Does meta-analysis of hepatitis C virus vaccine efficacy in chimpanzees indicate an importance for structural proteins?
The inclusion of nonstructural proteins in HCV vaccines might be detrimental to protective immune responses, and/or structural proteins might activate T-cell responses that mediate viral clearance.
Proposed 12-lead ECG features for differentiation of epicardial versus endocardial sites for nonischemic LV-VTs do not reliably identify VTs that require ablation from the epicardium. Endocardial mapping should be the first approach to catheter ablation for VTs in patients with ischemic heart disease.