Does iron chelation improve endothelial function in patients with coronary artery disease?
Deferoxamine improved nitric oxide-mediated, endothelium-dependent vasodilation in patients with coronary artery disease. These results suggest that iron availability contributes to impaired nitric oxide action in atherosclerosis.
Immunocompromised state and age appear to play key role in presence of the anaerobic organisms recovered from the middle ear of the patients studied.