<unk>  <unk> -OH-CPA) is a steroidal antiandrogen and the major metabolite of cyproterone<unk>  (CPA). It is formed from CPA in the liver by hydroxylation via the cytochrome P450 enzyme CYP3A4. During therapy with CPA,<unk> -OH-CPA circulates at concentrations that are approximately twice those of CPA.<unk> -OH-CPA has similar or even greater antiandrogen activity compared to CPA. However, it has only about one-tenth of the activity of CPA as a progestogen.<unk> -OH-CPA also shows some glucocorticoid activity, similarly to CPA and unesterified cyproterone.
15β-Hydroxycyproterone acetate
Desoxymethyltestosterone
5α-Dihydrolevonorgestrel
Ethyltestosterone
Cyproterone acetate
Vinyltestosterone
Acetothiolutamide
5α-Dihydronandrolone