Do complement C1Q polymorphisms modulate onset in familial amyloidotic polyneuropathy TTR Val30Met?
Our study has identified polymorphisms which may influence the FAP-TTR Val30Met phenotype. Identifying modifier genes and their protein products may contribute to therapeutic advances.
In spite of local medical therapy and stabilization of IOP values, in advanced stages of glaucoma, the progression of the disease occurred. The 3 years follow up period was too short to reveal any significant changes in the ONH topography in the group with ocular hypertension. HRT II was a reproducible method in the follow up of structural changes of the ONH in all evaluated groups.