According to the methods, {TAIL ~ an unrearranged human immunoglobulin heavy chain transgene} is introduced into the germline of a non human animal to produce a transgenic non human animal having {HEAD ~ the transgene} in its somatic and germ cells 
According to the methods , { TAIL ~ an unrearranged human immunoglobulin heavy chain transgene } is introduced into the germline of a non human animal to produce a transgenic non human animal having { HEAD ~ the transgene } in its somatic and germ cells
OTH OTH OTH OTH OTH TAIL TAIL TAIL TAIL TAIL TAIL TAIL TAIL TAIL TAIL TAIL OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH HEAD HEAD HEAD HEAD HEAD HEAD OTH OTH OTH OTH OTH OTH