Thioguanine Mercaptopurine Azathioprine The<unk>  drugs are purine antimetabolites widely used in the treatment of acute lymphoblastic leukemia, autoimmune disorders (e.g., Crohn's disease, rheumatoid arthritis), and organ transplant recipients. Metabolism is catalyzed by S-methyltransferase. Litigation over patents covering diagnostic kits to monitor the dosing of these drugs led to a US Supreme Court case, Mayo Collaborative Services v. Prometheus Laboratories, Inc. that dramatically changed the nature of patent law in the United States.
Thiopurine
1-Methylnicotinamide
Boroline
Mercaptopurine
Metadoxine
Pyridoxine
Dimethyl methylphosphonate
Riboflavin