Do reactive oxygen species regulate prosurvival ERK1/2 signaling and bFGF expression in gliosis within the retina?
The novel finding of this study that ROS contribute to a prosurvival signaling pathway in retinal Müller cell gliosis indicates that some degree of caution should be used when considering antioxidants as therapeutics.
Low baseline serum iron indicators are associated with increased mortality and hospitalization in MHD patients independent of hemoglobin level, EPO and iron doses, indicators of nutrition and inflammation, and comorbid conditions. Clinical trials to examine the role of iron administration in improving morbidity and mortality by increasing serum iron levels in MHD patients are required.