The use of the score for neonatal acute physiology-perinatal extension (SNAPPE II) in perforated necrotizing enterocolitis: could it guide therapy in newborns less than 1500 g?
The modified SNAPPE score is a good predictor of mortality after the PD insertion. A post-PD insertion, high SNAPPE value was correlated with increased mortality regardless of an additional laparotomy. External validation of the modified SNAPPE score in a large patient population is required before its use in guiding treatment decisions.
These data show breast milk HIV-gag-specific IFN-γ cellular immune responses are prevalent and may contribute to protection from early HIV transmission. More broadly, these data suggest breast milk cellular responses are potentially influential in decreasing mother-to-child transmission of viruses.