Does pARP inhibition restore erectile function by suppressing corporal smooth muscle apoptosis in diabetic rats?
Over-activation of penile PARP pathway in diabetic rats enhances corporal apoptosis via energy depletion, suppression of Akt phosphorylation, and activation of the mitochondrial apoptotic pathway, which results in ED; these event could be prevented by treatment with 3-AB.
We concluded that SNP45TG in adiponectin gene is associated with the occurrence of GDM.