Overdiagnosis in screening: is the increase in breast cancer incidence rates a cause for concern?
There is a small amount of overdiagnosis of ductal carcinoma in situ in mammography screening; however, this should not deter women from being screened. Training and practice in mammographic screening should emphasise detection of small, invasive lesions. Research into the natural history and treatment of the disease should aim at minimising overtreatment of those in situ lesions that are less likely to progress to invasive disease.
HB vaccination can not enhance anti-HBs levels in those with positive serum anti-HBs and anti-HBc markers.