On 3 May 2010, she married Densign White, a former Olympic judo athlete, at St. Paul's Cathedral in London. Her bridesmaids were her fellow Olympic teammates Sharron Davies, Kelly Holmes and Christine Ohuruogu. Sanderson unsuccessfully received In vitro fertilisation treatment three times before she was 50. In 2013, she and White started fostering four-month old twins, Cassius and Ruby Mae, and the couple adopted the twins the following year, when Sanderson was aged 58. Her nephew, Dion Sanderson, is a footballer who made his debut for Wolverhampton Wanderers in October 2019.