The present invention overcomes a significant disadvantage of the prior art, since prior methods could not constrain the formation or deposition of biomolecules to a small region, due to the inability to localize the synthesis process or to restrict {HEAD ~ the migration} of {TAIL ~ materials} to prevent adjacent “spots” from diffusing into each other 
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The present invention overcomes a significant disadvantage of the prior art , since prior methods could not constrain the formation or deposition of biomolecules to a small region , due to the inability to localize the synthesis process or to restrict { HEAD ~ the migration } of { TAIL ~ materials } to prevent adjacent “ spots ” from diffusing into each other
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