Is near-normoglycaemic remission in African-Americans with Type 2 diabetes mellitus associated with recovery of beta cell function?
Forty-two per cent of newly diagnosed, unselected African-Americans with Type 2 diabetes, treated intensively using pharmacological agents, education and diet developed near-normoglycaemic remission. Remission was associated with a greater recovery of glucose-stimulated insulin secretion suggesting that therapies directed at promoting beta cell recovery and preservation are potentially useful approaches to the treatment of Type 2 diabetes mellitus.
Destrin is upregulated in nerve-invasive pancreatic cancer cells and its expression might be related to perineural invasiveness.