Does topical prazosin attenuate sensitivity to tactile stimuli in patients with complex regional pain syndrome?
Prazosin cream inhibited adrenergic axon reflex vasodilatation in healthy volunteers, and also inhibited dynamic allodynia and punctate hyperalgesia in the CRPS-affected limb of some patients. Further studies are required to assess the potential benefits of topically applied prazosin for CRPS.
One arm exercise can lead to a significant IAD in DBP. Any arm exercise should be avoided before BP measurement.