Does serum oxidative stress level correlate with clinical parameters in chronic systolic heart failure patients?
In chronic systolic HF patients, high serum OS levels correlate with advanced disease and known markers of poor prognosis.
The dip in response of the heart to ISO stimulation during the animal's active period is absent in adult SHRs. This may result from disruption to the circadian clock mechanism, which depresses the cycling of nNOS expression.