Is the XX sex chromosome complement in mice associated with increased spontaneous lupus compared with XY?
These data show that the XX sex chromosome complement, compared with XY(-), is associated with accelerated spontaneous lupus.
The diverse drug binding methods employed here are well suited to detect specific binding of LCM to CRMP-2 in the micromolar range, yet the results obtained were all negative. Results of this study suggest that LCM does not specifically bind to CRMP-2.