Are paraoxonase 1 arylesterase activity and mass reduced and inversely related to C-reactive protein in patients on either standard or home nocturnal hemodialysis?
PON1 is reduced in HNHD patients compared to HC subjects, independent of the concentration of HDL cholesterol. Within subjects on HD, the combination of increased CRP and reduced PON1 may identify subjects at a high risk for cardiovascular complications.
For those born in the first half of the twentieth century, the association between low birth weight and adult hypertension is due to poor fetal growth and not due to preterm birth.