In one embodiment, the present invention provides a method of solid phase synthesis that includes providing an azlactone functionalized support; reacting the azlactone functionalized support with {TAIL ~ a linker molecule} to form a linker functionalized support having a linker attached to the azlactone functionalized support; and conducting {HEAD ~ one or more reactions} on the linker functionalized support 
In one embodiment , the present invention provides a method of solid phase synthesis that includes providing an azlactone functionalized support ; reacting the azlactone functionalized support with { TAIL ~ a linker molecule } to form a linker functionalized support having a linker attached to the azlactone functionalized support ; and conducting { HEAD ~ one or more reactions } on the linker functionalized support
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