Does chronic beta-adrenoceptor blockade prevent the development of beta-adrenergic subsensitivity in experimental right-sided congestive heart failure in dogs?
Excessive sympathetic stimulation may play an important role in the development of beta-receptor downregulation and beta-adrenergic subsensitivity in right heart failure.
Results underscore the potential importance of developing and testing gender specific models of chronic pain that consider the relative roles of trauma, social support, and family conflict.