During his career, Harrison was selected to two Pro Bowls and received first-team All-Pro honors three times. He holds the record for sacks by a defensive back at 30.5 and is the first NFL player to obtain 30 sacks and 30 interceptions. Harrison participated in four Super Bowls, winning two with the Patriots in Super Bowl XXXVIII and Super Bowl XXXIX. In recognition of his accomplishments in San Diego and New England, he was named to the 50th Anniversary Teams of both the Chargers and Patriots. He was also inducted to the Patriots Hall of Fame in 2019.