A 2007 review on the use of human growth hormone as an anti-aging treatment in healthy elderly people published in the "Annals of Internal Medicine" concluded the risks of HGH significantly outweigh the benefits, noted soft tissue edema as a common side effect and found no evidence that the hormone prolongs life. "ABC News" interviewed Hau Liu of Stanford University and lead author of the paper, who stated that people are paying thousands of dollars a year for a treatment that has not been proved to be beneficial and has many side effects. "ABC News" also reported that the A4A disputed the conclusions of this review, quoting from an A4A statement which maintained that growth hormone supplementation is beneficial in healthy adults and which described arguments against the use of the hormone as a "heinous act of malpractice".