Throughout 2011 and 2012 Golightly worked on a Marcus Nispel horror film titled "Backmask", which was later retitled "Exeter". Golightly also worked on "Gone Missing" for the Lifetime network, playing the role of Matty. In June 2014, Golightly was cast as a series regular in an Amazon Studios comedy pilot "Red Oaks", in which she played the role of Karen. The series began filming their first season in late May 2015. In 2016, Golightly appeared as Karen in the remake of Eli Roth's horror film, "Cabin Fever". In May 2016, Golightly was cast as Libby in the dance-comedy film "Step Sisters".