Also provided are methods to identify compositions capable of treating cholesterol related disease states, comprising a. contacting a test composition with Na/K ATPase; and b. identifying if step a. results in antagonizing the ability of cholesterol to bind to {HEAD ~ the CRAC domain} of {TAIL ~ the α1 subunit} of Na/K ATPase 
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Also provided are methods to identify compositions capable of treating cholesterol related disease states , comprising a. contacting a test composition with Na / K ATPase ; and b. identifying if step a. results in antagonizing the ability of cholesterol to bind to { HEAD ~ the CRAC domain } of { TAIL ~ the α1 subunit } of Na / K ATPase
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