Is s100B protein in serum elevated after global cerebral ischemic injury?
The level of S100B protein in serum is elevated after ischemic brain injury, but its mechanism is unclear.
In this model of short-term hibernation, glucose and lactate uptake increase relative to oxygen consumption during sustained ischemia, and temporally coincide with the recovery of bioenergetics. The findings are consistent with the notion that glycolytically derived ATP is important for the maintainance of energy supply during sustained ischemia.