Dr. Katz is a professional psychotherapist. He is a laid-back, well-intentioned man who enjoys playing the guitar and spending time at the bar with his friend Stanley and bartender Julie. His patients are famous comedians and actors, usually two per episode, and the show is oriented around these sessions. Therapy sessions that feature comedians generally consist of onstage material while Dr. Katz offers insights or simply lets them talk. Therapy sessions that feature actors offer more interpersonal dialogue between Dr. Katz and his patient.