Is human atopic dermatitis complicated by eczema herpeticum associated with abnormalities in IFN-γ response?
Patients with ADEH(+) have reduced IFN-γ production, and IFNG and IFNGR1 SNPs are significantly associated with ADEH(+) and may contribute to an impaired immune response to herpes simplex virus.
Inhibition of LAT1 may be a new rationale to the effective therapy of NSCLC without EGFR mutation.