Lowndes County was established by an act passed by the Georgia legislature on December 23, 1825. It was formed out of the 8th, 9th, 10th, 11th, 12th, 15th, and 16th land districts of Irwin County, Georgia. The county was named for William Jones Lowndes (1782–1822), a prominent South Carolina lawyer and Congressman. His father Rawlins Lowndes had been a Revolutionary War leader and was elected as South Carolina Governor. The Coffee Road was an improved trail first cut by Georgia militia to supply federal troops in Florida during the Creek Wars. It was the first route through the area of Lowndes County and opened up the area to white settlers.