Delivery of fibrinolytic agents mainly to a specific organ, such as for example to the lungs, allows to substantially improve the specificity and {HEAD ~ efficacy} of thrombolytic therapy by allowing local delivery of the fibrinolytic agent, thereby reducing the risks of major bleeding in the therapy of {TAIL ~ the organ} 
Delivery of fibrinolytic agents mainly to a specific organ , such as for example to the lungs , allows to substantially improve the specificity and { HEAD ~ efficacy } of thrombolytic therapy by allowing local delivery of the fibrinolytic agent , thereby reducing the risks of major bleeding in the therapy of { TAIL ~ the organ }
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