Does a host factor support retrotransposition of the TRE5-A population in Dictyostelium cells by suppressing an Argonaute protein?
The data suggest that TRE5-A amplification is controlled by a distinct pathway of the Dictyostelium RNA interference machinery that does not require RNA-dependent RNA polymerases but involves AgnC. This control is at least partially overcome by the activity of CbfA, a factor derived from the retrotransposon's host. This unusual regulation of mobile element activity most likely had a profound effect on genome evolution in D. discoideum.
We confirmed findings from previous studies that student satisfaction improves with active learning (AL). Sense of preparedness for the OSCE examination improved with AL, as well. NBME psychiatry exam scores and professed interest in psychiatry as a specialty were not different from those taught in a traditional format.