Does prostaglandin E2 receptor subtype 2 ( EP2 ) regulate microglial activation and associated neurotoxicity induced by aggregated alpha-synuclein?
Thus, it appears that microglial EP2 plays a critical role in alpha-synuclein-mediated neurotoxicity.
Beta cell nuclear MafA is markedly decreased in humans with type 2 diabetes, which may contribute to impaired beta cell dysfunction.