During 1862, various engagements between the hostile forces occurred in the vicinity of Neosho. In 1863, Neosho was garrisoned by Union troops, part of the time with American Indian soldiers occupying the courthouse. On October 4, 1863, a portion of the town was burned by Confederate General Joseph Shelby, who appeared with 1,100 men and, after shelling the courthouse, received the surrender of Union Captain McAfee and his 200 men. Confederate casualties in the fight were seven dead and 22 wounded.