Does transforming growth factor beta 1 regulate tissue inhibitor of metalloproteinases-1 expression in differentiated human articular chondrocytes?
Our findings suggest that TGF beta 1 has a protective effect on the extracellular matrix of human articular chondrocytes.
CAB shows antagonistic activity to PPARgamma and can block the adipocyte differentiation, indicating it may be of potential use as a lead therapeutic compound for obesity.