Does a computational model predict adjunctive pharmacotherapy for cardiac safety via selective inhibition of the late cardiac Na current?
Our computer modeling approach based on experimental data, yields results that suggest that selective inhibition of I
Hippocampal volume was affected by early life stress but recovered in adulthood which corresponded to normal adult neurogenesis. Synaptic plasticity, however, exhibited a delayed impairment. The modulation of synaptic plasticity by early life stress might contribute to affective dysfunction in adulthood.