To achieve {TAIL ~ efficient signal generation}, the invention can exploit either the intrinsic optical properties of the microcolonies or {HEAD ~ various externally applied labeling reagents} 
To achieve
To achieve { TAIL ~ efficient signal generation } , the invention can exploit either the intrinsic optical properties of the microcolonies or { HEAD ~ various externally applied labeling reagents }
REL REL TAIL TAIL TAIL TAIL TAIL TAIL TAIL OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH HEAD HEAD HEAD HEAD HEAD HEAD HEAD HEAD HEAD