Does hypoxia/reoxygenation stimulate intracellular calcium oscillations in human aortic endothelial cells?
Posthypoxic reoxygenation stimulates repetitive [Ca(2+)](i) oscillations that are dependent on Ca(2+) release from an intracellular pool and require extracellular Ca(2+) to be maintained. These oscillations may be initiated by NAD(P)H oxidase-derived hydrogen peroxide and may play a role in signal transduction during ischemia/reperfusion in vivo.
A preoperative visit with a radiation oncologist was associated strongly with BCSR use. More should be done to evaluate the role of multidisciplinary consultation in the decision to use BCSR.