Is soluble tumor necrosis factor receptor 1 associated with diminished estimated glomerular filtration rate in colombian patients with type 2 diabetes?
Elevated levels of sTNFRs, especially sTNFR1, are associated with loss of kidney function in Hispanic patients with DM2. Future studies should focus on social and genetic determinants of inflammation and their association with CKD in this ethnicity.
Despite our small series, the incidence of cancer in patients with DM (25%) is similar to that observed in larger series (15%-30%). All patients presented with cutaneous lesions. Only one of them had also hemoptysis and was diagnosed of lung cancer. The diagnosis of breast cancer was obtained with a control mammography. The mortality rate in these two patients was not higher. The incidence of cancer is higher in older DM patients.