Heart Motu Cordis" (1628) by the English physician William Harvey. Harvey's book completely describes the systemic circulation and the mechanical force of the heart, leading to an overhaul of the Galenic doctrines. Otto Frank (1865–1944) was a German physiologist; among his many published works are detailed studies of this important heart relationship. Ernest Starling (1866–1927) was an important English physiologist who also studied the heart. Although they worked largely independently, their combined efforts and similar conclusions have been recognized in the name "Frank–Starling mechanism". Although Purkinje fibers and the bundle of His were discovered as early as the 19th century, their
Defence of the True and Catholic Doctrine of the Sacrament of the Body and Blood of Christ Defence of the True and Catholic Doctrine of the Sacrament of the Body and Blood of Christ The Defence of the True and Catholic Doctrine of the Sacrament of the Body and Blood of Christ is a book by Thomas Cranmer, Archbishop of Canterbury. It was published in July 1550, and was Cranmer's first full-length book, but at his trial in September 1555, he said that it had been written seven years earlier, in 1548. Although Cranmer is concerned that "very simple and unlearned people" would understand and be edified by his book, the "Defence" is largely a polemic work,