Is introduction of point-of-care testing in Japanese outpatient clinics associated with improvement in time in therapeutic range in anticoagulant-treated patients?
The introduction of POC testing was associated with an improvement in TTR, mainly through a reduction in the time spent below the target INR.
Induction of tolerance to nitrates cannot be used to treat cluster headache. If pain is related to arterial dilatation the results point to extracerebral rather than cerebral arteries as the site of nociception. However, other peripheral and central pain-modulating effects of nitric oxide, the time courses of which are unknown, should also be taken into consideration.