<unk> <unk>  syndrome is a medical condition, typically starting in young children, in which high<unk>  occurs<unk> ally at intervals of about 3-5 weeks, frequently accompanied by<unk>  ulcers,<unk>  and/or<unk> . The syndrome was described in 1987 and named two years later.
Periodic fever, aphthous stomatitis, pharyngitis and adenitis
Fever and rash in children
Pyogenic sterile arthritis, pyoderma gangrenosum, acne
Chronic mucocutaneous candidiasis
Asthma and gastroesophageal reflux
Congestive heart failure and obstructive sleep apnea
Multifocal choroiditis and panuveitis
Cardiac disease in pregnancy and pulmonary hypertension