In the city of Horse Cave, US 31W intersects KY 218; the Dixie Highway then continues on to Munfordville before crossing I-65 for a fifth time at the interstate's exit 65 interchange, and paralleling it closely to the west and later, the east. Between Upton and Sonora, it crosses over I-65 for a sixth time. In Elizabethtown, US 31W intersects with the Wendell H. Ford Western Kentucky Parkway before crossing I-65 for a seventh time. The route continue through the heart of Elizabethtown, intersecting US 62, before it goes on to enter Radcliff. It also passes through Fort Knox near Radcliff, within sight of the United States Bullion Depository. US 31W overlaps with US 60 from Muldraugh to Louisville, paralleling the Ohio River briefly before an interchange with I-264 (Watterson Expressway) in Louisville. US 31W continues as a one-way pair consisting of 22nd and Dr. W. J. Hodges streets, and later Main and Market streets in downtown Louisville. At 2nd Street, US 31W ends at US 31E, and the two routes continue north as US 31 before crossing the Ohio River into Jeffersonville, in Clark County, Indiana.