As a result of earnest investigation of the structure of solid reagent in consideration of {HEAD ~ such circumstances}, the present inventors have found that the above problem can be solved by the provision of a clearance between {TAIL ~ the reagent layer} and the support so that the reagent layer is brought in contact with air from the support side 
As a result of earnest investigation of the structure of solid reagent in consideration of { HEAD ~ such circumstances } , the present inventors have found that the above problem can be solved by the provision of a clearance between { TAIL ~ the reagent layer } and the support so that the reagent layer is brought in contact with air from the support side
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