Does perioperative ketorolac increase post-tonsillectomy hemorrhage in adults but not children?
Ketorolac can be used safely in children, but is associated with a five-fold increased bleeding risk in adults.
PDGF-BB enhances proliferation by suppressing PDCD4 expression by up-regulation of miRNA-21 in human orbital fibroblasts. These results suggest that PDGF-BB stimulates cell proliferation through microRNA-21-mediated PDCD4 down-regulation, leading to the development of TAO.