commiss direct ec juli amend council direct eec place plant protect product market text eea relev commiss european commun regard treati establish european commun regard council direct eec juli place plant protect product market amend commiss direct ec articl thereof annex ii iii direct eec provid requir dossier submit applic inclus activ substanc annex author plant protect product annex ii iii direct eec applic precis detail requir inform circumst condit technic protocol data gener provis introduc order permit applic prepar file introduc precis regard data requir fate behaviour environ activ substanc provid annex ii part section introduc precis regard data requir fate behaviour environ plant protect product provid section part annex iii part section measur provid direct accord opinion stand committe plant health adopt direct articl direct eec amend part annex ii section head fate behaviour environ replac annex hereto part annex iii section head fate behaviour environ replac annex ii hereto articl member state bring forc law regul administr provis compli april provis direct immedi inform commiss thereof member state adopt measur refer direct accompani refer time offici public procedur refer adopt member state articl direct enter forc juli articl direct address member state brussel juli commiss ritt bjerregaard member commiss annex fate behaviour environ introduct inform provid prepar activ substanc suffici pemit assess fate behaviour activ substanc environ target speci risk exposur activ substanc metabolit degrad reaction product toxicolog environment signific ii inform provid activ substanc relev inform provid prepar suffici decid activ substanc includ annex condit restrict inclus annex classifi activ substanc hazard hazard symbol indic danger relev risk safeti phrase protect environ includ packag contain predict disribut fate behaviour environ activ substanc relev metabolit degrad reaction product time cours involv identifi target speci popul hazard rise potenti exposur identifi measur necesari minim contamin environ impact target speci iii detail descript specif materi provid section point provid test activ substanc materi specif manufactur prepar author radio label materi studi conduct activ substanc produc laboratori pilot plant product system studi repeat activ substanc manufactur justifi test materi essenti purpos environment test assess iv radio label test materi radio label posit site facilit elucid metabol degrad pathwai facilit investig distribut activ substanc metabolit reaction degrad product environ conduct separ studi metabolit degrad reaction product product constitut relev risk target organ qualiti water soil air effect evalu result relat activ substanc studi perform inform section account vi relev test design data analys statist method full detail statist anaylsi report point estim confid interv exact valu state signific signific fate behaviour soil relev inform type properti soil studi includ ph organ carbon content cation exchang capac particl size distribut water hold capac particl size distribut water hold capac pf pf report accord relev iso intern standard microbi biomass soil laboratori degrad studi determin prior commenc end studi recommend soil laboratori soil studi soil degrad mobil studi select repres rang soil typic commun region exist anticip cover rang organ carbon content particl size distribut ph valu basi inform degrad mobil expect ph depend solubl hydrolysi rate paragraph cover ph rang approxim soil freshli sampl store soil unavoid storag properli carri limit time defin report condit soil store longer period time adsorpt desorpt studi soil chosen begin studi extrem characterist respect paramet particl size distribut organ carbon content ph soil collect handl accord iso soil qualiti sampl guidanc collect handl storag soil assess microbi process laboratori deviat report justifi field studi carri condit close normal agricultur practic rang soil type climat condit repres area weather condit report case field studi conduct rout rate degrad rout degrad aim test data inform provid relev data inform suffici identifi feasabl rel import type process involv balanc chemic biolog degrad identifi individu compon present time account amount activ substanc ad includ feasibl extract residu identifi individu compon present account amount activ substanc ad establish rel proport compon present mass balanc permit soil residu concern target speci expos defin refer made extract residu defin chemic speci origin pesticid good agricultur practic extract method significantli chang chemic natur residu extract residu consid includ fragment metabol pathwai lead natur product aerob degrad circumst requir degrad pathwai pathwai report natur manner prepar activ substanc preclud soil contamin store product wound heal treatment tree test condit degrad pathwai pathwai report soil result obtain present form schemat draw show pathwai involv form balanc sheet show distribut radio label function time activ substanc volatil compound individu identifi transform product extract substanc identifi extract residu soil investig