In addition, {HEAD ~ factors} associated with the particular patient being treated, including patient age, weight, diet and time of administration, will result in {TAIL ~ the need} to adjust dosages 
In addition , { HEAD ~ factors } associated with the particular patient being treated , including patient age , weight , diet and time of administration , will result in { TAIL ~ the need } to adjust dosages
OTH OTH OTH HEAD HEAD HEAD HEAD HEAD OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH REL REL TAIL TAIL TAIL TAIL TAIL TAIL OTH OTH OTH