US 223 passes out of flat farmlands into the Irish Hills region as the highway runs northeast of Manitou Beach as the roadway rounds the northern shore of Devils Lake. The Irish Hills region has gently rolling hills that transition to forests from farms. Southeast of Somerset, US 223 meets US 127 and ends. The entire highway in both Ohio and Michigan is listed on the National Highway System, a system of highways important to the nation's economy, defense, and mobility.