Does cigarette Smoke modulate NOD1 Signal Pathway and Human β Defensins Expression in Human Oral Mucosa?
The present study indicated that cigarette smoke could potentially modulate the expression of crucial molecules of NOD1 signal pathway and hBDs in human oral mucosal epithelium. NOD1 signal pathway could play an important role in the regulatory effects of CSE on hBDs levels in oral mucosal epithelial cells.
The variant of COL1A2 could be a genetic risk factor for IA patients with family history.