John, King of England Normandy and Anjou until 1259, but John's continental losses and the consequent growth of Capetian power in the 13th century proved to mark a "turning point in European history". John's first wife, Isabel, Countess of Gloucester, was released from imprisonment in 1214; she remarried twice, and died in 1217. John's second wife, Isabella of Angoulême, left England for Angoulême soon after the king's death; she became a powerful regional leader, but largely abandoned the children she had had by John. John had five legitimate children, all by Isabella. His eldest son, Henry III, ruled as King of England for the
Isabella of Aragon, Queen of Portugal Manuel later married Isabella's younger sister, Maria of Aragon, who bore him his son and heir, John III. Portugal and Spain were finally united between 1580 and 1640, after Philip II of Spain, Isabella's great-nephew via her sisters, Maria and Joanna, successfully claimed the throne of Portugal as a son of Isabella of Portugal, the daughter of Maria and Manuel. Isabella of Aragon, Queen of Portugal Isabella, Princess of Asturias (2 October 1470 – 23 August 1498) was a Queen consort of Portugal and heir presumptive of King Ferdinand II of Aragon and Queen Isabella I of Castile, as their