The dialogue spoken by the giant mutant Stan was inspired by a mentally handicapped character in the MTV show "How's Your News?", which Parker and Stone produced; according to Parker and Stone, the character could only say phrases like "Bubba chop, bubba chewy chomp", and both men took turns voicing mutant Stan to sound the same way. Isaac Hayes, who does the voice of Chef, recorded all his lines via phone from New York; Parker and Stone said they were nervous to ask him to repeat the line, "Now I know how all those white women felt", but he had no problem repeating it. The genetic mutations Dr. Mephesto creates, including the animals with multiple asses and the goldfish with bunny ears, were inspired by things Parker drew during high school.