Is grb2 required for atherosclerotic lesion formation?
Grb2 is required for atherosclerotic lesion formation and uptake of oxidized LDL by macrophages.
The data suggest that nutrition support influences either the distribution of TNF or the FCR, resulting in a greater retention in the plasma-associated compartment with intact absolute removal rates. This study has important implications concerning the type of nutrition support provided to the critically ill patient because our data suggest that clinical states with increased circulating TNF levels may be adversely affected by currently available nutritional practices.