Is binding of human monoclonal IgG rheumatoid factors to Fc influenced by carbohydrate?
This suggests that conformational changes in the polypeptide chain induced by the carbohydrate are responsible for the observed binding patterns.
Administration of KOR agonist protects the muscle flap microcirculation from I/R injury, which can be abolished by concomitant KOR antagonist administration. The KOR agonist-induced protection from ischemia reperfusion injury may be related to decreased expression of adhesion molecule ICAM-1.