Does trimetazidine potentiate the effects of exercise training in patients with ischemic cardiomyopathy referred for cardiac rehabilitation?
The addition of TMZ to ET determined greater improvements in functional capacity, left ventricular ejection fraction, and endothelium-dependent dilation than TMZ or ET given alone. No differences between improvements after TMZ and E as compared with controls were observed.
These findings provide a better understanding of oxidative stress-mediated lung tumorigenesis.