Is the mechanism of preventive effect of captopril on renal ischemia reperfusion injury independent of ATP dependent potassium channels?
It seems that the preventive effect of captopril is not directly mediated by K(ATP) channels and further attention should be paid to other receptor-mediated angiotensin II effects.
PT is a safe and easy procedure and a less invasive alternative to surgical tracheostomy even in small infants. We strongly recommend PT done by Griggs technique in children. It is important that it should be done in an operating room setting and under rigid bronchoscopic guidance.