Are cDKN2A-rs10811661 polymorphism , waist-hip ratio , systolic blood pressure , and dyslipidemia the independent risk factors for prediabetes in a Vietnamese population?
The study suggested that the CDKN2A-rs10811661 polymorphism, waist-hip ratio, systolic blood pressure, and dyslipidemia were significantly associated with the increased risk of prediabetes in a Vietnamese population. The studied genetic variant had a small effect on prediabetes.
Taken together, our study strongly suggests that the NGF signaling system is a potential novel target for treating opioid-induced tolerance.