Does ursodeoxycholic acid aggravate bile infarcts in bile duct-ligated and Mdr2 knockout mice via disruption of cholangioles?
UDCA aggravates bile infarcts and hepatocyte necroses in mice with biliary obstruction via disruption of cholangioles as a result of increased biliary pressure caused by its choleretic action.
In this study, a systematic activation of alarm soundings for non-invasive blood pressure monitoring seemed unnecessary for the safety of ICU patients.