Do elevated plasma S100B levels in high altitude hypobaric hypoxia correlate with acute mountain sickness?
Ascending to 3700 m resulted in elevated plasma S100B levels but this was not associated with AMS.
These studies demonstrate that chronic inhibition of ACE2 causes an accumulation of cardiac Ang II, which exacerbates cardiac hypertrophy and fibrosis without having any further impact on blood pressure or cardiac function.