Synthetic fertilizer used in agriculture has wide-reaching environmental consequences. According to the IPCC Special Report on Climate Change and Land, production of these fertilizers and associated land use practices are key drivers of global warming. The use of fertilizer has also led to a number of direct environmental consequences: agricultural runoff which leads to downstream effects like ocean dead zones and waterway contamination, soil microbiome degradation, and accumulation of toxins in ecosystems. Additionally, use of synthetic fertilizers can have significant indirect environmental impacts as well: for example, the environmental impacts of fracking for natural gas used in the Haber process, the agricultural boom is partially responsible for the rapid growth in human population and large-scale industrial agricultural practices are associated with habitat destruction, pressure on biodiversity and agricultural soil loss.