Do distinct T cell signatures define subsets of patients with multiple sclerosis?
Our findings suggest that the localization of lesions within the brain vs the spinal cord in patients with MS is associated with different effector T cell responses to myelin proteins. Further investigation of the relationship between T cell effector function, antigen specificities, and lesion sites may reveal features of pathogenic pathways that are distinct to patients with different neuroinflammatory patterns.
IUET has a higher complication rate than simple intrauterine transfusion, and should be performed by well-trained specialists.