Does amphiregulin promote the maturation of oocytes isolated from the small antral follicles of the rhesus macaque?
These data indicate that AREG levels increase in rhesus macaque pre-ovulatory follicles after an ovulatory stimulus, and a specific concentration of AREG (10 ng/ml) enhances rhesus macaque oocyte nuclear maturation but not cytoplasmic maturation from SAFs obtained during the natural menstrual cycle. However, owing to the small number of samples in some treatment groups, further studies are now required.
HFDs induce insulin resistance, and this can be reversed by MFN2 over-expression targeting the insulin signaling pathway.