Heart Motu Cordis" (1628) by the English physician William Harvey. Harvey's book completely describes the systemic circulation and the mechanical force of the heart, leading to an overhaul of the Galenic doctrines. Otto Frank (1865–1944) was a German physiologist; among his many published works are detailed studies of this important heart relationship. Ernest Starling (1866–1927) was an important English physiologist who also studied the heart. Although they worked largely independently, their combined efforts and similar conclusions have been recognized in the name "Frank–Starling mechanism". Although Purkinje fibers and the bundle of His were discovered as early as the 19th century, their
Pinky and the Brain (voiced by Maurice LaMarche). In "What Ever Happened to Baby Brain", Brain actually crosses paths, who is working as a busboy in a hollywood restaurant, they find themselves inadvertently yelling in unison, "Things will be different when I take over the world!" In "Project B.R.A.I.N." Brain's name is the backronym for the eponymous project: "Biological Recombinant Algorithmic Intelligence Nexus". His tail is angular and bent —he often uses it to pick the lock of the cage—and his head is large and wide, housing his abnormally large brain. He is highly intelligent and develops complex plans for global domination using politics,