There are no known significant drug interactions with topical<unk> . However, with oral (troche)<unk> , there are multiple interactions as the medication is a CYP450 enzyme inhibitor, primarily CYP3A4. Thus, any medication that is metabolized by the CYP3A4 enzyme will potentially have elevated levels when oral<unk>  is used. The prescribing physician should be aware of any medication the patient is taking prior to starting oral<unk> . Certain medications should not be taken with oral<unk> .
Clotrimazole
Ipriflavone
Efinaconazole
Itraconazole
Felbinac
Sertaconazole
Terbinafine
Miconazole