In {HEAD ~ other examples} of the invention, the shRNA is {TAIL ~ shTOPK} 3 having a sequence as set forth in SEQ ID NO:3 or shTOPK 4 having a sequence as set forth in SEQ ID NO:4 
In { HEAD ~ other examples } of the invention , the shRNA is { TAIL ~ shTOPK } 3 having a sequence as set forth in SEQ ID NO:3 or shTOPK 4 having a sequence as set forth in SEQ ID NO:4
OTH HEAD HEAD HEAD HEAD HEAD HEAD OTH OTH OTH OTH OTH OTH OTH TAIL TAIL TAIL TAIL TAIL OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH