Middle Eastern medicine preserved, systematized and developed the medical knowledge of classical antiquity, including the major traditions of Hippocrates, Galen and Dioscorides. During the post-classical era, Middle Eastern medicine was the most advanced in the world, integrating concepts of ancient Greek, Roman, Mesopotamian and Persian medicine as well as the ancient Indian tradition of Ayurveda, while making numerous advances and innovations. Islamic medicine, along with knowledge of classical medicine, was later adopted in the medieval medicine of Western Europe, after European physicians became familiar with Islamic medical authors during the Renaissance of the 12th century.