Does age influence circulating adhesion molecules in the critically ill?
The higher plasma concentrations of the measured adhesion molecules in elderly critically ill patients indicate that elderly patients are more prone than younger patients to a more pronounced activation or even damage of the endothelium. Further work needs to be done to determine the prognostic importance and to define the role of soluble adhesion molecules, particularly in the elderly critically ill patient.
APC-wt status is a marker of poor prognosis in MSS proximal colon cancer.