Does sufentanil inhibit migration of human leukocytes through human endothelial cell monolayers?
Leukocytes play an important role during inflammation, and anesthetics influence leukocyte functions, e.g., respiratory burst or chemotaxis. The effect of sufentanil on transendothelial leukocyte migration has not been investigated. Therefore, we used a migration assay including endothelial cell monolayers. Sufentanil showed a reducing effect on transendothelial leukocyte migration.
The results of this study showed that fur appears to be involved in acid resistant H. pylori urease activity.