The character's name is a portmanteau of the words "brain" and "maniac". In 2009, Brainiac was ranked by IGN as 17th Greatest Comic Book Villain of All Time. He has been substantially adapted into various forms of media, having been voiced by Corey Burton in various television shows set within the DC animated universe, by John Noble in animated film "", and by Jeffrey Combs in the video game "Injustice 2". In live-action television, Brainiac has been portrayed by James Marsters on "Smallville" and by Blake Ritson on "Krypton".