The Plano West Chamber Orchestra is made up of approximately 40 musicians. It has won 1st place in the Texas Music Educators Association (TMEA) Honor Orchestra competition (recognizing the top high school string orchestras in Texas) 5 consecutive times, in 2002, 2004, 2006, 2008, and 2010 (TMEA rules prohibit a school from entering the competition the year after it has won), along with several top-5 finishes from 2011-2015. The orchestra received the TMEA "Honor Orchestra" designation again in 2016 and 2019. The orchestra has also been featured on the Disney Channel series "Totally in Tune" which aired in 2001. In 2005, the orchestra won a Cappie Award for Outstanding Pit Orchestra in a musical for the school production of Les Misérables.