The diagnosis may be suspected on the basis of the constellation of clinical features. It is made by sequencing the MAFB gene. Classification This condition has been classified into five types. * Type 1: hereditary<unk><unk>  with dominant transmission * Type 2: hereditary<unk><unk>  with recessive transmission * Type 3: nonhereditary<unk><unk>  with nephropathy * Type 4: Gorham–Stout syndrome Differential diagnosis The condition should be differentially diagnosed from juvenile rheumatoid arthritis and other genetic skeletal dysplasias as<unk><unk> , Nodulosis, and Arthropathy.
Multicentric carpotarsal osteolysis syndrome
Fibrous ankylosis
Tarsal tunnel syndrome
Heel pad syndrome
Duane-radial ray syndrome
Anterior interosseous syndrome
Corneodermatoosseous syndrome
Adducted thumb syndrome