Is autonomic function associated with health-related quality of life in patients with end-stage renal disease : a case-control study?
Impaired autonomic function is significantly associated with fatigue and impaired QOL in dialysis patients.
The case suggests a prominent oestrogenic effect of centchroman on the uterus. This could be a significant adverse effect related to prolonged therapy. Lengthy intake of centchroman requires medical surveillance and long-term studies are needed.