Does p38 MAP kinase activation mediate gamma-globin gene induction in erythroid progenitors?
This study supports a novel role for p38 MAPK in gamma-globin regulation in human erythroid progenitors.
In DPN, the predominant site of microstructural nerve alteration is at the thigh level with a strong proximal-to-distal gradient. Nerve proton spin density at the thigh level is a novel quantitative imaging biomarker of early DPN and increases with neuropathy severity.