Does human herpesvirus-8 infection lead to expansion of the preimmune/natural effector B cell compartment?
Our results indicate that long-lasting HHV-8 infection promotes an imbalance in peripheral B cell subsets, perturbing the equilibrium between earlier and later steps of maturation and activation processes. This observation may broaden our understanding of the complex interplay between viral and immune factors leading HHV-8-infected individuals to develop HHV-8-associated malignancies.
Diet rich in SFA from animal sources may influence TXA2 formation via effect on tissue proportion of 20:4n-6.