A 2006 study followed 223 patients for up to twenty years. Of these, 15 died, with a median age of 65 years. The authors tentatively concluded that this is in line with a previously reported estimate of a shortened life expectancy of 10–15 years (12 in their data). Greater than fifty percent of individuals with<unk>  develop lower limb weakness. Weakness most often begins between the age of 30 and 60. Weakness typically becomes severe enough to necessitate a wheelchair about twenty years following the onset of symptoms.
Spinal and bulbar muscular atrophy
Infantile progressive bulbar palsy
Ataxic cerebral palsy
Madras motor neuron disease
Multiple system atrophy
Spinal muscular atrophy
Spinal muscular atrophy with lower extremity predominance 1
Babinski–Nageotte syndrome