Is overcorrection preferable for repair of degenerated articular cartilage after open-wedge high tibial osteotomy?
No significant differences were found in the ratio of cartilage repair between overcorrected and moderately corrected knees.
Our findings suggest that stretch, in isolation from other potential mediators such as pressure or hypoxia, can induce either a hyperplastic or hypertrophic response in bladder SMCs and that the cells' response is dependent on the intensity of the stretch stimulus. These observations may be relevant to the process of in vivo tissue remodeling stimulated by bladder distension or contractile dysfunction.