The Countess Granville died on 7 October 1745, leaving one daughter Sophia Carteret, who married William Petty, 2nd Earl of Shelburne, later 1st Marquess of Lansdowne. Granville's second marriage may have done something to increase his reputation for eccentricity. In February 1746 he allowed himself to be entrapped by the intrigues of the Pelhams into accepting the secretaryship, but resigned within forty-eight hours. In June 1751 he became president of the council, and was still liked and trusted by the King, but his share in government did not go beyond giving advice, and endeavouring to forward ministerial arrangements. In 1756 he was asked by Newcastle to become Prime Minister as the alternative to Pitt, but having perfectly understood why the offer was made, declined and supported Pitt. When in October 1761 Pitt, who had information of the signing of the "Family Compact" wished to declare war on Spain, and declared his intention to resign unless his advice was accepted, Granville replied that "the opinion of the majority (of the Cabinet) must decide". He spoke in complimentary terms of Pitt but resisted his claim to be considered as a "sole minister" or Prime Minister.