Is apoptosis initiated in human keratinocytes exposed to signalling factors from microbeam irradiated cells?
This study shows that similar bystander signalling pathways leading to apoptosis are induced following microbeam irradiation and following medium transfer. This demonstrates that the mechanisms involved are common across different radiation qualities and conditions and indicates that they may be relevant in vivo.
RARC appears to be well tolerated, independent of comorbid risk factors such as age, BMI, RCRI and ASA score.