Does galectin-3 mediate bone marrow microenvironment-induced drug resistance in acute leukemia cells via Wnt/β-catenin signaling pathway?
Our results suggest that gal-3, a key factor mediating BMM-induced drug resistance, could be a novel therapeutic target in acute leukemia.
CSPG4 expression does not have any impact on survival and signaling activity of melanoma cells during PI3K/mTOR inhibition.