Is the extent of inflammation a predictor for pouch-related complications in ileal pouches in patients with ulcerative or indeterminate colitis?
The extension of inflammation into the muscularis propria appears to predict pouch-related complications following restorative proctocolectomy for UC or IC.
Our data indicate that both keratin 8 mutations, G62C and Y54H, do not play a relevant pathogenic role in inflammatory bowel disease.