Putting in at the Atlantic Basin Iron Works again in June, the ship was renamed USAHS "Shamrock" in August 1943. With the conversion complete, the new hospital ship left New York in September for Gibraltar and the Mediterranean where she operated locally, calling often at Oran, Palermo, the southern beaches of France, Bizerte, and Naples. By mid-February 1944, "Shamrock" had transported 11,989 patients before departing Gibraltar for Charleston (via Bermuda), where she arrived in early March. After undergoing some repairs and alterations at Charleston, "Shamrock" sailed again for Gibraltar for another tour of duty in the Mediterranean area from May to September. After transporting over 6,000 patients during this mission, she returned via Horta, Azores, to Charleston in late September.