Are statins associated with reduced use of steroids in inflammatory bowel disease : a retrospective cohort study?
In this large retrospective cohort study, statin use among persons with IBD was associated with reduced use of oral steroids, particularly for ulcerative colitis. Prospective clinical trials are needed to confirm whether adjuvant treatment of IBD with statin drugs may spare immunosuppressant therapy or ameliorate flares.
Our findings reflect a shifting health burden and an epidemiological transition, particularly in the Temuan and Bidayuh. These changes could be attributed to dietary habits, lifestyles and socio-economic factors brought about by urbanization.