Having missed the opening game of the season, due to an injury, Reginiussen made his Tromsø debut, starting the whole game, in a 1–0 against Stabæk on 17 April 2006. Since joining the club, he quickly became a first team regular for the side, playing in either the midfielder and defender positions. After serving a one match suspension, Reginiussen scored on his return, in a 3–1 win against Brann on 24 September 2006. At Alfheim, Reginiussen was an instant success, and after his first season with Tromsø, he was voted "Player of the Year" by the supporter club Isberget. Reginiussen went on to make twenty–five appearances and scoring once in all competitions.