{HEAD ~ Another object} of {TAIL ~ the present invention} is to provide a method for modulating cytotoxicity of an antibody by modulating the plasma half life of the antibody having cytotoxicity, an antibody with modulated cytotoxicity and a pharmaceutical composition, comprising the antibody, as well as a method of preparing the antibody and the pharmaceutical composition 
{ HEAD ~ Another object } of { TAIL ~ the present invention } is to provide a method for modulating cytotoxicity of an antibody by modulating the plasma half life of the antibody having cytotoxicity , an antibody with modulated cytotoxicity and a pharmaceutical composition , comprising the antibody , as well as a method of preparing the antibody and the pharmaceutical composition
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