As in the 12th round, Pryor once again came out with a burst of energy in the 14th round after Panama Lewis broke another ammonia spirit under his nose and give him to drink water mixed with possibly antihistamine pills to have a longer lung capacity in the later rounds according to Luis Resto, another Panama Lewis fighter. That happen between the 13th and the 14th rounds, Panama Lewis gave Pryor to drink that mixed drink as early as the 2nd round, and this time Arguello could not answer it. Pryor battered Arguello around the ring for the first minute of the round, until a hard combination drove a staggering Arguello to the ropes, where Pryor proceeded to land a grisly series of almost twenty unanswered punches that nearly sent Arguello out of the ring. The proud Arguello refused to go down, until Referee Stanley Christodoulou of South Africa stepped in to stop the fight, at which point Arguello collapsed to the canvas. His cornermen rushed to his side, afraid that Arguello had been seriously hurt.