Is highly specific antiangiogenic therapy effective in suppressing growth of experimental Wilms tumors?
Anti-VEGF165 aptamer effectively suppressed primary tumor growth in experimental animals with no observed adverse effects. Development of highly specific antiangiogenic therapies may be of particular benefit to pediatric patients.
Results seem to suggest that experts in mental health promotion might want to take into account socioeconomic differences in attitudes and coping skills which may influence psychosocial adjustment and health among youth. While parents from lower social classes may lack the necessary material and psychosocial resources, therapy sessions and special programs could contribute to strengthening certain attitudes (such as optimism) and thus lowering social inequalities in health later in adulthood.