Is the metabolic syndrome a discrete diagnostic category or the end of a continuum?
The results indicate that the metabolic syndrome is continuously distributed in nature, rather than a discrete diagnostic category.
Better prediction tools to estimate more precisely the risk for death due to comorbid illness versus breast cancer are needed. In some patients, the risks of therapy could outweigh the benefits. Treatment selection for T1a,bN0 HER2-positive cancers remains in the transition area between evidence- and subjective judgment-based medicine.