In a study from 2016, the authors investigated a set of 41 Y-SNPs in 1217 unrelated males from the five Brazilian geopolitical regions. A total of 22 haplogroups were detected in the whole Brazilian sample, revealing the three major continental origins of the current population, namely from America, Europe and Africa. The genetic differences observed among regions were, however, consistent with the colonization history of the country. The sample from the Northern region presented the highest Native American ancestry (8.4%), whereas the more pronounced African contribution could be observed in the Northeastern population (15.1%). The Central-Western and Southern samples showed the higher European contributions (95.7% and 93.6%, respectively). The Southeastern region presented significant European (86.1%) and African (12.0%) contributions. Portugal was estimated to be the main source of the male European lineages to Central-West, Southeast and South Brazil. The North and the Northeast showed the highest contribution from France and Italy, respectively. The highest migration rate from Lebanon was to the Central-Weast, whereas a significant migration from Germany was observed to the Central East, Southeast and South.