Reaching Lyon, the most populous city on its course, the Rhône receives its biggest tributary, the Saône, with a flow of , compared to the Rhône's at this point. From this confluence, the Rhône follows a southward course. Along the Rhône Valley, it is joined on the right (western) bank by the rivers Eyrieux, Ardèche, Cèze, and Gardon coming from the Cévennes mountains; and on the left bank by the rivers Isère, (with an average discharge of ), Drôme, Ouvèze, and Durance () from the Alps.