The present invention relates to novel compounds that are {HEAD ~ inhibitors} of {TAIL ~ wild type} and mutant dihydrofolate reductase of Plasmodium falciparum, which are useful for the treatment of malaria 
of
The present invention relates to novel compounds that are { HEAD ~ inhibitors } of { TAIL ~ wild type } and mutant dihydrofolate reductase of Plasmodium falciparum , which are useful for the treatment of malaria
OTH OTH OTH OTH OTH OTH OTH OTH OTH HEAD HEAD HEAD HEAD HEAD REL TAIL TAIL TAIL TAIL TAIL TAIL OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH