Does lncRNA UCA1 promote epithelial-mesenchymal transition ( EMT ) of breast cancer cells via enhancing Wnt/beta-catenin signaling pathway?
UCA1 can modulate epithelial-mesenchymal transition (EMT) of MDA-MB-231 cells and knockdown of UCA1 impaired the mesenchymal properties. UCA1 upregulation increases invasiveness of breast cancer cells at least partly via activating the Wnt/β-catenin signaling pathway.
Maximum likelihood analysis and genetic distance calculations based on the full-length genomes of HBV strains isolated from patients and controls provided strong evidence for a common nosocomial source of infection for all 32 patient cases.