Random four amino acid copolymers {HEAD ~ VYAK} and tryptophan containing VWAK were efficacious in alleviating severity and {TAIL ~ duration} of symptoms of EAE induced by MBP 85 99 , in a humanized mouse model expressing genes for both an HLA DR 2 linked to multiple sclerosis in humans and for a T cell receptor from an MS patient 
efficacious in alleviating
Random four amino acid copolymers { HEAD ~ VYAK } and tryptophan containing VWAK were efficacious in alleviating severity and { TAIL ~ duration } of symptoms of EAE induced by MBP 85 99 , in a humanized mouse model expressing genes for both an HLA DR 2 linked to multiple sclerosis in humans and for a T cell receptor from an MS patient
OTH OTH OTH OTH OTH HEAD HEAD HEAD HEAD HEAD OTH OTH OTH OTH OTH REL REL REL OTH OTH TAIL TAIL TAIL TAIL TAIL OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH