The mixing reaction of {HEAD ~ the animal plasma}, FXII activator and tested substance is preferably carried out at 0° C. to 4° C. so that the intrinsic inhibitor hardly acts and, in addition, {TAIL ~ the progress} of the reaction can be easily controlled 
The mixing reaction of { HEAD ~ the animal plasma } , FXII activator and tested substance is preferably carried out at 0 ° C. to 4 ° C. so that the intrinsic inhibitor hardly acts and , in addition , { TAIL ~ the progress } of the reaction can be easily controlled
OTH OTH OTH OTH HEAD HEAD HEAD HEAD HEAD HEAD HEAD OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH TAIL TAIL TAIL TAIL TAIL TAIL OTH OTH OTH OTH OTH OTH OTH