Is a higher degree of methylation of the HPV 16 E6 gene associated with a lower likelihood of being diagnosed with cervical intraepithelial neoplasia?
Results suggested that CpG methylation is independently involved in the biology of HPV 16 as well as in the development of higher grades of CIN.
Breast-feeding is of public health significance in preventing chronic disease. There is a small but consistent effect of premature weaning from breast milk in increasing later-life chronic disease risk. Risk exposure in the Australian population is substantial. Approximately 90 % of current 35-45-year-olds were weaned from breast-feeding by 6 months of age. Encouraging greater duration and exclusivity of breast-feeding is a potential avenue for reducing future chronic disease burden and health system costs.