The insurance company Ag2r Prevoyance took over as the main sponsor in 2000. The team obtained further successes with Laurent Brochard, Jaan Kirsipuu and Jean-Patrick Nazon. In 2006, the team joined the UCI ProTour, following the signings of big cycling names Francisco Mancebo and Christophe Moreau. Fassa Bortolo's exit from the competition had freed a licence and AG2R was the only team left vying for the license, as Comunidad Valenciana voluntarily withdrew, while the proposed new team of former Fassa Bortolo sporting director Giancarlo Ferretti turned out to be without financial backing. Ag2r obtained success in the 2006 Tour de France with a stage win by Sylvain Calzati, and a day in the yellow jersey as leader of the general classification by Cyril Dessel.