Does the high angiogenic activity in very early breast cancer enable reliable imaging with VEGFR2-targeted microbubbles ( BR55 )?
3D molecular ultrasound using BR55 is very well suited to depicting the angiogenic activity in very small breast lesions, suggesting its potential for detecting and characterising these lesions.
The results suggest that long-term administration of artesunate could induce reversible infertility in rats which may act via distortion of blood-testis barrier formed by Sertoli cells.