Is it convenient in a screening programme for prostate tumour to do biopsy in people with PSA between 3 and 3.9 ng/ml?
Doing biopsy on patients with PSA between 3 and 3.9 ng/ml and with rectal exploration and suspect TR prostate echography does not permit a remarkable increase in diagnosis of prostate tumour (4.4%). Doing prostate biopsy on patients with PSA between 3 and 3.9 ng/ml and pathological PSA free/PSA total relation, allows a more considerable increase in diagnosis of prostate tumour with Gleason score greater than 7 even if it does not permit a remarkable increase in positive diagnosis (4.62%).
LDL selectively enhances the synthesis of specific PG and HA by mesangial cells. Such effects may contribute to the expansion of the mesangial matrix and modify cell-matrix interactions in lipid-induced renal damage.