Are inflammation and disease activity associated with high circulating cardiac markers in rheumatoid arthritis independently of traditional cardiovascular risk factors?
HS-cTnT and NTproBNP are increased in patients with RA, independent of CV risk factors. The association between HS-cTnT, NT-proBNP, and CRP, together with the correlation between HS-cTnT and disease activity, support the link between myocardial injury/dysfunction and inflammation.
The protective effects of carvedilol, via its antioxidant effect, may have therapeutic potential in patients with iron overload.