Does jun N-terminal kinase inhibitor block angiogenesis by blocking VEGF secretion and an MMP pathway?
Our results indicate JNK-I to have a direct anti-atherogenic effect in SMCs and ECs.
Concomitant cholecystectomy can be performed safely in most patients during laparoscopic gastric bypass and does not prolong hospital stay. As such, it is an acceptable form of prophylaxis against stones forming during rapid weight loss. Whether it is superior to chemical prophylaxis remains to be demonstrated in a large prospective randomized study.