<unk>  is caused by the obstruction of the tubular space inside the appendix. This initial problem is compounded into a cascade of events that lead to the inflammation of the appendix, the obstruction of the blood vessels supplying it, and infection.  Once these blood vessels are obstructed, appendiceal tissue starts to die and leak out its cellular components.
Appendicitis pathophysiology
Cervicitis pathophysiology
Urethritis pathophysiology
Diverticulitis pathophysiology
Stomatitis pathophysiology
Gonorrhea pathophysiology
Ascariasis pathophysiology
Volvulus pathophysiology