Is b lymphopenia in uremia related to an accelerated in vitro apoptosis and dysregulation of Bcl-2?
Our data indicate that B lymphopenia in CRF may be partially attributed to an increased susceptibility to cell death by apoptosis that is associated with a decreased expression of Bcl-2.
These results suggest MHC genes are associated with basal pain sensitivity, which may contribute to the identification of pain sensitivity and/or individually tailored pain treatment regimens.