Can reinforcement-based interventions to reduce drug use successfully be adapted to routine opioid maintenance treatment?
The intervention was not effective compared to routine treatment. Additional features might be necessary to achieve an effect, e.g. a higher frequency of urine sampling or use of other reinforcers. It has to be further investigated how interventions which have been proven effective in experimental studies can successfully be adapted to routine care conditions.
The effects of unsaturated fatty acid are attributed to the overstimulation of epimorphin signaling and suggest the epimorphin antagonist as a possible therapeutic agent for acne and hyperkeratotic skin disease.