Does transmembrane serine protease TMPRSS2 activate hepatitis C virus infection?
The cell-surface activity of a trypsin-like serine protease, such as TMPRSS2, activates HCV infection at the postbinding and entry stage. Host transmembrane serine proteases may be involved in the sensitivity, persistence, and pathogenesis of HCV infection and be possible targets for antiviral therapy.
The picture provided by the answers is impressive for the patient, improves compliance and makes diagnosis easier. In the same way, one can document the success of therapy and explore individual outcomes which show a resistance to therapy.