Title 42 Section 73 of the CFR addresses specific aspects of biosafety including Occupational safety and health, transportation of biohazardous materials and safety plans for laboratories using potential biohazards. While biocontainment, as defined in the Biosafety in Microbiological and Biomedical Laboratories and Primary Containment for Biohazards: Selection, Installation and Use of Biosafety Cabinets manuals available at the Centers for Disease Control and Prevention website much of the design, implementation and monitoring of protocols are left up to state and local authorities.