Does hypothyroidism affect the expression of electrogenic amiloride-sensitive sodium transport in rat colon?
Thyroid hormones have a permissive role in the regulation of electrogenic amiloride-sensitive Na+ transport by aldosterone.
We show that this novel therapeutic modality can significantly induce antitumor responses in vivo. These results support a role for p12 as a novel tumor growth suppressor gene therapy and suggest that optimization and/or combination with current therapies may hold considerable promise in preparation for clinical trials.