Does nucleos ( t ) ide analogue treatment reduce apoptotic activity in patients with chronic hepatitis B?
Decline of cell death parameters in association with decline of HBV-DNA and HBs-Antigen indicates a reduction in overall cell death activity during Nuc treatment supporting the concept that response to Nuc therapy reduces necroinflammatory activity and progression of liver disease.
In summary, our results suggest that autophagy may be a possible protective factor in inflammation induced by MSNs in macrophages.