ID consult
Mild or moderate infections: Itraconazole (200mg TID x 3 days then once or twice daily x 6-12 months)
Alternative: Fluconazole or ketoconazole (400-800mg/day)
Azoles embryotoxic and teratogenic, avoid in pregnancy
Severe infection: Amphotericin B (Lipid 3-5mg/kg IV daily or deoxycholate 0.7-1mg/kg IV daily)
All immunocompromised patient should receive amphotericin B
Lipid for all patients, except children
If CNS involvement, lipid for all patients
Alternative: Fluconazole or ketoconazole (400-800mg/day)
Azoles embryotoxic and teratogenic, avoid in pregnancy
All immunocompromised patient should receive amphotericin B
Lipid for all patients, except children
If CNS involvement, lipid for all patients
Blastomycosis
Pneumonia
Sporotrichosis
Malignancy
Mucormycosis
Tuberculosis
Coccidioidomycosis
Histoplasmosis