GTRI's research spans a variety of disciplines, including national defense, homeland security, public health, education, mobile and wireless technologies, and economic development. Major customers for GTRI research include United States Department of Defense agencies, the state of Georgia, non-defense federal agencies, and private industry. Overall, contracts and grants from Department of Defense agencies account for approximately 84% of GTRI's total research funding. Since it was established, GTRI has expanded its engineering focus to include science, economics, policy, and other areas that leverage GTRI's partnership with Georgia Tech. GTRI researchers are named on 76 active patents and 43 pending patents.