commiss decis juli proceed pursuant council regul eec case iv ciba geigi sandoz german text authent text eea relev ec commiss european commun regard treati establish european commun regard council regul eec decemb control concentr undertak hereinaft refer merger regul articl thereof regard eea agreement articl thereof regard commiss decis initi proceed case regard opinion advisori committe concentr notif consider made march concern propos merger ciba geigi ag ciba sandoz ag sandoz basl form singl enterpris novarti ag novarti decis april commiss order suspens notifi merger pursuant articl merger regul final decis examin notif commiss found project fell scope merger regul rais doubt compat common market decis commiss initi proceed pursuant articl merger regul advisori committe discuss draft decis juli parti ciba manufactur biolog chemic product health agricultur industri sector sandoz manufactur biolog chemic product health food agricultur build chemic sector ii concentr parti propos concentr merger mean articl merger regul ciba sandoz merg singl undertak novarti exchang share place sandoz sharehold receiv share novarti ciba sharehold parti intend concentr includ sector ciba special chemic busi industri chemic consist textil dye chemic addit pigment polym divis merger singl undertak accommod separ compani control compani quot stock exchang transfer novarti sharehold transfer inform provid parti group link novarti control compani inform provid parti ciba divis mettler toledo sold american investor group aea mt april contract sale implement offici approv sandoz build environ divis build chemic compris mbt hold ag sold merger sector regard part undertak concern mean articl initi brought novarti iii commun dimens combin aggreg worldwid turnov ciba sandoz ecu billion aggreg worldwid turnov ciba ecu billion sandoz ecu billion undertak aggreg commun wide turnov ecu million aggreg commun wide turnov ciba ecu billion sandoz ecu billion ciba sandoz achiev third aggreg commun wide turnov member state iv apprais articl merger regul ciba sandoz partli overlap busi activ health care product crop protect product anim health product seed inform provid parti overlap industri chemic nutrit build chemic weigh equip sector parti share number market exist market posit strengthen merger lack overlap health care product inform provid parti term health care product compris pharmaceut product contact lens len care product overlap activ ciba sandoz case pharmaceut product inform provid parti ciba market share case contact lens len care product eea wide basi nation level ciba achiev market share member state case contact lens member state case len care product view lack market share addit absenc indic merger strengthen ciba market posit evid suggest merger lead creation reinforc domin market posit propos merger lead market share addit larg number market pharmaceut product close apprais made effect case rauwolfia beta blocker calcitonin muscl relax aspect hs tk gene therapi merger lead creation reinforc domin market posit definit product market commiss occas dealt definit relev market case pharmaceut product establish number principl previou decis decis june sanofi sterl drug april procordia herbamond april rhône poulenc cooper june la roch syntex septemb ahp cyanamid februari glaxo wellcom april behringwerk ag armour pharmaceut june hoechst marion merrel dow septemb upjohn pharmacia medicin medicin subdivid therapeut class refer anatom therapeut classif atc recogn world health organ classif commiss earlier case medicin group refer composit therapeut properti level atc classif medicin group term therapeut indic intend oper market definit carri analys level atc classif combin group case product atc class substitut treatment specif ill diseas hand appli narrow market definit medicin question differ indic account fact medicin vari nation medicin subdivid segment basi varieti criteria demand relat criteria distinct medicin issu prescript sold counter distinct medicin cost refund part sick insur scheme cost reimburs segment partli overlap medicin issu prescript reimburs sold counter reimburs alloc medicin segment perman base decis author lead segment parti agre commiss case base market definit level atc classif level product gener serv treatment purpos interchang product class parti argu definit meet function substitut viewpoint side market view parti except aris atc class distinguish therapeut applic area pharmacolog activ principl applic formula market definit narrow case wide view confirm principl parti competitor consult commiss view definit product market base level atc classif individu case narrow wide interchang product depend principl physic technic chemic properti function substitut view supervis consumpt case medicin prescript establish medic practition prescript practic medic practition regularli influenc object scientif knowledg activ properti similar medicin bundesgerichtshof wuw bgh seq valium factor milit reach market definit includ degre toler medicin patient differ price case medicin prescript market definit base simpli medicin prescrib ill indic group criterion prescript base fundament medic ground prescript practic account medicin correspond term activ principl toler toxic side effect inform data exist atc classif parti market breakdown present data made refer classif drawn european pharmaceut manufactur associ ephmra underli im figur parti larg atc classif commiss investig shown parti competitor larg ident reason practic commiss breakdown nomenclatur emploi parti regard product market relev apprais merger parti view definit base level atc classif narrow medicin treatment high blood pressur rauwolfia beta blocker osteoporosi calcitonin term main indic interchang interchang product atc class case muscl relax contrast wide opinion parti market definit base level atc classif larg medicin relev apprais merger commiss investig contradict rauwolfia beta blocker rauwolfia medicin reduc blood pressur inform provid parti rauwolfia comb diuret medicin typic made reserpin diuret reserpin plant deriv activ substanc disadvantag induc depress lengthi period case diuret side effect lack potassium larg dose lengthi period combin number activ substanc attempt reduc side effect inform provid parti rauwolfia prepar oldest blood pressur medicin market parti substanc class treatment high blood pressur consist order market entri diuret central activ anti hypertens beta blocker vasodil blood vessel dilat agent calcium antagonist ac inhibitor parti eea member state medicin prescript treatment chosen serious high blood pressur accompani complaint previou treatment therapeut experi medic practition case question number wai achiev treatment aim number parti competitor cite prepar level atc class treatment high blood pressur except basic suitabl level atc classif market definit inform provid parti rauwolfia fastest sell blood pressur medicin ten fifteen year ago number countri includ germani austria itali parti rauwolfia prepar medic outdat number year younger doctor longer medicin base treatment exclus high blood pressur treatment tabl commiss investig confirm rauwolfia longer design choic blood pressur treatment relev public inform provid parti rauwolfia prepar prescrib continu treatment elderli patient countri larg scale predominantli patient adjust medicin long time proport rauwolfia prepar treatment high blood pressur steadili contract extent substitut vari individu member state commiss investig justifi nation product market definit rauwolfia abovement increas substitut rauwolfia blood pressur medicin misgiv presumpt rauwolfia prepar combin high blood pressur treatment medicin mention form singl product market fact choic medicin depend thing ag patient side effect medicin treatment high blood pressur consider side effect rule mutual substitut patient germani deutsch liga zur behandlung de hohen blutdruck drawn tabl show specif treatment level high blood pressur prepar milit assumpt complet mutual interchang addit characterist featur rauwolfia product report parti product longer recommend choic medicin treatment high blood pressur limit interchang prepar beta blocker diuret fact demand rauwolfia prepar steadili diminish show hat prepar nowadai prescrib predominantli categori patient parti point rauwolfia nowadai prescrib predominantli elderli patient substitut rauwolfia blood pressur medicin relev market ultim rat broader rauwolfia consider combin beta blocker diuret singl market commiss investig medicin recogn choic mean treat high blood pressur view wai prepar work side effect combin highli question commiss investig betablock comb betablock plain combin market betablock comb combin beta blocker prepar predetermin manufactur form applic appar declin replac combin dosag pure beta blocker medicin prefer dosag made medicin stem improv dosag option physician charg advantag combin reportedli patient fewer tablet adher carefulli correct dosag combin pure beta blocker beta blocker combin prepar correspond rauwolfia comb diuret class atc classif divis pure beta blocker beta blocker combin market lead inappropri subdivis commerci connect product market purpos decis examin question interchang beta blocker blood pressur medicin calcitonin inform provid parti calcitonin hormon occur natur human bodi bone format balanc hormon bone resorpt ag balanc shift bone resorpt result osteoporosi calcitonin primarili treatment osteoporosi inform provid parti calcitonin author sweden netherland treatment paget diseas rare bone diseas parti argu prepar treatment osteoporosi substitut calcitonin rate argu appli calcitonin prepar product class bone calcium regul diphosphon inform provid parti obtain prescript addit argu german school fluorid miner supplement calcitonin limit extent substitut parti substitut miner prepar calcium prevent osteoporosi lastli view parti hormon prepar oestrogen comb offer moder substitut inform provid parti doctor point view clear cut distinct prevent treatment treat osteoporosi boundari fluid parti argu internation recogn uniform object criteria question medic begin cost consider experi train doctor differ nation school patient symptom kei paramet determin treatment chosen inform provid parti main type prepar put commiss investig shown rate calcitonin diphospon regard predominantli substitut group singl product market treatment prevent osteoporosi parti increas bone densiti intend side effect parti side effect calcitonin rare encount sensat warmth irrit nasal mucou membran nausea diphosphon parti lead heartburn stomach complaint direct recent diphospon toler parti studi carri obtain evid long term decreas risk bone fractur decreas risk recogn medium term parti argu substitut rate major patient parti submit public show similar diphosphon calcitonin result commiss investig support swedish competit author point commiss enquiri medic product agenc confirm diphosphon case substitut calcitonin point appli prepar refer parti true fact prepar activ principl argu substitut calcitonin diphosphon bone prepar form report differ structur calcitonin report parti addit analges effect aspect irrelev osteoporosi gener pain view lack proper knowledg osteoporosi activ principl present priori suitabl patient inform provid parti calcitonin present administ nasal inject diphosphon author osteoporosi administ oral parti point british firm announc successfulli test oral administr form appli author end year addit italian firm report successfulli develop calcitonin administ oral differ exist form applic regard relev patient receiv caltitonin concern oral administr diphosphon rate repres disadvantag patient respect affect substitut individu atc class differ form administr group product market differ gener adduc decis argument diphosphon includ singl market ciba diphosphon aredia brand cover limit rang applic author suitabl treatment osteoporosi solut infus inform provid parti modern diphosphon oral form diphosphon author treatment osteoporosi rate merger control purpos regard substitut calcitonin pursu separ price strategi vi vi minor purchas calcitonin interchang prepar competit room manoeuvr supplier calcitonin vi vi purchas limit supplier diphosphon treatment osteoporosi calcitonin replac diphosphon case paget diseas muscl relax muscl relax includ level atc compris parti opinion indic distinguish fourth level distinct interchang pharmaceut class muscl relax parti member state eea prescript parti relev prepar ciba liores sandoz sirdalud area overlap insignific extent differ indic justifi assumpt separ market parti distinct made sever muscl spasm case multipl sclerosi harmless muscl spasm caus strain result lumbago similar spasm condit liores report exclus area sirdalud exclus ciba prepar author spastic case diseas central nervou system sandoz prepar spastic diseas central nervou system muscl spasm market sandoz product parti orient muscl spasm parti prescript panel europ show averag indic liores spastic diseas central nervou system spastic diseas central nervou system muscl spasm sirdalud muscl spasm spastic diseas central nervou system includ larg number indic central nervou system spasm area parti account illeg data data reason properli classifi higher proport case liores inform provid parti due fact rare diseas syndrom differ name spastic head spastic diseas central nervou system breakdown muscl relax relev product market parti substitut case indic tranquil case spastic analges cerebro peripher vasodil antiepilept urulog case harmless spasm analges antirheumat purpos decis decid market definit conclus clear level atc classif muscl relax broken separ product market compris medic product treatment spastic diseas central nervou system medicin product treatment simpl muscl spasm substitut individu product atc class activ substanc manufactur pharmaceut product gener take place separ process manufactur activ substanc manufactur pharmaceut manufactur pharmaceut mean mix activ substanc substanc manufactur galen form capsul tablet activ substanc manufactur hous purpos trade separ market activ substanc upstream market pharmaceut futur market pharmaceut industri full assess competit situat requir examin product market advanc stage develop extrem larg sum monei invest potenti product enter competit product develop stage market assess refer characterist intend therapeut born mind research develop rule trade pharmaceut compani intend primarili develop compani activ substanc product hand cooper take place research field pharmaceut compani public privat research institut small biotechnolog undertak relev resourc facil clinic test carri prior market author manufactur pharmaceut commiss amp potenti term import exist market futur market parti competitor survei commiss point trend commiss firm carri research develop research develop separ market evid base essenti fact research develop pharmaceut undertak engag research carri predominantli hous purpos research develop assess term import futur market relev product market natur defin clear cut manner case exist market market definit base exist atc class exist product replac guid primarili indic futur product appli fundament mode action account merger question call closer examin parti research activ field hs tk gene therapi treatment brain tumour tumour hs tk gene therapi parti involv heal genet condit diseas method appli therapeut substanc place hs tk gene therapi parti process suicid gene therapi enzym gene fed vector system diseas cell prodrug administ activ enzym gene prodrug mean drug pre stage conjunct enzym gene effect kill cell diseas cell kill healthi cell parti claim affect parti argu hs tk gene therapi direct competit gene therapi process chemotherapi immunotherapi radiat parti agre therapi pursu treatment tumour differ mode action hs tk gene therapi case market definit medicin product refer made sole common treatment object account activ principl lead degre effect toler market definit medicin product hs tk gene therapi treatment brain tumour tumour regard separ futur product market purpos decis final decis inclus therapi research work carri american subsidiari sandoz gti hs tk gene therapi area amp phase ii iii mean gti achiev substanti progress area market entri year parti point gti advanc uncertain form therapi market interest area note commiss mean area busi relev commiss establish larg amount financi expenditur incur market give consider market hs tk gene therapi geograph market manufactur medicin product market pharmaceut product defin nation market decis hitherto adopt commiss inquiri procedur shown reason depart decis make practic result commiss investig competitor parti bear effort european standard harmon technic provis commun entri forc registr procedur medicin repres complet programm common market term scientif technic requir appli medicin begin pharmaceut compani option case biotechnolog product oblig submit applic registr medicin european agenc evalu medicin product issu recommend commiss decis bind member state present medicin regist member state indic sale medicin influenc administr procedur purchas polici nation health author introduc member state countri exercis direct indirect influenc price level reimburs social secur system categori medicin reason price medicin product differ member state addit reach differ term brand pack size strategi distribut system differ market nation charact manufactur activ substanc market activ substanc situat upstream pharmaceut market contrast intern market examin commun level view lack custom barrier frequent mutual recognit product licenc unit state european econom area consider wider market definit parti competitor question commiss inclin assumpt worldwid market futur market extent futur product market consid basi research develop area nation restrict impact characterist futur market product regist research develop global consider futur market focu territori commun possibl worldwid market view part confirm competitor question refer made fact depend relev project market definit differ individu case geograph coverag patent relev geograph definit futur market case hs tk gene therapi patent separ appli grant unit state europ patent situat consider influenc market opportun competitor patent holder patent differ futur lend competit situat insid commun rate purpos decis assum commun relev geograph market competit assess set novarti creat largest supplier pharmaceut product world glaxo wellcom number larg supplier hoechst marion roussel merck amp bristol myer squibb american home product johnson amp johnson pfizer rhône poulenc rorer smith kline beecham share novarti worldwid sale pharmaceut product ciba sandoz involv research develop product activ chemic substanc product market pharmaceut product inform provid parti novarti activ medicin field immunolog inflamm diseas central nervou system cardiovascular diseas hormon metabol diseas cancer dermatolog asthma medicin product gener market condit drug manufactur distribut product possibl nation distribut compani wholesal turn sell pharmaci clinic larg custom manufactur nation distribut compani sell direct larg custom distribut system differ member state pharmaceut wholesal major purchas gener distribut pharmaceut product suppli countri concern carri comprehens stock influenc select quantiti pharmaceut product purchas gener simpli pass decis doctor pharmacist price medicin product regul directli indirectli nation law differ system reimburs price cost lead wide differ price medicin product member state gener characterist market pharmaceut product product introduc market complet develop test undergo consider time differ product product phase expans depend patent situat competitor enter market depend product success market addit competitor enter market patent protect end suppli medicin product form gener product statement made pharmaceut compani question main barrier market entri length time need research develop heavi expenditur involv market product partli result nation registr futur market entri compani product undergo research develop parti draw distinct phase develop phase mark start clinic test human year product market project phase claim chanc success rule phase activ public undertak concern phase ii year product market involv work proper dose patient defin area applic success rate phase iii start year product market involv establish product effect larger group patient phase iii risk failur amount clinic test complet registr phase rule take year registr obtain take month depend member state price establish approv cost reimburs social secur work product final market patent protect expir market entri parti state costli competitor activ pharmaceut manufactur long activ substanc medicin product cover patent protect market entri cost inform provid parti high competitor acquir licenc invent activ ingredi work similar infring origin patent parallel product entir preclin clinic develop process parti year cost ecu million parti group medicin product regist indic gener assum indic type advertis sale promot unregist indic prohibit doctor prescrib unregist indic incur specif liabil risk regard cost reimburs system differ countri countri parti state case cost reimburs medicin product indic area regist condit doctor specif justif parti argu medicin product indic regist quantit signific special featur product medicin affect signific market share apprais market situat rate gener product compet affect market competitor activ market origin prepar competit provid product remain enter market weight pharmaceut industri industri easier manufactur extend capac restrict competit scope lead supplier deriv market share greater extent market competitor extend capac util substanti resourc frequent consider delai competit scope aris delai larg disappear case supplier medicin supplier present market gener extend capac quickli product capac case medicin protect patent contract product parti inform provid parti capac util manufactur activ substanc pharmaceut prepar estim industri wide case prepar protect patent product contract give rise problem protect busi secret mechan fulli oper effect merger parti activ varieti pharmaceut product market achiev substanti market share larg number nation market product market broken accord level world health organ atc classif propos merger lead addit market share nation market parti strong posit market notif parti nation market affect market mean implement regul involv total product group antinaus nitrit rauwolfia amp comb amp diuret variocos therapi syst betablock plain betablock comb topic antipurit estrogen estrogen amp progesteron comb calcitonin la immunosuppress agent antirheumat nonsteroid muscl relax central antimigrain antismok product throat prep ophthalmolog potassium miner supplement corticosteroid comb syst nasal prepar steroid resp antituss parti combin market share affect market small patent protect medicin manufactur expir gener product exist market entri gener product place primarili larger market due fact gener product produc market entri cost deriv nation requir registr medicin repres substanti barrier market entri market turnov small expiri patent protect necessarili entail chang suppli market cost involv obtain nation registr compris registr cost cost prepar dossier dossier produc registr member state part applic member state nation market involv product parti achiev market share