Longfin mako sharks are predators that feed on small schooling bony fishes and cephalopods. Whether this shark is capable of elevating its body temperature above that of the surrounding water like the other members of its family is uncertain, though it possesses the requisite physiological adaptations. Reproduction in this species is aplacental viviparous, meaning the embryos hatch from eggs inside the uterus. In the later stages of development, the unborn young are fed nonviable eggs by the mother (oophagy). The litter size is typically two, but may be as many as eight. The longfin mako is of limited commercial value, as its meat and fins are of lower quality than those of other pelagic sharks; however, it is caught unintentionally in low numbers across its range. The International Union for Conservation of Nature has assessed this species as endangered due to its rarity, low reproductive rate, and continuing bycatch mortality. In 2019, alongside the shortfin mako, the IUCN listed the longfin mako as "Endangered".