Does a Lentiviral Vector Expressing Japanese Encephalitis Virus-like Particles elicit Broad Neutralizing Antibody Response in Pigs?
Immunization of pigs with the lentiviral vector expressing JEV virus-like particles is particularly efficient to prime antigen-specific humoral immunity and trigger neutralizing antibody responses against JEV genotypes 1, 3, and 5. The titers of neutralizing antibodies elicited by the TRIP/JEV vector are sufficient to confer protection in domestic pigs against different genotypes of JEV and this could be of a great utility in endemic regions where more than one genotype is circulating.
IPP is a useful predictor for evaluating the success of a voiding trial following ARU. Patients with a grade 1 prostate may benefit from a trial without a catheter. However, patients with a grade 3 prostate are less likely to do so and would require a more definitive surgical procedure.