Ramírez missed most of the Apertura 2010 season due to health problems, one was due to Orchitis which he was scheduled to be out 15 to 21 days. Orchitis prevented him to play the 2010 North American SuperLiga final against New England Revolution which Morelia won. He returned to action coming in for Ismael Pineda in the 55th minute in a 2–0 home loss to Club América. Ramírez also missed several matches due to a sports hernia. Ramírez returned to action in the 16th week in 1–0 away win over UANL, coming in the 63rd minute for Luis Gabriel Rey. Ramírez finished the Apertura 2010 season coming in as a substitute in a 3–3 draw against Puebla, Ramírez came in as a half time replacement for Luis Gabriel Rey but was sent off seven minutes later along with Puebla's Felipe Ayala after throwing punches, Morelia did not make the "liguilla" after ending in 12th place with 21 points.