He was selected to four Pro Bowls and was a key defensive member of the Bears' Super Bowl XX win against the New England Patriots in 1986. Hampton was a versatile defensive lineman, making All-Pro at both defensive end and defensive tackle. In all, Hampton was 1st or 2nd team All-Pro in 1980, 1982, 1984, 1985, 1986, and 1988. His versatility likely cost him several post-season honors, for example, in 1986 he was an alternate for the Pro Bowl at both defensive end and defensive tackle. His playing both positions likely split the votes of his NFC peers. Hampton was also a 1st alternate for the Pro Bowl in 1988 and graded out as the top defender on the Bears that season, even though Mike Singletary was the NFL Defensive Player of the Year.