Is transfusion-related acute lung injury in cardiac surgery patients characterized by pulmonary inflammation and coagulopathy : a prospective nested case-control study?
Prior to onset of transfusion-related acute lung injury, there is systemic inflammation and neutrophil sequestration. Transfusion-related acute lung injury is characterized by both systemic and pulmonary inflammation and activation of neutrophils, as well as enhanced coagulation and suppressed fibrinolysis.
Opening of KATP channels is essential for simvastatin-induced renal protection against I/R injury.