Peña Boulevard begins at an interchange with I-70 in Aurora as a northern continuation of Airport Boulevard. The first freeway interchange is at East 40th Avenue, which also provides traffic access to and from to Aurora's Airport Boulevard running to the south. Travelers leaving the airport use this exit for access to eastbound I-70 through the adjacent Airport Boulevard/I-70 interchange. Travelers inbound to the airport from I-70 East do not have access to the first interchange. Continuing north, the freeway leaves Aurora and passes into the Denver Gateway area, Aurora's Gateway Park development is adjacent. An interchange with Green Valley Ranch Boulevard provides access to the neighborhood of the same name. The East 56th Avenue interchange is the final exit along Peña Boulevard before it turns east near the Rocky Mountain Arsenal National Wildlife Refuge, and reaches the interchange with Tower Road, which serves several airport hotels.