Is sensitization to acrylates a common adverse reaction to artificial fingernails?
Acrylic monomers used when sculpturing ANs are important contact and occupational sensitizers that can produce cross-reactions with other acrylic compounds and trigger allergic reactions when re-exposure occurs in a different setting.
Despite over 90% power to detect a significant odds ratio as small as 1.3, no association was observed. Considering the cumulative evidence from six case-control studies and results from additional family-based studies, it seems unlikely that the 40-base-pair VTNR polymorphism of the SLC6A3 gene influences risk for schizophrenia.