Notre Dame of Maryland's campus is located on the main commercial/business and cultural street leading north to the formerly rural, now suburban Baltimore County from downtown Baltimore to the northern reaches of the City, North Charles Street. NDMU is situated between the wealthy residential neighborhoods from the early 20th Century of Homeland and Guilford, just north of the cross-town, Cold Spring Lane, and adjacent to the Evergreen campus of Loyola University Maryland (formerly Loyola College) to the south (occupied since 1922). It borders to the south, the historic landmark Greek Revival styled mansion of the Garrett family.