{HEAD ~ The present invention} relates to antimalarial compounds or antifolates for the treatment and prophylaxis of malaria and {TAIL ~ methods} of making and using the compounds 
relates to
{ HEAD ~ The present invention } relates to antimalarial compounds or antifolates for the treatment and prophylaxis of malaria and { TAIL ~ methods } of making and using the compounds
HEAD HEAD HEAD HEAD HEAD HEAD HEAD REL REL OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH TAIL TAIL TAIL TAIL TAIL OTH OTH OTH OTH OTH OTH