The palace was remodelled in the Renaissance style in the 16th century. The plan was prepared by several Italian architects, including Giovanni Cini da Siena, Bernardino de Gianotis Zanobi, and others. The palace was visited by Ippolito Aldobrandini, who later became Pope Clement VIII. Another major development took place during the reign of the House of Vasa. The palace was refurbished in the early Baroque style during the rule of Sigismund III Vasa. Matteo Castello, Giacopo Tencalla, and other artists participated in the 17th-century renovation.