Do patients with cartilage-hair hypoplasia have an increased risk for bronchiectasis?
Patients with cartilage-hair hypoplasia are at risk of the development of bronchiectasis.
Collectively, these findings validate the relationship between antibody response to brain induced by P. falciparum infection and plasma cytokine patterns with clinical outcome of malaria. They also provide significant insight into the immune mechanisms associated to CM by the identification of TBB3 as a new disease-specific marker and potential therapeutic target.