Do transcriptional and post-transcriptional regulation of retrotransposons IAP and MuERV-L affect pluripotency of mice ES cells?
Inadvertent REs instability may have important consequences for the use of ES cells in transgenesis (chimera formation) or in cell therapy.
The generation of an automated mathematical model to represent complex aortic geometry is feasible and reproducible in the context of high-resolution CT data. This process has been validated in 15 patients, where results corresponded with manual measurements that were used to successfully implant customized devices that accommodate the imaged vessels. Additional attributes include the expression of the 3D aorta in a compact form (on the order of kilobytes) for purposes of data storage, transfer, and other manipulations.