WIS 64 becomes Main Street in Gilman, intersecting with IWS 73 east of the village. WIS 64 and WIS 73 continue south across the Yellow River before WIS 73 continues south towards Thorp. WIS 64 runs along the southern border of Chequamegon National Forest en route to Medford, where it becomes Broadway Avenue. WIS 64 then crosses WIS 13 at 8th Street on the east side of the city. Outside of the unincorporated town of Goodrich, WIS 64 meets the northern terminus of WIS 97 (Mink Drive). WIS 64 continues slightly northwest into Goodrich before entering Lincoln County. WIS 64 continues on for about before intersecting WIS 107. WIS 64 and WIS 107 continue north for before turning east and into the city of Merrill, where they become Main Street.