Do young dyspeptic patients consider upper gastro-intestinal endoscopy useful?
Young dyspeptic patients, patients with peptic ulcer disease seems to be the only group where endoscopy has significant value for choosing the optimal therapeutic option. Neither the reassurance by a negative endoscopy in the NUD group nor the detection of esophagitis in patients with GERD is of importance to subjective improvement.
These results suggest that CGRP plays an important role in the response of antral D and G cells to luminal acid and that local effector action of endogenous CGRP participates in regulation of antral regulatory peptide secretion.