Does bone alkaline phosphatase serum level predict the response to antiandrogen withdrawal?
Lower serum levels of BAP seems to correlate with a better response to antiandrogen withdrawal. Moreover, a level of BAP higher than 50 ng/ml would predict strongly the absence of response.
We conclude that the need for amputation and multiple operations is determined by the injury itself and that immediate decompression is only required for the usual clinical signs of compartment syndrome. Selective decompression may actually preserve tissue and decrease the need for eventual amputation because fasciotomy can lead to soft tissue dessication by exposing viable tissue.