Does abnormal mannose-6-phosphate receptor trafficking impair recombinant alpha-glucosidase uptake in Pompe disease fibroblasts?
These results indicate a role for disrupted CI-MPR trafficking in the variable response to ERT in PD and have implications for ERT efficacy and optimization of treatment protocols.
No differences were found between 1-stage and 2-stage implant placement in crestal bone loss after 1 year of functional loading.