Does hammerhead ribozyme targeting human hypoxia inducible factor-1alpha gene effectively attenuate HeLa xenograft tumors?
It is reasonable to speculate that down-regulation of HIF-1alpha activity could be a potential mechanism useful to prevent survival or angiogenic activity of various solid tumors.
Current symptoms were related to both current exposure to inspirable dust and respirable fibre. The decrements in lung function were related to the fibre constituent of the exposure.