Is tibiofemoral subchondral surface ratio ( SSR ) a predictor of osteoarthritis symptoms and radiographic progression : data from the Osteoarthritis Initiative ( OAI )?
A larger medial SSR is protective against developing OA-related symptoms. A larger lateral SSR is protective against lateral OA incidence or progression. Finally, lateral and medial SSR are stable over time and are highly reproducible across MRI studies.
The present results suggest a functional effect of hippocampal PLA(2) on the neurochemistry of memory acquisition and support the hypothesis that reduced PLA(2) activity may contribute to memory impairment in Alzheimer's disease.