Probably Le Jeune's most famous sacred work is his "Dodécacorde", a series of twelve psalm settings which he published in La Rochelle in 1598. Each of the psalms is set in a different one of the twelve modes as given by Zarlino. Some of his psalm settings are for large forces: for example he uses sixteen voices in his setting of Psalm 52. Published posthumously was a collection of all 150 psalms, "Les 150 pseaumes", for four and five voices; some of these were extremely popular, and were reprinted in several European countries throughout the 17th century.