An object of the invention is to provide a method for the treatment and prevention of bacterial infection caused by {TAIL ~ Enterobacteriaceae family} in central nervous system and peripheral blood circulation in a mammal, which comprises administering to said mammal an effective amount of an outer membrane protein A from {HEAD ~ Enterobacteriaceae family} 
An object of the invention is to provide a method for the treatment and prevention of bacterial infection caused by { TAIL ~ Enterobacteriaceae family } in central nervous system and peripheral blood circulation in a mammal , which comprises administering to said mammal an effective amount of an outer membrane protein A from { HEAD ~ Enterobacteriaceae family }
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