Does hormone replacement therapy increase the risk of cranial meningioma?
Long-term HRT use, particularly of combined oestrogen-progestagen therapy, may increase the risk of meningioma.
These data suggest that alcohol requires a soluble cyclase-generated cAMP-PKA pathway that is dependent upon the action of NO to inhibit TACE and TNF-α release. These findings support our observations that alcohol functions through a dual NO and PKA pathway in bronchial epithelial cells.