Cholmeley's brother, Roger, had a son whom he named Richard, whose descendants are the Cholmeleys of Roxby, Bramston and Whitby. This is the line of the current 7th Baronet, Sir Frederick Sebastian Cholmeley of Easton Hall, Grantham, Lincolnshire. Cholmeley's cousin, Richard Cholmondeley of Cholmondeley, Cheshire, was married to Elizabeth Brereton of Malpas, whose brother, William Brereton, was executed in 1536 on suspicion of being Anne Boleyn's lover. That branch of the family's descendants, beginning with Sir Hugh Cholmondeley, included the Marquesses and Earls of Cholmondeley.