Does dNA methylation signature in peripheral blood reveal distinct characteristics of human X chromosome numerical aberrations?
The presented data clearly show that gain or loss of an X chromosome results in different epigenetic effects, which are not necessary opposite.
In CI recipients with ANSD who demonstrate limited auditory skills development despite prolonged implant use, lowering the stimulation rate may facilitate acquisition of closed-set speech perception abilities. Further efforts on the study of programming parameters in ANSD patients with CIs are necessary to maximize auditory development in this patient population.