Therefore, there is a need remaining to provide a method of demethylating 14 OH substituted alkaloid derivatives, and in particular, oxycodone and oxymorphone without {HEAD ~ the need} of protecting/deprotecting {TAIL ~ the 14 OH group} 
Therefore , there is a need remaining to provide a method of demethylating 14 OH substituted alkaloid derivatives , and in particular , oxycodone and oxymorphone without { HEAD ~ the need } of protecting / deprotecting { TAIL ~ the 14 OH group }
OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH HEAD HEAD HEAD HEAD HEAD HEAD REL REL OTH OTH TAIL TAIL TAIL TAIL TAIL TAIL TAIL TAIL