Toll-like receptors in the uterus, cervix, and placenta: is pregnancy an immunosuppressed state?
These findings suggest that the innate immune system is a dynamic system during gestation. The concept of immunosuppression during pregnancy appears to be valid in the placenta only in regard to TLR expression. Research is warranted to determine whether the upregulation in the uterus and cervix during pregnancy is associated with an increased likelihood of responding to a pathogen or serve as a protective mechanism or both.
Medicare and Medicaid beneficiaries are both at an increased risk of a PLOS. This study was not designed to identify the potential causes of a PLOS. Data from prospectively collected bariatric registries might aid surgeons in assessing the risk/benefit ratio of surgical interventions in groups regarded as high risk.