Harriott embarked on a solo career and later formed his own record label, Crystal. His first solo release, "I Care", was a hit, with further hits following with "What Can I Do" (1964), "The Jerk" (1965) and "I'm Only Human" (1965), all of which were included on his debut album, "The Best of Derrick Harriott". In 1967 he had further solo hits with "The Loser" and "Solomon", as well as with productions of other artists, including The Ethiopians' "No Baptism", and Keith And Tex's "Tonight" and "Stop That Train".