As with yeomen farmers in much of East Tennessee, those in Greene County were generally Unionist and opposed to secession on the eve of the Civil War. In Tennessee's Ordinance of Secession referendum on June 8, 1861, Greene Countians voted against secession by a vote of 2,691 to 744. Following the vote (the call for secession was passed statewide), the second session of the East Tennessee Convention convened in Greeneville. It called for a separate, Union-aligned state to be formed in East Tennessee.