Does colonic delivery of dexamethasone from a prodrug accelerate healing of colitis in rats without adrenal suppression?
The prodrug dexamethasone-beta-D-glucuronide delivers efficacious amounts of dexamethasone to the large intestine from lower doses than free dexamethasone.
Our findings agree with those from epidemiological studies and suggest that increases in AA intake may favorably alter the lipoprotein profile in young women.