A sub-plot in "Salvation's Reach" follows Doc Dorden's battle against terminal cancer, and his determination to serve the Tanith First until the very end. Another sub-plot explores the relationship between Captain Ban Daur and his new partner, Elodie. Through the latter, readers are granted an insight into the lives of the wives and other civilians that follow Imperial Guard regiments around the galaxy. The novel also features the appearance of Brother Kater Holofurnace of the Iron Snakes, a Chapter of Space Marines that previously appeared in Abnett's novel, "Brotherhood of the Snake".