Dropping the shelf examination: does it affect student performance on the United States Medical Licensure Examination Step 2?
Dropping the shelf examination coincided with a decrease in performance on the USMLE Step 2 pediatric subtest in comparison with the US/Canadian mean. Similar decreases in performance in overall and USMLE Step 2 internal medicine subtest scores also occurred. Numerous confounding variables make it difficult to determine the effect of the shelf exam on Step 2 performance.
In C3-/- mice alcohol-induced liver steatosis is absent or strongly reduced after chronic or acute alcohol exposure. This suggests that the complement system and its component C3 contribute to the development of alcohol-induced fatty liver and its consequences.