Does epidermal growth factor promote invasiveness of pancreatic cancer cells through NF-kappaB-mediated proteinase productions?
Our findings indicated that NF-kappaB-mediated MMP-9 and uPA induction was responsible for EGF-induced invasiveness in these pancreatic cancer cell lines and implicate that such anti-NF-kappaB therapy as the use of NF-kappaB inhibitors may contribute to the reduction of invasiveness of pancreatic cancer.
Adiposity and systemic inflammation unrelated to OSA severity, modulate MMP-9 levels in Greek children.