Does calcium supplementation increase blood creatinine concentration in a randomized controlled trial?
Among healthy adults participating in a randomized clinical trial, daily supplementation with 1200 mg of elemental calcium caused a small increase in blood creatinine. If confirmed, this finding may have implications for clinical and public health recommendations for calcium supplementation.
These data largely confirmed the relevance of the gout OMERACT domains while identifying additional issues for patients that require further investigation.