In 2006, Posey appeared in "Superman Returns" as Kitty Kowalski, Lex Luthor's ditzy sidekick, a character based on Eve Teschmacher from the 1978 film "Superman". Posey was the only actress considered for the role. "Superman Returns" was a box office success. The film was also successful at the 33rd Saturn Awards, Posey, a few fellow cast members, and the visual effects department were all nominated. Later the same year she played the title character in "Fay Grim", the sequel to "Henry Fool", and appeared in "For Your Consideration".