Are mR findings of collateral circulation more accurate measures of hemodynamic significance than arm-leg blood pressure gradient after repair of coarctation of the aorta?
The arm-leg blood pressure gradient is not a reliable indicator of hemodynamic significance of restenosis in patients with prior repair of CoA. Direct visualization of collateral vessels by MRA and percent increase in flow from proximal to distal descending thoracic aorta are reliable indicators of hemodynamic significance.
The use of homeopathic antidiarrheal agents for childhood diarrhea is a minimally adopted innovation. Lack of correlation between adoption and individual innovativeness may suggest that this innovation is unlikely to be adopted in the future without intervention. Current barriers to adoption reveal that a stronger evidence base, and efforts to increase awareness and experiential knowledge, would be necessary to increase adoption. The results reported in this paper are discussed in the context of current theories on knowledge translation in medicine.