The combination of the syn-configuration of the methoxyimino moiety and the aminothiazole moiety confers extra stability to β-lactamase enzymes produced by many bacteria. The N-methylpyrrolidine moiety increases penetration into Gram-negative bacteria. These factors increase the activity of<unk>  against otherwise resistant organisms including Pseudomonas aeruginosa and Staphylococcus aureus.
Cefepime
Meropenem
Azithromycin
Levofloxacin
Aztreonam
Imipenem
Vancomycin
Telithromycin