Does mLH1 mediate PARP-dependent cell death in response to the methylating agent N-methyl-N-nitrosourea?
These novel data indicate an important role for MLH1 in signalling PARP-dependent cell death in response to the methylating agent MNU.
These studies indicate a critical role for resident pleural macrophages in sensing perturbation to the local microenvironment and orchestrating subsequent neutrophil infiltration.