Does dNA methylome profiling of human tissues identify global and tissue-specific methylation patterns?
This genome-wide methylation profiling study identified tissue-specific differentially methylated regions in 17 human somatic tissues. Many of the genes corresponding to these differentially methylated regions contribute to tissue-specific functions. Future studies may use these data as a reference to identify markers of perturbed differentiation and disease-related pathogenic mechanisms.
The plasma ET-1 level may be a predictor of all-cause death in a healthy population.