On 21 December 2000, HLS was dropped from the New York Stock Exchange because its market capitalization had fallen below NYSE limits, and on 29 March 2001, HLS lost both of its market makers and its place on the London Stock Exchange. Shortly after this, HLS moved its headquarters to the United States, incorporating as Life Sciences Research (LSR), and secured a $15m loan from investment bank Stephens, Inc, its largest shareholder. In September 2005, after the firebombing of the homes of a Canadian brokerage employee and a British pharmaceutical executive, the New York Stock Exchange asked LSR to delay moving its listing from the OTC Bulletin Board to the main exchange. LSR has since transferred its listing to the NYSE Arca electronic exchange. HLS is no longer a publicly traded company after being bought by CEO Andrew Baker.