Is promyelocytic leukemia ( PML ) gene expression a prognostic factor in ampullary cancer patients?
Our preliminary data suggest PML as a novel prognostic tool for ampullary cancer patients.
Impairment of rod cGMP-gated channel alpha subunit expression leads to photoreceptor and bipolar cell degeneration. These transgenic mice are the first model of retinal degeneration caused by an alteration in the expression of the rod cGMP-gated channel. This model system can be used to test therapies designed to slow or stalled retinal degenerations.