Does knee extensor isometric unsteadiness predict functional limitation in older adults?
This study suggests that knee extensor isometric steadiness performance does not carry over to tasks of everyday living, and older subjects, regardless of age, have similar steadiness values. Because the strength-to-weight ratio predicted the most variance in functional performance, it is recommended that muscle strength be improved to increase function in older adults.
These findings demonstrate for the first time the involvement of the TGFβ1/ERK/NF-κB signaling pathway in ES-activated fibroblasts. The ES induced phenotype switch proves stable in subculture and in animal, pointing potential application in wound healing.