Methylphenidate reduces energy intake and dietary fat intake in adults: a mechanism of reduced reinforcing value of food?
MPH reduced overall energy intake with a selective reduction in dietary fat. Findings are consistent with a reward deficiency model of obesity whereby low brain dopamine predicts overeating and obesity, and administering agents that increase dopamine results in reduced feeding behavior.
The PQ-induced lung injury was attenuated by artesunate treatment. IL-10, TNF-α, and TGF-β1 may play an important role in PQ-induced lung injury, which can be prevented by artesunate treatment.