The Pocket Athletic Conference was established in 1938 with nine founding schools: Cannelton, Chrisney, Lynnville, Mount Vernon, Owensville, Petersburg, Poseyville, Rockport, and Tell City. Seven of the nine original schools remain members in some form today. Cannelton left in 1971 and is now an independent. Mount Vernon left in 1959 to join the Southern Indiana Athletic Conference then a member of the Big Eight Conference before returning to the conference in 2020. All of the original members, all current members, and most of the new members are in counties along the western end of the Interstate 64 corridor within Indiana.