The route heads through farmland before passing residences and intersecting the western terminus of MD 317 (Burrsville Road) in Oil City. Past MD 317, the road continues through mostly wooded areas with some residences and farmland. It reaches the town of Greensboro, where MD 313 intersects MD 314 (Whiteleysburg Road). The route crosses the Choptank River past MD 314 and continues to the intersection with the eastern terminus of MD 480 (Ridgely Road) just north of Greensboro. The road continues north through agricultural areas before entering Goldsboro, where the route becomes Old Town Road. In Goldsboro, MD 313 crosses an unused railroad grade owned by the Maryland Department of Transportation and intersects the southern terminus of MD 311 (Main Street), continuing through residential areas before coming to an intersection with the western terminus of MD 287 (Old Line Road). Here, the route makes a left turn to head west on Goldsboro Road. MD 313 leaves Goldsboro and heads into a mix of farmland and woodland. The road curves northwest and intersects unsigned MD 820 (Castle Hall Road), where it heads back to the west. MD 313 turns to the northwest and intersects the northern terminus of MD 312 (Oakland Road) in Baltimore Corner, where it heads north through farm fields past that intersection.