On the east side of the interchange, Illinois 22 enters Bannockburn as it passes near Trinity International University as well as some upper class real estate areas. The road next approaches the at-grade Milwaukee District/North Line tracks and major junction with Illinois Route 43 (Waukegan Road) while passing a shopping area on the southeast corner of that intersection. It then arrives in the last city on its journey, Highland Park, where it heads near the Prairie Wolf Slough Forest Preserve. Shortly after, it nears its end as it goes under the grade separated Union Pacific/North Line tracks and a pedestrian crossing before terminating at the well traveled, at-grade intersection of U.S. Route 41 (Skokie Highway);