More than anything else the controversies on the Lord's Supper embittered the last years of his life. The renewal of this dispute was due to the victory in the Reformed Church of the Calvinistic doctrine and its influence upon Germany. To its tenets Melanchthon never gave his assent, nor did he use its characteristic formulas. The personal presence and self-impartation of Christ in the Lord's Supper were especially important for Melanchthon; but he did not definitely state how body and blood are related to this. Although rejecting the physical act of mastication, he nevertheless assumed the real presence of the body of Christ and therefore also a real self-impartation. Melanchthon differed from John Calvin also in emphasizing the relation of the Lord's Supper to justification.