However, {HEAD ~ the inclusion} of a human gamma constant region on a transgene is not required to achieve {TAIL ~ such maturation} 
not required to achieve
However , { HEAD ~ the inclusion } of a human gamma constant region on a transgene is not required to achieve { TAIL ~ such maturation }
OTH OTH HEAD HEAD HEAD HEAD HEAD HEAD OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH REL REL REL REL TAIL TAIL TAIL TAIL TAIL TAIL