With the new year, 1944, "Roe" was transferred to the Pacific. Departing New York on 26 January, she transited the Panama Canal and traversed the Pacific to report to Commander, TF 76 at Cape Sudest on 12 March. From there, and other New Guinea ports and anchorages, she escorted 7th Phib Force ships transporting Allied troops up the coast and through neighboring islands, and provided gunfire support in target areas. From 16–21 March, she supported operations on Manus Island. In early April, she transported Army personnel from Manus to Rambutyo Island, then prepared for the landings at Humboldt Bay, which she supported on 22 April. In mid-May, she assisted the offensive in the Toem-Wakde area; then, at the end of the month, screened LSTs to Biak. Fire support duty and escort of reinforcements and supplies to Biak continued into June. On 29 April, she provided call-fire support for Army units fighting northeast of the Driniumor River. Then, in July, the destroyer shifted to Noemfoor to conduct a prelanding bombardment and to give postlanding support fire.