<unk> , or irresponsible<unk> , is<unk>  alcoholic beverages with an intention of becoming intoxicated by heavy consumption of alcohol over a short period of time, but definitions (see below) vary considerably.<unk>  is a style of<unk>  that is popular in several countries worldwide, and overlaps somewhat with social<unk>  since it is often done in groups. The degree of intoxication, however, varies between and within various cultures that engage in this practice. A<unk>  on alcohol can occur over hours, last up to several days, or in the event of extended use, even weeks. Due to the long term effects of excessive alcohol use,<unk>  is considered to be a major public health issue.<unk>  is more common in males, during adolescence and young adulthood. Heavy regular<unk>  is associated with adverse effects on neurologic, cardiac, gastrointestinal, hematologic, immune, and musculoskeletal organ systems as well as increasing the risk of alcohol induced psychiatric disorders. A US-based review of the literature found that up to one-third of adolescents<unk> -drink, with 6% reaching the threshold of having an alcohol-related substance use disorder. Approximately one in 25 women<unk> -drinks during pregnancy, which can lead to fetal alcohol syndrome and fetal alcohol spectrum disorders.<unk>  during adolescence is associated with traffic accidents and other types of accidents, violent behavior as well as suicide. The more often a child or adolescent<unk>  drinks and the younger they are the more likely that they will develop an alcohol use disorder including alcoholism. A large number of adolescents who<unk> -drink also consume other psychotropic substances. Frequent<unk>  can lead to brain damage faster and more severely than chronic<unk>  (alcoholism). The neurotoxic insults are due to very large amounts of glutamate which are released and over-stimulate the brain as a<unk>  finishes. This results in excitotoxicity, a process which damages or kills neurons (brain cells). Each<unk>  episode immediately insults the brain; repeat episodes result in accumulating harm. The developing adolescent brain is thought to be particularly susceptible to the neurotoxic effects of<unk> , with some evidence of brain damage occurring from<unk>  more than 10 or 11 drinks once or twice per month. A 2020 study found that even a single episode of<unk>  can lead to atrophy of the brain's corpus callosum, which damage was still detectable by an MRI scanner five weeks later. With prolonged abstinence neurogenesis occurs which can potentially reverse the damage from heavy alcohol use.
Binge drinking
Rubbing alcohol
Binge eating
Alcoholism
Abuse during childbirth
Alcohol dependence
Western pattern diet
Sedentary lifestyle