One of Bradley's notebooks records his stays in Oberlin, Ohio, and West Haven, Connecticut, between 1847 and 1850. In January 1848, Bradley became associated with the American Missionary Association (AMA) that had just been founded in Albany, New York on 3 September 1846. It was at Oberlin College that he met Sarah Blachly, who became his second wife on 1 November 1848 in Dane, Wisconsin. At the end of October 1849, they set sail for Siam and, after a voyage even more difficult than the first, he was able to resume his calling in Bangkok by the end of May 1850. Sarah Bradley died 16 August 1893, never once having left Thailand. They had the following children: Sarah Adorna Bradley, born 8 April 1850 in Singapore; Dwight Blachly Bradley, 13 October 1852 in Bangkok, died 10 September 1939 in Northboro, Massachusetts; Irene Belle Bradley, 19 May 1860 in Bangkok, where she died in 1943, unmarried.