<unk> 's primary use in medicine is in the treatment of major depressive disorder, especially where sedation is helpful due to its prominent sedative effects. The drug is also an effective anxiolytic, and can be used in the treatment of anxiety. In addition to depression and anxiety,<unk>  is effective in the treatment of insomnia, and unlike most other hypnotics, does not alter the normal sleep architecture. In particular, it does not suppress REM sleep, and dreams are said to "brighten" during treatment.<unk>  also has some weak antipsychotic effects with a profile of activity described as similar to that of clozapine, and may be useful in the treatment of psychotic symptoms such as in delusional depression or schizophrenia. The effective dosage of<unk>  in depression is 150 to 300 mg/day.
Trimipramine
Carpipramine
Clomipramine
Desipramine
Imipramine
Sertraline
Citalopram
Chlorpromazine