Does a celecoxib derivative potently inhibit proliferation of colon adenocarcinoma cells by induction of apoptosis?
A slight modification of celecoxib enhanced the pro-apoptotic effect on colon adenocarcinoma cells.
These formulations can be of value in gene transfer to cells and tissues in which adenoviral infection is limited due to a lack of fiber and alpha(v) integrin receptors. They are simple to prepare and do not affect the ability of the virus to transduce target cells.