Does frailty attenuate the Impact of Metformin on Reducing Mortality in Older Adults with Type 2 Diabetes?
Our study suggests that metformin could potentially promote longevity via preventing frailty in older adults with type 2 diabetes.
These findings provide important information that myocardial AMPK activation by metformin following I/R sets into motion events, including eNOS activation, which ultimately lead to cardioprotection.