{HEAD ~ The epoxides} then spontaneously hydrolyze to {TAIL ~ intermediates} that can be further metabolized 
spontaneously hydrolyze to
{ HEAD ~ The epoxides } then spontaneously hydrolyze to { TAIL ~ intermediates } that can be further metabolized
HEAD HEAD HEAD HEAD HEAD HEAD OTH REL REL REL TAIL TAIL TAIL TAIL TAIL OTH OTH OTH OTH OTH