Is a common variant in the PNPLA3 gene a risk factor for non-alcoholic fatty liver disease in obese Taiwanese children?
The variant PNPLA3 rs738409 genotypes increased the risk of NAFLD in our population of obese Taiwanese children. The effect of the G allele on pediatric NAFLD followed a dominant genetic model.
ProteinChip technology together with adapted computer based data mining tools are useful for the rapid establishment of potential protein biomarkers.