Is life expectancy reduced in differentiated thyroid cancer patients ≥ 45 years old with extensive local tumor invasion , lateral lymph node , or distant metastases at diagnosis and normal in all other DTC patients?
Life expectancy is not significantly reduced in 86% of DTC patients; only patients at least 45 yr old with extensive local invasion, lateral lymph node metastases, and/or distant metastases (TNM stages IVa, IVb, and IVc) at diagnosis showed a clearly lower life expectancy.
Medication Event Monitoring System data-cleaning based on diary entries did not affect the adherence-VL relationship.