Does peroxisome proliferator-activated receptor-γ activation induce 11β-hydroxysteroid dehydrogenase type 1 activity in human alternative macrophages?
Our data identify a positive cross-talk between PPARγ and GR in human M2 macrophages via the induction of 11β-HSD1 expression and activity.
This study represents one of the few attempts to date to evaluate the impact of phenol intake on oxidative damage. Flavonoids intake must be promoted to reduce the negative health effects of oxidative stress in elderly people.