Is resistance of retinal ganglion cells to an increase in intraocular pressure immune-dependent?
In rats of different strains, a similar increase in IOP results in differing amounts of RGC loss. This disparity was found to correlate with immune potency. These findings may explain why patients with glaucoma experience different degrees of visual loss after pressure reduction, even when the severity of the disease at the time of diagnosis is similar. The results have far-reaching prognostic and therapeutic implications.
This study confirms the need for vision screenings and appropriate follow-up through pediatric eye examinations. Furthermore, this study stresses the importance of community collaboration to improve access of care and adequate penetration within communities.