Does 4-Aminopyridine restore impaired hypoxic pulmonary vasoconstriction in endotoxemic mice?
This study demonstrates that lipopolysaccharide-induced pulmonary vascular hyporesponsiveness to hypoxia can be restored by 4-AP in murine endotoxemia and, thus, may be a new therapeutic approach to treat patients with hypoxemia due to impaired HPV.
Elevated RDW is independently associated with advanced fibrosis in NAFLD.