Pope John XXIII Regional High School has a Catholic philosophy in accordance with Church teaching. The school also has a college prep course of study in academic subjects. Students are required to not only take state required courses but an additional year of Math and Science. Theology coursework is required for every marking period a student is enrolled at the school. Two years of a foreign language such as Spanish, French, Italian, and Latin are also required as well as computer courses. Seventeen Advanced Placement (AP) courses are offered. An eighth grade honors program for math, history, english and science is also offered The math and science taught to the eighth grade honors students is also taught to the freshman. The school's music department was founded in the mid-1970s by John-Michael Caprio, who would go on to be director of music at New York City's St. Patrick's Cathedral in the 1990s. In addition to the eighth grade honors program for area Catholic schools, Pope John launched their own eighth grade class in the 2009–2010 academic year, but only accepted eighth grade students who were previously from public schools.