Osanna was a mystic who would fall into ecstasies whenever she spoke of God, and a visionary who saw images of Christ bearing his cross. She bore stigmata along with red marks, but there was no bleeding. She helped the poor and sick and served as spiritual director for many, spending much of her family's considerable fortune to help the unfortunate. She spoke out against decadence, and criticized the aristocracy for a lack of morality. She was a friend of another member of her Order, Columba of Rieti, and is recorded to have sought counsel from another, the Stephana de Quinzanis.