Does g protein beta3 subunit C825T polymorphism modify the presentation of temporal lobe epilepsy?
There was no increased frequency of TLE between the carriers of the TT genotype compared with the healthy controls and/or family members without epilepsy. However, the TLE patients with the TT genotype showed tendencies of a more severe disease phenotype.
Elevated aAbs against IL-17F correlate with disease activity in patients with ERA. This evidence suggests that anti-IL-17F aAbs may have a protective role in the pathogenesis of ERA.