Antibiotics (aminoglycosides, fluroquinolones, clindamycin, metronidazole, macrolides)
Steroids
Anticonvulsants (phenytoin, barbiturates, lithium)
Psychotropics (haloperidol)
Beta-blockers / calcium-channel blockers
Local anesthetics
Opioids
Anticholinergics (diphenhydramine)
NMJ blocking agents (rocuronium, succinylcholine)
Neuromuscular weakness
Upper motor neuron:
CVA
Hemorrhagic stroke
Multiple sclerosis
Amyotrophic Lateral Sclerosis (ALS) (UMN & LMN)
Lower motor neuron:
Spinal and bulbar muscular atrophy (Kennedy's syndrome)
Spinal cord disease:
Infection (Epidural abscess)
Infarction/ischemia
Trauma (Spinal Cord Syndromes)
Inflammation (Transverse Myelitis)
Acute flaccid myelitis
Degenerative (Spinal muscular atrophy)
Tumor
Peripheral nerve disease:
Guillain-Barre syndrome
Toxins (Ciguatera)
Tick paralysis
Diabetic peripheral neuropathy
NMJ disease:<unk>  crisis
Botulism
Organophosphate toxicity
Lambert-Eaton<unk>  syndrome
Muscle disease:
Rhabdomyolysis
Dermatomyositis
Polymyositis
Alcoholic myopathy
Non-neuromuscular weakness
Can't miss diagnoses:
ACS
Arrhythmia/Syncope
Severe infection/Sepsis
Hypoglycemia
Periodic paralysis (electrolyte disturbance, K,<unk> , Ca)
Hypokalemic periodic paralysis
Thyrotoxic periodic paralysis
Respiratory failure
Emergent Diagnoses:
Symptomatic Anemia
Severe dehydration
Hypothyroidism
Polypharmacy
Malignancy
Other causes of weakness and paralysis
Acute intermittent porphyria (ascending weakness)
Upper motor neuron:
CVA
Hemorrhagic stroke
Multiple sclerosis
Amyotrophic Lateral Sclerosis (ALS) (UMN & LMN)
Lower motor neuron:
Spinal and bulbar muscular atrophy (Kennedy's syndrome)
Spinal cord disease:
Infection (Epidural abscess)
Infarction/ischemia
Trauma (Spinal Cord Syndromes)
Inflammation (Transverse Myelitis)
Acute flaccid myelitis
Degenerative (Spinal muscular atrophy)
Tumor
Peripheral nerve disease:
Guillain-Barre syndrome
Toxins (Ciguatera)
Tick paralysis
Diabetic peripheral neuropathy
NMJ disease:<unk>  crisis
Botulism
Organophosphate toxicity
Lambert-Eaton<unk>  syndrome
Muscle disease:
Rhabdomyolysis
Dermatomyositis
Polymyositis
Alcoholic myopathy
CVA
Hemorrhagic stroke
Multiple sclerosis
Amyotrophic Lateral Sclerosis (ALS) (UMN & LMN)
Spinal and bulbar muscular atrophy (Kennedy's syndrome)
Infection (Epidural abscess)
Infarction/ischemia
Trauma (Spinal Cord Syndromes)
Inflammation (Transverse Myelitis)
Acute flaccid myelitis
Degenerative (Spinal muscular atrophy)
Tumor
Acute flaccid myelitis
Guillain-Barre syndrome
Toxins (Ciguatera)
Tick paralysis
Diabetic peripheral neuropathy<unk>  crisis
Botulism
Organophosphate toxicity
Lambert-Eaton<unk>  syndrome
Rhabdomyolysis
Dermatomyositis
Polymyositis
Alcoholic myopathy
Can't miss diagnoses:
ACS
Arrhythmia/Syncope
Severe infection/Sepsis
Hypoglycemia
Periodic paralysis (electrolyte disturbance, K,<unk> , Ca)
Hypokalemic periodic paralysis
Thyrotoxic periodic paralysis
Respiratory failure
Emergent Diagnoses:
Symptomatic Anemia
Severe dehydration
Hypothyroidism
Polypharmacy
Malignancy
Other causes of weakness and paralysis
Acute intermittent porphyria (ascending weakness)
ACS
Arrhythmia/Syncope
Severe infection/Sepsis
Hypoglycemia
Periodic paralysis (electrolyte disturbance, K,<unk> , Ca)
Hypokalemic periodic paralysis
Thyrotoxic periodic paralysis
Respiratory failure
Hypokalemic periodic paralysis
Thyrotoxic periodic paralysis
Symptomatic Anemia
Severe dehydration
Hypothyroidism
Polypharmacy
Malignancy
Acute intermittent porphyria (ascending weakness)
Myasthenia gravis
Antibiotics 
Polymyositis
Steroids
Lambert-Eaton myasthenic syndrome
Anticonvulsants 
Tick paralysis
Psychotropics 