Do deletion and duplication of 16p11.2 are associated with opposing effects on visual evoked potential amplitude?
The results of this study suggest that recording VEP is a useful method to assay cortical processing in children with 16p11.2 copy number variation. There is a gene dosage-dependent effect on P1 amplitude that merits further investigation. The VEP is directly translatable to animal models, offering a promising way to probe the neurobiological mechanisms underlying cortical dysfunction in this developmental disorder.
Association between FGFR2 and BPD is worthy of further confirmation.