Feedback control alone cannot avoid large fluctuations in BIS values when significant surgical stimulation is imposed, as {TAIL ~ a result} of time delays in a patients response to {HEAD ~ drug infusion} 
Feedback control alone can not avoid large fluctuations in BIS values when significant surgical stimulation is imposed , as { TAIL ~ a result } of time delays in a patients response to { HEAD ~ drug infusion }
OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH TAIL TAIL TAIL TAIL TAIL TAIL OTH OTH OTH OTH OTH OTH OTH OTH HEAD HEAD HEAD HEAD HEAD HEAD