From 1571 onwards, Walsingham complained of ill health and often retired to his country estate for periods of recuperation. He complained of "sundry carnosities", pains in his head, stomach and back, and difficulty in passing urine. Suggested diagnoses include cancer, kidney stones, urinary infection, and diabetes. He died on 6 April 1590, at his house in Seething Lane. Historian William Camden wrote that Walsingham died from "a carnosity growing "intra testium tunicas" cancer". He was buried privately in a simple ceremony at 10 pm on the following day, beside his son-in-law, in Old St Paul's Cathedral. The grave and monument were destroyed in the Great Fire of London in 1666. His name appears on a modern monument in the crypt listing the important graves lost.