Does german cockroach extract activate protease-activated receptor 2 in human airway epithelial cells?
These results indicate that GCE has a direct effect on human airway epithelial cells, in particular generating [Ca(2+)](i) oscillations through Ca(2+) release from thapsigargin-sensitive Ca(2+) stores through activation of PAR-2.
Small sample size provides limited power to detect differences in response.