In 2001 and still riding for Festina, Moreau won the prestigious stage race the Critérium du Dauphiné Libéré. Moreau took the lead on the fifth stage by only one second over Russian Pavel Tonkov. On the following day, both finished together second and third on the stage where there were no seconds awarded at the stage finish. Moreau withstood the many attacks of Tonkov on the final stage to win the race. Several weeks later, he won the prologue of the 2001 Tour de France and put on the yellow jersey as leader of the general classification. Moreau was presented with the yellow jersey by two podium girls. One of which he began a relationship after meeting on the Tour podium and would later marry. Moreau ended the Tour prematurely when he withdrew on the 12th stage. Festina choose to end its sponsorship of a cycling team so Moreau joined Crédit Agricole.