Do cardiac myocytes produce interleukin-6 in culture and in viable border zone of reperfused infarctions?
Isolated cardiac myocytes produce IL-6 mRNA in response to several cytokines as well as postischemic cardiac lymph. In addition to its production by inflammatory cells, we demonstrate that IL-6 mRNA is induced in myocytes in the viable border zone of a myocardial infarct. The potential roles of IL-6 in cardiac myocytes in an infarct border are discussed.
Chromosomal imbalances, together with histopathological factors, may help to predict outcome in breast cancer patients.