Is up-regulation of transferrin receptor expression in hepatocytes by habitual alcohol drinking implicated in hepatic iron overload in alcoholic liver disease?
The up-regulation of TfR expression in hepatocytes is implicated in hepatic iron overload in ALD, and habitual alcohol drinking is an important factor for the induction of TfR expression.
Dopamine use in low birthweight infants may therefore be a risk factor for the development of threshold ROP. More vigilant screening of high risk infants requiring dopamine therapy for systemic hypotension may be warranted.