Does significant elevation of carcinoembryonic antigen levels in abdominal drain after colorectal surgery may indicate early anastomotic dehiscence?
Significant elevation of CEA levels in abdominal drains in the early postoperative period may indicate early anastomotic dehiscence.
This preliminary study suggests that: an increase in EGFR copy number may be associated with cetuximab response but is a rare event in CRC, KRAS mutations are associated with low response rate but do not preclude any cetuximab-based combination efficacy and EGFR exon 13 variant (R521K) may predict for cetuximab benefit.