Is phosphoinositide 3-kinase/Akt pathway involved in mediating the anti-inflammation effects of magnesium sulfate?
Enhancing PI3K/Akt activity is a crucial mechanism underlying the anti-inflammation effects of MgSO4.
HR response during MS is increased in patients with SLVD, whereas blood pressure responses are similar to those in patients with preserved LV function. Hemodynamic reactivity is unrelated to MS-induced ischemia.