Set in New York City, the series stars Gale Storm as 21-year-old Margie Albright and former silent film star Charles Farrell as her widowed father, 50-year-old Vern Albright. They share an apartment at the Carlton Arms Hotel. Vern Albright is the vice-president of the investment firm of Honeywell and Todd, where his bosses are George Honeywell (Clarence Kolb) and Westley Todd (George Meader). Roberta Townsend (Hillary Brooke) is Vern's girlfriend, and Margie's boyfriend is Freddy Wilson (Don Hayden). Mrs. Odetts (played by Gertrude Hoffmann on TV, Verna Felton on radio) is the Albrights' next-door neighbor and Margie's sidekick in madcap capers reminiscent of Lucy and Ethel in "I Love Lucy". When Margie realizes she has blundered or gotten into trouble, she makes an odd trilling sound.