Is pT3 urothelial carcinoma of the renal pelvis a homogeneous disease entity?
The pT3b subcategories should be regarded as true pT3, having the established features of that stage, whereas pT3a has a better prognosis.
Both MAP_Bs and YflG_Bs are functional methionine aminopeptidases in vitro and in vivo. The high expression level of map and low expression level of yflG may account for their essentiality and dispensality in B. subtilis, respectively, when cells are grown under laboratory conditions. Their difference in activity on synthetic substrates suggests that they have different protein targets in vivo.