Is increased neutrophil-to-lymphocyte ratio associated with disease-specific mortality in patients with penile cancer?
The pretreatment NLR may function as a biomarker that precisely predicts the prognosis in patients with penile cancer.
These findings suggest that TLR-4 is functional in HEECs and its activation by bacterial LPS induces a specific cytokine/chemokine response. However, bacterial LPS also induced tissue factor expression in what seemed to be a TLR-4-independent fashion, suggesting that this bacterial component can act on the HEECs through TLR-4-dependent and TLR-4-independent pathways. These findings indicate that endometrial endothelial cells may play an active role in uterine innate immunity.