Chambers was discovered by a modelling scout on the Metro and went on to star in ad campaigns for Calvin Klein's fragrance range. He worked throughout Europe, Japan, and the United States for Calvin Klein, Armani, and Dolce & Gabbana. After deciding on an acting career, he moved to New York City in the early 1990s, where he studied at the HB Studio. Studios and Ron Stetson Studios for four years. His first major acting role came in the music video "Ants Marching" by Dave Matthews Band in 1995. He went on to land a few television roles, including a contract role as the original Nicholas Hudson in the NBC soap opera "Another World", and "New York Undercover". In 1998, he was cast as series regular in the short-lived CBS primetime soap opera "Four Corners". Chambers also appeared in several television movies, such as "Harvest of Fire", "Rose Hill", and "Seasons of Love".