Are constitutional CHEK2 mutations infrequent in early-onset and familial breast/ovarian cancer patients from Pakistan?
Our findings suggest that CHEK2 mutations may not contribute significantly to breast/ovarian cancer risk in Pakistani women.
Our results indicated that NDRG2 is involved in anti-apoptosis induced by EA pretreatment after focal cerebral ischemia in rats. N-Myc downstream-regulated gene 2 was involved in EA pretreatment-induced cerebral ischemic tolerance. These findings may be important for our understanding of the cellular signaling pathways induced by EA pretreatment.