Do surface microgrooves and acid etching on titanium substrata alter various cell behaviors of cultured human gingival fibroblasts?
This study indicates that surface microgrooves 60 mum in width and 10 mum in depth, and further acid etching on Ti substrata trigger the proliferation and alter the expression of both genes and proteins in cultured human gingival fibroblasts.
Taken together with our recent findings that birth itself regulates the initiation of sensory map formation in the somatosensory and visual systems, these results support the idea that the birth of pups actively regulates the anatomical and functional development of the sensory system.