{TAIL ~ These compounds} are useful in the treatment of diseases of the central nervous system, the cardiovascular system, {HEAD ~ the pulmonary system}, the gastrointestinal system and the endocrinologic system 
{ TAIL ~ These compounds } are useful in the treatment of diseases of the central nervous system , the cardiovascular system , { HEAD ~ the pulmonary system } , the gastrointestinal system and the endocrinologic system
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