The development of 5 HT3 agents originated from work carried out with metoclopramide , which is marketed for use in the treatment of {HEAD ~ nausea} and vomiting at {TAIL ~ high doses} 
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The development of 5 HT3 agents originated from work carried out with metoclopramide , which is marketed for use in the treatment of { HEAD ~ nausea } and vomiting at { TAIL ~ high doses }
OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH HEAD HEAD HEAD HEAD HEAD OTH OTH REL TAIL TAIL TAIL TAIL TAIL TAIL