council direct juli place plant protect product market eec council european commun regard treati establish european econom commun articl thereof regard propos commiss regard opinion european parliament regard opinion econom social committe plant product import place commun plant product yield continu affect harm organ includ weed absolut essenti protect plant risk prevent declin yield ensur secur suppli import wai protect plant plant product improv agricultur product plant protect product plant protect product benefici effect plant product involv risk hazard human anim environ market offici test author incorrectli view hazard rule member state govern author plant health product rule present differ constitut barrier trade plant protect product trade plant product directli affect establish oper intern market desir elimin barrier harmon provis laid member state uniform rule condit procedur author plant protect product appli member state rule provid plant protect product put market habe offici author properli regard principl good plant protect practic integr pest control provis govern author ensur high standard protect prevent author plant protect product risk health groundwat environ human anim health prioriti object improv plant product time plant protect product author make properli appli purpos intend suffici effect unaccept effect plant plant product unaccept influenc environ gener harm effect human anim health groundwat author limit plant protect product activ substanc commun level basi toxicolog ecotoxicolog properti establish commun list author activ substanc commun procedur laid assess activ substanc enter commun list inform interest parti submit view admiss substanc list commun procedur prevent member state author territori limit period plant protect product activ substanc enter commun list provid interest parti submit dossier meet commun requir member state conclud activ substanc plant protect product expect satisfi commun condit set regard interest safeti substanc commun list review period account develop scienc technolog impact studi base actual plant protect product substanc interest free movement plant product plant protect product author grant member state test carri view author recogn member state agricultur plant health environment includ climat condit relev product concern compar region concern end harmon method experiment control appli member state purpos grant author desir system mutual suppli inform establish member state make request particular scientif document submit connect applic author plant protect product member state enabl author plant protect product compli abovement condit unforese danger threaten plant product counter mean author review commun close cooper member state framework stand committe plant health direct complement commun provis classif packag label pesticid provis consider improv protect user plant protect product consum plant plant product contribut protect environ maintain consist direct commun rule residu plant protect product agricultur product free movement commun direct complement commun provis relat maximum permiss level pesticid residu facilit adopt level commiss provis consider improv protect consum plant plant product resourc devot conduct test vertebr anim dissip result differ law member state consider public interest council direct eec novemb approxim law regul administr provis member state protect anim experiment scientif purpos milit needless repetit test anim order ensur requir laid satisfi member state make provis control inspect arrang regard market plant protect product procedur provid direct evalu risk environ present plant protect product compos genet modifi organ correspond principl laid direct eec april deliber releas environ genet modifi organ futur suppli data accord part annex ii iii subject specif requir provis made amend direct implement direct adapt annex advanc technic scientif knowledg necessit close cooper commiss member state procedur stand committe plant health offer suitabl basi cooper adopt direct scope articl direct concern author place market control commun plant protect product commerci form place oj oj market control commun activ substanc intend articl direct appli prejudic council direct eec june approxim law member state relat classif packag label danger prepar pesticid amend direct eec activ substanc concern prejudic provis classif packag label council direct eec june approxim law regul administr provis relat classif packag label danger substanc amend direct eec direct appli author place market plant protect product compos genet modifi organ provid author releas environ grant risk environ assess accord provis part relev provis part direct eec commiss submit council suffici time act year date notif direct propos amend view includ direct amp specif procedur evalu risk environ analog provid direct eec enabl direct list provid articl direct eec accord procedur laid articl year date notif direct commiss basi experi gain provid european parliament council report oper arrang subparagraph direct appli prejudic council regul eec june export import commun danger chemic definit articl purpos direct definit appli plant protect product activ substanc prepar activ substanc put form suppli user intend oj oj oj oj amp direct notifi member state juli oj protect plant plant product harm organ prevent action organ substanc prepar defin influenc life process plant nutrient growth regul preserv plant product substanc product subject special council commiss provis preserv destroi undesir plant destroi part plant check prevent undesir growth plant residu plant protect product substanc present plant product plant origin edibl anim product environ result plant protect product includ metabolit product result degrad reaction substanc chemic element compound occur natur manufactur includ impur inevit result manufactur process activ substanc substanc micro organ includ virus gener specif action harm organ plant part plant plant product prepar mixtur solut compos substanc activ substanc intend plant protect product plant live plant live part plant includ fresh fruit seed plant product product unprocess state undergon simpl prepar mill dry press deriv plant exclud plant defin