Of course, the high boiling solvent may be included initially in {HEAD ~ the charge} of {TAIL ~ reactants} which are used to form the orthoester, i.e., the iminopropionate and alkanol, and thus be ready for the next stage 
of
Of course , the high boiling solvent may be included initially in { HEAD ~ the charge } of { TAIL ~ reactants } which are used to form the orthoester , i.e. , the iminopropionate and alkanol , and thus be ready for the next stage
OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH HEAD HEAD HEAD HEAD HEAD HEAD REL TAIL TAIL TAIL TAIL TAIL OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH