Is impairment in cognitive inhibition in the acute phase of major depression irreversible?
The results show that impairment in cognitive inhibition is long lasting when present in the acute phase of recurrent depression. Impaired cognitive inhibition might be an irreversible vulnerability marker for recurrent depression.
Galectin-1 is a luteotrophic factor whose binding is inhibited by α2,6-sialylation in the human CL during luteolysis. ST6GAL1 and galectin-3 expression is increased during luteolysis and associated with a loss of progesterone synthesis. Luteotrophic hormones differentially regulate galectin-1 and galectin-3/α2,6-sialylation in granulosa lutein cells, suggesting a novel galectin switch regulated by luteotrophic stimuli during luteolysis and luteal rescue.