Do human oviductal cells reduce the incidence of apoptosis in cocultured mouse embryos?
Human oviductal cells improved mouse embryo development partly by decreasing the incidence of apoptosis.
These observations show, for the first time, the structural and functional overexpression of Cdx2 by human colorectal tumors compared with matched normal mucosa. They suggest that loss of Cdx2 expression or transcriptional activity is an infrequent event during tumorigenesis, which does not contribute to molecular mechanisms underlying initiation and progression of most colorectal tumors.