Is cobalamin measurement overprescribed by physicians?
The significant changes in the volume of Cb assay in recent years are not justified by any new scientific data about new indications for ordering Cb measurement. It seems necessary to establish robust national and international guidelines for inpatient Cb measurement.
Development of AIH in APS-1 is dependent on specific Aire mutations and genetic background genes. Autoimmune response is polyspecific and can be controlled by steroids or transfer with Tregs. This might enable new treatment options for patients with AIH.