Does the prokineticin receptor agonist Bv8 decrease IL-10 and IL-4 production in mice splenocytes by activating prokineticin receptor-1?
These findings indicate that Bv8/prokineticin-1 is a novel modulator of lymphoid functions, and may be a suitable target for new immunopharmacological strategies.
The footprint peak time behaviour of different patients with chronic stroke reflected their hemiparetic gait pattern. The slower patients had prolonged footprint peak times on the non-affected side (NS) and shorter values on the lateral footprint on the affected side (AS). The increased gait velocity and the FAP scores decreased the footprint peak times on both sides, especially on the NS. The rehabilitation increased the gait velocity with 18.2%, decreased the duration of the mid-foot and forefoot peak times on the NS and the lateral mid-foot peak times on the AS. A detailed analysis of the individual gait performance allows more accurate assessment of the potential for gait recovery.