Following the collapse of the NFL Europa franchise, Chambers made a second return to athletics in early 2008. Competing in the 60 m indoor final at the Birmingham Games in February 2008, he finished with a time of 6.60 s, setting a new meeting record. UK Athletics chief executive Niels de Vos initially banned Chambers from competing in the trials for the 2008 IAAF World Indoor Championships but, after the IAAF overruled the decision, Chambers won the event and selection. UK Athletics stated that committee was "unanimous in its desire not to select Dwain" but were forced to by the selection criteria, saying they would have preferred to send younger athletes eligible for the Olympics.