Does knockdown of ERK/Slug signals sensitize HL-60 Leukemia cells to Cytarabine via upregulation of PUMA?
The chemosensitiveness of HL-60 cells to Cyt were relation to the up-regulation of PUMA induced by NF-κB. The chemoresistance to Cyt was related to the up-regulation of Slug induced by Erk1/2, which inhibited the expression of PUMA.
Educational level influences contact with specialist care among patients with gynecological cancer alarm symptoms. Future studies should investigate inequalities in access to the secondary healthcare system.