Born a free person of color (free Negro) in New Hampshire, Wilson was orphaned when young and bound until the age of 18 as an indentured servant. She struggled to make a living after that, marrying twice; her only son George died at the age of seven in the poor house, where she had placed him while trying to survive as a widow. She wrote one novel. Wilson later was associated with the Spiritualist church, was paid on the public lecture circuit for her lectures about her life, and worked as a housekeeper in a boarding house.