Does hypercholesterolemia increase myocardial oxidative and nitrosative stress thereby leading to cardiac dysfunction in apoB-100 transgenic mice?
We conclude that hypercholesterolemia but not hypertriglyceridemia leads to increased formation of superoxide and peroxynitrite, and thereby results in cardiac dysfunction in hearts of human apoB100 transgenic mice.
The anticancer effects of celecoxib on NPC cell lines results from inducing apoptosis and cell cycle arrest, which may be partly mediated through the STAT3 pathway.