Fear of failure: are we doing too many trials of instrumental delivery in theatre?
Unsuccessful trials are associated with maternal rather than neonatal morbidity. The shortening of duration training as well as reduction of working hours in the United Kingdom has led to obstetric trainees being less experienced in conducting instrumental deliveries. Thus, many junior trainees may prefer to conduct relatively uncomplicated instrumental deliveries in theatre. Appropriate training and senior staff input would help reduce this.
Many genes with altered expression associated with a metastatic prostate cancer phenotype were identified. Further validation of these genes in human prostate samples will determine their usefulness as biomarkers for early diagnosis of recurrence or metastasis of prostate cancer, as well as potential therapeutic targets for this disease.