His "Surgical Observations on the Constitutional Origin and Treatment of Local Diseases" (1809) – known as "My Book", from the great frequency with which he referred his patients to it, and to page 72 of it in particular, under that name – was one of the earliest popular works on medical science. So great was his zeal in encouraging patients to read the book that he earned the nickname ""Doctor My-Book"". He taught that local diseases were frequently the results of disordered states of the digestive organs, and were to be treated by purging and attention to diet. As a lecturer he was exceedingly attractive, and his success in teaching was largely attributable to the persuasiveness with which he enunciated his views. It has been said however, that the influence he exerted on those who attended his lectures was not beneficial in this respect, that his opinions were delivered so dogmatically, and all who differed from him were disparaged and denounced so contemptuously, as to repress instead of stimulating inquiry. The celebrity he attained in his practice was due not only to his great professional skill, but also in part to his eccentricity. He was very blunt with his patients, treating them often brusquely and sometimes even rudely. He resigned his position at St Bartholomew's Hospital in 1827, and died at his residence at Enfield on 20 April 1831.