Do post-translational modifications enhance NT-proBNP and BNP production in acute decompensated heart failure?
These comprehensive results provide a paradigm for the post-translational modification of natriuretic peptides in ADHF: as proBNP glycosylation decreases, furin activity increases. This synergistically amplifies the processing of proBNP into BNP and NT-proBNP.
Common low-penetrance CRC risk SNPs were not associated with outcomes among patients with metastatic CRC.