Hypertension is associated with preamyloid oligomers in human atrium: a missing link in atrial pathophysiology?
PAOs are frequently detected in human atrium, where their presence is associated with clinical hypertension.
Inter-residue distances have proved useful in showing the explicit relationship between contact preferences and evolutionary substitution rates. It is proposed that the distance matrix derived from structural analysis may be useful in aligning proteins where remote homologs share structural features. Residue vectors derived from the distance matrix illustrate the spatial arrangement of residues and point to ways in which they can be grouped.