Moreton Bay College was founded in 1901 by Miss Alice J. Alison Greene and her sister Anne, in a school specially designed and built by their father. Its location was in the heart of Wynnum town, on Bay Terrace, bounded by Charlotte and Florence Streets. The school was originally called Moreton Bay Girls' High School and was intended to provide, in addition to classrooms and other rooms, boarding facilities for thirty boarders. The first roll contained six boarders and twenty day scholars.