Is neddylation and deneddylation of CUL-3 required to target MEI-1/Katanin for degradation at the meiosis-to-mitosis transition in C. elegans?
We conclude that both neddylation and deneddylation of CUL-3 is required for MEI-1 degradation and propose that cycles of CUL-3 neddylation and deneddylation are necessary for its ligase activity in vivo.
Stable preterm infants tolerated brief changes in head position from midline without significant alternation in bilateral SctO2; the impact on critically ill infants needs further evaluation.