In his first title defense, Saad Muhammad met former world champion John Conteh in Atlantic City. He retained the world title with a 15-round decision. The decision, however, was voided and a rematch ordered because Muhammad's cornermen used an illegal substance to stop the bleeding from a cut. Muhammad retained the crown with a knockout in round four in the second bout. After defeating Louis Pergaud, he and López met again, this time, with the world title on the line. Their rematch has also been shown by ESPN's "classic" network several times, it was the "fight of the year" for 1980, according to Ring Magazine, and is still written about by boxing aficionados. Saad Muhammad was hit with 20 "unanswered" blows in round eight, but he recovered and dropped López five times en route to a 14th-round knockout win. “This was my toughest fight,” said Saad Muhammad of the fight, which some consider the closest López ever came to a world title.