Yet more particularly, the exemplary age regulatory element 5′ has been discovered to regulate stable gene expression over time in vivo, while {HEAD ~ the exemplary age regulatory element} 3′ has been discovered to regulate increased gene expression over time in {TAIL ~ vivo} 
Yet more particularly , the exemplary age regulatory element 5′ has been discovered to regulate stable gene expression over time in vivo , while { HEAD ~ the exemplary age regulatory element } 3′ has been discovered to regulate increased gene expression over time in { TAIL ~ vivo }
OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH HEAD HEAD HEAD HEAD HEAD HEAD HEAD HEAD HEAD OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH TAIL TAIL TAIL TAIL TAIL