The two have publicly discussed their fertility issues on television talk shows, having tried to conceive since approximately the beginning of 2009. The couple began in vitro fertilization (IVF) in March 2010, and Rancic got pregnant in the spring of 2010, but she miscarried at nine weeks. She had an IVF transfer for a second time in November 2010; however, the procedure did not result in a pregnancy. When the couple decided to try for a third round of IVF, her doctor recommended a mammogram, which is how she found out she had breast cancer. Despite her condition, the couple were still motivated to have a baby, so they continued with the egg retrieval and found a surrogate.