point harm organ pest plant plant product belong anim plant kingdom virus bacteria mycoplasma pathogen anim anim belong speci fed consum man place market suppli return payment free charg storag consign territori commun dispos import plant protect product territori commun deem constitut place market purpos direct author plant protect product administr act compet author member state author applic submit applic place market plant protect product territori part thereof environ water air land wild speci fauna flora interrelationship relationship live organ integr control ration applic combin biolog biotechnolog chemic cultur plant breed measur chemic plant protect product limit strict minimum maintain pest popul level caus econom unaccept damag loss gener provis articl member state prescrib plant protect product market territori author product accord direct intend cover articl member state ground plant protect product author territori imped product storag movement product intend member state provid product author member state inspect requir laid member state order ensur complianc paragraph satisfi member state prescrib plant protect product properli proper includ complianc condit establish accord articl label applic principl good plant protect practic principl integr control member state prescrib activ substanc market classifi packag label accord direct eec activ substanc market year notif direct dossier forward member state commiss accord articl declar activ substanc intend articl condit appli activ substanc intend articl grant review withdraw author plant protect product articl member state ensur plant protect product author activ substanc list annex condit laid fulfil regard point pursuant uniform principl provid annex vi establish light current scientif technic kowledg shown apprais dossier provid annex iii accord articl regard normal condit consequ ii suffici effect ii unaccept effect plant plant product iii unnecessari suffer pain vertebr control iv harm effect human anim health directli indirectli drink water food feed groundwat unaccept influenc environ regard consider fate distribut environ contamin water includ drink water groundwat impact target speci natur quantiti activ substanc toxicolog ecotoxicolog signific impur formul determin method harmon procedur provid articl agre author respons author residu result author toxicolog environment signific determin method gener physic chemic properti determin deem accept purpos storag product maximum residu level agricultur product refer author provision establish member state notifi commiss accord articl month notif commiss provision maximum level establish member state accept accord procedur laid articl establish provision maximum level commun remain forc maximum level adopt pursuant procedur provid subparagraph articl direct eec articl direct eec amend direct eec member state prohibit imped introduct territori product pesticid residu provid residu level exce provision maximum level set accord subparagraph ii member state ensur condit approv appli provision maximum level exceed author stipul requir relat place market product aim ensur complianc provis paragraph member state ensur complianc requir set paragraph establish oj oj oj offici offici recogn test analys carri agricultur plant health environment condit relev plant protect product question repres prevail product intend territori member state concern prejudic paragraph author grant fix period year determin member state renew verif condit impos paragraph satisfi renew grant period compet author member state verif applic renew made author review time indic requir refer paragraph longer satisfi instanc member state requir applic author parti extens field applic grant accord articl submit inform review author extend period complet review provid inform prejudic decis pursuant articl author cancel establish requir obtain author longer satisfi fals mislead particular suppli fact basi author grant modifi establish basi develop scientif technic knowledg manner amount modifi cancel modifi request holder author state reason therefor amend grant establish requir articl continu satisfi member state withdraw author immedi inform holder author grant period grace dispos storag place market exist stock length accord reason withdraw prejudic period provid decis council direct eec decemb prohibit place market plant protect product activ substanc amend direct eec amp articl articl direct oj amp oj inclus activ substanc annex articl light current scientif technic knowledg activ substanc includ annex initi period exceed year expect plant protect product activ substanc fulfil condit residu consequ applic consist good plant protect practic harm effect human anim health groundwat unaccept influenc environ residu toxicolog environment signific measur method gener consequ applic consist good plant protect practic harm effect human anim health anaccept influenc environ provid articl iv inclus activ substanc annex account relev accept daili intak adi man accept oper exposur level relev estim fate distribut environ impact target speci inclus activ substanc market year notif direct requir deem satisfi establish prepar containg activ substanc inclus activ substanc annex subject requir minimum degre puriti activ substanc natur maximum content impur restrict aris evalu inform refer articl take account agricultur plant health environment includ climat condit question type prepar manner request inclus substanc annex renew period exceed year inclus review time indic criteria refer paragraph longer satisfi renew grant period complet review applic made renew suffici time case year entri due laps grant period provid inform request accord articl articl inclus activ substanc annex decid accord procedur laid articl decid accord procedur condit inclus amend annex remov activ substanc form annex longer satisfi requir articl member state receiv applic inclus activ substanc annex undu delai ensur dossier believ satisfi requir annex ii forward applic member state commiss dossier compli annex iii prepar activ substanc commiss refer dossier stand committe plant health refer articl examin prejudic provis paragraph request member state month date referr committe mention articl