Is physical frailty in older persons associated with Alzheimer disease pathology?
Physical frailty in old age is associated with Alzheimer disease pathology in older persons with and without dementia.
These results show that pre-exposure to a single high dose of apomorphine induces a long-lasting sensitization of apomorphine-induced stereotyped behavior that is context dependent. Since apomorphine directly activates dopamine receptors, these observations suggest that a mechanism located postsynaptic to dopamine neurons may be responsible for sensitization of stereotyped behavior.