Is ischemia-modified albumin ( IMA ) useful for detecting myocardial ischemia during symptom-limited exercise stress tests?
Our results suggest that IMA has limitation in detecting myocardial ischemia during symptom-limited exercise stress tests.
Collectively, our data strongly support the new concept of TJs as a dynamic structure. Moreover, our results implicate TRAF4 in one of the emerging TJ-dependent signaling pathways that responds to cell polarity by regulating the cell proliferation/differentiation balance, and subsequently epithelium homeostasis. Drastic phenotypes or lethality in TRAF4-deficient mice and drosophila strongly argue in favor of such a function.