Are polymorphisms of the IL1-receptor antagonist gene ( IL1RN ) associated with multiple markers of systemic inflammation?
Common functional polymorphisms of the IL1RN gene are associated with several markers of systemic inflammation.
Relative to other lipoproteins, low serum Apo C-III levels are the most strongly associated with chronic versus cleared infection and decline with increasing severity of hepatic fibrosis. Apo C-III deserves further attention as a possible marker of HCV disease progression.