b) allowing sufficient time for the dye conjugate to form {HEAD ~ a complex} with {TAIL ~ the complementary member}, said complex exhibiting a detectable optical response; and 
with
b ) allowing sufficient time for the dye conjugate to form { HEAD ~ a complex } with { TAIL ~ the complementary member } , said complex exhibiting a detectable optical response ; and
OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH HEAD HEAD HEAD HEAD HEAD HEAD REL TAIL TAIL TAIL TAIL TAIL TAIL TAIL OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH