Does phosphatidylinositol 3-kinase/Akt pathway regulate inflammatory mediators-induced calcification of human vascular smooth muscle cells?
These data suggest that PI3K/Akt pathway may play an inhibitory role in IM-induced HVSMC calcification through regulating ALP expression.
We believe that we have established a representative murine model of postangioplasty restenosis, which may serve to elucidate the mechanisms underlying restenosis and to evaluate potential antirestenotic therapies.