Is posterior sagittal anorectoplasty superior to sacroperineal-sacroabdominoperineal pull-through : a long-term follow-up study in boys with high anorectal anomalies?
In boys with high anorectal anomalies, PSARP clearly is superior to sacroperineal and sacroabdominoperineal pull-through in terms of long-term bowel function and faecal continence.
Our work provides fresh insights into liver development, suggesting that microbial-derived cues may drive the maturation of CYP450 enzymes postpartum. Addition of these cues results in the first functional, inducible, hPSC-derived hepatocyte for predictive toxicology.