<unk>  is a form of edema due to intoxication with Argemone mexicana (Mexican prickly poppy).
In Northern India,<unk>  occurs as  a food adulterant disease where use of mustard oil as cooking medium is common. When mustard oil is adulterated deliberately (as in most cases) or accidental contamination with argemone oil, proteinuria (specifically loss of albumin) occurs, with a resultant edema as would occur in nephrotic syndrome. Other symptoms are bilateral pitting edema of extremities headache, nausea, loose bowels, erythema and breathlessness. In severe cases fatalities are reported due to congestive heart failure.The toxic effects of argemone oil have been attributed to the presence of benzophenanthridine alkaloids, sanguinarine and dihydrosanguinarine. It has been reported that the sanguinarine alkaloid content in argemone oil varies from 0.44% to 0.50%.
Besides India, widespread<unk> s have been reported from Mauritius,Fiji Islands, Northwest Cape districts of South Africa, Madagascar and also from Nepal. Apart from South African study where the<unk>  occurred through contamination in wheat flour, all the<unk> s occurred through the consumption of mustard oil contaminated with argemone oil.
Epidemic dropsy
Relapsing fever
Blackwater fever
Rat-bite fever
Argentine hemorrhagic fever
Lábrea fever
Puerperal fever
Viral hemorrhagic fever