Are aspartate aminotransferase to platelet ratio index and sustained virologic response associated with progression from hepatitis C associated liver cirrhosis to hepatocellular carcinoma after treatment with pegylated interferon plus ribavirin?
In HCV-infected cirrhotic patients who received combination therapy, APRI and SVR are the two major predictors of HCC development.
The Val103Ile polymorphism of the MC4R gene is associated with energy expenditure in humans. Furthermore, it may associate with glucose oxidation, free fatty acid levels, and weight gain.