establish procedur laid articl dossier submit accord requir annex ii iii assess dossier refer paragraph show inform commiss applic submit inform applic author repres ask commiss submit remark unfavour decis envisag provis appli inclus activ substanc annex fact emerg cast doubt conform requir articl renew accord articl consid procedur submiss apprais applic inclus annex set vari condit inclus adopt accord procedur laid articl inform potenti harm effect articl member state prescrib holder author extens field applic grant accord articl immedi notifi compet author inform potenti danger effect plant protect product residu activ substanc human anim health groundwat potenti danger effect environ member state ensur parti concern immedi notifi inform member state commiss refer inform committe refer articl transit measur derog articl derog articl member state enabl gradual assess made properti activ substanc make easier prepar made agricultur author provision period exceed year place market plant protect product activ substanc list annex market year notif direct provid applic articl found dossier activ substanc satisfi requir annex ii iii relat project member state establish activ substanc satisfi requir articl plant protect product expect satisfi requir articl case member state immedi inform member state commiss assess dossier term author give inform provid articl evalu dossier provid articl decid accord procedur laid articl activ substanc satisfi requir articl case member state ensur author withdrawn derog articl expiri year period decis inclus activ substanc annex period order procedur refer articl enabl full examin made dossier addit inform request accord articl provis articl appli author grant term paragraph prejudic forego subparagraph derog articl prejudic paragraph direct eec member state period year notif direct author place market territori plant protect product activ substanc list annex market year date notif direct adopt direct commiss commenc programm work gradual examin activ substanc year period refer forego subparagraph programm requir interest parti submit requisit data commiss member state period provid programm regul adopt procedur laid articl set provis implement programm ten year notif direct commiss present european parliament council progress report programm depend conclus report decid procedur laid articl substanc year period refer subparagraph extend period determin year period refer subparagraph examin committe refer articl activ substanc decid procedur laid articl substanc includ annex condit case requir articl satisfi requisit inform data submit prescrib period activ substanc includ annex member state ensur relev author grant withdrawn vari prescrib period review plant protect product activ substanc accord paragraph review place member state appli requir laid articl accord nation provis data provid derog articl special circumst member state author period exceed dai place market plant protect product compli articl limit control measur appear unforese danger contain mean case member state concern immedi inform member state commiss action decid delai accord procedur laid articl condit action member state extend period repeat revok applic author articl applic author plant protect product made behalf person respons place market member state compet author member state plant protect product intend market offici scientif bodi involv agricultur activ profession agricultur organ profession user request field applic plant protect product author member state question extend purpos cover author member state grant extens field applic author plant protect product oblig grant extens public interest extent document inform support extens field applic submit applic establish condit refer articl iii iv satisfi intend minor natur user fulli specif inform instruct mean addit label fail mean offici public applic requir perman offic commun member state requir applic author submit nation offici languag languag requir sampl prepar ingredi provid member state agre applic author made decid thereon reason period provid scientif technic structur dispos member state ensur file compil applic file copi applic record administr decis member state applic particular document laid articl summari member state request make member state commiss file provid paragraph suppli request inform full comprehens applic request ensur applic provid copi technic document laid articl mutual recognit author articl request applic substanti claim compar documentari evid member state applic made author plant protect product author member state refrain requir repetit test analys carri connect author product member state extent agricultur plant health environment includ climat condit relev product compar region concern extent uniform principl adopt accord articl product activ substanc list annex author place product market territori extent agricultur plant health environment includ climat condit relev product compar region concern author subject condit result implement measur accord commun law relat condit distribut plant protect product intend protect health distributor user worker concern subject complianc treati author accompani restrict aris differ dietari pattern order avoid exposur consum treat product risk dietari contamin excess accept daili intak residu concern author subject agreement applic condit order render region concern compar agricultur plant health environment includ climat condit irrelev purpos compar member state inform commiss case requir repetit test case refus author plant protect product author member state respect applic claim agricultur plant health environment includ climat condit relev product region concern member state test carri author grant compar territori notifi commiss ground repetit test requir author refus prejudic articl case member state refus recogn compar accept test analys author place market plant protect product relev region territori decis compar exist accord procedur laid articl decis neg condit compar deem irrelev procedur account inter alia ecolog vulner problem aris commun region zone requir aris specif protect measur member state delai accept test analys author place plant protect product market subject case term decis set