<unk>  has been characterized by prolonged febrile and non-febrile seizures within the first year of a child’s life. This disease progresses to other seizure types like myoclonic and partial seizures, psychomotor delay, and ataxia. It is characterized by cognitive impairment, behavioral disorders, and motor deficits. Behavioral deficits often include hyperactivity and impulsiveness, and in more rare cases, autistic-like behaviors.<unk>  is also associated with sleep disorders including somnolence and insomnia. The seizures experienced by people with<unk>  become worse as the patient ages, as the disease is not very observable when symptoms first appear. This coupled with the range of severity differing between each individual diagnosed and the resistance of these seizures to drugs has made it challenging to develop treatments.<unk>  appears during the first year of life, often beginning around six months of age with frequent febrile seizures (fever-related seizures). Children with<unk>  typically experience a lagged development of language and motor skills, hyperactivity and sleep difficulties, chronic infection, growth and balance issues, and difficulty relating to others. The effects of this disorder do not diminish over time, and children diagnosed with<unk>  require fully committed caretakers with tremendous patience and the ability to closely monitor them. Febrile seizures are divided into two categories known as simple and complex. A febrile seizure would be categorized as complex if it has occurred within 24 hours of another seizure or if it lasts longer than 15 minutes. A febrile seizure lasting less than 15 minutes would be considered simple. Sometimes modest hyperthermic stressors like physical exertion or a hot bath can provoke seizures in affected individuals. However, any seizure uninterrupted after 5 minutes, without a resumption of postictal (more normal; recovery-type; after-seizure) consciousness can lead to potentially fatal status epilepticus.
Dravet syndrome
Stratton Parker syndrome
De Barsy syndrome
Rett syndrome
Shapiro syndrome
Catel–Manzke syndrome
Benedikt syndrome
Huntington's disease-like syndrome