Is laparoscopic re-evaluation justified in cryptorchidism with previous negative open exploration?
Although a modest number of samples, our results underscore the prevalence of missed diagnosis. Obviously, laparoscopic re-exploration is indicated when a child with previous bilateral inguinal exploration presents with hormonal evidence of functioning gonadal tissue. Further we now recommend laparoscopic re-evaluation in most patients with nonpalpable testis and history of negative open exploration altogether.
Antitumor TTs that trigger MPT in isolated mitochondria might interact with components of the PTP to boost its Ca2+-sensitive transition from the closed to the open state and might be valuable to develop mitochondriotoxic drugs that directly activate early components of apoptosis.