Do apoptotic eosinophils express IL-2R chains alpha and beta and co-stimulatory molecules CD28 and CD86?
Our data suggest that apoptotic eosinophils have a unique signalling system and might function in ways different from the role of the living eosinophil. The apoptotic eosinophil expresses markers that indicate communication with lymphocytes and antigen-presenting cells.
Elevated miRNA-122 levels are associated with liver injury, and with low HVPG. Though, miRNA-122 levels are not suitable to predict the degree of fibrosis, they might function as indicators for portal hypertension in HIV/HCV coinfected patients.