Is aPOE epsilon4 associated with impaired verbal learning in patients with MS?
We found an association of APOE epsilon4 with impaired verbal learning in patients with multiple sclerosis.
Clinically relevant concentrations of halothane and isoflurane markedly depress K+-evoked increases in rat cerebrocortical synaptosomal calcium (Ca2+) unrelated to L-, N-, and P-type voltage-dependent calcium channels and increase the Ca2+ permeability of the synaptosomal membrane. These changes in Ca2+ dynamics could have profound effects on Ca2+ signaling in the synapse.