In {TAIL ~ specific aspects}, the oligonucleotides inhibit {HEAD ~ HIF1α expression} and activity 
In { TAIL ~ specific aspects } , the oligonucleotides inhibit { HEAD ~ HIF1α expression } and activity
OTH TAIL TAIL TAIL TAIL TAIL TAIL OTH OTH OTH OTH HEAD HEAD HEAD HEAD HEAD HEAD OTH OTH