Is hIF-1 alpha expression associated with an atheromatous inflammatory plaque phenotype and upregulated in activated macrophages?
In atherosclerotic plaque, the transcription factor HIF-1 alpha is associated with an atheromatous inflammatory plaque phenotype and with VEGF expression. HIF-1 alpha expression is upregulated in activated macrophages under normoxic conditions.
Among these compounds, compounds II, III, VI are isolated from Dendrobium candidum for the first time.