After some years of professional activity, Linacre devoted himself to the study of theology and the duties of the priesthood. Around 1509, he received priest's orders as the rector of Merstham, Kent. Numerous ecclesiastical positions followed, finalising with him obtaining the rectorship of Wigan in 1520, which he held until his death in 1524. His clerical benefices, included the Precentorship of York Minster. His ordination was connected with his retirement from active life. Literary labours, and the cares of the foundation which owed its existence chiefly to him, the Royal College of Physicians, occupied Linacre's remaining years.