Is the hemostatic activity of cryopreserved platelets mediated by phosphatidylserine-expressing platelets and platelet microparticles?
PLT cryopreservation results in the generation of phosphatidylserine-expressing PLT microparticles which contribute to the hemostatic activity. Understanding the hemostatic activity of these components may assist in extending the use of these specialized components beyond military applications.
These findings show that cocaine taking and cocaine seeking evolve differently during abstinence from extended drug use and depend on dissociable neuronal processes in different subregions of the nucleus accumbens.