Is minocycline therapy in acne associated with antineutrophil cytoplasmic antibody positivity?
ANA positivity is seen in patients with acne irrespective of exposure to MN; however, p-ANCA appear to be a serological marker for developing autoimmune disease in patients receiving MN.
Sgk1 expression was increased in HFD mice though there was no difference in aldosterone secretion between NFD mice and HFD mice. Our salt-adjusted models in this study revealed that MR sensitivity is enhanced in HFD mice. Therefore they can be good models to study detailed mechanisms of enhanced MR sensitivity in obesity-related hypertension, which is a clinically observed hypertension well-controlled by MR antagonists.