<unk>  is a selective inhibitor of the NMDA receptor. Its effect is specific to receptors composed of the NR1 (glycine-binding NMDA receptor subunit 1; GluN1) and NR2B (glutamate-binding NMDA receptor subunit 2; GluN2B) subunits.
NMDA receptors are multimeric ionotropic glutamate receptors composed of four subunits. NR1 is obligate for functional expression. Other subunits include NR2A, NR2B, and the more recently discovered NR3 subunits.<unk>  selectively blocks NMDA receptors containing the NR2B subunit.
Ifenprodil
Avacopan
Silafluofen
Amlexanox
Magaldrate
Atogepant
Pleconaril
Cloricromen