Do antiretroviral treatment interruptions predict female genital shedding of genotypically resistant HIV-1 RNA?
Treatment interruption >48 hours during nonnucleoside reverse transcriptase inhibitor-based therapy led to a significantly increased risk of detecting genotypically resistant HIV-1 RNA in female genital tract secretions. Patient- and program-level interventions to prevent treatment interruptions could reduce the risk of shedding-resistant HIV-1 during ART.
The study suggests that krill oil may be a useful intervention strategy against the clinical and histopathological signs of inflammatory arthritis.