Does interleukin-1 receptor antagonist alter the response to vessel wall injury in a porcine coronary artery model?
IL-1ra was associated with a sustained, significant reduction in neointima after vessel wall injury as long as it is given for the duration of the stimulation of the IL-1 system, in this case at least 28 days. This suggests that therapies based on the antagonism of IL-1 may modulate the coronary artery response to injury.
There are three major reasons for the development of SB: some patients do not come for an examination because there is no discomfort, the second reason is that the medical treatment at the first visit was too superficial and thirdly a small foreign body may also be overlooked due to deficient or inappropriate methods of examination. Therefore, sporadic cases of SB are still to be expected in the future.