It is to be understood, however, that the observation that a particular mutation or pattern of mutations leads to changes in a given property in no way excludes the possibility that {HEAD ~ the mutation} in {TAIL ~ question} can also influence other properties 
in
It is to be understood , however , that the observation that a particular mutation or pattern of mutations leads to changes in a given property in no way excludes the possibility that { HEAD ~ the mutation } in { TAIL ~ question } can also influence other properties
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