Can originate in lymphatic system or any organ in the body
Occurs in children >5 years old
Immunosuppression (e.g. HIV, crohn's, chemotherapy) is a risk factor
Non-Hodgkin's lymphoma
Hodgkin's lymphoma
Chronic lymphocytic leukemia
Acute lymphocytic leukemia
Mononucleosis
Multiple myeloma
Toxoplasmosis
Leukemoid Reaction