council decis march supplement direct eec criteria establish safeti human health environ type genet modifi micro organ text eea relev ec council european union regard treati establish european commun regard council direct eec april contain genet modifi micro organ articl thereof regard propos commiss articl direct eec direct appli contain involv type genet modifi micro organ gmm meet criteria list part annex ii thereto establish safeti human health environ virtu articl direct eec criteria establish safeti human health environ type genet modifi micro organ includ part annex ii direct adopt order facilit applic criteria made commiss adopt detail guidanc note accord procedur refer articl direct direct eec supplement adopt decis articl part annex ii direct eec replac text annex decis articl decis publish offici journal european commun articl decis appli dai public offici journal european commun articl decis address member state brussel march council presid larsson oj direct amend direct ec oj annex quot part criteria establish safeti gmm human health environ annex describ gener term criteria met establish safeti type gmm human health environ suitabl inclus part supplement guidanc note easi applic criteria note develop amend commiss accord procedur refer articl introduct type genet modifi micro organ gmm list part accord procedur refer articl exclud scope direct gmm ad list case case basi exclus relat identifi gmm exclus appli gmm condit contain defin articl appli deliber releas gmm gmm list part prove meet criteria gener criteria strain verif authent ident strain precis establish modif verifi document establish evid safeti document evid safeti organ provid genet stabil instabl advers affect safeti evid stabil requir specif criteria pathogen gmm capabl caus diseas harm healthi human plant anim pathogen includ toxigen allergen gmm toxigen gmm produc increas toxigen result genet modif note toxigen properti allergen gmm produc increas allergen result genet modif note allergen allergen compar micro organ identifi council direct eec octob amend direct eec protect worker risk relat exposur biolog agent work harm adventiti agent gmm harbour harm adventiti agent micro organ activ latent exist alongsid insid gmm harm human health environ transfer genet materi modifi genet materi give rise harm transfer transmiss transfer frequenc greater gene recipi parent micro organ safeti environ event signific unintend releas gmm produc advers effect environ delai incid involv signific unintend releas occur gmm meet criteria includ part quot oj