In another embodiment, {TAIL ~ the water soluble and non peptidic polymer} has the structure HO POLYa Rq and the 1 benzotriazolylcarbonate ester of {HEAD ~ the water} soluble and non peptidic polymer has the structure 
In another embodiment , { TAIL ~ the water soluble and non peptidic polymer } has the structure HO POLYa Rq and the 1 benzotriazolylcarbonate ester of { HEAD ~ the water } soluble and non peptidic polymer has the structure
OTH OTH OTH OTH TAIL TAIL TAIL TAIL TAIL TAIL TAIL TAIL TAIL TAIL TAIL OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH HEAD HEAD HEAD HEAD HEAD HEAD OTH OTH OTH OTH OTH OTH OTH OTH