Is expression of Brachyury gene a significant prognostic factor for primary lung carcinoma?
A positive association between Brachyury and Slug and IL-8, and a negative association with E-cadherin may lead to invasiveness and metastasis in primary lung carcinoma. Brachyury mRNA expression is a significant predictor of poor prognosis in primary lung carcinoma.
The results of our study agree with the data of the literature on the prevalence of prostate neoplasias with perilesional vascularisation. Since no significantly indicative diagnostic pattern has been found, at present we feel that echocolour and power Doppler do not significantly contribute to the diagnosis of prostate neoplasia or the guidance for bioptic samplings.