Madison had served as Secretary of State since President Thomas Jefferson took office in 1801. Jefferson, who had declined to run for a third term, threw his strong support behind Madison, a fellow Virginian. Sitting Vice President George Clinton and former Ambassador James Monroe both challenged Madison for leadership of the party, but Madison won his party's nomination and Clinton was re-nominated as vice president. The Federalists chose to re-nominate Pinckney, a former ambassador who had served as the party's 1804 nominee.