Is suppression of circulating interleukin-6 concentrations associated with decreased endothelial activation in rheumatoid arthritis?
Our results suggest that suppression of circulating IL-6 concentrations attenuates atherogenesis in active RA.
These data have led to the hypothesis that the suppressed expression of ISGF-3 proteins and consequent reduction in responsiveness to endogenous IFN likely are an early event in skin carcinogenesis.