Does ethyl pyruvate diminish the inflammatory response to lipopolysaccharide infusion in horses?
Ethyl pyruvate administered following LPS diminished the clinical effects of endotoxaemia and decreased proinflammatory gene expression in horses. Ethyl pyruvate suppressed expression of proinflammatory cytokines better than FM. However, FM was a superior anti-pyretic compared with EP. Ethyl pyruvate may have therapeutic applications in endotoxaemic horses.
The diameters of the common bile duct as measured on sonograms increase slightly after cholecystectomy. Most patients do not have significant compensatory dilatation of the duct after cholecystectomy.