Does a signature of aberrant immune responsiveness identify myocardial dysfunction in rheumatoid arthritis?
The major finding of this study was that aberrant systemic immune responsiveness is associated with advanced myocardial dysfunction in patients with RA. The unique information added by the immune response score concerning the likelihood of LVDD warrants future longitudinal studies of its value in predicting future deterioration in myocardial function.
To our knowledge, the present paper provides the first evidence of MCM in animal models.