Does sTI571 ( Gleevec ) improve tumor growth delay and survival in irradiated mouse models of glioblastoma?
These findings suggest that STI571 has the potential to augment radiotherapy and thereby improve median survival.
In patients with critical limb ischemia, EPC in peripheral blood were decreased compared with healthy individuals. However, in BM-MNC we found that relative numbers of CFU-EC could be used as an indicator to discriminate patients with neoangiogenic processes. These results need to be confirmed in a randomized study.