Surgery for renal cell carcinoma in two European urologic clinics: to compare or compete?
These numbers demonstrate more advantageous tumour features at the Italian clinic in terms of organ-sparing surgical options (open and laparoscopic), whereas in the Bulgarian clinic the tumour features pose certain limitations to the application of modern surgical techniques. This difference is due to early diagnosis of RCC in Italy, allowing treatment of smaller volume tumors.
These results suggest that endothelin plays an important role in the modulation of systemic blood pressure and renal function in SHR.