Are cC chemokine and CC chemokine receptor profiles in visceral and subcutaneous adipose tissue altered in human obesity?
Up-regulation of the CC chemokines and their respective receptors in adipose tissue occurs in human obesity and is associated with increased systemic inflammation.
Coronary endothelial dysfunction and hyperlipidemia are independently associated with impaired relaxation in patients with normal ejection fraction in the absence of occlusive CAD and heart failure. The current study suggests a new potential mechanism for the development of endothelial and diastolic dysfunction in humans.