Is chemotaxis of human keratocytes increased by platelet-derived growth factor-BB , epidermal growth factor , transforming growth factor-alpha , acidic fibroblast growth factor , insulin-like growth factor-I , and transforming growth factor-beta?
These in vitro results demonstrate that PDGF-BB, EGF, TGF-alpha, aFGF, IGF-I, and TGF-beta 1 increase keratocyte chemotaxis, and they may play an important role in the early recruitment of keratocytes to the corneal wound site in vivo.
In-person training for physician educators on the use of a web-based alcohol curriculum can increase teaching confidence and practices. Although the web is frequently used for dissemination, in-person training may be preferable to effect widespread teaching of clinical skills like alcohol screening and brief intervention.