In a further embodiments, {HEAD ~ the filtered clarified lysate} is further purified by {TAIL ~ ion exchange chromatography} to remove residual impurities including cellular proteins, chromosomal DNA, RNA and endotoxins 
In a further embodiments , { HEAD ~ the filtered clarified lysate } is further purified by { TAIL ~ ion exchange chromatography } to remove residual impurities including cellular proteins , chromosomal DNA , RNA and endotoxins
OTH OTH OTH OTH OTH HEAD HEAD HEAD HEAD HEAD HEAD HEAD HEAD REL REL REL REL TAIL TAIL TAIL TAIL TAIL TAIL TAIL OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH