Hamilton tried to operate for profit the already well-established Murray's Distribution Centre and Mill under the management of his cousin. Among other ventures, Hamilton became land wealthy, expropriating lands from subsistence Loyalist settlers who were incapable of settling their debts. Murray's distribution centre, later Hamilton's warehouse, and its location have long been a mystery. Hamilton's major profits were derived from transhipping supplies for the military and civic establishments from his Queenston enterprise, not from charitably supplying the subsistence Loyalist settlers. Hamilton lacked interest in social development and sold his business to Jesse Thompson before the turn of the 18th century.