commiss regul ec june amend annex iii xi regul ec european parliament council epidemio surveil test transmiss spongiform encephalopathi commiss european commun regard treati establish european commun regard regul ec european parliament council lai rule prevent control erad transmiss spongiform encephalopathi articl thereof detail rule monitor transmiss spongiform encephalopathi tse bovin ovin caprin anim laid annex iii regul ec rule includ systemat test bovin anim month ag enter food chain random test bovin anim month ag enter food chain addit bovin anim subject casualti slaughter found sick slaughter destruct thirti month scheme otm test ovin caprin anim clinic sign compat tse subject activ surveil view detect bovin spongiform encephalopathi bse bovin anim ag month routin test casualti slaughter anim provid earli warn system emerg unfavour trend bse incid younger anim ag limit reduc month anim belong risk popul monitor carri trimest posit bse case detect member state greec luxembourg austria finland sweden number bovin anim belong risk group test member state greec luxembourg austria finland sweden opinion juli geograph risk bse gbr scientif steer committe ssc conclud gbr level luxembourg iii bse confirm low level gbr level austria finland sweden ii bse exclud greec submit dossier assess refer legal technic uncertainti light monitor carri austria finland sweden assess ssc presenc bse member state exclud present bse detect examin bovin anim di farm subject casualti slaughter found sick normal slaughter member state allow reduc test healthi slaughter bovin anim view addit inform occurr bse unit kingdom test otm expand includ anim born year effect enforc feed ban bovin anim slaughter otm test random member state allow test bovin anim voluntari basi anim consid present higher risk provid disrupt trade clarifi measur test bovin anim introduc measur prevent carcas potenti contamin test posit carcas enter food chain rapid post mortem test introduc random basi improv detect scrapi ovin caprin anim obtain complet pictur situat carri random sampl target popul dead farm anim slaughter anim member state small nation herd sheep goat difficult carri statist meaning sampl target group member state allow smaller sampl size target anim likelihood find posit case highest view role genet resist develop clinic scrapi possibl breed programm prevent control erad scrapi genotyp scrapi case determin case found resist genotyp submit strain type list nation refer laboratori updat introduct rapid test monitor programm ovin caprin anim lai diagnost method protocol diagnost method protocol laid bovin anim updat articl regul ec conclus statist survei confirm overturn risk analysi conclus carri step determin bse statu countri region minimum criteria statist survei laid part annex xi view lower bse risk austria finland sweden assess ssc disproportion resourc involv derog provid member state exclud survei dead farm anim remot area low anim densiti interest clariti commiss decis ec epidemio surveil transmiss spongiform encephalopathi amend decis ec ec test bovin anim presenc bovin spongiform encephalopathi amend decis ec repeal measur provid regul accord opinion stand veterinari committe adopt regul articl regul ec amend text annex iii replac text annex regul text annex chapter point replac text annex ii regul text annex chapter replac text annex iii regul text annex xi chapter replac text annex iv regul articl decis ec ec repeal refer repeal decis constru refer regul ec refer annex iva decis ec constru refer annex chapter point regul ec articl regul enter forc dai public offici journal european commun appli juli provis annex iii chapter section ii regul ec set annex regul appli januari provis annex iii regul ec set annex regul review light result obtain month monitor regul bind entireti directli applic member state brussel june commiss david byrn member commiss oj oj oj oj annex quot annex iii monitor system chapter monitor bovin anim gener monitor bovin anim carri accord laboratori method laid annex chapter point monitor anim slaughter human consumpt bovin anim month ag subject quot special emerg slaughter quot defin articl council direct eec slaughter accord annex chapter vi point direct eec test bse bovin anim month ag subject normal slaughter human consumpt test bse derog point regard bovin anim born rear slaughter territori austria finland sweden decid examin random sampl sampl compris anim year monitor anim slaughter human consumpt bovin anim month ag di kill kill destruct pursuant commiss regul ec kill framework epidem foot mouth diseas slaughter human consumpt test bse random number sampl sampl size tabl sampl repres region continu gt tabl gt monitor anim purchas destruct pursuant regul ec anim subject casualti slaughter found sick ant mortem inspect test bse anim born august august test bse random sampl compris anim annual anim cover point test bse monitor anim addit test refer point member state voluntari basi decid test bovin anim territori anim origin countri indigen bse consum potenti contamin feedingstuff born deriv bse infect dam measur test anim slaughter human consumpt test bse health mark provid chapter xi annex direct eec carri carcas anim neg result rapid test obtain member state derog provis point offici system place slaughterhous ensur part examin anim bear health mark leav slaughterhous neg result rapid test obtain part bodi anim test bse includ hide retain offici control neg result rapid test obtain destroi accord annex point part bodi anim found posit rapid test includ hide destroi accord annex point materi retain conjunct record provid chapter section iii anim slaughter human consumpt found posit rapid test carcas immedi preced test posit carcas carcas immedi test posit carcas slaughter line destroi accord point addit test posit carcas member state derog provis point system place slaughterhous prevent contamin carcas ii monitor ovin caprin anim gener monitor ovin caprin anim carri accord laboratori method laid annex chapter point monitor anim slaughter human consumpt anim month ag slaughter human consumpt test accord sampl size tabl sampl repres region season sampl select design view avoid represent group origin speci ag breed product type characterist ag anim estim base dentit obviou sign matur reliabl inform multipl sampl flock avoid gt tabl gt monitor anim slaughter human consumpt anim month ag di kill kill framework epidem foot mouth diseas slaughter human consumpt test accord sampl size tabl sampl repres region