Does [ Thrombosis induced by homocysteine depend on platelet aggregation or heparin cofactor 's antithrombin activity ]?
There is no correlation between Hcy and the "ADP passway" of platelet aggregation. Thrombosis induced by Hcy does not depend on heparin cofactor's antithrombin activity either.
These data indicate that applying transdermal verapamil gel to the penile shaft results in a small amount of systemic absorption but the gel does not infiltrate the tunica albuginea. Based on these findings the use of transdermal verapamil for Peyronie's disease has no scientific basis.