Is epstein-Barr virus infection predictive of CNS involvement in systemic AIDS-related non-Hodgkin 's lymphomas?
These results show that EBV infection of the tumor clone significantly increases the risk of CNS involvement by systemic AIDS-NHL, without regard of specific molecular features. The detection of EBV-DNA in the CSF of AIDS-NHL patients may select cases with higher risk of CNS involvement and, therefore, may prove useful in the therapeutic stratification of these tumors.
The C2 pedicle screw is a good technique for osteosynthesis. However, the claimed long term advantage of motion segment preservation with this technique remains doubtful. It may be suitable for those fractures with minimal translation (<4mm), where the superiority of surgery, itself, over external immobilization is questionable. C2-3 fusion is preferable for those fractures with translation>4mm as these are unstable and C2 pedicle screws alone are likely to have less desirable results.