Is dHA depletion in rat brain associated with impairment on spatial learning and memory?
The spatial learning and memory in adult rats are partially impaired by brain DHA depletion.
In addition to anticoagulant and anti-PLT effects, pharmacologic AT doses significantly blunted monocyte and neutrophil CD11b up regulation and neutrophil elastase release during sCPB, independent of endothelial effects. These data provide evidence for the direct anti-inflammatory activity of AT that has clinical relevance for CPB complications.