Does spatiotemporal network motif reveal the biological traits of developmental gene regulatory networks in Drosophila melanogaster?
Taken together, the proposed concept and the simulations can be used to unravel the design principle of developmental gene regulatory networks.
Vaccination with helper peptides induced both Ab responses and T-cell responses, associated with favorable clinical outcome. Such immune responses may predict favorable clinical outcome to guide combination immunotherapy. Further studies are warranted to understand mechanisms of interaction of these Abs, T-cell responses, and tumor control.