During his career, Frank taught and did research in departments of anthropology, economics, geography, history, international relations, political science, and sociology. He worked at nine universities in North America, three in Latin America, and five in Europe. He gave countless lectures and seminars at dozens of universities and other institutions all around the world in English, French, Spanish, Portuguese, Italian, German and Dutch. Frank wrote widely on the economic, social and political history and contemporary development of the world system, the industrially developed countries, and especially of the Third World and Latin America. He produced over 1,000 publications in 30 languages. His last major article, "East and West", appeared in the volume: "Dar al Islam. The Mediterranean, the World System and the Wider Europe: The "Cultural Enlargement" of the EU and Europe's Identity" edited by Peter Herrmann (University College Cork) and Arno Tausch (Innsbruck University), published by Nova Science Publishers, New York.