Mewtwo is featured in the film "" as the main antagonist. Unlike in the games, it is shown to be the creation of the criminal organization Team Rocket, and is referred to as a clone instead of a genetically modified mammal. After Mewtwo destroys the laboratory where it was born, Team Rocket's leader, Giovanni, convinces Mewtwo he can help it control its powers, instead using Mewtwo as a weapon. After escaping Giovanni, Mewtwo questions the reason for its existence and declares revenge on its creators. To this end, it lures several Pokémon trainers, among them protagonist Ash Ketchum, to its island in order to clone their Pokémon. Once it does so, Mewtwo forces the originals to battle their clones in an effort to determine which set is superior, while Mewtwo faces its own genetic relative, Mew. Ash sacrifices himself to stop the fighting, though he is later revived from tears shed by both the originals and clones because of his sacrifice.