"Mega Man Xtreme 2" ranked number six on Japanese sales charts for its release week, selling 17,110 units. According to Dengeki Online, the game sold 88,564 units in Japan during 2001, making it the 127th best-selling game in the region for that year. In 2012, IGN listed both "Mega Man Xtreme" games among titles they wished to see downloadable from the Nintendo eShop for Nintendo 3DS. On July 18, 2013, it was confirmed that "Mega Man Xtreme 2" is planned for release on the 3DS Virtual Console, which released in Japan on December 25, 2013 and on May 29, 2014 in North America.