Does ent-11α-Hydroxy-15-oxo-kaur-16-en-19-oic-acid inhibit Growth of Human Lung Cancer A549 Cells by Arresting Cell Cycle and Triggering Apoptosis?
5F could inhibit the proliferation of A549 cells by arresting the cells in G2 phase and by inducing mitochondrial-mediated apoptosis.
From our data, prodigiosin is an attractive compound that turns the profile of high-level survivin expression in hepatocellular carcinoma cells into that of normal cells and may provide a novel approach to the hepatocellular carcinoma-targeted therapy.