The manga was adapted into a 26-episode anime series produced by Bones titled which aired on TV Tokyo from April 1, 2001 – September 23, 2001. Seven volumes of videos were released by ADV Films on VHS and DVD in 2003. It was re-released in 2005 as a five volume box set. North American publisher Dark Horse Comics re-releases "Angelic Layer" in omnibus format in 2011. Sentai Filmworks will re-release the series under their Sentai Selects label on November 24, 2015. Anime Limited announced they would release the series in the UK in 2018.