{TAIL ~ The variant} 1, further comprising {HEAD ~ a mutation} selected from the group consisting of: 
{ TAIL ~ The variant } 1 , further comprising { HEAD ~ a mutation } selected from the group consisting of :
TAIL TAIL TAIL TAIL TAIL TAIL OTH OTH OTH OTH HEAD HEAD HEAD HEAD HEAD HEAD OTH OTH OTH OTH OTH OTH OTH