Are retinal nerve fibre layer measurements reduced in patients with obstructive sleep apnoea syndrome?
The sleep apnoea syndrome is correlated with a proportional decrease in the RNFL. Decreased ocular perfusion related to hypoxia and vasospasm associated with OSAS may cause RNFL thinning, which may precede clinically detectable glaucoma.
Proton pump inhibitor treatment stimulated oxygen-derived free radical production in the corpus mucosa.