Bisson's first major role was in the CBC's critically acclaimed 1984 movie of the week "Hockey Night", alongside Megan Follows and Rick Moranis. He starred in the Canadian television series "Learning the Ropes" from 1988–89. From 1994–97, he starred in the syndicated action series "High Tide", co-starring Rick Springfield. He moved back from Los Angeles to Vancouver, British Columbia in 1998 when he was cast as the lead in CBC'S "Nothing Too Good for a Cowboy". From 2000–04, he had a recurring role as attorney Brian Tedrow on the Showtime drama "Soul Food".