Berkeley Hundred and 17 days before the Pilgrims arrived aboard the "Mayflower" at Plymouth, Massachusetts to establish their Thanksgiving Day in 1621. On March 22, 1622, Opchanacanough, head of the Powhatan Confederacy, began the Second Anglo-Powhatan War with a coordinated series of attacks against English settlements along the James River, known in English histories as the Indian massacre of 1622. Nine colonists were killed at Berkeley. The assault took a heavier toll elsewhere, killing about a third of all the colonists, and virtually wiping out Wolstenholme Towne on Martin's Hundred and Sir Thomas Dale's progressive development and new college at Henricus. Jamestown
Maritime history of Florida Johns River for future settlement and then headed north to establish Charlesfort in present-day Parris Island, South Carolina. The colony failed, and in 1564, René Goulaine de Laudonnière led the settlers back to Florida and established Fort Caroline in what is now Jacksonville. In 1565, Spaniard Pedro Menéndez de Avilés captured Fort Caroline in a brutal fight with the French and established St. Augustine, the first permanent European colony in the continental United States. In 1568, Frenchman Dominique de Gourgues recaptured Fort Caroline. In 1569, the Spanish built a watchtower at Matanzas Inlet to watch the horizon and warn St.