Carrying out research in the music of Vedic age, he unravelled the mystery of Samic scale. To re-establish the lost notes of that period he created a Raga Sameshwari. Misra also first made it possible in history of mankind, the twenty-two Shruti-s (not to be confused with śruti, the genre of Vedic literature) to be distinctly heard on a single Veena. The invention and key to its function has been explained in “Shruti Veena” published on 11 February 1964 by Vikram Singh, Narendra Printing Works, Varanasi.