Is [ The expression of fibroblast activation protein-α in primary breast cancer associated with poor prognosis ]?
High expression of FAP-α in primary breast tumors is associated with a bad prognosis in patients whose lesions are negative for both estrogen and progesterone receptors. Expression of TGF-β1 is positively related with FAP-α expression in primary breast tumors.
• MMP-7 is present in detectable amounts in the urine of patients with bladder cancer. Its concentrations are significantly elevated in patients with metastatic disease. • Determination of urinary matrilysin level could help to detect bladder cancer metastasis, and may therefore provide a more reliable prognosis and influence therapy decisions.