Does [ CpG oligodeoxynucleotide enhance humoral and cellular immune responses against HBsAg in mice ]?
(1) CpG ODN markedly improves humoral (anti-HBs) and cellular immune response (CTL) induced by HBsAg immunization. (2) There is a synergistic interaction between aluminum and CpG ODN in enhancing the humoral and cellular immune responses against HBsAg. Therefore, CpG ODN might be used to treat chronic hepatitis B virus infection after its safety and effectiveness have been confirmed.
In this prospective population-based study, diabetes mellitus was not a risk factor for OAG.