Is genotype Ser413/Ser of PAI-2 polymorphism Ser413/Cys associated with anti-phospholipid syndrome and systemic lupus erythematosus in a familial case : comparison with healthy controls?
Our data indicate that this family did not follow the Mendelian inheritance pattern. The Ser(413)/Ser genotype demonstrated in 60% of the affected members (3/5) of this family might increase the risk for autoimmune syndromes such as APS or SLE.
Results of the study suggest that the sutureless sublay technique is safe and effective in the treatment of ventral abdominal hernia, especially in small and medium defects.