{HEAD ~ Optimal dosages} to be administered may be readily determined by those skilled in the art, and will vary with the particular compound used, {TAIL ~ the mode} of administration, the strength of the preparation, the mode of administration, and the advancement of the disease condition 
{ HEAD ~ Optimal dosages } to be administered may be readily determined by those skilled in the art , and will vary with the particular compound used , { TAIL ~ the mode } of administration , the strength of the preparation , the mode of administration , and the advancement of the disease condition
HEAD HEAD HEAD HEAD HEAD HEAD OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH REL REL OTH OTH OTH OTH OTH TAIL TAIL TAIL TAIL TAIL TAIL OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH