b) causing {HEAD ~ the small molecule} to come into {TAIL ~ contact} with IRS2 or a complex comprising IRS2 and other cellular proteins in the cell; and 
b ) causing { HEAD ~ the small molecule } to come into { TAIL ~ contact } with IRS2 or a complex comprising IRS2 and other cellular proteins in the cell ; and
OTH OTH OTH HEAD HEAD HEAD HEAD HEAD HEAD HEAD REL REL REL TAIL TAIL TAIL TAIL TAIL OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH