A method for evaluating the prognostic value in a patient in the resected stage I lung adenocarcinoma comprising the steps of collecting a tissue sample from the patient, determining the level of TOPK expressed in the tissue sample, wherein {HEAD ~ the prognostic value} of {TAIL ~ the patient} is worst if the overexpression of TOPK in the patients tissue sample is found 
A method for evaluating the prognostic value in a patient in the resected stage I lung adenocarcinoma comprising the steps of collecting a tissue sample from the patient , determining the level of TOPK expressed in the tissue sample , wherein { HEAD ~ the prognostic value } of { TAIL ~ the patient } is worst if the overexpression of TOPK in the patients tissue sample is found
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