The antifolates act as {HEAD ~ novel inhibitors} of {TAIL ~ dihydrofolate reductase} of Plasmodium falciparum in the treatment of malaria, including non resistant and drug resistant malaria 
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The antifolates act as { HEAD ~ novel inhibitors } of { TAIL ~ dihydrofolate reductase } of Plasmodium falciparum in the treatment of malaria , including non resistant and drug resistant malaria
OTH OTH OTH OTH HEAD HEAD HEAD HEAD HEAD HEAD REL TAIL TAIL TAIL TAIL TAIL TAIL OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH