As of April 2020, the nonprofit had distributed more than 145,000 pounds of medical aid in response to COVID-19. Direct Relief had shipped to hospitals and clinics in all 50 U.S. states, as well as institutions in 32 countries. The organization also started its new COVID-19 Fund for Community Health to provide community health centers with financial support for healthcare workers. 3M donated $10 million to the Fund. By June 2020, over 518 health centers had received funding through the COVID-19 Fund.