Is screening with digital imaging using one retinal view adequate?
The specificity value and technical failure rate compare favourably with BDA guidelines. The low sensitivity for detection of any retinopathy reflects failure to detect minimal maculopathy and retinopathy outside the 45 degrees image. This could be improved by an additional nasal image and careful evaluation of macular images with a low threshold for slit-lamp biomicroscopy if image quality is poor.
Taken together, these results suggest a potential therapeutic use for BKT140 in multiple myeloma and leukemia patients.