The story is similar to an earlier Bela Lugosi movie, "The Corpse Vanishes" (1942). In both movies, each bride at her wedding was given an orchid, which she sniffed before passing out. In "The Corpse Vanishes", Lugosi played a doctor who captured the brides and took some kind of liquid from each bride's body and injected it into his wife to make her temporarily young again. Characters included his wife, an old woman, the old woman's grown son, and a dwarf. In "Bride of the Monster", Lugosi again plays a doctor doing experiments, but his only housemate/assistant is Lobo, and when his experiment fails to turn someone into an "atomic-powered superman", he throws the dead subject to an octopus or an alligator, similar to Lugosi throwing a body into a river in "Murders in the Rue Morgue" (1932).