Are both IgG and IgM anti-beta2 glycoprotein I antibodies assays clinically useful to the antiphospholipid syndrome diagnosis?
Both IgG and IgM anti-beta2GPI assays were useful when clinical features of APS presented, even its standardization is ongoing. A decreased by half sensitivity of LA in PM compared with that in VT underlines the importance of adding anti-beta2GPI in PM of APS, especially IgM isotype although recent review questioned its significance.
The FHR baseline definition proposed in this article provides an extremely reproducible estimation when associated with prior training in its use.