Does prevalence and correlate of recognized depression in U.S. nursing homes?
The prevalence of identified depression in the MEPS-NHC is lower than that previously estimated using formal diagnostic assessment techniques for threshold and subthreshold depressive states combined. Therefore, MDS-identified depression may underestimate the burden of depression. Underrecognition may be particularly acute in black or African-American residents, the oldest old, and the cognitively impaired. Further research on the relationship of MDS-identified depression and depression identified through structured diagnostic interviews in broadly representative samples of nursing home residents is needed to expand the availability of descriptive epidemiological data, to help clarify the results of research making use of MDS data, and to suggest methods for optimizing clinical and administrative data systems.
Endogenous prostaglandins, particularly prostaglandin E2, regulate CCK-, enterochromaffin-like-, somatostatin-, GIP- and enterochromaffin cells in the gastroduodenal mucosa of the rat.