Is baseline T cell reactivity in multiple sclerosis correlated to efficacy of interferon-beta?
Our results suggest that the level of T cell proliferation in whole blood predicts efficacy of IFN-beta in MS.
We induced renal crystal deposition in mice with metabolic syndrome using a high fat diet and ethylene glycol. Increases in luminal mineral and lipid density, and proinflammatory adipocytokines and macrophages facilitated renal crystal formation in mice with metabolic syndrome.