Does maternal N-acetylcysteine suppress fetal inflammatory cytokine responses to maternal lipopolysaccharide?
Maternal N-acetylcysteine inhibits fetal cytokine responses to maternal lipopolysaccharide, even when given 2 hours after lipopolysaccharide injection. These results suggest that N-acetylcysteine may protect the fetus from sequelae of maternal inflammation.
Higher amniotic fluid MMP-2 and TIMP-2 levels are found in women who eventually develop preeclampsia.