Does extended haplotype analysis reveal an association of TNF polymorphisms with susceptibility to systemic lupus erythematosus beyond HLA-DR3?
Extended haplotype analysis revealed HLA-DR3 independent associations of TNF polymorphisms with susceptibility to SLE. Haplotypes that have been shown to be associated with different TNF-alpha production capacity may prevail in different disease subgroups.
Variations in disc height may compromise the general conclusions reached from experimental work and analytic studies in which geometric parameters (especially disc height and disc cross-sectional area) are not taken into consideration.