Does induction of P450 1A by 3-methylcholanthrene protect mice from aristolochic acid-I-induced acute renal injury?
These results demonstrated that the induction of hepatic P450 1A1/2 protected against AAI-induced kidney injury through faster in vivo clearance of AAI and suggested an important role for hepatic P450s in the detoxification of AAI-induced renal injury.
These results indicate that expression of ephrinB2 in hematopoietic cells is regulated by interaction with particular stromal cells, and ephrinB2-EphB4 interaction modulates the migration and colonization of the hematopoietic cells in the local stromal microenvironment.