Are large decreases in standardized uptake values after definitive radiation associated with better survival of patients with locally advanced non-small cell lung cancer?
The post-RT SUV(max) in both the PT and the LNs was a predictor of survival-specifically, the higher the residual SUV(max) after RT, the poorer the OS and DFS; and the greater the decrease in SUV(max) in the lesion with the highest SUV(max) at diagnosis, the longer the OS and DFS. This information should help to identify patients who are at high risk of recurrence and for whom additional treatments can be designed accordingly.
In our model system, we found that diamagnetic levitation led to changes that are very similar to those caused by real- [e.g. on board the International Space Station (ISS)] or mechanically-simulated microgravity [e.g. using a Random Positioning Machine (RPM)]. These changes decoupled meristematic cell proliferation from ribosome biogenesis, and altered auxin polar transport.