A<unk>  (DoLR), also known as a heroic dose, is a pharmaceutical drug which is tried after all other drug options have failed to produce an adequate response in the patient. Drug resistance, such as antimicrobial resistance or antineoplastic resistance, may make the first-line drug ineffective, especially with multidrug-resistant pathogens or tumors. Such an alternative may be outside of extant regulatory requirements or medical best practices, in which case it may be viewed as salvage therapy.
Drug of last resort
First-in-class medication
Generic drug
Prototype drug
Broad-spectrum therapeutic
Venoms in medicine
Over-the-counter drug
Blood substitute