The 2010 festival was held at Theater for the New City, back in the East Village. Using three theater spaces in the TNC complex, MIX emphasized an immersive environment with a string art design in the venue by Diego Montoya. One smaller theater contained a performative installation by Daniel Pillis. Another theater was turned into an installation lounge, anchored by Blaise Garber-Paul's Queer Fruit Tree, which grew and changed throughout the week, and under which visitors could sit on astroturf, or on conical black cushions. The closing night film was Bruce LaBruce's L.A. Zombie, which sold out, and a second screening was added.