Does renal capsular invasion have any prognostic value in localized renal cell carcinoma?
Tumor diameter and high grade were associated with renal capsular invasion in stage pT1-2 renal cell cancer. However, capsular invasion did not have any independent impact on patient survival.
Surprisingly, our results focused attention on the 'protective' role of a particular virus. CMV is probably capable of triggering some immunomodulating/immune evasion mechanisms which may decrease immune reactivity in MS patients. Further studies are needed to confirm and elucidate our study results on a larger sample of MS patients and in animal model studies.