Platelet aggregation according to body mass index in patients undergoing coronary stenting: should clopidogrel loading-dose be weight adjusted?
These data suggest that overweight patients may need a higher loading-dose of clopidogrel and/or an adjunct antithrombotic treatment to adequately inhibit platelet aggregation early after CS.
TNF played important roles in the pathogenesis of myocardial injury following burns, its level was correlated with the severity of myocardial injury. TNF levels in E group was much lower that in NE group, suggesting that prompt escharectomy could reduce the production and release of inflammatory cytokines, and lessen the myocardial injury induced by uncontrolled inflammatory response.