Does broad-spectrum chemokine inhibition reduce vascular macrophage accumulation and collagenolysis consistent with plaque stabilization in mice?
Strategies, such as chemokine inhibition, to attenuate macrophage accumulation may therefore be useful to promote stabilization of atherosclerotic plaques.
Our observations suggest curettage and packing with bone graft/substitute can provide pain relief and allow full athletic recovery for young athletes with benign lytic bone lesions.