The pathogenetic mechanisms underlying the disorder are thought to be related to the altered proportion of tau isoforms or to the ability of tau to bind microtubules and to promote microtubule assembly.
Frontotemporal dementia and parkinsonism linked to chromosome 17
Familial encephalopathy with neuroserpin inclusion bodies
Myopathy, X-linked, with excessive autophagy
Limbic-predominant age-related TDP-43 encephalopathy
Variably protease-sensitive prionopathy
Huntington's disease-like syndrome
Spinal muscular atrophy with progressive myoclonic epilepsy
SYNGAP1-related intellectual disability