Are biological characteristics of growth hormone-producing pituitary adenomas different according to responsiveness to thyrotropin-releasing hormone?
The present data suggest that the responsiveness of serum GH level to TRH reflects significant tumor biological characteristics.
This study does not provide evidence to support recommendations concerning the ideal age for hypospadias repair. In the absence of evidence of a benefit of early surgery, anesthesia-related risk factors must be considered when operating in very early infancy. Large, prospective studies, measuring surgical and psychological outcome with similar instruments to those presented may reveal whether there is a true ideal age for hypospadias surgery.