Are p14ARF and p16INK4A , two products of the same gene , differently expressed in cervical intraepithelial neoplasia?
Overexpression of p14ARF is limited to a fraction of the p16INK4A-expressing cells and therefore it is likely that p14ARF- and p16INK4A expression are not induced by the same mechanisms. Before expression of p14ARF can be linked to invasion or invasive phenotype, larger series of (micro-) invasive squamous lesions need to be studied.
Our results support previous findings of an association between the DAT1 gene and ADHD.