Is vDR expression on circulating endothelial progenitor cells in dialysis patients modulated by 25 ( OH ) D serum levels and calcitriol therapy?
Our study demonstrates the presence of VDR on EPCs. In our dialysis patients, the parameters studied on both CD34+/CD133+/KDR+ and CD34+/CD133-/KDR+ cells, in particular VDR expression, seem to be influenced by uremia-related factors, including anemia, inflammation, diabetes, 25(OH)D serum levels and calcitriol therapy.
The CRP and Hcy levels may affect the development and progression of abnormal HRR in PCOS.