Of particular relevance is {HEAD ~ the marked increase} in the expression of genes associated with the production of gamma interferon, a potent antiviral agent and {TAIL ~ regulator} of the immune response 
Of particular relevance is { HEAD ~ the marked increase } in the expression of genes associated with the production of gamma interferon , a potent antiviral agent and { TAIL ~ regulator } of the immune response
OTH OTH OTH OTH HEAD HEAD HEAD HEAD HEAD HEAD HEAD OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH TAIL TAIL TAIL TAIL TAIL OTH OTH OTH OTH