He made his fastest opening to a season in 2001 by winning the 100 m for his club Belgrave Harriers at the European Clubs Cup with a meet record time of 10.12 s. At the Amateur Athletics Association (AAA) trials in Birmingham his run of 10.01 s was the fastest ever wind-legal time recorded in Britain by a British sprinter. Chambers ran with consistency in the summer of 2001: he won at the Seville Grand Prix in 10.01 s and finished third in ten seconds flat at the Athletissima meet. In the run up to the 2001 IAAF Edmonton World Championships Chambers compared his own performances to the British record holder: "I am very consistent in the 10.00s this year, and that bodes well for the Worlds. If you are running as fast as Linford Christie in his prime, it gives you a lot of confidence."