Does use of discharge-worksheet enhance compliance with evidence-based myocardial infarction care?
A simple "Acute MI Discharge Worksheet" was associated with better adherence and documentation of evidence-based post MI care and be a useful component to improve post MI care.
These data provide the first evidence for functional retargeting of PDE5 from one compartment to another, revealing a role for natriuretic peptide-derived cGMP hydrolysis by this esterase in diseased heart myocardium. Retargeting likely affects the pathophysiological consequence and the therapeutic impact of PDE5 modulation in heart disease.