Does in vitro complement activation favoring soluble C5b-9 complex formation alter myocellular sodium homeostasis?
Zymosan-activated rat serum (presumed SC5b-9 enriched) selectively alters Na(+) homeostasis in isolated fast-twitch skeletal muscle. The mechanisms for such effects may be linked to G-proteins, Ca(2+) flux and Na(+),K(+)-adenosine triphosphatase pump binding site blockade.
The risk of developing DVT may be higher in users of combined estrogen-progestin HRT than in users of estrogen-only HRT.