Andretti ran his first night race at Homestead-Miami Speedway, the first race of the 2008 season, with a 2nd-place finish behind Scott Dixon. He also led the most laps of the race – leading 85 – and received an additional three points. At St. Petersburg, Andretti snapped a half-shaft on his car trying to leave the pits, causing him to retire. In the third race of the season at Motegi, Japan, Andretti spun out on the first lap of the race. At the 2008 Indianapolis 500, Andretti finished third, after leading several laps. During the race, he passed teammate, Tony Kanaan, who then crashed into the wall, blaming Andretti.