In 2019, Mesa established a partnership with Co+Hoots, a private co-working business based in Phoenix, Arizona, to explore innovative educational opportunities, which includes establishment of a "certificate program in entrepreneurship". The partnership, which fits into the city's plan to create a "downtown innovation district", included renovation and expansion of Mesa's downtown campus facility at 225 E. Main Street to include space which would be provided "rent-free" to Co+Hoots as a commercial co-working space. Benedictine leases this downtown facility from the city, a lease which ends in 2038, with an option to purchase beginning in 2033.