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  Victor Frankenstein (Leonard Whiting) is a man training as a doctor, engaged to Elizabeth Fanshawe (Nicola Pagett). After Victor's younger brother, William, drowns, Victor renounces his belief in God and declares that he would join forces with the Devil if he could learn how to restore his brother to life.
  Shortly afterward, Victor leaves for London to train in anatomy. He immediately meets a scientist named Henry Clerval (David McCallum), who Victor later learns has discovered how to preserve dead matter and restore it to life. As Victor becomes fascinated by Clerval's experiments, Clerval reveals his ultimate plan: to create a new race of invincible, physically perfect beings by using solar energy to animate "the Second Adam" constructed from parts of corpses. Clerval is unable to complete it on his own due to a worsening heart condition. Frankenstein volunteers to help and the lab is completed.
  Word reaches the pair that several peasant lads have been killed in a mine collapse. After their burial the doctors quickly dig up the bodies and stitch together a physically perfect human. The night before the creation, Clerval discovers in a most disturbing way that a reanimated arm set aside weeks earlier has become diseased, unsightly and deformed. Shocked and overcome, Clerval suffers a heart attack and, unable to get his medication in time, dies in the middle of recording his horrible discovery in the journal.
  The next morning, Victor finds Clerval's body and misreads the incomplete journal entry ("The process is r--") as meaning "the process is ready to begin" rather than the intended meaning of "the process is reversing itself". Since neither of them wanted the perfect body to have the brain of a peasant, Victor transplants Clerval's brain into their creation and he is able to complete the experiment. Victor introduces his creation into high-class London society, passing him off as a friend from a far-off country with little grasp of English.
  Victor's sweet and guileless creation wins the admiration of London's elite class. Shortly thereafter, Victor discovers the still-living but now repulsive arm in Clerval's cupboard and realizes that a flaw in the system has caused the reanimation process to reverse itself. He destroys the deformed arm, but soon finds that the same reversal process is beginning to break down the Creature's tissues.
  Victor desperately searches for a way to correct the problem, but is unsuccessful. The Creature (Michael Sarrazin), unaware of his degenerating appearance, does not understand Victor's increasing coldness towards him. After Victor's landlady, Mrs. Blair (Agnes Moorehead), dies from shock after seeing the Creature, Victor is forced to take him back to the laboratory. He contemplates destroying the sleeping Creature but cannot bring himself to do it.
  At the laboratory, the Creature becomes distraught after discovering his deformed appearance. He attempts to commit suicide by stabbing himself in the chest with a shard of broken glass, but is unharmed. He flees the laboratory and jumps into the sea from the White Cliffs of Dover. Victor assumes the Creature is dead and realizes that perhaps it is for the best.
  The Creature has washed up on the beach, alive and unharmed. He wanders into the countryside, where he befriends an elderly blind peasant (Ralph Richardson). The blind man is eager to introduce his new friend to his granddaughter Agatha (Jane Seymour) and her boyfriend Felix (Dallas Adams), but the Creature resists. He observes the family from afar and falls in love with Agatha. When Agatha and Felix return home unexpectedly the following day, they encounter the Creature and react in horror. Felix is killed and Agatha, fleeing in terror, is struck by a carriage and is also killed.
  The Creature takes Agatha's body back to the laboratory, intent on asking his creator to restore her to life. He arrives to find that Victor has long since left and that the laboratory is now occupied by Dr. Polidori (James Mason), the crippled former mentor of Clerval. Polidori is aware of the Creature's origins and agrees to help. In the meantime, Victor has abandoned his experiments and is celebrating his marriage to Elizabeth. He is confronted by Polidori, who blackmails him into returning to the laboratory to assist him in creating a female being.
  Polidori reveals that it was he who perfected the preservation and reanimation of dead flesh, only to have his secrets stolen by Clerval. He rejects Clerval's use of solar power in favor of his own chemical reanimation process. Victor attaches Agatha's head to a new body and they bring to life a beautiful creature whom Polidori names Prima. Victor, believing that his association with Polidori and the Creature is over, leaves for his honeymoon with Elizabeth.
  While Victor and Elizabeth are away, Polidori returns and persuades Elizabeth's family to take Prima in as a houseguest; when the couple return, Victor is forced to accept the situation. It becomes evident that Prima is evil, and Elizabeth begs Victor to send her away. At the laboratory, Victor confronts Polidori, who agrees to take Prima away. Before they leave the laboratory, Polidori attempts to kill the Creature by pushing him into a vat of acid, but Victor stops him. Polidori traps the Creature in the laboratory and sets the building on fire.
  A few weeks later, a lavish ball is held at the Fanshawe mansion to present Prima to society. Prima delights the guests, and a beaming Polidori reveals his ultimate plan to use her as a courtesan to gain international political influence. Suddenly, the badly burned Creature bursts into the ballroom and confronts Prima, who in a hissing fury attacks him. He rips off her neckband, revealing the scar where her head was attached to her body. In the chaos that follows, the Creature rips her head off and drops it at Polidori's feet. To avoid scandal and an impending police investigation, Victor and Elizabeth decide to leave England and travel to America to begin a new life.
  After setting sail, Victor and Elizabeth are dismayed to discover that Polidori is also on board the ship. Elizabeth sees the Creature hiding in Polidori's cabin and locks the two men in the room together. Because of Polidori's previous use of hypnosis, Clerval's mind has resurfaced in the Creature, and he is determined to have his revenge on Polidori. Victor unlocks the door and the conflict moves to the deck, where the Creature strings Polidori to the top of a mast during a storm, where he is struck by lightning and and electrocuted, and Victor is knocked unconscious and falls to the deck. The crew flees in a lifeboat and the Creature takes Victor below deck to care for him.
  The Creature lashes the wheel of the ship on a heading straight for the North Pole. In Victor's cabin, Elizabeth cruelly taunts the Creature, who (his mind now that of Clerval) strangles her. When Victor awakens, he finds the frozen body of Elizabeth on deck and the ship locked in ice. He follows the Creature to an ice cave, where he confesses that the entire tragedy was caused by his rejection of the helpless, deteriorating Creature. He also knows that, upon his death, the Creature will be utterly alone, cursed with an "iron body" that will keep him alive against his will. Victor begs the Creature's forgiveness; the sound of his shouts sets off an ice avalanche. As tons of ice begin to fall upon them both, the Creature (in Clerval's voice) forgives his creator.
question: Who has Victor's lab been taken over by?
answer: Dr. Polidori