Do hepatic stellate cells derive from the neural crest?
These findings suggest HSC do not descend from the neural crest, and therefore may derive from the septum transversum mesenchyme, from endoderm or from the mesothelial liver capsule.
Besides the nadir Scr, early neonatal Scr values (peak, days 9-42, PUV cohort-specific 75th centile) also predicted unfavorable renal outcome. The introduction of PUV disease specific reference Scr centiles may be helpful to facilitate earlier prediction and guide counseling, but necessitates external validation.