Are polymorphisms in TGFB1 and PDGFRB associated with Moyamoya disease in European patients?
Our results indicate possible genetic risk factors for the genesis of MMD. TGFB1 and PDGFRB are involved in vascular growth and transformation processes which may play a role in the development of MMD. Further analyses in larger European cohorts and replication in patients of different ethnicity, as well as functional studies, may lead to possible early detection of patients at risk for developing MMD and subsequently to future preventive therapies.
Heat-killed Lact. kunkeei YB38 from bee pollen increases IgA production and may safely improve immune responsiveness.