McCamey is named for George B. McCamey, whose 1925 wildcat well brought about the oil boom in the region. He brought in a real estate developer from Corpus Christi, to lay out a townsite near the oil field and along the Kansas City, Mexico and Orient Railway capable of housing 10,000 people. The town was initially a jumble of tents and frame shacks; order came slowly, replacing the lawlessness of the early boomtown environment. A post office was built in 1926, and the town was incorporated near the end of that year. In 1927, the McCamey Independent School District was formed, and an enterprising newspaperman printed the first issue of the "Tri-County Record", the first town newspaper.