In 2002, LaPaglia co-starred as a fire captain opposite Sigourney Weaver in "The Guys", a film about New York firemen who died in the World Trade Center. He also played the role onstage, rotating with Bill Murray and others. "We did it as a tribute to the men," said LaPaglia. "I've been so lucky to do it, to be part of this experience. But I can't go back to that morning or watch the video. It's too painful." He also played fictional Australian actor Anthony Bella (who played Nicky Caesar in the fictitious series "Little Caesar") in the comedy movie "Analyze That", but was uncredited in his role.