Are allopurinol dose and duration of use nephroprotective in the elderly?
Higher allopurinol dose is independently protective against incident renal failure in the elderly allopurinol users. A longer duration of allopurinol use may be associated with lower risk of incident renal failure. Potential mechanisms of these effects need to be examined.
SNAIL is probably associated with the initiation and progression of cervical cancer and seems to be a promising candidate marker in early stage cervical cancer.