Is thrombospondin-1 a plasmatic marker of peripheral arterial disease that modulates endothelial progenitor cell angiogenic properties?
TSP-1 is a potential biomarker of PAD and ECFC-induced angiogenesis, suggesting that TSP-1 modulation might improve local tissue ischemia in this setting. (
Impaired insulin release might contribute to the glucose intolerance associated with hypertension, and this can occur in the absence of insulin resistance, which is not present in all subjects with essential hypertension.