The Washington metropolitan area has a significant biotechnology industry; companies with a major presence in the region as of 2011 include Merck, Pfizer, Human Genome Sciences, Martek Biosciences, and Qiagen. Additionally, many biotechnology companies such as United Therapeutics, Novavax, Emergent BioSolutions, Parabon NanoLabs and MedImmune have headquarters in the region. The area is also home to branch offices of many contract research organizations. Firms with a presence in the area include Covance, IQVIA, Charles River Laboratories, and ICON plc. The area's medical research is driven by government and non-profit health institutions, such as the Howard Hughes Medical Institute, J. Craig Venter Institute, and the National Institutes of Health.