Does local MicroRNA Modulation Using a Novel Anti-miR-21-Eluting Stent Effectively prevent Experimental In-Stent Restenosis?
This study demonstrates the efficacy of an anti-miR-coated stent for the reduction of ISR.
After CPB, thrombin generation in neonatal plasma was augmented by the addition of 4F-PCCs. The peak amount and rate of thrombin generation were enhanced in all conditions, whereas the lag time was shortened more with FEIBA. Our findings suggest that the use of 4F-PCCs containing activated FVII may be an effective adjunct to the initial transfusion of platelets and cryoprecipitate to augment coagulation and control bleeding in neonates after CPB.