Heart Motu Cordis" (1628) by the English physician William Harvey. Harvey's book completely describes the systemic circulation and the mechanical force of the heart, leading to an overhaul of the Galenic doctrines. Otto Frank (1865–1944) was a German physiologist; among his many published works are detailed studies of this important heart relationship. Ernest Starling (1866–1927) was an important English physiologist who also studied the heart. Although they worked largely independently, their combined efforts and similar conclusions have been recognized in the name "Frank–Starling mechanism". Although Purkinje fibers and the bundle of His were discovered as early as the 19th century, their
And to Think That I Saw It on Mulberry Street heart on sight", and "as original in conception, as spontaneous in the rendering as it is true to the imagination of a small boy." Moore sent a copy of the book to English children's author Beatrix Potter, who wrote back, "What an amusing picture book ... I think it the cleverest book I have met with for many years. The swing and merriment of the pictures and the natural truthful simplicity of the untruthfulness ... Too many story books for children are condescending, self-conscious inventions—and then some trivial oversight, some small incorrect detail gives the whole show away. Dr. Seuss