Is the effect of low birth weight on cardiovascular mortality mediated through high blood pressure?
The inverse association between birth weight and mortality from circulatory diseases in men aged 50-75 years is independent of adult sociodemographic characteristics, smoking and adult obesity and does not seem to be mediated through an increased blood pressure in those with low birth weight.
This exhaustive and highly sensitive assay did not show differences in the genomic expression profile of these two products under the assayed experimental conditions. These results suggest that this technology might be useful for the initial comparison of biosimilars, being part of a comprehensive comparability program that includes clinical testing.