Is carotid atherosclerosis associated with inflammation and endothelial cell adhesion molecules in chronic haemodialysis patients?
In HD patients, carotid atherosclerosis is associated with inflammation and circulating levels of soluble adhesion molecules ICAM-1 and VCAM-1. The correlations between serum ICAM-1 and IMT and ICAM-1 and survival may indicate that this molecule could be a marker of a process that contributes to the high mortality of HD patients.
Our studies underscore the role of O(2)(-) as a critical regulator of VEGF and PlGF signal transduction initiation in endothelial cells.