Is proteolysis in severe sepsis related to oxidation of plasma protein?
Severe sepsis results in oxidation of plasma proteins and this precedes and is related to the loss of body protein.
In a rabbit atherosclerotic model, SCM-198 dose-dependently ameliorated the progression of atherosclerotic lesions and vascular dysfunction accompanied by the suppression of inflammatory factors and oxidative stress. These findings suggested that SCM-198 might be a potential agent for the treatment of atherosclerosis.