The enormous altarpiece of the main altar was begun by Pedro Berruguete in the transition from the 15th to the 16th century. He carried out eight predellas portraying in detail and naturalism images of Evangelists and Doctors of the Church, as well as two boards portraying the "Prayer in the Garden" and the "Flagellation". These paintings, perhaps reflecting the prevailing style in Castile at the time, use gold backgrounds and somewhat rigid compositions. After his death, his assistant, Santos Cruz, continued the work with "the Crucifixion", "the Resurrection" and the "Epiphany". The rest of the scenes were carried out by Juan de Borgoña.