<unk> <unk>  is a<unk>  parenchymal lung disease which often presents with symptoms of cough and shortness of breath. The pathological definition published by the World Health Organization is “a generalized proliferation of scattered single cells, small nodules (neuroendocrine bodies), or linear proliferations of pulmonary neuroendocrine (PNE) cells that may be confined to the bronchial and bronchiolar epithelium.” The true prevalence of this disease is not known. To date, just under 200 cases have been reported in the literature. However, with an increase in recognition of this disease by radiologists and pulmonologists, the number of cases has been increasing.<unk>  predominantly affects middle-aged women with slowly progressive lung obstruction.<unk>  is usually discovered in one of two ways: 1) as an unexpected finding following a lung surgery; or 2) by evaluation of a patient in a pulmonary clinic with longstanding, unexplained symptoms.
Diffuse idiopathic pulmonary neuroendocrine cell hyperplasia
Granulomatous–lymphocytic interstitial lung disease
Pulmonary atypical adenomatous hyperplasia
Atypical pulmonary carcinoid tumour
Mycobacterium avium-intracellulare infection
Pulmonary neuroendocrine tumor
Pulmonary hyalinizing granuloma
Combined pulmonary fibrosis and emphysema