commiss regul ec april implement regul ec european parliament council qualiti criteria valid analyt method sampl identif characteris primari smoke product commiss european commun regard treati establish european commun regard regul ec european parliament council novemb smoke flavour intend food articl thereof regul ec lai provis establish list primari product authoris food product smoke flavour food commun list thing clear descript characteris primari product detail inform qualit quantit chemic composit primari product scientif evalu portion identifi amount substanc chemic structur small establish minimum perform criteria context refer qualiti criteria method analysi compli order ensur laboratori method level perform smoke food gener give rise health concern respect presenc polycycl aromat hydrocarbon pah person intend place primari product market submit inform safeti assess inform propos valid method sampl identif characteris primari product regul ec european parliament council april offici control perform ensur verif complianc feed food law anim health anim welfar rule lai gener requir method sampl analysi scientif committe food scf name pah potenti genotox carcinogen human opinion risk human health pah food express decemb repres prioriti group assess risk long term advers health effect dietari intak pah presenc primari product consequ analys institut refer materi measur irmm commiss director gener joint research centr carri collabor studi analys chemic composit primari product quantifi concentr pah result trial part publish report collabor trial valid method quantif polycycl aromat hydrocarbon primari smoke condens describ precis method repeat standard deviat defin iso requir estim data singl laboratori valid exercis give si harmon guidelin singl laboratori valid method analysi collabor trial give sr sr protocol design conduct interpret method perform studi full valid method analys composit primari product maximum compound identifi achiev high number analyt rise incalcul amount work impract mass spectrometri detect compound result mass spectra compar publish data mass spectral librari tent identif compound achiev base result obtain inter laboratori valid studi pah commiss decis ec minimum qualiti criteria suitabl analyt method determin pah primari product propos recommend iso iupac aoac intern harmon guidelin recoveri inform analyt measur analyt result correct recoveri european food safeti author scientif technic assist elabor qualiti criteria valid method identif characteris primari smoke product laid regul qualiti criteria adapt account advanc scientif technolog knowledg measur provid regul accord opinion stand committe food chain anim health adopt regul articl qualiti criteria valid analyt method sampl identif characteris primari smoke product refer point annex ii regul ec set annex regul articl regul enter forc twentieth dai public offici journal european union regul bind entireti directli applic member state brussel april commiss marko kyprian member commiss oj oj scf cs cntm pah final decemb eu report la na en isbn iso accuraci trueness precis measur method result part gener principl definit geneva thompson ellison wood harmon guidelin singl laboratori valid method analysi pure appli chemistri pp horwitz protocol design conduct interpret method perform studi pure appli chemistri pp http www irmm jrc html activ intens sweeten smoke flavour liquid smoke compon xlsfaix al holz al roh amp werkstoff pp faix al holz al roh amp werkstoff pp faix meier fortmann holz al roh amp werkstoff pp faix meier fortmann holz al roh amp werkstoff pp oj decis amend decis ec oj annex qualiti criteria valid analyt method sampl identif characteris primari smoke product sampl basic requir obtain repres homogen laboratori sampl analyst ensur sampl contamin sampl prepar contain rins high puriti aceton hexan hlpc grade equival minimis risk contamin apparatu come contact sampl made inert materi glass polish stainless steel plastic polypropylen avoid analyt adsorb materi sampl materi receiv laboratori prepar test materi fine homogenis sampl give reproduc result satisfactori specif sampl prepar procedur identif characteris definit purpos annex definit appli solvent free mass mass materi abstract solvent water volatil fraction part solvent free mass volatil analys ga chromatographi identif primari product result descript analysi identifi substanc present primari product characteris primari product identif major physic chemic fraction quantif identif chemic constitu loq limit quantif lod limit detect si singl laboratori standard deviat calcul result gener repeat condit defin iso standard repeat standard deviat estim singl laboratori approach harmon guidelin singl laboratori valid method analysi sr averag laboratori standard deviat calcul result gener repeat condit defin iso standard collabor trial minimum laboratori conduct protocol design conduct interpret method perform studi sr laboratori standard deviat calcul result reproduc condit defin iso standard protocol design conduct interpret method perform studi rsdi rel singl laboratori repeat standard deviat si express percent measur rsdr rel averag repeat standard deviat sr express percent measur rsdr rel reproduc standard deviat sr express percent measur requir prejudic articl regul ec valid method identif characteris select laboratori compli qualiti criteria tabl tabl qualiti criteria method identif quantif chemic constitu solvent free mass volatil fraction primari product paramet comment solvent free mass mass identifi quantifi volatil fraction mass identifi quantifi tabl minimum method qualiti criteria analys polycycl aromat hydrocarbon pah analyt pah rsdi rsdr rsdr lod loq analyt rang recoveri μg kg μg kg μg kg benzo pyren benzo anthracen cyclopenta cd pyren dibenzo pyren dibenzo pyren dibenzo pyren chrysen methylchrysen benzo fluoranthen benzo fluoranthen benzo fluoranthen indeno cd pyren dibenzo anthracen benzo ghi perylen dibenzo pyren iso accuraci trueness precis measur method result part gener principl definit geneva thompson ellison wood harmon guidelin singl laboratori valid method analysi pure appli chemistri pp horwitz protocol design conduct interpret method perform studi pure appli chemistri pp analyt rang rsdi rsdr rsdr valu high due low stabil analyt primari smoke condens correct recoveri