Does peroxiredoxin II negatively regulate lipopolysaccharide-induced osteoclast formation and bone loss via JNK and STAT3?
We suggest that PrxII could be useful in the development of a novel target for inflammatory bone loss.
Rotator cuff repair, especially in conjunction with glenosphere lateralization, produces an antagonistic effect that increases deltoid and joint loading. The long-term effects of this remain unknown; however, combining these factors may prove undesirable. Humeral lateralization improves joint compression through deltoid wrapping and increases the deltoid's mechanical advantage, and therefore, could be used in place of rotator cuff repair, thus avoiding its complications.