Do genetic polymorphisms of cytochrome P450 enzymes influence metabolism of the antidepressant escitalopram and treatment response?
Our results suggest that the genetic polymorphisms in CYP2C19 may be influencing S-CIT serum concentrations, and that specific CYP2D6 polymorphisms may be predicting patient treatment outcomes based on gene dosage analyses.
Our results indicate that the increase in BP during leg crossing cannot be explained by wave reflection. We found no change in the augmentation index during leg crossing at the knee level. Central BP and peripheral BP are equally influenced by leg crossing.