The invention comprises a low temperature method for the in situ derivatization and coupling of {HEAD ~ thermally and hydrolytically labile organic compounds} such as {TAIL ~ spectinomycin} to immunogenic carrier substances 
The invention comprises a low temperature method for the in situ derivatization and coupling of { HEAD ~ thermally and hydrolytically labile organic compounds } such as { TAIL ~ spectinomycin } to immunogenic carrier substances
OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH HEAD HEAD HEAD HEAD HEAD HEAD HEAD HEAD HEAD HEAD REL REL TAIL TAIL TAIL TAIL TAIL OTH OTH OTH OTH