King's Highway 101, commonly referred to as Highway 101, is a provincially maintained highway in the Canadian province of Ontario. The highway connects Highway 17 west of Wawa with Highway 11 in Matheson before continuing east to the Ontario–Quebec border where it becomes Route 388. The highway forms one of the only connections between the two routes of the Trans-Canada Highway between Nipigon and Temagami, and crosses some of the most remote regions of Northern Ontario. Major junctions are located with Highway 129 near Chapleau and Highway 144 southwest of Timmins, though the distance between these junctions is significant.