Is high intestinal cholesterol absorption associated with cardiovascular disease and risk alleles in ABCG8 and ABO : evidence from the LURIC and YFS cohorts and from a meta-analysis?
High cholesterol absorption is associated with risk alleles in ABCG8 and ABO and with CVD. Harm caused by elevated cholesterol absorption rather than by plant sterols may therefore mediate the relationships of ABCG8 and ABO variants with CVD.
In conclusion, plasma MPO levels were not elevated in patients with stable CAD, suggesting that systemic release of MPO is not a characteristic feature of asymptomatic CAD.