Is lidocaine contact allergy becoming more prevalent?
The proportion of ACD caused by lidocaine is higher than expected. This is likely secondary to an increase in OTC medicaments containing lidocaine. Patients who are patch test-positive to a local anesthetic should be challenged intradermally to confirm clinical relevance. Because ACD is a delayed Type IV hypersensitivity reaction (localized dermatitis), the risk of anaphylaxis is not a concern.
The data suggested that the cationic EGCG-loaded nanoliposomes would be a good choice for the treatment of MRSA infections due to its high effectiveness.