Does inactivation of Hippo Pathway be Significantly Associated with Poor Prognosis in Hepatocellular Carcinoma?
Inactivation of the Hippo pathway in HCC is significantly associated with poor prognosis.
These results indicate that the combination of Rh2 and paclitaxel has an effect on growth inhibition that is greater and synergistic, as demonstrated in a cultured LNCaP cell line. Conversely combining Rh2 with mitoxantrone appears to elicit no benefit. Therefore, combination therapy using chemotherapy and Rh2 requires further investigation.