After the end of her marriage to Rourke, Otis gradually resumed modeling. In 2000, she became one of the oldest models to appear in the "Sports Illustrated" swimsuit issue, although Christie Brinkley at 34 and Cheryl Tiegs at 42 were featured prominently in the 25th Anniversary edition of"Sports Illustrated", released in 1989. Shortly thereafter, Otis began recovering from anorexia nervosa. As part of her recovery, she experienced a weight gain that offered her the opportunity to work as a plus-size model, most notably as the face for Marina Rinaldi and editorials for "Mode" Magazine; in 2003, Otis became a spokesperson for National Eating Disorders Awareness Week. She also appeared periodically as a correspondent on Channel 4 News in San Francisco.