Provided are 4 quinolone derivatives effective in inhibiting or eliminating the viability of at least one of the stages in the life cycle of the malarial parasite, and to show a reduced propensity to induce resistance to {HEAD ~ the compound} by {TAIL ~ the target parasite} 
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Provided are 4 quinolone derivatives effective in inhibiting or eliminating the viability of at least one of the stages in the life cycle of the malarial parasite , and to show a reduced propensity to induce resistance to { HEAD ~ the compound } by { TAIL ~ the target parasite }
OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH HEAD HEAD HEAD HEAD HEAD HEAD REL TAIL TAIL TAIL TAIL TAIL TAIL TAIL