In the examples of the invention, {TAIL ~ the siRNA} is {HEAD ~ siTOPK} 1 having a first strand as set forth in SEQ ID 
In the examples of the invention , { TAIL ~ the siRNA } is { HEAD ~ siTOPK } 1 having a first strand as set forth in SEQ ID
OTH OTH OTH OTH OTH OTH OTH TAIL TAIL TAIL TAIL TAIL TAIL OTH HEAD HEAD HEAD HEAD HEAD OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH