By upregulating {TAIL ~ the levels} or functional activity of IRS2, insulin is used more efficiently by the body to control {HEAD ~ nutrient levels} 
By upregulating { TAIL ~ the levels } or functional activity of IRS2 , insulin is used more efficiently by the body to control { HEAD ~ nutrient levels }
OTH OTH TAIL TAIL TAIL TAIL TAIL TAIL OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH HEAD HEAD HEAD HEAD HEAD HEAD