While remaining close to the Moor family (who had no other children and virtually "adopted" him as a son), eventually, Weitzel became engaged on another furlough home. On January 6, 1865, he married Louise Bogen, daughter of Peter Bogen, a prominent pork-packer and grower of Catawba grapes for winemaking. They would have three children, only one of whom survived infancy. Their first child was a stillborn son named Godfrey Weitzel, delivered on September 26, 1865. Their second child, Blanche Celeste Weitzel, was born on February 16, 1868, but contracted measles and died on April 5. Their third child, Irene Weitzel, born on April 11, 1876, lived until 1936 and left descendants.