In March 2000, Guice became the artist on "Birds of Prey" for issues #15 to #34. In addition, Guice drew a "Robin and Oracle" story in "Batman: Gotham City Secret Files and Origins" and the "Universe X Spidey" one-shot, from Marvel. After his run on "Birds of Prey", Guice left DC Comics and moved to Tampa, Florida to work for CrossGen. He was brought in to launch "Ruse" with writer Mark Waid, in November 2001. Effectively a Victorian steampunk detective story, although set on an analogue of Earth in the far-distant future, and part of CrossGen's 'Sigilverse'. Guice continued as the penciller of "Ruse" until its cancellation with #26 (January 2004). Guice resigned from CrossGen "just prior to the layoffs" and before the remaining staff were released from "exclusivity status".