Does cREB inhibit AP-2alpha expression to regulate the malignant phenotype of melanoma?
Since AP-2alpha regulates several genes associated with the metastatic potential of melanoma including c-KIT, VEGF, PAR-1, MCAM/MUC18, and p21(Waf1), our data identified CREB as a major regulator of the malignant melanoma phenotype.
We did not find any association between myeloid antigen positivity and clinical and laboratory features of ALL.