In the 2016 MLS Cup Final against Seattle, held at BMO Field on 10 December, Giovinco's performance was largely stifled by Seattle's heavy and aggressive defending, despite initially creating an early goalscoring chance for Altidore; throughout the match, he was fouled a total of six times and had several shots blocked. A scoring opportunity came in the 48th minute, but his shot was skewed wide of the near post. He was eventually substituted for Tosaint Ricketts in the 103rd minute, due to an apparent injury, and consequently, despite being the club's main penalty kick taker, was not used in the resulting shoot-out, which Toronto FC lost 5–4, following a 0–0 draw after extra-time. Regarding Giovinco's substitution, coach Greg Vanney stated in the post-match press conference: "He couldn't move. He looked at me. It's not like I take him off because I want to. I look at him and he gives me the sign that he can’t go any more and when he feels like he can’t go, he feels like he’s more of a liability to the group than anything. That’s the decision. It's not one that I generally want to make, but we had to."