Because of several knee injuries in the early part of the 2010 season, he finally made a return, beginning at the 2010 Copa Telmex, his hometown tournament. He beat Potito Starace in the first round 6–2, 7–6, over a period of two days due to a rain delay. In the second round, he beat Daniel Gimeno-Traver 6–7, 6–4, 7–6. However, he pulled out of his quarterfinals match against fifth seed Albert Montañés due to a right leg injury. He made a return to tennis by playing doubles for Argentina in the Davis Cup against Sweden in Stockholm, which he won in straight sets. He played the deciding singles rubber, defeating Vinciguerra 7–5, 6–3, 4–6, 6–4, and helped Argentina reach the quarterfinals.