Are hypertriglyceridemia and low high-density lipoprotein cholesterolemia associated with increased hazard for urolithiasis?
Our study implies that dyslipidemia may play a crucial part in urinary stone risk.
Our data identifies Tbx4 as a novel transcriptional activator of Shox2 during murine fore- and hindlimb development. Tbx4 is also regulated by Shox2 specifically in the forelimb bud possibly via a feedback mechanism. These data extend our understanding of the role and regulation of Tbx4 and Shox2 in limb development and limb associated diseases.