Central Catholic's campus consists of three inter-connected buildings on a small plot of land off Hampshire Street in north Lawrence. The first of which is the oldest remaining part of the Auburn St. school known as the Memorial Gymnasium, known as the "Gym Building" (opened 1950). This building houses classrooms in a hallway known as "the Horseshoe" and the gym, along with a large performance stage. The second of which is the Hampshire Street building, known as the "Old Building" (opened 1969).