The 390th received a 2d DUC for a mission on 14 October 1943 when the group braved unrelenting assaults by enemy fighters to bomb the antifriction-bearing plants at Schweinfurt. Participating in the intensive Allied assault on the German aircraft industry during Big Week, 20–25 February 1944, the organization bombed aircraft factories, instrument plants and air parks. Other strategic missions included attacks on marshalling yards at Frankfurt, bridges at Cologne, oil facilities at Zeitz, factories at Mannheim, naval installations at Bremen and synthetic oil refineries at Merseburg.