Is fresh frozen plasma independently associated with a higher risk of multiple organ failure and acute respiratory distress syndrome?
In patients who survive their initial injury, FFP was independently associated with a greater risk of developing MOF and ARDS, whereas CRYO was associated with a lower risk of MOF. Further investigation into the mechanisms by which these plasma-rich component transfusions are associated with these effects are required.
Our results show that the mitochondrial redox state and electron transport activity can be restored by reducing HCV replication.