Is expression of toll-like receptor TLR-2 , TLR-3 , TLR-4 and TLR-9 increased in placentas from patients with preeclampsia?
TLR-2, -3, -4 and -9 expressions are increased in preeclamptic placentas. However, more studies are required to determine the role of TLRs in pregnancy immunology and to establish its relationship with preeclampsia.
Our study demonstrates that the expression of miR-30b-5p is down-regulated in cardiac hypertrophy, and restoration of its function inhibits the expression of CaMKIIδ, suggesting that miR-30b-5p may act as a hypertrophic suppressor.