Berkeley Hundred and 17 days before the Pilgrims arrived aboard the "Mayflower" at Plymouth, Massachusetts to establish their Thanksgiving Day in 1621. On March 22, 1622, Opchanacanough, head of the Powhatan Confederacy, began the Second Anglo-Powhatan War with a coordinated series of attacks against English settlements along the James River, known in English histories as the Indian massacre of 1622. Nine colonists were killed at Berkeley. The assault took a heavier toll elsewhere, killing about a third of all the colonists, and virtually wiping out Wolstenholme Towne on Martin's Hundred and Sir Thomas Dale's progressive development and new college at Henricus. Jamestown
Pilgrims (Plymouth Colony) how weakened the settlement had actually become. Between the landing and March, only 47 colonists had survived the diseases that they contracted on the ship. During the worst of the sickness, only six or seven of the group were able to feed and care for the rest. In this time, half the "Mayflower" crew also died. William Bradford became governor in 1621 upon the death of John Carver. On March 22, 1621, the Pilgrims of Plymouth Colony signed a peace treaty with Massasoit of the Wampanoags. The patent of Plymouth Colony was surrendered by Bradford to the freemen in 1640,