Are polymorphisms of the human platelet antigens HPA-1 , HPA-2 , HPA-3 , and HPA-5 on the platelet receptors for fibrinogen ( GPIIb/IIIa ) , von Willebrand factor ( GPIb/IX ) , and collagen ( GPIa/IIa ) correlated with an increased risk for stroke?
Our results indicate that the HPA-1, HPA-2, HPA-3, and HPA-5 polymorphisms are not associated with an increased risk for stroke.
We established a human herniation model that reliably produced nucleus extrusion during cyclic loading by selecting specimens with low disc degeneration. The Barricaid seems to prevent nucleus from reherniating. The reliability of this method suggests the opportunity to investigate other anulus closure devices and nucleus replacement techniques critically.