Do insulin-lowering agents inhibit synthesis of testosterone in ovaries of DHEA-induced PCOS rats?
Insulin-lowering agents affected ovarian tissue by inhibiting testosterone biosynthesis in vivo.
Our data shows that miR-21, miR-192 and miR-200 could be used as new diagnostic markers for pancreatic cancer. A dynamics of these miRNAs could serve as a prognostic marker in patients after cancer removal. Futher prospective studies with newly-onset diabetic patients with no signs of malignancy will be needed to validate if suggested miRNAs could be used as early markers as well.