Is acute insulin response of donors correlated with pancreatic islet isolation outcome in the pig?
This study suggests that the donor's pancreatic endocrine mass, as estimated by AIR, is a major determinant of the outcome of islet isolation in large mammals. Our results may explain the frustrating variability of human islet isolation outcome and could lead to a new approach for optimising the selection of brain-dead and/or living pancreas donors.
TSAb is strongly associated with TAO in HT and TSAb may contribute to the pathophysiology of TAO.