Thanksgiving (United States) as early as 1607, with the first permanent settlement of Jamestown, Virginia holding a thanksgiving in 1610. In 1619, 38 English settlers arrived at Berkeley Hundred in Charles City County, Virginia. The group's London Company charter specifically required "that the day of our ships arrival at the place assigned... in the land of Virginia shall be yearly and perpetually kept holy as a day of thanksgiving to Almighty God." Three years later, after the Indian massacre of 1622, the Berkeley Hundred site and other outlying locations were abandoned and colonists moved their celebration to Jamestown and other more secure spots.
History of Massachusetts of the Indian population before the first large-scale arrival of settlers in the 1630s. Large numbers of natives were decimated by virgin soil epidemics such as smallpox, measles, influenza, and perhaps leptospirosis, against which they had no immunity. In 1617–1619, smallpox killed 90% of the Native Americans in the region. The first English settlers in Massachusetts, the Pilgrims, established their settlement at Plymouth in 1620, and developed friendly relations with the native Wampanoag. This was the second successful permanent English colony in North America, after the Jamestown Colony. Before heading to the New World, they migrated to Holland to escape