Does alternative complement pathway deficiency ameliorate chronic smoke-induced functional and morphological ocular injury?
Taken together, these findings provide clear evidence that ocular pathology generated in CE mice is dependent on complement activation and requires the AP. Identifying animal models with RPE/BrM damage and verifying which aspects of pathology are dependent upon complement activation is essential for developing novel complement-based treatment approaches for the treatment of AMD.
Laparoscopic nephrectomy with vaginal extraction is a feasible technique in obese or overweight patients. Wound morbidity (infection, hernia) is reduced due to the small abdominal incisions.