Does extracellular chaperonin 10 augment apoptotic cell death induced by 5-fluorouracil in human colon cancer cells?
Our findings indicate that concurrent treatment with cpn10 and 5-FU warrants further investigation in an effort to overcome 5-FU resistance and enhance the efficacy of 5-FU therapy for colon cancer.
An early, single dose of PTX dramatically reduced brain inflammation and apoptosis for up to 16 h post-injury.