Does monoacylglycerol lipase inhibitor protect primary cultured neurons against homocysteine-induced impairments in rat caudate nucleus through COX-2 signaling?
These data suggest that the MAGL inhibitor is a promising therapeutic target for some neurodegenerative disorders, such as AD, via the COX-2 signaling pathway.
The current study provides the first evidence that RL-14 cells express CYP isoenzymes at comparable levels to those expressed in the primary cells and thus offers a unique in vitro model to study DMEs in the heart.