Does leptin promote human endometrial carcinoma cell proliferation by enhancing aromatase ( P450arom ) expression and estradiol formation?
Leptin is an important component of the microenvironment and stimulates endometrial carcinoma cell proliferation via enhancing P450arom expression and estradiol synthesis.
Results suggest dual users are significantly more likely to engage in risk behavior than non-users and single product users. Future interventions should consider identifying dual-users as at higher risk, and targeting multiple risk behaviors.