Does epidermal growth factor inhibit the growth of TE8 esophageal cancer cells through the activation of STAT1?
The findings herein suggest that EGF inhibits the growth of some esophageal cancer cells that overexpress EGFR and that the activation of STAT1 constitutes a critical event which is required for the inhibition of growth by EGF.
The results of this study provide the first large-scale, generalizable evidence for the validity of dentists' subjective assessment of caries risk.