Does granulocyte colony-stimulating factor improve host defense to resuscitated shock and polymicrobial sepsis without provoking generalized neutrophil-mediated damage?
Our data show that G-CSF initiated at the time of resuscitation reduced the sequelae of posttrauma sepsis by increasing PMN proliferation and function without potentiating PMN-mediated lung reperfusion injury.
FOXE1 polyalanine repeat polymorphisms are associated with thyroid cancer, but only for tumours larger than 1 cm, suggesting a role in disease progression.