Do fetal membranes inhibit prostaglandin but not oxytocin-induced uterine contractions?
Fetal membranes inhibit agonist-induced uterine contractions. The fetal membrane inhibitory system is agonist selective.
These results demonstrate that the potency and specificity of sildenafil as an inhibitor of ABCB1 and ABCG2 is not sufficient to warrant further clinical testing of this agent in combination with anticancer drugs.