Tomei has appeared in a number of successful movies, including "What Women Want" (2000), "Anger Management" (2003), "Wild Hogs" (2007), "The Ides of March" (2011), and "Parental Guidance" (2012). Other films include "Untamed Heart" (1993), "Only You" (1994), "The Paper" (1994), "Unhook the Stars" (1996), "Slums of Beverly Hills" (1998), "Before the Devil Knows You're Dead" (2007), "Cyrus" (2010), "Love Is Strange" (2014), "The Big Short" (2015), "The First Purge" (2018) and "The King of Staten Island" (2020). She also portrays May Parker in the Marvel Cinematic Universe, having appeared in ' (2016), ' (2017), ' (2019), and ' (2019), she will return as the character in "" (2021).