Does magnetic resonance spectroscopy suggest key differences in the metastatic behaviour of medulloblastoma?
Metastatic medulloblastomas have metabolite profiles indicative of increased cell growth and decreased cell death compared with localised tumours reflecting intrinsic differences in underlying biology. Localised tumours with an MRS metabolite profile similar to those with metastatic disease may be at increased risk of metastatic relapse.
These data indicate that homelessness and associated high-risk sexual practices may be indications for prevaccination screening for HBI in adolescents.