Is insulin sensitivity impaired in adults with varying degrees of GH deficiency?
Although not detected under basal conditions, hypopituitary adults with both severe GHD and GHI are insulin resistant under conditions of insulin stimulation. This finding may be explained by the concomitant adverse changes in body composition observed in both these states of varying degrees of GHD. Insulin resistance is associated with a number of adverse cardiovascular risk factors that may place patients with GHI at risk of premature cardiovascular disease.
These findings indicate that whole-plant respiration of rapidly growing plants has a small sensitivity to temperature, and that the sensitivity does not change among the species tested, even after 20 d of treatment. Finally, the results support respiration models that separate respiration into growth and maintenance components.