Does danning tablets attenuate α-naphthylisothiocyanate-induced cholestasis by modulating the expression of transporters and metabolic enzymes?
DNts might promote bile acid and bilirubin elimination by regulating the expressions of hepatic and renal transporters as well as hepatic metabolic enzymes.
This study indicates that STAT signaling may be an important mediator of biological treatments, such as CD154 gene therapy, and that early STAT1 activation may predict response to this novel treatment.