In 1542 an insurrection of the Indians, called the Mixtón Rebellion threatened to push the Spaniards out of northwestern Mexico, bringing the area under indigenous control. The Viceroy himself had to take the field and bring all disposable manpower. The rebellion was quashed and the surviving Indians were harshly punished. By the viceroy's order men, women and children were seized and executed, some by cannon fire, some torn apart by dogs, and others stabbed. In 1548 he suppressed an uprising of the Zapotecs.