While it has an inhibitory effect on AR in {HEAD ~ hormone sensitive prostate cancer}, it fails to suppress AR when cancer becomes {TAIL ~ hormone refractory} 
While it has an inhibitory effect on AR in { HEAD ~ hormone sensitive prostate cancer } , it fails to suppress AR when cancer becomes { TAIL ~ hormone refractory }
OTH OTH OTH OTH OTH OTH OTH OTH OTH HEAD HEAD HEAD HEAD HEAD HEAD HEAD HEAD OTH OTH OTH OTH OTH OTH OTH OTH OTH TAIL TAIL TAIL TAIL TAIL TAIL