Does erythropoietin modulate imbalance of matrix metalloproteinase-2 and tissue inhibitor of metalloproteinase-2 in doxorubicin-induced cardiotoxicity?
The present study suggests that EPO can exert a cardioprotective effect on DOX-induced cardiotoxicity which may be associated with improving MMP-2/TIMP-2 imbalance.
In our study, RF ablation extends the therapeutic envelope, is an effective local treatment of liver metastases and improves life expectancy.