SPM
SPM may refer to:

Places
Saint Pierre and Miquelon (ISO 3166-1 code), an overseas French territory
Salón de la Plástica Mexicana, an art museum in Mexico City
Salsali Private Museum, Dubai, UAE
Shyama Prasad Mukherji College, University of Delhi, India
St Philip's Marsh depot, Bristol, UK, rail depot code

Organizations
Socialist Party of Canada (Manitoba)
Socialist Party of Macedonia
Somali Patriotic Movement
Sociedade Portuguesa de Matemática, the Portuguese Mathematical Society

Science and computing
Scanning probe microscopy
Scratchpad memory, in computing
Self-phase modulation, nonlinear light-matter interaction
Specialized proresolving mediators, cell signaling molecules
Standard Progressive Matrices (IQ test)
Suspended particulate matter

Software
Statistical parametric mapping of brain activity

Business and industry
Supplier performance management
Single-point mooring, for tankers

People
South Park Mexican, aka SPM, American rapper
S. P. Muthuraman, Indian film director
Sean Patrick Maloney, American politician.

Other
Akukem language (ISO 639:spm), a Ramu language of Papua New Guinea
IPCC Summary for Policymakers
Sijil Pelajaran Malaysia (Malaysian Certificate of Education)
Super Paper Mario, a video game for the Nintendo Wii