Does bone morphogenetic protein 2 promote transforming growth factor β3-induced chondrogenesis of human osteoarthritic synovium-derived stem cells?
SDSCs could be isolated from human osteoarthritic synovium. Supplementation with BMP-2 significantly promoted the in vitro TGF-β3-induced chondrogenic differentiation of SDSCs.
Our study suggests that TCL1 expression profile may have a role in the prediction of overall outcome in patient with MCL and call for prospective studies.