Is platelet dysfunction an early marker for traumatic brain injury-induced coagulopathy?
These data indicate that early platelet dysfunction is prevalent after severe TBI, can be measured in a point-of-care setting using TEG/PM, and correlates with mortality. The mechanism responsible for this platelet dysfunction and associated implications for TBI management remains to be defined.
Glucosaminic acid-cobalt chelate was effective as an antidiabetes agent; its efficacy was proportional to treatment period .The chelated form expressed much less toxicity compared to cobalt only, and stimulated subsequent food intake after daily administration.