Is suppression of cell migration promoted by miR-944 through targeting of SIAH1 and PTP4A1 in breast cancer cells?
Our results pointed out that miR-944 is a novel upstream negative regulator of SIAH1 and PTP4A1 genes and provided for the first time evidence for its functional role in migration and invasion of breast cancer cells. They also suggest that miR-944 restoration may represent a potential strategy for breast cancer therapy.
Serum beta-hCG by itself cannot predict whether a tubal ectopic pregnancy is likely to be ruptured; there is no safe lower limit in hCG titer below which ruptured ectopic is not seen.