Does core needle biopsy of breast cancer tumors increase distant metastases in a mouse model?
CNB creates an immunosuppressive tumor microenvironment, increases EMT, and facilitates release of CTCs, all of which likely contribute to the observed increase in development of distant metastases.
Intraoperative monitoring of CM thresholds may be valuable for identifying the exact point of time at which residual hearing is affected in CI patients. Opening of the cochlea itself seems to be unrelated to hearing loss. A significant proportion of patients may have hearing loss caused by secondary effects rather than a direct trauma.