Does cytokeratin 20 expression identify a subtype of pancreatic adenocarcinoma with decreased overall survival?
CK 20 expression defines a subtype of pancreas cancer with important biologic properties. When present, CK 20 expression is an early event in pancreatic carcinogenesis identifiable in precursor lesions. Further studies to identify the underlying genetic changes associated with this altered developmental pathway are warranted.
These data demonstrate that platelet eNOS activity is potentiated after statin treatment in humans in parallel with experimental studies.