A 13-episode anime television series adaptation of "Maria-sama ga Miteru" aired in Japan between January 7 and March 31, 2004 on TV Tokyo. Produced by Studio Deen and directed by Yukihiro Matsushita, the screenplay was written by Reiko Yoshida, and Akira Matsushima based the character design used in the anime on Reine Hibiki's original designs. The art director for the series is Nobuto Sakamoto. The sound director is Yoshikazu Iwanami, and the soundtrack is composed by Mikiya Katakura. The series was later released by Geneon to seven VHS and DVD compilation volumes from April to October 2004.