{HEAD ~ The variant} 1, further comprising {TAIL ~ a mutation} selected from the group consisting of: 
comprising
{ HEAD ~ The variant } 1 , further comprising { TAIL ~ a mutation } selected from the group consisting of :
HEAD HEAD HEAD HEAD HEAD HEAD OTH OTH OTH REL TAIL TAIL TAIL TAIL TAIL TAIL OTH OTH OTH OTH OTH OTH OTH