The resulting scaffold structures are characterized by their rigidity, stereochemical and functional {HEAD ~ group complexity}, high density and diversity of functionality radially arrayed from which to generate highly diversified libraries, and by the minimal need to employ protecting groups during {TAIL ~ the synthesis} of the scaffold structures and combinatorial libraries 
The resulting scaffold structures are characterized by their rigidity , stereochemical and functional { HEAD ~ group complexity } , high density and diversity of functionality radially arrayed from which to generate highly diversified libraries , and by the minimal need to employ protecting groups during { TAIL ~ the synthesis } of the scaffold structures and combinatorial libraries
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