Nebraska Highway 92 begins at the Wyoming border west of Lyman and after a brief turn south, heads east passing around the north side of Scotts Bluff National Monument, crosses the North Platte River for the first of three times, and enters the town of Scottsbluff. Starting in Scottsbluff, N-92, U.S. 26, and the North Platte River form a three-way braid, crisscrossing one another several times for until Lewellen. At Scottsbluff, it overlaps U.S. 26 and Nebraska Highway 71, crossing the North Platte River again to its south side, to Gering, where it then turns to the east-southeast, following the route of the Oregon Trail, paralleling the North Platte River and U.S. 26 on the other side of the river. Near Chimney Rock National Historic Site, it overlaps U.S. 26 again until Bridgeport. After a brief concurrency with U.S. 385, it goes southeast until it crosses the North Platte for the third time just before Broadwater. It then again overlaps U.S. 26 a third time from there until Lewellen, where it separates to go through the resort communities along the north shore of Lake McConaughy until it meets Nebraska Highway 61.