Is transient increase of cytokines in the acute ischemic tissue beneficial to cell-based therapeutic angiogenesis?
A transient increase of cytokines in the acute ischemic tissue is beneficial for cell-based therapeutic angiogenesis.
ERK5 is present in RGCs. Retina and brain p-ERK5 levels develop differently with age. The response of ERK5 but not ERK1/2 to BDNF stimulation or inhibition at the RGC axon ending indicates that retrograde neurotrophic signals in the rat optic nerve may be mediated by the ERK5 pathway.