Does high-fat nutrition reduce hepatic damage following exposure to bacterial DNA and hemorrhagic shock?
This study shows that enteral high-fat reduces IFN-gamma and decreases CpG-enhanced liver injury following hemorrhagic shock. Administration of high-fat nutrition may be an important new therapeutic strategy to reduce liver damage in a clinical setting of bacterial infection combined with hypotension.
In patients with non-resectable synchronous metastatic disease, non-surgical management of the primary tumor is a rational alternative if asymptomatic. A prospective randomized trial integrating the quality-of-life factor should be organized.