The diagnosis of<unk><unk>  is made when all four of the WHO<unk>  are met. The diagnostic<unk>  may include: sustained elevation of platelet counts > 450,000,000 × 10³/L, bone marrow biopsy specimen showing proliferation, mainly of the megakaryocytic lineage with increased numbers of enlarged, mature megakaryocytes and no significant increase or left-shift of neutrophil granulopoiesis or erythropoiesis, not meeting WHO<unk>  for polycythemia vera, PMF, CML, MDS, or other myeloid neoplasm, and demonstration of JAK2 617VF or other clonal marker, or in the absence of a clonal marker, no evidence for reactive<unk> .
Essential thrombocytosis diagnostic criteria
Glanzmann's thrombasthenia patient information
Glanzmann's thrombasthenia physical examination
Glanzmann's thrombasthenia laboratory findings
Polycythemia vera diagnostic criteria
Essential thrombocytosis physical examination
Immune Thrombocytopenia epidemiology and demographics
Thrombotic thrombocytopenic purpura physical examination