In the fourteenth edition of the National Institute of Health report on carcinogens, the half-life time differences between chloroprene in air, water and soil were highlighted. In the air, chloroprene “reacts with photo-chemically generated hydroxyl radicals” and has a half-life of 18 hours. The smaller amounts that are removed by reaction with ozone have a half-life of 10 days. In streams, chloroprene is stated to volatilize quickly with a half-life of 3 hours. However, in bigger bodies of water such as a lake, the half-life of chloroprene is 4 days. Similar to its reaction with water, chloroprene on soil was cited to volatilize from the surface. However, the report remarked that chloroprene holds the potential to leach into groundwater supplies. Due to its volatility and extreme reactivity, the threat of chloroprene exists predominantly as an air pollutant and is not expected to bioaccumulate or persist in the environment according to the U.S EPA Toxicological Review of Chloroprene. However, the Centers for Disease Control and Prevention (CDC) states that chloroprene does, in fact, have the potential to persist in the environment. Nonetheless, the primary route of exposure for animals and humans is inhalation, but can be absorbed through the skin or indigestion.