The methods and {HEAD ~ formulations} comprise modified release elements, providing for drug delivery to {TAIL ~ the affected or desired area} 
The methods and { HEAD ~ formulations } comprise modified release elements , providing for drug delivery to { TAIL ~ the affected or desired area }
OTH OTH OTH HEAD HEAD HEAD HEAD HEAD OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH TAIL TAIL TAIL TAIL TAIL TAIL TAIL TAIL TAIL