Do early-life stress and antidepressants modulate peripheral biomarkers in a gene-environment rat model of depression?
Lipid metabolism and immunity proteins were differently expressed in FSL in comparison with FRL. Exposure to MS induced changes in inflammation and transport proteins which became apparent in response to antidepressant treatments. Modulated proteins could suggest biomarker studies in humans.
High serum homocysteine and low folate levels are associated in Turkish men independently with CHD, which needs confirmation in a larger sample. In women, vitamin B(12) concentrations are significantly associated with MS likelihood.