In late 2001, Simpson sang the song as part of MTV's "Spring Break" program, held in Cancún, Mexico. She later performed the song at The Monkey Club in Paris, France. "Irresistible" was sung during the 2001 "Dick Clark's New Year's Rockin' Eve", along with "A Little Bit". In 2002, Simpson sang "Irresistible" at Rockin' for the USA, a music special honoring the United States Armed Forces. In 2004, Simpson went out on her second headlining tour, the Reality Tour, to promote her third studio album "In This Skin" (2003). The tour, unlike the DreamChaser Tour, had no dance production. On the Houston stop of the North American leg of the tour, Simpson performed "Irresistible" at the end of the show, before singing "With You", a song from "In This Skin", as the encore. However, on the Ohio stop, she performed the song after "Underneath", another song from "In This Skin". Her performance was approved by Dustin J. Seibert of "The Cincinnati Enquirer", who wrote that "Simpson's reliance on her high-octane voice and bubbly personality set her apart from some of her pop counterparts."