Does hyperintense cortical signal on magnetic resonance imaging reflect focal leukocortical encephalitis and seizure risk in progressive multifocal leukoencephalopathy?
Seizures are a frequent complication in PML. HCS is associated with seizures and IRIS, and correlates histologically with JCV focal leukocortical encephalitis.
Our study shows that PC significantly decreases the re-excision in patients undergoing BCS with primary T2 breast tumors. This data suggests that any patient with a tumor greater than 2 cm might be considered for PC to increase BCS success with final negative margins.