Is the flow cytometric pattern of CD34 , CD15 and CD13 expression in acute myeloblastic leukemia highly characteristic of the presence of PML-RARalpha gene rearrangements?
Our results show that immunophenotyping may be of great value for quick screening of APL with PML/RARalpha rearrangements.
Action potential configuration may influence the reverse rate-dependent APD prolongation due to the intrinsic properties of I(Kr) and I(K1) currents. Drugs lengthening repolarization by decreasing repolarizing outward, or increasing depolarizing inward, currents are expected to cause reverse rate-dependent APD lengthening with high probability, regardless of which current they modify.