Are interstitial cells of Cajal involved in the afferent limb of the rectoanal inhibitory reflex?
The inhibitory innervation of the IAS and the rectoanal inhibitory reflex are mediated by NO and the rectoanal inhibitory reflex requires an intact network of ICC in the IAS. Thus both loss of nitrergic innervation and deficiency of ICC lead to impaired anal relaxation and may play an important role in rectal evacuation disorders.
Of all the patients admitted with poisoning, the treatment of nearly all the patients in good medical condition and most of the patients whose general condition was not good was completed within the Emergency Department before they were discharged from the hospital. Even when the general condition of the patients was not good at the time of presentation, it was regulated by the physicians through definitive interventions.