Bettega won the Serie A title with Juventus yet again during the 1980–81 season, but did not feature extensively in Juventus's victorious defense of their Serie A campaign during the 1981–82 season, as he suffered knee ligament damage in a collision with an opposing goalkeeper during a 1981 European Cup match against Anderlecht. After finally regaining full fitness, he took to the pitch for the 1982–83 season, which would be his final season with the club. He retired from playing in Europe after Juventus lost the 1983 European Cup Final against Hamburg in Athens.