In order to determine precise T cell epitopes by, for example, fine mapping techniques, a peptide having Der p VII or Der f VII T cell stimulating activity and thus comprising {HEAD ~ at least one T cell epitope} as determined by {TAIL ~ T cell biology techniques} is modified by addition or deletion of amino acid residues at either the amino or carboxy terminus of the peptide and tested to determine a change in T cell reactivity to the modified peptide 
as determined by
In order to determine precise T cell epitopes by , for example , fine mapping techniques , a peptide having Der p VII or Der f VII T cell stimulating activity and thus comprising { HEAD ~ at least one T cell epitope } as determined by { TAIL ~ T cell biology techniques } is modified by addition or deletion of amino acid residues at either the amino or carboxy terminus of the peptide and tested to determine a change in T cell reactivity to the modified peptide
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