Is t-wave inversion on electrocardiogram related to the risk of acute coronary syndrome in the general population?
TWI has a strong and independent predictive value for ACS in the general population.
We have found that rs3745367 and rs1423096 on the RETN gene were significantly associated with resistin levels. However, rs1423096, downstream of RETN, seems to be associated with MetS and T2DM risk more so than rs3745367. The established genotype-disease association points to a causal association of resistin and T2DM.