Does inactivation of NMD increase viability of sup45 nonsense mutants in Saccharomyces cerevisiae?
This is the first demonstration that sup45 mutations do not only change translation fidelity but also acts by causing a change in mRNA stability.
This exploratory analysis suggests that, in patients who require stenting of a large coronary artery, use of a clinical risk score may identify those patients for whom DES use may confer a clinical advantage over BMS, beyond lower restenosis rates.