Provided are 4 quinolone derivatives effective in inhibiting or eliminating the viability of at least one of the stages in the life cycle of {HEAD ~ the malarial parasite}, and to show a reduced propensity to induce resistance to {TAIL ~ the compound} by the target parasite 
Provided are 4 quinolone derivatives effective in inhibiting or eliminating the viability of at least one of the stages in the life cycle of { HEAD ~ the malarial parasite } , and to show a reduced propensity to induce resistance to { TAIL ~ the compound } by the target parasite
OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH HEAD HEAD HEAD HEAD HEAD HEAD HEAD OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH TAIL TAIL TAIL TAIL TAIL TAIL OTH OTH OTH OTH