Does the Use of Hypothermic Circulatory Arrest During Heart Transplantation Worsen Posttransplant Survival?
The need for HCA during heart transplantation is rare but, when required, it is frequently a life-saving adjunct to cardiopulmonary bypass. However, patients who require HCA have higher rates of postoperative complications. Risk factors for needing HCA during transplantation include congenital heart disease and more than one prior sternotomies.
These data suggest PF-4 derived octapeptide exerts antiinflammatory effects of experimental arthritis in mice.