In 1982, a shady transaction is occurring between an East German scientist, Dr. Krause, and a group of Americans involving a substance known as MM88. MM88 is a deadly virus, created accidentally by an American geneticist, that amplifies the potency of any other virus or bacterium it comes into contact with. The Americans recover the virus sample, which was stolen from a lab in the US the year before, but the virus is accidentally released after the plane transporting it crashes, creating a pandemic initially known as the "Italian Flu".