Is the expression of the regulatory T cell-specific forkhead box transcription factor FoxP3 associated with poor prognosis in ovarian cancer?
High expression levels of FoxP3 might represent a surrogate marker for an immunosuppressive milieu contributing to tumor immune escape. Strategies selectively depleting Treg might improve the antitumor activity of endogenously arising tumor-reactive T cells and immunotherapies using vaccines or antibodies.
Freeze-dried gamma irradiated cadaveric fascia lata and acellular cadaveric dermis contained intact DNA.