In September 2015, research by MAP published in "Nature" quantified the attributable effect of malaria disease control efforts in Africa. The results showed "Plasmodium falciparum" infection prevalence in endemic Africa halved and the incidence of clinical disease fell by 40% between 2000 and 2015. The best estimate is that interventions have averted 663 million clinical cases since 2000. Insecticide-treated nets, the most widespread intervention, were by far the largest contributor. Although still below target levels, current malaria interventions have substantially reduced malaria disease incidence across the continent.