Does absence of cytochrome P450 2A5 enhance alcohol-induced liver injury in mice?
These results suggest that cytochrome P450 2A5 protects against ethanol-induced oxidative liver injury.
Genistein's effects are concentration-dependent in both cell lines. Lower concentrations elicit proliferative effects on UtLM cells only; whereas, higher concentrations alter morphology, inhibit proliferation, and increase caspase activity and apoptosis in both cell types, with the latter two effects being more extensive in UtSMCs.