Can rescaling dose of dialysis to body surface area in the HEMO study explain the different responses to dose in women versus men?
When normalized to body surface area rather than V, the dose of dialysis in women in the HEMO Study was substantially lower than in men. The lowest surface-area-normalized dose was received by women randomized to the conventional dose arm, possibly explaining the sex-specific response to dialysis dose. Results are consistent with the hypothesis that when dialysis dose is expressed as Kt/V, women, due to their lower V/SA ratio, require a higher amount than men.
Preoperative lumbar epidural morphine facilitates postoperative analgesia and improves initial postoperative ventilatory performance.