<unk>  (LGS) is a complex, rare, and severe childhood-onset epilepsy. It is characterized by multiple and concurrent seizure types, cognitive dysfunction, and slow spike waves on electroencephalogram (EEG). Typically, it presents in children aged 3–5 years and can persist into adulthood. It has been associated with several gene mutations, perinatal injuries, congenital infections, brain tumors/malformations, and genetic disorders such as tuberous sclerosis and West syndrome. The prognosis for LGS is poor with a 5% mortality in childhood and persistent seizures into adulthood (80%–90%). LGS was named for neurologists William G.<unk>  (Boston, USA) and Henri<unk>  (Marseille, France), who independently described the condition. The international LGS Awareness Day is on November 1.
Lennox–Gastaut syndrome
Goldenhar syndrome
Joubert syndrome
Bardet–Biedl syndrome
Shprintzen–Goldberg syndrome
Benjamin syndrome
Christianson syndrome
Laron syndrome