Does helicobacter pylori lipopolysaccharide interact with TFF1 in a pH-dependent manner?
TFF1 interacts specifically with H. pylori RF-LPS. The pH dependence of this interaction indicates that binding of H. pylori to TFF1 in the stomach could promote colonization of the mucus layer adjacent to the gastric epithelial surface.
Our results suggest that allele G of the CNR1 gene could be associated with a lower susceptibility to glioma.