Are 11β Hydroxysteroid dehydrogenase type 2 and dietary acid load independently associated with blood pressure in healthy children and adolescents?
A lower 11βHSD2 activity and higher dietary acid load may independently contribute to higher systolic BP in healthy children.
Our results demonstrated the reduction of Kv4.2 expression might contribute to the development of post-ischemic seizures and long-term increased seizure susceptibility after ischemia. The mechanisms underlying post-stroke seizures and epilepsy is unknown so far. The down-regulation of IA channels may explained the abnormal neuronal hyperexcitability responsible for the seizure development after ischemic stroke.