Does intervention to increase physical activity in irritable bowel syndrome show long-term positive effects?
An intervention to increase physical activity has positive long-term effects on IBS symptoms and psychological symptoms.
Since cell activity is dependent on the cell morphology and extracellular matrix composition, these findings indicate that in human normal palate fibroblasts diphenylhydantoin can modify cytoskeletal components and extracellular matrix-cell adhesion, with consequent effects on gene expression. These changes might be related to anomalous palate development.