Is risk for cardiovascular autonomic neuropathy associated with the HLA-DR3/4 phenotype in type I diabetes mellitus?
The development of cardiovascular autonomic neuropathy in type I diabetes mellitus is strongly associated with the HLA-DR3/4 phenotype. Thus, genetic predisposition may play an important role in the development of this complication.
This study suggests a downward modulatory effect of the KP on CSF inflammation during BM.