Does inhibition of Survival Pathways MAPK and NF-kB trigger Apoptosis in Pancreatic Ductal Adenocarcinoma Cells via Suppression of Autophagy?
Here we present evidence that allows us to consider a combined therapy regimen comprising an autophagy inhibitor and a MAPK or NF-kB pathway inhibitor as a possible treatment strategy for pancreatic cancer.
Serum GGT is a strong predictor of acute coronary events in apparently healthy men from the general population, independent of other risk factors for cardiovascular disease.