Does 2,3,7,8-tetrachlorodibenzo-p-dioxin reduce myocardial hypoxia and vascular endothelial growth factor expression during chick embryo development?
These results suggest that the myocardium may be a target of TCDD toxicity, resulting in reduced myocardial hypoxia, and HIF-1alpha and VEGF-A expression believed necessary for normal coronary development.
Exertional dyspnea was related to activation (oxygenation) of the prefrontal cortex in COPD patients and control subjects.