From Messina Louis led a naval and land campaign against Palermo, but succeeded only in devastating the countryside. By September he was able to return to Catania. He was struck by the plague, moved to Aci, a castle belonging to the recently deceased Frederick of Randazzo. There he died on 16 October, only seventeen years of age. That same night his body was moved to the church of Santa Maria la Grande outside the walls of Catania. The next day (17 October) his funeral procession passed through the streets to the cathedral of Sant'Agata, where his body was placed in the same tomb as his grandfather, Frederick II (III), and uncle, John of Randazzo.