Is change of epigenetic control of cystathionine beta-synthase gene expression through dietary vitamin B12 recovered by methionine supplementation?
Dietary B-12 can affect epigenetic machinery by regulating DNA methylation status and dietary methionine may have small effects on DNA methylation.
Mutations in the genes CFTR, SPINK1, PRSS1, and CTRC do not seem to significantly increase the risk for pancreatic adenocarcinoma.