Von Wiegand's first of more than 21 solo exhibitions was at the Rose Fried Gallery in New York, 1942. She participated in 35 major group exhibitions in the United States, Europe and Far East, including Peggy Guggenheim's 1945 Women's Show at the Art of this Century Gallery in New York. She received the first prize at Cranbook Academy of Art Religious Art Exhibition, Bloomfield Hills Michigan (1969). In 1980, she was elected to the American Academy of Arts and Letters. In 1974, Weigand had a retrospective showing of her work at the Noah Goldowsky Gallery in New York.