General and specific cognitive deficits in schizophrenia: Goliath defeats David?
The schizophrenia cognitive deficit is largely generalized across performance domains, with small, direct effects of diagnostic group confined to selected domains. This generalized deficit sometimes has been seen as a function of the psychometric limitations of traditional cognitive test batteries. Alternatively, it may be a fundamental manifestation of schizophrenia, with similarly general neurobiological underpinnings.
PAMAM dendrimer-induced leukocyte PCA depends on particle size, charge and density of surface groups.