Does tLK1B promote repair of UV-damaged DNA through chromatin remodeling by Asf1?
Our studies provide evidence for TLK1B-mediated phosphorylation of Asf1 triggering DNA repair. We suggest that this occurs via Asf1-mediated chromatin assembly at the sites of UV damage.
Higher blood pressure in children is associated with smaller retinal D(f), reflecting rarefaction of the retinal microvasculature. Retinal fractal analysis detects early subtle microvascular effects of elevated blood pressure, and may further the understanding of the genesis of ocular and systemic vascular complications of hypertension.