Heather Webber married Edward to get her hands on Lila's fortune. The plan failed when Justus was named Lila's heir, and Heather tried to kill Edward. Luke and Skye caught on to her plan, and set Heather up. She went crazy, and Edward had the marriage annulled, then shipped her off to Shadybrook. Edward lived through losing many family members – A.J., Justus, and Alan. Luke was the one who helped him move past losing his family. Edward was eager to provide for Elizabeth Spencer's son, Jake, when he suspected Jason was Jake's father. Edward, Monica, and Alice cornered Lulu, but Lulu told them that Jason was not Jake's father, and Edward was crushed. The Quartermaines suffered another devastating loss when Emily was killed by Diego Alcazar. Skye was the one to tell Edward about Emily, and before breaking down in her arms, he told her the story of how he had always wanted to be like Joseph F. Kennedy Sr., but as Kennedy's life progressed, his life fell apart. Edward feels his life has become like this and he has turned into a kind of poison. He even goes as far as telling Skye to leave town before she dies too.