Does a prostaglandin E2 receptor antagonist prevent pregnancies during a preclinical contraceptive trial with female macaques?
This is the first study to demonstrate that a PTGER2 antagonist can serve as an effective non-hormonal contraceptive in primates.
Although no ocular surface infection was observed, the patients under 100% autologous serum eye drops therapy should be closely monitored for clinical evidence of fungal and bacterial infections.