Does hIV-1 subtype variability in Vif derived from molecular clones affect APOBEC3G-mediated host restriction?
In the absence of A3G, Vif subtype origin did not impact viral replication. In the presence of A3G the subtype origin of Vif had a differential effect on viral replication. Vif derived from a subtype C molecular clone was less effective at overcoming A3G-mediated inhibition than Vif derived from either subtype B or CRF02_AG molecular clones.
Non-invasive CFR is an independent predictor of LVR after successful primary angioplasty of anterior STEMI.