Does tLR2 mediate recognition of live Staphylococcus epidermidis and clearance of bacteremia?
TLR2 mediates recognition of live SE and clearance of SE bacteremia in vivo.
These results suggest that in vivo (1) statins directly increase PCSK9 expression while (2) fibrates affect PCSK9 expression indirectly through its modulation of cholesterol levels and (3) that these therapies could be improved by combination with a PCSK9 inhibitor, constituting a novel hypercholesterolemic therapy, since PCSK9 was significantly upregulated by both treatments.