The year 1859 was Catawba's peak in the Ohio wine industry, with the state being the largest producer in the United States, producing more than of wine from acres of mostly Catawba vines. But the 1860s brought an end to the enthusiasm when powdery mildew decimated Catawba plantings and the economic turmoil of the American Civil War led to many vineyards being pulled up or abandoned. Another "labrusca" variety, the Concord developed in 1849 in Concord, Massachusetts by Ephraim Wales Bull soon eclipsed Catawba in plantings and ended its dominance of the American wine industry.