Does medial temporal lobe atrophy increase the specificity of cerebrospinal fluid biomarkers in Alzheimer disease with minor cerebrovascular changes?
P-tau correlates with the linear CT measure of MTA only in pure AD without CVC. Combined with the measure of MTA, the specificity of CSF biomarkers can be increased, but only in AD + CVC. The linear measurements of MTA are of value in AD diagnosis.
In the case of increased GGT levels, liver ultrasound should be performed, not only for diagnosis, but also for further risk stratification.