Also in 2004, she had a supporting role as Jocelyne Jordan in the political thriller "The Manchurian Candidate", which also starred Denzel Washington and Meryl Streep. The following year, she co-starred in the fantasy drama "Neverwas" with Aaron Eckhart and Ian McKellen, which premiered at the 2005 Toronto International Film Festival. Farmiga then appeared alongside Leonardo DiCaprio and Matt Damon as police psychiatrist Dr. Madolyn Madden in Martin Scorsese's crime drama "The Departed" (2006). For her performance as Madolyn, Farmiga was nominated for the Empire Award for Best Newcomer, and shared with her co-stars the nomination for the Screen Actors Guild Award for Outstanding Performance by a Cast in a Motion Picture.