During the second surgery in April 1898, Bossi probably "did not attempt a hysterectomy but merely excised the tumour in a myomectomy". Shortly after the surgery Constance developed uncontrollable vomiting which led to dehydration and death. The immediate cause of death is thought to have been severe paralytic ileus, which developed either as a result of the surgery itself or of intra-abdominal sepsis. Constance is buried in Genoa (Italy), in the Monumental Cemetery of Staglieno. A memorial statue depicting a nude pregnant Constance is included in the Oscar Wilde Memorial Sculpture in Merrion Square in Dublin.