"Zane" set sail from Chefoo, homeward bound, on 25 August and visited Nagasaki, Japan, on the first leg of her voyage back to the west coast of the United States. Subsequently, touching at Midway and Pearl Harbor, the destroyer reached San Francisco on 2 October. Shifting to the Mare Island Navy Yard on 9 October, "Zane" turned in all torpedoes, torpedo gear, and landing force equipment over the three days that ensued. She then fueled at Martinez, California, before reaching San Diego and San Pedro. Decommissioned at San Diego on 1 February 1923, "Zane" remained on "Red Lead Row" for seven years.