articl member state valid reason product author bound author articl constitut risk human anim health environ provision restrict prohibit sale product territori immedi inform commiss member state action give reason decis decis matter month accord theprocedur laid articl exchang inform articl period month end quarter member state inform commiss write plant protect product author withdrawn accord provis direct indic busi holder author trade plant protect product type prepar amount activ substanc intend maximum residu level provision establish set commun rule relev reason withdraw author dossier need evalu maximum residu level provision establish member state draw annual list plant protect product author territori commun list member state commiss accord procedur laid articl standard inform system set facilit applic paragraph data requir data protect confidenti articl prejudic articl member state requir applic author plant protect product submit applic dossier satisfi light current scientif technic knowledg requir set annex iii activ substanc plant protect product dossier satisfi light current scientif technic knowledg requir set annex ii derog paragraph prejudic provis paragraph applic exempt suppli inform requir paragraph identifi activ substanc activ substanc list annex take account condit inclus annex differ significantli degre puriti natur impur composit regist dossier accompani origin applic grant author member state make inform refer annex ii benefit applic applic agre applic made inform period year inclus annex activ substanc market year date notif direct period exceed year date decis member state provid exist nation rule activ substanc market year date notif direct period year date decis receipt inform inclus annex vari condit maintain inclus activ substanc annex year period expir period provid paragraph case period year extend expir date period grant author member state make inform refer annex iii benefit applic applic agre applic made inform period year author plant protect product member state author inclus annex activ substanc contain product period exceed year provid exist nation rule author plant protect product member state author preced inclus annex activ substanc contain product member state examin applic author inform commiss instanc activ substanc list annex produc person manufactur process dossier basi activ substanc includ annex transmit data identifi impur activ substanc derog paragraph activ substanc market year notif direct member state due regard provis treati continu appli previou nation rule data requir long substanc includ annex notwithstand paragraph prejudic articl activ substanc list annex applic author plant protect product carri experi involv vertebr anim enquir compet author member state intend make applic plant protect product applic made plant protect product author grant address holder holder author author enquiri support evid prospect applic intend appli author behalf inform paragraph compet author member state satisfi applic intend appli provid address holder holder previou relev author time inform holder author address applic holder holder previou author applic reason step reach agreement share inform avoid duplic test vertebr anim data request view inclus annex activ substanc market year notif direct compet author member state encourag data holder cooper provis request data view limit duplic test vertebr anim applic holder previou author product reach agreement share data member state introduc nation measur oblig applic holder previou author locat territori share data view avoid duplic test vertebr anim determin procedur util inform reason balanc interest parti concern articl member state commiss prejudic council direct eec june freedom access inform environ ensur inform submit applic involv industri commerci secret treat confidenti applic wish activ substanc includ annex applic author plant protect product request member state commiss accept applic request warrant confidenti appli name content activ substanc substanc plant protect product substanc regard danger direct eec eec physico chemic data activ substanc plant protect product wai render activ substanc plant protect product harmless summari result test establish substanc product efficaci harmless human anim plant environ recommend method precaut reduc handl storag transport fire hazard method analysi refer articl method dispos product packag decontamin procedur case accidenti spillag leakag aid medic treatment case injuri person applic subsequ disclos previous confidenti inform requir inform compet author packag label plant protect product articl articl direct eec appli plant protect product cover direct eec articl member state measur ensur packag plant protect product satisfi requir label packag show indel trade design plant protect product address holder author author number plant protect product address person respons final packag label final label plant protect product market amount activ substanc express provid articl direct eec paragraph articl list contain annex direct eec includ iso common activ substanc design chemic design iupac rule net quantiti plant protect product legal unit measur formul batch number mean identifi particular requir articl direct eec mention paragraph paragraph articl inform aid natur special risk human anim environ mean standard phrase select annex iv safeti precaut protect human anim environ form standard phrase select annex type action plant protect product insecticid growth regul weedkil type prepar wettabl powder emulsifi concentr plant protect product author specif agricultur plant health environment condit product direct dose rate express metric unit provid term author safeti interv applic sow plant crop protect sow plant succeed crop access human anim harvest consumpt particular phytotox variet suscept direct indirect advers side effect plant product plant origin interv observ applic sow plant crop question subsequ crop accompani leaflet provid paragraph sentenc read accompani instruct direct safe dispos plant protect product packag expiri date relev normal condit storag shelf life product limit year member state permit requir paragraph separ leaflet accompani packag space packag small leaflet