Clonidine and glucagon stimulation for testing growth hormone secretion in children and adolescents: can we make it with fewer samples?
For clonidine tests we can omit blood sampling at time points 0 and 30 min without significantly compromising accuracy.
Fasting for one day protects from hepatic IR injury via Sirt1-dependent downregulation of circulating HMGB1. The reduction in serum HMGB1 appears to be mediated by its engagement in the autophagic response. These findings integrate Sirt1, HMGB1, and autophagy into a common framework that underlies the anti-inflammatory properties of short-term fasting.