Is a polymorphism in the DNA repair domain of APEX1 associated with the radiation-induced pneumonitis risk among lung cancer patients after radiotherapy?
rs1130409 of APEX1 can be a predictor of RP grades ≥3 among patients with lung cancer.
These findings indicate that significant suppression of IL-6 and IL-8 expressions in LPS-stimulated BEAS-2B cells by OGE may be attributed to inhibiting activation of MAPKs and Akt and consequently suppressing nuclear translocation of NF-κB.