IRS1 and {TAIL ~ IRS2} are {HEAD ~ part} of the insulin or insulin like growth factor signaling pathways, but also mediate some signals through other growth factors and cytokines, including IFNγ, IL2, IL4, IL7, IL9, IL13 or IL15, growth hormone, prolactin, or leptin 
IRS1 and { TAIL ~ IRS2 } are { HEAD ~ part } of the insulin or insulin like growth factor signaling pathways , but also mediate some signals through other growth factors and cytokines , including IFNγ , IL2 , IL4 , IL7 , IL9 , IL13 or IL15 , growth hormone , prolactin , or leptin
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