<unk> , sold under the brand name Ziagen, is a medication used to prevent and treat HIV/AIDS. Similar to other nucleoside analog reverse-transcriptase inhibitors (NRTIs),<unk>  is used together with other HIV medications, and is not recommended by itself. It is taken by mouth as a tablet or solution and may be used in children over the age of three months.<unk>  is generally well tolerated. Common side effects include vomiting, trouble sleeping, fever, and feeling tired. More severe side effects include hypersensitivity, liver damage, and lactic acidosis. Genetic testing can indicate whether a person is at higher risk of developing hypersensitivity. Symptoms of hypersensitivity include rash, vomiting, and shortness of breath.<unk>  is in the NRTI class of medications, which work by blocking reverse transcriptase, an enzyme needed for HIV virus replication. Within the NRTI class,<unk>  is a carbocyclic nucleoside.<unk>  was patented in 1988, and approved for use in the United States in 1998. It is on the World Health Organization's List of Essential Medicines. It is available as a generic medication. Commonly,<unk>  is used together with other HIV medications, such as<unk> /lamivudine/zidovudine,<unk> /dolutegravir/lamivudine, and<unk> /lamivudine. The combination<unk> /lamivudine is also an essential medicine.
Abacavir
Fosamprenavir
Saquinavir
Coronavir
Entecavir
Fostemsavir
Indinavir
Tipranavir