A 1920s building boom in Carrboro sparked by a fire in the downtown business district ended as business at the Durham Hosiery Mills declined towards the end of the decade. The Great Depression also took an economic toll and in 1930 the company closed Mill No. 4, the original Alberta Cotton Mill. Passenger service on the train line ended in 1936. In 1938 Durham Hosiery Mills closed Mill No. 7, across Main Street from Mill No. 4, and ceased operations altogether.