François was born in Nancy as the eldest of three children; early on in her schooling she gave evidence of great memory and a gift for writing. After six years in Catholic boarding school, where she met her future partner Marie-Claire Pichaud, she studied philosophy in Nancy and married, more or less for convenience: the two oldest children of this marriage were raised by their father, the youngest by François and her partner. Her partner is a painter, whose artistic sensitivities greatly influenced François, who embarked on a career as a writer. A turning moment was meeting poet René Char in the 1960s. François and Pichaud lived in Saumane-de-Vaucluse for twenty-five years before moving to Paris in 1985, amid health problems.