Is tissue transglutaminase autoantibody the best for diagnosing celiac disease in children of developing countries?
tTG antibody is a highly sensitive and specific serologic marker. Being technically simpler and due to its high concordance with EMA, it can be used as an alternative to EMA in developing countries like India.
This study extends the known phenotype of the C9orf72 expansion in both age at onset and movement disorder symptoms. We propose a revised clinico-genetic algorithm for the investigation of HD phenocopy patients based on these data.