He taught at Lehigh University, which established the Donald T. Campbell Social Science Research Prizes. Prior to that he was on the faculty of Maxwell School of Syracuse University, 1979–1982, and Northwestern University from 1953 to 1979. He gave the William James Lecture at Harvard University in 1977. In June 1981, working with Alexander Rosenberg, Campbell organized an international conference held at Cazanovia, New York, to formulate the program of what he called an "Epistemologically Relevant Sociology of Science" (ERRES). By Campbell's own account, this project was at least premature.