Does vascular relaxation induced by C-type natriuretic peptide involve the ca2+/NO-synthase/NO pathway?
These results suggest that CNP-induced relaxation in intact aorta isolated from rats involves NO production due to [Ca2+]c increase in endothelial cells possibly through NPR-C activation expressed in these cells. The present study provides a breakthrough in the understanding of the close relationship between the vascular actions of nitric oxide and CNP.
VDR gene polymorphisms influence the skeletal response to vitamin D supplementation in healthy adolescent girls.