Surgical approach for removal is transsphenoidal at the base of the skull. Hormonal suppressive therapy with luteinizing hormone receptor agonists like leuprorelin can be used to treat the seizure component, and are effective in most patients. Surgery is offered if there is failure of medical therapy or rapid growth of lesion, with specific options including stereotactic thermocoagulation, gamma knife radiosurgery, and physical resection by transsphenoidal microsurgery. Surgical response is typically better when the seizure focus has been found by EEG to originate in or near the mass. The specific location of the lesion relative to the pituitary and infundibulum and the amount of hormonal disturbance at presentation can help predict risk of hypopituitarism following surgery.
Tuber cinereum hamartoma
Eruptive vellus hair cyst
Ectodermal dysplasia with corkscrew hairs
Rathke's cleft cyst
Ganglion cyst
Trichofolliculoma
Neuroma cutis
Fibrous hamartoma of infancy