Do stress markers and anesthetic technique predict delirium in the elderly?
The development of PD depends more on postoperative stress than intraoperative stress or anesthetic.
Berberine impairs muscle metabolism by two novel mechanisms. It impairs mitochonidrial function stimulating the expression of atrogin-1 without affecting phosphorylation of forkhead transcription factors. The increase in atrogin-1 not only stimulated protein degradation but also suppressed protein synthesis, causing muscle atrophy.