Are areas of interictal spiking associated with metabolic dysfunction in MRI-negative temporal lobe epilepsy?
Metabolic dysfunction is present in focal areas of interictal spiking in nonlesional temporal lobe epilepsy. These findings confirm that functional abnormalities can be detected in vivo in radiographically normal-appearing cortex exhibiting abnormal excitability.
Adriamycin-induced increased expression of FN, in the ARM, may contribute to abnormal notochord development leading to the VACTERL association.