Does alpha-interferon prevent liver collagen deposition and damage induced by prolonged bile duct obstruction in the rat?
It is concluded that interferons possess interesting beneficial effects on the liver not related to its antiviral properties but probably associated with its antifibrogenic properties.
Our results clearly show that specific proteins are required to translocate a phosphatidylcholine analogue across the ER membrane. These proteins are likely to be the flippases, which are required to translocate natural phosphatidylcholine and other phospholipids across the ER membrane. The methodology that we describe paves the way for identification of a flippase.