Together, Roy Vagelos and his wife Diana Vagelos donated over $15 million to the University of Pennsylvania to create the Roy and Diana Vagelos Laboratories. These funds also made possible the founding the Vagelos Scholars Program in Molecular Life Sciences, an intensive program offered to University of Pennsylvania freshmen. In addition, they donated funds to launch the Vagelos Program in Life Sciences and Management, a joint program between the Wharton School at the University of Pennsylvania and its College of Arts and Sciences. Later, they founded the Vagelos Integrated Program in Energy Research, supporting the necessity of energy research.