Longitudinal lacerations through mucosa and submucosa
75% in proximal stomach, rest in distal esophagus
Due to sudden increase in intrabdominal pressure
Typically in the setting of forceful vomiting or retching
Typically in the setting of forceful vomiting or retching
Mallory-Weiss tear
Peptic ulcer disease 
Esophageal varices
Gastritis/esophagitis
Zenker's diverticulum
Gastric/esophageal varices
Achalasia
Esophageal candidiasis