Is C3435T polymorphism of MDR1 related to inflammatory bowel disease or colorectal cancer in Korean?
MDR1 C3435T polymorphism is also present in Korean and the dominant allele is C. However, there is no evidence that C3435T polymorphism of MDRI is associated to inflammatory bowel disease or colorectal cancer in Korean.
These results suggest that Dlx-2 may be involved in tumor progression via the regulation of metabolic stress-induced necrosis.