Is PSA related to serum cholesterol and does the relationship differ between black and white men?
Among prostate cancer-free men about to begin a statin, pre-statin total cholesterol and LDL were correlated with PSA levels in white, but not black men. If confirmed in future studies, these findings suggest that serum cholesterol may be related to prostate biology, and that this effect may vary by race.
The effective transmembrane delivery and increased efficacy validate its use as a potential therapeutic.