Does dietary calcium exacerbate phytate inhibition of zinc absorption by women from conventional diets?
In healthy women consuming 1-d menus of ordinary foods (some fortified with calcium), dietary phytate reduces zinc absorption, but calcium does not impair zinc absorption, regardless of whether dietary phytate is low or high.
All these results suggest that GC- II is the key site for Sp1 binding and increase of Sp1 binding activity rather than protein levels contributes to the induction of p16(INK4a) expression during cell aging.