Is [ Chronic muscular pain unexplainable ]?
Chronic muscular pain can be explained by the interaction between body, mind and life circumstances. Searching for simple causalities and consistent findings will provide no benefit. Instead, we should encourage coping strategies with the capacity of breaking vicious circles that maintain symptoms.
In this study, IFN-alpha was found to alter TRP metabolism without inducing psychiatric side effects. Therefore, a possible relationship between TRP metabolism and depression was not substantiated by this study.