Is androgen deprivation therapy for prostate cancer associated with cardiovascular morbidity and mortality : a meta-analysis of population-based observational studies?
ADT is associated with both CVD and CVM. Particularly, GnRH alone and GnRH plus AA can significantly increase the incidence of cardiovascular events in patients with PCa.
PB attenuates neurological deficits and BBB disruption in a rat model of cerebral ischemia, and the neuroprotection of PB is associated with activation of NF-E2-related factor pathway.