Are severe coronary artery calcifications associated with ischemia in patients undergoing medical therapy?
The presence of a CAC score greater than 400 is associated with ischemia in a population receiving good medical therapy. The detection of significant CAC in these individuals warrants additional evaluation for ischemia.
These data emphasize that an irradiation-induced, transient up-regulation of HLA-E on macrovascular ECs might confer protection against NK cell-mediated vascular injury.