Injuries continued to bother Safin in 2006. Although Safin made appearances at the 2006 ATP Masters tournaments at Indian Wells, Miami, Monte Carlo, Rome and Hamburg, his ranking plummeted to as low as No. 104. He began to recover in time for the 2006 US Open, in which Safin defeated No. 4 David Nalbandian in a riveting second-round match. Safin then lost in the fourth round to No. 16 Tommy Haas, also in a fifth-set tiebreaker. Positive performances at the Thailand Open, where he was narrowly edged out by No. 7 seed, James Blake, and the Kremlin Cup in Moscow, the first all-Russian final at that event, losing to compatriot, Ukrainian-born Nikolay Davydenko, marked Safin's recovery. Despite the injury, Safin still posted seven wins against top ten players in 2006, fourth-most on the ATP tour behind just Federer (19), Nadal (10), and Blake (8).