Are cXCL1-deficient mice highly sensitive to pseudomonas aeruginosa but not herpes simplex virus type 1 corneal infection?
The absence of CXCL1 and CXCL2 expression significantly impairs the ability of the host to control P. aeruginosa replication through the recruitment of leukocytes to the central cornea. In contrast, CXCL1, CXCL2, and the cells they recruit, are not required for HSV-1 clearance during acute infection.
Symptoms appear to be useful for discriminating IBS from organic gastrointestinal disease and food allergy.