Does lipopolysaccharide-binding protein inhibit toll-like receptor 2 activation by lipoteichoic acid in human odontoblast-like cells?
These results demonstrate that LBP reduces TLR2-dependent production of inflammatory cytokines by odontoblast-like cells. We suggest that in this way it could modulate host defense in human dental pulp.
A synthetic analogue of a fusogenic peptide domain from herpes simplex virus has been proven to improve cationic lipid-mediated transfection in vitro. The application of this fusogenic peptide will lead to improved strategies for transfection and successful gene therapy.