Astra qualified directly in the third qualifying round after winning the Romanian Cup and met Slovan Liberec, winning both legs 3–0 in Giurgiu and 3–2 in Liberec, this time being the first European match to take place in Giurgiu. In the play-off round, Astra met Olympique Lyonnais, defeating them away in Lyon in a 2–1 win, with Kehinde Fatai and Constantin Budescu scoring the goals of victory. In Giurgiu, Lyon won 1–0 but Astra Giurgiu went on to the group stage phase due to the away goals rule. They were subsequently drawn in Group D alongside Red Bull Salzburg, Celtic and Dinamo Zagreb. Astra began their group stage adventure with a harmful 1–5 defeat at Stadion Maksimir in Zagreb against Croatian champions Dinamo, ending with Aurelian Chițu scoring their first goal in the group stages of a European cup. On 2 October 2014, Astra played Red Bull Salzburg one of the most important matches held on Marin Anastasovici Stadium in Giurgiu. Astra took the 1–0 lead with Takayuki Seto's goal, but were stunned by Jonatan Soriano's winner, losing 1–2. On matchday 3, Astra faced Celtic at Glasgow in a match which ended 1–2. On matchday 4, Astra hold Celtic in a 1–1 draw at Giurgiu, with William Amorim scoring the equaliser that brought their first group stage point. On matchday 5, Astra won 1–0 against Dinamo Zagreb with Sadat Bukari's winner, and secured its first ever victory in the Europa League group stages. Astra's Europa League campaign concluded at Red Bull Arena in Salzburg with another heavy 1–5 defeat to Red Bull. Astra ended in fourth place with four points, behind Salzburg (16 points), Celtic (8) and Dinamo (6).