Does cDX1 restrict the invasion of HTR-8/SVneo trophoblast cells by inhibiting MMP-9 expression?
Altogether, we found that in trophoblast cells, CDX1 reduced invasion independently of the PI3K/AKT signaling pathway. Furthermore, CDX1 functions in concert with PI3K/AKT signaling to regulate trophoblast invasion. We concluded that CDX1 restricts the invasion of HTR-8/SVneo trophoblast cells by inhibiting MMP-9 expression independently of the PI3K/AKT pathway.
Disaster medicine education for medical students is recommended by students and experts, while the applicability and feasibility needs further exploration.