Such asynchrony can, in some patients, lead to ineffective ventilation and may increase {HEAD ~ the work} of {TAIL ~ breathing} 
of
Such asynchrony can , in some patients , lead to ineffective ventilation and may increase { HEAD ~ the work } of { TAIL ~ breathing }
OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH HEAD HEAD HEAD HEAD HEAD HEAD REL TAIL TAIL TAIL TAIL TAIL