Is human leucocyte antigen class I and class II antigen expression in malignant fibrous histiocytoma , fibrosarcoma and dermatofibrosarcoma protuberans significantly downregulated?
The data presented suggest for the first time a high frequency of HLA class I and class II abnormalities in malignant fibrous histiocytomas, fibrosarcomas and dermatofibrosarcoma protuberans in vivo.
It is not known whether our patients with isolated aortitis represent variants of GCA or TA, nor is it known how they will evolve, but we can certainly conclude that these patients have a different epidemiologic and clinical profile, and do not necessarily represent two sides of the same coin.