Is a change in promoter methylation of hMLH1 a cause of acquired resistance to platinum-based chemotherapy in epithelial ovarian cancer?
A change in hMLH1 MET is a major molecular cause of acquired resistance to Pt-chemo in EOC.
Prolonged physiologic instability was associated with deleterious neurodevelopmental consequences for extremely premature infants through 2 to 3 years of age, independent of effects of intracranial abnormalities and GA.