Do late life bipolar disorder evolving into frontotemporal dementia mimic?
Symptoms fitting the criteria for possible behavioral variant frontotemporal dementia may be present in end-stage of bipolar disorder. An alternative neurodegenerative nature seems unlikely based on repeated normal neuroimaging and the absence of clinical progression. Functional involvement of the frontal-subcortical networks might play a role.
Donor site morbidity can be a big problem especially with regard to infection which increases duration of admission and therefore cost of management.