Does inhibition of CYP2E1 lead to decreased malondialdehyde-acetaldehyde adduct formation in VL-17A cells under chronic alcohol exposure?
CYP2E1-mediated metabolism of ethanol leads to increased AA-, MDA-, and MAA-adduct formation in liver cells which may aggravate liver injury.
Genetic variation at the WLS and CCDC170/ESR1 loci were found to be significantly associated with BMD adjusted for only age and gender at the genome-wide level in this meta-analysis.