Apparatus and methods are described for pharmaceutical grade manufacture {HEAD ~ extrachromosomal nucleic acids} from cell lysates using flotation to separate and eliminate undesired insoluble cellular debris including chromosomal DNA from {TAIL ~ the lysates} 
Apparatus and methods are described for pharmaceutical grade manufacture { HEAD ~ extrachromosomal nucleic acids } from cell lysates using flotation to separate and eliminate undesired insoluble cellular debris including chromosomal DNA from { TAIL ~ the lysates }
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