Does estrogen impair pulmonary microvascular response to gut-derived mediators after shock conditions?
Exposure of HT-29 cells to either H/R or E2 had a deleterious effect on HMVEC monolayers. In addition, there seemed to be a synergistic effect of H/R and E2 on pulmonary endothelial injury. This study supports the findings noted in recent clinical studies suggesting E2 decreases infectious complications but may be associated with poorer outcomes if complications occur.
In contrast to general cognition, social cognition is identified by different functional (automated) activity and more localized neural structures. Only general cognition, requiring more effortful, controlled processing is related to brain function measures, particularly in frontal cortices.