Does increased short-term variability of repolarization predict d-sotalol-induced torsades de pointes in dogs?
Proarrhythmia is not related to differences in prolongation of repolarization but corresponds to BVR, here quantified as STV of the left ventricle. STV could be a new parameter to predict drug-induced TdP in patients.
This study supports previous findings that raised BMI, which is likely associated with increased number of adipocytes, may contribute to increased cytokine serum concentrations in females.