Are pulsations of the ductus venosus blood velocity and diameter more pronounced at the outlet than at the inlet?
Both blood velocity and diameter pulsations are smaller at the inlet than at the outlet of the ductus venosus. The tapering shape of the vessel and the diameter differences at the junction with the umbilical vein are suggested to be important factors affecting the velocity waveform.
These results support a role for H1 and specifically H1G in susceptibility to DLB. However, the exact functional variant at the locus is still unknown, and additional studies are warranted to fully explain genetic risk of DLB at the MAPT locus.