Does a compression bandage improve local infiltration analgesia in total knee arthroplasty?
A compression bandage is recommended to improve analgesia after high-volume local infiltration analgesia in total knee arthroplasty.
A single dose of methylene blue seems to be a potent approach to norepinephrine-refractory vasoplegia after cardiopulmonary bypass for most patients, with no obvious side effects. Guanylate cyclase inhibitors could be a novel class of agents for the treatment of norepinephrine-refractory vasoplegia after cardiopulmonary bypass. A controlled clinical trial is now needed to evaluate the role of methylene blue in this situation.