Does oral application of 1,7-dimethylxanthine ( paraxanthine ) attenuate the formation of experimental cholestatic liver fibrosis?
  Our pilot study warrants further studies of 1,7-DMX as a potential new drug to fight fibrotic processes, not just of the liver.
Circle circuit inspiratory valve leak will allow CO2-containing expirate to reverse flow into the inspiratory limb, with subsequent rebreathing during the next inspiration. This CO2 rebreathing causes imperceptible lengthening of the alveolar plateau of the capnogram and is detected only by using the CO2 spirogram (PCO2 versus volume).