Do gain-of-function mutations in the K ( ATP ) channel ( KCNJ11 ) impair coordinated hand-eye tracking?
These results identify impaired hand-eye coordination as a new clinical feature of iDEND. The aetiology of this feature is likely to involve cerebellar dysfunction. The data further suggest that sulphonylurea doses that control the diabetes of these patients may be insufficient to fully correct their neurological symptoms.
These data suggest inappropriate isotretinoin utilization, even more so after guidelines were promulgated.