Does tissue endothelin-converting enzyme activity correlate with cardiovascular risk factors in coronary artery disease?
These data demonstrate, for the first time, that vascular ECE activity is (1) inversely correlated with serum LDL levels and blood pressure and (2) positively associated with fibrinogen in human vascular tissue. Hence, ECE-1 activity may modulate cardiovascular risk in patients with coronary artery disease.
This study suggests that the functional promoter polymorphism at IL-10 may play a role in the development of endometriosis.