Does interleukin-18 stimulate a positive feedback loop during renal obstruction via interleukin-18 receptor?
Results reveal that interleukin-18 stimulates a positive feedback loop via interleukin-18 receptor during renal obstruction to stimulate interleukin-18 production and gene expression. The predominant cellular source of interleukin-18 production during renal obstruction appears to be tubular epithelial cells rather than infiltrating macrophages.
DM is an independent factor for poorer prognosis in patients who received curative therapy for localized HCC.