Vogt–Koyanagi–Harada disease Vogt–Koyanagi–Harada disease Vogt–Koyanagi–Harada disease (VKH), also known as Vogt–Koyanagi–Harada syndrome, uveomeningitis syndrome and uveomeningoencephalitic syndrome, is a multisystem disease of presumed autoimmune cause, that affects pigmented tissues, which have melanin. The most significant manifestation is bilateral, diffuse uveitis, which affects the eye. VKH may variably also involve the inner ear with effects on hearing, the skin, and the meninges of the central nervous system. The disease is characterised by bilateral diffuse uveitis, with pain, redness and blurring of vision. The eye symptoms may be accompanied by a varying constellation of systemic symptoms, such as auditory (tinnitus, vertigo, and hypoacusis), neurological
Tinnitus masker the sound is tuned to the pitch, loudness and other qualities of the tinnitus. However, frequencies widely divergent from the tinnitus frequency may also mask the tinnitus, if they are of sufficient loudness. The minimum energy (or loudness) mask is usually one closely matched to the central frequency and bandwidth of the tinnitus. But it has also been discovered that a tinnitus mask close to the frequency of the tinnitus can be ineffective, while a masker with a different frequency or bandwidth effectively masks the tinnitus. This indicates different origins of tinnitus. Tinnitus maskers may use music or natural sounds,