Kaine is next seen being hunted by Ana Kravinoff and Alyosha Kravinoff. Their next attempt to hunt Kaine succeeds in brutally beating him; he barely escapes with his life, the Kravinoffs mocking that he will be "The only spider left. Even if you are an ugly one". Kaine manages to get to Peter's apartment to warn Peter that they, the "spiders", are being hunted before he falls unconscious. Later that night, after shaving his beard and cutting his hair, Kaine aids Spider-Man, Arachne, and Anya Corazon against the Kraven clan. After the Kravens abduct Araña and Arachne, Kaine tells Peter to 'run. Run and screw the rest'. Disgusted at Kaine's selfishness even when the two of them share DNA and memory, Spider-Man bluntly informs Kaine that the difference between them is the fact that he doesn't use his life's misery as an excuse to give up the good fight. After Spider-Man is lying, defeated, in an open grave with the Kravens advancing, Kaine knocks him unconscious, puts on his costume, and fights the Kravens in his place. He is mauled, stabbed, and ultimately sacrificed to bring Kraven the Hunter back from the dead, thus achieving redemption with his last acts to save his 'brother'. The Kravens do not realize they have killed the wrong 'spider' until later that night when Kraven recognizes the scent of Kaine, and they unmask the dead Spider-Man. As a result of this, Kraven is now undead and can only be killed by the original Spider-Man.