Does heparin bonding improve patency of polytetrafluoroethylene arteriovenous grafts?
hepPTFE AVGs failed to improve patency or decrease secondary interventions compared to standard PTFE grafts. Prospective studies are needed to confirm these results.
TSP-1(-/-) mice had diminished pulmonary vasoconstriction response and were less responsive to hypoxia-induced pulmonary hypertension than their wild type counterparts. This observation suggests that TSP-1 could play an active role in the pathogenesis of pulmonary hypertension associated with hypoxia.