A composition 3, wherein {TAIL ~ the additional therapeutic agent} is selected from the group of: an antibody, an enzyme inhibitor, {HEAD ~ an antibacterial}, an antiviral, a steroid, a nonsteroidal anti inflammatory, an antimetabolite, a cytokine, a cytokine blocking agent, an adhesion molecule blocking agent, and a soluble cytokine receptor 
A composition 3 , wherein { TAIL ~ the additional therapeutic agent } is selected from the group of : an antibody , an enzyme inhibitor , { HEAD ~ an antibacterial } , an antiviral , a steroid , a nonsteroidal anti inflammatory , an antimetabolite , a cytokine , a cytokine blocking agent , an adhesion molecule blocking agent , and a soluble cytokine receptor
OTH OTH OTH OTH OTH TAIL TAIL TAIL TAIL TAIL TAIL TAIL TAIL OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH HEAD HEAD HEAD HEAD HEAD HEAD OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH