Is the Y402H variant of complement factor H associated with age-related macular degeneration but not with diabetic retinal disease in the Go-DARTS study?
The ARMD-associated Y402H variant in CFH does not appear to be associated with diabetic retinal disease, although complement activation is involved in the pathoaetiology of both conditions.
Our data indicate that RV function is not depressed in morbid obesity despite increased RV afterload.