Is nucleotide change of codon 38 in the X gene of hepatitis B virus genotype C associated with an increased risk of hepatocellular carcinoma?
The codon-38 change in genotype C is an independent risk factor for the development of HCC and may serve as a useful molecular marker for predicting the clinical outcomes in patients infected with HBV.
Increased TREM-1 expression on monocytes is associated with both infectious and noninfectious inflammatory processes, and the levels of MHC-II expression is better correlated with the patient outcome.