Does vitamin C improve endothelial function of conduit arteries in patients with chronic heart failure?
Vitamin C improves FDD in patients with CHF as the result of increased availability of nitric oxide. This observation supports the concept that endothelial dysfunction in patients with CHF is, at least in part, due to accelerated degradation of nitric oxide by radicals.
Urban pediatric pedestrian crashes are common and occur most frequently during optimal driving conditions (good lighting, a dry road, and good weather). The data also suggest that pedestrian crashes are related to the saturation of the streets with children (optimal play conditions) compounded by poor street-crossing technique. Prevention efforts should reinforce the fact that optimal driving conditions are also likely to represent optimal conditions for child play and may increase the risk for pediatric pedestrian injuries through increased exposure.