She persuaded Tōshirō Hitsugaya, while he was still residing in Rukongai, to join the Gotei 13 to gain control over his spiritual pressure. The two of them have grown close ever since. Although Hitsugaya always bickers about her drinking habit and laziness, she has an unwavering loyalty and devotion to him and frequently tries to get him to lighten up, despite his serious attitude. Before Hitsugaya, Rangiku also had a close relationship with her former captain, Isshin Shiba, who is just as lazy as herself. She often foisted her responsibilities onto Isshin, who would then retaliate in kind.