Does vascular endothelial growth factor-C promote alloimmunity by amplifying antigen-presenting cell maturation and lymphangiogenesis?
These data suggest VEGF-C as a potentially important target in corneal transplant pharmacotherapy and immunobiology.
Further, series of investigations are, however, necessary to remain exploration, which includes their structural elucidation, characterization, clinical safety, reliability and molecular mechanism involved in this pharmacological activity.