Industry began in the area as early as the 17th century. The first brewery was established at the foot of Parker Hill in the 1820s. By the 1870s beer production was the main industry in Mission Hill, and many breweries lined the Stony Brook (now a culvert running along the Southwest Corridor). Most of Boston's breweries were once located in Mission Hill, but three periods of Prohibition (1852–1868, 1869–1875 and 1918–1933) and the nation's transition from local breweries to national mass-produced brands took their toll on business. Many of the remaining buildings are now being converted into loft condominia.