Are chromosomal abnormalities related to location and grade of osteoarthritis?
FISH analysis showed the presence of numerical chromosomal abnormalities in the articular cartilage of patients with OA.
Restrictive left atrial outflow adversely affects outcome after modified Norwood procedure. Abnormal pulmonary vasculature leading to insufficient pulmonary perfusion is incriminated. To improve outcome, implantation of larger size modified Blalock-Taussig or right ventricle-to-pulmonary artery shunts and routine use of postoperative mechanical assist device should be considered.