Is septic arthritis in adults with sickle cell disease often associated with osteomyelitis or osteonecrosis?
The incidence of septic arthritis in adults with SCD is low, but often is associated with osteomyelitis or osteonecrosis.
Desmosomal mutations linked to ARVC do not significantly affect cell mechanical properties, but cause myocytes to respond abnormally to mechanical stress through a mechanism involving GSK3β. These results may help explain why patients with ARVC experience disease exacerbations following strenuous exercise.