As of October 2020, review aggregation website Rotten Tomatoes gave the film a score of 69% based on 177 reviews, with an average score of 6.23/10 and the consensus: ""Snakes on a Plane" lives up to its title, featuring snakes on a plane. It isn't perfect, but then again, it doesn't need to be." As of October 2020, Metacritic, which uses a weighted average rating system, the film earned 58/100 score based on 31 reviews, indicating "mixed or average reviews". Reviewers reported audiences cheering, applauding, and engaging in "call and response", noting that audience participation was an important part of the film's appeal.