Does an increase in integrin-linked kinase non-canonically confer NF-κB-mediated growth advantages to gastric cancer cells by activating ERK1/2?
An increase in ILK non-canonically promotes ERK1/2/NF-κB activation and leads to the growth of gastric cancer cells.
The BEAR facilitates the use of a variety of resources in answering clinical questions. 69% of users reported at least a small change in clinical practice, suggesting that the BEAR may be a useful tool in evidence-based resident education.