Soon after the meeting at Pallathuruthy, which was the last public function he attended, Guru became ill and underwent treatment at places such as Aluva, Thrissur, Palakkad, and finally to Chennai; the physicians attended to him included Ayurvedic physicians like Cholayil Mami Vaidyar, Panappally Krishnan Vaidyar and Thycauttu Divakaran Moos as well as allopathic physicians viz. . Krishnan Thampi, Panikker, Palpu and a European physician by name, Noble. He returned to Sarada Mutt and it was here, he died on 20 September 1928, at the age of 72.