Do plasma levels of thrombin-antithrombin complexes predict preterm premature rupture of the fetal membranes?
Second-trimester elevated plasma TAT concentrations are predictive of subsequent PPROM. These data provide further evidence that PPROM is associated with decidual thrombin activation.
MP inhibits the fusion of monocytes into MGCs, as well as the monocyte production of pro-inflammatory cytokines, which may be an important aspect of its beneficial effect in chronic granulomatous disorders. MCG formation can be promoted by TNF-α and inhibited by TNF-α blockade.