Does suppression of PTRF alleviate the polymicrobial sepsis induced by cecal ligation and puncture in mice?
PTRF is a crucial regulator of TLR4 signaling in the development of sepsis.
LR of WB resulted in lower hemostatic potential of FFP in conjunction with depletion of MPs and coagulation factors. Longer WB hold time did not significantly affect the hemostatic potential of FFP as measured by TEG. Acceptable hemostatic quality was maintained for all FFP processing conditions studied.