IRS1 and {HEAD ~ IRS2} are {TAIL ~ part} of the insulin or insulin like growth factor signaling pathways, but also mediate some signals through other growth factors and cytokines, including IFNγ, IL2, IL4, IL7, IL9, IL13 or IL15, growth hormone, prolactin, or leptin 
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IRS1 and { HEAD ~ IRS2 } are { TAIL ~ part } of the insulin or insulin like growth factor signaling pathways , but also mediate some signals through other growth factors and cytokines , including IFNγ , IL2 , IL4 , IL7 , IL9 , IL13 or IL15 , growth hormone , prolactin , or leptin
OTH OTH HEAD HEAD HEAD HEAD HEAD REL TAIL TAIL TAIL TAIL TAIL OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH