A<unk>  overdose may result in a wide range of symptoms. A moderate overdose of<unk>  may induce symptoms such as: abnormal heart rhythm, confusion, difficult and/or painful urination, high or low blood pressure, high body temperature, over-active and/or over-responsive reflexes, muscle aches, severe agitation, rapid breathing, tremor, urinary hesitancy, and an inability to pass urine. An extremely large overdose may produce symptoms such as adrenergic storm,<unk>  psychosis, substantially reduced or no urine output, cardiogenic shock, bleeding in the brain, circulatory collapse, hyperpyrexia (i.e., dangerously high body temperature), pulmonary hypertension, kidney failure, rapid muscle breakdown, serotonin syndrome, and a form of stereotypy ("tweaking"). A<unk>  overdose will likely also result in mild brain damage due to dopaminergic and serotonergic neurotoxicity. Death from<unk>  poisoning is typically preceded by convulsions and coma. Psychosis Use of<unk>  can result in a stimulant psychosis which may present with a variety of symptoms (e.g., paranoia, hallucinations, delirium, and delusions). A Cochrane Collaboration review on treatment for<unk> etamine, dextroamphetamine, and<unk>  use-induced psychosis states that about 5–15% of users fail to recover completely. The same review asserts that, based upon at least one trial, antipsychotic medications effectively resolve the symptoms of acute<unk> etamine psychosis.<unk> etamine psychosis may also develop occasionally as a treatment-emergent side effect. Emergency treatment Acute<unk>  intoxication is largely managed by treating the symptoms and treatments may initially include administration of activated charcoal and sedation. There is not enough evidence on hemodialysis or peritoneal dialysis in cases of<unk>  intoxication to determine their usefulness. Forced acid diuresis (e.g., with vitamin C) will increase<unk>  excretion but is not recommended as it may increase the risk of aggravating acidosis, or cause seizures or rhabdomyolysis. Hypertension presents a risk for intracranial hemorrhage (i.e., bleeding in the brain) and, if severe, is typically treated with intravenous phentolamine or nitroprusside. Blood pressure often drops gradually following sufficient sedation with a benzodiazepine and providing a calming environment. Antipsychotics such as haloperidol are useful in treating agitation and psychosis from<unk>  overdose. Beta blockers with lipophilic properties and CNS penetration such as metoprolol and labetalol may be useful for treating CNS and cardiovascular toxicity. The mixed alpha- and beta-blocker labetalol is especially useful for treatment of concomitant tachycardia and hypertension induced by<unk> . The phenomenon of "unopposed alpha stimulation" has not been reported with the use of beta-blockers for treatment of<unk>  toxicity.
Methamphetamine
Benzphetamine
Amphetamine
Benzyl alcohol
Benzocaine
Cannabis
Cannabis 
Nicotine