Complications of Cushing's disease - prospective evaluation and clinical characteristics. Do they affect the efficacy of surgical treatment?
Longer duration of CD is associated with a higher risk of glucose intolerance and/or diabetes. The overweight/obesity presented in the majority of patients increases the risk of secondary hypertension in CD. However, the efficacy of transsphenoidal surgery does not depend directly on either disease duration or type of occurring complications.
Burnout seems not to be associated with this proxy measure of allostatic load. The mediating physiological mechanisms between burnout and objective physical health remain to be elucidated.