Is new visual prostate symptom score useful as International Prostate Symptom Score in the evaluation of men with lower urinary tract symptoms?
The VPSS correlates significantly with the IPSS and can be reliably used in the elderly and low-educated patients for the assessment of symptom severity in men with lower urinary tract symptoms.
The results show that functional point mutations in the p16(INK4a) promoter region likely contribute to the initiation/progression of cholangiocarcinoma in PSC. Promoter mutations in CpG islands may function as a methylation equivalent phenomenon resulting in gene inactivation.