Anthony Giacalone gained national fame in the 1970s with the disappearance of Jimmy Hoffa. Prior to then, there had been growing tension between Hoffa and several Mafia members, who opposed his plans to return to prominence in the International Brotherhood of Teamsters. The latter included Giacalone, Anthony Provenzano and Giacalone's brother Vito. On July 30, 1975, Hoffa disappeared after he had gone out to a restaurant to meet Provenzano and Giacalone. Giacalone had not been near the restaurant that afternoon, though he was suspected of being involved in a conspiracy to murder Hoffa. Giacalone was later jailed for 10 years in 1976 for income tax fraud at FCI, Oxford, Wisconsin.