Is use of a structured palliative care summary in patients with established cancer associated with reduced hospital admissions by out-of-hours general practitioners in Grampian?
Availability of a structured palliative care plan can aid decision making in the out-of-hours period and prevent unplanned hospital admissions.
TLC could serve as a low-cost tool for determining both a patient's risk of OI and when to initiate prophylaxis in resource-constrained settings. PPV, NPV, sensitivity, and specificity maximally aggregated at TLC <1400 cells/mm3 for CD4 <200 cell/mm3 and TLC <1700 cells/mm3 for CD4 <350 cells/mm3. Selection of appropriate TLC cutoffs for prophylaxis administration should be made on a regional basis depending on OI incidence, antimicrobial resistance patterns, and availability of the antimicrobials.