Is suppression of the phytohemagglutinin response to lymphocytes an independent prognosticator in patients with squamous cell carcinoma of the esophagus?
A suppressed PHA response is an additional significant prognosticator for SCC of the esophagus.
Based on these results, BCRP could play an important role in the resistance to leflunomide and A771726 via interactions with these drugs. BCRP may also mediate drug-drug interactions when leflunomide is administered with other BCRP substrate drugs such as methotrexate.