He organized and directed the Institute of Prices and Business Cycles in 1928. From 1929, he was professor in the Warsaw School of Economics. He founded the Central Statistical Office and the Polish Economic Association. He also served as president of the Economic Association (1945–65), was editor of the periodical "Ekonomista" ('The Economist'), and a member of the Polish Academy of Sciences. Being Poland's foremost economist, Lipiński was also a notable author whose works are widely read in his native Poland, though many have not yet been translated into English. In 1938, he actively opposed the antisemitic campaign carried out at institutions of higher learning by Polish nationalistic factions and supported by the Camp of National Unity party, which forced him to resign from his position at the School of Economics. During the occupation of Poland in World War II, Professor Lipiński held underground classes.