In 2005, Santino participated as a contestant on the second season of the Bravo reality show "Project Runway", producing mixed results on the show. He won two challenges and was among the top three designs three more times. However, Rice was among the bottom two scores for four challenges. Ultimately, he lasted throughout the season and was one of three finalists selected to show at Olympus Fashion Week in New York City. He finished in third place, behind Daniel Vosovic and Chloe Dao.