Is sex distribution a factor in teratogenically induced clefts and in the anti-teratogenic effect of thiamine in mice , but not in genetically determined cleft appearance?
There was a strong anti-teratogenic effect of vitamin B1, especially in the male fetuses. Genetically determined cleft appearance was not positively influenced. These findings confirm observations about cleft appearance in human beings.
Corneal dryness stimulates production of certain MMPs in a strain-dependent fashion and causes the disruption of the corneal barrier, thus increasing permeability and corneal irregularity.