Ulcerative colitis is "cured" if the large intestine is removed and the patient has the pouch created, as UC is only located in the colon, or large intestine. Crohn's disease can manifest in many different parts of the digestive tract, so the removal of the colon and creation of a pouch, while alleviating symptoms that occurred in the large intestine, does not eliminate the disease. The most common location for Crohn's disease to manifest is the last, or terminal portion, of the small intestine, also known as the ileum. If Crohn's disease patients received surgery for an ileo-anal pouch, the surgeons would eventually have to undo their work and create an ileostomy.