Are vitamin D receptor gene polymorphisms associated with increased risk and progression of renal cell carcinoma in a Japanese population?
The AA genotype at the ApaI site of the VDR gene may be a risk of incidence and poor prognosis factor for RCC in the Japanese population. Additional studies with a large sample size and investigation of the functional significance of the ApaI polymorphism in RCC cells are warranted.
Deer femora should be considered a suitable animal model for the human femur.