Is macrophage activation syndrome in patients with systemic juvenile idiopathic arthritis associated with MUNC13-4 polymorphisms?
The data suggest an association between MUNC13-4 polymorphisms and macrophage activation syndrome in patients with systemic JIA.
All together, our data demonstrate that angiotensin II inhibits HUVEC motility by reducing NO availability. Such reduction is due to an angiotensin II type 1 receptor-dependent increment in intracellular ROS generation.