Does diffusion tensor MRI correlate with executive dysfunction in patients with ischaemic leukoaraiosis?
Diffusion tensor measurements correlate better with cognition than conventional MRI measures. They may be useful in monitoring disease progression and as a surrogate marker for treatment trials. The findings support the role of white matter damage and disruption of white matter connections in the pathogenesis of cognitive impairment in cerebral small vessel disease.
Increased PAPP-A activity may be involved in the inflammation and tissue remodelling that occurs in allergic rhinitis.