<unk>  (brand name Apoquel) is a veterinary medication used in the control of atopic dermatitis and pruritus from allergic dermatitis in dogs at least 12 months of age. Chemically, it is a synthetic cyclohexylamino pyrrolopyrimidine janus kinase inhibitor that is relatively selective for JAK1. It inhibits signal transduction when the JAK is activated and thus helps downregulate expression of inflammatory cytokines. While<unk>  is effective, its long-term safety is currently unknown.<unk>  was approved by the FDA in 2013.
Oclacitinib
Abrocitinib
Upadacitinib
Baricitinib
Erdafitinib
Delgocitinib
Gilteritinib
Dacomitinib