In 1966, he appeared in the second series of "The Bed-Sit Girl". Derek Nimmo appeared on stage in many West End plays and starred in the musical "Charlie Girl", which contained a scene specially written to allow him to perform his party trick of wiggling his toes. He also became a regular panelist on the popular BBC radio show "Just a Minute", and had a chat show on BBC Television, "If It's Saturday, It Must Be Nimmo", from 24 October to 19 December 1970, though it was felt that he seemed less at ease as a chat show host. Having been away from television for some time, he made an appearance in the Australian television series "Neighbours" in 1990, playing Lord Ledgerwood alongside Madge and Harold Bishop.