Is tissue plasminogen activator combined with human recombinant deoxyribonuclease effective therapy for empyema in a rabbit model?
The combination of alteplase and rhDNase is more effective in the treatment of rabbit empyema than either agent alone. The intrapleural injection of alteplase alone or in combination with rhDNase leads to the production of large amounts of pleural fluid.
Our data highlight the use of NG-MAST in further defining gonococcal populations.