Does [ A fragment of collagen XVIII inhibit angiogenesis ]?
The physiological processing of collagen XVIII to endostatin may represent a local control mechanism for the regulation of angiogenesis. The outcome of ongoing clinical trials will determine the role of endostatin as a possible angiogenesis-inhibiting drug in the future.
These data demonstrate that chronic exposure to morphine unexpectedly results in a profound and persistent cardioprotective phenotype.