"Ladies and Gentlemen We Are Floating in Space" was released to widespread acclaim from music critics. "NME" critic Paul Moody hailed the album as a "seismic tour de force" and credited Jason Pierce for taking cues from his vast array of musical influences to create an "entirely new noise out of the wreckage", while "Melody Maker" praised it as "one mind-blowing perspective-fusing supernova of an album... that redefines notions of bittersweet and love-hate to the point where everyday emotions seem very small indeed." Roy Wilkinson of "Select" noted the album's more elaborate instrumentation and production styles compared to Spiritualized's previous work and called "Ladies and Gentlemen We Are Floating in Space" a "remarkable testimony to Pierce's vision". Steve Hochman of the "Los Angeles Times" named the album as "one of the most ambitious and striking sonic pastiches" of the year and said that it "recycles, refines and expands on the key elements" of "Lazer Guided Melodies" and "Pure Phase".