Is urine output on ICU entry associated with hospital mortality in unselected critically ill patients?
UO obtained on ICU entry is an independent predictor of mortality irrespective of diuretic use. It would be interesting to examine whether strategies to increase UO would improve clinical outcome.
Excimer laser transepithelial photoablation induced significantly less keratocyte loss than manual epithelial debridement; however, photoablation was followed by a more intense inflammatory response and a greater increase in backscattering of light (haze) that was associated with increased keratocyte activation and myofibroblast transformation. Most important, the magnitude of corneal wound repair and the development and duration of corneal haze increased proportionally with increasing stromal photoablation depth (i.e., the volume of stromal tissue removal) but were unrelated to depth of initial keratocyte loss.