According to the methods, an unrearranged human immunoglobulin heavy chain transgene is introduced into the germline of a non human animal to produce {HEAD ~ a transgenic non human animal} having {TAIL ~ the transgene} in its somatic and germ cells 
having
According to the methods , an unrearranged human immunoglobulin heavy chain transgene is introduced into the germline of a non human animal to produce { HEAD ~ a transgenic non human animal } having { TAIL ~ the transgene } in its somatic and germ cells
OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH HEAD HEAD HEAD HEAD HEAD HEAD HEAD HEAD HEAD REL TAIL TAIL TAIL TAIL TAIL TAIL OTH OTH OTH OTH OTH OTH