Does testosterone promote apoptotic damage in human renal tubular cells?
These results indicate that T increases the permissiveness of proximal tubule kidney cells to apoptotic effects by triggering an apoptotic pathway involving caspase activation, Fas up-regulation, and FasL expression, thus potentially interacting with mechanisms of cell loss which have been already shown to be activated in chronic renal diseases. This is consistent with a role for T in promoting renal injury in men.
Saliva samples are as useful as urine for the identification of CMV-DNA in large use for screening programs.