Is the `` interferon sensitivity determining region '' of hepatitis C virus a stable sequence element?
Within the homogeneous patient group examined here, no correlation was found between the ISDR and the interferon response. Recent studies found only a small number of mutant type ISDRs in Europe. Additionally, our results indicate that the ISDR is a stable sequence element. This provides an explanation for the divergent data relating to the importance of the ISDR in different geographical regions.
Preservation solutions can protect muscle function and morphology in ischemia-reperfusion limbs and improve recipient survival rates after transplantation of long-term-preserved limbs.