Machado appeared in (and on the cover of) the February 2006 issue of "Playboy" magazine's Mexican edition, becoming the only Miss Universe to pose nude for that magazine. Machado was cast in the comedic soap opera "Una familia con suerte" where she played a woman who fell in love with her brother's enemy. The show began airing in Mexico in February 2011 and in the United States in October of that same year. She again posed nude for the July 2010 issue of the Mexican edition of "Playboy".