While he recognised the role of the germ theory of disease, defective organs and/or tissue, and other known and demonstrable sources of disease, Bach wondered how exposure to a pathogen could make one person sick, while another was unaffected, when to all appearances and analysis they were in equal states of health. He postulated that illness was the result of a conflict between the purposes of the soul and the personality's actions and outlooks. This internal war, according to Bach, leads to emotional imbalances and energetic blockage, which causes a lack of harmony, thus leading to physical diseases. Bach's remedies focus on treatment of the patient's personality, which he believed to be the ultimate root cause of disease.