Does dimethylamino parthenolide enhance the inhibitory effects of gemcitabine in human pancreatic cancer cells?
DMAPT enhanced the anti-proliferative effects of gemcitabine in association with NF-κB suppression in pancreatic cancer cells in vitro. Furthermore, gemcitabine induced NF-κB activity in vivo, thus supporting the evaluation of NF-κB-targeted agents to complement gemcitabine-based therapies.
Intrauterine exposure to maternal infection was associated with a marked increase in the risk of cerebral palsy in preterm infants.