Some of the specific advantages of this invention may be: reduced fluctuation between Cmax and Cmin during {HEAD ~ the course} of {TAIL ~ treatment} and hence better therapeutic profile, reduced side effects, improved patient compliance, and improved bioavailability of the drug 
of
Some of the specific advantages of this invention may be : reduced fluctuation between Cmax and Cmin during { HEAD ~ the course } of { TAIL ~ treatment } and hence better therapeutic profile , reduced side effects , improved patient compliance , and improved bioavailability of the drug
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