Does nonmuscle myosin II generate forces that transmit tension and drive contraction in multiple tissues during dorsal closure?
We establish that zip/MyoII is responsible for generating the forces that drive cell-shape changes in each of the force-generating tissues that contribute to closure. This highly conserved contractile protein likely drives cell-sheet movements throughout phylogeny.
There are no associations between preoperative lateral subluxation of the native menisci and postoperative subluxation of meniscal transplants in patients who undergo MAT on the lateral compartment with low-grade arthritic changes. The extrusion phenomenon may be a distinct feature of transplanted menisci rather than an individual characteristic of meniscal displacement. Surgeons need to keep in mind that graft extrusion in nonarthritic knees might occur during transplantation.