Does expression analysis elucidate the roles of MAML1 and Twist1 in esophageal squamous cell carcinoma aggressiveness and metastasis?
We introduce Twist1 and MAML1 as new molecular markers of advanced tumor, which determine the characteristics and aggressive behavior of ESCC. Along with the emerging evidence of their role in different cellular processes and aberrations in various cancers, they are suggested as potentially interesting therapeutic targets to reverse a broad spectrum of functional aberrations that promote ESCC development.
The results of this study indicate that a combination of life circumstances, as well as cognitive factors were associated with late immunization.