Is the improvement of walking abilities and endothelial function after the supervised training treadmill program ( STTP ) in patients with peripheral artery disease ( PAD ) related to prostacyclin and thromboxane release?
STTP in patients with PAD showed significantly improved walking abilities and endothelial function. Lactate production, TXB2 release, and PGI2 release are not directly correlated with improvement of endothelial function and walking abilities. Patients with better-walking abilities at baseline derive greater clinical and metabolic benefits from STTP.
This study revealed that the three web-based predictors equally perform well at the population level, but exhibit a high degree of discordance in the intermediate and poor prognosis groups.