Molecular analyses of partial sequences of 16S rDNA of 18 distinct species carried out by Sutcharit and colleagues (2007) indicate that "Amphidromus" is a monophyletic group. In their study, different cladograms obtained through distinct methods such as maximum parsimony, neighbor joining and maximum likelihood were congruent among themselves. Though the topology obtained for the subgenus "Amphidromus" was fairly consistent with current taxonomy, the phylogeny of sinistral "Syndromus" species showed no such correspondence. Also according to their results, enantiomorphy seems to be the ancestral state of shell coiling in the genus "Amphidromus", which is contrary to the general expectation of dextrally coiled shells as an ancestral condition.