Is promoter methylation of Wnt5a associated with microsatellite instability and BRAF V600E mutation in two large populations of colorectal cancer patients?
Methylation of Wnt5a is associated with distinct tumour subtypes, strengthening the evidence of an epigenetic-mediated Wnt bias in CRC.
The results underscore an important role of platelets in chronic liver damage and imply a new target for antifibrotic therapies.