In alternative medicine, red clover is promoted as a treatment for a variety of human maladies, including symptoms of menopause, coughs, disorders of the lymphatic system and a variety of cancers. Several systemic reviews and meta-analyses concluded that red clover extract reduces the frequency of menopause hot flashes. Most added that further research is needed to confirm the results. There is no evidence in the human trial literature that red clover has been tested for effects on cough, lymphatic system or cancer prevention/treatment. Dietary amounts of red clover are safe, but dietary supplement extracts may cause rash-like reactions, muscle ache, headache, nausea, vaginal bleeding in women, and slow blood clotting.