<unk> s: * Occur naturally as venoms and poisons (e.g onchidal) * Are used as weapons (nerve agents) * Are used medicinally: * To treat myasthenia gravis. In myasthenia gravis, they are used to increase neuromuscular transmission. * To treat glaucoma * To treat postural tachycardia syndrome * As an antidote to anticholinergic poisoning * To reverse the effect of non-depolarising muscle relaxants * To treat neuropsychiatric symptoms of diseases such as Alzheimer's disease, particularly apathy * To increase chances of lucid dreaming (by prolonging REM sleep) * To treat Alzheimer's disease, the Lewy body dementias and Parkinson's disease. In these neurodegenerative conditions<unk> s are primarily used to treat the cognitive (memory and learning deficits mostly) symptoms of dementia. These symptoms are attenuated due to the role of acetylcholine in cognition in the CNS. There is some evidence to suggest that<unk> s may attenuate psychotic symptoms (especially visual hallucinations) in Parkinson's disease. * To treat cognitive impairments in patients with schizophrenia. There is some evidence to suggest efficacy in treating positive, negative and affective symptoms. * As a treatment for autism and to increase the percentage of rapid eye movement sleep in autistic children, in line with the mechanism by which they encourage lucid dreaming. * Are used as (e.g malathion): * : The hunt for resistance genes in Rhipicephalus microplus has been hampered by high copy number in the three<unk>  involved. Bellgard et al 2012, Temeyer et al 2012, and Bendele et al 2015 all investigate such populations and encounter difficulty confirming the involvement of these three due to copy number.
Acetylcholinesterase inhibitor
Cholinesterase inhibitor
Monoamine oxidase inhibitor
GABA analogue
GABA reuptake inhibitor
Glycine reuptake inhibitor
Adenosine reuptake inhibitor
Opioid antagonist