Does growth Hormone deteriorate the Functional Outcome in an Experimental Model of Huntington 's Disease Induced by 3-Nitropionic Acid?
Those results suggest that application of GH to a 3NP-induced experimental model of HD deteriorates the progress of functional deficits, possibly disturbing mitochondrial activities.
The results obtained show a relationship between the decrease of intracellular polyamine content, the rate of cell growth and the cytoskeleton organization.