commiss regul ec juli lai measur adopt evalu programm applic regul ec european parliament council text eea relev commiss european commun regard treati establish european commun regard regul ec european parliament council octob lai commun procedur flavour substanc intend foodstuff articl thereof commiss decis ec adopt regist flavour substanc foodstuff drawn applic regul ec regul ec lai annex gener criteria flavour substanc cover present risk health consum mislead consum order check flavour substanc contain regist compli gener criteria articl regul ec programm evalu flavour substanc carri articl substanc delet regist evalu clear compli gener criteria step evalu programm substanc regist receiv fl number chemic characterist distribut group structur relat compound expect show metabol biolog behaviour common light larg number flavour substanc regist deadlin set regul list authoris flavour substanc adopt evalu programm wast scientif resourc make safeti assess perform committe expert flavour substanc council europ cef scientif committe food european commiss scf joint fao expert committe food addit jecfa scientif committe food consult address question result evalu scientif committe accept conclus express decemb scf opinion subject except flavour consid accept current estim intak jecfa compli gener criteria includ list authoris substanc undergo separ scf evalu time likewis scf conclud flavour previous evalu scf cef safe evalu criteria previous stringent substanc safe current scientif committe food consid remain flavour substanc unnecessari duplic work avoid divid group substanc jecfa scf evalu articl regul ec person respons place substanc market forward data evalu commiss inform substanc puriti chemic specif natur occurr food total amount ad food result toxicolog metabol studi consid essenti evalu order enabl constant evalu period inform present advanc evalu substanc inform updat data data provid chemic ident substanc amount ad food toxicolog metabol studi substanc close relat substanc insuffici data request initi exposur assess base total amount ad food refin usag data evalu substanc order enabl complet evalu programm year deadlin submiss inform set minim number substanc evalu time period inform provid evalu flavour substanc undertaken substanc includ definit list flavour substanc refer articl regul ec regist substanc opinion scf conclud substanc evalu time base assumpt jecfa evalu consider number substanc year remain evalu scf order make evalu process effici group base approach substanc expect show metabol biolog behaviour common evalu commiss decis ec amend decis ec task quot chemic defin flavour substanc quot defin undertaken framework scientif cooper member state examin question relat food scoop task built flavi databas compil inform scientif evalu flavour substanc inform provid person respons place substanc market ad databas critic review order establish suffici complet evalu accord opinion scf evalu substanc scf follow procedur appli jecfa updat systemat procedur present appli approv scf result futur evalu flavour substanc regist perform jecfa accept jecfa procedur stepwis approach integr inform intak current structur activ relationship metabol toxic addit inform puriti chemic specif assess kei element procedur subdivis flavour structur class human exposur threshold consid present safeti concern toxicolog metabol studi perform group chemic relat substanc draw conclus toxicolog effect substanc studi studi intens substanc evalu light data toxicolog effect human intak doubt aris valid perform accept evalu commiss decis ec flavour substanc receiv prioriti evalu programm concern safeti health consum express member state programm proce group wise give prioriti group substanc inform higher prioriti substanc request futur measur provid regul accord opinion stand committe foodstuff adopt regul articl step establish evalu programm attribut fl number defin flavi databas system flavour substanc regist subdivis substanc group relat substanc list group laid annex regul stage complet month adopt regul member state particip scoop task establish decis ec articl substanc contain regist classifi scf categori substanc consid safe cef categori substanc foodstuff jecfa present safeti concern current level intak except substanc accept sole basi estim intak lower threshold concern μg person dai laid report st jecfa meet evalu present evalu programm inform puriti chemic specif substanc outlin annex ii provid scf receiv inform chang result evalu substanc contain regist classifi futur jecfa present safeti concern current level intak consid scf decid evalu event scf decid evalu substanc refer paragraph person respons place substanc regist market provid inform laid articl articl person respons place market substanc contain regist cover articl provid inform month adopt regul order enabl evalu substanc puriti chemic specif substanc outlin annex ii natur occurr foodstuff total amount substanc ad food commun normal maximum level substanc food categori outlin annex iii relev toxicolog metabol studi substanc close relat substanc inform transmit standardis format outlin annex iv inform refer paragraph substanc month adopt regul person respons place market inform commiss period date fulfil oblig paragraph individu substanc group substanc laid annex light inform receiv paragraph commiss establish deadlin propos paragraph individu substanc group substanc laid annex order smooth run evalu process commiss request addit inform consid relev evalu substanc person respons place market deadlin consist deadlin programm substanc submit inform normal maximum level food categori outlin annex iii inform paragraph addit inform paragraph provid substanc evalu inform paragraph updat includ substanc evalu person respons place respect substanc market data inform provid made member state articl substanc year evalu provid inform articl addit inform articl suppli deadlin scoop task establish decis ec particip member state incorpor inform substanc articl flavi databas check inform suffici complet evalu