Formation of {TAIL ~ an ester} or {HEAD ~ an amide} of the disulfide compound led to not only prolongation of the duration but also improvement of absorption characteristics as a result of increase of lipophilicity 
Formation of { TAIL ~ an ester } or { HEAD ~ an amide } of the disulfide compound led to not only prolongation of the duration but also improvement of absorption characteristics as a result of increase of lipophilicity
OTH OTH TAIL TAIL TAIL TAIL TAIL TAIL OTH HEAD HEAD HEAD HEAD HEAD HEAD OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH