Does protein phosphatase 2A contribute to the cardiac dysfunction induced by endotoxemia?
These data support the hypothesis that sustained cTnI phosphorylation underlies the contractile dysfunction seen in sepsis.
Our data suggest that lopinavir-ritonavir salvage therapy led not only to a viral load decrease but also to a phenotypic change. X4 virus appeared to be preferentially suppressed. Shifts in co-receptor usage may thereby contribute to the clinical efficacy of anti-HIV drugs in vertically infected infants.