In another embodiment, the invention provides a substantially pure polypeptide characterized by having an amino acid sequence derived from {TAIL ~ carboxy terminal amino acids} of {HEAD ~ a hedgehog protein} and having at its amino terminus, a G↓CF cleavage site specifically recognized by a proteolytic activity of the carboxy terminal fragment of the native hedgehog polypeptide 
In another embodiment , the invention provides a substantially pure polypeptide characterized by having an amino acid sequence derived from { TAIL ~ carboxy terminal amino acids } of { HEAD ~ a hedgehog protein } and having at its amino terminus , a G↓CF cleavage site specifically recognized by a proteolytic activity of the carboxy terminal fragment of the native hedgehog polypeptide
OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH TAIL TAIL TAIL TAIL TAIL TAIL TAIL TAIL OTH HEAD HEAD HEAD HEAD HEAD HEAD HEAD OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH