Are the panicogenic effects of cholecystokinin-tetrapeptide antagonized by L-365,260 , a central cholecystokinin receptor antagonist , in patients with panic disorder?
These data suggest that CCKB receptors are an important site of action of exogenous CCK-4. It will be important to determine in future studies the efficacy of CCKB receptor antagonists as antipanic agents.
Our study revealed the importance of the IL-1 signaling pathway and a prominent signature of innate immunity and cell migration in the acute phase of the illness.