Is nerve regeneration after reconstruction with collagen nerve conduits terminated after 12 months?
Our results provide evidence that the long-term recovery of sensibility after digital nerve tubulization depends on the nerve gap length with better results in those < 10 mm. Nerve regeneration after tubulization seems not to be terminated after 12 months.
Our results indicate quantitative radiographic JSW measurements correlate with 4-year clinical outcomes. Since patients with narrower JSW at the onset of study had lower KOOS scores at 4 years even after controlling for 4-year change in JSW and baseline KOOS scores, clinical outcomes in knee OA may be predetermined once the disease process begins. These findings suggest early treatment with disease modifying therapies may be necessary to influence outcomes.