Does heparin attenuate lipopolysaccharide-induced acute lung injury by inhibiting nitric oxide synthase and TGF-β/Smad signaling pathway?
Heparin significantly ameliorated the lung injury induced by LPS in rats via the inhibition of nitric oxide synthase expression and the TGF-β/Smad pathway. Heparin may be a potential therapeutic reagent for treating ALI in the future.
Re-ISBT increased the vaginal mucosal reaction, as shown by increased erythema and ulceration, more than initial brachytherapy, with a higher cumulative radiation dose, but the reaction was mild in almost all cases.