The Malankara Orthodox Syrian Church holds to miaphysitism, which holds that in the one person of Jesus Christ, divinity and humanity are united in one (μία, "mia") nature (φύσις – "physis") without separation, without confusion, without alteration and without mixing where Christ is consubstantial with God the Father. Around 500 bishops within the Patriarchates of Alexandria, Antioch and Jerusalem refused to accept the dyophysitism (two natures) doctrine decreed by the 4th ecumenical council, the Council of Chalcedon in 451, an incident that resulted in the first major split in the main body of the Christian Church. While the Oriental Orthodox churches rejected the Chalcedonian definition, the Catholic Church and the Eastern Orthodox Church accepted this council.