Is thicker posterior insula associated with disease duration in women with irritable bowel syndrome ( IBS ) whereas thicker orbitofrontal cortex predicts reduced pain inhibition in both IBS patients and controls?
This study investigated the brain morphology of IBS patients. IBS patients showed thicker right pINS, associated with longer disease duration but not with psychological symptoms. This suggests that IBS induces thickening of pINS, which may contribute to its pathophysiology, consistent with the role of the pINS in interoception and pain.
The questionnaire was shown not to be useful for diagnosing GER as a complication in diabetic patients. We, therefore, should not diagnose GER as a complication in diabetes mellitus on the basis of the questionnaire.