Left ventricular hypertrophy in chronic kidney disease. Is pulse pressure an independent risk factor?
This study has shown a strong association between chronic kidney disease (CKD) and LVH in pre dialysis patients. Pulse pressure, SBP and anemia play an important role in the development of left ventricular hypertrophy in CKD patients.
Activation of canonical NF-kappaB subunits p50 and p65 as measured by nuclear expression is strongly associated with survival suggesting NF-kappaB as a prognostic factor in this disease. Primary tumor nuclear expression appears to be as good as, or better than, metastatic sites at predicting prognosis. Bcl-3 nuclear expression is also negatively associated with survival and deserves further study in CRC.