On November 6, 2010, Kunitz played his 400th career game and recorded a goal in that game against the Phoenix Coyotes. On March 15, 2016, he played his 800th career game and recorded a goal against the New York Islanders. In the 2016 Playoffs, he recorded 4 goals and 8 assists for 12 points, as the Penguins went to defeat the San Jose Sharks in six games in 2016. It would be Kunitz's third Stanley Cup of his career, his second with the Pens. Since 2010, he has been a regular member of the Penguins' top lines with Evgeni Malkin and/or Sidney Crosby. On May 26, 2017, Kunitz sent the Penguins to the Stanley Cup Finals with a double overtime game winner in Game 7 of the Eastern Conference Finals versus the Ottawa Senators. This would later become Kunitz's last career playoff goal. He became the oldest player to score a game 7 playoff series winning goal at the age 37. The Penguins faced off against the Nashville Predators in the 2017 Finals, defeating them in six games to successfully defend the Stanley Cup, with Kunitz assisting on the series-winning goal. This marked Kunitz's fourth Stanley Cup of his career, and his third as a member of the Penguins.