Do t cells from presensitized donors fail to cause graft-versus-host disease in a pig-to-mouse xenotransplantation model?
These results demonstrate that porcine T-cell function is severely impaired in the xenogeneic murine microenvironment.
These results show that KIR expression is restricted to CD56+/CD3- true NK cell lymphomas originating from the nose, gut, and skin, as well as in a subset of extranodal T cell lymphomas originating from the small intestine, which possessed a cytotoxic phenotype. Thus, the presence of KIR on NK/T cell lymphomas seems to mimic the distribution of KIR found on NK and T cells in normal lymphoid tissue.