Is inducible cyclooxygenase expression mediating hypoxia/reoxygenation-induced pulmonary vasoconstriction attenuated by a cyclooxygenase inhibitor in rats?
Lung tissue H-R induced significant increases blood concentrations of inflammatory mediators and tissue mRNA expression of COX related to elevation of HPV responses. COX II inhibitor celecoxib attenuated the HPV responses by reducing TxB(2) release.
Results suggest that targeting depressive symptoms may reduce the economic and personal burden of BED for women.