On 13 September 2016, in the opening 2016–17 Champions League Group A match against Arsenal at the Parc des Princes, Cavani scored after just 44 seconds had elapsed in the first half by heading in Serge Aurier's cross from the right for PSG's fastest-ever Champions League goal. The match ended in a 1–1 draw. On 16 September, Cavani scored four times (his first ever four-goal haul with PSG) in the first half as PSG trounced Caen 6–0 away in a Ligue 1 match to end PSG's streak of three competitive matches without victory, two of them in Ligue 1. On 30 November, he scored a penalty in a 2–0 home win against Angers to take his Ligue 1 tally to 14 goals in 14 matches, which also saw him become only the fourth player in PSG history to score 100 competitive goals for the club.