Is bacterial vaginosis associated with prematurity and vaginal fluid mucinase and sialidase : results of a controlled trial of topical clindamycin cream?
Persistence of sialidase-producing vaginal microorganisms in numbers sufficient to increase vaginal fluid sialidase activity may be a risk factor for possibly preventable subclinical intrauterine infection and preterm birth. This study confirms and further informs our understanding of the association of bacterial vaginosis and preterm birth; studies to evaluate whether systemic treatment for bacterial vaginosis can effectively reduce vaginal mucolytic enzymes and risks of prematurity and other morbid outcomes are continuing.
The expression pattern of hPEBP4 indicated that hPEBP4 interacted with ER and PR in EEC and could thus become a possible target for the development of novel treatment against this malignancy.