Is desflurane Consumption During Automated Closed-circuit Delivery Higher Than When a Conventional Anesthesia Machine is Used With a Simple Vaporizer-O₂-N₂O Fresh Gas Flow Sequence?
Agent consumption with an automated closed-circuit anesthesia machine is higher than with a conventional anesthesia machine when the latter is used with a specific vaporizer-FGF sequence. Agent consumption during automated delivery might be further reduced by optimizing the algorithm(s) that manages the initial FGF or by tolerating some N₂ in the circuit to minimize the need for intermittent flushing.
The activation of TNFα mediated Rho kinase signaling pathway can significantly promote smooth muscle cell proliferation, and Rosuvastatin can not only inhibit this pathway but also the induced proliferation.