Does pooling-based genome-wide association study implicate gamma-glutamyltransferase 1 ( GGT1 ) gene in pancreatic carcinogenesis?
Our results suggest that common variation in the GGT1 gene may affect the risk of pancreatic cancer. .
The finding that a significant fraction of clonogenic neural stem cells lack the established markers CD133 and CD15, and that some of these cells may be dormant or slow-cycling, has implications for approaches to identify and isolate neural stem cells and brain cancer stem cells. Our data also suggest the possibility that CD133 may be specifically down-regulated during G0/G1, and this should be considered when this marker is used to identify and isolate other tissue and cancer stem cells.