In primary CIPO (the majority of chronic cases) the condition results from disruption of the intestine's ability to move food. These can be broadly classified as myopathic (affecting the smooth muscle), mesenchymopathic (affecting the interstitial cells of Cajal), or neuropathic (of the nervous system) of the gastrointestinal tract. In some cases there appears to be a genetic association. One form has been associated with DXYS154. Secondary chronic<unk>  can occur as a consequence of a number of other conditions including: * Hirschsprung's disease - the absence of colonic nerve cells * Chagas' disease - a chronic parasitic infection of the colon leading to loss of nerve endings * Kawasaki disease - a rare presentation for this particular autoimmune disorder of the vasculature * Parkinson's disease - related to the neurodegeneration of gastrointestinal tract * Autoimmune conditions - conditions including systemic lupus erythematosus and scleroderma lead to collagen vascular deposition and gastrointestinal motility disruption * Mitochondrial disease - IPO is a known presentation for mitochondrial disease * Endocrine disorders * Certain medications. The term may be used synonymously with enteric neuropathy if a neurological cause is suspected.
Intestinal pseudo-obstruction
Ovarian cyst
Distal intestinal obstruction syndrome
Crohn's disease
Vesicointestinal fistula
Bowel obstruction
Gastrojejunocolic fistula
Neoplasm