Are insulin-like growth factors II exon 9 and E-cadherin-Pml I but not myeloperoxidase promoter-463 , urokinase-ApaL I nor xeroderma pigmentosum polymorphisms associated with higher susceptibility to leiomyoma?
IGF2*A allele and CDH1*C allele were correlated with leiomyoma susceptibility, which may be associated with leiomyoma development. MPO, urokinase, XPA and XPD polymorphisms are not related to leiomyoma susceptibilities.
We demonstrate that ATV can control over-expression of proinflammatory endothelial TLR2 protein and TLR2-mediated endothelial activation. The mechanism involves casein kinase 2 and SP1 phosphorylation. ATV effects on endothelial cell TLR2 are comparable to those of laminar blood flow and might therefore also be atheroprotective.