Is cancer stem cell marker in circulating tumor cells : expression of CD44 variant exon 9 strongly correlated to treatment refractoriness , recurrence and prognosis of human colorectal cancer?
CD44v9 mRNA in the CTCs of colorectal cancer is useful as a factor predicting recurrence, prognosis, and treatment efficacy.
PCNA/Ki67 ratio excess may not reflect DNA excision repair activity but rather slow degradation of antigen bearing structures limiting relevance to drug resistance study.