Does interferon alfa activate a lytic mechanism in ovarian and cervical carcinoma cells?
The ability to reveal the lytic potential of interferon alfa when protein synthesis is subsequently inhibited could have practical applications for the treatment of gynecologic malignancies.
In this study, we showed that treatment with PIO could ameliorate coronary insulin resistant and upregulate the expression of AdipoR1/R2. PIO showed an anti-atherogenic property via the activation of PPAR-γ, suppression of TNF-α overexpression in coronary and coronary VSMCs.