Is mechanical stretch-induced hypertrophy of neonatal rat ventricular myocytes mediated by beta ( 1 ) -integrin-microtubule signaling pathways?
Anti-integrin-beta1-blocking antibody and colchicine had similar effects, partly inhibiting the stretch-induced increase in microtubule polymerization and the secretion of Ang II in hypertrophic cardiac myocytes.
Our results suggest that maternal PCDD/F and BDE-153 body burdens influence maternal TH status in early pregnancy, which is a critical period when maternal TH status influences fetal development.