regard part label purpos direct take account rule forc territori suppli plant protect product categori user pend commun harmon member state requir label product restrict categori user circumst label packag plant protect product bear indic toxic harmless similar indic inform effect plant protect product bee target speci activ crop weed flower phrase protect bee target speci label author relat explicitli season bee organ present minim hazard member state make place plant protect product market territori subject label nation languag languag requir sampl model draft packag label leaflet refer articl submit derog paragraph member state requir addit phrase indel mark packag deem protect human be anim environ event notifi member state commiss forthwith derog grant forward addit phrase phrase reason requir accord procedur laid articl decis addit phrase phrase justifi annex iv amend member state concern longer requir phrase member state entitl maintain requir time decis control measur articl member state make arrang plant protect product market offici check compli requir direct requir author inform appear label member state report annual august member state commiss result inspect measur previou year administr provis articl council act qualifi major propos commiss adopt uniform principl refer annex vi accord procedur laid articl regard current scientif technic knowledg amend annex ii iii iv vi adopt articl procedur laid articl matter refer delai chairman initi request member state stand committe plant health set decis eec herinaft refer committe repres commiss submit committe draft measur committe deliv opinion draft time limit chairman lai urgenc matter opinion deliv major laid articl treati vote repres member state committe weight manner set articl chairman vote commiss adopt measur envisag accord opinion committe measur envisag accord opinion committe opinion deliv commiss delai submit council propos relat measur council act qualifi major expiri period month date referr council council act propos measur adopt commiss articl procedur laid articl matter refer chairman initi request member state committe repres commiss submit committe draft measur committe deliv opinion draft time limit chairman lai urgenc matter take vote commiss adopt measur envisag accord opinion committe measur envisag accord opinion committe opinion deliv commiss delai submit council propos relat measur council act qualifi major expiri period dai date referr council council act propos measur adopt commiss articl procedur laid articl matter refer chairman initi request member state committe repres commiss submit committe draft measur committe deliv opinion draft time limit chairman lai urgenc matter take vote opinion record minut addit member state posit record minut commiss utmost account opinion deliv committe inform committe manner opinion account research develop articl member state prescrib experi test research develop purpos involv releas environ unauthor plant protect product carri author trial purpos grant control condit limit quantiti area person concern submit applic compet author member state territori experi test conduct time period prescrib member state commenc experi test dossier data permit assess made effect human anim health impact environ propos experi test refer paragraph liabl harm effect human anim health unaccept advers influenc environ member state concern prohibit permit subject condit consid prevent consequ paragraph appli member state grant person concern undertak experi test determin condit experi test undertaken common condit applic articl maximum quantiti pesticid releas experi cover paragraph minimum data submit accord paragraph adopt accord procedur laid articl articl appli experi test cover part direct eec implement direct articl member state bring forc law regul administr provis compli direct year notif thereof immedi inform commiss thereof uniform principl adopt year date notif member state adopt measur refer direct accompani refer occas offici public method make refer laid member state paragraph notwithstand member state bring forc law regul administr provis implement articl indent year latest adopt uniform principl relat requir articl cover uniform principl adopt articl direct address member state brussel juli council presid bukman oj oj oj oj oj annex activ substanc author incorpor plant protect product annex ii requir dossier submit inclus activ substanc annex introduct inform includ technic dossier suppli inform evalu forese risk delai substanc entail human environ inform result studi refer detail full descript studi conduct method bibliograph refer propos classif label substanc accord direct eec piec inform ow natur substanc propos suppli case scientif technic suppli inform justif accept commiss accord articl submit test conduct method annex direct eec event method inappropri method justifi test conduct accord requir direct eec principl laid direct eec part chemic substanc ident activ substanc applic address manufactur address includ locat plant common propos iso accept synonym chemic iupac nomenclatur manufactur develop code number ca eec number empir structur formula molecular mass method manufactur synthesi pathwai activ substanc specif puriti activ substanc kg ident isom impur addit stabil structur formula rang express kg oj substanc mean definit articl point physic chemic properti activ substanc melt point boil point rel densiti vapour pressur pa oc volatil henri law constant appear physic state colour odour threshold concentr substanc intens odour tast water absorpt spectra uv vi ir nmr ms molecular extinct relev wavelength solubl water includ effect ph temperatur solubl solubl organ solvent includ effect temperatur solubl partit coeffici octanol water includ effect ph temperatur stabil water hydrolysi rate photochem degrad quantum yield ident breakdown product dissoci constant includ effect ph stabil air photochem degrad ident breakdown product stabil organ solvent prepar thermal stabil ident breakdown product flammabl includ auto flammabl ident combust product flash point surfac tension explos properti oxid properti reactiv contain materi inform activ substanc function fungicid herbicid insecticid repel growth regul effect