Holby City cast as Greg Douglas in series twelve. "Holby City" and "Casualty" are both set in Holby City Hospital, in the fictional county of Wyvern, in the southwest of England close to the Welsh border. The city exterior is represented by Bristol, though "Holby City" is filmed at BBC Elstree Centre in Borehamwood, Hertfordshire. The "Casualty" set in Bristol was not large enough to encompass the surgical ward and operating theatre required for "Holby City", and as a result, some crossover scenes in the first episode had to be shot twice, first on the "Casualty" set and then again at Elstree,
Characters of Holby City the characters gathered together in the hospital bar at the end of the episode, and raised a toast "To the one and only Sandy!" Estelle "Essie" Harrison, played by Kaye Wragg, made her first appearance in the sixteenth series episode "My Name Is Joe", which aired on 6 May 2014. Essie is a Staff Nurse at Holby City Hospital. She came to the hospital with her dying grandfather and she started a relationship with Sacha Levy (Bob Barrett). She later moved to Germany after her grandfather died. In October 2014, it was announced that Wragg would be returning to "Holby