Does physiological oestradiol administration change the biological to immunological ratio of LH in serum from post-menopausal women?
The treatment of post-menopausal women with 50-mg E2 subcutaneous implants produces physiological premenopausal E2 levels for at least 6 months. There is no change in the B:I ratio of LH using either the RIA or IRMA during chronic E2 treatment.
Baseline expression of ISGs in PBMCs from HCV/HIV-coinfected patients influence the response to peginterferon/ribavirin therapy, regardless of IL28B genotypes. PBMC specimens can reliably be used for evaluating ISGs expression in clinical practice.