Do patients With Coronary Endothelial Dysfunction Have Impaired Cholesterol Efflux Capacity and Reduced HDL Particle Concentration?
Cholesterol efflux capacity and HDL-PIMA are reduced in subjects with coronary ED, independently of HDL-C. Alterations in HDL-PIMA and HDL itself account for a much larger fraction of the variation in cholesterol efflux capacity than does HDL-C. A selective decrease in large HDL particles may contribute to impaired cholesterol efflux capacity in ED subjects. These observations support a role for HDL size, concentration, and function as markers-and perhaps mediators-of coronary atherosclerosis in humans.
This retrospective study proves the clinical efficiency of using skin xenografts for the treatment of partial-thickness scald burns. Skin xenografts showed good adherence on the wound surfaces, decreased the amount of exudate and reduced pain. In addition, the risk of hypertrophic scar formation was lower when wound healing was achieved within 14 days.