Does [ Interleukin-10 inhibit the activation of cultured rat hepatic stellate cells induced by Kupffer cells ]?
IL-10 reduces the level of TNF-alpha secreted by KC dose-dependently. Through reducing cytokine production by KC, IL-10 inhibits the activation of cultured rat HSC induced by KC, which may play a protective role against liver fibrosis.
Findings from the only large trial of AgPT suggest that AgPT may increase mortality while reducing impairment and profound impairment among the smallest and sickest infants. New approaches to reduce their serum bilirubin need development and rigorous testing.