Formation of an ester or {HEAD ~ an amide} of the disulfide compound led to not only prolongation of the duration but also {TAIL ~ improvement} of absorption characteristics as a result of increase of lipophilicity 
Formation of an ester or { HEAD ~ an amide } of the disulfide compound led to not only prolongation of the duration but also { TAIL ~ improvement } of absorption characteristics as a result of increase of lipophilicity
OTH OTH OTH OTH OTH HEAD HEAD HEAD HEAD HEAD HEAD OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH TAIL TAIL TAIL TAIL TAIL OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH