{HEAD ~ The invention} comprises {TAIL ~ a low temperature method} for the in situ derivatization and coupling of thermally and hydrolytically labile organic compounds such as spectinomycin to immunogenic carrier substances 
comprises
{ HEAD ~ The invention } comprises { TAIL ~ a low temperature method } for the in situ derivatization and coupling of thermally and hydrolytically labile organic compounds such as spectinomycin to immunogenic carrier substances
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