She was signed by the American producer Henry Miller and made her Broadway debut in New York City in 1906 to critical and popular success. Her English-language premiere in November 1906 was in the title role of "Hedda Gabler". She quickly became extremely popular (Nazimova's 39th Street Theatre was named after her) and remained a major Broadway star for years, often acting in the plays of Henrik Ibsen and Anton Chekhov. Dorothy Parker described her as the finest Hedda Gabler she had ever seen.