Does comprehensive screening of chymotrypsin C ( CTRC ) gene in tropical calcific pancreatitis identify novel variants?
This study on a large cohort of TCP patients provides evidence of allelic heterogeneity and confirms that CTRC variants play a significant role in its pathogenesis.
Gliadin binds to CXCR3 and leads to MyD88-dependent zonulin release and increased intestinal permeability.