Is aBCB1 G2677 allele associated with high dose requirement of cyclosporin A to prevent renal allograft rejection in North India?
Identification of ABCB12677GG patients may have a clinically significant impact on allograft outcome and may be helpful in providing pre-transplant pharmacogenetic information to individualize CsA dosing.
RELMbeta and RELMgamma form homo/heterodimers, which are secreted into the circulation. Serum concentrations of RELMbeta and RELMgamma may be a novel intestinal-tract-mediating regulator of insulin sensitivity, possibly involved in insulin resistance induced by obesity and a high-fat diet.