Up to 50% of cases will be asymptomatic
Incubation period: 3-6 weeks
Flu like symptoms: Fever, chills, cough, muscle aches, joint pain, chest pain
Other systemic symptoms: Weight loss, night sweats, chills
Pulmonary: most common
Acute or chronic pneumonia
Diffuse pneumonitis, ARDS
Skin:
Verrucous lesion with irregular borders
Microabscess (cold), subcutaneous nodules like erythema nodosum
Ulcers that bleed easily and well-demarcated
Bone: Osteomyelitis, chronic draining sinus, paravertebral abscess
Genitourinary: Prostatitis, Epididymorchitis
CNS: Meningitis, epidural abscess Brain abscess in immunocompromised
Can involve breast, adrenal, thyroid, eye, lymph node, liver, spleen
Acute or chronic pneumonia
Diffuse pneumonitis, ARDS
Verrucous lesion with irregular borders
Microabscess (cold), subcutaneous nodules like erythema nodosum
Ulcers that bleed easily and well-demarcated
Blastomycosis
Pneumonia
Sporotrichosis
Malignancy
Mucormycosis
Tuberculosis
Coccidioidomycosis
Histoplasmosis