Does cirrhosis induce apoptosis in renal tissue through intracellular oxidative stress?
These results indicate that intracellular increase of ROS cause damage in the DNA and apoptosis getting worse the renal function in cirrhosis.
In this series of allograft nephrectomies, SIGEI was significantly associated with vascular rejection (Banff type II) but not with risk of allergic iatrogenic nephritis, suggesting that the presence of SIGEI may be a helpful criterion in the pathologic diagnosis of renal allografts.