<unk>  is readily absorbed from the gastrointestinal tract. It is distributed to the body with higher levels in the kidney, thyroid, and bone as compared to other tissues. Since<unk>  is almost exclusively excreted by the kidneys, people with preexisting chronic kidney disease are at high risk of developing<unk>  intoxication.<unk>  can be mistaken for other syndromes associated with antipsychotic use, such as serotonin syndrome because<unk>  increases serotonin metabolites in the cerebrospinal fluid. There are several drug interactions with<unk> . Interactions can occur from typical antipsychotics or atypical antipsychotics. In particular, certain drugs enhance<unk>  levels by increasing renal re-absorption at the proximal tubule. These drugs are angiotensin-converting enzyme inhibitors, non-steroidal anti-inflammatory drugs and thiazide diuretics.
Lithium toxicity
Tricyclic antidepressant overdose
Opioid-induced endocrinopathy
Alcohol withdrawal syndrome
Benzodiazepine overdose
Antidepressant discontinuation syndrome
Nicotine withdrawal
Alcohol intoxication