Concentrates of one of the coagulation factors II, V and VIII or a mixture thereof or blood plasma free from one or more of the coagulation factors VII, IX, X, XI and XII can be prepared by adding a reducing substance comprised of dithiothreitol, dithioerythritol, lipoic acid, mercaptoethanol, or {HEAD ~ a borohydride} to {TAIL ~ blood} or plasma, dithiothreitol being preferred 
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Concentrates of one of the coagulation factors II , V and VIII or a mixture thereof or blood plasma free from one or more of the coagulation factors VII , IX , X , XI and XII can be prepared by adding a reducing substance comprised of dithiothreitol , dithioerythritol , lipoic acid , mercaptoethanol , or { HEAD ~ a borohydride } to { TAIL ~ blood } or plasma , dithiothreitol being preferred
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