parti activ individu product market eea lead combin market share nation market sign respect parti potenti competit relationship market gener small parti activ commun tend insignific discern incent parti enter market nation product market involv product case parti achiev sale eea parti market share market propos concentr expect creat strengthen domin posit activ overlap concentr lead reduct actual competit parti supplier pharmaceut product regard potenti competitor principl hold good larg supplier pharmaceut product reason relev restrict potenti competit result product elig market definit level atc classif broader market definit rise addit overlap parti activ larger market share market market share addit parti research develop project phase ii iii give rise overlap market parti strong market posit evalu effect concentr product market number gener market condit basic account price regul nation author restrict supplier scope competit behaviour gener pressur exist reduc health care cost increas price pressur supplier supplier pharmaceut product present market gener find simpler extend capac supplier number econom area experienc equival success market greater flexibl competitor react reduc signific high market share rauwolfia amp comb diuret take area blood pressur product parti share small inform provid competitor parti achiev correspondingli broadli defin market commun wide share tend fall slightli posit parti put perspect outset market share achiev individu product market parti scope competit behaviour typic compani domin posit case rauwolfia concentr competit supplier rauwolfia prepar blood pressur product take sale rauwolfia parti achiev higher share rauwolfia supplier present affect market gt tabl gt gt tabl gt gt tabl gt gt tabl gt gt tabl gt born mind sale rauwolfia amp comb amp diuret fall sharpli parti sale absolut term fallen inform provid medicin longer protect patent basic patent activ substanc expir inform provid parti price germani ciba product rose sandoz product price increas bare gener rate inflat occur period gener regard sign scope domin behaviour true markedli smaller price increas sandoz sandoz largest supplier german market scope set price competitor final scope competit behaviour typic domin compani rule case rauwolfia consider pressur competit high blood pressur product betablock consider parti combin share fall germani itali austria spain eea propos concentr expect lead creation domin posit betablock case betablock comb parti product basic longer patent protect gener product market ciba patent specif fraction sustain releas tablet logroton patent expir year franc countri parti achiev high combin share betablock comb amount ciba sandoz combin total inform provid parti larg supplier product merck sharp dohm total turnov achiev product franc ecu million sale betablock comb shrink franc eea sale betablock plain case show mark rise parti combin market share franc market betablock includ betablock plain inform provid parti zeneca lead supplier betablock eea parti expect acquir domin posit result concentr calcitonin diphosphon parti rule high market share market calcitonin disphosphon treatment osteoporosi paget diseas competit strength product market base sole calcitonin activ involv disphosphon treatment paget diseas osteoporosi strength parti vari calcitonin sandoz supplier brought calcitonin market nasal sprai advantag inject led consider increas sandoz sale figur inform provid parti nasal sprai suppli itali rhône poulenc procter amp gambl gener manufactur registr nasal sprai expect countri hand ciba unsuccess develop nasal sprai inform provid parti fact human calcitonin ciba inject unsuit administr form nasal sprai oral prepar ciba meantim larg ceas effort compet calcitonin inform provid parti basic patent calcitonin expir eea countri ciba patent stabl solut human calcitonin patent protect decemb fibril human calcitonin patent protect april case miacalcin salmcalcitonin sandoz process protect austria patent nasal sprai formul miacalcin report parti success product parti product develop area market year develop sandoz calcitonin research phase iii inform provid parti brought market year time relat special form osteoporosi caus take cortison prepar long period exact sale figur exist calcitonin product group relev market inform market share base estim provid parti market structur propos concentr expect lead creation strengthen domin posit parti member state market calcitonin diphosphon regist treatment osteoporosi paget diseas belgium parti achiev combin market share sandoz ciba parti assum ciba forc belgian market year germani inform provid parti sandoz domin market posit germani number manufactur enter market time sale fallen consider intensifi competit market success entrant diphosphon includ parti market share basi estim fall sandoz ciba market share tend fall disphosphon introduc germani treatment osteoporosi inform provid parti boehring mannheim lead supplier diphosphon medac procter amp gambl gehe activ germani parti submit calcul share calcitonin germani basi pack unit show market success gener manufactur calcul show basi pack unit share sandoz prepar karil fell share cibalcalcin enter market rose fell inform provid parti ciba market success peak connect strong public devot human calcitonin comparison calci made hexal enter market share rose slightli lead prepar calcitonin made ratiopharm enter market reach ostostabil made jenapharm achiev share supplier includ rhône poulenc rorer azupharma toss durachemi pharmacia upjohn view parti fact long run calcitonin inject market prospect ascertain trend character market share rhône poulenc rorer calsynar inject peak reach franc franc parti combin market share fall sandoz expect bring nasal sprai french market assum time manufactur introduc nasal oral form prepar diphosphon interchang calcitonin treatment osteoporosi achiev larg market volum calcitonin basi parti estim disphosphon includ combin market share sandoz ciba greec portug calcitonin market greec portug grown consider recent year sandoz market share fallen markedli ciba market share fallen time competitor rhône poulenc rorer enter market achiev appreci market share basi estim submit parti disphosphon includ combin market share greec sandoz ciba disphosphon introduc greec market share expect fall substanti basi estim submit parti disphosphon includ combin market share portug sandoz ciba disphosphon introduc portug inform provid parti larg replac calcitonin treatment osteoporosi partli calcitonin restrict govern measur reason market contract itali itali itali largest market calcitonin market volum ecu million inform provid parti high expenditur calcitonin itali led situat health author wish limit prescript refus reimburs cost calcitonin market shrunk competit intensifi view parti ciba continu longer estim submit parti disphosphon includ parti combin market share sandoz ciba austria austria ciba market share fall sharpli compet product elcimen made nycom norwegian manufactur consider market posit estim submit parti disphosphon includ parti combin market share sandoz ciba sweden netherland sweden netherland calcitonin regist treatment osteoporosi paget diseas market volum small countri osteoporosi predominantli treat hormon prepar disphosphon calcitonin regist treatment osteoporosi market volum increas substanti provid incent supplier enter market commun swedish competit author disphosphon interchang calcitonin regist sweden supplier includ astra roch boehring mannheim patent expir sweden competitor activ member state enter market parti rais price muscl relax muscl relax parti combin market share insignific parti product basic found market take muscl relax concentr expect give rise creation strengthen domin posit rang compet prepar difficult calcul actual market share medicin fact partial replac prepar inform provid parti sever spastic occur symptom ill case harmless muscl tension combin market share appreci sandoz prepar regist indic admittedli inform prescript panel ciba prepar simpl muscl tension stand regist condit inevit simplif kind statist evalu insignific share sale ciba prepar regard compet product sandoz prepar area assum slight strengthen effect lead creation strengthen domin posit inform provid parti sandoz substanc protect sirdalud belgium procedur protect spain patent protect longer exist larg number gener compet product parti activ overlap significantli market medicin treatment spastic case diseas central nervou system product regist indic market sandoz product gear case simpl muscl tension sale prescript spastic indic total case sandoz product sandoz product regist indic parti activ overlap extent slight lead creation strengthen domin posit inform provid parti patent protect ciba prepar expir inform provid parti number gener exist liores expiri patent protect addit inform provid parti scope competit behaviour limit number product treatment sever spastic prepar benzodiazepin group activ substanc inform provid ciba sandoz activ market manufactur activ substanc margin manufactur activ substanc exclus purpos concentr expect lead creation strengthen domin posit futur market market strength undertak research develop difficult estim success amp assess amp complet undertak exist amp potenti competit assess futur competit strength base precis potenti parti strong biotechnolog genet engin field strength base primarili number cooper agreement stake undertak research establish hold cooper arrang parti access patent field call closer examin area genet engin research treatment brain tumour type tumour import connect sandoz stake gti ciba stake increas chiron gti research hs tk gene therapi phase ii iii patent ec appli inform provid parti viagen subsidiari chiron research work preclin stage phase certainti time requir achiev result area diseas treat rule hitherto adequ treat author develop process possibl quickli case tradit medicin product replac effect commiss establish curs investig parti result hold exclus access combin broadli defin patent cover retrovir hs tk herp simplex thymidin kinas construct retrovir vector method treatment brain tumour tumour retrovir vector sandoz strong posit area subsidiari gti endeavour develop gene therapi brain tumour unit state viagen patent applic relat area develop success gene therapi brain tumour patent applic cover wide spectrum patent claim patent issu coverag appli similar coverag combin result merger competitor larg exclud part field research gene therapi brain tumour tumour patent right pose consider entri barrier competitor futur market amp result market number patent held undertak account undertak find wai market amp result infring patent right acquir relev licenc patent exist area research wider coverag patent difficult situat individu case problem aris individu supplier combin patent make difficult imposs supplier gain market access infring patent merger lead hold combin patent market foreclosur result parti argu patent applic attribut chiron broadli formul highli improb grant detail specif argu patent attribut chiron cover treatment brain tumour tumour view relev patent grant propos merger lead combin patent result market foreclosur lastli parti object exclus access patent attribut chiron inform deriv market combin futur patent right gti viagen block develop gene therapi tumour treatment method undertak uncertain situat appli rate merger place competitor substanti wors negoti posit obtain licenc gti chiron merger worsen competitor negoti posit result market domin depend essenti condit gene therapi ultim prove success method treatment research result open wai circumv obstacl creat combin patent patent situat unclear parti submit patent applic patent grant condit realiti propos merger lead structur danger foreclosur futur market hs tk gene therapi tumour parti power competitor market access issu licenc condit appli examin futur market ultim amount market creat problem aris state gti research project phase ii iii predict method treat tumour appli view progress made research suffici probabl warrant protect market term competit condit difficult assess current term parti competitor futur prevent market product result patent view larg amount expenditur incur research find circumv difficulti obtain licenc inform found endeavour requir addit time monei possibl mean rule competitor seek find wai kei question creation competit problem parti obtain patent block effect appli primarili block effect patent applic attribut chiron creat competitor gti pursuit compet product commiss investig identifi substanti market fear respect grant patent depend precondit parti assert patent claim basi specif includ area hs tk gene therapi tumour precondit sole hand parti extent propos merger pose increas structur danger market foreclosur precondit actual grant patent hand parti patent applic exert disrupt effect undertak wish market hs tk gene therapi tumour bear mind patent broad specif possibl grant confront question carri invest area seek round patent view abstract term pose obstacl competitor wish gain market access suffici conclud parti domin posit market ultim suffici probabl merger futur market lead creation strengthen domin posit commiss note merger control proceed parti made statement undertak make bind statement behalf novarti ag novarti exercis potenti legal contractu influenc result hold chiron corpor emeryvil california unit state america board member appoint ensur chiron subsidiari viagen issu interest firm term condit customari trade industri exclus licenc european patent nation patent deriv therefrom base intern patent applic no wo wo hstk herp simplex thymidin kinas gene therapi tumour oblig subject proviso conduct novarti board member appoint accord law interest chiron sharehold oblig appli year issu european patent plant protect relev product market plant protect area distinct made herbicid weed control fungicid diseas control insecticid insect control seed treatment protect seed subsequ plant diseas insect trace element overcom defici symptom iron defici growth regul herbicid demand front type plant protect relev herbicid main factor determin substitut factor type weed activ ingredi time applic plant protect product influenc substitut herbicid herbicid treat weed affect type plant maiz cereal case herbicid protect plant substitut limit substitut herbicid protect cereal fruit sugar beet herbicid protect type plant constitut separ relev product market iv hoechst schere point seq iv american cyanamid shell point seq assess competit relationship born mind larg number herbicid wide spectrum activ breakdown herbicid term weed intend treat conceiv iv american cyanamid shell point specif type plant affect mix weed popul compris grass broadleav weed herbicid made entir popul weed treat make weed popul season variabl herbicid suitabl treat grass herbicid suit treat broadleav weed commiss investig farmer purchas seri herbicid specif select mix accord type weed purchas readi made product desir mixtur principl substitut product narrow spectrum activ broader spectrum addit divid line product group fluid make imposs draw hard fast classif breakdown base time herbicid appli disregard pre sow pre emerg post emerg herbicid treat type weed displai degre effect sow herbicid group farmer concern substitut fungicid fungicid prevent deterior plant plant product fungi mould prior harvest fungicid chemic composit fungi mould number type plant fungicid protect fruit cereal potato sugar beet purchas kei question determin product purchas harm organ relev fungicid treat type plant protect iv hoechst schere point seq fungicid rule combat individu harm organ combat prevent entir complex harm organ exampl includ typic cereal diseas rust powderi mildew eyespot septoria fusarium case sugar beet main type diseas occur powderi mildew rust cercospora ramularia combin potato hand affect exclus late blight plant displai differ albeit partli overlap diseas pattern breakdown fungicid type plant commiss view addit breakdown fungicid market potato fungicid subdivid contact product penetr product system product product combat diseas partli prevent partli cur vari durat effect case mix product mix grower order achiev optimum effect specif circumst breakdown product group case lead doubl tripl count breakdown type plant partial subdivis broad narrow select breakdown product broad spectrum narrow spectrum disregard case plant singl harm organ control late blight case potato plant entir complex harm organ occur fungicid predominantli broad spectrum broad spectrum simultan effect type harm organ rest comment made respect herbicid market appli similarli breakdown fungicid term differ stage develop plant case fungicid exist combat specif harm organ earli middl late develop stage cultiv plant effect develop stage comment treatment seed insecticid insecticid product control insect damag cultiv plant case fungicid insecticid control specif type insect irrespect type plant affect plant attack insect plant specif insect breakdown insecticid type plant assess competit relationship born mind larg number insecticid treat plant farmer grower gener purchas product combat group harm insect composit vari type plant purchas product broad spectrum activ combin product broad spectrum specif select insecticid narrow spectrum mix farmer point view insecticid broad spectrum combin insecticid narrow spectrum basic substitut addit breakdown market type plant breakdown insecticid spectrum addit breakdown term broad narrow spectrum reason seed treatment seed treatment plant protect product intend protect seed subsequ plant diseas insect treatment seed base predict diseas insect seed subsequ plant affect product fungicid insecticid seed basic plant specif composit slight substitut product treatment seed plant relev product market defin type plant parti argu notif treatment seed constitut separ product group plant protect area left open question involv separ market similarli public novarti background attach notif product group seed treatment identifi page separ fungicid insecticid submiss parti view seed treatment separ market essenti reason final purchas farmer purchas readi treat seed treat seed insecticid concern farmer treat seed appli granul insecticid seed row sow carri blanket row sprai liquid prepar addit prophylact procedur farmer possibl defer treatment sign infest occur chart attach submiss sow time applic durat effect durat applic effect profil seed treatment involv hand soil treatment granul blanket treatment soil liquid prepar prior sow overlap essenti appli case fungicid diseas occur bean pea damp seedl downi mildew ascochyta leaf blight botryti seedl diseas control seed treatment product protect seed seed protect product control seedl diseas downi mildew leaf blight downi mildew leaf blight control mean seed treatment sprai treatment botryti control mean sprai treatment product effect botryti leaf blight seed treatment type applic insecticid fungicid serv purpos product appli soil sprai seed treatment seed grain dress ciba sandoz dress seed grain suppli seed treatment product firm dress plant commiss view fact justif identifi separ market seed treatment market dress seed note treat seed form farmer point view ultim substitut fungicid insecticid appli soil sprai commiss conclud separ market seed treatment trace element trace element treat defici symptom iron defici breakdown type plant regard type plant suffer predominantli nutrient defici growth regul growth regul individu plant type form separ relev market market merger creat market share addit sandoz market produc growth regul activ substanc manufactur plant protect product take place stage manufactur activ substanc manufactur formul formul product activ substanc packag formul ciba sandoz manufactur activ substanc plant protect central factori manufactur formul packag contrast carri plant ciba sandoz competitor sell exchang activ substanc firm market activ plant protect substanc activ substanc uniqu properti patent registr author plant protect product inform activ substanc contain product manufactur activ substanc rise anther product similar effect product author sought commiss investig take month year author obtain addit manufactur formul product anew test product effect appli author time reason activ substanc basic substitut relev geograph market parti view relev market plant protect product commun wide market market definit support exist larg number major multin group central product plant low transport cost proport total cost case commun wide patent protect individu plant protect product addit market plant protect product commun harmon council direct eec hand plant protect product includ activ substanc formul regist member state market month year requir time applic author product depend member state product involv gener activ substanc formul price differ member state product substanti sign tendenc align price custom agricultur cooper wholesal purchas relev product nation level europ wide basi supplier case nation sale organ distribut product sale organ manufactur oper relev member state distribut market share member state differ wide similarli suggest nation differ competit relationship addit differ composit individu product method depend condit exist individu member state agricultur plant health environ climat soil properti topographi iv hoechst schere point seq iv american cyanamid shell point seq definit relev geograph market left open herbicid insecticid trace element market concern appli narrowest nation market definit market definit merger creat strengthen domin posit market activ substanc plant protect concern market assum commun wide custom part larg fairli larg undertak good overview market purchas product world wide basi addit transport cost insignific market access restrict result nation author requir market competit assess comment market activ substanc dealt competit relationship fungicid herbicid insecticid area similar combin head discuss trace element head activ substanc plant protect product individu case market activ substanc consist singl substanc activ substanc enjoi patent protect manufactur firm monopoli merger alter situat market commod protect activ substanc number supplier principl undertak relev technolog suppli activ substanc ciba oper market market activ substanc plant protect product merger creat strengthen domin posit manufactur plant protect product purchas activ substanc competitor formul product activ substanc purchas patent product purchas enter relationship depend patent holder manufactur activ substanc wide downstream product market enjoi potenti strong posit downstream market market share market small commiss investig parti bui sell activ substanc competitor rule competitor longer suppli futur novarti result strengthen posit downstream market conduct thought highli market particip survei competitor bui sell activ substanc relationship mutual depend fungicid herbicid insecticid commiss investig merger affect market list fungicid herbicid insecticid area commiss investig shown market share case differ substanti discuss market share vari year year case mean depend base year market extent affect merger appli case combin share market affect year base year refer year base year suffici accur pictur market affect merger market share calcul base rate larger member state concern call panel