Estradiol, the active form of EDE. Pharmacodynamics EDE is an estradiol ester, or a prodrug of estradiol. As such, it is an estrogen, or an agonist of the estrogen receptors. EDE is of about 82% higher molecular weight than estradiol due to the presence of its C3 and C17β heptanoate (enanthate) esters. Because EDE is a prodrug of estradiol, it is considered to be a natural and bioidentical form of estrogen. Pharmacokinetics Estradiol and testosterone levels following a single intramuscular injection of Climacteron (including 1 mg EB, 7.5 mg EDE, and 150 mg TEBH equivalent to 69 mg free testosterone) versus 10 mg estradiol valerate have been studied over 28 days.
Estradiol dienantate
Estradiol undecylate
Estradiol enantate
Estradiol furoate
Estradiol valerate
Estradiol dipropionate
Estradiol hemisuccinate
Estradiol diundecylenate