The treatment varies depending on complications but tend to be quite standard, reflecting the treatment of the general population. Management guidelines, divided by systems, including general, developmental, dental, growth and feeding, cardiovascular, audiological, haematological, renal and skeletal, that account for actions to be taken at diagnosis, after diagnosis and if symptomatic, have been published by an American consortium. Specifically, treatment of cardiovascular complications resemble that of the general population and treatment of bleeding diathesis is guided by the specific factor deficiency or platelet aggregation. * Neuropsychological testing is recommended to find strengths and challenges to tailor support needed for school and career. * Educational customization such as an individualized education program plan is sometimes needed for school-aged children. * Speech therapy if speech and articulation issues present * Physical therapy and occupational therapy for gross- and fine-motor delays * Hypotonia and motor difficulties often impact handwriting. Accommodations for lessening handwriting demands will improve performance and save long-term hand function. * Periodic follow up and lifelong monitoring of abnormalities found in any system, especially the cardiovascular system, is recommended. Anesthesia risk Although a few people with<unk>  have been reported to develop malignant hyperthermia, the gene mutation of diseases known to be associated with malignant hyperthermia is different from that of<unk> .
Noonan syndrome
Growth hormone deficiency
Avellis syndrome
Williams syndrome
Muenke syndrome
Christianson syndrome
GRACILE syndrome
Sugarman syndrome