Describing gerontological nursing: an academic exercise or prerequisite for progress?
Gerontological practice requires an accessible consensus view and description to support its development. Practising nurses developed such a view and its utility has been seen in the development of best practice statements. Relevance to clinical practice. The description and principles of gerontological nursing can be used to guide nursing practice, practice development and research.
Our findings indicate that GM3 synthase silencing suppressed lung metastasis in murine breast cancer cells. The molecular mechanism that underlies GM3 synthase mediated migration and invasion was inhibition of the phosphoinositide-3 kinase/Akt pathway. The findings suggest that GM3 synthase may be of value as a therapeutic target in breast cancer.