The Browns relocated to Baltimore for the 1954 season, becoming the Baltimore Orioles. In 1954, Larsen went 3–21 with a 4.37 earned run average and 80 strikeouts in 29 games. He led the major leagues in losses and finished third in the league in earned runs allowed (98). The Orioles won only 54 games that season, while having 100 losses, and finished the season in seventh place. Two of Larsen's three wins were against the New York Yankees, including a 10–0 shutout on July 30, his last win of the season. His other victory was against the Chicago White Sox on May 30.