Are neuroprotective effects of enriched environment housing after transient global cerebral ischaemia associated with the upregulation of insulin-like growth factor-1 signalling?
Ultimately, these findings suggest the possibility that IGF-1 signalling may be one of the underlying mechanisms involved in the beneficial effects of EE in optimizing recovery following cerebral ischaemic injury.
No significant differences were detected in prevalence of QTc prolongation or mean QTc among patients before and after 18 weeks on clozapine.