harm organ contact poison inhal poison stomach poison fungitox fungistat system plant field envisag field glasshous food feed storag home garden light test result specif agricultur plant health environment condit activ substanc harm organ control crop product protect treat mode action inform occurr occurr develop resist manag strategi recommend method precaut handl storag transport fire case fire natur reaction product combust gase data submit purifi activ substanc state specif data submit activ substanc purifi activ substanc state specif emerg measur case accid procedur destruct decontamin activ substanc possibl recoveri possibl neutral control discharg control inciner water purif analyt method analyt method determin pure activ substanc relev breakdown product isom impur activ substanc addit stabil analyt method includ recoveri rate limit determin residu relev treat plant plant product foodstuff feedingstuff soil water includ drink water air anim human bodi fluid tissu toxicolog metabol studi activ substanc acut toxic oral percutan inhal intraperiton skin ey irrit skin sensit short term toxic oral cumul toxic dai studi oral administr speci rodent prefer rat rodent dai studi rout inhal percutan chronic toxic oral long term toxic carcinogen rat mammalian speci rout mutagen test batteri assess gene mutat chromosom aberr dna perturb reproduct toxic teratogen studi rabbit rodent speci oral percutan multigener studi mammal gener metabol studi mammal absorpt distribut excret studi oral percutan administr elucid metabol pathwai neurotox studi includ delai neurotox test adult hen supplementari studi toxic effect metabolit treat plant case identifi anim studi mechanist studi need clarifi effect report toxic studi toxic effect livestock pet medic data medic surveil manufactur plant personnel direct observ clinic case poison incid health record industri agricultur observ exposur gener popul epidemiolog studi diagnosi poison determin activ substanc metabolit specif sign poison clinic test sensit allergen observ propos treatment aid measur antidot medic treatment prognosi expect effect poison summari mammalian toxicolog conclus includ observ advers effect level noael observ effect level noel accept daili intak adi evalu regard toxicolog data inform activ substanc residu treat product food feed identif breakdown reaction product metabolit treat plant product behaviour residu activ substanc metabolit time applic harvest outload store product uptak distribut relev plant kinet disappear bind plant constitu materi balanc activ substanc suffici residu data supervis trial demonstr residu aris propos treatment concern human anim health estim potenti actual exposur diet mean residu monitor data product distribut chain data exposur air water feed metabol studi livestock residu remain crop part crop feed permit evalu residu foodstuff anim origin effect industri process household prepar natur magnitud residu summari evalu residu behaviour result data submit pursuant point fate behaviour environ fate behavoir soil rate rout degrad cent degrad includ identif process involv identif metabolit breakdown product soil type condit adsorpt desorpt soil type relev adsorpt desorpt metabolit breakdown product mobil soil type relev mobil metabolit breakdown product extent natur bound residu fate behaviour water air rate rout degrad aquat system biodegrad hydrolysi photolysi cover point includ identif metabolit breakdown product adsorpt desorpt water sediment relev adsorpt desorpt metabolit breakdown product rate rout degrad air fumig volatil activ substanc cover point ecotoxicolog studi activ substanc effect bird acut oral toxic short term toxic dai dietari studi speci chicken effect reproduct effect aquat organ acut toxic fish chronic toxic fish effect fish reproduct growth rate bioaccumul fish acut toxic daphnia magna daphnia magna reproduct growth rate effect algal growth effect target organ acut toxic honeybe benefici arthropod predat toxic earthworm soil target macro organ effect soil target micro organ effect target organ flora fauna believ risk effect biolog method sewag treatment summari evalu point propos includ justif propos classif label activ substanc council direct eec hazard symbol indic danger risk phrase safeti phrase dossier refer annex iii part repres plant protect product part micro organ virus part appli gmo point direct eec ident organ applic address manufactur address includ locat plant common altern supersed name taxonom strain bacteria protozoa fungi indic stock variant mutant strain virus taxonom design agent serotyp strain mutant collect cultur refer number cultur deposit test procedur criteria identif morpholog biochemistri serolog composit microbiolog puriti natur ident properti content impur extran organ biolog properti organ target organ pathogen kind antagon host infect dose transmiss inform mode action histori organ natur occurr geograph distribut host specif rang effect speci target harm organ includ speci close relat target speci includ infect pathogen transmiss infect physic stabil propos method effect temperatur exposur air radiat persist environment condit organ close relat plant pathogen pathogen vertebr speci target invertebr speci laboratori evid genet stabil mutat rate environment condit propos presenc absenc product toxin natur ident chemic structur stabil inform organ function fungicid herbicid insecticid repel growth regul effect harm organ contact poison inhal poison stomach poison fungitox fungistat system plant field envisag field glasshous food feed storag home garden light test result specif agricultur plant health environment condit activ substanc harm organ control crop product protect treat method product descript techniqu ensur uniform product assai method standard case mutant detail inform provid product isol differ mutant parent wild strain method prevent loss virul seed stock recommend method precaut handl storag transport fire possibl render organ uninfect analyt method method establish ident puriti seed stock batch produc result obtain includ inform variabl method show microbiolog puriti final product show contamin control accept level result obtain inform variabl method show human mammalian pathogen contamin