In an embodiment, {HEAD ~ the niacin analog} has {TAIL ~ an EC50} for β arrestin mediated GPR109A function which is at least 10 times greater than the EC50 of niacin for β arrestin mediated GPR109A function 
has
In an embodiment , { HEAD ~ the niacin analog } has { TAIL ~ an EC50 } for β arrestin mediated GPR109A function which is at least 10 times greater than the EC50 of niacin for β arrestin mediated GPR109A function
OTH OTH OTH OTH HEAD HEAD HEAD HEAD HEAD HEAD HEAD REL TAIL TAIL TAIL TAIL TAIL TAIL OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH