Another key event in Canton's history came about in 1853 with the founding of "Christian University", now known as Culver-Stockton College. Closed for a period of time during the Civil War, the college reopened in 1865 and has been a foundation of the community since. Henderson Hall, a.k.a. "Old Main", on the Culver-Stockton campus is listed on the National Register of Historic Places. As a strategic river port, Canton was involved considerably in the Civil War. Loyalties were heavily mixed and both the Union and Confederate armies recruited heavily in the town and surrounding area. Federal troops occupied Canton in July, 1861 to quell recent unrest and quash recruiting for the Missouri State Guard and pro-Confederate guerrillas by Lewis county residents Martin E. Green, Joseph C. Porter and others. On August 2, 1862 Colonel Porter ordered a raid on Canton. One resident was killed and another, a Union sympathizer, kidnapped by the bushwhackers, who also stole large quantities of weapons, medicine and other supplies.