According to Miller, the colonists split up, with a small group relocating to Croatoan while the main body sought shelter with the Chowanoke. However, the colonists would quickly spread European diseases among their hosts, decimating the Chowanoke and thereby destabilising the balance of power in the region. From there Miller reasoned that the Chowanoke were attacked, with the survivors taken captive, by the "Mandoag", a powerful nation to the west that the Jamestown colonists only knew from the vague accounts of their neighbours. She concluded that the Mandoag were the Eno, who traded the remaining Lost Colonists as slaves until they were dispersed throughout the region.