US 13 was designated through Maryland when the U.S. Highway System was established in 1926, running along existing roads. It formed a part of the Ocean Highway, a road that connected the New York City area to Florida, and still carries that name for much of its route in Maryland. Many realignments of the route occurred over the years. The route was realigned between Princess Anne and Fruitland in 1933 and between Westover and Princess Anne in 1935. Between 1938 and 1942, Salisbury Boulevard was built to carry US 13 through Salisbury; the route previously followed Camden Avenue and Division Street. In the 1950s, portions of the route were widened to a divided highway and a bypass of Delmar was built. US 13 was rerouted to bypass Princess Anne in 1959 and Pocomoke City in 1963. The remainder of US 13 in Maryland was widened into a divided highway in the 1960s. In 1973, construction began to build the limited-access Salisbury Bypass to the east of the city. US 13 was moved onto the completed Salisbury Bypass in 1981.