US 29 enters Virginia in Danville from North Carolina, immediately splitting into business and by-pass routes. US 29 joins the Danville Expressway and US 58 around the east side of Danville, entering Pittsylvania County, and re-merging with the business route north of town in Blairs. The interchange where the split of US 29 into Business and Bypass routes/junction with US 58 occurs has ramps that enter North Carolina and ramps that enter Virginia, complete with welcome signs from each state. There is a cloverleaf ramp that dips into North Carolina from Virginia and then crosses the state lines back into Virginia. Along the southeastern quadrant of the Danville Expressway between the North Carolina US 360, the route is designated as part of unsigned State Route 785 for . Created , SR 785 is numbered in contradiction to the conventional system of numbering in the state, where primary routes are numbered less than 600 and secondary routes at or above this number. It is numbered as such because it is part of the planned Interstate 785, which will run south along US 29 to Interstate 85 in Greensboro, North Carolina, and is only one of two routes of this type. The other is Route 895 in Richmond for similar reasons.