The Great River Road enters Tennessee on US 61, following that highway along 3rd Street into Downtown Memphis. The National Route historically crossed the Memphis & Arkansas Bridge, meeting 3rd Street at Crump Boulevard. The route follows a number of city streets along the riverfront: G.E. Patterson Avenue, Main Street, Beale Street, Riverside Drive, Jefferson Avenue, Front Street (passing the Pyramid), the A.W. Willis Bridge, Island Drive, Mud Island Drive, Second Street, and Whitney Avenue, joining US 51 in northern Memphis. It soon turns off on SR 388, and then follows a sequence of local roads past Meeman-Shelby Forest State Park: Locke Cuba Road, Bluff Road, Riverbluff Road, Herring Hill Road (which is partly unpaved), Pryor Road, and Richardson Landing Road. At Richardsons the route turns east with SR 59 to Covington, then runs north on US 51.