Is pulmonary MnSOD nitrated following hepatic ischemia-reperfusion?
Pulmonary MnSOD is both nitrated and inactivated following hepatic I/R and is associated with acute lung injury. These findings suggest that MnSOD incapacitance may contribute to I/R-induced lung injury and provide a therapeutic target in attenuating multisystem injury following hepatic I/R.
The results of this study suggest that CDS detects graft-threatening lesions, that a velocity ratio of 2.0 or greater is the most highly predictive parameter, and that revision of grafts with stenoses identified with CDS prolongs patency.