Does reflectance speckle of retinal nerve fiber layer reveal axonal activity?
Fixation stops axonal activity; treatments with either lower temperature or microtubule depolymerization are known to decrease axonal transport. The results obtained in this study suggest that temporal change of RNFL speckle reveals structural change due to axonal activity. Assessment of RNFL reflectance speckle may offer a new means of evaluating axonal function.
Excess body fat maintained after the seventh decade decreases life expectancy but appears to be less lethal in women.