S100B protein expression in the heart of deceased individuals by overdose: a new forensic marker?
Our preliminary data show that the S100B protein accumulates in injured cardiomyocytes during drug-related sudden death. Given the near absence of S100B protein in the heart of subjects who died from causes other than drug overdose, S100B immunopositivity may be used as a new ancillary screening tool for the postmortem diagnosis of overdose-related cardiac death.
We propose that segmental Budd-Chiari syndrome can be a valid terminology for asymptomatic patients with segmental hepatic vein occlusion most likely developing as a sequela of subclinical Budd-Chiari syndrome. Acquaintance of practicing radiologists to this phenomenon may be highly useful in the prevention of the diagnostic confusion and potentially unnecessary interventions.