Doolgunna homestead and flows for approximately . The Gascoyne flows generally west by southwest and is joined by 36 tributaries including the Lyons River, Landor River, Thomas River, and numerous other creeks and gullies. The two main rivers, the Gascoyne and Lyons together provide a catchment area of that lies entirely to the east of the Kennedy Ranges and extends some inland. The river reaches its mouth as it flows into Shark Bay and the Indian Ocean at . The river descends over its course.