Knowles has also presented programmes with a wildlife theme. In 2007, he fronted "Mission Africa", in which a team of volunteers constructed a game reserve in Kenya. During this project, Knowles fell from a Land Rover, dislocating his shoulder. He flew back to the UK to receive emergency treatment. In the same year, he reported on the plight of orphaned orangutans for an edition of "Saving Planet Earth". In 2009, Knowles co-presented the BBC reality TV series "Wildest Dreams" with James Honeyborne, in which novice candidates had to complete a set of challenging tasks filming wild animals in Africa. The winner joined the BBC Natural History Unit on a one-year placement.