Does colitis affect the smooth muscle and neural response to motilin in the rabbit antrum?
Colitis altered the course of the motilin-induced smooth muscle contraction in the antrum. This involved changes in the kinases phosphorylating MLC. Increased cholinergic excitability to motilin in the antrum may play a role in the pathogenesis of inflammation-associated gastric motility disorders.
Histamine was positively correlated with fibrosis and may be a potential target to prevent liver fibrosis in BA.