Therapeutic efficacy and toxicity may be determined by {HEAD ~ standard pharmaceutical procedures} in cell cultures or {TAIL ~ experimental animals}, e.g., ED50 and LD50  
in
Therapeutic efficacy and toxicity may be determined by { HEAD ~ standard pharmaceutical procedures } in cell cultures or { TAIL ~ experimental animals } , e.g. , ED50 and LD50
OTH OTH OTH OTH OTH OTH OTH OTH HEAD HEAD HEAD HEAD HEAD HEAD HEAD REL OTH OTH OTH TAIL TAIL TAIL TAIL TAIL TAIL OTH OTH OTH OTH OTH OTH OTH