Are rASSF7 and RASSF8 proteins predictive factors for development and metastasis in malignant thyroid neoplasms?
RASSF7 and RASSF8 expression was increased in PTC and MTC compared to NTG, and this may be linked to the development and progression of thyroid carcinoma. In addition, these proteins were correlated with more advanced tumor stages, tumor size, and metastasis.
Our findings dispute a role of iron overload in the pathogenesis of type 2 diabetes.