Reed was also active in the political world. He was an organizer for Ronald Reagan's first campaign for governor of California in 1966. He helped finance Governor Reagan's first unsuccessful run for the presidency in 1968. Reed established a national network of political operatives and hired F. Clifton White, the noted political strategist, to guide the effort. Reagan lost to Richard Nixon. Reed managed Reagan's successful gubernatorial re-election campaign in 1970. In 1972, Reed performed as a national operative for the Nixon presidential re-election drive.