Is disease-related anemia in chronic lymphocytic leukemia due to intrinsic defects of erythroid precursors : a possible pathogenetic role for tumor necrosis factor-alpha?
We concluded that CLL-related anemia was not due to intrinsic defects of erythroid precursors, but might result from the direct suppressive effect of TNF-alpha on the erythroid production.
Comparing with the alterations at 9q33 to 34.2 regions, LOH at 9q34.3 and methylation of the Notch1 gene was less involved in oral squamous cell carcinomas.