Deleuze and Guattari analyse the relationship of desire to reality through the mental productivity of schizophrenia and psychosis, and the social transformations that capitalism has brought forward; both are intensely influencing consequences of each other's vast effects. They write about psychology, economics, society, the creative arts, literature, civilization, psychiatry, anthropology and history in engagement with this idea. They outline a "materialist psychiatry" modeled on the unconscious in its relationship with its productive processes, built on the concept of desiring-production (which interrelates "desiring-machines" and "bodies without organs"), offer a critique of Sigmund Freud's psychoanalysis that especially focuses on the Oedipus complex, and repurpose Karl Marx's materialist account of the history of society's modes of production as a development through "primitive, despotic and capitalist" societies that has increased social conditions that can be likened to schizophrenia. Friedrich Nietzsche's ideas of the will to power and eternal recurrence also have integral roles in how Deleuze and Guattari describe schizophrenia as vast and unbound as opposed to something linear and set in place, propelling its subjects towards unpredictable and revolutionary behavior; the book extends from much of Deleuze's work in "Difference and Repetition" (1968) which similarly details being as vast and unbound. They also detail their different organisations of production, the act of "inscription" (an act inflicted on all social bodies which corresponds with the socially influencing effects of Marx's "distribution" and "exchange"), and they develop a critical practice that they called schizoanalysis which the book proposes.