Does reduced vital capacity lead to exercise intolerance in patients with ankylosing spondylitis?
Rather than musculoskeletal manifestations, exercise intolerance was mainly explained by pulmonary function impairment in AS patients.
The giant cells in this case of PVNS express all the phenotypical features of osteoclasts including the ability to carry out lacunar resorption. This may account for the bone destruction associated with this aggressive synovial lesion.