Is defibrillation success with high frequency electric fields related to degree and location of conduction block?
HFAC fields induce a field-dependent state of CB, and defibrillation success is related to the degree and location of the CB.
This study demonstrates that GP Ibalpha is a physiologically relevant ligand for alphaMbeta2 and that integrin engagement of GP Ibalpha is critical to leukocyte function and the biological response to vascular injury. These observations establish a molecular target for selectively disrupting leukocyte-platelet complexes that promote inflammation in thrombosis and restenosis.