Route 33 Business begins at the interchange with Route 33, its parent route, in Manalapan Township, New Jersey. A short distance after, the interchange from Route 33 eastbound merges into Route 33 Business, and the route passes to the south of Monmouth Battlefield State Park and enters Freehold Township. Soon after entering the borough of Freehold, Route 33 Business interchanges with U.S. Route 9. Route 33 Business turns to the southeast, passing to the north of Freehold Raceway. A short distance later, Route 33 Business intersects at a traffic light with New Jersey Route 79 (South Street) in downtown Freehold. At the intersection with Fairfield Road, Route 33 Business enters the interchange with Route 33 and the freeway, where the designation terminates.