In the right presbytery, is the Spada family chapel completed in 1593 by Rainaldi. Inside, a "Madonna with Child and Santi Carlo Borromeo and Ignazio di Loyola" (1675) was painted by Maratta. In the central presbytery, the bronze ciborium was designed by Ciro Ferri in 1681. The "Virgin with child" and two lateral paintings, "Santi Domitilla, Nereo and Achilleo", "Santi Gregorio Magno, Mauro and Papia" (1606–08) are among the few works painted by Peter Paul Rubens created specifically for a Roman commission. When installed, the three slate panels are said to have caused a 'stir' among observers in Rome, who were generally unaccustomed to the Flemish painterly style. The Rubens altarpiece was commissioned by Monsignor Jacopo Serra for 300 scudi.