Is myocardial calcium-independent nitric oxide synthase activity present in dilated cardiomyopathy , myocarditis , and postpartum cardiomyopathy but not in ischaemic or valvar heart disease?
These results support the hypothesis the generation of nitric oxide by iNOS accounts for some of the dilatation and impaired contractility associated with inflammatory and non-inflammatory dilated cardiomyopathy and peripartum cardiomyopathy.
The effect of SDF-1 in promoting MSC migration is related to mitogen-activated protein kinase, phosphatidylinositol phospholipase C, and protein kinase signal pathways.