Can admission and fasting glucose reliably identify undiagnosed diabetes in patients with acute coronary syndrome?
A high prevalence of abnormal glucose tolerance was seen in patients with acute coronary syndrome. The combination of FPG>or=5.6 mmol/l (100 mg/dl) and/or APG>or=7.8 mmol/l (140 mg/dl) was highly sensitive for identifying diabetes. Although weakly specific, this simple algorithm could offer a practical initial screening tool at the acute setting in the high-risk population with acute coronary syndrome.
Epigenetic changes in a group of glycosyltransferases including B4GALNT2 and ST3GAL6 represent a malignant phenotype of gastric cancer caused by silencing of the activity of these enzymes, which action may eventually induce aberrant glycosylation and expression of cancer-associated carbohydrate antigens.