Is aLOX5AP expression , but not gene haplotypes , associated with obesity and insulin resistance?
ALOX5AP is present in adipose tissue, where its expression is associated with body weight and HOMA(IR), and may provide a link between adipose tissue, inflammation and insulin resistance. Investigated ALOX5AP haplotypes are not major primary risk factors for obesity and insulin resistance.
The number of cores positive for high-grade PIN was not predictive for cancer on repeat biopsy.