The subchannel launched in the summer of 2006 as an affiliate of NBC-owned Spanish-language television network Telemundo since the Nashville market lacked a standalone Telemundo affiliate of its own. The second subchannel was branded as Telemundo Nashville. The subchannel went defunct on December 31, 2010, leaving Nashville with only one Spanish-language television station, WLLC-LP (Channel 42), the area’s Telefutura (now UniMás) outlet. (WLLC-LP has since added Univision as their primary affiliation on 42.1, with UniMás moving to 42.2.) The subchannel's spectrum would be used for purposes other than over-the-air broadcasting once the subchannel went dark.