The method 1, wherein said tropic acid or {HEAD ~ topically effective salt} thereof is applied periodically for a period of time sufficient to achieve at least a clinically discernable reduction of {TAIL ~ said wrinkle} 
The method 1 , wherein said tropic acid or { HEAD ~ topically effective salt } thereof is applied periodically for a period of time sufficient to achieve at least a clinically discernable reduction of { TAIL ~ said wrinkle }
OTH OTH OTH OTH OTH OTH OTH OTH OTH HEAD HEAD HEAD HEAD HEAD HEAD HEAD OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH TAIL TAIL TAIL TAIL TAIL TAIL