The fourth section, with orange page borders, includes the actual response guides. Each of the 62 guides provides safety recommendations and directions on how to proceed during the initial response phase (first thirty minutes) of the incident. It includes "health" and "fire or explosion" potential hazard information (with the more dangerous hazard listed first). For example, "the material gives off irritating vapors, easily ignited by heat, reactive with water"; "highly toxic, may be fatal if inhaled, swallowed or absorbed through skin"; etc.