Are overexpression of B2M and loss of ALK7 expression associated with invasion , metastasis , and poor-prognosis of the pancreatic ductal adenocarcinoma?
B2M and ALK7 might be important biological markers involved in the carcinogenesis, metastasis, invasion, and prognosis of PDAC.
Tamoxifen treatment in EPS patients is associated with lower mortality and shows a trend to an increased multivariate-adjusted survival. This supports additional use of tamoxifen to treat patients with severe EPS.