Does the cellular isopeptidase T deubiquitinating enzyme regulate Kaposi 's sarcoma-associated herpesvirus K7 degradation?
IsoT1 disassembles of free ubiquitin chains to facilitate K7 degradation.
These studies establish a general inhibitory effect of EV on endothelial cell proangiogenic responses and identify a CD36-mediated mechanistic pathway through which EV inhibit MVEC migration and tube formation.