Principal photography for "Tenacious D in The Pick of Destiny" commenced in the spring of 2005, with the production finishing later that summer. The film held its first test screening to the press in October 2005. The film held two re-shoots in the summer of 2006 and according to Lynch, every crew member from the principal photography came back because they "had such a fun time working on set". Black also stated that the filming on this production was "the most fun I've ever had filming a movie".