Does nS4A protein as a marker of HCV history suggest that different HCV genotypes originally evolved from genotype 1b?
These observations indicate that NS4A protein of different HCV genotypes originally evolved from NS4A protein of genotype 1 subtype 1b, which in turn indicate that HCV genotype 1 subtype 1b established itself earlier in human population and all other known genotypes evolved later as a result of mutations in HCV genotype 1b. These results were further confirmed through phylogenetic analysis by constructing phylogenetic tree using NS4A protein as a phylogenetic marker.
admission HG is associated with greater mortality rates up to 5 years after stroke but does not influence the survival of TIA patients.