<unk>  is an inflammation of the islets of Langerhans, a collection of endocrine tissue located in the pancreas that helps regulate glucose levels, and is classified by specific targeting of immune cell (T and B lymphocytes, macrophages and dendritic cells) infiltration in the islets of Langerhans. This immune cell infiltration can result in the destruction of insulin-producing beta cells of the islets, which plays a major role in the pathogenesis, the disease development, of type 1 and type 2 diabetes.<unk>  is present in 19% of individuals with type 1 diabetes and 28% of individuals with type 2 diabetes. It is know that genetic and environmental factors contribute to<unk>  initiation, however, the exact process that causes it is unknown.<unk>  is often studied using the non-obese diabetic (NOD) mouse model of type 1 diabetes. The chemokine family of proteins may play a key role in promoting leukocytic infiltration into the pancreas prior to pancreatic beta-cell destruction.
Insulitis
Cellulitis
Sialidosis
Heat edema
Alcohol tolerance
Adiposis dolorosa
Steatosis
Visual snow