Does preprandial single oral dose of sitagliptin affect circulating ghrelin and gastrin levels in normal subjects?
Preprandial oral dose of sitagliptin does not affect circulating ghrelin, gastrin, insulin, and glucose concentrations in normal subjects. Decreased ghrelin and increased gastrin and insulin levels occurred only after meal loading. These results support the theory that sitagliptin might not cause appetite-enhanced body weight gain and insulin-induced hypoglycemia.
Psychotic-like experiences may increase the risk of suicidal problems among adolescents.