Does decytabine enhance cytotoxicity induced by oxaliplatin and 5-fluorouracil in the colorectal cancer cell line Colo-205?
The observed synergism between decytabine and cytostatics is most probably related to the augmented apoptotic signal and allowed for significant (both biologically and statistically) reduction of the cytotoxic doses of cytostatics used.
[corrected] In this animal study, microscopic Mankin's scoring depicted histological improvement in cartilage of magnet group.