Do tumor-infiltrating Foxp3-CD4+CD25+ T cells predict poor survival in renal cell carcinoma?
Increased presence of CD4(+)CD25(+)Foxp3(+) T cells was not significantly associated with RCC death. In contrast, CD4(+)CD25(+)Foxp3(-) T cells, which may represent a unique set of Tregs or activated helper T cells, was significantly associated with outcome.
Each of the methods used to model normal fetal weight gain in the third trimester defined a distinct pattern of fetal growth. Normal fetal growth, defined longitudinally, was most closely matched by a combination of cross-sectional ultrasound-derived estimated fetal weight in preterm gestation below 34 weeks' gestation and live birth weight at or beyond 34 weeks.