Is endogenous inhibition of somatic pain impaired in girls with irritable bowel syndrome compared with healthy girls?
This study found that young girls with IBS have deficient endogenous pain inhibition compared to healthy girls, which is consistent with the literature on adults. This information can facilitate clinicians in identification of risk factors for onset/maintenance of IBS and other chronic pain conditions.
Because AKAP9 was not previously linked to AD risk, this study indicates a potential new disease mechanism.