Wylie East High School was opened for the 2007–2008 school year. The school initially served solely ninth grade students. Wylie East became a 9-12 school with the Class of 2012 being the first class to graduate after the district voted to have multiple 9-12 campuses in January 2008. Wylie East began the 2009–2010 school year with freshmen and sophomores. Wylie ISD serves most of the city of Wylie, including the city of St. Paul, a portion of the city of Murphy, and the Collin County portion of the city of Sachse. Enrollment has grown to just over 10,000 students with more than 2685 full-time employees.