Is alpha-synuclein in the colon a biomarker for premotor Parkinson's disease?
This is the first demonstration of alpha-synuclein in colon tissue prior to onset of PD. Additional study is required to determine whether colonic mucosal biopsy may be a biomarker of premotor PD.
The deregulated miRNAs probably play a potential role in the pathogenesis of skeletal muscle wasting in burn trauma.