Catherine Carey Francis and Lady Knollys produced a number of offspring who survived to maturity. Of the children listed, only the last, Dudley, is known to have died in infancy: The possibility that Catherine, and perhaps her brother Henry, were illegitimate children of Henry VIII, appears in many works of fiction, including Philippa Gregory's "The Other Boleyn Girl". Catherine Carey is also a character in Gregory's "The Boleyn Inheritance", where she is sent to the royal court during the time of Queens Anne of Cleves and Catherine Howard, and in "The Virgin's Lover", where, as the mother of the seventeen-year-old Lettice Knollys,
Catherine Carey, Countess of Nottingham at Hatfield House as a child during the reign of Elizabeth's elder sister Mary. On Elizabeth's accession, Catherine and her younger sister Philadelphia came to court as maids of honour under the auspices of their aunt, Catherine Carey, the queen's first cousin and a Lady of the Bedchamber. In July 1563, Catherine married Charles Howard (1536–1624), later 2nd Baron Howard of Effingham, Lord High Admiral of England, and first Earl of Nottingham (1597). Catherine was appointed First Lady of the Bedchamber by 1572. Her daughter Elizabeth, the queen's goddaughter, was a maid of honour from 1576 until 1583, the year