Does genome-wide analysis of hepatic fibrosis in inbred mice identify the susceptibility locus Hfib1 on chromosome 15?
The set of inbred strains provides a framework for systematic analysis of fibrogenic genes. QTL mapping is useful to identify genetic susceptibility loci for hepatic fibrosis that might harbor new molecular targets for antifibrotic drug design.
Pantoprazole appears to be superior to ranitidine in gastric ulcer healing.