A composition 3, wherein {HEAD ~ the additional therapeutic agent} is selected from {TAIL ~ the group} of: an antibody, an enzyme inhibitor, an antibacterial, an antiviral, a steroid, a nonsteroidal anti inflammatory, an antimetabolite, a cytokine, a cytokine blocking agent, an adhesion molecule blocking agent, and a soluble cytokine receptor 
A composition 3 , wherein { HEAD ~ the additional therapeutic agent } is selected from { TAIL ~ the group } of : an antibody , an enzyme inhibitor , an antibacterial , an antiviral , a steroid , a nonsteroidal anti inflammatory , an antimetabolite , a cytokine , a cytokine blocking agent , an adhesion molecule blocking agent , and a soluble cytokine receptor
OTH OTH OTH OTH OTH HEAD HEAD HEAD HEAD HEAD HEAD HEAD HEAD REL REL REL TAIL TAIL TAIL TAIL TAIL TAIL OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH OTH