Does hDL mimetic peptide CER-522 treatment regress left ventricular diastolic dysfunction in cholesterol-fed rabbits?
CER-522 improves LVDD in rabbits, with reductions of LV macrophage accumulation, cardiomyocyte apoptosis, coronary atherosclerosis and remodelling.
The association between CRP concentration and CAC score differed according to HDL-C levels.