Her recording career began in 1921. Over the next decade she recorded for a number of labels, including Edison, Columbia, Victor, Okeh, Gennett, and Brunswick. She occasionally recorded for the subsidiary labels of some of these companies under various pseudonyms. These included Gloria Geer, Mamie Lee, Sadie Green, Betty Brown, Nancy Foster, Marion Ross, Glory Clarke, Angelina Marco, and Gertrude Dwyer. De Leath had a highly versatile range of styles, and as material required could adapt as a serious balladeer, playful girl, vampish coquette, or vaudeville comedian.