Does elevated serum IgG4 define specific clinical phenotype of rheumatoid arthritis?
Our results showed that elevated sIgG4 in RA is common and disproportional to total IgG and RA with elevated sIgG4 may be a specific clinical phenotype with higher disease activity, higher level of autoantibodies, and poor response to methotrexate and leflunomide therapy.
CTX-evoked heart failure involves pronounced co-suppression of TrxR1 activity and NPFT level.