Does the microRNA-15 family inhibit the TGFβ-pathway in the heart?
We identified the miR-15 family as a novel regulator of cardiac hypertrophy and fibrosis acting by inhibition of the TGFβ-pathway.
These results show that overweight children find food more reinforcing than do nonoverweight children. This individual difference was replicated in different experiments using different types of foods and food alternatives. These studies provide support for studying food reinforcement as a factor associated with overweight and obesity.