studi carri undertak case smaller member state calcul carri parti check commiss basi compar data provid competitor ciba sandoz manufactur sell fungicid herbicid case supplier plant protect product turn suppli product trade notif parti attribut sale sandoz ciba product relev supplier similarli sale plant protect product supplier ciba sandoz attribut ciba sandoz suppli custom type market share calcul line panel studi commiss view market share calcul carri parti panel studi correctli reflect actual market posit parti competitor appli member state sandoz ciba sale organ ciba sandoz case assum sole product merger carri novarti sandoz ciba establish sale organ market product supplier parti market share base product manufactur parti principl time threaten undertak actual market move sale product period notic twelv month agre sale contract parti market ciba sandoz product order supplement product rang ciba sandoz product extent sold part packag undertak product open question product sale ciba sandoz declin sale agreement parti termin assess parti market share instanc high matter reduct made parti combin market share merger creat strengthen domin posit merger parti broad product rang product direct competit assum merger product rang ration affect product ciba sandoz hitherto market parti order supplement product rang reason undertak principl termin sale agreement twelv month ground reduc parti market share volum parti achiev sale parti product market share calcul includ product sold competitor exclud product purchas competitor rate fungicid sector show addit affect market case calcul accord panel studi instanc signific differ market share potato fungicid franc parti combin market share reduc herbicid sector market share show signific differ case fruit nut franc similarli reduct affect market identifi case maiz herbicid inclus product market competitor market combin share maximum affect merger product market competitor includ affect market combin market share market affect merger fungicid herbicid insecticid sector fungicid fruit nut franc ciba sandoz portug ciba sandoz fungicid veget belgium ciba sandoz franc ciba sandoz itali ciba sandoz fungicid cereal belgium ciba sandoz germani ciba sandoz franc ciba sandoz great britain ciba sandoz netherland ciba sandoz austria ciba sandoz spain ciba sandoz fungicid potato belgium ciba sandoz germani ciba sandoz franc ciba sandoz great britain ciba sandoz itali ciba sandoz portug ciba sandoz spain ciba sandoz fungicid sugar beet belgium ciba sandoz franc ciba sandoz itali ciba sandoz austria ciba sandoz spain ciba sandoz fungicid bean pea cattl fodder franc ciba sandoz herbicid fruit nut franc ciba sandoz herbicid veget belgium ciba sandoz great britain ciba sandoz herbicid maiz belgium ciba sandoz franc ciba sandoz itali ciba sandoz austria ciba sandoz germani ciba sandoz netherland ciba sandoz portug ciba sandoz great britain ciba sandoz insecticid fruit nut franc ciba sandoz insecticid veget itali ciba sandoz insecticid bean pea cattl fodder franc ciba sandoz comment concern market parti achiev joint market share appli mutati mutandi condit competit market affect market volum market share competitor fungicid eea wide volum term market cereal fungicid ecu million neg growth rate largest market franc ecu million germani ecu million great britain ecu million compar volum term found market cereal herbicid market cereal fungicid franc ciba gain addit market share lost compar sandoz lost roughli held market share compar competitor basf market share bayer agrevo subsidiari hoechst schere du pont zeneca rhône poulenc american cyanamid small market share franc larger member state similar set characterist market share fluctuat significantli time strong competitor observ market cereal fungicid germani belgium netherland spain great britain austria eea wide volum term market potato fungicid ecu million largest market netherland ecu million germani ecu million franc ecu million great britain ecu million belgium ecu million market potato fungicid franc parti combin market share easili largest competitor period sandoz gain addit market share lost ciba lost gain lost parti bayer du pont agrevo jsb market entri elf aquitain market entri sostra present market small market share rohm haa pictur parti market leader present portug spain potato fungicid market concern fluctuat market share multitud strong competitor put high market share parti potato fungicid market perspect addit parti margin manoeuvr restrict factor discuss detail possibl competitor increas output frequent product launch possibl market entri price competit gener product countervail power custom eea wide volum term market sugarbeet fungicid ecu million largest market itali ecu million franc ecu million greec ecu million market sugarbeet fungicid franc parti clear leader combin share ciba ad remain level sandoz held market share compar parti zeneca du pont elf aquitain agrevo sostra small market share larg fluctuat market share multitud competitor likewis observ austria belgium itali spain austria belgium spain sandoz enter market quickli captur larg market share similarli du pont enter spanish belgian market case compani left market agrevo american cyanamid belgium case potato fungicid sugarbeet fungicid parti strong market posit franc promin market share histor reason sandoz strength french market world war franc sandoz agri divis resum activ time varieti manufactur product sold sale organ built serv market sandoz product mention discuss potato fungicid market parti margin manoeuvr restrict high market share volum term market fungicid bean pea cattl feed franc ecu million sandoz increas share market won addit ciba gain lost largest competitor zeneca market share parti sostra basf sumitomo rhône poulenc smaller market share herbicid volum term market fruit nut herbicid franc ecu million market ciba gain period lost sandoz share increas slightli largest competitor monsanto lost market share gain share competitor zeneca elf aquitain dow elanco sostra agrevo volum term market veget herbicid great britain ecu million roughli unchang market ciba gain market share period lost sandoz enter market straightawai achiev share nearest competitor basf american cyanamid zeneca monsanto agrevo eea wide volum term market maiz herbicid ecu million compris growth growth record largest market franc ecu million germani ecu million itali ecu million market maiz herbicid germani parti clear leader combin market share ciba lost win back sandoz gain largest competitor du pont roughli rhône poulenc loss market share gain american cyanamid spiess urania basf greater market share fluctuat occur belgian market maiz herbicid ciba lost sandoz gain market share gainer includ zeneca loser basf protex rhône poulenc broadli maintain market share anim market austria franc itali netherland portug great britain market maiz herbicid monsanto repres market share case sandoz increas market share maiz herbicid market larg due acquisit end pyrid activ substanc maiz herbicid busi agrolinz austria sandoz sell direct germani belgium competitor maiz herbicid product activ substanc origin belong agrolinz case larg market share parti maiz herbicid market synonym correspondingli larg margin manoeuvr margin manoeuvr restrict number strong competitor factor discuss detail possibl competitor increas output frequent product launch possibl market entri price competit gener product countervail power custom insecticid except market insecticid bean pea cattl feed franc combin market share parti insecticid sphere volum market insecticid bean pea cattl feed signific franc amount ecu million market share fluctuat sharpli time parti competitor zeneca market share american cyanamid bayer agrevo rhône poulenc product capac fungicid herbicid insecticid basic manufactur factori multipurpos plant capac util product plant averag reason competitor rapidli increas output time product launch market entri potenti competit observ market structur show market share fluctuat sharpli time due frequenc product launch inform obtain commiss competitor nation registr author show market concern high rate product launch continu expect parti mention seri entrant market fungicid herbicid insecticid larg japanes undertak sumitomo nissan isk supplier iv american cyanamid point sumitomo nissan enter market acquir rhône poulenc subsidiari rhodiagri direct entri complet competitor unknown set sale network task carri agricultur cooper wholesal sale promot advertis cost absorb distributor expenditur met margin similarli gener manufactur griffin corp usa sanachem usa unit phosphoru india recent enter european market market share small market entri cost gener manufactur estim ecu million toxicolog doubt product occur product ecu million improv product formula activ substanc reach market quick success competit pressur gener consid small market particip gener manufactur establish gener gener manufactur disciplin effect supplier origin prepar product market exhibit higher state art gener observ sharpli fluctuat market share made clear manufactur fungicid herbicid insecticid hitherto activ member state enter market member state exampl dow elanco american cyanamid zeneca potenti competitor sens monsanto rohm haa fmc market entri japanes undertak mitsubishi mitsui increas competit gener manufactur eastern europ south east asia expect market particip market entri field fungicid easier competitor hitherto activ field herbicid complet newcom synergi sale market scarc exist import sphere amp good knowledg maiz herbicid facilit entri market cereal herbicid amp perspect sens bayer agrevo refer enter market market field herbicid fungicid insecticid concentr admittedli lead addit market share undertak involv market share case individu case market share explain undertak hitherto activ market member state occasion enter market member state result concentr potenti competitor disappear market undertak involv activ potenti competitor sandoz competitor activ market swedish market cereal fungicid ciba share agrevo zeneca rhône poulenc dow elanco addit observ market share fluctuat ciba won market share sweden larg number strong competitor sweden basf bayer du pont market entri exit frequent introduct product appli market demand condit dealer agricultur cooper essenti carri complet rang product final custom farmer frequent carri applic order instanc treat diseas spectrum develop stage plant farmer requir formula mix manufactur absolut suppli complet product rang appli iv hoechst schere point opinion market particip broad product rang competit advantag supplier cooper view offer complementari product jointli market parti advantag respect combin crop protect seed treatment product part larg distribut channel agricultur cooper case meet crop protect demand region enjoi concentr buyer power ciba sandoz manufactur complementari product area suppli complet rang product concentr parti posit threaten set sale organ possibl escap disciplin effect agricultur cooper partial concentr buyer power commiss investig develop admittedli probabl alongsid deal advisori function essenti deal neutral individu manufactur develop relationship trust farmer extent set sale organ field servic logist wareh distribut costli involv consider financi risk brand loyalti secondari import crop protect product select criterion product effect control weed insect harm organ effect product market chang quickli occur market share fluctuat confirm point potenti buyer novarti prevent creat domin posit presenc strong competitor market concern novarti rais price consider market potenti buyer threaten futur purchas product herbicid fungicid insecticid market novarti