Mother lode (disambiguation)
A mother lode is a principal vein or zone of veins of gold or silver ore.
Mother lode or motherlode may also refer to:

Music
Motherlode (band), a Canadian pop rock group formed in 1969
Mother Lode (album), 1974, by Loggins and Messina
Motherlode (James Brown album), 1988
Motherlode (Sara Hickman album), 2006
"Motherlode", a song by Howe II on their 1991 album Now Hear This
"The Mother Lode", a song from Thom Yorke's 2014 album Tomorrow's Modern Boxes

Other uses
The California Mother Lode, the main gold deposits of the California Gold Rush
Mother Lode (film), a 1982 adventure film directed by and starring Charlton Heston
"The Mother Lode", an episode of the TV series Prison Break
Mother Lode (Methow Mountains), a mountain summit located in the North Cascades, in Okanogan County, Washington
The Motherlode, a climbing area in the Pendergrass-Murray Recreational Preserve of Red River Gorge, Kentucky

See also
"The Motherload", a 2014 song by Mastodon
Super Motherload, a 2013 video game developed by XGen Studios