Is basal ganglia pathology in ALS associated with neuropsychological deficits?
We demonstrate correlations between basal ganglia measures and structure-specific neuropsychological performance and a gradient of incremental basal ganglia pathology across the ALS-ALS-FTD spectrum, suggesting that the degree of subcortical gray matter pathology in C9orf72-negative ALS is closely associated with neuropsychological changes.
The prevalence of meeting the PA standard among on-reserve First Nations youth is very low. More research is needed to identify independent risk indicators of being physically inactive.