degrad pathwai includ feasibl step characteris quantifi extract residu form dai exceed appli dose activ substanc techniqu methodolog appli select case case basi justif provid compound involv character durat studi dai shorter period level extract residu extrapol reliabl dai test guidelin setac procedur assess environment fate ecotox pesticid supplementari studi anaerob degrad circumst requir anaerob degrad studi report justifi exposur plant protect product activ substanc anaerob condit occur test condit test guidelin provis provid paragraph point appli soil photolysi circumst requir soil photolysi studi report justifi deposit activ substanc soil surfac occur test guidelin setac procedur assess environment fate ecotox pesticid rate degrad laboratori studi aim test soil degrad studi provid estim time degrad dt lab dt lab activ substanc relev metabolit degrad reaction product laboratori condit aerob degrad circumst requir rate degrad soil report natur manner plant protect product activ substanc preclud soil contamin store product wound heal treatment tree test condit rate aerob degrad activ substanc soil type addit refer paragraph report order investig influenc temperatur degrad addit studi perform soil investig degrad valid commun calcul model extrapol degrad rate low temperatur durat studi dai activ substanc degrad period expir similar studi soil type report relev metabolit degrad reaction product occur soil time studi account amount activ substanc ad dt valu determin result degrad studi activ substanc test guidelin setac procedur assess environment fate ecotox pesticid anaerob degrad circumst requir rate anaerob degrad activ substanc report anaerob studi perform point test condit rate anaerob degrad activ substanc carri soil anaerob studi perform point durat studi dai activ substanc degrad period expir similar studi soil report relev metobolit degrad reaction product occur soil time studi account amount activ substanc ad dt valu determin result degrad studi activ substanc test guidelin setac procedur assess environment fate ecotox pesticid field studi soil dissip studi aim test soil dissip studi provid estim time dissip dt dt activ substanc field condit relev inform relev metabolit degrad reaction product report circumst requir plant protect product activ substanc intend cold climat condit test conduct dt lab determin moistur content soil relat pf suction pressur greater dai test condit individu studi rang repres soil type continu gt amount appli dissip maximum durat studi month test guidelin setac procedur assess environment fate ecotox pesticid soil residu studi aim test soil residu studi provid estim soil residu level harvest time cow plant succeed crop circumst requir soil residu studi report dt lab greater period applic harvest absorpt succeed crop soil residu sow plant succeed crop reliabl estim data soil dissip studi justifi residu phytotox leav unaccept residu rotat crop test condit individu studi continu harvest time sow plant succeed crop gt amount appli dissip test guidelin setac procedur assess environment fate ecotox pesticid soil accumul studi aim test test provid suffici data evalu possibl accumul residu activ substanc relev metabolit degrad reaction product circumst requir basi soil dissip studi establish dt gt year repeat applic envisag grow season succeed year possibl accumul residu soil level plateau concentr achiev investig reliabl inform provid model calcul assess test condit long term field studi relev soil involv multipl applic perform studi applic seek agreement compet author type studi perform adsorpt desorpt aim test data inform provid relev data inform suffici establish absorpt coeffici activ substanc relev metabolit degrad reaction product circumst requir studi report natur manner prepar activ substanc preclud soil contamin store product wound heal tree testo condit studi activ substanc report soil type similar studi soil type report relev metabolit degrad reaction product soil degrad studi account time amount activ substanc ad test guidelin oecd method mobil soil column leach studi aim test test provid suffici data evalu mobil leach potenti activ substanc relev metabol degrad reaction product circumst requir studi soil carri absorpt desorpt studi provid point obtain reliabl absorpt coeffici valu test guidelin setac procedur assess environment fate ecotox pesticid ag residu column leach aim test test provid suffici data estim mobil leach potenti relev metabolit degrad reaction product circumst requir studi perform natur manner prepar activ substanc preclud soil contamin store product wound heal treatment tree separ studi metabolit degrad reaction product accord point perform test condit period ag determin inspect degrad pattern activ substanc metabolit ensur relev spectrum metabolit present time leach test guidelin setac procedur assess environment fate ecotox pesticid lysimet studi field leach studi aim test test provid data mobil soil potenti leach ground water potenti distribut soil circumst requri expert judgement decid lysimet studi field leach studi carri take account result