OCMA opened its temporary space at South Coast Village on October 3, 2018 which has served as its interim home during the construction of the permanent Segerstrom Center facility. Known as OCMA Expand Santa Ana (stylized as OCMAEXPAND-SANTA ANA), the site features exhibition seasons of approximately six months each in duration. The museum was temporarily closed on March 14th, 2020 in accordance with quarantine efforts in response to the COVID-19 breakout in the United States. The facility was once again shuttered on November 16th, 2020 admist what local health officials described as a "second wave" of the virus in Orange County. The museum originally announced that the seasons would continue through at least March 2021; however, COVID-19 related delays have made the future timeline of the temporary site unclear.