Does peritoneal dialysate affect body composition assessments using multi-frequency bioimpedance in peritoneal dialysis patients?
MFBIA measurements made in peritoneal dialysis patients with peritoneal dialysate instilled can overestimate body composition, including muscle mass, and as such potentially delay the recognition of PEW. Thus, for more accurate MFBIA in peritoneal dialysis patients, the dialysate should be drained out.
Repeated handling induces behavioral and neurochemical alterations that are absent in undisturbed animals. The persistently reduced resting time and the delayed increase in corticosterone levels indicate that mice do not habituate to handling over a 1-week period. Handling-induced modifications bias effects of gentle handling-induced sleep deprivation on sleep homeostasis, stress, glutamate receptor composition and signaling. A standardization of sleep deprivation procedures involving gentle handling will be important for unequivocally specifying how acute sleep loss affects brain function.