Are c-Jun , pc-Jun , and p27 differently expressed in oral leukoplakias in smokers and never-smokers?
Smoking habits may be linked to the expression of proteins directly associated with cell cycle progression.
These results demonstrate that Mas can hetero-oligomerize with the AT1 receptor and by so doing inhibit the actions of angiotensin II. This is a novel demonstration that a G-protein-coupled receptor acts as a physiological antagonist of a previously characterized receptor. Consequently, the AT1-Mas complex could be of great importance as a target for pharmacological intervention in cardiovascular diseases.