In 2000s, Belafonte made a number of limited screen appearances, guest starring in an episode of "The District" and "Nip/Tuck". In December 2015, it was announced that Belafonte would take over the role of Mayor Janice Lomax from Saidah Arrika Ekulona on January 19, 2016, on the ABC daytime soap opera "General Hospital". She made her last appearance on December 20, 2017. In 2019, she began appearing in a recurring role as Julia in the Apple TV+ drama series "The Morning Show". Later that year, she took the recurring role as Ebony Obsidian' character' mother in the BET comedy-drama series, "Sistas".