GalP is homologous to GLUT-1 found in mammalian cells (12). Both transporters are MFS transporters and possess 29% sequence identity (4). GLUT-1 is a glucose transporter present in most mammalian cells (Figure 5) (12). Its structure is nearly identical to that of GalP – possessing cytoplasmic amino and carboxy termini, twelve membrane spanning α helices, a periplasmic glycosylation site between helices 1 and 2, and a cytoplasmic α-helix loop between helices 6 and 7 (12). GLUT-1 ranges from 45 to 55 kDa; the size variation depends upon the extent of glycosylation (12).