Does mental health history explain gender disparities in insomnia symptoms among young adults?
The gender disparity in insomnia symptoms may be driven by higher prevalence of affective disorders among women. This finding has implications for clinical treatment of both insomnia and depression, especially among women.
Populations of mature myofibers from all six extraocular muscles express N-CAM homogeneously on their cell surfaces. The orbital layer was almost completely N-CAM positive. When the staining pattern of the global layer of the rectus and oblique muscles is compared, not only did the rectus muscles have greater numbers of N-CAM-positive fibers, all rectus muscles showed both extracellular and intracellular N-CAM expression. This was in contrast to the oblique muscles, in which the number of N-CAM-positive fibers was reduced but N-CAM was only present extracellularly. Because of the exclusive involvement of the extraocular muscles in Graves' ophthalmopathy, the absence of N-CAM expression on other mature skeletal muscles, and the increased expression of N-CAM in those muscles (rectus) more affected in this disease, the authors postulate that N-CAM expression may at least be a marker for susceptibility to, if not play a clinically significant role in, the etiology and pathobiology of this disease. Complex patterns of association were demonstrated between N-CAM expression and myosin types, indicating that N-CAM-positive myofibers do not conform to a specific fiber type as traditionally defined.