By performing the adding step, there is downregulating of the expression of {TAIL ~ colony intracellular bound bFGF}, and by performing the downregulating step, there is {HEAD ~ inhibiting} of bFGF promoted growth of cells in the colony 
By performing the adding step , there is downregulating of the expression of { TAIL ~ colony intracellular bound bFGF } , and by performing the downregulating step , there is { HEAD ~ inhibiting } of bFGF promoted growth of cells in the colony
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