Is immunoprecipitation of nucleosomal DNA a novel procedure to improve the sensitivity of serum screening for the p16 hypermethylation associated with colon cancer?
IP-MSP is thus considered to be a promising procedure to detect serum methylated DNA in colorectal cancer patients.
Age and ASA-PS scores can predict postoperative morbidity, specific for each operation studied. Assessment of co-morbidity in surgical patients can be accomplished easily and with minimal expense. While remaining budget neutral, the distribution of reimbursements should be based on those preoperative risk factors that predict longer LOS and higher complication rates.