Does remodeling of actin cytoskeleton in mouse periosteal cells under mechanical loading induce periosteal cell proliferation during bone formation?
These results suggest that the structural change in cell shape via disorganization and remodeling of the actin cytoskeleton played an important role in the mechanical loading-dependent proliferation of cells in the periosteum during bone formation.
As a first step toward understanding the different molecular conditions of beating and non-beating hESC-CMs, we sought to study their differential expression patterns and discuss their relevance to in vivo functioning in cardiac injury repair. Thus, the results of this study could provide further evidence supporting a cardiac regenerative approach using an optimized cell source derived from hESCs.