A method for {TAIL ~ long term management} of diabetes by avoiding the problems associated with tight control of blood glucose concentrations, i.e., hypoglycemia tolerance and seizures, while simultaneously avoiding the problems associated with {HEAD ~ conventional moderate control} of blood glucose concentrations, i.e., pathological complications associated with hyperglycemia, such as nephropathy, retinopathy, etc 
A method for { TAIL ~ long term management } of diabetes by avoiding the problems associated with tight control of blood glucose concentrations , i.e. , hypoglycemia tolerance and seizures , while simultaneously avoiding the problems associated with { HEAD ~ conventional moderate control } of blood glucose concentrations , i.e. , pathological complications associated with hyperglycemia , such as nephropathy , retinopathy , etc
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