Is aberrant Epstein-Barr virus persistence in HIV carriers characterized by anti-Epstein-Barr virus IgA and high cellular viral loads with restricted transcription?
Asymptomatic HIV carriers show aberrant EBV persistence in the circulation, characterized by elevated, B-cell-associated EBV-DNA loads. EBV transcription is restricted, arguing for EBV gene shutdown in circulating EBV-carrying B cells. Increased IgA and IgG reactive to VCA-p18 is indicative of increased lytic EBV replication, possibly occurring at mucosal lymphoid sites but not in the circulation.
Approximately 90% of the young soccer players who began exercising under warm weather conditions were hypohydrated, while drinking ad libitum during practice did not prevent further dehydration in already dehydrated players.