Is circulating surfactant protein A ( SP-A ) , a marker of lung injury , associated with insulin resistance?
Lung-derived SP-A protein was associated with altered glucose tolerance and insulin resistance in 164 nonsmoking men.
These findings suggest that in these patients, coronary spasm may have been induced by arterial hyperreactivity because of local inflammation in the coronary arterial wall and that the corticosteroids suppressed the arterial hyperreactivity by alleviating the inflammation. Corticosteroids may be considered as a treatment choice for patients with refractory vasospastic angina, particularly when the patient has an allergic tendency, such as bronchial asthma.