{TAIL ~ Such dosages} will be administered to a subject in need of {HEAD ~ treatment} from once to about three times each day, or more often as needed to effectively treat the problem 
{ TAIL ~ Such dosages } will be administered to a subject in need of { HEAD ~ treatment } from once to about three times each day , or more often as needed to effectively treat the problem
TAIL TAIL TAIL TAIL TAIL TAIL OTH OTH OTH OTH OTH OTH OTH OTH OTH HEAD HEAD HEAD HEAD HEAD OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH