Does a single application of hydrogen sulphide induce a transient osteoclast differentiation with RANKL expression in the rat model?
H(2)S application caused a transient increase of osteoclast differentiation with up-regulation of RANKL expression in osteoblasts. H(2)S, which is primarily responsible for halitosis, may also contribute to alveolar bone resorption through RANKL expression.
This work suggests that a high prevalence of mosquitoes in late summer is a prerequisite for outbreaks of tularemia in a tularemia-endemic boreal forest area of Sweden and that environmental variables can be used as risk indicators.