Huff was called up by the Devil Rays at the beginning of August to be the starting third baseman after Vinny Castilla suffered an injury. He had an RBI in his debut on August 2, a 5–3 loss to the Cleveland Indians. Two days later, he got his first career hit against José Mercedes in a 10–9 loss to the Baltimore Orioles. On August 10, he had a season-high three RBI by hitting his first career home run, a game-winning three-run hit against Jason Ryan in a 10–4 victory over the Minnesota Twins. In 39 games, Huff hit .287 with 35 hits, seven doubles, four home runs, and 14 RBI.