Does postoperative radiation therapy after complete resection of thymoma have little impact on survival?
The authors concluded that surgical resection alone is sufficient for thymoma patients with Masaoka stage I and II, and those with WHO cell types A, AB, and B1. Furthermore, an optimal treatment strategy should be established for patients with Masaoka stage III/IV and WHO cell type B2/B3 thymomas.
These preliminary findings indicate that objective responses in Phase I trials may have predictive value for later regulatory approval.