Is synuclein-γ ( SNCG ) expression in ovarian cancer associated with high-risk clinicopathologic disease?
SNCG expression in ovarian cancer is frequent in patients with high-risk features, but it does not correlate with chemotherapy response, overall survival, or progression-free survival.
If confirmed, the STRAP gene copy status might provide a parameter to decide about the use of 5-FU-based adjuvant chemotherapy.