Does autotaxin activity have a high accuracy to diagnose intrahepatic cholestasis of pregnancy?
Increased serum autotaxin activity represents a highly sensitive, specific and robust diagnostic marker of ICP, distinguishing ICP from other pruritic disorders of pregnancy and pregnancy-related liver diseases. Pregnancy and oral contraception increase serum autotaxin to a much lesser extent than ICP.
Children and adolescents with suicide attempt had previous psychopathological antecedents and important mental disorders such as depression and conduct disorder, which require adequate treatment and sanitary control, in order to avoid more severe consequences. The most used method to attempt suicide was ingestion of psychotropics.