Is unrecognized anaphylaxis a cause of sudden unexpected death?
We conclude that mast cell activation may accompany up to 13% of sudden unexpected deaths in adults. Measurement of both tryptase and specific IgE antibody levels in post-mortem sera from persons experiencing sudden, unexpected death may identify a small subset of cases due to clinically unrecognized fatal anaphylaxis, including those due to insect stings.
These results suggest that the overexpression of caveolin-1 is significantly correlated with a poor prognosis in patients with PCL and that it is a marker for predicting prognosis in PCL.