Does the exometabolome of Clostridium thermocellum reveal overflow metabolism at high cellulose loading?
C. thermocellum is able to utilize industrially relevant concentrations of cellulose, up to 93 g/L. We report here one of the highest degrees of crystalline cellulose utilization observed thus far for a pure culture of C. thermocellum, the highest maximum substrate utilization rate and the highest amount of isobutanol produced by a wild-type organism.
Young patients with colorectal cancer had clinical and pathological presentation similar to that of older patients.