Do marginal integrity of direct and indirect castings for implant abutments?
With CMAs, it is possible to make an exact duplicate of the abutment. This permits the laboratory to make castings on duplicate abutments with greater precision than can be obtained using the indirect technique. Direct fabrication of castings resulted in smaller marginal gaps, which in turn allows a better marginal seal and improved retention of castings.
The current study provides experimental evidence for an epigenetical, extracellular matrix-induced loss of p53 function, which lead to a potent chemotherapy resistance showing accordance with the clinical experience.