Wound area covered in<unk> . Gauze has also been applied.<unk>  is a broad spectrum antiseptic for topical application in the treatment and prevention of wound infection. It may be used in first aid for minor cuts, burns, abrasions and blisters.<unk>  exhibits longer lasting antiseptic effects than tincture of<unk> , due to its slow absorption via soft tissue, making it the choice for longer surgeries. Chlorhexidine provides superior results with equivalent adverse events. Consequently,<unk>  has found broad application in medicine as a surgical scrub; for pre- and post-operative skin cleansing; for the treatment and prevention of infections in wounds, ulcers, cuts and burns; for the treatment of infections in decubitus ulcers and stasis ulcers; in gynecology for vaginitis associated with candidal, trichomonal or mixed infections. For these purposes<unk>  has been formulated at concentrations of 7.5–10.0% in solution, spray, surgical scrub, ointment, and swab dosage forms; however, use of 10%<unk>  though recommended, is infrequently used, as it is poorly accepted by health care workers and is excessively slow to dry. Because of these critical indications, only sterile<unk>  should be used in most cases. Non-sterile product can be appropriate in limited circumstances in which people have intact, healthy skin that will not be compromised or cut. The non-sterile form of<unk>  has a long history of intrinsic contamination with Burkholderia cepacia (aka Pseudomonas cepacia), and other opportunistic pathogens. Its ability to harbor such microbes further underscores the importance of using sterile products in any clinical setting. Since these bacteria are resistant to<unk> , statements that bacteria do not develop resistance to<unk> , should be regarded with great caution: some bacteria are intrinsically resistant to a range of biocides including<unk> . Antiseptic activity of<unk>  is because of free<unk>  (I2) and<unk>  only acts as carrier of I2 to the target cells. Most commonly used 10%<unk>  delivers about 1-3 ppm of I2 in a compound of more than 31,600 ppm of total<unk>  atoms. All the toxic and staining effects of<unk>  is due to the inactive<unk>  only. Eyes A buffered<unk>  solution of 2.5% concentration can be used for prevention of neonatal conjunctivitis, especially if it is caused by Neisseria gonorrhoeae, or Chlamydia trachomatis. It is currently unclear whether<unk>  is more effective in reducing the number of cases of conjunctivitis in neonates over other methods.<unk>  appears to be very suitable for this purpose because, unlike other substances, it is also efficient against fungi and viruses (including HIV and Herpes simplex). Pleurodesis It is used in pleurodesis (fusion of the pleura because of incessant pleural effusions). For this purpose,<unk>  is equally effective and safe as talc, and may be preferred because of easy availability and low cost. Alternatives There is strong evidence that chlorhexidine and denatured alcohol used to clean skin prior to surgery is better than any formulation of<unk>
Povidone-iodine
Amylmetacresol
Diethylstilbestrol disulfate
Diethylstilbestrol dilaurate
Ibotenic acid
Palifermin
Diethylstilbestrol diacetate
Diethylstilbestrol dipropionate