A number of inmates are being transferred to a new supermax prison, including mass murderer William "Billy Bedlam" Bedford, serial rapist John "Johnny 23" Baca, Black Guerrilla Family member Nathan "Diamond Dog" Jones, and criminal mastermind Cyrus "The Virus" Grissom. After taking off, inmate Joe "Pinball" Parker sets Cochise on fire as a distraction and releases Grissom and Diamond Dog, who lead the takeover of the plane. The hijacking inmates plot to land at Carson Airport as scheduled, pick up and transfer other prisoners, and then fly to a non-extradition country. Sims tries to retake control but Grissom kills him. Poe and Grissom also foil Johnny 23's rape attempts on the plane's only female guard, Sally Bishop, due to Grissom's vocal hatred of rapists.