The present invention also comprise the use in vaccine investigation with {HEAD ~ VLPs} produced by modified HPV 16 L1, {TAIL ~ HPV} 58 L1, HPV 18 L1, HPV 6 L1 and HPV 11 L1 genes as DNA vaccines or other formats 
produced by
The present invention also comprise the use in vaccine investigation with { HEAD ~ VLPs } produced by modified HPV 16 L1 , { TAIL ~ HPV } 58 L1 , HPV 18 L1 , HPV 6 L1 and HPV 11 L1 genes as DNA vaccines or other formats
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