Does transplantation of endothelial progenitor cells alleviate renal interstitial fibrosis in a mouse model of unilateral ureteral obstruction?
The reduction of PTC density and up-regulation of HIF-1alpha are the important mechanisms of interstitial fibrosis in UUO mice. BM-EPCs transplantation may increase the number of capillary density and alleviate the development of renal fibrosis in obstructive nephropathy in mice.
We found that NES was not associated with BMI or AHI severity. The findings show that NES is primarily an eating disorder, rather than a sleep disorder, and that there is an association between NES and depressed mood.