Does total tau in cerebrospinal fluid differentiate Alzheimer 's disease from vascular dementia?
CSF total tau clearly and simply differentiates AD from VD. CSF total tau in the incipient stage of AD and its increase in parallel with the progression of the disease may also provide a biochemical test to monitor the development of the disease.
The present data, in conjunction with earlier findings, support a theory that skull tap VEMP are mediated by two different mechanisms. It is suggested that skull tapping causes both skull vibration and head acceleration. Further, the VEMP would be the sum of the direction-independent vibration-induced response (from the sound-sensitive part of the saccule) and the direction-dependent head acceleration response (from other parts of the labyrinth).