Does p2X7 receptor activation mediate retinal ganglion cell death in a human retina model of ischemic neurodegeneration?
These studies demonstrated that stimulation of the P2X7R can mediate RGC death and that this mechanism plays a role in ischemia-induced neurodegeneration in the human retina.
Although the prevalence of SO increased, the cardio-metabolic profile remained stable. Nevertheless, regular monitoring of chronic disease in this population remains crucial.