Does recombinant human interleukin-6 induce hepatocyte growth factor production in cancer patients?
In humans, rhIL-6 administration resulted in an increase in serum HGF levels.
FCT is effective in women<36 and ≥36 years. The balance between FPR and DR is more favourable in women<36 years with comparable OAPR. Although FPR increases with increasing maternal age, performance of FCT in AMA women is more effective than screening based on maternal age alone. Lowering the cut-off to 1:100 in AMA women is suggested to improve screening performance. Routinely offering diagnostic testing to AMA women as a screening policy for the detection of DS seems not reasonable.