Do plasma amino acid levels discriminate between control subjects and mildly depressed elderly women?
We identified that the amino acids L-arginine and L-glutamic acid are risk factors for mild depression, whereas L-asparagine and the L-tyrosine/L-phenylalanine ratio are protective factors.
MCP-1/CCR2 axis accelerates NIH via its signaling in graft-extrinsic cells, particularly circulating inflammatory cells, with cells both intrinsic and extrinsic to the graft wall being critical MCP-1 producers. These findings underscore the importance of systemic treatment for anti-MCP-1/CCR2 therapies.