Does a CCRK-EZH2 epigenetic circuitry drives hepatocarcinogenesis and associate with tumor recurrence and poor survival of patients?
These findings uncover an epigenetic vicious cycle in hepatocarcinogenesis that operates through reciprocal regulation of CCRK and EZH2, providing novel therapeutic strategy for HCC.
The findings confirm the high risk of falling in PD patients. Also these results have implications for developing fall prevention programs for PD patients.