Do overweight and obese children have low bone mass and area for their weight?
In overweight and obese boys and girls there is a mismatch between body weight and bone development during growth: their bone mass and bone area are low for their body weight.
Our data indicate that over-activated Notch-1 significantly protects BGC-823 cells from TNFalpha-induced apoptosis, and this effect is mediated, at least in part, by decreasing activation of caspase-3 independent of NF-kappaB.