Do curcumin-altered p53-response genes regulate radiosensitivity in p53-mutant Ewing 's sarcoma cells?
These results suggest that curcumin potentially radiosensitizes p53-mutant ES cells by regulating IR-modulated p53-response genes. However, the curcumin-associated p53-independent regulation of downstream targets remains to be explored.
A replication study using larger samples may be required for conclusive results.