<unk>  is an abnormality of bones caused by a broad spectrum of disorders. Most commonly these disorders are caused by deficiencies of minerals such as calcium, phosphorus, magnesium or vitamin D leading to dramatic clinical disorders that are commonly reversible once the underlying defect has been treated. These disorders are to be differentiated from a larger group of genetic bone disorders where there is a defect in a specific signaling system or cell type that causes the bone disorder. There may be overlap. For example, genetic or hereditary hypophosphatemia may cause the<unk>  bone disorder osteomalacia. Although there is currently no treatment for the genetic condition, replacement of phosphate often corrects or improves the<unk>  bone disorder. __TOC__
Metabolic bone disease
Oncogenic osteomalacia
Endocrine bone disease
Juvenile osteoporosis
Steroid-induced osteoporosis
Osteopetrosis
Paget's disease of bone
Vitamin D toxicity