The founder of the dynasty, William Keswick was born in 1834, in Dumfriesshire in the Scottish Lowlands. His grandmother, Jean Jardine Johnstone was an older sister of Dr. William Jardine, the founder of Jardine Matheson & Company His father Thomas Keswick had married Margaret Johnstone, Jardine's niece and daughter of Jean, and entered the Jardine business. The company operated as opium traders and had a major influence in the First and Second Opium Wars although the company stopped this trading in 1870 to pursue a broad range of other trading interests including shipping, railways, textiles and property development.