As an agent to boost immunoresponsiveness among {HEAD ~ individuals} having an acquired loss of {TAIL ~ B cell function} 
As an agent to boost immunoresponsiveness among { HEAD ~ individuals } having an acquired loss of { TAIL ~ B cell function }
OTH OTH OTH OTH OTH OTH OTH HEAD HEAD HEAD HEAD HEAD OTH OTH OTH OTH OTH TAIL TAIL TAIL TAIL TAIL TAIL TAIL