He made his Premier League debut for Aston Villa in an away match against Wigan Athletic at the DW Stadium on 25 January 2011 in a 2–1 win. However, on 12 February 2011, Makoun was sent off after receiving a straight red card for a tackle on Blackpool's DJ Campbell, as they drew 1–1. After a match, Makoun received a three match ban. Upon his return from suspension, Makoun spoken out, saying that he was shocked to believe the length of his suspension. Makoun made his return in a 0–1 defeat against Wolverhampton Wanderers on 19 March 2011. However, he began to find himself behind the pecking order in midfield position and never played for the club for the rest of the 2010–11 season. At the end of the 2010–11 season, Makoun made eight appearances for the side in all competitions.