Does a small-molecule inhibitor targeting the mitotic spindle checkpoint impair the growth of uterine leiomyosarcoma?
Our results show that dysregulated centrosome function and spindle assembly are a robust feature of ULMS that can be targeted to slow its growth both in vitro and in vivo. These observations identify novel directions that can be potentially used to improve clinical outcomes for this disease.
A single application of radial SWT is an effective treatment for chronic patellar tendinopathy.