Is reverse remodelling through exercise training more pronounced in non-ischemic heart failure?
This post hoc analysis shows that training intervention is associated with significant reverse remodelling in NHF, but not in IHF patients, whereas V(O)(2) peak and muscle volume improve regardless of CHF aetiology. Future prospective studies are needed to confirm our findings.
This suggests that UPR induction agents may be potentially useful response modifying agents in patients undergoing therapy for colorectal cancer.