Are all people with diabetes and cardiovascular risk factors or microvascular complications at very high risk?
In this population, the rate of major CV events was lower than expected. This prediction model could help clinicians identify people with DM at higher CV risk and support them in achieving goals of physical activity and HbA1c.
GSPE (concentration of higher than 20 microg/ml) could inhibit HepG2 cell survival, and in HepG2 cells, endogenous apoA-I was significantly suppressed following 24h of exposure to high concentrations of glucose. Meanwhile GSPE could promote expression of apoA-L dose dependently at mRNA level when its concentration was lower than 10 microg/ml.