Does hyperinsulinemia inhibit myocardial protein degradation in patients with cardiovascular disease and insulin resistance?
Acute hyperinsulinemia markedly suppresses myocardial protein degradation in patients with cardiovascular disease who are resistant to its effects on whole-body glucose metabolism. This antiproteolytic action represents a potential mechanism by which hyperinsulinemia could contribute to the development of myocardial hypertrophy in patients with cardiovascular disease.
Telomere maintenance represents a viable target for anticancer agents.