He learned that the chemists of the French Connection had moved clandestine labs for refining heroin from Marseilles to Sicily. At the end of 1980 he visited the United States and started to work with the U.S. Justice Department, resulting in “some of the biggest international law enforcement operations in history” such as the Pizza Connection. The inquiries extended to Turkey, an important stopover on the route of morphine base; to Switzerland, where bank secrecy laws facilitated money laundering; and to Naples where cigarette smuggling rings were being reconfigured as heroin operations. At the end of 1981, he finalised the Spatola case for trial, which enabled the prosecution to win 74 convictions, based on Falcone's “web of solid evidence, bank and travel records, seized heroin shipments, fingerprint and handwriting analyses, wiretapped conversations and firsthand testimony” that proved that “Sicily had replaced France as the principal gateway for refining and exporting heroin to the United States”.