A novel gene 251P5G2 and its encoded protein, and variants thereof, are described wherein 251P5G2 exhibits tissue specific expression in normal adult tissue, and is aberrantly expressed in the cancers listed in {TAIL ~ Table I. Consequently}, 251P5G2 provides a diagnostic, prognostic, prophylactic and therapeutic target for {HEAD ~ cancer} 
A novel gene 251P5G2 and its encoded protein , and variants thereof , are described wherein 251P5G2 exhibits tissue specific expression in normal adult tissue , and is aberrantly expressed in the cancers listed in { TAIL ~ Table I. Consequently } , 251P5G2 provides a diagnostic , prognostic , prophylactic and therapeutic target for { HEAD ~ cancer }
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