<unk> s are a tumor of the delta cells of the endocrine pancreas that produces somatostatin. Increased levels of somatostatin inhibit pancreatic hormones and gastrointestinal hormones. Thus,<unk> s are associated with mild diabetes mellitus (due to inhibition of insulin release), steatorrhoea and gallstones (due to inhibition of cholecystokinin release), and achlorhydria (due to inhibition of gastrin release).<unk> s are commonly found in the head of pancreas. Only ten percent of<unk> s are functional tumours 9, and 60-70% of tumours are malignant. Nearly two-thirds of patients with malignant<unk> s will present with metastatic disease.
Somatostatinoma
VIPoma
Glucagonoma
Gastrinoma
Insulinoma
Glomus tumor
Gangliocytic paraganglioma
Metastatic insulinoma