Formation of an ester or an amide of the disulfide compound led to not only prolongation of the duration but also improvement of absorption characteristics as a result of {HEAD ~ increase} of {TAIL ~ lipophilicity} 
of
Formation of an ester or an amide of the disulfide compound led to not only prolongation of the duration but also improvement of absorption characteristics as a result of { HEAD ~ increase } of { TAIL ~ lipophilicity }
OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH HEAD HEAD HEAD HEAD HEAD REL TAIL TAIL TAIL TAIL TAIL