After defeating No. 25 (12 seed) UTEP, 13 seed Murray State and No. 4 (1 seed) Syracuse, the No. 8 (ESPN)/No. 11 (AP) (5 seed) Butler men's team defeated No. 7 Kansas State, the 2 seed in the West, by a score of 63–56 to advance to their first Final Four. After beating the No. 12 (ESPN)/No. 13 (AP) (5 seed) Michigan State Spartans 52–50 in the national semifinals, Butler played in Indianapolis against the South Regional Champions, No. 3 (1 seed) Duke for the NCAA Division I National Championship. Butler lost what many call the most thrilling college basketball game in a generation, losing 61–59 in a game that came down to the final play. This is the farthest any team has reached in the tournament while a member of the Horizon League. Butler was the first Division I men's team to play in the Final Four in its hometown since UCLA in 1972, and the first of either sex since Texas played in the 1987 Women's Final Four on its home court.