Does granulocyte colony-stimulating factor prophylaxis improve survival and inflammation in a two-hit model of hemorrhage and sepsis?
Hemorrhage (first hit) sensitized the host for a second hit of polymicrobial PCI independent of the timing. G-CSF prophylaxis improved survival and clearance of microbes and reduced the proinflammatory chemokine macrophage inflammatory protein-2 in the lung.
Vertical displacement of the syringe pump alters the flow due to a change of line IP, and blood pressure can be affected by pump movement during NE infusion.