"Trilophosuchus" is representative of an early Cenozoic radiation of mekosuchines in Australia. Other mekosuchines that lived in Australia at the time included "Pallimnarchus", "Australosuchus", and "Quinkana". "Pallimnarchus" and "Australosuchus" were broad-snouted, generalized crocodylians, while "Quinkana" was ziphodont, meaning it had a deep snout. "Trilophosuchus" is unusual among mekosuchines, and crocodilians in general, in that it had a short-deep snout and an arboreal lifestyle. It represented a third adaptive type in the early radiation of Australian mekosuchines. All of these early mekosuchines were terrestrial, unlike their semiaquatic crocodile relatives.