Does tWIST1 regulate the activity of ubiquitin proteasome system via the miR-199/214 cluster in human end-stage dilated cardiomyopathy?
The TWIST1/miR-199/214 axis is down-regulated in dilated cardiomyopathy, which is likely to play a role in the increased activity of the UPS. This may contribute to the loss of cardiac mass during dilatation of the heart.
Light-activated sealing of cross-linked human amnion results in superior outcomes when compared with conventional suture.