Should anticoagulant therapy be stopped or reversed before venous intervention?
Venous intervention in patients receiving therapeutic anticoagulation is safe, with no complications reported in our series. There is no need to discontinue anticoagulant therapy in patients with life-threatening thrombo-embolic disease. Real-time sonographic guidance greatly facilitates venous cannulation and avoids inadvertent arterial puncture.
A modified cryopreservation technique preserves endothelial function independently of the storage time up to 6 months.