Does interferon γ-Induced Nuclear Interleukin-33 potentiate the Release of Esophageal Epithelial Derived Cytokines?
Esophageal epithelial cells can actively participate in GERD pathogenesis through the production of various cytokines, and epithelial-derived IL-33 might play a central role in the production of these cytokines.
Our study indicated that Tregs participate in intestinal inflammatory responses induced by IRI and that targeting Tregs could be a novel therapeutic approach to intestinal IRI.