<unk>  does not necessarily need to be treated, and most people with a<unk>  recover without specific medical attention. Although it is unpleasant,<unk>  rarely rises to a dangerous level even if untreated. Damage to the brain generally does not occur until temperatures reach 42 °C (107.6 °F), and it is rare for an untreated<unk>  to exceed 40.6 °C (105 °F). Treating<unk>  in people with sepsis does not affect outcomes. Conservative measures Limited evidence supports sponging or bathing<unk> ish children with tepid water. The use of a fan or air conditioning may somewhat reduce the temperature and increase comfort. If the temperature reaches the extremely high level of hyperpyrexia, aggressive cooling is required (generally produced mechanically via conduction by applying numerous ice packs across most of the body or direct submersion in ice water). In general, people are advised to keep adequately hydrated. Whether increased fluid intake improves symptoms or shortens respiratory illnesses such as the common cold is not known. Medications Medications that lower<unk> s are called antipyretics. The antipyretic ibuprofen is effective in reducing<unk> s in children. It is more effective than acetaminophen (paracetamol) in children. Ibuprofen and acetaminophen may be safely used together in children with<unk> s. The efficacy of acetaminophen by itself in children with<unk> s has been questioned. Ibuprofen is also superior to aspirin in children with<unk> s. Additionally, aspirin is not recommended in children and young adults (those under the age of 16 or 19 depending on the country) due to the risk of Reye's syndrome. Using both paracetamol and ibuprofen at the same time or alternating between the two is more effective at decreasing<unk>  than using only paracetamol or ibuprofen. It is not clear if it increases child comfort. Response or nonresponse to medications does not predict whether or not a child has a serious illness. With respect to the effect of antipyretics on the risk of death in those with infection, studies have found mixed results as of 2019. Animal models have found worsened outcomes with the use of antipyretics in influenza as of 2010 but they have not been studied for this use in humans.
Fever
Hyperthermia
Alertness
Cough
Sedation
Continuous fever
Rash
Nausea