He was handed the number nine shirt by manager Sam Allardyce at the beginning of the new Premier League campaign. Despite missing much of pre-season, Kalinić started the 2010–11 season well, scoring the only goal in Blackburn's opening day victory over Everton at Ewood Park on 14 August. On 28 December 2010, he netted his first brace in Blackburn colours in their 1–3 away win over West Bromwich Albion at The Hawthorns, though he was later sent off in this game. After Sam Allardyce was sacked as Blackburn manager, Kalinić fell out of favor with Blackburn's newly appointed manager Steve Kean.