Is polymorphism of the pre-miR-146a associated with risk of cervical cancer in a Chinese population?
Our study suggests that the risk of cervical cancer in a Chinese population partly results from miRNA-146a expression deviation in vivo, being caused by common polymorphism in miR-146a. This is an initial study to indicate that miR-146a (rs2910164) might contribute to cervical cancer susceptibility.
Maldi 531.2[M + H]+ may be a potential anti-cancer drug candidate whose mode of action include reduction of the mitochondrial membrane potential and induction of apoptosis.