Is lens gap junctional coupling modulated by connexin identity and the locus of gene expression?
Lens size and fiber cell coupling conductance depended on which connexin was expressed on the Cx50 gene locus, whereas homeostasis of central fibers and normal gap junction gating were maintained when either connexin was expressed. The authors conclude that the roles of lens gap junction channels depend not only on the primary sequence of the expressed connexin, but also on the gene locus that expresses the connexin.
A higher number of screens in a child's bedroom was associated with higher adiposity, more total screen time and lower sleep efficiency. Having a TV in the bedroom appears to be the type of screen presence associated with higher levels of adiposity. Given the popularity of screens among children, these findings are increasingly relevant to health promotion strategies.