Does cardiopulmonary bypass increase coronary IL-8 in diabetic patients without evidence of reperfusion injury?
This study demonstrates an early decrease in IL-8 in both groups, most likely related to depressed production secondary to hypothermia. The subsequent elevation in IL-8 only in the diabetic group was seen without concomitant conjugated diene elevation. While no evidence of reperfusion injury was demonstrated in this time frame, the elevation of IL-8 in diabetics after CABG may contribute to later infiltration and associated oxidative damage.
Recently trained family physicians do not assess most lifestyle risk factors any better than their more experienced colleagues.