As a result of the reactions to the 1990 article and its frequent citation by proponents of HGH as an anti-aging agent, in 2003 the "New England Journal of Medicine" published two articles that strongly and clearly stated that there was insufficient medical and scientific evidence to support use of HGH as anti-aging drug. One article was written by the "Journal"'s then-editor in chief, Jeffrey M. Drazen, M.D. and was entitled, "Inappropriate Advertising of Dietary Supplements". It focused mostly on the advertising of dietary supplements. The other article was written by the editor-in-chief at the time the 1990 article was published, Mary Lee Vance, M.D., and was entitled, "Can Growth Hormone Prevent Aging?"; it focused more on the medical issues around whether there was sufficient evidence to use HGH as an anti-aging agent.