Does dextromethorphan attenuate LPS-induced adhesion molecule expression in human endothelial cells?
Dextromethorphan inhibits the adhesive capacity of HUVECs by reducing the LPS-induced ICAM-1 and VCAM-1 expression via the suppression of the ERK, Akt, and NF-κB signaling pathways. Thus, DXM is a potential anti-inflammatory therapeutic that may modulate atherogenesis.
Axillary liposuction did not alter the pathological features of lymph nodes in our study.