Do impact of active patient follow-up on worst-case implant survival analysis?
The findings demonstrate improvement in long-term implant survival with the sequential capture of young and active patients undergoing BHR who were initially considered lost to follow-up. The results reiterate the recommendation that every effort should be made to follow all patients up after joint replacement. This will improve the accuracy of survival reporting and assist comparison between different prostheses.
To better understand the underlying genetics of isoflavone accumulation, we performed a large scale analysis to identify genomic regions associated with isoflavone concentrations. We not only identified a number of such regions, but also found that they can interact with one another and with the environment to form a complex adaptable network controlling seed isoflavone levels. We also found putative candidate genes in several regions and overall we advanced the knowledge of the genetics underlying isoflavone synthesis.