Provided are 4 quinolone derivatives effective in inhibiting or eliminating the viability of at least one of {HEAD ~ the stages} in {TAIL ~ the life cycle} of the malarial parasite, and to show a reduced propensity to induce resistance to the compound by the target parasite 
Provided are 4 quinolone derivatives effective in inhibiting or eliminating the viability of at least one of { HEAD ~ the stages } in { TAIL ~ the life cycle } of the malarial parasite , and to show a reduced propensity to induce resistance to the compound by the target parasite
OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH HEAD HEAD HEAD HEAD HEAD HEAD REL TAIL TAIL TAIL TAIL TAIL TAIL TAIL OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH