Does congenital diaphragmatic hernia associated with bronchopulmonary sequestration portend a better prognosis?
Given the limited series, we cannot conclude that bronchopulmonary sequestration confers an anatomic advantage to patients that have CDH. We did observe survivors in this group that, given their antenatal predictors of CDH severity, would ordinarily have dismal prognosis. The presence of a sequestration may be protective in a subset of patients with severe CDH, or may confound our antenatal predictors of disease severity in these patients.
This suggests that genetic variation in the STAT-6 gene may be associated with predisposition to allergic diseases.