Are gray matter volumes of pain-related brain areas decreased in fibromyalgia syndrome?
Increasing evidence supports the association of chronic pain with accelerated gray matter atrophy in pain disorders like low back pain, IBS, and FM syndrome. However, cause-effect relationships between chronic pain and decreased gray matter volumes have not been established yet and will require future prospective studies.
Our findings implicate GAB2 as a susceptibility gene for LOAD in Han Chinese.