Do clinical characteristics of de novo pouch Crohn's disease after restorative proctocolectomy affect ileal pouch retention?
Disease characteristics of de novo pouch Crohn's disease heavily influence pouch retention. The interval from pouch construction, fistulizing disease, and disease location can be used as prognostic indicators when ileal pouch Crohn's disease is diagnosed.
Our findings do not provide any evidence for a strong role of PIK3CA mutations as a single marker in determining response to cetuximab in chemorefractory metastatic colorectal cancer.