<unk>  is an X-linked neurological disorder that damages oligodendrocytes in the central nervous system. It is caused by mutations in proteolipid protein 1 (PLP1), a major myelin protein. It is characterized by a decrease in the amount of insulating myelin surrounding the nerves (hypomyelination) and belongs to a group of genetic diseases referred to as leukodystrophies.
Pelizaeus–Merzbacher disease
Axenfeld–Rieger syndrome
Kufor–Rakeb syndrome
Zunich–Kaye syndrome
Letterer–Siwe disease
Cornelia de Lange syndrome
Sturge–Weber syndrome
Hurler–Scheie syndrome