Does n-acetylcysteine attenuate PKCbeta2 overexpression and myocardial hypertrophy in streptozotocin-induced diabetic rats?
The results suggest that PKCbeta(2) overexpression represents a mechanism causing hyperglycemia-mediated myocardial hypertrophy, which can be prevented by the antioxidant N-acetylcysteine.
These findings indicate that isovolemic hemodilution accelerates the plasma (not red cell) flow velocity in cerebral microvessels.