307 Is Catheter Diagnostic Cerebral Angiography Still Essential for Patients With Spontaneous Perimesencephalic Subarachnoid Hemorrhage and Negative Computed Tomography Angiogram?
This study shows that CT angiography, even when read as "negative" for cases assumed to have a benign perimesencephalic pattern of subarachnoid hemorrhage, is still insufficient to exclude underlying pathology as the source of hemorrhage. This study showed a "false-negative" CT angiogram read of 9.3%. Although false negatives are very low, indicating a high negative predictive value of CT angiograms, its dependability in excluding underlying pathology is still not 100% when the question involves a life-threatening pathology as a ruptured cerebral aneurysm. Digital subtraction angiogram still remains the gold standard for confirming or excluding underlying pathology for the perimesencephalic subarachnoid hemorrhage.
Inhibition of NO synthesis enhanced myocardial stunning transmurally in conscious dogs, potentially independent of its effects on blood flow.