By upregulating {HEAD ~ the levels} or functional activity of IRS2, insulin is used more efficiently by the body to control {TAIL ~ nutrient levels} 
By upregulating { HEAD ~ the levels } or functional activity of IRS2 , insulin is used more efficiently by the body to control { TAIL ~ nutrient levels }
OTH OTH HEAD HEAD HEAD HEAD HEAD HEAD OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH TAIL TAIL TAIL TAIL TAIL TAIL