Do novel hydrophobically modified asymmetric RNAi compounds ( sd-rxRNA ) demonstrate robust efficacy in the eye?
These data support the potential of developing sd-rxRNAs as a therapeutic for ocular disease.
Detailed analysis of static pressure-volume data can identify pulmonary function abnormality and categorize the dominant mechanism responsible for restrictive ventilatory defects in survivors of ARDS, even in patients with normal lung volumes. In addition to lung fibrosis, neuromuscular weakness also contributes to decline in pulmonary function.