Now in the town of Locke, NY 90 proceeds northwest past the southern terminus of Toll Gate Road (CR 54) before gaining the moniker of Water Street as the route enters the hamlet of Locke. The main west–east street through Locke, NY 90 junctions with NY 38 (Main Street). NY 90 makes a sharp bend to the southwest, keeping the Water Street until leaving the hamlet of Locke at Maple Avenue. Winding southwest out of Locke, NY 90 parallels Hemlock Creek past a junction with Bird Cemetery Road (CR 51). The route then continues southwest past Goodrich Hill Road (CR 160) and soon bends westward for a short distance.