The state change response is detected as result of {HEAD ~ the change} in {TAIL ~ ionic flow} through the membrane 
in
The state change response is detected as result of { HEAD ~ the change } in { TAIL ~ ionic flow } through the membrane
OTH OTH OTH OTH OTH OTH OTH OTH OTH HEAD HEAD HEAD HEAD HEAD HEAD REL TAIL TAIL TAIL TAIL TAIL TAIL OTH OTH OTH