Does high dose cyclophosphamide preferentially target naïve T ( CD45/CD4/RA+ ) cells in CIDP and MS patients?
Cyclophosphamide effectiveness in autoimmune illness may result from Naïve T-cell destruction, as this compartment may be the source of autoreactive lymphocytes.
The release of high amounts of FABP1 and FABP3 in urine of AKI patients could serve as a diagnostic/prognosis marker for RRT initiation in these patients.