the route crosses into the town of Preble.