The present invention overcomes a significant disadvantage of the prior art, since prior methods could not constrain the formation or deposition of biomolecules to a small region, due to {HEAD ~ the inability} to localize the synthesis process or to restrict {TAIL ~ the migration} of materials to prevent adjacent “spots” from diffusing into each other 
to restrict
The present invention overcomes a significant disadvantage of the prior art , since prior methods could not constrain the formation or deposition of biomolecules to a small region , due to { HEAD ~ the inability } to localize the synthesis process or to restrict { TAIL ~ the migration } of materials to prevent adjacent “ spots ” from diffusing into each other
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