Skepticism (American and Canadian English) or scepticism (British, Irish, Australian, and New Zealand English) is generally a questioning attitude or doubt towards one or more putative instances of knowledge which are asserted to be mere belief or dogma. Formally, skepticism is a topic of interest in philosophy, particularly epistemology. More informally, skepticism as an expression of questioning or doubt can be applied to any topic, such as politics, religion, or pseudoscience. It is often applied within restricted domains, such as morality (moral skepticism), theism (skepticism about the existence of God), or the supernatural.