Does serum thyrotrophin at baseline predict the natural course of subclinical hyperthyroidism?
Thyrotrophin predicts overt hyperthyroidism in asymptomatic individuals with subclinical hyperthyroidism. Patients with TSH < 0·10 mU/l have a higher risk of progressing to hyperthyroidism than those with TSH 0·10-0·39 mU/l.
Clinicians treating adolescents should be aware of the potential for serotonin syndrome.