The monocyte/IgE connection: may polymorphisms in the CD14 gene teach us about IgE regulation?
Our results highlight the complex role played by monocytes in IgE regulation.
Rilmenidine has a remarkable role in NO-defective hypertension, possibly by inhibiting central sympathetic outflow and by affecting receptors in vascular smooth muscle also. The prime cause of hypertension in this experimental model--the compromised production of NO due to inhibition of NOS--was not affected by rilmenidine.