Does immunohistochemical determination of p53 protein predict clinical response in advanced colorectal cancer with low thymidylate synthase expression receiving a bolus 5-fluorouracil-leucovorin combination?
p53 status measured by immunohistochemistry does not seem to be useful to identify unresponsive patients with low TS expression.
Rho/ROCK signaling is involved in GBM cell migration and proliferation, and this pathway may be linked to ERK signaling.