Do high doses of gonadotropins have no detrimental effect on in vitro fertilization outcome in normal responders?
We conclude that high doses of gonadotropins have no detrimental effect on IVF outcome in normal (intermediate) responders.
Taken together, these data indicate that transient depletion of T cells in cancer patients may disrupt the homeostatic control of cognate immunity and allow for the expansion of effector T cells with specificity against neoplastic cells. Several T cell depleting agents are clinically available and this study provides strong rationale for an examination of their efficacy in cancer patients.