{HEAD ~ The determination} of an effective dose is well within {TAIL ~ the capability} of those skilled in the art 
is well within
{ HEAD ~ The determination } of an effective dose is well within { TAIL ~ the capability } of those skilled in the art
HEAD HEAD HEAD HEAD HEAD HEAD OTH OTH OTH OTH REL REL REL TAIL TAIL TAIL TAIL TAIL TAIL OTH OTH OTH OTH OTH OTH