Symptoms of depression in late luteal phase dysphoric disorder: a variant of mood disorder?
LLPD is likely to represent a variant of a depressive disorder, where premenstrual psychobiological changes seem to exacerbate mild depressive symptoms and signs to which LLPD women are otherwise predisposed. This hypothesis opens new perspectives for prevention and of even treatment for LLPD. Further longitudinal studies with larger populations and evaluation of hormonal changes are needed to confirm these data.
iNOS and EP3-6 expression are strongly correlated in gravid and misoprostol-treated, nongravid myometrium.