A method for long term management of diabetes by avoiding the problems associated with {HEAD ~ tight control} of blood glucose concentrations, i.e., hypoglycemia tolerance and {TAIL ~ seizures}, while simultaneously avoiding the problems associated with conventional moderate control of blood glucose concentrations, i.e., pathological complications associated with hyperglycemia, such as nephropathy, retinopathy, etc 
A method for long term management of diabetes by avoiding the problems associated with { HEAD ~ tight control } of blood glucose concentrations , i.e. , hypoglycemia tolerance and { TAIL ~ seizures } , while simultaneously avoiding the problems associated with conventional moderate control of blood glucose concentrations , i.e. , pathological complications associated with hyperglycemia , such as nephropathy , retinopathy , etc
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