Is strontium ranelate analgesia in arthritis models associated to decreased cytokine release and opioid-dependent mechanisms?
SR provides analgesia in arthritis that is associated to inhibition of the release of inflammatory cytokines into inflamed joints. This effect is abrogated by administration of the opioid antagonist naloxone.
Retrograde Intrarenal Surgery is an effective and safe surgery with high stone-free rates and low morbidity in patients with different ASA physical status.