Reliability of proliferation assessment by Ki-67 expression in neuroendocrine neoplasms: eyeballing or image analysis?
Assessment of the Ki-67 index by eyeballing correlates remarkably well with the Ki-67 index as calculated by image analysis and is therefore an accurate parameter. Moreover, it is significantly related to survival irrespective of the method used. Yet if the Ki-67 index is translated to grade, the grade should be interpreted with caution due to values around threshold levels.
Deprivation was associated with worse pre-operative general health status. However, given that the variation in pre-operative disease-specific health status by deprivation score was of small clinical significance and the limited power of the risk adjustment model, there is little evidence of socioeconomic inequity in access to three common elective surgical procedures.