USS "Wainwright" was commissioned into the United States Navy on 12 May 1916 under the command of Lieutenant Fred H. Poteet. After fitting out at Philadelphia, the destroyer rounded Cape May on 20 June and headed for Newport, Rhode Island, to load torpedoes before joining Division 8 of the Atlantic Fleet Destroyer Flotilla. Following exercises near Eastport, Maine, she remained on the New England coast until mid-September when she headed south for gunnery tests and training off the Virginia capes. Upon the completion of a fortnight's gun drills, the ship then returned to Buzzard's Bay, Massachusetts, on 2 October. Later that month, "Wainwright" operated out of Newport, practiced torpedo tactics near Vineyard Sound, and visited New York to pick up cargo for the flotilla's tender, . She returned to Newport on the 18th and, eight days later, resumed torpedo practice near Vineyard Sound for the remainder of the month. She put into Boston, Massachusetts on 1 November for extensive repairs in the navy yard.