Francesco Forgione was born to Grazio Mario Forgione (1860–1946) and Maria Giuseppa Di Nunzio (1859–1929) on May 25, 1887, in Pietrelcina, a town in the province of Benevento, in the Southern Italian region of Campania. His parents were peasant farmers. He was baptized in the nearby Santa Anna Chapel, which stands upon the walls of a castle. He later served as an altar boy in this same chapel. He had an older brother, Michele, and three younger sisters, Felicita, Pellegrina, and Grazia (who was later to become a Bridgettine nun). His parents had two other children who died in infancy. When he was baptized, he was given the name Francesco. He stated that by the time he was five years old, he had already made the decision to dedicate his entire life to God. He worked on the land up to the age of 10, looking after the small flock of sheep the family owned.