Does ibuprofen combined with antibiotics suppress renal scarring due to ascending pyelonephritis in rats?
Renal scarring resulting from acute pyelonephritis in this rat model is not decreased by delayed treatment with antibiotics only. The addition of ibuprofen to antibiotic therapy is effective for decreasing renal scarring due to acute pyelonephritis even when treatment is delayed for 72 hours.
Our data suggested that FGFR4 might induce NPC progression and act as a potential therapeutic target in NPC.