The song was nominated for Best Rap Performance by a Duo or Group at the Grammy Awards of 2006, but lost to The Black Eyed Peas song "Don't Phunk with My Heart". No music video was filmed for this song. Eminem, Dre and 50 Cent would later return to work together on the song "Crack a Bottle" from "Relapse". On "Encore", "One Shot 2 Shot" segues into the skit "Final Thought", which then segues into Encore, which also segues into the "Curtains Down" skit.