Is stavudine toxicity in women the main reason for treatment change in a 3-year prospective cohort of adult patients started on first-line antiretroviral treatment in Uganda?
The majority of the treatment changes were due to stavudine-related toxicity. Long-term stavudine use is less well tolerated in women.
Anxiety and depression was associated with more severe aging symptoms in male psychiatric outpatients. Sexual dysfunction could be regarded as the core manifestation to differentiate aging symptoms from syndromal emotional distress.