Does delayed antagonism of calpain reduce excitotoxicity in cultured neurons?
The activation of calpain is among several enzymatic processes that contribute to the toxicity of glutamate receptor stimulation, and blocking these postreceptor mechanisms can be effective in protecting neurons from excitotoxicity at delayed time points.
Skier-related spinal injuries were rare and sporadic over the study period, whereas snowboarder-related spinal injuries were more frequent and more recent in occurrence.