"The Times Literary Supplement" in its review, written by Philip John Stead, of 19 November 1954, was enthusiastic when it asked, "Where do scientists go when they vanish from the ken of the Security Services? A solution to this fascinating problem is propounded in "Destination Unknown". While it must be admitted that the secret, when disclosed, smacks rather of "The Thousand and One Nights" than of modern international rivalry for scientific talents, it may surely be excused on the ground that it provides Mrs. Christie with a story-tellers holiday from the rigours of detective fiction. Readers may regret the absence of the tonic logicalities of crime's unravelling – though "clues" are not altogether missing – for the secret service story belongs largely to Adventure, but in their place is the author's obvious pleasure in the wider horizons of the more romantic genre." The review concluded, "However much the purist yearns for Poirot or Miss Marple, he can hardly deplore Mrs. Christie's bright, busy excursion into this topical and extravagant sphere."