Does epidermal growth factor-induced cytoprotection in human intestinal cells involve intracellular calcium signaling?
Taken together, these data strongly suggest that the cytoprotective effects of EGF may involve Ca(2+) signaling.
Early, and to a lesser extent late treatment, with a low but not a high dose of everolimus is effective in reducing proteinuria in nephrotic rats. The mechanism may be via nephrin/podocin protection.