Does infection with a periodontal pathogen induce procoagulant effects in human aortic endothelial cells?
Taken together these data demonstrate for the first time that infection with a periodontal pathogen induces procoagulant responses in HAEC.
Taken together our experimentation supports the hypothesis that Akt/mTOR/S6K cascade may contribute to metformin alleviating effect. The present work while highlighting metformin anti-oxidant characteristics, concludes that Akt/mTOR signaling might be central to the drug's alleviating effects.