Do dihydrotestosterone and leptin regulate gonadotropin-releasing hormone ( GnRH ) expression and secretion in human GnRH-secreting neuroblasts?
Our results suggest that androgens (adequate hormonal status) could have a positive effect on GnRH neuronal activity by synergizing with leptin (adequate energy status) in the regulatory mechanisms required for reproductive and sexual fitness.
These data suggest that discount rates vary with the preferred drug of abuse, and that high discount rates should be considered in the development of substance abuse prevention and treatment efforts.