degrad mobil studi predict environment concentr groundwat pecgw calcul accord provis annex iii section type condit studi conduct discuss compet author test condit great care design experiment instal individu studi ensur result obtain assess purpos studi cover realist worst case situat take account soil type climat condit applic rate frequenc period applic water percol soil column analyz suitabl interv residu plant materi determin harvest residu soil profil layer determin termin experiment work intermedi sampl avoid remov plant harvest normal agricultur practic soil cross influenc leach process precipit soil air temperatur record regular interv weekli base lysimet studi test condit minim depth lysimet cm maxim depth cm soil cross undisturb soil temperatur similar pertain field supplementari irrig provid ensur optim plant growth ensur quantiti infiltr water similar region author sought studi soil disturb agricultur reason disturb deeper cm field leach studi test condit inform groundwat tabl experiment field submit soil crack observ studi fulli great attent number locat water collect devic placement devic soil result preferenti flow path test guidelin setac procedur assess environment fate ecotox pesticid fate behaviour water air aim test inform data provid provid prepar activ substanc relev inform suffici establish permit estim persist water system bottom sediment water includ suspend particl extent water sediment organ air risk potenti contamin surfac water groundwat rout rate degrad aquat system cover point aim test data inform provid relev data inform suffici identifi rel import type process involv balanc chemic biolog degrad identifi individu compon present establish rel proport compon present distribut water includ suspend particl sediment permit residu concern target speci expos defin hydrolyt degrad circumst requir test perform relev metabolit degrad reaction product account time amount activ substanc ad suffici inform degrad test perform accord point test condit test guidelin provis provid paragraph point appli photochem degrad circumst requir test perform relev metabolit degrad reaction product account time amount activ substanc ad suffici inform degrad test perform accord point test condit test guidelin provis provid paragraph point appli biolog degrad quot readi biodegrad quot circumst requir test perform requir provis annex vi direct eec classif activ substanc test guidelin eec method water sediment studi circumst requir test report justifi contamin surfac water occur test guidelin setac procedur assess environment fate ecotox pesticid degrad satur zone circumst requir transform rate satur zone activ substanc relev metabolit degrad reaction product provid inform fate substanc groundwat test condit expert judgement requir decid inform perform studi applic seek agreement compet author type studi perform rout rate degrad air cover point guidanc develop definit residu light chemic composit residu occur soil water air result propos plant protect product activ substanc propos definit residu submit take account level found toxicolog environment signific monitor data monitor data fate behaviour activ substanc relev metabolit degrad reaction product report annex ii fate behaviour environ introduct inform provid activ substanc provid annex ii suffici permit assess fate behaviour plant protect product environ target speci risk exposur ii inform provid plant protect product relev inform provid activ substanc suffici hazard symbol indic danger relev risk safeti phrase protect environ includ packag contain predict distribut fate behaviour environ time cours involv identifi target speci popul hazard aris potenti exposur identifi measur minim contamin environ impact target speci iii radio label test materi provis annex ii chapter introduct point iv appli iv relev test design data analys statist method full detail statist analysi report point estim confid interv exact valu state signific signific predict environment concentr soil pec water pecsw pecgw air peca justifi estim made expect concentr activ substanc relev metabolit degrad reaction product soil groundwat surfac water air propos occur addit realist worst case estim made purpos estim concentr definit appli predict environment concentr soil pec level residu top layer soil target soil organ expos acut chronic exposur predict environment concentr surfac water pecsw level residu surfac water target aquat organ expos acut chronic exposur predict environment concentr groundwat pecgw level residu groundwat predict environment concentr air peca level residu air man anim target organ expos acut chronic exposur estim concentr relev inform plant protect product activ substanc account approach estim provid eppo scheme environment risk assess relev paramet provid section model estim predict environment concentr make estim relev process involv take account realist paramet assumpt reliabl valid measur carri circumst relev model relev condit area inform provid relev includ refer annex ii part point fate behaviour soil provis relat inform provid soil select appli provid annex ii point