Neuroimaging usually normal
CSF Studies
Crypto antigen (100% Sn & Sp)
Crypto culture (95%-100% Sn)
India Ink (60-80% Sn)
Opening pressure
Usually elevated; drain CSF until pressure is <20 or 50% of opening presure
Serum
Cryptococcal antigen testing (95% Sn)
Crypto antigen (100% Sn & Sp)
Crypto culture (95%-100% Sn)
India Ink (60-80% Sn)
Usually elevated; drain CSF until pressure is <20 or 50% of opening presure
Cryptococcal antigen testing (95% Sn)
Cryptococcosis
Migraine headache
Histoplasmosis
Tension headache
Toxoplasmosis
Cluster headache
Echinococcosis
Meningitis/encephalitis