Straylight Run shifted away from the emo sound of Taking Back Sunday, transitioning into an indie rock sound. Though "Straylight Run" retains the introspective lyricism commonly found in emo, it has more of an emphasis on a piano-based sound. The inclusion of synth parts and male–female vocal dynamics drew comparisons to the Anniversary and Bright Eyes. Michelle Nolan sings lead vocals on "Tool Sheds and Hot Tubs" and "Now It's Done", alongside providing backing vocals throughout the rest of the album.