The Schick Test indicates susceptibility or immunity to which disease?
Schick test result. This swelling disappears after a few days. If the person has an immunity, then little or no swelling and redness will occur, indicating a negative result. Results can be interpreted as: The test was created when immunizing agents were scarce and not very safe, however as newer and safer toxoids were made available there was no more requirement for susceptibility tests. Schick test The Schick test, invented between 1910 and 1911, is a test used to determine whether or not a person is susceptible to diphtheria. It was named after its inventor, Béla Schick (1877–1967), a Hungarian-born American pediatrician.
Mendelian susceptibility to mycobacterial disease discovery of MSMD in 1996, multiple autosomal and two X-linked genes are identified in MSMD phenotypes, classified under the category of defects in intrinsic and innate immunity in the 2017 IUIS Phenotypic Classification for Primary Immunodeficiencies. Mendelian susceptibility to mycobacterial disease Mendelian susceptibility to mycobacterial disease (MSMD) is a rare genetic disease. It is a primary immunodeficiency featured by molecular defects in IL12/IFNγ dependent signalling pathway, leading to increased susceptibility to local or disseminated infections by environmental mycobacteria, "Mycobacterium bovis" Bacille Calmette-Guerin strain, nontyphoidal and typhoidal "Salmonella" serotypes. Phagocytes are important components of the innate immune system for the body