Initial treatment for any type of transfusion reaction, including AHTR, is discontinuation of the transfusion. Fluid replacement and close monitoring of vital signs are important. People with AHTR are managed with supportive care, which may include diuretics, blood pressure support, and treatment of disseminated intravascular coagulation (with fresh frozen plasma, cryoprecipitate, and platelet transfusion). Furosemide is the diuretic of choice in treatment of AHTR with decreased urine output, because it increases the amount of blood that reaches the renal cortex. Mannitol may also be used. Dopamine is used for blood pressure support because it causes vasodilation (dilation of blood vessels) in the kidneys as well as increasing the cardiac output (amount of blood pumped by the heart each minute).
Acute hemolytic transfusion reaction
Delayed hemolytic transfusion reaction
Post-transfusion purpura
Transfusion-dependent anemia
Transfusion associated circulatory overload
Hypotensive transfusion reaction
Allergic transfusion reaction
Atypical hemolytic uremic syndrome