Does tSU-68 ameliorate hepatocellular carcinoma growth by inhibiting microenvironmental platelet-derived growth factor signaling?
TSU-68 inhibits stromal PDGF signaling activated by cancer cells and suppresses HCC growth.
Expression of COX-2 was associated with poor outcome from pancreatic ductal adenocarcinoma and was independent of tumour stage, grade, or age in multivariate analysis.