Is Barrett's metaplasia the source of adenocarcinomas of the cardia?
Adenocarcinomas located at the gastroesophageal junction were associated with Barrett's metaplasia in nearly one half of the patients. The length of the Barrett segment tends to be short and may be missed during endoscopy. The presence of high-grade dysplasia within Barrett's mucosa supports a barrett's origin for half of the adenocarcinomas arising at this location.
Our results show higher expression of E6/E7 in samples with episomal unmethylated virus having sequence variations in LCR.