During the French and Indian War, Alice (Binnie Barnes) and Cora Munro (Heather Angel), the two daughters of Colonel Munro (Hugh Buckler), commander of a British fort, set out from Albany to join their father. They are escorted by Major Duncan Heyward (Henry Wilcoxon), who has loved Alice for a long time, and by the Huron Indian Magua (Bruce Cabot). Magua is secretly an enemy of the British. Magua betrays them, but they are rescued by a colonial scout named Hawkeye (Randolph Scott) and his friends, the last two members of the Mohican tribe, Chingachgook (Robert Barrat) and his son Uncas (Phillip Reed). On their way to the fort, Uncas falls in love with Cora, while Hawkeye and Alice are attracted to each other.