SR 806 begins at a divided intersection with US 441 and SR 7) in the outskirts of Delray Beach near the Arthur R. Marshall Loxahatchee National Wildlife Refuge. SR 806 heads eastward along West Atlantic Avenue, a four-lane divided highway but quickly becomes two lanes and enters a small commercial district. The progression of the highway continues for a distance along West Atlantic Avenue, intersecting with several local streets and passing through some large groves and fields. After the intersection with Starkey Road, SR 806 divides back into four lanes, as it enters an interchange with Florida's Turnpike (unsigned SR 91). West Atlantic Avenue first intersects with the entranceway and exit ramp from the turnpike southbound and continues eastward over a stream. After passing under the eight lanes of the Turnpike, SR 806 intersects with the ramp to the northbound lanes. After leaving the large interchange with the turnpike, the highway continues eastward along the country clubs in Delray Beach, beginning with an intersection to the Lexington Club on the eastbound lanes. After that, State Road 806 continues, passing Eagle Point and soon intersecting with Hagen Ranch Road at a traffic light. The route then passes Kings Point Country Club and to the south of the Villages of Oriole, where the highway continues as six lanes, turning southeastward until intersecting with Jog Road (the northern continuation of SR 845) in Delray Beach.