Does hyperhomocysteinemia increase intimal hyperplasia in a rat carotid endarterectomy model?
This is the first study to examine IH after CEA and hyperhomocysteinemia in rats. The study shows that the elevation of serum H(e) levels can be obtained by feeding rats modified diets with added H(e). The consistent elevation of serum H(e) levels was associated with more than 4 times the amount of IH after a CEA in a rat model.
miRNA promoters have similar features to those of protein coding genes, but miRNA transcript organization is more complex.