Can the prevalence of high blood drug concentrations in a population be estimated by analysing oral fluid?
Dividing the drug concentration in oral fluid by the OF/B regression coefficient gave an acceptable estimation of high blood drug concentrations in a population, and may therefore give valuable additional information on possible drug impairment, e.g. in roadside surveys of drugs and driving. If good data on the distribution of OF/B ratios are available, a Monte Carlo simulation may give better accuracy.
Greater awareness among older drivers is needed, to ensure behavioural modifications do not impair their crash protection.