A pharmaceutical composition comprising at least one pharmaceutically acceptable carrier or adjuvant and an effective TNF α release inhibiting amount of a substituted 2,4 imidazolidinedione compound corresponding to {TAIL ~ the formula} {HEAD ~ I} ##STR24## wherein R1 represents C1 6 alkyl or C3 6 cycloalkyl 
A pharmaceutical composition comprising at least one pharmaceutically acceptable carrier or adjuvant and an effective TNF α release inhibiting amount of a substituted 2,4 imidazolidinedione compound corresponding to { TAIL ~ the formula } { HEAD ~ I } # # STR24 # # wherein R1 represents C1 6 alkyl or C3 6 cycloalkyl
OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH TAIL TAIL TAIL TAIL TAIL TAIL HEAD HEAD HEAD HEAD HEAD OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH