Brown began his teaching career with positions at several universities, including Lincoln University and Fisk University, before returning to Howard in 1929. He was a professor there for 40 years. Brown's poetry used the south for its setting and showed slave experiences of the African American people. Brown often imitated southern African-American speech, using "variant spellings and apostrophes to mark dropped consonants". He taught and wrote about African-American literature and folklore. He was a pioneer in the appreciation of this genre. He had an "active, imaginative mind" when writing and "a natural gift for dialogue, description and narration".