commiss direct ec juli amend council direct eec includ trifloxystrobin carfentrazon ethyl mesotrion fenamidon isoxaflutol activ substanc text eea relev commiss european commun regard treati establish european commun regard council direct eec juli place plant protect product market amend commiss direct ec articl thereof accord articl direct eec unit kingdom receiv januari applic novarti crop protect uk inclus activ substanc trifloxystrobin annex direct eec substanc subsequ transfer bayer cropscienc act applic commiss decis ec confirm dossier quot complet quot sens consid satisfi principl data inform requir annex ii iii direct eec franc receiv applic articl direct eec februari fmc europ nv fmc chemic sprl carfentrazon ethyl applic declar complet commiss decis ec unit kingdom receiv applic articl direct eec april zeneca agrochem uk syngenta mesotrion applic declar complet commiss decis ec franc receiv applic articl direct eec septemb rhone poulenc agri sa bayer cropscienc fenamidon applic declar complet commiss decis ec netherland receiv applic articl direct eec march rhône poulenc agro bayer cropscienc isoxaflutol applic declar complet commiss decis ec activ substanc effect human health environ assess accord provis articl direct eec propos applic nomin rapporteur member state submit draft assess report substanc commiss april trifloxystrobin carfentrazon ethyl decemb mesotrion fenamidon februari isoxaflutol draft assess report review member state commiss stand committe food chain anim health review finalis april format commiss review report mesotrion trifloxystrobin carfentrazon ethyl fenamidon isoxaflutol review trifloxystrobin fenamidon reveal open question concern requir consult scientif committe plant carfentrazon ethyl review inform submit scientif committe plant separ consult committe ask comment relev human elev level specif porphyrin detect test anim committe express opinion effect substanc detect test anim porphyrin level relev human evid human sensit effect anim addit scientif committe note unknown polar compound detect lysimet notifi request comment relev compound addit inform subsequ provid notifi evalu committe assess data committe conclud polar compound unaccept ecotoxicolog toxicolog risk mesotrion scientif committe ask comment suitabl rat anim model extrapol toxicolog properti mesotrion human invit assess onset advers effect target organ anim model human link threshold concentr tyrosin plasma opinion committe conclud due similar tyrosin kinet mice human mous consid anim model rat human risk assess purpos committe conclud sign symptom advers effect expect human plasma tyrosin level nmol ml isoxaflutol scientif committe ask comment toxicolog ecotoxicolog effect degrad product activ substanc rpa statist analys tumour incid year rat studi observ development effect laboratori anim opinion committe note degrad product rpa worst case condit leach groundwat expect concentr exceed ppb committe identifi toxicolog ecotoxiclog concern regard degrad product committe identifi concern human relat carcinogen development effect consult substanc scientif committe ask comment degrad kinet assum model calcul leach behaviour committe found paramet model insuffici justifi half life time degrad rpa metabolit estim model calcul leach behaviour isoxaflutol degrad product subsequ revis line suggest scientif committe appear examin made plant protect product activ substanc concern expect satisfi gener requir laid articl articl direct eec regard examin detail commiss review report includ mesotrion trifloxystrobin carfentrazon ethyl fenamidon isoxaflutol annex order ensur member state authoris plant protect product activ substanc grant accord provis direct inclus member state allow reason period implement provis direct eec plant protect product trifloxystrobin carfentrazon ethyl mesotrion fenamidon isoxaflutol review exist provision authoris end period latest transform authoris full authoris amend withdraw accord provis direct eec amend direct eec measur provid direct accord opinion stand committe food chain anim health adopt direct articl annex direct eec amend set annex direct articl member state adopt publish march latest law regul administr provis compli direct forthwith inform commiss thereof appli provis april member state adopt provis refer direct accompani refer occas offici public member state determin refer made articl member state review authoris plant protect product trifloxystrobin carfentrazon ethyl mesotrion fenamidon isoxaflutol ensur condit relat activ substanc set annex direct eec compli amend withdraw authoris accord direct eec march latest authoris plant protect product trifloxystrobin carfentrazon ethyl mesotrion fenamidon isoxaflutol activ substanc activ substanc list annex direct eec septemb latest member state evalu product accord uniform principl provid annex vi direct eec basi dossier satisfi requir annex iii thereto basi evalu determin product satisfi condit set articl direct eec march latest amend withdraw authoris plant protect product articl direct enter forc octob articl direct address member state brussel juli commiss david byrn member commiss oj oj oj oj oj oj oj opinion scientif committe plant evalu carfentrazon ethyl context direct eec place plant protect product market scp carfen final adopt januari opinion scientif committe plant evalu mesotrion context direct eec place plant protect product market scp mesotri final juli opinion scientif committe plant inclus isoxaflutol annex direct eec place plant protect product market scp isoxa final june opinion scientif committe plant addit question commiss evalu isoxaflutol context direct eec scp isoxaflutol bi final januari annex annex row ad end tabl quot gt tabl gt quot