Is upregulation of AT1R and iNOS in the rostral ventrolateral medulla ( RVLM ) essential for the sympathetic hyperactivity and hypertension in the 2K-1C Wistar rat model?
The present study suggests that upregulation of AT(1)R and iNOS in the RVLM is important in the maintenance of high blood pressure and renal sympathetic activation in 2K-1C hypertension.
The present study indicated that the administration of G-CSF prevents elastin breakdown of the coronary arteries by enhancing the number and functions of EPCs via the NO system, and then accelerates the repair of coronary artery lesions in the KD.