Is reduced immunoglobulin M associated with sinus mucosal thickening , osteitis and sinus surgery in patients with common variable immunodeficiency?
This is the first study to show that sinus mucosal thickening on CT in patients with CVID is inversely related to serum IgM levels.
During the follow-up, the patients with delayed diagnosis VUP have developed fewer complications related to the initial obstruction than the population who was detected antenatally and managed from the early hours of life. However, the rate of IRF and voiding disorders in our study, associated with the data of the literature, highlights the potential persistence and worsening of these conditions. That is why, whatever the age at diagnosis, VUP patients require a close monitoring.