Significance of P16INK4A hypermethylation gene in primary head/neck and colorectal tumors: it is a specific tissue event?
The results of this study suggest that the lack of p16 function could happen in advanced stage of SG tumors.
The use of SSEI is safe. Injection laryngoplasty is easy to perform and avoids cervical scarring. Its results are comparable to those obtained with other techniques, including laryngeal framework surgery, even if there is no standard criterion for the evaluation of voice quality. SSEI injection can reasonably be proposed as a surgical treatment for permanent unilateral vocal cord LP.