In Marvel's Civil War miniseries and crossover event, Reed Richards is one of the leading figures, along with Iron Man, on the side which is in favor of the Superhuman Registration Act. He speculates that this will lead to conflict with his wife, which came true in issue #4 of the miniseries when a clone of Thor, created by him and Tony Stark, went out of control and killed Goliath and nearly killed all the rest of the Secret Avengers until Sue Storm stepped in and saved them. Soon after, Sue left Reed, along with Johnny, to join the Secret Avengers in hopes that it would drive Reed to end the conflict quickly.