Does acetaminophen attenuate lipid peroxidation in children undergoing cardiopulmonary bypass?
Cardiopulmonary bypass in children is associated with hemolysis and lipid peroxidation. Acetaminophen attenuated the increase in plasma isofuran concentrations. Future studies are needed to establish whether other therapies that attenuate or prevent the effects of free hemoglobin result in more effective inhibition of lipid peroxidation in patients undergoing cardiopulmonary bypass.
A decrease in let-7i may be related to poor clinical outcomes in patients with DCM.