Does recombinant human granulocyte colony-stimulating factor attenuate inflammatory responses in septic patients with neutropenia?
Administration of rhG-CSF attenuates inflammatory responses without inducing tissue injury in septic patients with neutropenia.
The hyaluronan binding sites of ITI are located in the heavy chains of this molecule. ITI is concentrated in the pericellular environment of granulosa cells through hyaluronan-binding. The altered amount of hyaluronan and ITI in the preovulatory ovaries may contribute to their important clinical characteristics including cumulus oocyte complex expansion.