After the fall of the Amezcua brothers – founders of the Colima Cartel – in 1999 on methamphetamine trafficking charges, there was a demand for leadership throughout Mexico to coordinate methamphetamine shipments north. Guzmán saw an opportunity and seized it. Easily arranging precursor shipments, Guzmán and Ismael Zambada García ("El Mayo") made use of their previous contacts on Mexico's Pacific coast. Importantly, for the first time, the Colombians would not have to be paid – they simply joined methamphetamine with cocaine shipments. This fact meant no additional money was needed for airplanes, pilots, boats and bribes; they used the existing infrastructure to pipeline the new product.