Does polyinosinic-polycytidylic acid induce the expression of interferon-stimulated gene 20 in mesangial cells?
Poly (I:C) induces the expression of ISG20 in mesangial cells. ISG20 may be involved in anti-viral reactions in renal mesangial cells. TLR3, IRF3 and de novo synthesized IFN-β may mediate the poly (I:C)-induced expression of ISG20, and RIG-I may mediate ISG20 expression induced by poly (I:C)/cationic lipid complex.
Patients with depressive disorders achieved higher results than patients with depressive disorders in hypochondria, depression, hysteria, psychopathy, psychasthenia, social introversion scale and each of the five subscales of depression scale. Patients with organic depressive disorders in the test MMPI-2 tend to aggravation (unconscious exaggeration of symptoms), and elevated results on a scale of paranoia, schizophrenia, mania and masculinity-femininity.