Does paternal transmission of MTHFD1 G1958A variant predispose to neural tube defects in the offspring?
Our research provides the first evidence supporting a paternal, rather than a maternal, transmission bias of MTHFD1 G1958A variant for NTD susceptibility in the offspring.
HIGH CRF is associated with lower levels of total and abdominal obesity for a given BMI by comparison to those with LOW CRF, independent of gender. This finding suggests a mechanism by which exercise attenuates the health risks attributed to obesity as measured by BMI. It is suggested that the routine measurement of WC and CRF would substantially improve the ability to identify those at health risk.