Does persistence of disseminated tumor cells after neoadjuvant treatment for locally advanced breast cancer predict poor survival?
Presence of DTCs after NACT indicated high risk for relapse and death, irrespective of the DTC-status before treatment. The results supports the potential use of DTC analysis as a monitoring tool during follow up, for selection of patients to secondary treatment intervention within clinical trials.
The anti-CD4 antibody can block the binding of gp120 and CD4 positive T cells in a low concentration, but it did not block V3 peptide-induced sperm head agglutination. Therefore, V3 peptide-induced sperm head agglutination may not occur through a CD4 receptor.