In the Patriots' divisional playoff game against the Colts, Harrison intercepted Peyton Manning late in the game to end the Colts' last chance. The next week in the AFC Championship, Harrison jumped a Ben Roethlisberger pass and took it 87 yards for a touchdown, helping the Patriots defeat the Pittsburgh Steelers, 41–27. During the week leading up to the Super Bowl, Harrison got into a verbal feud with Philadelphia Eagles receiver Freddie Mitchell after Mitchell claimed he "had something for Harrison" and did not know the names of the New England secondary. Harrison, in Super Bowl XXXIX, would record seven tackles, a sack, and two interceptions of quarterback Donovan McNabb, despite missing almost an entire quarter due to an injury sustained during the game. The second interception, with ten seconds remaining in the game, preserved a 24–21 Patriot win, ensuring a third championship in four years.