Does helicobacter pylori-induced atrophic gastritis progressing to gastric cancer exhibit sonic hedgehog loss and aberrant CDX2 expression?
Loss of sonic hedgehog expression and aberrant expression of CDX2 correlates with the type of intestinal metaplasia and may play a role in carcinogenesis.
FGF-20, having demonstrated therapeutic activity in 2 experimental models of intestinal inflammation, represents a promising new candidate for the treatment of human inflammatory bowel disease.