Is premature ovarian failure in nobox-deficient mice caused by defects in somatic cell invasion and germ cell cyst breakdown?
These results indicate that POF syndrome in Nobox deficient mice results from the faulty signaling between somatic and germ line components during embryonic development. In addition, the extremely unusual and abnormal presence of adherens junctions between unseparated oocytes within syncytial follicles indicates that faulty communication between somatic and germ cells is involved in, or leads to, abnormalities in the cell adhesion program.
des-γ-carboxyl prothrombin production is associated with tumor angiogenesis in HCC.