Many lichens are very sensitive to environmental disturbances and can be used to cheaply assess air pollution, ozone depletion, and metal contamination. Lichens have been used in making dyes, perfumes, and in traditional medicines. A few lichen species are eaten by insects or larger animals, such as reindeer. Lichens are widely used as environmental indicators or bio-indicators. When air is very badly polluted with sulphur dioxide, there may be no lichens present; only some green algae can tolerate those conditions. If the air is clean, then shrubby, hairy and leafy lichens become abundant. A few lichen species can tolerate fairly high levels of pollution, and are commonly found in urban areas, on pavements, walls and tree bark. The most sensitive lichens are shrubby and leafy, while the most tolerant lichens are all crusty in appearance. Since industrialisation, many of the shrubby and leafy lichens such as "Ramalina", "Usnea" and "Lobaria" species have very limited ranges, often being confined to the areas which have the cleanest air.