Is old age a contraindication for surgical treatment in acute aortic dissection?
The trend toward more conservative treatment in the elderly still occurs in our common practice even with improving surgical techniques. In our study, we suggest that pertinent surgical strategies for acute aortic dissection are necessary to improve the outcome in elderly patients.
Gonococci with ceftriaxone and cefixime MICs of 0.125-0.25 mg/L are accumulating in the UK. These MICs lie on the edge of likely responsiveness to current regimens, which need review. Possible responses include: (i) higher cephalosporin doses; (ii) multidose cephalosporin regimens; (iii) multidrug regimens; (iv) microbiologically directed treatment; or, in the future, (v) drug cycling. The practicalities of these approaches are discussed.