Are methylation alterations a major cause of PTTG1 misregulation?
Our data suggest that neither methylation alterations nor LOH are involved in PTTG1 over-expression. These data, together with those previously reported, point towards a post-transcriptional level of misregulation associated to PTTG1 over-expression.
Beat-to-beat QT interval variability is affected by drugs that modulate the autonomic nervous system.