Are basophil activation and sulphidoleukotriene determination useful tests for monitoring patients with peach allergy receiving sublingual immunotherapy with a Pru p 3-enriched peach extract?
SLIT with a Pru p 3 quantified peach extract is clinically effective and leads to an increase in basophil activation and sulphidoleukotriene production following stimulation with rPru p3 and peach peel in the first months of treatment.
Our study identifies increased activation of Wnt pathways in the arteries of patients with ESRD, which is significantly correlated with the incidence of vascular calcification. These findings support Wnt pathways as a potential target for future therapy of vascular calcification in CKD.