Do designed azolopyridinium salts block protective antigen pores in vitro and protect cells from anthrax toxin?
These results strongly argue in favor of a transport of lethal factor through the PA63-channel and suggest that the heterocycles used in this study could represent attractive candidates for development of novel therapeutic strategies against anthrax.
Waist circumference as a predictor of future Type 2 diabetes is supported by the finding that they share common genetic influences.