Knee Knee In humans and other primates, the knee joins the thigh with the leg and consists of two joints: one between the femur and tibia (tibiofemoral joint), and one between the femur and patella (patellofemoral joint). It is the largest joint in the human body. The knee is a modified hinge joint, which permits flexion and extension as well as slight internal and external rotation. The knee is vulnerable to injury and to the development of osteoarthritis. It is often termed a "compound joint" having tibiofemoral and patellofemoral components. (The fibular collateral ligament is often considered with tibiofemoral components.) The
Femur the bone. Some species of whales, snakes, and other non-walking vertebrates have vestigial femurs. One of the earliest known vertebrates to have a femur is the "eusthenopteron", a prehistoric lobe-finned fish from the Late Devonian period. Structures analogous to the third trochanter are present in mammals, including some primates. In invertebrate zoology the name "femur" appears in arthropodology. The usage is not homologous with that of vertebrate anatomy; the term "femur" simply has been adopted by analogy and refers, where applicable, to the most proximal of (usually) the two longest jointed segments of the legs of the arthropoda. The two