Does soluble tumor necrosis factor receptor abrogate myocardial inflammation but not hypertrophy in cytokine-induced cardiomyopathy?
These results suggest that anti-TNF therapy may hold promise in the treatment of end-stage heart failure.
MeBT is a simple noninvasive method to detect mitochondrial dysfunction in HIV-infected patients that correlates with mtDNA depletion in PBMCs of ART-treated individuals. Decreased hepatic methionine metabolism in therapy-naive patients may reflect the functional relevance of viral-mediated mitochondrial toxicity.