Are measures of atherosclerotic burden associated with clinically manifest cardiovascular disease in type 2 diabetes : a European cross-sectional study?
Measures of atherosclerotic burden are associated with clinically manifest CVD in subjects with T2D. In addition, vascular changes that are not directly related to known metabolic risk factors are important in the development of both atherosclerosis and CVD in T2D. A better understanding of the mechanisms involved is crucial for enabling better identification of CVD risk in T2D.
Longitudinal studies are needed to clarify the direction of causality between vitamin B6 and depressive symptoms.