Do mesenchymal stem cells attenuate hypoxic pulmonary vasoconstriction by a paracrine mechanism?
We conclude that acute hypoxia induces HPV and that MSC-conditioned media acutely attenuates this effect. Thus, in addition to a direct contribution to vessel remodeling in chronic hypoxia, MSCs may acutely protect and attenuate hypoxic pulmonary vasoreactivity through a paracrine mechanism.
The shaving of the incision site immediately before spinal surgery may increase the rate of postoperative infection.