Does blockade of the interaction between PD-1 and PD-L1 accelerate graft arterial disease in cardiac allografts?
The PD-L1 pathway regulates both the proliferation of SMCs and GAD. Thus, control of this interaction is a promising strategy for suppression of GAD.
Cutoff values (3 SD above the means) of 52% for men and 48% for women are suggested by these data. However, the relationship of these cutoffs to either athlete safety or the ability to detect rules violations remains unknown.