Boyle spent the next two months preparing for his fifth and final privateering voyage. On 24 December, "Chasseur" put to sea and shaped a course for the West Indies. There, she took a succession of prizes. On 25 February 1815, she chased what appeared to be a weakly armed coaster but which turned out to be a Royal Navy cruiser. Undaunted, Boyle raced to the attack and, after a sharp 15-minute fight, captured HMS "St Lawrence". He was wounded during the capture and concluded his final cruise at Baltimore on 18 March 1815.