Does bornyl caffeate induce apoptosis in human breast cancer MCF-7 cells via the ROS- and JNK-mediated pathways?
The present study demonstrated that bornyl caffeate induced apoptosis in the cancer cell line MCF-7 via activating the ROS- and JNK-mediated pathways. Thus, bornyl caffeate may be a potential anticancer lead compound.
The high prevalence o tuboperitoneal factor and additional pelvic pathology in these infertile women reveal the importance of laparoscopic evaluation. We recommend the use of laparoscopy and dye test as a first line investigation in our environment to detect these conditions early enough when treatment modalities like assisted reproduction will still be beneficial.