{HEAD ~ IRS1 or IRS2 functional activity} also integrate {TAIL ~ signals} emanating from proinflammatory cytokines, including TNFα, IL6, IL1β and related factors 
{ HEAD ~ IRS1 or IRS2 functional activity } also integrate { TAIL ~ signals } emanating from proinflammatory cytokines , including TNFα , IL6 , IL1β and related factors
HEAD HEAD HEAD HEAD HEAD HEAD HEAD HEAD HEAD OTH REL TAIL TAIL TAIL TAIL TAIL OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH