{HEAD ~ The development} of {TAIL ~ 5 HT3 agents} originated from work carried out with metoclopramide , which is marketed for use in the treatment of nausea and vomiting at high doses 
{ HEAD ~ The development } of { TAIL ~ 5 HT3 agents } originated from work carried out with metoclopramide , which is marketed for use in the treatment of nausea and vomiting at high doses
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