Evidence-based medicine: is the evidence out there for primary care clinicians?
Guidelines are useful resources for primary care clinicians, answering two-fifths of questions.
This proof-of-principle study demonstrates that salsalate reduces glycemia and may improve inflammatory cardiovascular risk indexes in overweight individuals. These data support the hypothesis that subacute-chronic inflammation contributes to the pathogenesis of obesity-related dysglycemia and that targeting inflammation may provide a therapeutic route for diabetes prevention.