<unk>  <unk> A) is a human genetic disease. It follows a sex-linked, dominant inheritance pattern, but is approximately equally prevalent in both males and females. It affects a gene which codes for a critical enzyme complex, the<unk><unk>  complex (PDC) which links the metabolic pathways of glycolysis and the citric acid cycle by transforming<unk>  into Acetyl CoA
The<unk><unk>  complex facilitates oxidative decarboxylation, the chemical reaction between glycolysis and the citric acid cycle.
Pyruvate dehydrogenase deficiency
Alpha-ketoglutarate dehydrogenase deficiency
Pyruvate kinase deficiency
ALA dehydratase deficiency
Ornithine transcarbamylase deficiency
Aldolase A deficiency
Isobutyryl-coenzyme A dehydrogenase deficiency
Very long-chain acyl-coenzyme A dehydrogenase deficiency