{TAIL ~ Breeding} of the human heavy chain transgenic animals with transgenic non human animals containing a human immunoglobulin light chain transgene produces {HEAD ~ transgenic non human animals} containing a human heavy chain transgene of the invention and a human light chain transgene 
{ TAIL ~ Breeding } of the human heavy chain transgenic animals with transgenic non human animals containing a human immunoglobulin light chain transgene produces { HEAD ~ transgenic non human animals } containing a human heavy chain transgene of the invention and a human light chain transgene
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