<s>[INST] Binomial related problem $\left( {\begin{array}{*{20}{c}}
5\\
0
\end{array}} \right)\left( {\begin{array}{*{20}{c}}
{50}\\
5
\end{array}} \right) - \left( {\begin{array}{*{20}{c}}
5\\
1
\end{array}} \right)\left( {\begin{array}{*{20}{c}}
{40}\\
5
\end{array}} \right) + \left( {\begin{array}{*{20}{c}}
5\\
2
\end{array}} \right)\left( {\begin{array}{*{20}{c}}
{30}\\
5
\end{array}} \right) - \left( {\begin{array}{*{20}{c}}
5\\
3
\end{array}} \right)\left( {\begin{array}{*{20}{c}}
{20}\\
5
\end{array}} \right) + \left( {\begin{array}{*{20}{c}}
5\\
4
\end{array}} \right)\left( {\begin{array}{*{20}{c}}
{10}\\
5
\end{array}} \right) = $
Where ${}^n{C_r} = \left( {\begin{array}{*{20}{c}}
n\\
r
\end{array}} \right)$
My approach is as follow $\left( {\begin{array}{*{20}{c}}
5\\
0
\end{array}} \right)\left( {\begin{array}{*{20}{c}}
{50}\\
5
\end{array}} \right) - \left( {\begin{array}{*{20}{c}}
5\\
1
\end{array}} \right)\left( {\begin{array}{*{20}{c}}
{40}\\
5
\end{array}} \right) + \left( {\begin{array}{*{20}{c}}
5\\
2
\end{array}} \right)\left( {\begin{array}{*{20}{c}}
{30}\\
5
\end{array}} \right) - \left( {\begin{array}{*{20}{c}}
5\\
3
\end{array}} \right)\left( {\begin{array}{*{20}{c}}
{20}\\
5
\end{array}} \right) + \left( {\begin{array}{*{20}{c}}
5\\
4
\end{array}} \right)\left( {\begin{array}{*{20}{c}}
{10}\\
5
\end{array}} \right) = \sum\limits_{r = 0}^4 {{{\left( { - 1} \right)}^r}.{}^5{C_r}.{}^{50 - 10r}{C_5}} $
Using the technique of some previous problem I tried to solve by absorption
$\sum\limits_{r = 0}^4 {{{\left( { - 1} \right)}^r}.\frac{{5!}}{{r!\left( {5 - r} \right)!}}.\frac{{\left( {50 - 10r} \right)!}}{{5!\left( {45 - 10r} \right)!}}}  = \sum\limits_{r = 0}^4 {{{\left( { - 1} \right)}^r}.\frac{{\left( {45 - 9r} \right)!}}{{r!\left( {45 - 10r} \right)!}}.\frac{{\left( {50 - 10r} \right)!}}{{\left( {5 - r} \right)!\left( {45 - 9r} \right)!}}}  \Rightarrow \sum\limits_{r = 0}^4 {{{\left( { - 1} \right)}^r}.{}^{45 - 9r}{C_r}.{}^{50 - 10r}{C_{5 - r}}} $
Not able to proceed further
 [/INST] HINT:
In your expression , what we are looking for  is the sum of the coefficients of the term $x^5$ in the expansion of $$-\bigg[\bigg(1-(1+x)^{10}\bigg)^5 -1\bigg]$$
Because :

*

*$$[x^5][\bigg(1-(1+x)^{10}\bigg)^5 =\sum_{k=0}^{5}-\binom{5}{0}[(1+x)^{10}]^5+\binom{5}{1}[(1+x)^{10}]^4-\binom{5}{2}[(1+x)^{10}]^3...+\binom{5}{5}[(1+x)^{10}]^0$$
To render this expression into yours , subtract the last term , and multiply by $(-1)$
</s>