In well-designed studies, the effect of false causality can be eliminated by assigning some people into a "treatment group" and some people into a "control group" at random, and giving the treatment group the treatment and not giving the control group the treatment. In the above example, a researcher might expose one group of people to chemical X and leave a second group unexposed. If the first group had higher cancer rates, the researcher knows that there is no third factor that affected whether a person was exposed because he controlled who was exposed or not, and he assigned people to the exposed and non-exposed groups at random. However, in many applications, actually doing an experiment in this way is either prohibitively expensive, infeasible, unethical, illegal, or downright impossible. For example, it is highly unlikely that an IRB would accept an experiment that involved intentionally exposing people to a dangerous substance in order to test its toxicity. The obvious ethical implications of such types of experiments limit researchers' ability to empirically test causation.