Does rapid growth accelerate telomere attrition in a transgenic fish?
Our results are consistent with a trade-off between rapid growth and somatic (telomere) maintenance in growth-manipulated fish. Since telomere erosion reflects cellular ageing, our findings also support theories of ageing postulating that unrepaired somatic damage is associated with senescence.
Our data indicated that overexpression of miR-150 in NSCLC tissues has prognostic value.