Is remodeling of retinal Fatty acids in an animal model of diabetes : a decrease in long-chain polyunsaturated fatty acids associated with a decrease in fatty acid elongases Elovl2 and Elovl4?
This is the first comprehensive study demonstrating diabetes-induced changes in retinal fatty acid metabolism. Normalization of retinal fatty acid levels by dietary means or/and modulating expression of elongases could represent a potential therapeutic target for diabetes-induced retinal inflammation.
Splenectomy may have a beneficial effect on lung function although this may not manifest itself until the second year post-splenectomy. Splenectomy in patients with CFLD appears to be a safe procedure.