Learning disabilities and developmental delays are often seen in children with NARP, and older individuals with this condition may experience a loss of intellectual function (dementia). Other features of NARP include seizures, hearing loss, and abnormalities of the electrical signals that control the heartbeat (cardiac conduction defects). These signs and symptoms vary among affected individuals.
Neuropathy, ataxia, and retinitis pigmentosa
Uveitis–Glaucoma–Hyphema syndrome
Multifocal choroiditis and panuveitis
Retinal vasculopathy with cerebral leukoencephalopathy and systemic manifestations
Erythrokeratodermia with ataxia
Tubulointerstitial nephritis and uveitis
Arthrogryposis–renal dysfunction–cholestasis syndrome
Cerebellar ataxia, neuropathy, vestibular areflexia syndrome