Does prior contralateral amputation predict worse outcomes for lower extremity bypasses performed in the intact limb?
Patients with prior contralateral amputations who present with CLI in the intact limb represent a high-risk population, even among patients with advanced peripheral arterial disease. When considering LEB in this setting, both physicians and patients should expect increased rates of perioperative adverse events, increased rates of 1-year graft occlusion, and decreased rates of limb salvage, when compared with patients who have not undergone a contralateral amputation.
MCP-1 might play a role in the development of delirium.