Is axon reflex-related hyperemia induced by short local heating reproducible?
Single-point LDF is a reproducible technique of assessing AR flare on volar surface of the forearm when the heating period is reduced to 5 min and the recording sites are fixed. Using this new protocol, short-heating LTH has a potential to be used to evaluate the effects of acute physical or chemical interventions between two short-heating LTH tests to further explore the pathophysiological meaning of heating-induced AR flare.
These results indicate that sub-100 nm sized TiO(2) treatment under ultraviolet A irradiation induces apoptotic cell death through reactive oxygen species-mediated upregulation of the death receptor, Fas, and activation of the preapoptotic protein, Bax. Elucidating the molecular mechanisms by which nanosized particles induce activation of cell death signaling pathways would be critical for the development of prevention strategies to minimize the cytotoxicity of nanomaterials.