Does recombinant Human Alpha-1 Antitrypsin-Fc Fusion Protein reduce Mouse Myocardial Inflammatory Injury After Ischemia-Reperfusion Independent of Elastase Inhibition?
The pAAT and recombinant human AAT-Fc reduce the acute myocardial inflammatory injury after ischemia-reperfusion in the mouse leading to preservation of viable myocardium and systolic function, independent on the effects on neutrophil elastase.
HER2 status was the only primary tumor characteristic that correlated with the presence of CTCs. Long-term follow-up will be required to determine the significance of CTCs in operable breast cancer.