Are common coding variants of the HNF1A gene associated with multiple cardiovascular risk phenotypes in community-based samples of younger and older European-American adults : the Coronary Artery Risk Development in Young Adults Study and The Cardiovascular Health Study?
Common polymorphisms of HNF1A seem to influence multiple phenotypes related to cardiovascular risk in the general population of younger and older EA adults.
Regardless of the type of closure undertaken, there clearly is a role for newborn CBE closure without pelvic osteotomy in patients considered suitable for closure by both the pediatric urologist and orthopedic consultant. However, if there is any doubt concerning pubic diastasis width, pelvic malleability, or ease of pubic apposition, an osteotomy is highly recommended.