A method of opening ATP regulated potassium channels in a subject, said method comprising administration to the subject in need thereof an effective amount of {HEAD ~ a compound} selected from {TAIL ~ the group} consisting of: 
selected from
A method of opening ATP regulated potassium channels in a subject , said method comprising administration to the subject in need thereof an effective amount of { HEAD ~ a compound } selected from { TAIL ~ the group } consisting of :
OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH HEAD HEAD HEAD HEAD HEAD HEAD REL REL TAIL TAIL TAIL TAIL TAIL TAIL OTH OTH OTH