"P. gingivalis" virulence is heavily associated with fimbriae as they have been characterized to be key factors in adhesion, invasion, and colonization. Fimbriae are also responsible for invasion of membrane vesicles into host cells. They were found to bind to cellular α5β1 integrins, which mediated adherence and impaired the homeostatic controls of host cells. Fimbriae were also found to be associated with modulating β2 integrin adhesive activity for uptake by monocytes using the CD14/TLR2/PI3K signaling complex, which may contribute to intracellular evasion tactics by "P. gingivalis". "P. gingivalis" has long fimbriae, short fimbriae, and accessory components, each of which have distinct functions.