Implantable ventricular assist devices: is it time to introduce them in Canada?
Limited application in a limited number of centres with collection of all data is justifiable at this stage.
Our findings suggest that in addition to serving as mechanisms for adaptation, receptor downregulation and desensitization can play a critical role in temporal information processing. Furthermore, engineering metaphors such as the ones described here could prove to be invaluable in understanding the design principles of biological systems.