Prior to reaction, {HEAD ~ the reaction mixure} is given an effective amount of {TAIL ~ a non ionic detergent}, and agitated 
Prior to reaction , { HEAD ~ the reaction mixure } is given an effective amount of { TAIL ~ a non ionic detergent } , and agitated
OTH OTH OTH OTH HEAD HEAD HEAD HEAD HEAD HEAD HEAD OTH OTH OTH OTH OTH OTH TAIL TAIL TAIL TAIL TAIL TAIL TAIL TAIL OTH OTH OTH