Is potassium channel dysfunction in cerebral arteries of insulin-resistant rats mediated by reactive oxygen species?
IR induces a type-specific K+ channel dysfunction mediated by reactive oxygen species. The alteration of K(ATP) and BK(Ca) channel-dependent vascular responses may be responsible for the increased risk of cerebrovascular events in IR.
Our results suggest an association between resident level of knowledge and teaching ability. The principal deterrent to teaching--inadequate time--must be addressed to effectively assist surgical resident teaching.