Gutenberg's movable-type printing system spread rapidly across Europe, from the single Mainz printing press in 1457 to 110 presses by 1480 – 50 of them in Italy. Venice quickly became the center of typographic and printing activity. Significant contributions came from Nicolas Jenson, Francesco Griffo, Aldus Manutius, and other printers of late 15th-century Europe. Gutenberg's movable type printing system offered a number of advantages over previous movable types The lead-antimony-tin alloy used by Gutenberg had half the melting temperature of bronze, making it easier to cast the type and aided the use of reusable metal matrix molds instead of the expendable sand and clay molds. The use of antimony alloy increased hardness of the type compared to lead and tin for improved durability of the type. The reusable metal matrix allowed a single experienced worker to produce 4,000 to 5,000 individual types a day, while Wang Chen had artisans working 2 years to make 60,000 wooden types