Southwest Florida Southwest Florida Southwest Florida is the region along the southwest Gulf coast of the U.S. state of Florida. The area is known for its sugar white sand beaches, lush tropical landscape, and winter resort economy. Definitions of the region vary, though its boundaries are generally considered to put it south of the Tampa Bay area, west of Lake Okeechobee, and mostly north of the Everglades and to include Manatee, Sarasota, Charlotte, Lee, and Collier counties. For some purposes, the inland counties of DeSoto, Glades, and Hendry, and the thinly populated mainland section of Monroe County, south of Collier, are also
Miami River (Florida) to improve the river's condition. Although it is widely believed that the name is derived from a Native American word that means "sweet water", the earliest mention of the name comes from Hernando de Escalante Fontaneda, a captive of Indians in southern Florida for 17 years, when he referred to what is now Lake Okeechobee as the "Lake of Mayaimi, which is called Mayaimi because it is very large". The Mayaimi Indians were named after the lake, beside which they lived. Spanish records include the cacique of "Maimi" in a group of 280 Florida Indians that arrived in Cuba in