Born at Whitby, Ontario in 1862 as Georgina May Campbell, her father, Robert E. Campbell, died when she was 13 years old; her stage-minded mother, Sophoria Jane Draper, in need of money, encouraged May and her older sister Adeline Flora ("Flo" or "Addie") to perform. They created a singing act, billed as the "Irwin Sisters," that debuted at the Adelphi Theatre in nearby Buffalo, New York in December 1874. By late 1877, their careers had progressed and they were booked to appear at New York's Metropolitan Theater, then at the Tony Pastor Theatre, a popular New York City music hall.