In 2005, Pierce joined Tim Curry and others in the stage production of "Spamalot". In August and September 2006, he starred as "Lieutenant Frank Cioffi" in "Curtains", a new Kander and Ebb musical staged at the Ahmanson Theatre in Los Angeles. In March 2007, "Curtains" opened on Broadway and on June 10, 2007, Pierce won the Tony Award for Best Performance by a Leading Actor in a Musical at the 61st Tony Awards for his performance. In his acceptance speech, Pierce said the first words he spoke on a Broadway stage were, "I'm sorry, I'm going to have to ask you to leave."