Homochiral MOFs have been made by Lin and coworkers using 2,2′-bis(diphenylphosphino)-1,1′-binaphthyl (BINAP), 1,1′-bi-2,2′-naphthol (BINOL) as a chiral ligands. These ligands can coordinate with catalytically active metal sites to enhance the enantioselectivity. A variety of linking groups such as pyridine, phosphonic acid, and carboxylic acid can be selectively introduced to the 3,3′, 4,4′, and the 6,6′ positions of the 1,1'-binaphthyl moiety. Moreover, by changing the length of the linker ligands the porosity and framework structure of the MOF can be selectivily tuned.