In the summer before the 2012–13 Premier League, Krul was given the number 1 jersey, with Steve Harper receiving number 37. Krul was started the first three matches of the season before suffering an elbow injury whilst on international duty. After seven weeks off, Krul returned to training. Krul made his return in the Tyne–Wear derby on 21 October 2012, a 1–1 draw. He injured his ankle during a Europa League match in the Round of 32 against Ukrainian side Metalist Kharkiv which ruled him out for five weeks. In the Tyne–Wear derby on 14 April 2013, Krul suffered a dislocated shoulder on 57th minutes after he landed awkwardly after punching away an Adam Johnson free-kick. After surgery on his dislocated shoulder, Krul was ruled out for the rest of the 2012–13 season.