Does purinergic signaling underlie CFTR control of human airway epithelial cell volume?
Loss of CFTR and CFTR-driven autocrine ATP signaling may underlie defective cell volume regulation and dysregulated ion, water, and acid-base transport in CF airway epithelia.
S/D treatment efficiently releases PDGF-AB, TGF-beta1, and EGF from nonactivated apheresis PCs and may be of interest to prepare virally inactivated allogeneic growth factors for clinical and cell culture applications.