In the series "Wolverine: Origins", following Wolverine's full memories regained, and embarking on a mission to take care of loose ends, the U.S. government dispatches Nuke to hunt Wolverine down. Though Wolverine dispatches Nuke, it is revealed that Nuke's enhanced physiology has further mutated, giving him cybernetic limbs, bones and skull, and the ability to survive the most gruesome injuries, but has left him devoid of any personality or conscience. When Wolverine tries to kill him, Captain America intervenes, believing that Nuke is a failed subject of the Super Soldier Program. Wolverine asks the telepath Emma Frost to restore Nuke's broken mind, saying that he’ll euthanize Nuke if he determines this is not possible.