A 10 mg edrophonium chloride syringe and a 2 mg atropine syringe are prepared. Atropine is prepared for immediate use in case cholinergic crisis occurs. After a neurologic examination and recording of vital signs, 2 mg edrophonium is injected intravenously. After waiting 30 seconds and ensuring that no adverse reactions have occurred, the remaining 8 mg of edrophonium is also injected. A patient suffering from myasthenia gravis experiences worsening muscle strength and endurance with repetitive movements, while healthy persons do not feel any difference. The effects of edrophonium lasts around 10 minutes. The edrophonium allows accumulation of acetylcholine (ACh) in the neuromuscular junctions, and makes more ACh available to the muscle receptors, thereby increasing muscle strength in myasthenia gravis. In newborns, a 0.15 mg/kg Neostigmine administered subcutaneously produces a response within 10 minutes. In infants, the drug is administered intravenously at a dose of 0.2 mg/kg. Improvement of diplopia is often used as an evaluation item because in this case, placebo effect can be excluded.
Tensilon test
Stenger test
Goldberg test
Cover test
Rorschach test
Schick test
Dix–Hallpike test
Thomas test