<unk>  furoate works only in the digestive tract and is a lumenal amebicide. It is considered second line treatment for infection with amoebas when no symptoms are present but the person is passing cysts, in places where infections are not common. Paromomycin is considered the first line treatment for these cases. For people who are symptomatic, it is used after treatment with ambecides that can penetrate tissue, like metronidazole or tinidazole.<unk>  is considered second-line, while paromomycin is considered first line for this use as well.
Diloxanide
Nitazoxanide
Secnidazole
Benznidazole
Tinidazole
Fexinidazole
Elixir sulfanilamide
Oxytetracycline