Hampton played college football at Arkansas and was drafted in the first round of the 1979 NFL Draft by the Bears. He was part of a Razorback team that thumped the highly favored Oklahoma Sooners in the 1978 Orange Bowl by a score of 31-6. Several key Razorback players had been suspended for the game by Arkansas Head Coach Lou Holtz which left the team short-handed. The fired up Razorbacks charged from the locker room in a fashion that the media noticed. When asked why the team came out of the locker room in such a hurry, Hampton answered, "Coach Holtz said the first eleven out of the locker room will start."