season sampl select design view avoid represent group origin speci ag breed product type characterist ag anim estim base dentit obviou sign matur reliabl inform multipl sampl flock avoid gt tabl gt monitor member state small ovin caprin popul member state total number ovin caprin anim month ag derog sampl foreseen point decid monitor combin subpopul anim month ag di kill kill framework epidem foot mouth diseas slaughter human consumpt quot dead anim quot anim month ag appear suggest chronic wast condit quot chronic wast anim quot number sampl test annual member state combin subpopul sampl size tabl sampl repres region season sampl select design view avoid represent group origin speci ag breed product type characterist dead anim sampl ag anim estim base dentit obviou sign matur reliabl inform chronic wast anim sampl anim inspect offici veterinarian ag clinic symptom document select sampl multipl sampl flock avoid gt tabl gt monitor anim addit monitor programm set point member state voluntari basi carri monitor anim anim dairi product anim origin countri indigen tse anim consum potenti contamin feedingstuff anim born deriv tse infect dam anim flock infect tse measur test ovin caprin anim part bodi test anim includ hide retain offici control neg result rapid test obtain destroi accord annex point part bodi anim found posit rapid test includ hide destroi accord annex point materi retain conjunct record provid chapter section iii genotyp prion protein genotyp determin posit tse case sheep tse case found resist genotyp sheep genotyp encod alanin allel codon arginin allel codon arginin allel codon immedi report commiss case submit strain type strain type case herd origin herd anim subject enhanc monitor view find tse case strain type chapter inform present member state report number suspect case anim speci movement restrict accord articl number suspect case anim speci subject laboratori examin accord articl outcom examin number flock suspect case ovin caprin anim report investig pursuant articl estim size subpopul refer chapter section point number bovin anim test subpopul refer chapter section point method sampl select outcom test estim size subpopul refer chapter section ii point select sampl number ovin caprin anim flock test subpopul refer chapter section ii point method sampl select outcom test number ag distribut geograph distribut posit case bse scrapi countri origin report countri posit case bse scrapi number geograph distribut scrapi posit flock year month birth bse case posit tse case confirm anim bovin ovin caprin anim ii inform present commiss summari summari present tabl format cover inform refer part member state iii record compet author year record number type anim movement restrict refer articl number outcom clinic epidemiolog investig refer articl number outcom laboratori examin refer articl number ident origin anim sampl framework monitor programm refer chapter ag breed anamnest inform prion protein genotyp posit tse case sheep chronic wast ovin caprin anim select sampl method establish ag clinic symptom observ sampl anim investig laboratori year record test laboratori workbook paraffin block photograph western blot oj oj quot annex ii quot nation refer laboratori gt tabl gt quot annex iii quot chapter sampl laboratori test sampl sampl intend examin presenc tse collect method protocol laid latest edit manual standard diagnost test vaccin intern offic epizooti ioe oie hereinaft refer manual absenc method protocol sampl collect manner correct applic test sampl correctli mark ident sampl anim laboratori laboratori examin tse carri laboratori approv purpos method protocol laboratori test presenc bse bovin anim suspect case tissu bovin anim laboratori test pursuant provis articl subject histopatholog examin laid latest edit manual materi autolys result histopatholog examin inconclus neg materi autolys tissu subject examin diagnost method laid manual immunocytochemistri immuno blot demonstr characterist fibril electron microscopi rapid test purpos result examin posit anim regard posit bse case bse monitor tissu bovin anim laboratori test pursuant provis annex iii chapter section monitor bovin anim examin rapid test result rapid test inconclus posit tissu immedi subject confirmatori examin offici laboratori confirmatori examin start histopatholog examin brainstem laid latest edit manual materi autolys suitabl examin histopatholog result histopatholog examin inconclus neg materi autolys tissu subject examin diagnost method mention anim regard posit bse case result rapid test posit inconclus result subsequ histopatholog examin posit result diagnost method mention posit laboratori test presenc scrapi ovin caprin anim suspect case tissu ovin caprin anim laboratori test pursuant provis articl subject histopatholog examin laid latest edit manual materi autolys result histopatholog examin inconclus neg materi autolys tissu subject examin immunocytochemistri immuno blot laid manual rapid test purpos result examin posit anim regard posit scrapi case scrapi monitor tissu ovin caprin anim laboratori test pursuant provis annex iii chapter section ii monitor ovin caprin anim examin rapid test result rapid test inconclus posit brainstem immedi offici laboratori confirmatori examin immunocytochemistri immuno blot refer anim regard posit scrapi case result confirmatori examin posit laboratori test presenc tse refer point test carri confirm suspect presenc tse refer point includ histopatholog examin brain tissu compet author requir laboratori test immunocytochemistri immuno blot demonstr characterist fibril electron microscopi method design detect diseas form prion protein case laboratori examin carri initi histopatholog examin neg inconclus examin carri event appear diseas bse suspect speci bovin anim sampl submit strain type rapid test purpos carri test accord articl articl method rapid test mean regul immuno blot test base western blot procedur detect proteas resist fragment prpre prionic check test chemiluminesc elisa test involv extract procedur elisa techniqu enhanc chemiluminesc reagent enfer test sandwich immunoassai prpre carri denatur concentr step bio rad platelia test altern test defin quot annex iv quot statist survei statist survei refer articl cover anim sampl pursuant provis annex iii chapter section point anim subpopul refer annex iii chapter section point random sampl provis applic period year review light experi gain month austria finland sweden decid derog provis point indent remot area low anim densiti quot