Are chromosome Y variants from different inbred mouse strains linked to differences in the morphologic and molecular responses of cardiac cells to postpubertal testosterone?
Although post-pubertal testosterone increased the size of cardiomyocytes from male C56BL/6J mice but not that from their C57BL/6J-chrYA counterparts, it affected gene expression in the hearts from both strains. However, several cardiac genes responded to post-pubertal testosterone in a strict strain-selective manner, which provides possible mechanisms explaining how chrY may, in part via interference with androgen regulatory events, be linked to morphologic differences of cardiac cells of adult male mice.
The hypothesis that peritonectomy produces greater CO2 absorption during CO2 pneumoperitoneum was disproved under these experimental conditions.