Are posterior pituitary functions altered after growth hormone replacement therapy in hypopituitarism due to Sheehan 's syndrome?
Patients with SS have subtle abnormalities in posterior pituitary functions and the threshold for thirst perception is increased. However GH replacement therapy does not seem to reverse or adversely affect the mildly deteriorated posterior pituitary functions of SS patients.
It can be concluded that some of the neoclassical canons can be considered still valid, while others seem to be changed over centuries. In particular it seems that relatives reductions in facial medium third, in nose dimensions and in distance between eyes have occurred as well as relative enlargement of eyes and mouth width.