Skuse started the club's first 22 matches in the league in 2017–18, until he left a win against Reading at half-time on 16 December with an ankle injury. He scored his second goal for the club on 16 September 2017, producing a strike from the edge of the box in a 2–0 win over Bolton Wanderers at Portman Road. Skuse didn't find a consistent midfield partner until November, when Everton loanee Callum Connolly was given his first start there of the season. On 8 February 2018, Skuse signed a new two-year deal at Portman Road, keeping him at the club until the summer of 2020, with the option of a further year. His 200th appearance in all competitions for Ipswich came on 6 March against Sheffield Wednesday, and he was the only player signed by manager Mick McCarthy to have reached the benchmark during his tenure. Skuse made 39 starts that season, captaining the side on eight occasions through the absence of Luke Chambers, as Ipswich finished in mid-table.