After leaving the Brooklyn area, the road returns to a rural environment as it cuts through agricultural fields. Before passing through Tipton, M-50 passes the entrance to Hidden Lake Gardens, a botanical garden and arboretum operated by Michigan State University. After passing Hidden Lake, the road intersects M-52 and continues into Tecumseh. Known as Chicago Boulevard, the road serves as the main route through the city. After leaving Tecumseh, the highway passes through the communities of Ridgeway and Britton before leaving Lenawee County.