Is modulation of mTOR Activity by μ-Opioid Receptor Dependent upon the Association of Receptor and FK506-Binding Protein 12?
OPRM1-FKBP12 association played a key role in OPRM1-mediated mTOR activation, which could underlie the mechanisms of multiple physiological and pathological processes. Thus, our findings provide new avenue to modulating these processes.
IL-23 promotes the migration and invasion of A549 cells by inducing MMP-9 expression.