Does inhibition of Bcl-2 expression by a novel tumor-specific RNA interference system increase chemosensitivity to 5-fluorouracil in Hela cells?
The present study describes an efficient RNAi system for gene silencing that is specific to tumor cells using the hTERT promoter. Suppression of Bcl-2 by using this system sensitized HeLa cells to 5-fluorouracil. This system may be useful for RNAi therapy.
Although associated with it, prehypertension is not an independent predictor of organ damage in young-to-middle-aged persons of African ancestry.