Is jAK2V617F mutation common in old patients with polycythemia vera and essential thrombocythemia?
JAK2V617F mutation is more common in old than in young patients with MPD. Older patients have an higher allele burden.
Cardiac arrest patients receiving CPR have higher circulating atrial natriuretic peptide concentrations than healthy subjects. High serum atrial natriuretic peptide concentrations may antagonize the vasopressor response to epinephrine. Blocking this effect of atrial natriuretic peptide may improve outcomes in patients suffering cardiac arrest.