A few years after hearing her speak at an ADL function, television producer Walt Framer hired Myerson for the 1950s game show "The Big Payoff". She was the "Lady in Mink" modeling the grand prize mink coat, and introducing guests and prizes, throughout the 1951 to 1959 network run of the program. Recognized for her wit and hard work, in 1954 Myerson was a panelist on the game show "The Name's the Same" and from 1958 through 1967 a panelist on "I've Got a Secret". She regularly substituted for Dave Garroway on the "Today Show". She was also a host of the television broadcast of the Miss America pageant from 1954 to 1968.