Does reciprocal activation between STAT3 and miR-181b regulate the proliferation of esophageal cancer stem-like cells via the CYLD pathway?
The mutual regulation between STAT3 and miR-181b in SFCs was required for proliferation and apoptosis resistance. STAT3 and miR-181b control each other's expression in a positive feedback loop that regulates SFCs via CYLD pathway. These findings maybe is helpful for targeting ECSLC and providing approach for esophageal cancer treatments.
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