Is cytoprotective effect of bismuth subsalicylate in indomethacin-treated rats associated with enhanced mucus bismuth concentration?
Bismuth accumulation in the gastric mucus during the evolution of mucosal injury may play an important role in the gastroprotective effect of bismuth subsalicylate against indomethacin injury.
These results demonstrate that the death of osteoarthritic chondrocytes is an apoptotic phenomenon which is preceded by an accelerated mechanism of replicative senescence.