Does allergic sensitization through the airway prime Th17-dependent neutrophilia and airway hyperresponsiveness?
Allergic sensitization through the airway primes modest Th2 responses but strong Th17 responses that promote airway neutrophilia and acute AHR. These findings support a causal role for neutrophils in severe asthma.
Osteoprotegerin is an independent risk factor for the progression of atherosclerosis and onset of cardiovascular disease.