Does serum renalase depend on kidney function but not on blood pressure in heart transplant recipients?
Renalase, highly elevated in heart transplant recipients, is predominantly dependent on kidney function, which deteriorates with time after heart transplantation and age. Further studies are needed to establish its putative role in the pathogenesis of hypertension after transplantation and possible novel targeted therapies. However, is seems that among heart transplant recipients renalase was not related to blood pressure.
HLA associations appear to be different in children and adults with SAA. This might point towards a difference in pathophysiology between at least part of the children and adults.