Are myofibroblasts responsible for collagen synthesis in the stroma of human hepatocellular carcinoma : an in vivo and in vitro study?
Myofibroblasts are the main source of collagens in the stroma of hepatocellular carcinoma. Our data also indicate that tumoral hepatocytes increase extracellular matrix deposition by cultured myofibroblasts, probably by post-transcriptional mechanisms. The generation of hepatocellular carcinoma stroma by myofibroblasts could thus be under control of tumoral cells.
There was no relationship between the value of the resistance index and the cavernous wall resistance, except in patients capable of developing a full erection after vasodilator injection.