Do inhibition of proliferation of Pseudomonas aeruginosa by KGF in an experimental burn model using human cultured keratinocytes?
Many studies have been done on KGF, where its known properties were defined as a mitogen for keratinocytes [Munster AM. Cultured skin for massive burns: a prospective, controlled trial. Ann Surg 1996;224(3):372-7]. This method allows for a qualitative and quantitative evaluation in real time of the bacterial growth in wound sites after bacterial inoculation. KGF was involved in the reduction of bacterial viability. However, as KGF alone did not produce any effect on P. aeruginosa, it seems to modulate the skin innate immune response.
The effectiveness outcomes varied across case studies and the ability of the Madagascan equity funds to protect households against financial risk was ambiguous. To some extent, contextual factors explain these outcome variations. Consequently, nationwide policy should be designed with consideration of the broader health system context and incorporate measures to manage contextual factors to achieve benefit for the entire population.