The third set of volumes refers to the years 1758 through 1762. It corresponds with the family's return to South Carolina and soon after, the death of her husband. She was left widowed and in charge of overseeing her family's plantations along with her late husband's as well. She lived as a widow for more than thirty years until her death in 1793 while she was searching for a cure for breast cancer. Though she continued to keep copies of her letters after her husband died, very few of them remain today.