This invention relates generally to novel triazolone and triazolethione derivatives as {TAIL ~ inhibitors} of matrix metalloproteinases , TNF α converting {HEAD ~ enzyme} , aggrecanase or a combination thereof, pharmaceutical compositions containing the same, and methods of using the same 
This invention relates generally to novel triazolone and triazolethione derivatives as { TAIL ~ inhibitors } of matrix metalloproteinases , TNF α converting { HEAD ~ enzyme } , aggrecanase or a combination thereof , pharmaceutical compositions containing the same , and methods of using the same
OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH TAIL TAIL TAIL TAIL TAIL OTH OTH OTH OTH OTH OTH OTH HEAD HEAD HEAD HEAD HEAD OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH