Does stress-induced enhancement of mouse amygdalar synaptic plasticity depend on glucocorticoid and ß-adrenergic activity?
Acute stress changes BLA electrical properties such that subsequent LTP induction is facilitated. Both β-adrenergic and glucocorticoid receptors are involved in the development of these changes. Mineralocorticoid receptors are important for the maintenance of LTP in the BLA, irrespective of stress-induced changes in the circuit. The prolonged changes in BLA network function after stress may contribute to effective memory formation of emotional and stressful events.
Our study revealed that absolute quantification is superior to relative ratio to differentiate AD and BD from HC.