Are we failing workers with symptoms suggestive of occupational asthma?
Significant diagnostic delay currently occurs for patients with occupational asthma in the UK.
Like in epithelial cells or cell lines, transcription regulator YY1 is widely expressed in rodent fibroblasts. Removal of YY1 binding motifs can elevate in the context of the whole genome, the anchorage independent growth ability and the transforming capacity of HPV 16 on the mouse fibroblasts.