Does mutant Parkin impair mitochondrial function and morphology in human fibroblasts?
Our results indicate that Parkin mutations cause abnormal mitochondrial function and morphology in non-neuronal human cells.
Psammaplin A, 5-aza-2'-deoxycytidine, and zebularine induce radiosensitivity in both A549 and U373MG cell lines, and suggest that this effect might be associated with the inhibition of DNA repair.