PA 152 was originally built as Limekiln Road in 1693. This road was used to transport lime from kilns in Upper Dublin Township. The road was maintained by adjacent property owners. In 1850, the Limekiln Turnpike Company was created to improve the roadway through the collection of tolls, boasting tollhouses at each end of the village of Dreshertown (now Dresher). The toll collection and tollhouses along the Limekiln Pike were abolished and removed in 1917. When Pennsylvania designated legislative routes in 1911, what is now PA 152 did not get a route number.