Does mitogen-activated protein kinase phosphatase-1 modulate regional effects of injurious mechanical ventilation in rodent lungs?
Injurious ventilation induces MAPK in an MKP-1-dependent fashion. Prone positioning is protective and induces MKP-1. PG490-88 induced MKP-1 and was protective against high Vt in a nuclear factor-κB-dependent manner. MKP-1 is a potential target for modulating regional effects of injurious ventilation.
Knowledge deficits continue to exist related to OC, emphasizing the need for NPs to be aware of risk factors, symptoms, and early detection options for women with average risk. Many NP students erroneously believed a Pap test was an effective screening tool for OC.