{HEAD ~ The method} 1, wherein said tropic acid or topically effective salt thereof is applied periodically for a period of {TAIL ~ time} sufficient to achieve at least a clinically discernable reduction of said wrinkle 
{ HEAD ~ The method } 1 , wherein said tropic acid or topically effective salt thereof is applied periodically for a period of { TAIL ~ time } sufficient to achieve at least a clinically discernable reduction of said wrinkle
HEAD HEAD HEAD HEAD HEAD HEAD OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH TAIL TAIL TAIL TAIL TAIL OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH