Compound VI is contacted with {TAIL ~ 2.4 difluorobenzylamine} under coupling {HEAD ~ conditions} to form —N 3 methyl 6 5,7 dioxo 2,3,5,7,11,11a hexahydrooxazolopyridopyrazine 8 carboxamide  
Compound VI is contacted with { TAIL ~ 2.4 difluorobenzylamine } under coupling { HEAD ~ conditions } to form — N 3 methyl 6 5,7 dioxo 2,3,5,7,11,11a hexahydrooxazolopyridopyrazine 8 carboxamide
OTH OTH OTH OTH OTH TAIL TAIL TAIL TAIL TAIL TAIL OTH OTH HEAD HEAD HEAD HEAD HEAD OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH