Does autophagy gene ATG16L1 influence susceptibility and disease location but not childhood-onset in Crohn 's disease in Northern Europe?
The ATG16L1 variant is associated with susceptibility to adult CD in Scotland, but not early-onset disease. These contrasting effects are primarily driven by differences in disease location between early-onset and adult-onset disease.
Our results suggest that crude venom from Pelagia noctiluca alters cell membrane transport in human erythrocytes.