Th preparation of a double stranded polydeoxy ribonucleotide having cohesive termini each comprising one strand of a double strand restriction endonuclease recognition site and, between the termini, a structural gene coating for the expression of recombinant growth hormone releasing factor, at least a majority of the codons and the coding strand of {HEAD ~ said gene} being codons preferred for the expression of microbial genomes; a method of producing such DNA a recombinant microbial cloning vehicle comprising such DNA and {TAIL ~ the novel methods} of producing said peptide are described 
Th preparation of a double stranded polydeoxy ribonucleotide having cohesive termini each comprising one strand of a double strand restriction endonuclease recognition site and , between the termini , a structural gene coating for the expression of recombinant growth hormone releasing factor , at least a majority of the codons and the coding strand of { HEAD ~ said gene } being codons preferred for the expression of microbial genomes ; a method of producing such DNA a recombinant microbial cloning vehicle comprising such DNA and { TAIL ~ the novel methods } of producing said peptide are described
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