The highlight of the 1907 season came early when he was handed the ball for opening day on April 11, 1907. The opponent was the Pittsburgh Pirates, led by the immortal future hall-of-famer Honus Wagner. Ewing pitched a complete game, four hit, 4-3 victory. In what he always viewed as the highlight of his career, Ewing fanned the first six Pirate batters he faced, including such outstanding hitters as Wagner, Fred Clarke and Ginger Beaumont. The Cincinnati Enquirer reported that "He used the spitball when he found himself in a tight place and it was very effective in his hands." The Reds come from behind with two runs in the ninth inning.