Does halothane stimulate a Na+H+ antiporter involved in the regulation of intracellular pH in alveolar epithelial cells?
In vitro, halothane induces an intracellular alkalinization of pneumocytes II via the activation of a Na+H+ antiporter. Because acidification of these cells has been associated with alterations in the alveolar epithelial barrier, halothane might exhibit some protective effect in clinical situations, such as aspiration pneumonia.
Alpha-Glycosidase has been proved of diagnostic value for epididymal obstructive azoospermia.