Does a divergent myeloid dendritic cell response at virus set-point predict disease outcome in SIV-infected rhesus macaques?
mDC recruitment to and death within inflamed lymph nodes may contribute to disease progression in SIV infection, whereas mobilization without increased recruitment to lymph nodes may promote disease control.
This study demonstrates that an initial obese environment triggers a detrimental state in ASCs that is not completely recovered after weight loss.