Does depletion of brain serotonin following intra-raphe injections of 5,7-dihydroxytryptamine alter d-amphetamine self-administration across different schedule and access conditions?
These results provide no evidence that reducing 5-HT function alters the primary reinforcing effects of self-administered amphetamine. The increase in self-administration of a low dose of amphetamine observed in experiment 1 probably involves some other process such as increased resistance to extinction.
The ACS model may improve abdominal surgical efficiency and quality. Our study results echoed the benefits of the implementation of the ACS model shown in North America.