PSHS is known for its active participation in national and international science, technology, and mathematics competitions such as Sipnayan, Kapnayan, MATHirang MATHibay, Metrobank-MTAP-DepEd Math Challenge, Philippine Mathematics, Physics, and Chemistry Olympiads, Australian Mathematics Competition and Australian Chemistry Quiz. Through private funding, students successfully reap awards in international competitions such as the Taiwan International Science and Engineering Fair, Intel International Science and Engineering Fair, International Math Olympiad, International Junior Science Olympiad, International Earth Science Olympiad, International Olympiad on Astronomy and Astrophysics, and International Physics Olympiad.