Surgical treatment of Crohn's disease of the large intestine: do rectal complications influence the results of ileorectal anastomosis?
Moderate proctitis does not increase the morbidity of total colectomy with IRA for Crohn's disease. The risk of reoperation and secondary protectomy is higher when proctitis was present, but the IRA was still functional in one-half of patients after more than 10 years of follow-up.
Transgene modulation of antioxidant enzyme defenses against both superoxide and its metabolite H(2)O(2) provide a substantial suppressive effect against EAE in the optic nerve that may be a new therapeutic strategy for suppression of optic neuritis and multiple sclerosis.