The Japanese had been active on the seas and across the region for centuries, traveling for commercial, political, religious and other reasons. The 16th century, however, saw a dramatic increase in such travel and activity. The internal strife of the Sengoku period caused a great many people, primarily samurai, commoner merchants, and Christian refugees to seek their fortunes across the seas. Many of the samurai who fled Japan around this time were those who stood on the losing sides of various major conflicts; some were rōnin, some veterans of the Japanese invasions of Korea or of various other major conflicts. As Toyotomi Hideyoshi and later the Tokugawa shōguns issued repeated bans on Christianity, many fled the country; a significant portion of those settled in Catholic Manila.