Does toll-like receptor 4 signaling lead to neutrophil migration impairment in polymicrobial sepsis?
These results highlight the harmful role of TLR4 signaling in polymicrobial severe sepsis.
The ubiquitin-proteasome degradation pathway contributes significantly to down-regulation of bFGF expression by EGCG. Catechin compounds have fewer adverse effects than chemotherapeutic agents and hence can be used as proof-of-concept in cancer therapeutics to suppress growth and metastasis by targeting proteins such as bFGF.