Do multiple biological pathways link cognitive lifestyle to protection from dementia?
An active cognitive lifestyle was associated with protection from cerebrovascular disease in men, but there was no evidence for Alzheimer disease modification or hippocampal neuroprotection. Men and women both exhibited neurotrophic changes in the prefrontal lobe linked to cognitive lifestyle, consistent with a compensatory process. Lifespan complex cognitive activity may therefore protect against dementia through multiple biological pathways.
Alcohol use is not independently associated with increased prevalence of cavitary disease in adult patients with TB.