The Huntington Heroes made their debut on March 11, 2006 in front of 3,100 fans at the Veterans Memorial Fieldhouse with a 62–13 victory over the Miami Valley Silverbacks. Following their first road win the following week at Johnstown, the Heroes suffered the franchise's first defeat at home on March 25, 2006 to the Erie Freeze. The Heroes got their revenge two weeks later by defeating the Freeze in Erie, 55–33, handing the Freeze their first regular season loss since their inception and standing as the Heroes' first signature win.