Used (alone or with beta-lactam) to treat serious infections due to gram-negative bacilli, e.g.:
Ill patient with pyelonephritis
Meningitis (due to pseudomonas, acinetobacter)
Peritoneal dialysis-associated peritonitis
Bacterial endocarditis
Used +/- beta-lactam
Nephro and oto toxic. Risk of neuromuscular blockade.
Can precipitate crisis in patients with myasthenia gravis
Include gentamicin and tobramycin
Ill patient with pyelonephritis
Meningitis (due to pseudomonas, acinetobacter)
Peritoneal dialysis-associated peritonitis
Bacterial endocarditis
Aminoglycosides
Tetracyclines
Beta-lactams
Fluoroquinolones
Cephalosporins
Penicillins
Carbapenems
Arthropod and parasitic antibiotics