Is progenitor marker CD133 mRNA elevated in peripheral blood of cancer patients with bone metastases?
CD133, but not CD146, mRNA expression is increased in cancer patients with metastatic disease, specifically with bone metastasis. In addition, CD133 mRNA expression seems to be an independent prognostic factor for overall survival.
An altered immune response to LPS seems to play a role in the genetic predisposition to CD but not to UC.