Lexie entertained several relationships throughout her time on "Grey's Anatomy". In her early appearances, she maintained a strong friendship with George O'Malley until she began developing romantic feelings for him. Rhimes offered the insight: "I love them as friends. They make good friends. We all have that friend we met in school or the gym or somewhere – we just hit it off right away. And right away there was no pretense or airs. Just pure honesty. That's Lexie and George. They're really good friends and I can see the friendship evolving into something even greater. At least, that's what Lexie is hoping. She is my kind of girl. The girl who likes the guy because he is a GOOD guy and that's what George is. He is a good guy and that's something that Lexie could use now. She's going through her own challenges what with Meredith and losing her own mother and trying to keep things afloat. I'm rooting for Lexie. She's my kind of girl and I hope that she gets what she deserves: love. And more kisses. There should always be that."