<unk>  can be effectively treated with dopaminergic agents (pramipexole, ropinirole, cabergoline, and rotigotine) and it has been found that patients with a low ferritin level respond well to oral iron supplements. Adverse effects of these agents have been reported and include the occurrence of restless leg syndrome triggered by the medication, as well as cortical arousals, which are a cause of disturbed sleep. Patients must stay on these medications in order to experience relief, because there is no known cure for this<unk> . PLMs tend to be exacerbated by tricyclic antidepressants, SSRIs, stress, and sleep deprivation. It is also advised not to consume caffeine, alcohol, or antidepressants as these substances could worsen the<unk>  symptoms. Other medications aimed at reducing or eliminating the leg jerks or the arousals can be prescribed. Non-ergot derived dopaminergic medications (pramipexole and ropinirole) are preferred. Other dopaminergic agents such as co-careldopa, co-beneldopa, pergolide, or lisuride may also be used. These medications decrease or eliminate both the leg jerks and the arousals. These medications are also successful for the treatment of restless legs syndrome. In one study, co-careldopa was superior to dextropropoxyphene in decreasing the number of leg kicks and the number of arousals per hour of sleep. However, co-careldopa and, to a lesser extent, pergolide may shift the leg<unk> s from the nighttime to the daytime. Clonazepam in doses of 1mg has been shown to improve objective and subjective measures of sleep. Hypothesis was presented for supplementation of magnesium use for<unk>  improvement due to evidence for therapeutic effects of magnesium on normal magnesium level patients with insomnia and RLS. Evidence of magnesium on pathomechanisms of<unk>  has yet to be found. However, it remains insufficient evidences related to the efficacy of pharmacological treatment in<unk> , and its use has been based on the dopaminergic medication effect on RLS. Therefore, a careful clinical monitoring with any pharmacological use in<unk>  is recommended.
Periodic limb movement disorder
Periodic paralysis
Cramp fasciculation syndrome
Essential tremor
Holmes tremor
Torsion dystonia
Lonomia
Oromandibular dystonia