"Dreamsnake" won multiple awards, including the 1978 Nebula Award for Best Novel, the 1979 Hugo Award for Best Novel and the 1979 Locus Poll Award for Best Novel. It also won the Pacific Northwest Booksellers' Award, and was nominated for the 1979 Ditmar Award in International Fiction. In 1995, "Dreamsnake" was put on the shortlist for the Retrospective James Tiptree Award. "Of Mist, and Grass, and Sand" had won McIntyre her first Nebula Award, for best novelette, in 1974, as well as being nominated for the Hugo Award in the same category, and the Locus Award for Best Short Fiction. In 1980 the paperback was nominated for the American Book Awards.