Do neural tube defects lead to structural alterations in the human bladder?
The structural alterations of the bladder found in this study may suggest the existence of functional alterations in the bladder of anencephalic human fetuses.
Although further details on the molecular function of AQP1 or 4 related to tumorigenesis remain to be elucidated, our results suggest a potential role of AQP1 or 4 as novel therapeutic targets for the management of lung cancer.