Does insulin enhance nitric oxide production in trabecular meshwork cells via de novo pathway for tetrahydrobiopterin synthesis?
Insulin increases NO production in TM cells via de novo synthetic pathway for BH(4) synthesis. Insulin could be involved in the regulation of trabecular outflow by enhancing NO production in TM cells.
Sleep disturbances are associated with an increased risk of cesarean delivery and preterm birth throughout pregnancy. Obstetric care providers should advise women with childbearing age to practice healthy sleep hygiene measures.