Prediction of short survival in patients with brain metastases based on three different scores: a role for 'triple-negative' status?
Although continuous research is necessary to identify patients who can be managed safely and palliated without WBRT, we feel that a model of the BSBM unfavourable group (Karnofsky performance status<80, uncontrolled primary tumour and presence of extracranial metastases) and no intent to treat systemically might form a basis for validation in other large databases. The triple-negativity criterion was not superior for predicting poor prognosis.
Lung maturation via different pathways may use different forms of collagenases for remodelling lung structure.