EVA is also used in biomedical engineering applications as a drug-delivery device. The polymer is dissolved in an organic solvent (such as dichloromethane). Powdered drug and filler (typically an inert sugar) are added to the liquid solution and rapidly mixed to obtain a homogeneous mixture. The drug-filler-polymer mixture is then cast into a mold at −80 °C and freeze-dried until solid. These devices are used in drug delivery research to slowly release a compound. The polymer does not biodegrade within the body, but is quite inert and causes little or no reaction following implantation.