Is [ Study of bone marrow microvessel density one of the diagnostic approaches in patients with Ph-negative chronic myeloproliferative diseases ]?
Bone marrow angiogenesis assessment (from MVD measurements) may be an additional criterion for the diagnosis of disease evolution and an additional criterion between ET and PMF in a prefibrotic stage.
Mortality (10% to 50%) is common due to the poor condition of the patients and the delay in diagnosis. Earlier diagnosis may lower the high morbidity and mortality associated with this condition.