On 18 July 1957, the Wing suffered its first peacetime major accident. A KC-97G from the 380th Air Refueling Squadron with a crew of eight exploded and crashed into Lake Champlain when 2 of the 4 engines failed 3 minutes after take-off from Plattsburgh AFB at 9:28 p.m. During February 1959, the wing gained both the 820th Air Base Group and the 4020th USAF Hospital. Both of these units had previously been assigned to the 820th Air Division, located at Plattsburgh AFB. The 531st BS was activated and assigned to the 380th in May 1959. Later that year, on 7 August, another unit was attached to the Wing from the 820th AD, the 26th Air Refueling Squadron. The 531st was inactivated on 1 January 1962.