In addition, factors associated with the particular patient being treated, including patient age, weight, diet and time of administration, will result in {HEAD ~ the need} to adjust {TAIL ~ dosages} 
In addition , factors associated with the particular patient being treated , including patient age , weight , diet and time of administration , will result in { HEAD ~ the need } to adjust { TAIL ~ dosages }
OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH HEAD HEAD HEAD HEAD HEAD HEAD REL REL TAIL TAIL TAIL TAIL TAIL