In 1854, her uncle Kamehameha III died and her brother Alexander Liholiho succeeded him as King Kamehameha IV. According to Robert Crichton Wyllie, the Minister of Foreign Affairs and a trusted friend of the royal family, opponents of the new king were planning to overthrow him and place his sister Princess Victoria on the throne instead. However, the conspiracy never culminated in anything. She became "Kuhina Nui" in 1855 mainly due to her brother's ascension to the throne after the death of her uncle. It is probable that Kamehameha III had meant for Keoni Ana to hold the office until his death; Keoni Ana did retain the role of Minister of the Interior. Victoria presided over the King's Privy Council.