{HEAD ~ Such combined use} of substrate and oxygen supplier simplifies the manufacture of the implement and reduces {TAIL ~ the cost} 
reduces
{ HEAD ~ Such combined use } of substrate and oxygen supplier simplifies the manufacture of the implement and reduces { TAIL ~ the cost }
HEAD HEAD HEAD HEAD HEAD HEAD HEAD OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH REL TAIL TAIL TAIL TAIL TAIL TAIL