Do phosphodiesterase-5A and neutral endopeptidase activities in human adipocytes control atrial natriuretic peptide-mediated lipolysis?
Functional PDE-5A and NEP activities were present in human adipocytes, however these enzymes did not play a major role in the regulation of ANP-mediated lipolysis.
Rat renal interstitial fibroblasts shift the Th1/Th2 profile in vitro, and this may be another pathway by which renal interstitial fibroblasts promote fibrosis.