Allergy to class/drug
Caution:
Concurrent CNS depressant use
Alcohol use
Pts < 25 yo
Elderly
Pregnancy 3rd trimester
Hepatic impairment
Poor CYP2D6 metabolizer
Bleeding risk
QT prolongation
CHF
Hypomania or mania history
Avoid abrupt withdrawal
Concurrent CNS depressant use
Alcohol use
Pts < 25 yo
Elderly
Pregnancy 3rd trimester
Hepatic impairment
Poor CYP2D6 metabolizer
Bleeding risk
QT prolongation
CHF
Hypomania or mania history
Fluoxetine
Duloxetine
Bupropion
Venlafaxine
Methylphenidate
Nortriptyline
Amitriptyline
Naltrexone