Also provided are a method for vaccinating a mammal to produce an antibody against bacterial infection caused by Enterobacteriaceae family in central nervous system and peripheral blood circulation and a method of detecting or diagnosing bacterial infections caused by {HEAD ~ Enterobacteriaceae family} in central nervous system and {TAIL ~ peripheral blood circulation} in a mammal 
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Also provided are a method for vaccinating a mammal to produce an antibody against bacterial infection caused by Enterobacteriaceae family in central nervous system and peripheral blood circulation and a method of detecting or diagnosing bacterial infections caused by { HEAD ~ Enterobacteriaceae family } in central nervous system and { TAIL ~ peripheral blood circulation } in a mammal
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