Acute and chronic onset of bronchiolitis obliterans syndrome (BOS): are they different entities?
BOS likely reflects more than one process. Compared with those who had a slow linear decline in lung function, acute BOS onset was associated with acute rejection in the first 6 months, was often triggered by an acute event and had poor prognosis, with obliterative bronchiolitis (OB) the main cause of death.
Passive dorsiflexion stiffness was not strongly associated with dorsiflexion range of motion, despite the significant correlation in the non-weight-bearing condition. It must be acknowledged that passive dorsiflexion stiffness was weakly associated with dorsiflexion range of motion, although the strength of the association suggests that it may not necessarily determine dorsiflexion range of motion. Furthermore, the functional dorsiflexion limits of the ankle during weight-bearing tasks may be underestimated or misrepresented by non-weight-bearing measures of dorsiflexion range of motion. Therefore, although ankle dorsiflexion range of motion and dorsiflexion stiffness have been implicated in injury risk during weight-bearing tasks such as landings, it may be due to different mechanisms.