Is a common deletion in the uridine diphosphate glucuronyltransferase ( UGT ) 2B17 gene a strong determinant of androgen excretion in healthy pubertal boys?
In pubertal boys, a common homozygous deletion in the UGT2B17 gene strongly affected urinary excretion pattern of androgen metabolites but did not influence circulating androgen levels.
These results have important implications for the development of vaccines and therapeutical strategies against HIV infection.