Is coronary collateral circulation less developed when ischaemic heart disease coexists with diabetes?
Patients with IHD and diabetes have less developed coronary collateral circulation than IHD patients without diabetes, regardless of the extent of coronary lesions. Patients with diabetes who undergo coronary angiography, have more advanced coronary atherosclerotic lesions than patients without diabetes.
HG impairs brain microvascular endothelial function through involvements of oxidative stress and several signal transduction pathways.