Is obesity associated with emotional and behavioural problems in children?
Childhood obesity is associated with emotional and behavioural problems from a very young age. Obese boys are at particular risk. Further research is required to examine effect modifiers and mediating factors in these associations. Recognition and response to these mental health problems should be a goal of pediatric obesity interventions and policies.
These data reveal a novel role for cytosolic DNA sensor pathways in bone in the setting of autoimmune disease. We demonstrate the requirement of an intact STING pathway for bone formation in this model, a finding that may have relevance to autoimmune diseases in which DNA plays a pathogenic role. Identification of pathways linking innate immunity and bone could reveal novel targets for the treatment of bone abnormalities in autoimmune diseases. This article is protected by copyright. All rights reserved.