activ agent includ case protozoa fungi effect temperatur oc relev temperatur method determin viabl viabl toxin residu treat product foodstuff feedingstuff anim human bodi fluid tissu soil water air relev toxicolog pathogen infect studi bacteria fungi protozoa mycoplasma toxic pathogen infect oral singl dose case singl dose assess pathogen set rang find text carri reveal highli toxic agent infect percutan singl dose inhal singl dose intraperiton singl dose skin ey irrit skin sensit short term toxic dai exposur oral administr rout inhal percutan supplementari toxicolog pathogen infect studi oral long term toxic carcinogen mutagen test refer point part teratogen studi multigener studi mammal gener metabol studi absorpt distribut excret mammal includ elucid metabol pathwai neurotox studi includ delai neurotox test adult hen immunotox allergen pathogen infect immunosuppress virus viroid acut toxic pathogen infect data outlin point cell cultur studi purifi infect viru primari cell cultur mammalian avian fish cell short term toxic data outlin point test infect carri bio assai suitabl cell cultur dai administr test anim supplementari toxicolog pathogen infect studi outlin point toxic effect livestock pet medic data medic surveil manufactur plant personnel health record industri agricultur observ exposur gener popul epidemiolog data diagnosi poison specif sign poison clinic test sensit allergen observ propos treatment aid measur antidot medic treatment prognosi expect effect poison summari mammalian toxicolog conclus includ noael noel adi evalu regard toxicolog pathogen infect data infect inform activ substanc residu treat product food feed identif viabl viabl toxin residu treat plant product viabl residu cultur bio assai viabl techniqu likelihood multipl activ substanc crop food report effect food qualiti case residu toxin remain edibl plant product data outlin point part requir summari evalu residu behaviour result data submit point fate behaviour environ spread mobil multipl persist air water soil inform fate food chain case toxin produc data outlin part point requir relev ecotoxicolog studi bird acut oral toxic pathogen infect fish acut toxic pathogen infect toxic daphnia magna effect algal growth import parasit predat target speci acut toxic pathogen infect honei bee acut toxic pathogen infect earthworm acut toxic pathogen infect target organ believ risk acut toxic pathogen infect extent indirect contamin adjac target crop wild plant soil water effect flora fauna case toxin produc data outlin part point requir relev summari evalu point propos includ justif propos classif label activ substanc accord direct eec hazard symbol indic danger risk phrase safeti phrase dossier refer annex iii part repres plant protect product annex iii requir dossier submit author plant protect product introduct inform requir includ technic dossier suppli inform evalu efficaci forese risk delai plant protect product entail human environ inform result studi refer detail full descript studi conduct method bibliograph refer propos classif label plant protect product accord relev commun direct individu case requir inform provid annex ii part formul solvent synergist piec inform ow natur product propos suppli case scientif technic suppli inform justif accept compet author submit test conduct method annex direct eec event method inappropri method justifi test conduct accord requir direct eec principl laid direct eec part chemic prepar ident plant protect product applic address manufactur prepar activ substanc name address includ locat plant trade propos trade manufactur develop code number prepar detail quantit qualit inform composit prepar activ substanc impur adjuv inert compon physic state natur prepar emulsifi concentr wettabl powder solut categori herbicid insecticid physic chemic technic properti plant protect product appear colour odour explos oxid properti flash point indic flammabl spontan ignit acid alkalin ph water viscos surfac tension rel densiti storag stabil stabil shelf life effect light temperatur humid technic characterist plant protect product technic characterist plant health product wettabl persist foam suspens suspens stabil wet siev test dry siev test particl size distribut content dust fine attrit friabil case granul siev test indic weight distribut granul fraction particl size bigger mm content activ substanc bait particl granul treat seed emulsifi emulsifi emuls stabil flowabl pourabl dustabl physic chemic compat product includ plant protect product author wet adher distribut target plant data applic field field glasshous food feed storag home garden effect harm organ contact poison inhal poison stomach poison fungitox fungistat system plant detail intend type harm organ control plant plant product protect light test result specif agricultur plant health environment condit organ applic rate concentr activ substanc materi dilut sprai bait treat seed method applic number time applic durat protect wait period precaut avoid phytotox effect succeed crop propos instruct inform plant protect product packag type materi size compat prepar propos packag materi procedur clean applic equip entri period wait period precaut protect human anim recommend method precaut handl storag transport fire emerg measur case accid ident combust product relev case fire procedur destruct decontamin plant protect product packag possibl neutral control discharg control inciner water purif analyt method analyt method determin composit plant protect product cover annex ii part point analyt method includ recoveri rate limit determin residu relev treat plant plant product foodstuff feedingstuff soil water includ drink water air anim human bodi fluid tissu efficaci data preliminari rang find test field experiment inform occurr develop resist effect qualiti yield treat plant effect qualiti treat plant product phytotox target plant includ cultivar target plant product observ undesir unintend side effect benefici target organ succeed crop plant part treat plant propag purpos seed cut runner summari evalu data present point toxicolog studi acut toxic oral percutan inhal skin relev ey irrit skin sensit acut dermal toxic skin ey irrit combin plant protect product author sought