Are routine radiographs needed in the first year after lumbar spinal fusions?
Routine radiographs seem to have limited utility in the early postoperative period after instrumented LSF and may place patients with normal H/E at an increased risk of undergoing unnecessary diagnostic studies. Patients with abnormal H/E were more likely to undergo more extensive testing leading to additional treatment being prescribed regardless of the interpretation of the radiographs.
Repeated inhalation exposures of neonatal and juvenile mice to endotoxin and cockroach allergen increased the pulmonary inflammatory and systemic immune responses in a synergistic manner and enhanced alveolar remodelling in the developing lung. These data underscore the importance of evaluating the effect of multiple, concurrent environmental exposures, and of using an experimental model that incorporates clinically relevant timing and route of exposures.