Is anti-inflammatory activity of Chios mastic gum associated with inhibition of TNF-alpha induced oxidative stress?
We suggest that mastic gum inhibits PKC which attenuates production of superoxide and H2O2 by NADPH oxidases. This antioxidant property may have direct implication to the anti-inflammatory activity of the Chios mastic gum.
Ethanol enhanced proenkephalin promoter activity and potentiated isoproterenol-stimulated promoter activity through a cAMP-independent pathway.