Does cardiac Myocyte KLF5 regulate Ppara Expression and Cardiac Function?
Cardiac myocyte KLF5 is a transcriptional regulator of Ppara and cardiac energetics.
We could not confirm our hypothesis that most or all patients with azathioprine-induced pancreatitis were pancreatic autoantibody positive. The prevalence of pancreatic autoantibodies in the Crohn's disease patients in our group was lower than in previous reports.This study does not support an association between pancreatic autoantibodies and azathioprine-induced pancreatitis in Crohn's disease. However, this association should not be definitively excluded and larger, preferably prospective, studies are needed.