While it has {HEAD ~ an inhibitory effect} on {TAIL ~ AR} in hormone sensitive prostate cancer, it fails to suppress AR when cancer becomes hormone refractory 
on
While it has { HEAD ~ an inhibitory effect } on { TAIL ~ AR } in hormone sensitive prostate cancer , it fails to suppress AR when cancer becomes hormone refractory
OTH OTH OTH HEAD HEAD HEAD HEAD HEAD HEAD HEAD REL TAIL TAIL TAIL TAIL TAIL OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH