Do chromosomal high-polysomies predict tumour progression in T1 transitional cell carcinoma of the bladder?
Our findings suggest a possible prognostic significance of highly aneuploid cells (high-polysomies of chromosomes 8, 9 and 17) in tumour progression of T1 TCC bladder tumours. FISH analysis is a reproducible technique for evaluating cytogenetic alterations and could contribute to the assessment of the individual prognosis of T1 transitional cell carcinoma of the bladder.
Associations between exposure to organic solvents and EMFs, and Ph+CML were indicated but were not entirely consistent.