Is asymptomatic atopy associated with increased indoleamine 2,3-dioxygenase activity and interleukin-10 production during seasonal allergen exposure?
Enhanced systemic IDO activity as well as increased systemic levels of IL-10 may contribute to the containment of allergic T cell responses and could be involved in the maintenance of a state of clinical unresponsiveness.
BTG2 may be a modulator of cell survival and differentiation and could help to protect against cell death by inhibition of necrosis and/or apoptotic signalling pathways.