In addition to its original Greenwich Village location, on 7th Avenue near Bleecker Street, Jekyll and Hyde also operated a larger location on the Avenue of the Americas in Midtown near 57th street. This branch closed and moved to 44th Street, near Times Square in March 2012, which also closed March 2015. The Sixth Avenue facade continued to stand long after its closing, up to its demolition at around 2015. Other locations had been opened in Chicago and Grapevine, Texas (near DFW Airport), but closed due to poor business and the high operating costs of the restaurant.