In October 2011, it was announced that Tyler would join the cast of "The Talk" as a permanent co-host, replacing Holly Robinson Peete. Her first full week as a co-host was October 24 through October 28, 2011. Tyler is known for being expressive and outspoken on The Talk, especially about African American culture and stereotypes, LGBT rights, and women's rights. Tyler presented Ubisoft's press conference at E3 2012 in June, which received some backlash from fans who didn't believe Tyler was a gamer. This caused Tyler to respond with a poem about how she has been playing video games "since you were a twinge in the left side of your daddy's underoos". She returned to host the publisher's press conference the following year. Tyler's second book, "Self-Inflicted Wounds: Heartwarming Tales of Epic Humiliation", debuted in July 2013, later becoming a "New York Times" bestseller; it was inspired by questions asked of guests on "Girl on Guy".