Does murine IL-2 secreting recombinant Bacillus Calmette-Guerin augment macrophage-mediated cytotoxicity against murine bladder cancer MBT-2?
rBCG secreting IL-2 showed significant antitumor activity and cytokine production and this will be a promising agent for bladder cancer patient to reduce both clinical dose and side effects of BCG for immunotherapy.
Our study revealed no correlation of disease activity and serum leptin levels. Therefore leptin does not seem to be an appropriate biomarker to monitorize inflammation in RA.