Do children undergoing repeated exposures for radiation therapy develop tolerance to propofol : clinical and bispectral index data?
Overall changes with time resulted from random fluctuations without a consistent trend. Combined with clinical data, Bispectral Index parameters showed that tolerance to propofol does not develop in children undergoing repeated exposures to the drug during radiation therapy.
Patients who are 35 years or older are more prone to have a failed TOL after a prior cesarean delivery.