Does mitochondrial dysfunction enhance the migration of vascular smooth muscles cells via suppression of Akt phosphorylation?
Defective insulin signaling and mitochondrial function may collectively contribute to developing cardiovascular disease.
TS induced cardiac remodeling, associated with increased inflammation, oxidative stress, apoptosis, and changed energy metabolism. PX attenuated cardiac remodeling by reducing oxidative stress and improving cardiac bioenergetics, but did not act upon cardiac cytokines and apoptosis.