Do mast cells mediate acid-induced augmentation of opossum esophageal blood flow via histamine and nitric oxide?
These findings provide evidence that mast cell-derived histamine, acting through an NO-dependent mechanism, plays a central role in the response of the esophageal microcirculation to luminal acid.
These results demonstrate how a genomewide approach to the complex phenotype of human tuberculosis can identify novel targets for further research.