Does activation of cyclic AMP pathway prevent CD34 ( + ) cell apoptosis?
Altogether, our results strongly suggest that cAMP appears to be not only a key pathway controlling CD34(+) survival, but also a mediator of the TPO-, G-CSF- and SCF-mediated cytoprotection.
Bendamustine induces durable responses with acceptable long-term safety in rituximab-refractory indolent NHL.