Medical uses<unk>  is classified as an antihypertensive by the World Health Organization and the National Institute of Health. It has been used to reverse pulmonary hypertension caused by protamine (which in turn was administered to reverse the effects of heparin overdose). The reduction in hypertension is not associated with reflex tachycardia. It has been used in cardiac surgery. A 2000 Cochrane Review found that, compared to placebo,<unk>  did not provide significant relief for people suffering from Raynaud's phenomenon attacks in the setting of progressive systemic sclerosis (an autoimmune disorder). While the frequency of the attacks was unaffected by<unk> , there was a reduction in the duration of the individual attacks. However, due to the significant adverse effect burden, the authors concluded that<unk> 's utility for this indication is likely unbeneficial.<unk>  is a selective<unk> A receptor antagonist that was initially developed as an anti-hypertensive medicine. However, now the drug is available as a topical gel formulation for treating wounds, burns, ulcers, and anal fissures. Its action is through the acceleration of epithelialization. Research uses With tritium (3H) radioactively labeled<unk>  is used as a radioligand for serotonin<unk>  receptors, e.g. in receptor binding assays and autoradiography. This radio-labeling has enabled the study of serotonin<unk> A receptor distribution in the human brain. An autoradiography study of the human cerebellum has found an increasing binding of 3H-ketanserin with age (from below 50 femtomol per milligram tissue at around 30 years of age to over 100 above 75 years). The same research team found no significant correlation with age in their homogenate binding study.<unk>  has also been used with carbon (11C) radioactively labeled NNC112 in order to image cortical D1 receptors without contamination by<unk>  receptors. Increasing research into the use of psychedelics as antidepressants has seen<unk>  used to both terminate the hallucinogenic experience, and to disentangle the specific cognitive effects of<unk> A activation.
Ketanserin
Mianserin
Nabilone
Sumatriptan
Naratriptan
Triptan
Blonanserin
Zolmitriptan