The neighborhood is close to two subway stops on the Market-Frankford Line, located at 34th and Market and 40th and Market. Powelton is also easily accessed by trolley: the route 10 trolley runs on 36th Street between the Ludlow Street portal and Lancaster Avenue, continuing west on Lancaster Avenue. Additionally, there are two underground trolley stops close to Powelton: 33rd and Market, serving all trolley lines, and 36th and Sansom, serving all lines except route 10. Bus route 31 runs through the neighborhood, traveling north on 33rd, Baring, and 35th, and south on 37th, Baring, and 34th. Route 43 runs east on Spring Garden Street and west on Haverford Avenue. The neighborhood is adjacent to 30th Street Station, which serves all Northeast Corridor trains, the New Jersey Transit Atlantic City Line, and all Regional Rail lines, as well as the Market-Frankford Line and the subway-surface trolley lines.