b) causing the small molecule to come into contact with IRS2 or {TAIL ~ a complex comprising IRS2} and {HEAD ~ other cellular proteins} in the cell; and 
b ) causing the small molecule to come into contact with IRS2 or { TAIL ~ a complex comprising IRS2 } and { HEAD ~ other cellular proteins } in the cell ; and
OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH TAIL TAIL TAIL TAIL TAIL TAIL TAIL TAIL OTH HEAD HEAD HEAD HEAD HEAD HEAD HEAD OTH OTH OTH OTH OTH