Does surfactant protein D inhibit TNF-alpha production by macrophages and dendritic cells in mice?
TNF-alpha can contribute to enhanced SP-D production in the lung indirectly through inducing IL-13. SP-D, on the other hand, can antagonize the proinflammatory effects of TNF-alpha on macrophages and dendritic cells, at least partly, by inhibiting production of this cytokine.
BNP correlated positively with fluid overload measured by HS, and this correlation was stronger in the first 6 months on PD.