Kellerman starred with Ernest Borgnine and Mickey Rooney in "Night Club" (2011). Her performance as a woman with Alzheimer's disease living in a retirement home won an Accolade Competition Award for Best Supporting Actress. That year she played a recurring role as Lola (an eccentric artist) in Cinemax's sexually explicit comedy-drama series "Chemistry", followed by a guest appearances on the CW teen drama series "90210" as Marla, an aging Hollywood actress with dementia who considers assisted suicide. On July 7, 2012, Kellerman appeared with Tito Ortiz, Cary Elwes and Drake Bell in an episode of the Biography Channel's "Celebrity Ghost Stories".