Methods to activate the carboxylic acid include reacting said acid with {HEAD ~ one or more molar equivalents} of {TAIL ~ oxalyl chloride} or thionyl chloride to afford the carboxylic acid chloride in a suitable solvent such as dichloromethane, chloroform or diethyl ether 
Methods to activate the carboxylic acid include reacting said acid with { HEAD ~ one or more molar equivalents } of { TAIL ~ oxalyl chloride } or thionyl chloride to afford the carboxylic acid chloride in a suitable solvent such as dichloromethane , chloroform or diethyl ether
OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH HEAD HEAD HEAD HEAD HEAD HEAD HEAD HEAD HEAD REL TAIL TAIL TAIL TAIL TAIL TAIL OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH