Does sevelamer carbonate reduce inflammation and endotoxemia in an animal model of uremia?
In conclusion, induction of renal failure triggered inflammation and induced endotoxemia in this experimental model of chronic kidney disease, which were reduced by sevelamer treatment. This data suggests that sevelamer carbonate induces an anti-inflammatory effect in parallel to a reduction in ET.
The results of the present study show that multi-tract PCNL for appropriately chosen stones/patients has similar safety and effectiveness as single PCNL in patients with smaller and less complex stones.