Is nuMA required for proper spindle assembly and chromosome alignment in prometaphase?
Our data confirm that NuMA is important for spindle pole formation, and for cohesion of centrosome-derived microtubules with the bulk of spindle microtubules. Our findings of NuMA-dependent defects in chromosome alignment suggest that NuMA is involved in stabilizing kinetochore fibres.
EMLA does not permit pain-free retrobulbar injection.