Is the corneal contour influenced by a tension in the superficial epithelial cells?
A tension between the superficial epithelial cells could explain these phenomena. The balance between the pressure exerted by the superficial cell layer under tension and the epithelial growth pressure might be the factor determining the thickness of the epithelium an any point of the cornea in steady state conditions. A preliminary mathematical model and consequences for refractive surgery are presented.
ZAP-70 was found to be expressed in the CD34+ normal bone marrow compartment including earlier B-cell progenitors, but not in CD34- pre-B and immature B cells. By contrast, ZAP-70 was consistently expressed and phosphorylated in Blin-ALL cells. Further studies are required to determine whether ZAP-70 may play a pathophysiological role in Blin-ALL.