Is time to recurrence a significant predictor of cancer-specific survival after recurrence in patients with recurrent renal cell carcinoma -- results from a comprehensive multi-centre database ( CORONA/SATURN-Project )?
Advanced age, male gender, larger tumour diameters, LVI, Fuhrman grade 3-4, pN + stage, and advanced tumour stages are associated with early recurrence. Up to 4 years from surgery, a shorter TTR independently predicts a reduced CSS after recurrence.
The Sprotte needles have an inherent design weakness to lateral and axial pressure, which may result in a greater number of needle tip deformations upon needle insertion. The nature of this deformation may result in difficulty in needle withdrawal and possibly fracture of the needle tip.