After leading Cincinnati to six straight wins to begin the 1988 season, on October 16, 1988, he set a single game team record throwing 5 interceptions in a 27–21 loss to the New England Patriots. The team finished the season 12–4 with the highest scoring offense in the NFL, securing the organization's fifth AFC Central division title. He finished the season as the NFL's top rated passer. Cincinnati defeated Seattle and then Buffalo in the playoffs to reach Super Bowl XXIII, their second appearance in a Super Bowl, a rematch with the San Francisco 49ers. In the game, Bengals cornerback Lewis Billups dropped a sure interception in the end zone which would have sealed a Cincinnati win. The San Francisco 49ers, led by future Hall of Fame quarterback Joe Montana, marched 92 yards on their last drive and scored on a touchdown pass to receiver John Taylor with 34 seconds remaining in the game. A last-ditch pass by Esiason to wide receiver Cris Collinsworth was broken up, resulting in a 20–16 loss for the Bengals, their second close loss to the 49ers in a Super Bowl.