Does diclofenac inhibit tumor necrosis factor-α-induced nuclear factor-κB activation causing synergistic hepatocyte apoptosis?
Together, our data suggest a model whereby diclofenac-mediated stress signaling suppresses TNF-α-induced survival signaling routes and sensitizes cells to apoptosis.
The findings of this study suggest that a history of stroke in the recipient may lend to a lower SAS and that a low SAS is associated with ICU admission following transplant, leading to higher hospital costs.