Is methylation of the TFPI2 gene frequently detected in advanced gastric carcinoma?
TFPI2 is frequently methylated in advanced gastric carcinomas.
Neonates show the expected lower content of apoB-LDL but in an inverse distribution; sdLDL being the predominant particle. This novel finding for apoB sdLDL is consistent with previous data on HPLC studies showing increased middle and small-sized LDL lipid content in neonates as compared to adults which amounts to 84% of total LDL. Comparison of the results with Lipoprint LDL (lipids) with gradient gel electrophoresis native western blot (apoB-100) suggests that neonates carry fractions of small LDL that are comparatively poor in lipids as compared with their mothers. Further studies are warranted on the issue of sdLDL in neonates.