Despite Brady's success, the Patriots were hit by many injuries to key players on offense, including wide receiver Julian Edelman, and the Patriots eventually lost their first game against the Denver Broncos, who were without Peyton Manning, in Denver following a 10–0 start. The Patriots then lost three of their remaining five games to finish 12–4 for a fourth straight season, earning the 2-seed in the AFC. Brady finished the regular season with a league-leading 36 touchdown passes and seven interceptions. He was named to his 11th Pro Bowl (seventh straight), and was ranked as the second best player on the "NFL Top 100 Players of 2016" behind only league MVP Cam Newton.