Optionally, {TAIL ~ the pharmaceutical composition} of the invention may comprise a compound of formula I combined with one or more other pharmacologically active compounds, e.g. an antidiabetic or other pharmacologically active material, including compounds for the treatment and prophylaxis of insulin resistance and diseases wherein insulin resistance is {HEAD ~ the pathophysiological mechanism} 
Optionally , { TAIL ~ the pharmaceutical composition } of the invention may comprise a compound of formula I combined with one or more other pharmacologically active compounds , e.g. an antidiabetic or other pharmacologically active material , including compounds for the treatment and prophylaxis of insulin resistance and diseases wherein insulin resistance is { HEAD ~ the pathophysiological mechanism }
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