For his lead role as Miles Roby in the 2005 miniseries "Empire Falls", Harris was nominated for the Primetime Emmy Award for Outstanding Lead Actor in a Miniseries or a Movie and the Golden Globe Award for Best Actor – Miniseries or Television Film. Also that year, he played a vengeful mobster in David Cronenberg's "A History of Violence" (2005) starring Viggo Mortensen. In 2006, he portrayed composer Ludwig van Beethoven in the film "Copying Beethoven", and starred in the television documentary film "The Armenian Genocide" as American diplomat Leslie Davis. He next appeared alongside Casey Affleck and Morgan Freeman in the Ben Affleck directed neo noir mystery film "Gone Baby Gone" (2007). Harris then co-starred as the antagonist Mitch Wilkinson in "" (2007), alongside Nicolas Cage.