Is anti-angiogenic effect of metformin in mouse oxygen-induced retinopathy mediated by reducing levels of the vascular endothelial growth factor receptor Flk-1?
Metformin exerts anti-angiogenesis effects and delays the normal vessel formation in the recovery phase of OIR in mice, likely by suppressing the levels of Flk1.
This work highlights the interpersonal social context and post-intentional influences on daily health behaviour and offers guidance on the expansion of models of health behaviour as well as potential targets for intervention. Statement of contribution What is already known on this subject? Behavioural intentions are the best predictors of behaviour; however, much variability in actual behaviour remains to be explained. Romantic partners are frequent providers of health-related social support and social control. What does this study add? Provides multidimensional assessment of husband influence. Improves prediction of behaviour using husband influences. Demonstrates moderator of social control on behaviour.