"They All Laughed" was the last theatrical film in which Hepburn played a lead role (she later starred in the television film "Love Among Thieves" and had a cameo role in Steven Spielberg's "Always"). According to an interview conducted by Wes Anderson in the DVD features for the film, director Bogdanovich claims Hepburn and Gazzara fell in love and had an affair while shooting "Bloodline" (1979). Though the affair was short-lived, it inspired the characters they each played in "They All Laughed".