The film's plot combines several elements from these original films. Starrbooty (RuPaul) is in the middle of a major karate fight when she receives a phone call informing her that her adopted niece Cornisha has been kidnapped. With the help of fellow crime fighter Agent Page Turner, Starrbooty learns that her nemesis Annaka Manners is using her billion-dollar cosmetics company as a front for kidnapping prostitutes and selling their organs on the black market. Starrbooty also discovers that Annaka is actually her long-lost sister, making Cornisha Annaka's daughter.