The striped skunk is polygamous, and normally breeds once a year, though yearling females who have failed to mate may enter a second estrous cycle a month after the first. The mating season usually occurs between mid-February to mid-April, though it is delayed at higher latitudes. Prior to copulating, the males' testicles swell during the January–February period, with maximum size being attained in March. Males during this period will cover much ground in their search for females, sometimes covering per night.