Is severe left ventricular systolic dysfunction independently associated with high on-clopidogrel platelet reactivity?
An LVEF <35% was found to be independently associated with HCPR.
Endothelial degeneration and preservation of basement membrane result in an increase of string vessel formation in PD. The data may suggest a possible role for cerebral hypoperfusion in the neuronal degeneration characteristic of PD, which needs further investigation. Elevated astrocytosis in the caudate nucleus of PD cases could be associated with disruption of the blood-brain barrier in this brain region.