A UK DVD from Anchor Bay was released in 2004. On 25 January 2011, Severin Films gave the film a release on both DVD and Blu-ray with more than "five hours of exclusive extras". On Halloween 2019, Morbido Fest, a Mexico City-based festival, held a celebratory 30th anniversary screening of "Santa Sangre"; remastered in 4K by Severin Films from a scan of the original camera negative. In Italy, from 25 to 27 November 2019, the Videa film society celebrated the 30th anniversary by screening the 4K restored version at select theatres.