Does [ DNA polymerase delta-interacting protein 1 enhance GFP protein degradation ]?
Over-expression of PDIP1 can promote the degradation of exogenous GFP, and the degradation might be caused via proteasome pathway. Our results suggest that PDIP1 might have a hand in the degradation of some proteins in cells.
These data provide a mechanism for enhancement of platelet activity by alpha(IIb)beta(3) inhibitors, but also reveal a potentially important signaling pathway operating from the integrin to GPVI signaling.