The Lake Monroe and Orlando Railroad was organized in 1875 with a charter to build from the St. Johns River port of Sanford south to Orlando. The South Florida Railroad was incorporated on October 16, 1878, but was unable to obtain a charter until December 9, 1879, when it took over the charter of the Lake Monroe and Orlando, which was in danger of losing its land grants. The South Florida first ran on November 11, 1880, running the short distance between Sanford and Orlando. However the company had plans to continue to the Gulf of Mexico, reaching it at Tampa.