Is the pain level of patients affected by anxiety during transrectal prostate needle biopsy?
We found a significant relationship between trait and state anxiety levels and pain scores in patients who underwent transrectal prostate needle biopsy.
Reduced disease severity in p38γ/δ(-/-) mice was associated with lower cytokine production and anticollagen antibody responses than in controls, indicating that p38γ and p38δ are crucial regulators of inflammatory joint destruction in CIA. Our findings indicate that p38γ and p38δ are potential therapeutic targets in complex diseases, such as rheumatoid arthritis, that involve innate and adaptive immune responses.