Does cyclosporin A inhibit monocyte tissue factor activation in cardiac transplant recipients?
This study demonstrates that TF activation, occurring in mononuclear cells of cardiac transplant recipients, is inhibited by treatment with CsA. Inhibition of monocyte TF induction by CsA may contribute to its successful use in cardiac transplant medicine and might be useful in managing further settings of vascular pathology also known to involve TF expression and NF-kappaB activation.
Besides traditional risk factors, IL-10 and RKF were important factors associated with vascular calcification in PD patients.