These phenomena brought Ossana to the attention of Mantua's ruling family. Most notably, she was sought by Francesco II Gonzaga and his wife, Isabella d'Este, as both a spiritual guide and a counselor on matters of state. She frequently foretold correctly events which later came to pass, and gained the reputation of a seer. When she died in Mantua on 18 June 1505, all the members of the nobility and clergy attended her funeral, as her body was taken in procession to the Church of St. Dominic, where it was enshrined. Later her remains were transferred to the Cathedral of St. Peter, where they are still venerated.