Amerson's role as a rusher was greatly reduced in 1999, both due to his early knee injury and the returning Williams, who developed into the team's featured power back. Amerson's only significant rushing play was a career-high 70-yard touchdown run in late September. After Amerson re-injured his knee in October, Tony Akins received his first start in which he recorded 257 receiving yards. After Akins' first game, head coach Ron Lancaster told the media that Amerson would primarily be used as a kick returner going forward, with Akins remaining in the lineup even after Amerson returned. Despite this, Amerson continued to see time as both a receiver and punt returner upon his return later that month. He finished the season with 47 receptions for 700 yards and five touchdowns through 13 games played. The Hamilton Tiger-Cats defeated the Calgary Stampeders 32–21 in the 87th Grey Cup, making Amerson a Grey Cup champion.