Are anti-cytomegalovirus antibody levels associated with carotid atherosclerosis and inflammatory cytokine production in elderly Koreans?
These findings may provide insight into the role of HCMV in the pathogenesis of atherosclerosis and chronic inflammation in elderly individuals.
Extravasated fibrinogen might play an important role in the development of choroidal neovascularization associated with age-related macular degeneration, at least in part, through the function of VEGF in an autocrine manner. Transcription factor HIF-1 appears to be involved in fibrinogen-induced VEGF expression.