Does deregulation of the endogenous C/EBPβ LIP isoform predispose to tumorigenesis?
Elevated C/EBPβ LIP promotes cancer in mice. C/EBPβ LIP is upregulated in B-NHL. Deregulated C/EBPβ LIP alters apoptosis and cytokine/chemokine networks. Deregulated C/EBPβ LIP may support a pro-tumorigenic microenvironment.
We believe that in our population AMT is not a marker for alcoholism, kidney-urinary malformations nor sense organ disorders.