In 1911, what would become PA 63 was designated as Legislative Route 198 between Green Lane and Philadelphia. By 1927, PA 63 was designated to run from PA 29 in Green Lane to US 611 (now PA 611) in Willow Grove, following its current alignment. PA 63 was extended east to PA 532 in Philadelphia in 1928, following its current alignment between US 611 and Edge Hill Road in Willow Grove. From this intersection, the road followed Edge Hill Road and Terwood Road east before following Welsh Road to an intersection with PA 163/PA 232 in Bethayres and following Philmont Avenue between PA 163/PA 232 and PA 532.