Does tissue transglutaminase regulate focal adhesion kinase/AKT activation by modulating PTEN expression in pancreatic cancer cells?
TG2 expression in PDAC promotes degradation of PTEN by ubiquitin-proteasomal pathway and results in constitutive activation of focal adhesion kinase/AKT cell survival signaling.
HFAC fields induce a field-dependent state of CB, and defibrillation success is related to the degree and location of the CB.