Does reduction of Intracellular Chloride Concentration promote Foam Cell Formation?
This data provide strong evidence that reduction of [Cl(-)]iis a critical contributor to intracellular lipid accumulation, suggesting that modulation of [Cl(-)]iis a novel avenue to prevent foam cell formation and atherosclerosis.
There have been several attempts to define CRS in the past, but an all including definition or classification system for this disorder does not currently exist. Fever is a factor under discussion. We found no significant difference between the preoperative body temperature in CRS patients and controls. These results suggest that fever is not a relevant symptom in CRS.