Is the course of gastric cancer following surgery associated with genetic variations of the interleukin-1 receptor antagonist and interleukin-1β?
Genetic variations in the IL-1β and IL-1RN genes influence disease progression in gastric cancer. Screening for these genetic variations might help to stratify therapies for gastric cancer patients in the future.
The results found in this study show a definite trend towards poorer accommodative and vergence function with the use of contact lenses in comparison to glasses. This downward trend, though not statistically significant in accommodative function (lower PRA values and less lens amplitude of accommodation) might suggest that temporal insufficiency in the accommodation process could be occurring while contact lenses are used, thereby possibly creating a lag in accommodation to reduce associated overconvergence. This would be manifested in more esophoric values being found in the vergence function. The higher accommodative lags found in this study with SCL could indicate that prolonged use of SCL in near tasks may provoke a continuous hyperopic retinal defocus, a risk factor for the onset and progression of myopia, as indicated in numerous studies.