Does methyl p-hydroxybenzoate cause pain sensation through activation of TRPA1 channels?
Our data indicate that methyl paraben is able to activate TRPA1 channels and can cause pain sensation. As such, methyl paraben provides a useful tool for investigating TRPA1 function and development of antinociceptive agents acting on TRPA1 channels.
Ultrasound is the first step in the staging of renal cancer before surgery; to assess. 2.5 and 7 in diameter CT scan is the gold standard for solid and cystic lesions.