Does in vivo T-cell depletion enhance production of anti-GALalpha1,3GAL natural antibodies in alpha1,3-galactosyltransferase-deficient mice?
In vivo T-cell depletion facilitates anti-Gal IgM production, suggesting that T cells deliver inhibitory signals to B cells responding to Gal.
The factors that predict a pCR after neoadjuvant treatment for rectal cancers are absence of circumferential involvement and signet ring cell histology. Pathological complete response may confer an insignificant survival advantage.