Does adolescent exposure to methylphenidate alter the activity of rat midbrain dopamine neurons?
Adolescent exposure to methylphenidate induces neuronal changes associated with increased addiction liability in rats.
p27(kip1) gene therapy mediated by adenovirus vector has a significant inhibitory effect on esophageal carcinoma in vivo. Up-regulated p27(kip1) expression and down-regulated survivin expression may be its important mechanisms.