The film is based on the story of Erzsébet Bathory, a Hungarian countess in the 16th and 17th centuries. Her story takes place in a part of the Kingdom of Hungary that is now Slovakia. In this retelling, the Countess is a healer who conducts medical experiments and rudimentary autopsies in a "hospital" beneath her castle. She forms a relationship with a reputed witch, Darvulia, who saves her from poisoning. The witch promises Erzsebet a son and eternal beauty. In return, Erzsebet must sacrifice both love and her reputation. Darvulia becomes Erzsebet's companion. Meanwhile, maidens in the area have been dying of seemingly unrelated causes, and Erzsebet is seen bathing in a large tub of red liquid as the girls' now-mutilated corpses are buried nearby. Two monks later conclude that the water is not blood but is simply colored red by herbs.