competitor parti margin manoeuvr price influenc competit relat crop protect market indirectli competit relat crop protect market research develop supplier crop protect product activ sector fungicid herbicid insecticid correspondingli larg amp potenti amp intens suitabl quick success product market supersed predecessor strong market posit todai guarante strong posit futur iv american cyanamid shell point novarti turnov crop protect product worldwid roughli europ roughli half time nearest competitor agrevo du pont monsanto zeneca bayer rhône poulenc dow elanco american cyanamid worldwid turnov ecu billion ecu billion crop protect sector novarti amp capac correspondingli larg number research success high account synergi amp ciba sandoz achiev result concentr novarti succe keep research expenditur lower rel term competitor amp intens date maintain economi scale lead addit strengthen novarti amp potenti supplier crop protect product unanim think larg capac guarante success amp project assum current trend novarti maintain possibl extend posit market leader crop protect sector commiss investig reveal parti aforement competitor critic size effect amp activ competitor parti succe pool activ substanc market cereal fungicid obtain synergi quickli bring effici product market cooper place amp sector regard develop activ substanc effect commiss opinion achiev todai extent addit strengthen parti posit sector result concentr small crop protect product partli supersed distant futur suitabl genet modifi seed genet engin modif result plant protect harm organ insect observ part seed strong market posit ciba crop protect sandoz seed treatment lead synergi stronger market posit parti knowledg fungicid insecticid effect microorgan gene trigger effect biotechnolog method introduc gene appli seed crop protect inform market particip competit advantag result simultan activ seed crop protect fungicid insecticid conflict interest aris crop protect seed treatment divis product pursu goal mean herbicid sector product complementari competit relationship elimin weed unlik action fungicid insecticid replac biotechnolog treatment herbicid serv elimin weed cultiv plant damag plant remov weed broad spectrum herbicid undertak activ sector addit parti monsanto agrevo biotechnolog make cultiv plant toler herbicid ciba sandoz devot limit amount amp area ciba sandoz hold patent crop protect sector expir year competit situat detail show patent right market creat domin posit potenti buyer genet product fall back older product patent protect expir supplier product gener demand excess high price conclus parti high market share case market leader market time remain account strong posit amp sphere signific market share fluctuat time larg number competitor market concern likewis signific amp capac competitor larg number product launch complet expect futur entri exit market concern price disciplin effect gener product countervail power wholesal agricultur cooper show concentr creat strengthen domin posit result effect competit significantli imped common market substanti part trace element parti market trace element sector affect concentr trace element fruit nut spain ciba sandoz trace element veget spain ciba sandoz market concern parti market leader market trace element fruit nut agrevo market share sostra rhône poulenc bayer market trace element veget nearest competitor rhône poulenc agrevo remaind market share case larg number competitor local firm suppli product remedi iron defici veget fruit nut market concern trace element sector market share fluctuat time sharpli fungicid herbicid insecticid sector ciba activ market trace element fruit nut franc greec itali clear market leader countri market share itali ciba face competit american cyanamid du pont zeneca rhône poulenc valagro zeneca du pont activ itali enter nation market greec hellapharm rhône poulenc supplier alongsid ciba franc remaind market share competitor local undertak firm de rour bardentan market share firm involv patent product trace element sector sandoz sell product field uncertain overlap market question left open concentr creat strengthen domin posit market larg market share parti presenc potenti strong competitor multitud smaller competitor fluctuat market share time situat patent commiss find domin posit creat strengthen market trace element result concentr anim health product anim health product small anim ectoparasiticid relev product market anim health product type vaccin food addit veterinari medicin hygien product subdivid determin relev product market present case subdivis vaccin addit parti activ market market affect purpos form veterinari medicin sector subdivid anti microbi drug antibiot appli form inject ointment drop parasiticid prevent parasit product group product affect merger anti microbi drug regard anti microbi market treatment swine dysenteri affect parti opinion market veterinari medicin administ diseas break prevent primari goal prevent diseas prepar swine dysenteri parti argu situat effect pig poultri diseas respiratori digest tract commiss disput fact inclin view custom pig farmer standpoint make bui product work swine dysenteri prevent pig sick heal requir product prevent disord respiratori tract product effect swine dysenteri respiratori disord pig belong market treatment swine dysenteri market treatment respiratori disord pig uniform market indic purpos case decid precis market definit narrowest market definit market treatment swine dysenteri domin posit creat strengthen parasiticid parasiticid turn subdivid ectoparasiticid control extern parasit flea tick endoparasiticid control intern parasit worm ectoparasiticid endoparasiticid administ small farm anim divis rise separ product market farm anim ectoparasiticid farm anim endoparasiticid small anim ectoparasiticid small anim endoparasiticid respect product classif differ term effect formul composit frequent farm small anim custom typic farmer farm anim consum own household pet small anim similarli depend dispens form activ substanc control intern extern parasit classif characterist intend purpos parti repres distinct relev product market market endoparasiticid affect merger except small anim ectoparasiticid result commiss investig confirm market definit propos parti competit concern identifi result depth examin carri commiss assess small anim ectoparasiticid present separ section anim health product part hygien product consist product intend stabl disinfect sector market product stabl farm fly control affect concentr market includ product control fli premis market control stabl fli differ ectoparasiticid product livestock type insect control ectoparasiticid product livestock effect pest live host anim sting bite transmit diseas stabl fli settl anim short time sting bite stress pose hygien problem competitor consult distinguish ectoparasiticid product livestock stabl fly control answer intim product effect sting bite insect effect stabl fli overlap ectoparasiticid product livestock product stabl substitut consider competit assess manufactur anim health product requir activ substanc parti opinion activ substanc substitut tiamulin substitut activ substanc anim antibiot tiamutin mark belong sandoz end product manufactur tiamulin treat broad rang infecti diseas parti mention seri activ substanc substitut tiamulin observ crop protect sector part commiss establish activ substanc basic substitut substitut activ substanc rise product formul test effect registr appli take consider amount time substitut activ substanc assum statement valid anim health sector relev geograph market anim health product subject nation approv measur price differ member state consider indic product price close align recent year similarli distribut channel differ countri great britain distribut ensur veterinari agricultur wholesal franc ensur pharmaceut wholesal inform receiv market european european extent gener manufactur product vari member state manufactur central product instal distribut countri europ world ciba manufactur product question great britain unit state switzerland addit council regul eec nr lai uniform author procedur commun level activ substanc requir manufactur anim health product manufactur crop protect product larg undertak good market intellig purchas substanc europ world market activ substanc european basi inform commiss believ definit relev market anim health product nation definit market activ substanc european ectoparasiticid product livestock product stabl market treatment swine dysenteri definit relev geograph market left open narrowest definit nation market broader definit domin posit creat strengthen concentr small anim ectoparasiticid concern refer made part competit assess activ substanc competitor point activ substanc tiamulin product treat swine dysenteri manufactur sandoz ciba concentr give rise monopoli tiamulin manufactur activ ingredi vertic integr enterpris sell product parti manufactur end product anim health sector crop protect possibl health care section deal pharmaceut commiss establish ciba sandoz manufactur activ ingredi exclus intern part section crop protect ciba sell ingredi parti commod activ ingredi longer protect patent parti confirm sell tiamulin parti concentr chang actual competit situat market activ ingredi tiamulin ectoparasiticid product livestock inform suppli parti notif market ectoparasiticid product livestock great britain affect concentr combin market share ciba sandoz submiss parti correct data sandoz market share great britain sandoz sell formul product activ substanc propetampho grampian formul sandoz present market finish product great britain addit manufactur activ substanc suppli bui nippon kayaku japan regard concentr potenti competitor sandoz drop continu present market bayer market share sharp gain grampian sharp increas mallinckrodt hoechst msd merck sharp dome pfizer small market share commiss investig show parti figur market share high estim sandoz activ upstream market activ substanc distributor ciba market share order larg number strong competitor commiss reach conclus domin posit creat strengthen market concentr product stabl inform provid parti notif market product stabl franc affect merger combin market share amount ciba sandoz sandoz distribut product firm account parti calcul market share initi check carri commiss affect market great britain denmark spain franc belgium germani itali combin market share amount germani great britain submiss present initi proceed parti argu virtual imposs determin exact market volum product stabl argu ciba sandoz account assess product market overview individu countri reason type product stabl suffici account origin estim market volum great britain includ environ sprai aerosol actual market volum great britain ecu million ecu million parti market share amount term market volum estim ecu million ecu million similar reason market volum itali underestim parti combin market share amount belgium sandoz market product rate temporarili meant massiv loss market share belgium longer affect market inform german market longer affect merger competitor survei commiss put market volum level case higher estim parti reason number overlap livestock ectoparasiticid stabl fly control assum parti market share overestim sum relev market product stabl franc ciba sandoz great britain ciba sandoz denmark ciba sandoz spain ciba sandoz itali ciba sandoz market structur relev market stabl fly control ciba strong market posit market share amount market share sandoz transfer novarti small sandoz gain market share denmark maintain share relev market franc massiv loss market share loss similarli ciba lost market share franc lost market share denmark