Is the polarity of relapse/recurrence in bipolar-I disorder patients related to serum lithium levels?
The results indicate that within the currently accepted therapeutic range (0.4-1.1 mmol/l), the relative risk for depressive vs. hypomanic/manic/mixed relapses/recurrences may be associated with higher lithium levels. Therefore, lithium levels at the lower range of the therapeutic spectrum may be sufficient for the optimal prevention of depressive episodes whereas higher lithium levels within this range may be needed for optimal protection against manic/mixed episodes.
Doses of 100 mg of iron sucrose are associated with the presence of NTBI and enhanced S. aureus growth.