Does AIDS impair the absorption of antituberculosis agents?
There was no evidence that HIV infection reduced the plasma concentrations of antituberculosis drugs.
Nek2 plays a central role in proteasome-mediated cell cycle regulation and in conferring resistance to bortezomib in cancer cells. Taken together, our results introduce Nek2 as a therapeutic target in bortezomib-resistant multiple myeloma.