Tuberous sclerosis: a primary pathology of astrocytes?
We conclude that astrocytes are the type of glial cell selectively impacted in cortical tuber pathology. We propose that tubers may be dynamic lesions, with progression of astrocytes over time from "reactive" to "gliotic." Tuber astrogliosis in TSC may represent a genetic "model" of gliosis that is phenotypically similar to gliosis seen in acquired human pathologies.
There was no significant decline in the postoperative verbal memory scores in those patients whose medial temporal structure of the language-dominant side had been removed.