The American Academy of Anti-Aging Medicine was formed following a 1990 study on human growth hormone (hGH) that was published in the "New England Journal of Medicine". The study was performed by Daniel Rudman and colleagues at the Medical College of Wisconsin. Rudman had treated twelve men over 60 years of age with human growth hormone; after six months, these men had an increase in lean body mass and a decrease in adipose tissue mass when compared with a group of nine men who did not receive hormone. Members of the anti-aging movement have interpreted these results to support a role for growth hormone in slowing or reversing aging. A review in "The Journal of Urology" noted that this promotion of growth hormone as an anti-aging remedy is "arguably similar" to ideas that date back to the late 19th century, when the physiologist Charles-Édouard Brown-Séquard advocated rejuvenating hormone products prepared from animal testicles and stated that "the injections have taken 30 years off my life".