Does the use of linked seeds eliminate lung embolization following permanent seed implantation for prostate cancer?
No evidence of seed embolization was observed with the use of stranded (125)I seeds as used for prostate brachytherapy.
Concomitant inhibition of MET and PKCbeta significantly increased cytotoxicity in vitro against NSCLC, disrupting important downstream signaling pathways. Further evaluation in animal models is warranted.