Do cochlear implant device failure secondary to cholesterol granuloma-mediated cochlear erosion?
The authors describe a unique case of a cholesterol granuloma of the middle ear and mastoid in a cochlear implant recipient causing erosion of the otic capsule and displacement of the cochlear implant electrode array into the middle ear space.
Autologous tumor lysate-pulsed DC vaccination in conjunction with TLR agonists is safe as adjuvant therapy in newly diagnosed and recurrent glioblastoma patients. Our results suggest that the mesenchymal gene expression profile may identify an immunogenic subgroup of glioblastoma that may be more responsive to immune-based therapies.