Is the body mass index a less-sensitive tool for detecting cases with obesity-associated co-morbidities in short stature subjects?
The prevalence of obesity-associated co-morbidities is higher in subjects with short stature compared to those without it. The proficiency of BMI as a diagnostic tool is poor in short stature subjects. This problem is not resolved by decreasing BMI thresholds used to define overweight.
This study suggests that the texture of medial tibial trabecular bone measured from plain radiographs is related to the risk of KJR: with increasing FD(MEAN) (the overall measure of bone texture roughness) the risk of KJR was reduced, independent of other clinical predictors of joint replacement. Tibial trabecular bone texture may be a useful marker of disease progression and a target of therapy in OA.