Feedback control alone cannot avoid large fluctuations in BIS values when significant surgical stimulation is imposed, as a result of time delays in {HEAD ~ a patients response} to {TAIL ~ drug infusion} 
Feedback control alone can not avoid large fluctuations in BIS values when significant surgical stimulation is imposed , as a result of time delays in { HEAD ~ a patients response } to { TAIL ~ drug infusion }
OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH HEAD HEAD HEAD HEAD HEAD HEAD HEAD REL TAIL TAIL TAIL TAIL TAIL TAIL