In some embodiments of the methods, {HEAD ~ a mixture} comprising {TAIL ~ a sample} and a substrate for the enzyme is provided 
comprising
In some embodiments of the methods , { HEAD ~ a mixture } comprising { TAIL ~ a sample } and a substrate for the enzyme is provided
OTH OTH OTH OTH OTH OTH OTH HEAD HEAD HEAD HEAD HEAD HEAD REL TAIL TAIL TAIL TAIL TAIL TAIL OTH OTH OTH OTH OTH OTH OTH OTH