Bypassing the Salisbury area to the east, the route heads through farmland and meets MD 513 (St. Lukes Road) at a diamond interchange. MD 513 provides access from the US 13 bypass into Fruitland. Continuing northeast through a mix of farmland and woodland, with some housing developments nearby, US 13 meets MD 12 (Snow Hill Road) at a partial cloverleaf interchange. MD 12 serves as a direct link between Salisbury and Snow Hill, connecting with US 113 in Snow Hill. Turning north upon crossing Beaverdam Creek near Parker Pond, the highway crosses over MD 350 (Mt. Hermon Road) with no interchange between the routes, and continues north to another partial interchange with US 50 and US 50 Bus. to the east of Salisbury.