Are presence of epileptiform discharges on initial EEGs associated with failure of retention on first antiepileptic drug in newly diagnosed cryptogenic partial epilepsy : a 2-year observational study?
In newly diagnosed cryptogenic partial epilepsy, overall retention on the first AED was not significantly different from that in newly diagnosed partial epilepsy. In clinical practice, epileptiform discharges on the initial EEG could predict the failure of retention on the first AED for 2 years.
These results suggest that IL-36α and IL-36γ contribute to gut inflammation through the induction of proinflammatory mediators.