Is von Hippel-Lindau tumour suppressor gene involved in sporadic human breast cancer?
These results strongly indicate against a critical involvement of the tumour suppressor vhl in breast carcinogenesis.
Impairment of autophagy in pancreatic β-cells suppressed the expression of some mitochondrial respiratory complexes, and may contribute to mitochondrial dysfunction. Among the complexes, I and II seem to be most vulnerable to autophagy deficiency.