Bacsinszky withdrew from the Shenzhen Open and the Apia International Sydney due to injury. With no warm-up match before the Australian Open, she matched her best result at this tournament with a third-round appearance, losing to Daria Gavrilova in three sets. Entering the Fed Cup as the Swiss No. 1, Bacsinszky won both of her rubbers against French player Alizé Cornet and Kristina Mladenovic. With injuries carried on from the Fed Cup, she had to retire in the first round of Doha and eventually withdrew from Dubai, the first Premier-5 event of the year. The Swiss, however, reached the second week of Indian Wells for the third consecutive year, only to retire against Karolína Plíšková due to wrist injury. She also had to withdraw from the Miami Open, where she was a semifinalist from the previous year. In the Fed Cup semifinal against Belarus, Bacsinszky beat Aryna Sabalenka but lost to Aliaksandra Sasnovich, and Switzerland eventually lost to Belarus 2-3 in that round.