Issaqueena, a young indigenous maiden who rode to Fort Ninety-Six to warn settlers of an attack, allegedly named some streams. Along her journey, she marked her travel by naming streams that she encountered for the number of miles she had covered. Issaqueena named Six-Mile, Twelve-Mile, Three-and-Twenty Mile and Six-and-Twenty Mile creeks, which are still a part of the lake today. Other historic figures who lived around this area were Andrew Pickens and John C. Calhoun, both statesmen from South Carolina. The botanist William Bartram traveled the area recording vegetation types and plant species.