Is lower ankle-brachial index associated with poor sleep quality in patients with essential hypertension?
Poor sleep quality was independently associated with lower ABI in patients with essential hypertension. The results may provide new insight related to the interaction between sleep quality and blood pressure.
The helical zipper domain of Ac 1, 2-CTD has no equivalent in other proteins of known structure. Sequence analysis suggests the domain is a common motif in all members of the 1,2-CTD family. Complexes with catechol and 4-methylcatechol are the highest resolution complex structures to date of an intradiol dioxygenase. Furthermore, they confirm several observations seen in 3,4-PCDs, including ligand displacement upon binding exogenous ligands. The structures presented here are the first of a new family of intradiol dioxygenases.