In Katharine Graham's book "Personal History", she notes that her husband was always intense and spontaneous, but occasionally lapsed into periods of depression. In 1957, he had a severe manic episode and, at the time, no medicines were available for effective treatment. He retired to the couple's farm in Marshall, Virginia, to recuperate. Thereafter, periods in which he functioned brilliantly alternated with periods in which he was morose and erratic and isolated himself. He often drank heavily (something he had done prior to 1957), and would become extremely argumentative and blunt.