Those affected with DIRA have inherited (via autosomal recessive manner) mutations in IL1RN, a gene that encodes a protein known as<unk> <unk><unk><unk> , The cytogenetic location of IL1RN is 2q14.1, while its 2:113,099,364-113,134,015 are the genomic coordinates.
Deficiency of the interleukin-1–receptor antagonist
Leukocyte adhesion molecule deficiency
Terminal complement pathway deficiency
Neutrophil-specific granule deficiency
Acquired C1 esterase inhibitor deficiency
Mendelian susceptibility to mycobacterial disease
CD25 deficiency
Immunodeficiency with hyperimmunoglobulin M