In bacteria, antibacterial<unk>  act as competitive inhibitors of the enzyme dihydropteroate synthase (DHPS), an enzyme involved in folate synthesis.<unk>  are therefore bacteriostatic and inhibit growth and multiplication of bacteria, but do not kill them. Humans, in contrast to bacteria, acquire folate (vitamin B9) through the diet. PABA (center) is the basis for the inhibitory activity of sulfa drugs on tetrahydrofolate (right) biosynthesis.<unk>  are used to treat allergies and coughs, as well as having antifungal and antimalarial functions. The moiety is also present in other medications that are not antimicrobials, including thiazide diuretics (including hydrochlorothiazide, metolazone, and indapamide, among others), loop diuretics (including furosemide, bumetanide, and torsemide), acetazolamide, sulfonylureas (including glipizide, glyburide, among others), and some COX-2 inhibitors (e.g., celecoxib). Sulfasalazine, in addition to its use as an antibiotic, is also used in the treatment of inflammatory bowel disease.
Sulfonamide 
Quinolone antibiotic
Anthopleurin
Cephalosporin
Lipase inhibitors
Polypeptide antibiotic
Steroid ester
Cephalotribe