SR 103 begins at an interchange with I–75, on the south side of Bluffton. The route heads northwest as a two-lane highway crossing over a railroad track. The road passes through residential properties, before turning northeast towards downtown Bluffton. In downtown Bluffton the highway passes on the northwest side of Bluffton University, before the road turn toward the southeast. As the route heads southeast it passes over the railroad track again, followed by a curve due east. After the curve is the second interchange with I–75, in a commercial area of Bluffton. The highway passes the Bluffton Airport and leaves the village of Bluffton. East of Bluffton the route passes through farmland and has an intersection with SR 235, in rural Hancock County. The route enters Arlington, passing through mostly residential properties. In the center of the village SR 103 has an intersection with U.S. Route 68 (US 68).