Does inhibition of Protease-Epithelial Sodium Channel Signaling improve Mucociliary Function in Cystic Fibrosis Airways?
QUB-TL1 corrects aberrant CAP activities, providing a mechanism to delay or prevent the development of CF lung disease in a manner independent of CF transmembrane conductance regulator mutation.
Changes in vagal tone posture are seen on tilt in both normal and asthmatic subjects which relate to changes in ETCO(2) only in asthmatic subjects. This provides support for the hypothesis that hyper-ventilatory response to postural change in asthma is autonomically influenced.