The show centers on FBI special agents Fox Mulder (David Duchovny) and Dana Scully (Gillian Anderson) who work on cases linked to the paranormal, called X-Files. Mulder is a believer in the paranormal, while the skeptical Scully has been assigned to debunk his work. In this episode, Scully leaves town—and Mulder—for a solo assignment. She soon meets Ed Jerse, a man who is being mentally controlled by a drug-related side effect of his tattoo. His tattoo, affectionately named Betty, does not want to share him, especially not with Scully.