Bush was injured in the October 19 game against the Carolina Panthers. He had surgery to repair a torn meniscus in his left knee the next day and was expected to miss the next three to four games. Bush returned on November 30 against the Tampa Bay Buccaneers and registered three carries for no yards and five catches for 32 yards in a 23–20 Saints loss. However, one week later he was back on track, producing over 100 yards from scrimmage and a touchdown catch in an important 29–25 home win against the division rival Atlanta Falcons to keep the Saints' slim playoff hopes alive.