SR 527 begins as a continuation of the Bothell–Everett Highway at a partial cloverleaf interchange with I-405 in northern Bothell, located in Snohomish County. The interchange is located adjacent to the Canyon Park park and ride, a major bus transfer facility. The highway travels northeast through the Canyon Park business park and turns north after crossing North Creek, following it to a junction with SR 524 at Thrasher's Corner. SR 527 then crosses into the unincorporated North Creek area, which is filled with suburban homes and apartment complexes that line the road, along with commercial areas at Kennard Corner and near North Creek County Park.