Does integrated sequence and expression analysis of ovarian cancer structural variants underscore the importance of gene fusion regulation?
Collectively our results are consistent with the view that gene fusions and other SVs can be significant factors in the onset and progression of ovarian cancer. The results further indicate that it may not only be the occurrence of these variants in cancer but their regulation that contributes to their biological and clinical significance.
The result of this study indicates that the overweight and obesity epidemic among Swedish pre-school children may be levelling off.