rate degrad soil laboratori studi aim test soil degrad studi provid estim time degrad dt lab dt lab activ substanc laboratori condit circumst requir persist behaviour plant protect product soil investig extrapol data obtain activ substanc relev metabolit degrad reaction product accord requir annex ii point extrapol slow releas formul test condit rate aerob anaerob degrad soil report durat studi dai activ substanc degrad period expir test guidelin setac procedur assess environment fate ecotox pesticid field studi soil dissip studi aim test soil dissip studi provid estim time dissip dt dt activ substanc field condit relev inform relev metabolit degrad reaction product collect circumst requir dissip behaviour plant protect product soil investig extrapol data obtain activ substanc relev metabolit degrad reaction product accord requir annex ii point extrapol slow releas formul test condit test guidelin provis provid paragraph annex ii point appli soil residu studi aim test soil residu studi provid estim soil residu level harvest time sow plant succeed crop circumst requir soil residu studi report extrapol data obtain activ substanc relev metabolit degrad reaction product accord requir annex ii point extrapol slow releas formul test condit provis provid paragraph annex ii point appli test guidelin setac procedur assess environment fate ecotox pesticid soil accumul studi aim test test provid suffici data evalu possibl accumul residu activ substanc relev metabolit degrad reaction product circumst requir soil accumul studi report extrapol data obtain activ substanc relev metabolit degrad reaction product accord requir annex ii point extrapol slow releas formul test condit provis provid paragraph annex ii point appli test guidelin setac procedur assess environment fate ecotox pesticid mobil soil aim test test provid suffici data evalu mobil leach potenti activ substanc relev metabolit degrad reaction product laboratori studi circumst requir mobil plant protect product soil investig extrapol data obtain accord requir annex ii point extrapol slow releas formul test guidelin setac procedur assess environment fate ecotox pesticid lysimet studi field leach studi aim test test provid data mobil plant protect product soil potenti leach ground water potenti distribut soil circumst requir expert judgement decid field leach studi lysimet studi carri take account result degrad mobil studi calcul pec type studi conduct discuss compet author studi perform extrapol data obtain activ substanc relev metabolit degrad reaction product accord requir annex ii point extrapol slow releas formul test condit provis provid paragraph annex ii point appli estim expect concentr soil pec estim relat singl applic highest rate applic author sought maximum number highest rate applic author sought relev soil test express term mg activ substanc relev metabolit degrad reaction product kg soil factor consid make pec estim relat direct indirect applic soil drift run leach includ process volatil adsorpt hydrolysi photolysi aerob anaerob degrad purpos pec calcul bulk densiti soil assum cm dry weight depth soil layer assum cm applic soil surfac cm incorpor soil involv ground cover present time applic assum minimum appli dose reach soil surfac actual experiment data give specif inform initi short term long term pec calcul time weight averag provid initi immedi applic short term hour dai dai applic long term dai applic relev fate behaviour water estim concentr groundwat groundwat contamin rout defin take account relev agricultur plant health environment includ climat condit suitabl estim calcul predict environment concentr groundwat pecgw activ substanc relev metabolit degrad reaction product submit pec estim relat maximum number highest rate applic author sought expert judgment requir decid addit field test provid inform perform studi applic seek agreement compet author type studi perform impact water treatment procedur case inform framework condit author meant annex vi part point inform provid permit establish estim effect water treatment procedur drink water sewag treatment impact procedur perform studi applic seek agreement compet author type inform provid estim concentr surfac water surfac water contamin rout defin take account relev agricultur plant health environment includ climat condit suitabl estim calcul predict environment concentr surfac water pecsw activ substanc relev metabolit degrad reaction product submit pec estim relat maximum number highest rate applic author sought relev lake pond river canal stream irrig drainag canal drain factor consid make pecsw estim relat direct applic water drift run discharg drain atmospher deposit includ process volatil adsorpt advect hydrolysi photolysi biodegrad sediment suspens initi short term long term pecsw calcul relev static slow move water bodi time weight averag provid initi immedi applic short term hour dai dai applic long term dai applic relev expert judgment requir decid addit field test provid inform perform studi applic seek agreement compet author type studi perform fate behaviour air guidanc develop