Does subcutaneous and continuous administration of lipopolysaccharide increase serum levels of triglyceride and monocyte chemoattractant protein-1 in rats?
These findings suggest that chronic infection such as periodontal disease induces hypertriglyceridemia and increases serum MCP-1 levels in a manner that increases the risk of atherosclerotic cardiovascular disease.
Statins may exert protective effect against GI bleeding in patients with ACS. Additional studies are warranted to explore this additional potential benefit of statins.