As a result of earnest investigation of the structure of solid reagent in consideration of such circumstances, the present inventors have found that the above problem can be solved by {HEAD ~ the provision} of {TAIL ~ a clearance} between the reagent layer and the support so that the reagent layer is brought in contact with air from the support side 
As a result of earnest investigation of the structure of solid reagent in consideration of such circumstances , the present inventors have found that the above problem can be solved by { HEAD ~ the provision } of { TAIL ~ a clearance } between the reagent layer and the support so that the reagent layer is brought in contact with air from the support side
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