Barrie made her screen debut in the comedy film "Operation Bullshine" in 1959 leading to roles in popular films including "What a Whopper" and "Doctor in Distress". Barrie then starred in two of the Carry On films, a long-running series of British comedy films: she had a supporting turn as a cab driver in "Carry On Cabby" (1963) and took the title role in "Carry On Cleo" (1964). In 1965, Barrie starred alongside Billy Fury in his film "I've Gotta Horse".