Accordingly, the method of {TAIL ~ the present invention} in which the activity of the tested substance having an inhibiting or promoting {HEAD ~ action} on the production of FXIIa is measured is very highly useful in screening compounds or drugs related to blood clotting and fibrinolysis systems 
Accordingly , the method of { TAIL ~ the present invention } in which the activity of the tested substance having an inhibiting or promoting { HEAD ~ action } on the production of FXIIa is measured is very highly useful in screening compounds or drugs related to blood clotting and fibrinolysis systems
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