Autoimmune collagen vascular disease, aka Systemic<unk> erosis
Inappropriate and excessive accumulation of collagen and matrix in various tissues
Widespread vascular lesions
Endothelial dysfunction
Vascular spasm
Vascular wall thickening
Narrowed lumen
Two types:
Diffuse Systemic<unk> erosis: skin changes, which can progress to internal organ involvement
Limited Cutaneous Systemic<unk> erosis, aka "CREST Syndrome"
Endothelial dysfunction
Vascular spasm
Vascular wall thickening
Narrowed lumen
Diffuse Systemic<unk> erosis: skin changes, which can progress to internal organ involvement
Limited Cutaneous Systemic<unk> erosis, aka "CREST Syndrome"
Scleroderma
Systemic Lupus Erythematosus
Dermatomyositis
Sjögren syndrome
Vitiligo
Acute arterial ischemia
Brash syndrome
Atheroembolism 