The Lithonia Historic District consists of a commercial core surrounded by residential areas, with a period of significance spanning from 1845 to 1964. Stylistic influences in the district include Second Empire, Queen Anne, Folk Victorian, Neoclassical Revival, English Vernacular Revival, Craftsman, and Colonial Revival. The district is bisected by the Georgia/CSX Railroad, which runs perpendicular to the historic commercial core's primary thoroughfare, Main Street. The commercial area extends south from the intersection of Main Street and the railroad, covering a two-block area. The commercial buildings are primarily brick and local granite masonry, with little decorative detailing. Commercial styles include single retail, multiple retail, and retail and office types. Within the historic district, there is some non-historic infill construction such as the 1968 Lithonia Plaza shopping center.