Almirola moved up to the Busch series on a regular basis in 2007, driving the No. 18 and No. 20 Chevys for Joe Gibbs, driving each car in ten races apiece. He won his second career pole award for the Orbitz 300 at Daytona. He won the pole again, for the second straight year, at the AT&T 250 at the Milwaukee Mile, but thought he was going to give up driving duties to Hamlin again; Hamlin's helicopter was unable to land in time for Hamlin to make it to the track, so Almirola started the race, leading the first 43 laps of the race. On lap 59, during a caution period, because of sponsor commitments, Hamlin took over for Almirola while he was running in the third place. Hamlin went on to win the race, but Almirola was credited with his first NASCAR Busch Series win because he was the driver who started the race. Almirola did not participate in team victory celebrations after the race as he had already left the track. He soon joined Dale Earnhardt, Inc. following the sale of Ginn Racing. He drove the No. 01 Chevrolet in five races in 2007, and had the best finish of 30th.