{TAIL ~ The cell supernatant} or the solution obtained after centrifugation of {HEAD ~ the mixture} obtained on breaking the cells, which contains proteins, nucleic acids and other cell constituents, is enriched in proteins, including the polypeptides of the invention, in a manner which is known per se 
{ TAIL ~ The cell supernatant } or the solution obtained after centrifugation of { HEAD ~ the mixture } obtained on breaking the cells , which contains proteins , nucleic acids and other cell constituents , is enriched in proteins , including the polypeptides of the invention , in a manner which is known per se
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