Café au lait spots are usually present at birth, permanent, and may grow in size or increase in number over time. Cafe au lait spots are themselves benign and do not cause any illness or problems. However, they may be associated with syndromes such as Neurofibromatosis Type 1 and McCune-Albright syndrome. The size and shape of the spots can vary in terms of description. In Neurofibromatosis Type 1, the spots tend to be described as ovoid, with smooth borders. In other disorders, the spots can be less ovoid, with jagged borders. In Neurofibromatosis Type 1, the spots tend to resemble the "coast of California," rather than the "coast of Maine," meaning the edges are smoother and more linear.
symptom of Legius syndrome
symptom of Carpal tunnel syndrome
symptom of Motion sickness
symptom of Romano–Ward syndrome
symptom of Avascular necrosis
symptom of Myasthenia gravis
symptom of Dermatomyositis
symptom of Tendinopathy