In some aspects, provided is {HEAD ~ a composition} for administration to an open wound in a subject, comprising a carrier, an active agent and {TAIL ~ a wound} targeting moiety, wherein the wound targeting moiety facilitates local delivery of the active agent to wounded tissue by selectively binding to an exposed protein, peptide motif or epitope, wherein the exposed protein, peptide motif or epitope is exposed upon wounding of the subject 
comprising
In some aspects , provided is { HEAD ~ a composition } for administration to an open wound in a subject , comprising a carrier , an active agent and { TAIL ~ a wound } targeting moiety , wherein the wound targeting moiety facilitates local delivery of the active agent to wounded tissue by selectively binding to an exposed protein , peptide motif or epitope , wherein the exposed protein , peptide motif or epitope is exposed upon wounding of the subject
OTH OTH OTH OTH OTH OTH HEAD HEAD HEAD HEAD HEAD HEAD OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH REL OTH OTH OTH OTH OTH OTH OTH TAIL TAIL TAIL TAIL TAIL TAIL OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH