A compound 1, or a stereoisomer or tautomer thereof, or {HEAD ~ a pharmaceutically acceptable salt} of {TAIL ~ said compound}, said stereoisomer, or said tautomer, wherein 
of
A compound 1 , or a stereoisomer or tautomer thereof , or { HEAD ~ a pharmaceutically acceptable salt } of { TAIL ~ said compound } , said stereoisomer , or said tautomer , wherein
OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH HEAD HEAD HEAD HEAD HEAD HEAD HEAD HEAD REL TAIL TAIL TAIL TAIL TAIL TAIL OTH OTH OTH OTH OTH OTH OTH OTH OTH