A detectable change is brought about as a result of the hybridization of the oligonucleotides on {HEAD ~ the nanoparticles} to {TAIL ~ the nucleic acid} 
to
A detectable change is brought about as a result of the hybridization of the oligonucleotides on { HEAD ~ the nanoparticles } to { TAIL ~ the nucleic acid }
OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH HEAD HEAD HEAD HEAD HEAD HEAD REL TAIL TAIL TAIL TAIL TAIL TAIL TAIL