When Poland regained its independence as the Second Polish Republic, Radzyń was the seat of a county in Lublin Voivodeship. The town was briefly occupied by the Russians during the Polish–Soviet War in mid-August 1920, and recaptured by Poles on August 16, 1920. The town had a large Jewish minority, and houses of the lower classes were mostly built from wood, which resulted in a large fire in 1930. The houses on the market square were later rebuilt of stone and brick.