Reviewing the Genesis version, "GamePro" assessed that the game successfully appeals to the TV show's preadolescent target audience. They criticized the limited music and absence of voices, but praised the cartoony and detailed graphics and the way the level design requires the player to make regular use of all three characters. They gave the Super NES version a negative review, citing overly simplistic and frustrating gameplay, though they did praise the graphics for their large and colorful sprites and background references to the TV show. Reviewing the Game Boy version, they criticized the slow-moving characters and trial-and-error gameplay, but approved of the graphics and audio and concluded, "The humor and spirit of the Animaniacs lives on in this handheld game."