Are genetic polymorphisms in ZFHX3 associated with atrial fibrillation in a Chinese Han population?
In summary, our study investigated the role of genetic variants of ZFHX3 in AF and two SNPs (rs2106261, rs6499600) showed significant associations while rs16971436 conferred a borderline significant association with AF risk in Chinese Han populations. However, further large and functional studies are warranted to confirm our findings.
Lower CBF, in particular in the posterior brain regions, may have value as a prognostic marker for rate of cognitive decline in AD.