Does toll-like receptor 2 regulate intestinal inflammation by controlling integrity of the enteric nervous system?
In mice, TLR2 signaling regulates intestinal inflammation by controlling ENS structure and neurochemical coding, along with intestinal neuromuscular function. These findings provide information as to how defective TLR2 signaling in the ENS affects inflammatory bowel disease phenotype in humans.
Like laparoscopy, HALS is associated with less postoperative ileus and necessitates less NGT decompression than does open surgery.