Do cerebrospinal fluid ratios with Aβ42 predict preclinical brain β-amyloid accumulation?
These results corroborate previous findings that t-tau/Aβ
FOXF1 loss of function mutation have been so far identified in alveolar capillary dysplasia with misalignment of pulmonary veins (ACD/MPV), a lung disease different from PCH. Our data suggest the hypothesis that disruption of the FOXF1 gene enhancer could be a genetic determinant of PCH. Moreover, our findings support the idea that FOXF1 is a paternally imprinted gene.