Does a novel anti-microtubule agent with carbazole and benzohydrazide structures suppress tumor cell growth in vivo?
Taken together, these findings suggest that HND-007 is a promising lead compound for development of novel anti-mitotic, anti-microtubule chemotherapeutic agents.
Suppression of phosphoinositide 3-kinase prevented many age-associated changes in the heart and preserved cardiac function of aged mice.