VDX
VDX may refer to:

 VDX (library software) (for Virtual Document eXchange), an interlibrary loan software product
 .vdx, a filename extension for the Microsoft Visio XML drawing file format
 OSEK or OSEK/VDX (Vehicle Distributed eXecutive), a standards body for automotive electronics
 Virtual Desktop Extender, by RES Software, acquired by Ivanti in 2017