The present invention concerns the discovery that proteins encoded by a family of vertebrate genes, termed here hedgehog related genes, comprise {HEAD ~ morphogenic signals} produced by embryonic patterning centers, and are involved in the formation of ordered spatial arrangements of {TAIL ~ differentiated tissues} in vertebrates 
The present invention concerns the discovery that proteins encoded by a family of vertebrate genes , termed here hedgehog related genes , comprise { HEAD ~ morphogenic signals } produced by embryonic patterning centers , and are involved in the formation of ordered spatial arrangements of { TAIL ~ differentiated tissues } in vertebrates
OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH HEAD HEAD HEAD HEAD HEAD HEAD OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH TAIL TAIL TAIL TAIL TAIL TAIL OTH OTH