Solano was solemnly professed in 1569. He was then sent to the friary of Our Lady of Loreto in Seville for his seminary studies. There he learned not only philosophy and theology but developed his musical talents. He was ordained in 1576, a ceremony his mother was unable to attend due to her poor health. He was then named Master of Ceremonies for the community. Still a lover of simplicity, Francis made a small cell for himself by the chapel of the friary, made of clay and reeds.