A<unk>  (sometimes known as an orphan disease) has such a low prevalence in a population that a doctor in a busy general practice would not expect to see more than one case a year.<unk> s, including those of genetic origin, are life-threatening or chronically debilitating diseases which are of such low prevalence that special combined efforts are needed to address them.
Rare disease
Minimal change disease risk factors
Chronic renal failure causes
Osteoporosis causes
Congestive heart failure pathophysiology
Coronary heart disease causes
Chronic renal failure pathophysiology
Spinal muscular atrophy risk factor