{HEAD ~ Such asynchrony} can, in some patients, lead to {TAIL ~ ineffective ventilation} and may increase the work of breathing 
{ HEAD ~ Such asynchrony } can , in some patients , lead to { TAIL ~ ineffective ventilation } and may increase the work of breathing
HEAD HEAD HEAD HEAD HEAD HEAD OTH OTH OTH OTH OTH OTH REL REL TAIL TAIL TAIL TAIL TAIL TAIL OTH OTH OTH OTH OTH OTH OTH