Is azathioprine or mercaptopurine-induced acute pancreatitis a disease-specific phenomenon?
In this study, the alleged higher cumulative incidence of thiopurine-induced acute pancreatitis in Crohn's disease compared with vasculitis or UC patients was not confirmed. Female gender appears to be a risk factor for developing thiopurine-induced acute pancreatitis in IBD patients.
The study does not employ a traditional stress paradigm; instead it introduces a novel design to assess HPA axis functioning in relation to everyday emotional challenges.