Are c-Type Natriuretic Peptide ( CNP ) levels altered in boys with Klinefelter syndrome?
In contrast to plasma NTproBNP, CNP production and clearance are increased in boys with Klinefelter syndrome. Together these findings argue against an interaction between BNP with CNP in the growth plate. Why CNP peptide levels are altered in Klinefelter syndrome remains to be explored.
The sample size was small, and the effects of medication on the results could not be excluded.