Huff, in the 11th year of his career, reached the playoffs for the first time as the Giants won the NL West. In Game 4 of the NL Division Series (NLDS) against the Atlanta Braves, he had a ninth-inning, two-out, game-tying RBI single against Mike Dunn in a 3–2 Giants' victory. He batted .267 with four hits and one RBI in the series as the Giants defeated the Braves in four games. He batted .250 with six hits and three RBI in the series as the Giants defeated the Phillies in six games. In Game 4 of the World Series against the Texas Rangers on October 31, he hit a game-winning two-run home run against Tommy Hunter in a 4–0 Giants' victory. He batted .294 with five hits, a home run, and four RBI in the series, winning his first World Series as the Giants defeated the Rangers in five games to win their first World Series in 56 years.