Following this intersection, the road becomes East Kings Highway and runs along the border between West Brandywine Township to the north and Valley Township to the south as it runs through forested areas with some homes. The route enters Caln Township and heads southeast, passing over the US 30 freeway. PA 340 intersects Reeceville Road/North Caln Road, with Reeceville Road heading north to an interchange with US 30. The road curves northeast and comes to another bridge over US 30. The route passes through more wooded areas with some homes and fields, as well as Caln Meeting House, turning east onto Bondsville Road. PA 340 runs through forested areas and makes a turn to the south, coming to an interchange with US 30. The route runs through wooded areas of residential development and comes to its eastern terminus at an intersection with US 30 Bus. (Lincoln Highway) in the community of Thorndale.