Hurricane Isbell was the final hurricane to affect the United States during the 1964 season. The eleventh tropical storm and sixth hurricane of the season, Isbell developed from a dissipating cold front in the southwestern Caribbean Sea on October 8. The depression initially remained disorganized as it track northwestward, but strengthened into Tropical Storm Isbell on October 13. Re-curving northeastward, Isbell quickly strengthened further and reached hurricane status by later that day. Late on October 13, Isbell made landfall in the Pinar del Río Province of Cuba. The storm continued strengthening and peaked as a Category 3 hurricane on the following day. Isbell moved northeastward and made landfall near Everglades, Florida, late on October 14. After reaching the Atlantic on the following day, the storm began to weaken. Isbell turned northward and continued weakening, before transitioning to an extratropical cyclone while located just offshore eastern North Carolina on October 16.