Does cisapride influence cardiac rhythm?
In our study group of children without underlying cardiac disease or electrolyte imbalance, cisapride was found to have no significant effect on cardiac electrical function compared with placebo. These results are consistent with the drug's record of exceedingly infrequent cardiac events. Because the availability of this prokinetic is threatened, its safety and the safety and efficacy of alternative treatment options (including surgery) should be studied further.
Insomnia appears to be a risk factor in the development of back pain in healthy individuals. However, no evidence of reverse causation was found.