John Mitchell was not a professional geographer or map-maker. Son of a wealthy Virginian family in Lancaster County, on Virginia's Northern Neck, he had been educated at Edinburgh University, Scotland; this education included the first two years of the three-year medical program. Returning to coastal Virginia, he practiced as a physician and studied the local botany. Ill health forced Mitchell and his wife to leave Virginia for London in 1746. There, he served as a consultant on exotic plants to noblemen interested in gardens. Also, it was there that Mitchell would make his famous map. Map historians have understandably been interested in why a physician and botanist who had shown no previous interest in map making should make such a large and detailed map.