R is phenyl, W substituted phenyl, naphthyl, W substituted naphthyl, benzodioxolyl, heteroaryl, {HEAD ~ W} substituted {TAIL ~ heteroaryl}, benzofused heteroaryl and W substituted benzofused heteroaryl, wherein heteroaryl is selected from the group consisting of pyrrolyl, pyridinyl, pyrimidinyl, pyrazinyl, triazinyl, imidazolyl, thiazolyl, pyrazolyl, thienyl, oxazolyl and furanyl, and for nitrogen containing heteroaryls, the N oxides thereof 
R is phenyl , W substituted phenyl , naphthyl , W substituted naphthyl , benzodioxolyl , heteroaryl , { HEAD ~ W } substituted { TAIL ~ heteroaryl } , benzofused heteroaryl and W substituted benzofused heteroaryl , wherein heteroaryl is selected from the group consisting of pyrrolyl , pyridinyl , pyrimidinyl , pyrazinyl , triazinyl , imidazolyl , thiazolyl , pyrazolyl , thienyl , oxazolyl and furanyl , and for nitrogen containing heteroaryls , the N oxides thereof
OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH HEAD HEAD HEAD HEAD HEAD REL TAIL TAIL TAIL TAIL TAIL OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH