Are gene polymorphisms and febrile neutropenia in acute leukemia -- no association with IL-4 , CCR-5 , IL-1RA , but the MBL-2 , ACE , and TLR-4 associated with the disease in Turkish patients : a preliminary study?
Although TLR-4, ACE, and MBL-2 GPs have been extensively investigated in different clinical pictures, this is the first study to evaluate the role of these polymorphisms in the genetic etiopathogenesis of FN in patients with ALs. As a conclusion, TLR-4, ACE, and MBL-2 genes might play roles in the genetic etiopathogenesis of FN in patients with ALs.
In the rat model, vitamin C suppressed alveolar bone resorption, induced by high dietary cholesterol, by decreasing the oxidative damage of periodontal tissue.