Does inositol 1,4,5-trisphosphate-induced Ca2+ signalling is involve in estradiol-induced breast cancer epithelial cell growth?
Altogether, our results are in favour of a role of IICS in MCF-7 cell growth, and we hypothesize that the regulation of IP3R3 expression by E2 is involved in this effect.
By providing equivalent serum levels of FSH in older and younger reproductive aged women, this study demonstrates that the secretory capacity of recruited follicles is maintained in older reproductive aged women.