{HEAD ~ The method} 1, wherein said {TAIL ~ tropic acid} or topically effective salt thereof is applied periodically for a period of time sufficient to achieve at least a clinically discernable reduction of said wrinkle 
wherein
{ HEAD ~ The method } 1 , wherein said { TAIL ~ tropic acid } or topically effective salt thereof is applied periodically for a period of time sufficient to achieve at least a clinically discernable reduction of said wrinkle
HEAD HEAD HEAD HEAD HEAD HEAD OTH OTH REL OTH TAIL TAIL TAIL TAIL TAIL TAIL OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH