Jackson joined the WHAS Crusade for Children in 2005, the first person from outside the WHAS-TV corporate structure to hold the post. She was instrumental in establishing an endowment for the telethon, funded by bequests from people who left donations to the Crusade in their wills. The endowment is designed to fund the day-to-day operating expenses of the organization, allowing 100 percent of the donations collected from the general public to go directly to agencies providing direct services to children with special needs.