While on his mission to locate the Xindi, Archer is briefly into a member of the extinct Loque'eque by a mutagenic virus. Later, he is infected by subspace parasites, creating an in which the "Enterprise"'s mission fails and the Xindi succeed in destroying Earth (although the nature of these parasites mean that this timeline is erased when Phlox's cure for Archer erases the parasites themselves from history). With the help of , Archer, along with T'Pol, to the year 2004 to prevent the release of a Xindi-Reptilian bio-weapon.