Do interactions of peptide triazole thiols with Env gp120 induce irreversible breakdown and inactivation of HIV-1 virions?
The antiviral activity of KR13 and its ability to inactivate virions prior to target cell engagement suggest that peptide triazole thiols could be highly effective in inhibiting HIV transmission across mucosal barriers and provide a novel probe to understand biochemical signals within envelope that are involved in membrane fusion.
Administration of probiotics before or after standard triple therapy may improve H. pylori eradication rates.