"Scarborough" arrived at the Cape of Good Hope on 13 April 1790, and spent 16 days there, taking on provisions, and eight male convicts from , which had been wrecked after striking an iceberg. She and "Neptune" parted from "Surprize" in heavy weather and arrived at Port Jackson on 28 June - 160 days out from England. During the voyage 68 convicts died and 96 (37%) were sick when landed. After landing, a total of 124 convicts who had arrived in Port Jackson succumbed to disease. She also brought with her two officers and 38 soldiers.