This invention is directed to {HEAD ~ a general method} for the chronic treatment, potential cure, or prevention of various metabolic and related diseases in people, including diabetes, by modulating IRS2 activity in cells and tissues in {TAIL ~ the body} 
This invention is directed to { HEAD ~ a general method } for the chronic treatment , potential cure , or prevention of various metabolic and related diseases in people , including diabetes , by modulating IRS2 activity in cells and tissues in { TAIL ~ the body }
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