Tytoona Cave's entrance is located in an approximately deep sinkhole. A stream emerges from the base of a sheer wall of the sinkhole opposite the cave entrance. This stream flows about one hundred feet or so before entering the Tytoona cave entrance. An above-ground stream, Sinking Run, enters the sinkhole and joins the stream emerging from the cliff. The flow of the above-ground drainage is very dependent on the amount of recent rain; the flow of the stream emerging from the base of cliff also varies greatly. The entrance to the cave slopes from ground level on the left diagonally to a high point of about 12 feet on the right. In the cave, the stream bottom is fairly flat and rather wide (~25 feet). The stream bottom is covered with gravel. The cave has a clay-covered path over a rock shelf on the left-hand side, with several very short dead-end passages on the left.