Branyan was placed on the bereavement list following the death of this father-in-law on April 27. This made room for catcher Josh Bard on the roster. He was activated on May 3 and the Padres sent Pete Laforest outright to the Triple-A Portland Beavers to make room for Branyan on the roster. On May 12, in a win over the St. Louis Cardinals, Branyan hit two home runs. The first was against Kip Wells, and the second against Brian Falkenborg. Branyan hit a go-ahead home run at Wrigley Field against the Chicago Cubs in a 1–0 win on June 16. In 2007, Branyan batted .197 with five doubles, one triple, seven home runs and 19 RBIs in 61 games for the Padres before his release on July 28. The release made room for Scott Hairston on the Padres' roster.