Is inhibition of alveolar neutrophil immigration in endotoxemia macrophage inflammatory protein 2 independent?
These data demonstrate that endotoxemia inhibits PMN migration despite similar MIP-2 concentrations in the alveolus. Sequential insults do not affect the inhibition of apoptosis. In vitro, PMN from endotoxemic animals display impaired chemotaxis to MIP-2 and interleukin-8. This may result in an inadequate host defense that contributes to increased ICU-acquired pneumonia in septic patients.
There is a clear clustering of components of infant microbiota based on the feeding method.