As a result of earnest investigation of the structure of solid reagent in consideration of such circumstances, the present inventors have found that the above problem can be solved by the provision of a clearance between the reagent layer and the support so that the reagent layer is brought in contact with {HEAD ~ air} from {TAIL ~ the support side} 
As a result of earnest investigation of the structure of solid reagent in consideration of such circumstances , the present inventors have found that the above problem can be solved by the provision of a clearance between the reagent layer and the support so that the reagent layer is brought in contact with { HEAD ~ air } from { TAIL ~ the support side }
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