Individuals with the disorder have a mutation to their fibrinogen gene that prevents the formation of the protein. In normal conditions, fibrinogen is converted to fibrin when it is cleaved by the enzyme thrombin in the blood. The newly formed fibrin forms a fiber-rich network that helps trap red blood cells to start the coagulation process and form a clot. Since there is no fibrinogen present during<unk> , fibrin can not be formed to aid in this process.
Congenital afibrinogenemia
Dysfibrinogenemia
Harris platelet syndrome
Acquired haemophilia
Hypodysfibrinogenemia
Quebec platelet disorder
Gray platelet syndrome
Congenital hypofibrinogenemia