Is early total white blood cell recovery a predictor of low number of apheresis and good CD34 ( + ) cell yield?
This study shows that it is feasible to mobilise and collect PBPC in patients previously treated with CT with or without RT. There was a linear correlation between the days for WBC recovery and the number of aphereses needed to collect the target number of CD34(+) cells. The study suggests that early WBC recovery, using mainly CY 4 mobilisation chemotherapy, is an important predictor of a low number of aphereses to achieve a good CD34(+) yield.
This suggests that topical application of O-HA could be a useful method by which to treat diabetic wounds in clinical practice.