The same year he was again denounced to the Inquisition on the grounds of his "Commentary" (although, in 1563 it had received the approval of the Commission of the Council of Trent). He had evidently lost favour with Philip, by whose order he was arrested at Torrelaguna in 1559 and imprisoned for nearly eight years, and the book was placed on the "Index". The process dragged on. Carranza appealed to Rome, was taken there in December 1566, and confined for ten years in the castle of St. Angelo. He was defended in the proceedings by Navarrese fellows Francisco de Navarra, archbishop of Valencia (close friend of his) and Martin de Azpilcueta, from Barasoain.