Does continuous positive airway pressure modulate effect of inhaled nitric oxide on the ventilation-perfusion distributions in canine lung injury?
Although pulmonary vascular resistance can be lowered with NO inhalation alone, recruitment of gas exchange units with CPAP is necessary to produce a beneficial effect of NO inhalation on VA/Q matching and oxygenation. When recruitment of gas exchange units with CPAP brings gaseous NO in contact with enough pulmonary blood vessels, NO-induced vasodilation will augment VA/Q matching by a steal mechanism.
The considerable anti-invasive potential of RECK points to new therapeutic possibilities for prostate cancer.