Does disruption of caveolae block ischemic preconditioning-mediated S-nitrosylation of mitochondrial proteins?
Altogether these results suggest that caveolae transduce eNOS/NO/SNO cardioprotective signaling in the heart.
The unmethylated 5' flank of the H19 gene adopts an unusual and maternal-specific chromatin conformation in somatic cells and regulates enhancer-promoter communications, thereby providing an explanation for its role in manifesting the repressed state of the maternally inherited Igf2 allele.