Does mitochondrial dysfunction-mediated apoptosis resistance associate with defective heat shock protein response in African-American men with prostate cancer?
Restoration of mitochondrial function may provide new option for reducing PCa health disparity among American men.
Rolipram promotes the maturation of OPCs, facilitates remyelination, and increases ERK phosphorylation. All of these actions are involved in an action against cuprizone-induced demyelination that may occur partly via the MEK-ERK pathway. Importantly, this may have therapeutic implications for MS.