On March 16, Liuzzo took part in a protest at Wayne State. She then called her husband to tell him she would be traveling to Selma after hearing the Rev Dr. Martin Luther King Jr. call for people of all faiths to come and help, saying that the struggle "was everybody's fight." Leaving her children in the care of family and friends, she contacted the Southern Christian Leadership Conference who took her on and tasked her with delivering aid to various locations, welcoming and recruiting volunteers and transporting volunteers and marchers to and from airports, bus terminals, and train stations, for which she volunteered the use of her car, a 1963 Oldsmobile.