Do genetic and epigenetic changes in p21 and p21B correlate with resistance to doxorubicin or mitomycin and 5-fluorouracil in locally advanced breast cancer?
Our findings do not suggest that genetic or epigenetic disturbances in p21 or p21B cause resistance to doxorubicin or mitomycin/5-fluorouracil in breast cancer. Future studies should assess potential associations between these novel polymorphisms and breast cancer risk.
LVHT-patients with AF deserve special care because they have a worse prognosis than LVHT-patients without AF.