Is superiority of biphasic over monophasic defibrillation shocks attributable to less intracellular calcium transient heterogeneity?
The greater efficacy of BW shocks is directly related to their less heterogeneous effects on shock-induced SR Ca release and Ca(i) transients. Less heterogeneous Ca(i) transients reduces the probability of Ca(i) sinkhole formation, thereby preventing the post-shock reinitiation of ventricular fibrillation.
Mortality of incident and new subsequent cases of NMSC was similar and thus did not explain the reduced mortality of BCC patients.