On November 30, Conley put up a season-high 28 points in a 98–96 victory over the Los Angeles Lakers. Conley averaged 13.7 and 6.5 assists on the year to help the Grizzlies make the playoffs for the first time in five years. Entering with the eighth seed in the Western Conference, they were matched up in the first round with the top-seeded San Antonio Spurs. Conley and the Grizzlies went on to defeat the Spurs in six games and make NBA history as only the second eighth-seeded team to defeat a first seed in a seven-game series. They then lost to the Oklahoma City Thunder in the Semifinals after seven games.