inform commiss case prepar data sheet collat summaris inform pre evalu present data sheet scf scoop task organis meet requir paragraph basi data sheet refer paragraph scf evalu substanc complianc gener criteria scf check inform complet inform commiss case measur restrict level propos evalu procedur appli follow procedur appli jecfa consid scf commiss member state request evalu substanc accept compli gener criteria data lead result articl substanc regist bear remark quot quot quot quot quot comment quot column decis ec evalu prejudic paragraph group substanc laid annex inform refer articl complet receiv prioriti evalu derog paragraph commiss member state request prioriti evalu substanc group substanc articl regul enter forc seventh dai public offici journal european commun regul bind entireti directli applic member state brussel juli commiss david byrn member commiss oj oj oj oj annex minut meet scientif committe food septemb flavour substanc natur sourc flavour volum chemic defin flavour substanc fourth edit council europ partial agreement social public health field strasbourg includ subsequ loos leaf modif year evalu food addit contamin report joint fao expert committe food addit technic report seri geneva evalu food addit contamin report joint fao expert committe food addit technic report seri geneva st report joint fao expert committe food addit technic report seri publish report joint fao expert committe food addit technic report seri publish annex chemic group flavour substanc straight chain primari aliphat alcohol aldehyd acid acet ester ester satur alcohol acet satur aldehyd aromat heteroaromat moieti compon ester acet branch chain primari aliphat alcohol aldehyd acid acet ester ester branch chain alcohol acet branch chain aldehyd aromat heteroaromat moieti compon ester acet unsatur alken alkyn straight chain branch chain aliphat primari alcohol aldehyd acid acet ester ester unsatur alcohol acet unsatur alcohol aldehyd aromat heteroaromat moieti compon ester acet conjug accumul unsatur straight chain branch chain aliphat primari alcohol aldehyd acid acet ester ester unsatur alcohol acet unsatur alcohol aldehyd aromat heteroaromat moieti compon ester acet satur unsatur aliphat secondari alcohol keton ketal ester ester secondari alcohol aromat heteroaromat moieti compon ester ketal aliphat alicycl aromat satur unsatur tertiari alcohol ester ester tertiari alcohol ester acid compon primari alicycl satur unsatur alcohol aldehyd acid acet ester ester alicycl alcohol ester acet aliphat acycl alicyl acid alcohol compon secondari alicycl satur unsatur alcohol keton ketal ester ketal alicycl alcohol keton ester secondari alicycl alcohol ester aliphat acycl alicycl acid compon primari aliphat satur unsatur alcohol aldehyd acid acet ester primari secondari tertiari oxygen function group includ aliphat lacton secondari aliphat satur unsatur alcohol keton ketal ester secondari tertiari oxygen function group alicycl aromat lacton maltol deriv ketodioxan deriv furanon tetrahydrofurfuryl deriv furfuryl furan deriv addit side chain substitu heteroatom phenyl ethyl alcohol phenylacet acid relat ester phenoxyacet acid relat ester aliphat alicycl ether propenylhydroxybenzen allylhydroxybenzen capsaicin relat substanc relat amid aliphat aromat mono di thiol mono di tri polysulfid addit oxygen function group aromat keton secondari alcohol relat ester aryl substitut primari alcohol aldehyd acid ester acet deriv includ unsatur benzyl alcohol aldehyd acid ester acet benzyl benzoat ester includ aliphat acycl alicycl ester acet compon pyrazin deriv phenol deriv ring alkyl ring alkoxi side chain oxygen function group aromat ether includ anisol deriv anthranil deriv pyridin pyrrol quinolin deriv thiazol thiophen thiazolin thienyl deriv miscellan substanc aliphat aromat hydrocarbon epoxid aliphat aromat amin amino acid chemic base group expect show metabol biolog behaviour common annex ii chemic specif provid flavour substanc chemic regist decis ec iupac chemic regist synonym ca einec fl coe fema number chemic structur formula molecular weight physic form odour solubl solubl ethanol ident test infra red nuclear magnet reson mass spectrum minimum assai impur physic paramet relat puriti justif requir inform provid boil point liquid melt point solid refract index liquid specif graviti liquid stabil decomposit product relev interact food compon relev relev inform annex iii food categori dairi product exclud product categori fat oil fat emuls type water oil edibl ic includ sherbet sorbet process fruit veget includ mushroom fungi root tuber puls legum nut seed fruit veget includ mushroom fungi root tuber puls legum nut seed confectioneri cereal cereal product includ flour starch root tuber puls legum exclud bakeri bakeri ware meat meat product includ poultri game fish fish product includ mollusc crustacean echinoderm mce egg egg product sweeten includ honei salt spice soup sauc salad protein product foodstuff intend nutrit beverag exclud dairi product alcohol quot soft quot beverag alcohol beverag includ alcohol free low alcohol counterpart readi eat savouri composit food casserol meat pi mincemeat food categori annex iv format transmiss inform flavour substanc inform articl fourth indent summari inform request indent provid standard electron format quot input form flavi databas quot fl summari inform request indent main find refer studi conclus metabol toxicolog effect substanc fl download internet site order coordin institut scoop task address http www flavi net inform provid english identifi substanc column head quot quot english version regist decis ec fl number addit complet fl coordin institut scoop task mail address input flavi net abovement internet site post address recommend substanc part regist separ bound copi inform articl indent provid paper format copi identifi english quot quot substanc chemic group list annex relat fl number addit copi coordin institut scoop task danish veterinari food administr institut food safeti toxicolog flavi mørkhøi bygad dk søborg