Is elm1p one of three upstream kinases for the Saccharomyces cerevisiae SNF1 complex?
Elm1p, Pak1p, and Tos3p are upstream kinases for the SNF1 complex that have partially redundant functions.
Despite the small sample size, our findings suggest that higher plasma TFV trough concentrations may cause TDF-induced renal dysfunction. To prevent TDF-induced renal dysfunction, we propose that individual monitoring of plasma TFV trough concentrations should be performed in Japanese patients with HIV infection.