IRS1 and IRS2 are part of the insulin or insulin like growth factor signaling pathways, but also mediate some signals through other growth factors and {HEAD ~ cytokines}, including IFNγ, IL2, IL4, IL7, IL9, IL13 or IL15, {TAIL ~ growth hormone}, prolactin, or leptin 
IRS1 and IRS2 are part of the insulin or insulin like growth factor signaling pathways , but also mediate some signals through other growth factors and { HEAD ~ cytokines } , including IFNγ , IL2 , IL4 , IL7 , IL9 , IL13 or IL15 , { TAIL ~ growth hormone } , prolactin , or leptin
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