Does activation of submucosal 5-HT ( 3 ) receptors elicit a somatostatin-dependent inhibition of ion secretion in rat colon?
Activation of neuronal 5-HT(3) receptors in the submucosal plexus of rat colon suppressed 5-HT-induced ion secretion by releasing somatostatin from submucosal neurons.
These results show that Sulf1 and Sulf2 play overlapping yet critical roles in mouse development and are redundant and essential for neonatal survival.