Modern art his career and in the development of modern painting. It reflected Matisse's incipient fascination with primitive art: the intense warm color of the figures against the cool blue-green background and the rhythmical succession of the dancing nudes convey the feelings of emotional liberation and hedonism. Initially influenced by Toulouse-Lautrec, Gauguin and other late-19th-century innovators, Pablo Picasso made his first cubist paintings based on Cézanne's idea that all depiction of nature can be reduced to three solids: cube, sphere and cone. With the painting "Les Demoiselles d'Avignon" (1907), Picasso dramatically created a new and radical picture depicting a raw and primitive
Alternative explanations of the "grandmother" cell a study performed by Logothetis and Pauls, this is seen with the spiking of a single macaque monkey neuron when presented with a paper clip bent in a certain way at a variety of angles. At a specific angle, the neuron fires rapidly. At different angles or shapes, it does not. A grandmother cell, by contrast, would seem to fire at many different shapes and angles. And it is very difficult to imagine what kind of mechanism "will bind ... information from disparate sensory sources" in a cell, which makes a grandmother cell "a tremendous connectivity puzzle". In 2001, Kreiman