The term<unk>  refers to subjects in a drug trial that receive no treatment of any kind and whose illness is, as a consequence, left to run its<unk> " course. The term stems from the<unk><unk>  of an illness, which is the course and outcome of that illness in the absence of treatment.
Natural history group
N of 1 trial
Clinical endpoint
Multiple baseline design
Parallel study
Subgroup analysis
Clinical study design
Real world data