Are elevated levels of autophagy-related marker ULK1 and mitochondrion-associated autophagy inhibitor LRPPRC associated with biochemical progression and overall survival after androgen deprivation therapy in patients with metastatic prostate cancer?
High expression of ULK1 concomitant with high expression of LRPPRC may serve as useful markers for shorter BCP-free survival and OS in patients with metastatic PCa after ADT.
Tumor stage in cancers diagnosed in breast screening units progressively decreased when the program was being implemented. There is a maximum level among which tumor characteristics remain constant. Changes in screening programs can modify these characteristics.