Is ochratoxin A detectable in renal and testicular tumours?
The OTA levels detected in the serum of patients were highly variable and relatively low. No OTA was detected in the tissue samples.
These results demonstrated that expression of ERalpha, p-ERalpha, NF-kappaB p65 and MMP-9 correlated with invasion and metastasis in HCC. The mechanism of HCC metastasis may mediate through cross-talk between the NF-KB and ER signaling pathways. Meanwhile, ERa regulated MMP-9 through NF-kappaB indirectly.