Does miR-21 simultaneously regulate ERK1 signaling in HSC activation and hepatocyte EMT in hepatic fibrosis?
MiR-21 modulates ERK1 signaling and EMT in liver fibrosis by regulating SPRY2 and HNF4α expression. MiR-21 may serve as a potentially biomarker as well as intervention target for hepatic cirrhosis.
eIF3f may play an important role in recurrence. Its function and potential as a prognostic marker should be further verified in GC.