Are perioperative plasma active and total ghrelin levels reduced in acromegaly when compared with in nonfunctioning pituitary tumours even after normalization of serum GH?
The putative negative feedback mechanism of GH on ghrelin secretion may in part account for the low ghrelin levels observed in acromegalic patients, and the mechanism may persist even after normalization of serum GH.
These results suggest that adult coronary artery contains Ang1-Tie2 components that enhance endothelial cell survival to help maintain the normal integrity of the coronary artery endothelium.