Does transcription Factor Runx2 promote Aortic Fibrosis and Stiffness in Type 2 Diabetes Mellitus?
In conclusion, this study highlights Runx2 as a previously unrecognized inducer of vascular fibrosis in the setting of diabetes mellitus, promoting arterial stiffness irrespective of calcification.
Ventilation by external high-frequency oscillations increases cardiac index and improves tissue perfusion. The increased pumping of the heart is probably caused by changes of the intracardiac pressure-volume relationship. The Hayek Oscillator may have distinct cardiovascular benefits as ventilatory assistance in postoperative cardiac surgical patients.