Do microRNA-98 mediated microvascular hyperpermeability during burn shock phase via inhibiting FIH-1?
The findings of the present study suggest severe microvascular permeability due to burns; and the underlying mechanism bases on the promotion of miR-98 level to the extent that it activated HIF-1 gene expression, resulting in junction-associated protein deficiency.
Our results give support to the hypothesis that the D3 receptor could play a role in emotional behaviors.