On March 12, 2016, Stepheson signed a 10-day contract with the Memphis Grizzlies to help the team deal with numerous injuries. Memphis had to use an NBA hardship exemption in order to sign him as he made their roster stand at 17, two over the allowed limited of 15. In just his second game for the Grizzlies on March 14, Stepheson recorded 12 points and 15 rebounds in 25 minutes off the bench against the Houston Rockets, playing extended minutes due to the team's injury depleted roster. On March 22, following the conclusion of his 10-day contract, the Grizzlies parted ways with Stepheson. The following day, he returned to Iowa. At the season's end, he was named to the All-NBA D-League First Team.