The Royal Canadian Air Force first acquired 15 DHC-5A designated as CC-115 for tactical transports. These were initially operated at CFB St Hubert, QC by No. 429 Squadron in a tactical aviation role as part of Mobile Command. In 1970, the Buffalo aircraft were transferred to a transport and rescue role with No. 442 Squadron, No. 413 Squadron and No. 424 Squadron as part of Transport Command. No. 426 Squadron also flew the aircraft for training. Some were leased back or loaned back to the factory for trials and eventually returned to military service.