Intergenerational relations for drinking motives: invariant for same- and opposite-sex parent-child dyads?
Intergenerational factors contributing to alcohol phenotypes may not be limited to the modeling of alcohol use or the occurrence of alcohol disorders but may also include cognitive-motivational systems of affective regulation related to the use of alcohol. Future research would benefit by focusing on how biogenetic and socialization factors contribute to same- and opposite-sex intergenerational patterns and how to use this information to strengthen intervention programs.
Long-term presence of high glucose induced STAT3 mediated ICAM-1 dependent endothelial adhesiveness to monocytes via the osmotic-related redox-dependent interleukin-6 pathways. GBE reduced high-glucose-induced endothelial inflammation mainly by inhibiting interleukin-6 activation. Future study is indicated to validate the antioxidant/anti-inflammatory strategy targeting on interleukin-6 for endothelial protection in in vivo and clinical hyperglycemia.