Breeding of {HEAD ~ the human heavy chain transgenic animals} with {TAIL ~ transgenic non human animals} containing a human immunoglobulin light chain transgene produces transgenic non human animals containing a human heavy chain transgene of the invention and a human light chain transgene 
with
Breeding of { HEAD ~ the human heavy chain transgenic animals } with { TAIL ~ transgenic non human animals } containing a human immunoglobulin light chain transgene produces transgenic non human animals containing a human heavy chain transgene of the invention and a human light chain transgene
OTH OTH HEAD HEAD HEAD HEAD HEAD HEAD HEAD HEAD HEAD HEAD REL TAIL TAIL TAIL TAIL TAIL TAIL TAIL TAIL OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH