Vogt–Koyanagi–Harada disease Vogt–Koyanagi–Harada disease Vogt–Koyanagi–Harada disease (VKH), also known as Vogt–Koyanagi–Harada syndrome, uveomeningitis syndrome and uveomeningoencephalitic syndrome, is a multisystem disease of presumed autoimmune cause, that affects pigmented tissues, which have melanin. The most significant manifestation is bilateral, diffuse uveitis, which affects the eye. VKH may variably also involve the inner ear with effects on hearing, the skin, and the meninges of the central nervous system. The disease is characterised by bilateral diffuse uveitis, with pain, redness and blurring of vision. The eye symptoms may be accompanied by a varying constellation of systemic symptoms, such as auditory (tinnitus, vertigo, and hypoacusis), neurological
Supernumerary body part two or more different populations of genetically distinct cells that originated in different zygotes that have merged; anatomical structures are typically mixed depending on which cells are prevalent in different body parts, for example plants can have two different types of flowers. A mosaic is a genetic anomaly similar in nature and effects to a chimera: genetically different populations of cells within one organism, originated from some propagated mutation of a single cell rather than from outside sources. In Hindu mythology, additional limbs and heads are considered a sign of power. In Greek mythology, Artemis, the goddess of fertility, was