Do [ The effect of lactate-buffered peritoneal dialysis fluid in human peritoneal mesothelial cells function ]?
L-PDF inhibited proliferation of HPMC and increased levels of IL-8 and FN in the HPMC.
We conclude that DPP-4 is present and active in mouse and human islets, is regulated by the disease state, and that inhibition of islet DPP-4 activity can have direct effects on islet function. Inhibiting islet DPP-4 activity may therefore contribute to the insulin-secretory and glucose-lowering action of DPP-4 inhibition.