Does cystic fibrosis gene mutation reduce epithelial cell acidification and injury in acid-perfused mouse duodenum?
Increased cellular buffering power of the epithelial cells of DeltaF/DeltaF mice likely protects against acidification and injury during acid exposure. We speculate that this protective mechanism partially underlies the perceived relative lack of peptic ulceration in patients affected by cystic fibrosis.
These data indicate that the effects of iTBS can be enhanced and prolonged by nicotine.