Her next film was the crime drama "The Opportunists" (2000), in which she co-starred as Miriam Kelly, the daughter of Christopher Walken's character. The following year, Farmiga had a supporting role as Daphne Handlova in the action thriller "15 Minutes" alongside Robert De Niro, and co-starred in the drama film "Dust", which premiered at the 2001 Venice Film Festival. Farmiga subsequently joined the main cast of NBC's short-lived procedural drama series ' as Alex Cross. The series premiered in September 2001, and was cancelled after one season. She then appeared in the Hallmark fantasy television film '.