Are innate IgG molecules and innate B cells expressed by immunoglobulin constant heavy G chain ( Fcγ ) genetic marker genes involved in the 'allergic march ' of IgE sensitization in children?
The IGHG*bfn haplotype (B*(bfn) cells) and increased innate IgG2*n levels are predictive factors for IgE sensitization in childhood. IGHG genes can be assessed for prognostic and preventive purposes in clinical care.
These results suggest that the presence of an animal can significantly increase positive social behaviors among children with ASD.