In certain embodiments, key structural features of the compounds disclosed herein appear to include the placement of {HEAD ~ a heterocyclylalkyl or heteroaralkyl group para} to {TAIL ~ the carboxyl group} in niacin 
to
In certain embodiments , key structural features of the compounds disclosed herein appear to include the placement of { HEAD ~ a heterocyclylalkyl or heteroaralkyl group para } to { TAIL ~ the carboxyl group } in niacin
OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH HEAD HEAD HEAD HEAD HEAD HEAD HEAD HEAD HEAD HEAD REL TAIL TAIL TAIL TAIL TAIL TAIL TAIL OTH OTH