Is dependence of the minimal clinically important improvement on the baseline value a consequence of floor and ceiling effects and not different expectations by patients?
Variation in MCII by baseline values is because of floor and ceiling effects rather than expectations of particular patients.
Patients with T1,2,3N3M0 disease can be divided into prognostically different subgroups according to the number of metastatic lymph nodes in the axilla and the nodal ratio; in this way, different patient subgroups may be offered different treatment strategies.