Does thyroid-stimulating hormone stimulate interleukin-6 release from 3T3-L1 adipocytes through a cAMP-protein kinase A pathway?
TSH stimulates IL-6 release from differentiated 3T3-L1 adipocytes, but not preadipocytes, by signaling through cAMP-PKA to activate IL-6 gene transcription.
WT1 mutations are a negative prognostic indicator in NK AML and may be suitable for the development of targeted therapy.