In an extra-inning game against the Pittsburgh Pirates on April 3, 2008, Resop pitched a third of an inning and allowed two walks in the top of the 10th inning. Manager Bobby Cox then brought in left-handed pitcher Royce Ring to face left-handed batter Adam LaRoche and substituted Resop for Matt Diaz in left field. After Ring struck out LaRoche, Gregor Blanco came in to play left and Resop returned to the mound in place of Ring. He subsequently allowed an RBI single to Xavier Nady and earned the loss as the Pirates won 4–3.