combin oper exposur dermal absorpt oper exposur field condit includ relev quantit analysi oper exposur toxicolog data relat activ substanc residu treat product food feed data supervis trial crop food feedingstuff author sought give experiment condit detail includ residu data activ substanc relev metabolit relev constitu plant protect product time applic harvest case post harvest treatment breakdown residu storag level residu time releas storag market data rang climat agronom condit encount propos area effect industri process household prepar natur magnitud residu effect taint odour tast qualiti aspect due residu fresh process product estim residu product anim origin result ingest feedingstuff result contact bed basi residu data refer point studi livestock refer annex ii part point residu data succeed rotat crop presenc residu expect propos pre harvest interv envisag withold period storag period case post harvest propos maximum residu level mrl justif accept residu summari evalu residu behaviour basi data submit point fate behaviour environ inform provid relev includ refer annex ii part point test distribut dissip soil test distribut dissip water test distribut dissip air ecotoxicolog studi effect bird acut oral toxic supervis trial assess risk avian speci field condit studi accept bait granul treat seed bird effect aquat organ acut toxic fish acut toxic daphnia magna oversprai studi toxic fish aquat organ persist water assess risk aquat organ field condit case applic surfac water studi fish aquat organ residu data fish activ substanc includ toxicolog relev metabolit studi refer annex ii part point requir plant protect product effect target organ effect terrestri vertebr bird toxic honei bee toxic forag bee field condit effect benefici arthropod bee effect earthworm soil target macro organ believ risk effect soil target micro organ data biolog primari screen summari form summari evalu point inform inform author countri inform establish maximum residu limit mrl countri propos includ justif classif label propos accord direct eec direct eec hazard symbol indic danger risk phrase safeti phrase propos risk safeti phrase accord articl propos label specimen propos packag part prepar micro organ virus part appli gmo point direct eec ident plant protect product applic address manufactur prepar activ agent name address includ locat plant trade propos trade manufactur develop code number plant protect product detail quantit qualit inform composit plant protect product activ organ inert compon extran organ physic state natur plant protect product emulsifi concentr wettabl powder categori insecticid fungicid technic properti plant protect product appear colour odour storag stabilitii stabil shelf life effect temperatur method packag storag retent biolog activ method establish storag shelf life stabil technic characterist prepar wettabl persist foam suspens suspens stabil wet siev test dry siev test particl size distribut content dust fine attrit friabil case granul siev test indic weight distribut granul fraction particl size bigger mm content activ substanc bait particl granul treat seed emulsifi emulsifi emuls stabil flowabl pourabl dustabl physic chemic compat product includ plant protect product author wet adher distribut target plant data applic field field glasshous food feed storag home garden detail intend type harm organ control plant plant product protect applic rate light test result specif agricultur plant health environment condit product concentr activ substanc materi concentr dilut sprai method applic number time applic phytopathogen propos instruct inform prepar packag type materi size compat prepar propos packag materi procedur clean applic equip entri period wait period precaut protect human anim recommend method precaut handl storag transport emerg measur case accid procedur destruct decontamin plant protect product packag analyt method analyt method determin composit plant protect product method determin residu treat plant plant product biotest method show microbiolog puriti plant protect product method show plant protect product free human mammalian pathogen honei bee pathogen techniqu ensur uniform product assai method standard efficaci data preliminari rang find test field experiment inform occurr develop resist effect qualiti yield treat plant effect qualiti treat plant product phytotox target plant includ cultivar target plant product observ undesir unintend side effect benefici target organ succeed crop plant part treat plant propag purpos seed cut runner summari evalu data present point toxic pathogen infect studi oral singl dose percutan singl dose inhal skin relev ey irrit skin sensit toxicolog data relat activ substanc oper exposur percutan absorpt oper exposur field condit includ relev quantit analysi oper exposur residu treat product food feed residu data activ substanc includ data supervis trial crop food feedingstuff author sought give experiment condit detail data rang climat agronom condit encount propos area identifi viabl viabl residu treat crop effect industri process household prepar natur magnitud residu effect taint odour tast qualiti aspect due residu fresh process product residu data product anim origin result ingest feedingstuff contact bed residu data succeed rotat crop presenc residu expect propos pre harvest interv envisag withold period storag period case post harvest propos maximum residu level mrl justif accept level toxin summari evalu residu behaviour basi data submit point fate behaviour environ case toxin produc data outlin part point requir ecotoxicolog studi effect aquat organ fish studi daphnia magna speci close relat target organ studi aquat micro organ effect benefici target organ effect honei bee effect benefici organ effect earthworm effect soil fauna effect target organ believ risk effect soil microflora summari evalu point inform inform author countri inform establish maximum residu limit mrl countri propos includ justif classif label propos accord direct eec eec hazard symbol indic danger risk phrase safeti phrase propos risk safeti phrase accord articl propos label specimen propos packag annex iv risk phrase annex safeti phrase annex vi uniform principl evalu plant protect product