Is early virological response as predictive of the hepatitis C treatment response in dialysis patients as in non-uremic patients?
The presence of HCV RNA at week 12 had a high negative predictive value for SVR in hemodialysis patients with chronic hepatitis C treated with IFN for 48 weeks. Therefore, if HCV RNA is detected at week 12, treatment should be discontinued due to the low probability of a sustained response.
COX deficiency and mtDNA abnormalities do not contribute to optic nerve dysfunction in pure DOA.