Does urothlelium facilitate the recruitment and trans-differentiation of fibroblasts into smooth muscle in acellular matrix?
These data support the hypothesis that epithelial mesenchymal signaling is important for the differentiation of bladder smooth muscle. Smooth muscle development during augmentation with acellular matrix is facilitated by the placement of epithelia onto the surface of the matrix.
The setup for renal perfusion with venous blood during suprarenal clamping was simple and safe. Perfusion significantly reduced the reduction of renal function in the immediate postoperative period, suggesting that clamp time may thus be safely be extended to allow for complex reconstruction of the pararenal aortic segment. The benefit was most marked for patients with preoperative renal impairment.