There were two major schools of skepticism in the ancient Greek and Roman world. The first was Pyrrhonism, founded by Pyrrho of Elis (c. 360–270 BCE). The second was Academic Skepticism, so-called because its two leading defenders, Arcesilaus (c. 315–240 BCE) who initiated the philosophy, and Carneades (c. 217–128 BCE), the philosophy's most famous proponent, were heads of Plato's Academy. Pyrrhonism's aims are psychological. It urges suspension of judgment ("epoche") to achieve mental tranquility ("ataraxia"). The Academic Skeptics denied that knowledge is possible ("acatalepsy"). The Academic Skeptics claimed that some beliefs are more reasonable or probable than others, whereas Pyrrhonian skeptics argue that equally compelling arguments can be given for or against any disputed view. Nearly all the writings of the ancient skeptics are now lost. Most of what we know about ancient skepticism is from Sextus Empiricus, a Pyrrhonian skeptic who lived in the second or third century CE. His works contain a lucid summary of stock skeptical arguments.