Does hypothermic machine perfusion ameliorate ischemia-reperfusion injury in rat lungs from non-heart-beating donors?
Short-term HMP improved lung tissue energy levels that decreased during warm ischemia and ameliorated ischemia-reperfusion injury with decreased production of reactive oxygen species.
These results indicate that secretion of LcrG, while observable and T3SS mediated, is not relevant for LcrG's ability to control secretion.