Does toll-like receptor 2 enhance ZO-1-associated intestinal epithelial barrier integrity via protein kinase C?
The present study provides evidence that PKC is an essential component of the TLR2 signaling pathway with the physiologic consequence of directly enhancing intestinal epithelial integrity through translocation of ZO-1 on activation.
The non-dipping profile of CHD patients and increased mortality were related to a lack of antihypertensive drug administration at bedtime.