Are elevated serum visfatin/nicotinamide phosphoribosyl-transferase levels associated with risk of postmenopausal breast cancer independently from adiponectin , leptin , and anthropometric and metabolic parameters?
Further prospective studies are needed to determine whether an elevated serum visfatin level is implicated in the etiopathogenesis of PBC or reflects changes during PBC progression and could therefore be used as a biomarker for PBC.
MiR-222 plays an important role in the tumorigenesis of CC, possibly by specifically down-regulating p27Kip1 and PTEN. Our findings suggest that miR-222 may serve as a new therapeutic target in CC.