Do programmatically selected multidrug-resistant strains drive the emergence of extensively drug-resistant tuberculosis in South Africa?
XDR-TB associated genotypes in South Africa probably were programmatically selected as a result of the standard treatment regimen being ineffective in preventing their transmission. Our findings call for an immediate adaptation of standard treatment regimens for M/XDR-TB in South Africa.
Midazolam appears to cause significantly less sedation and cognitive impairment in red haired subjects.