ciba gain relev market franc competitor bayer market share fairli substanti growth mallinckrodt market share loss sogev larg number competitor small market share denmark parti competitor mallinckrodt market entri market share estromat gain kvk market share loss larg number competitor small market share itali parti competitor bayer market share suffer market share loss hoechst copyr competitor smaller market share similar pattern larger competitor larg number smaller competitor market share fluctuat time emerg spain competitor largest market share parti estev bayer fact show parti merger market leader member state event face strong competitor larg number smaller competitor distinct fluctuat market share time indic intens competit product potenti competit market product stabl shown slight growth case shrunk gener anticip product continu futur market reason fli develop resist activ substanc short time year make develop product parti put cost develop product stabl ecu million manufactur distribut network launch product entail major addit cost manufactur distribut network sell product intermediari parti sandoz distribut end larg firm competitor competitor oper member state face major entri barrier nation market manufactur product differ member countri registr product plant protect author respons take month maximum year depend member state question potenti competitor respect bayer mallinckrodt hoechst account fact overlap livestock ectoparasiticid market stabl fly control grampian pitman moor american cyanamid msd merck sharp dome pfizer potenti competitor market entri costli gener manufactur manufactur prove product ident qualiti author product entrust manufactur gener subcontractor establish product facil gener manag establish rule market entri gener manufactur occur product base activ ingredi resist problem parti mention gener manufactur farnharn fermon troi biosienc denka enter french market stabl fly control demand condit product stabl fly control sold parti nation compani parti distribut entrust sanofi end agricultur cooper wholesal turn sell product dealer parti parti establish clientel plant protect area larg ident market stabl fly control state discuss plant protect appli parti increas product price significantli custom turn competitor product threaten obtain futur suppli herbicid insecticid fungicid parti competitor parti room manoeuvr set price effect restrict research develop assess effect parti amp potenti futur competit relationship confin stabl fly control broader framework overlap livestock ectoparasiticid substanc fall plant protect area insecticid effect parasit stabl fli anim health product sector ciba sandoz invest total turnov research develop averag sector major competitor recent year develop activ substanc engag research develop activ case bayer hoechst rhône mérieux pfizer msd american cyanamid case compani ectoparasiticid core segment activ health care plant protect area give rise synergi activ anim health sector research anim health sector substanc plant protect research lesser extent research health care order test suitabl combat anim diseas insect substanc larg extent obtain extern sourc univers compani addit synergi case achiev abovement competitor parti deriv advantag size amp divis cf part critic mass reach amp activ hold prospect success abovement competitor parti achiev critic mass summari market stabl fly control parti case market share market leader market product stabl small market share addit market share fluctuat time product launch expect presenc instanc strong competitor larg number smaller competitor possibl strong competitor enter nation market hitherto oper countervail power custom presenc competitor strong amp area show merger creat strengthen domin posit market market treatment swine dysenteri parti determin turnov market share market prepar treatment diseas indic establish parti argu custom purchas product treatment prevent respiratori diseas dysenteri sandoz turnov europ tiamutin includ sale indic anti infectiva poultri parti assum sandoz market share order individu countri treatment swine dysenteri rule possibl greec itali member state ciba suppli product base tiamulin dynamutilin combin market share commiss investig produc precis figur suggest parti posit market order magnitud product treatment swine dysenteri suppli upjohn pharmacia dow elanco larg number gener manufactur product gener base tiamulin base activ substanc lincomycin lincomycin spectinomycin tylosin metronidazol activ substanc longer cover patent protect produc gener manufactur patent protect tiamulin expir europ except franc sandoz patent extend shortli parti produc tiamulin formul product tiamulin todai manufactur equival qualiti level archemia geopharma milan sandoz ciba archemia export tiamulin market treatment swine dysenteri small market doubt archemia suppli market demand competitor year parti produc tiamulin satisfactori qualiti market entri expect prospect profit market posit parti product swine dysenteri treatment respiratori diseas disord digest tract pig poultri parti posit rais price product sole market treatment swine dysenteri price increas product market parti posit strong parti estim combin market share segment end product base tiamulin probabl result market share loss impact earn situat parti room manoeuvr set price restrict reason price increas lead market entri reason strong competitor product base activ ingredi tiamulin larg number gener manufactur limit room manoeuvr set price probabl market entri parti increas price commiss conclud merger creat strengthen domin posit market treatment swine dysenteri narrow product market definit fact applic small anim ectoparasiticid sae relev product market light comment receiv competitor commiss understand oper sae commiss consid simplist small anim ectoparasidicid constitut homogen relev product market effect underestim strength merg parti market posit segment sea product market sae product market compris number segment split main wai place product administ anim environ anim ii natur product adulticid kill adult parasit larva igr insect growth regul essenti steril break reproduct cycl linkag breakdown adulticid appli typic anim flea collar dust powder shampoo spot applic igr appli anim environ break flea reproduct cycl effect absolut deal potenti flea problem anim environ adulticid appli anim igr appli environ market evolv product sophist innov result simplist characterist divis break innov ciba product call program igr administ anim pill form evid collect commiss competitor confirm adulticid igr consid full substitut igr effect adult parasit adulticid igr true argu parti dead flea lai egg sidestep issu approach conceptu complet adulticid short term solut igr instrument long term solut repeat applic adulticid treat problem sourc flea reproduct adulticid igr complementari product competitor survei bayer hoechst mallinckrodt pfizer rhône mérieux sanofi virbac half consid adulticid igr substitut remain view adulticid igr clinic substitut state practic treatment complement provid rapid effect solut competitor intend develop anim igr order complet sae portfolio combin product competitor point develop combin product adulticid igr combin short term advantag adulticid kill initi flea popul long term advantag igr combat flea reproduct combin product gain ground term repres small proport market inform provid parti combin product market europ sprai aerosol type appli environ anim commiss opinion exist adulticid igr combin sae product indic substitut product contrari serv conform address aspect flea problem underlin complementari natur igr adulticid price comparison notifi parti provid price data adulticid british irish dutch market price comparison carri basi monthli cost treat anim result gt tabl gt gt tabl gt gt tabl gt basi igr program significantli expens main adulticid tiguvon frontlin result fulli conclus view remark pulvex footnot insignific price competit igr program hand adulticid tiguvon frontlin distribut channel commiss draw signific distinct sae product distribut vet otc sector counter shop retail store supermarket divis sae market true recent expens product tend sold vet period year provid complic emerg otc sector buyer access distribut channel larg ident product obtain conclus definit product market light inform conclus drawn clear undisput product market definit statement made igr poor substitut adulticid short term initi applic program combin adulticid clinic condit igr adulticid break flea reproduct cycl effect anti flea treatment practic requir aspect long short term address major competitor igr adulticid substitut remain major recogn complementari natur igr adulticid desir competit term complet product rang igr exist combin product evid complementari natur igr adulticid market sophist essenti competitor manufactur igr turn mean access activ ingredi requir develop product analysi competit relat carri level sae market import igr futur develop market account parti combin posit regard market segment geograph refer market parti clear trend europ wide market refer measur aim harmon nation law commun point introduct standard commun registr procedur creation european medic evalu agenc product manufactur central product facil sold european countri claim price differ member state increasingli level commiss acknowledg integr trend consid condit competit suffici homogen conclus drawn commun wide market nation registr approv requir appli consider variat competitor market share member state differ remain distribut arrang sandoz sell product member state competitor accur price comparison cross border basi complic product heterogen price differ order case number lead sae product view evid nation market major competitor present member state activ ingredi case licens parti member state proper competit assess regard wider dimens fact relat area commiss identifi ground concern igr activ ingredi nation posit import regard posit european world level competit assess market structur sae market fairli larg fairli small competitor larg number smaller player sell simpl unsophist product otc sector parti unabl provid market share data nation level broken adulticid igr parti point extrem difficulti deriv accur market share data fact initi data provid parti correct reflect product manufactur sandoz market parti sanofi seek carri analysi futur market posit merg parti commiss oblig adopt pragmat approach revis correct market share data provid parti distinguish igr adulticid segment nation level affect product market great britain ireland netherland market share total market parti estim gt tabl gt gt tabl gt gt tabl gt novarti result merger lead market player market great britain import competitor bayer rhône mérieux strong growth sae market evid total market volum doubl nation market space year great britain present largest market commiss focu attent market probabl light market share data parti igr market share higher member state event analysi situat great britain regard indic broader pictur european level parti posit market great britain strong figur market share competitor bayer rhône mérieux mallinckrodt figur show global level parti combin market share approxim time greater competitor time greater competitor great britain extrem small market share commiss investig sell simpl unsophist product pictur broadli confirm confidenti data publish british veterinari institut cover distribut vet imposs estim size otc market commiss investig signific competitor otc market figur bvi list commiss estim bvi data cover total british market bvi market share quarter iv gt tabl gt bvi data ciba sandoz clear market leader half market commiss sanofi pfizer independ competitor sanofi pfizer sell product brand product manufactur sandoz sanofi pfizer organ market distribut brand market distribut resourc sandoz enjoi merger ciba incent continu contract expiri current contract fact sandoz termin distribut contract sanofi farm fly product commiss awar june sandoz gave notic termin exist distribut contract competitor true virbac sell product emploi igr activ ingredi sandoz methopren pyriproxifen suppli sumitomo fenoxycarb produc suppli ciba addit virbac depend activ ingredi adulticid diazin manufactur ciba event virbac smaller compani novarti compar financi resourc biggest competitor bayer bayer purchas activ ingredi novarti bayer purchas methopren sandoz fur product bolfo major contractu link merg parti biggest competitor strength novarti market posit contractu link novarti bayer area igr novarti strength question bayer compet significantli novarti igr segment prove extrem difficult secur accur market share data igr adulticid product data parti provid give breakdown adulticid igr european level gt tabl gt parti argu igr product combin product consid separ segment result parti segment consid affect market commiss accept posit parti claim substitut adulticid igr submiss substitut possibl igr product combin product commiss receiv competitor estim combin ciba sandoz igr market share number member state gt tabl gt market share igr segment establish certainti reason parti share european level region ciba sell program great britain product igr activ ingredi lufenuron sandoz directli present market great britain sell combin product competitor sanofi sanofi sell acclaim combin product manufactur sandoz sanofi sandoz igr activ ingredi methopren similarli pfizer market canovel combin product sandoz igr activ ingredi methopren ciba program success igr usa treat environment problem anim case igr sold europ environ avoid difficulti involv adulticid igr environ lack conveni problem complianc applic instruct pet owner applic involv effort applic success difficulti access affect part larg area treat health hazard caus sprai anim ciba conduct major advertis campaign program unit state signific attach market develop unit state foreshadow develop europ program sale europ market ciba invest signific resourc product advertis scale ciba success unit state shown tabl gt tabl gt commiss find hoechst mallinckrodt rhône mérieux sell igr product pure combin form great britain europ bayer anim igr shown import relat futur market develop major current competitor state trend anim igr seventh acknowledg success program anim igr present time compani confirm anim igr superior anim igr confirm possess anim igr develop product seventh appear commiss awar avail product market place conclud possess igr crucial import competitor secur futur market posit respect loss potenti competit ciba sandoz import commiss understand sandoz develop anim igr methopren activ ingredi sale activ ingredi vital import factor competit assess degre suppli activ ingredi novarti market competitor contrast market plant protect sector part evid sae field igr adulticid activ ingredi suppli arrang side novarti competitor vice versa commiss awar adulticid igr ingredi purchas novarti competitor commiss igr segment identifi activ ingredi igr produc gt tabl gt activ ingredi control merg parti sandoz suppli methopren indirectli contain deliv end product sanofi pfizer directli bayer merger conclud incent novarti continu suppli market structur commiss investig major competitor imposs secur suppli activ ingredi american cynamid sumitomo potenti entri altern suppli sourc methopren commiss acknowledg methopren longer cover patent protect major problem find valid altern gener supplier methopren appear difficulti secur supplier parti identifi potenti supplier hungari commiss find egi pharmaceut suppli methopren finish product babolna bio suppli methopren competitor doubt suppli kind methopren potenti requir exist custom sandoz methopren improv formul longer last effect todai manufactur sandoz gener manufactur hungari china clinic term equal sandoz product market fact competitor member state purchas gener prove methopren manufactur hungari china adequ altern sandoz activ ingredi potenti supplier suppli product requir specif inform manufactur gener present possess achiev puriti standard methopren activ ingredi end product regist exist call masterfil inform applic nation author registr masterfil properti enterpris appli registr access masterfil grant parti patent expir problem delai caus regulatori author conduct trial valid safeti efficaci finish product substitut activ materi gener commiss enquiri confirm methopren todai desir quantiti averag year develop anim igr demand side bargain power demand side extrem fragment individu consum purchas product vet pet shop commiss consid signific demand side bargain power exist parti invok conclus novarti market strength sae market igr coupl competitor depend continu suppli activ ingredi methopren suffici probabl novarti adequ constrain competitor futur merger creat domin posit market undertak propos merg parti parti recogn commiss concern regard novarti futur market posit relat suppli methopren order remov concern propos undertak undertak declar willing behalf novarti ag provid time period year merger constitut novarti interest parti applic small anim ectoparasiticid sale europ exclus unlimit licenc product activ ingredi rs methopren license access technic data master file term licenc fair reason turnov relat licenc fee exceed durat exceed year initi contribut payabl cover cost offset licenc fee turnov license realiz product activ ingredi licenc fee calcul part product methopren time conclus contract commenc product license subject maximum period year novarti suppli methopren license normal market condit assess propos undertak merger parti acquir extrem strong posit market sae igr activ ingredi critic futur market develop suppli number market competitor ciba enjoi patent right respect igr activ ingredi lufenuron fenoxycarb sandoz held origin right methopren expir applic prolong patent respect methopren pend sandoz manufactur worldwid methopren possess valuabl technic process propos undertak enabl competitor purchas licenc product rs methopren result advers competit consequ caus combin ip right igr activ ingredi avoid methopren remain market place competitor develop gener igr complet technic packag incorpor detail master file made competitor facilit develop methopren base igr competitor grant licenc maintain market access produc compet signific advantag novarti time exist competitor abil free suppli depend novarti methopren rs type implement busi strategi sae sector unconstrain suppli depend novarti methopren light commiss consid novarti lead sae produc europ enjoi strong market posit longer forese suffici probabl merg parti behav signific extent independ competitor order enabl commiss monitor implement undertak year period parti requir submit monthli report inform methopren licenc request receiv methopren licenc request grant methopren licenc request grant reason refus detail methopren rs suppli form activ ingredi contain finish product parti seed definit product market product seed involv breed develop progag product market seed seed type plant sugarbeet maiz wheat barlei grape type seed mutual substitut constitut relev product market iv zeneca vanderhav point competitor suggest market defin narrow term farmer basi criteria decid grow type crop choos type seed cultiv crop select depend climat condit soil seed region interchang seed relev product market region differenti seed type effici competitor produc seed region suffici purpos case delimit market differenti region seed type product seed stage breed commerci product iv zeneca vanderhav point seq commerci product seed subdivid stage seed cultiv seed firm basic seed propag contract cooper farmer unpurifi finish seed propag seed purifi sort pack seed compani process plant undertak manufactur stage describ defin parti separ product market seed remain properti seed compani entir prepar process bought sold market propag basic seed cooper farmer suppli servic seed compani occasion exchang breed materi germplasm order develop improv basic seed common hybrid develop process line undertak cross activ practis undertak activ undertak receiv licenc fee germplasm increas renew individu seed compani long process breed compar intang properti chemic engin industri patent germplasm sold parti competitor parti inform competitor undertak produc seed reli germplasm foundat seed hous institut special collect germplasm produc undertak distribut undertak cross market germplasm mention parti sell germplasm parti activ market geograph market market seed earn potenti seed decis motiv bui seed climat soil condit vari region region differenti seed produc highest return product requir differenti region climat zone iv zeneca vanderhav point seq seed sold regist member state registr appli seed match requir includ nation list automat european catalogu subsequ sold commun addit parti figur show seed suppli member state price seed compani produc seed member state countri europ export import quota correspondingli high purpos case definit geograph refer market left open narrowest nation wider definit seed market domin posit creat strengthen point seed cultiv climat zone market propag seed defin climat zone extent zone cross nation border europ climat zone distinguish latitud european market suppli extent seed develop produc propag corn belt unit state geograph delimit climat zone includ similar zone world competit assess market propag seed market propag seed thousand agricultur cooper farmer provid propag servic incom cooper farmer earn provid servic small secondari econom import case maiz seed overlap result concentr small scale effect concentr competit relat market propag seed seed maiz seed small seed produc present market farmer choic reason abus buyer concentr power market propag seed domin posit creat strengthen market seed market structur market share parti attain concentr exce market grain maiz seed greec ciba sandoz grain maiz seed spain ciba sandoz gain market share small market posit parti strengthen margin concentr underscor fact sandoz market share fallen greec exceed spain year ciba strong market posit share remain roughli constant spain doubl greec import competitor pioneer market share greec spain greec pioneer lost market share gain spain period major competitor greec limagrain market share limagrain activ spain market share tini present spain zeneca market share articl notifi merger ciba geigi ag sandoz ag declar compat common market function eea agreement subject condit undertak parti set point fulfil articl parti report commiss accord point decis articl decis address ciba geigi ag ch basel sandoz ag ch basel brussel juli commiss karel van miert member commiss oj corrigendum oj oj omit reason busi secreci differ cost reimburs social secur system plai role introduct central european registr pre sow herbicid appli soil immedi seed sown pre emerg treatment herbicid appli immedi germin dai sow post emerg herbicid appli soil plant germin oj oj omit reason busi secreci replac rang public purpos oj affect nation market identifi parti level sae market commiss acknowledg data provid parti contain adulticid produc mallinckrodt pulvex netherland index nich product relat mallinckrodt market posit gener market size ecu million parti identifi sixth triflumuron own bayer bayer prefer licens altern pyriproxyfen methopren product supplier worldwid commiss awar tianjin institut pesticid china supplier mention compani sourc event consid suffer handicap potenti hungarian supplier