<unk>  is a rare genetic developmental defect during embryogenesis disorder and is thought to be hereditary. In 1975 a physician described four siblings in a Dutch family with symptoms of the condition; the condition was named after the oldest sibling. According to Orphanet, the condition occurs in 1 in 1 million people. Children with this condition appear younger than their age.<unk>  can cause disability and death around early or mid adulthood. Sudden death, cardiomyopathy, and heart failure have been reported in some cases.
Nathalie syndrome
Sugarman syndrome
Lenz–Majewski syndrome
Mungan syndrome
Heimler syndrome
GRACILE syndrome
Leigh syndrome
Silver–Russell syndrome