Do crk adaptor proteins act as key signaling integrators for breast tumorigenesis?
These data highlight the physiological importance of Crk proteins in regulating growth of aggressive basal breast cancer cells and identify Crk-dependent signaling networks as promising therapeutic targets.
Compared with non-frail patients without polypharmacy, frail elderly patients with polypharmacy belong to a high-risk group and should receive an immediate geriatric assessment and treatment including long-term planning by the Mobile Geriatric Team.