Specifically, the controlled release capsule can be designed such that the release of the active substance can be delayed for a desired period of time, e.g., a number of hours, days or weeks, followed by the relatively rapid release of the encapsulated, breaker to {HEAD ~ the formation} at {TAIL ~ the desired time} 
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Specifically , the controlled release capsule can be designed such that the release of the active substance can be delayed for a desired period of time , e.g. , a number of hours , days or weeks , followed by the relatively rapid release of the encapsulated , breaker to { HEAD ~ the formation } at { TAIL ~ the desired time }
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