Are hand deformities important signs of disease severity in patients with early rheumatoid arthritis?
More than half of the patients in this early RA cohort had developed hand deformities after 10 years. Most deformities occurred during the first year of the disease. Presence of hand deformities had an impact on daily life function and added useful prognostic information, being an early sign of a more severe disease.
Our findings imply that Gpr97 might not be required for the development of airway inflammation in OVA-induced allergic asthma in mice.