Does apocynin attenuate renal fibrosis via inhibition of NOXs-ROS-ERK-myofibroblast accumulation in UUO rats?
These results suggested that apocynin might exert beneficial effects on renal fibrosis by inhibition of NOXs activation and subsequent reduction of oxidative stress, ERK activation, and myofibroblast accumulation in UUO rats. Targeting NOXs may serve as a therapeutic strategy for the treatment of renal fibrosis.
No clinically relevant differences in absorption parameters were observed in patients with high and low levels of anxiety.