Is serum androgen bioactivity low in children with premature adrenarche?
Peripheral metabolism of adrenal androgen precursors may be required for any androgenic effects in PA. However, the limitations in the sensitivity of the bioassay developed herein may hide some differences between the PA and control children.
The newly designed protective sheaths result in smaller volumes of air emboli compared with standard sheaths in most situations evaluated. There was no significant difference in the volume of air emboli with use of protective clinical maneuvers. In some cases, the volume of the air emboli continued to increase during catheter insertion and sheath removal. There was no statistically significant difference between the use of protective sheaths and the use of the sheathless insertion technique.