Does restoration of PTEN expression alter the sensitivity of prostate cancer cells to EGFR inhibitors?
Our results suggest that signaling cross-talk between the PI3K-Akt and MAPK pathways occurs in CaP cells, highlighting the potential benefit of targeting both the PI3K-Akt and MAPK pathways in CaP treatment.
These findings suggest that RKIP could be a promising marker for predicting a better prognosis in pancreatic cancer.