"Gloves-and-socks" melanoma: does histology make a difference?
Cutaneous melanomas in acral sites, regardless of histology, tend to be diagnosed at an advanced stage probably owing to older patient age, difficult-to-see sites, and biologic factors, leading to reduced patient survival.
Severe diastolic dysfunction is a strong predictor of adverse outcome and mortality after on-pump coronary artery bypass grafting, and this high risk is not adequately predicted by EuroSCORE and Parsonnet score. Measures of diastolic function should be included in routine preoperative risk assessment.