a) providing a test cell which overproduces IRS2 and exhibits an increase in binding of an IRS2 binding protein to IRS2, relative to a control cell which produces {HEAD ~ IRS2} at {TAIL ~ a lower level}, or does not produce the protein at all, and which exhibits a lesser amount of binding of said protein to IRS2 
a ) providing a test cell which overproduces IRS2 and exhibits an increase in binding of an IRS2 binding protein to IRS2 , relative to a control cell which produces { HEAD ~ IRS2 } at { TAIL ~ a lower level } , or does not produce the protein at all , and which exhibits a lesser amount of binding of said protein to IRS2
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