A compound 1, or a stereoisomer or tautomer thereof, or {TAIL ~ a pharmaceutically acceptable salt} of {HEAD ~ said compound}, said stereoisomer, or said tautomer, wherein 
A compound 1 , or a stereoisomer or tautomer thereof , or { TAIL ~ a pharmaceutically acceptable salt } of { HEAD ~ said compound } , said stereoisomer , or said tautomer , wherein
OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH TAIL TAIL TAIL TAIL TAIL TAIL TAIL TAIL OTH HEAD HEAD HEAD HEAD HEAD HEAD OTH OTH OTH OTH OTH OTH OTH OTH OTH