Are peritoneal microvascular endothelial function and the microinflammatory state associated with baseline peritoneal transport characteristics in uremic patients?
Uremic patients display differences in peritoneal microvascular endothelial function and microinflammatory states before peritoneal dialysis. Patients of the high transport group have higher MVD, increased expression of endothelial function markers (VEGF and eNOS), and the microinflammatory marker (IL-6). These observations are closely related to high baseline peritoneal transport.
In conclusion, routine testing for MGUS before transplantation is not prognostic nor a contraindication to transplant, and therefore, it is not recommended.