Are tOP1 gene copy numbers increased in cancers of the bile duct and pancreas?
We here report that a substantial number of patients with bile duct or PC have increased TOP1 copy number and increased TOP1/CEN-20 ratio making further analyses on the association between TOP1 gene copy number and irinotecan efficacy clinically relevant.
Disinfection results from multivariate factors and this study confirmed that the lens material and the MPS play a very important role in the disinfection efficacy of CL.