Does a Low Neutrophil CD64 Index be Associated with Sustained Remission During Infliximab Maintenance Therapy?
Neutrophil CD64 index >1 is a significant risk factor for treatment failure during infliximab maintenance therapy.
The synergistic induction of COX-2 by AngII and IL-1β in VSMCs involves HuR through an ERK1/2-dependent mechanism. The HuR/COX-2 axis participates in cell migration and vascular damage. HuR might be a novel target to modulate vascular remodelling.