The<unk>  is induced by epidermolytic exotoxins (exfoliatin) A and B, which are released by S. aureus and cause detachment within the epidermal layer, by breaking down the desmosomes. One of the exotoxins is encoded on the bacterial chromosome, while the other is encoded on a plasmid. These exotoxins are proteases that cleave desmoglein-1, which normally holds the granulosum and spinosum layers together, similar to the pathophysiology of the autoimmune<unk>  disease, pemphigus vulgaris.
Staphylococcal scalded skin syndrome
Stevens–Johnson syndrome
Streptococcal intertrigo
Toxic epidermal necrolysis
Papular purpuric gloves and socks syndrome
Pemphigus vegetans
Acute cutaneous lupus erythematosus
Shingles