<unk>  is one of two types of bone formation and is the process responsible for the development of flat bones, especially those found in the skull and clavicles. Unlike endochondral<unk> , cartilage is not involved or present in this process.
The first step in the process is the formation of bone spicules which eventually fuse with each other and become trabeculae. The periosteum is formed and bone growth continues at the surface of trabeculae. Much like spicules, the increasing growth of trabeculae result in interconnection and this network is called woven bone. Eventually, woven bone is replaced by lamellar bone.
Process Overview
Mesenchyme cell in the membrane become osteochondral progenitor cell
osteochondral progenitor cell specialized to become osteoblast
Osteoblast produce bone matrix and surrounded collagen fiber and become osteocyte
As the result process trabeculae will develop
Osteoblast will trap trabeculae to produce bone
Trabeculae will join together to produce spongy cell
Cells in the spongy cell will specialize to produce red bone marrow
Cells surrounding the developing bone will produce periosteum
Osteoblasts from the Periosteum on the bone matrix will produce compact bone
Intramembranous ossification
Heterotopic ossification
Metastatic calcification
Periosteal reaction
Exostosis
Reticular formation
Pseudolesion
Repetitive strain injury