Optionally, {HEAD ~ the pharmaceutical composition} of the invention may comprise {TAIL ~ a compound} of formula I combined with one or more other pharmacologically active compounds, e.g. an antidiabetic or other pharmacologically active material, including compounds for the treatment and prophylaxis of insulin resistance and diseases wherein insulin resistance is the pathophysiological mechanism 
comprise
Optionally , { HEAD ~ the pharmaceutical composition } of the invention may comprise { TAIL ~ a compound } of formula I combined with one or more other pharmacologically active compounds , e.g. an antidiabetic or other pharmacologically active material , including compounds for the treatment and prophylaxis of insulin resistance and diseases wherein insulin resistance is the pathophysiological mechanism
OTH OTH HEAD HEAD HEAD HEAD HEAD HEAD HEAD OTH OTH OTH OTH REL TAIL TAIL TAIL TAIL TAIL TAIL OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH