Does cluster Differentiating 36 ( CD36 ) Deficiency attenuate Obesity-Associated Oxidative Stress in the Heart?
CD36 deficiency prevented obesity-associated cardiac steatosis and insulin resistance, and reduced NADPH oxidase-dependent ROS production. The study demonstrates that CD36 regulates NADPH oxidase activity and mediates FA-induced oxidative stress.
These data suggest that teicoplanin levels of>or = 20 mg/l for bone and joint infection in stable adult patients are best achieved with a daily dose of at least 600 mg.