Heart Motu Cordis" (1628) by the English physician William Harvey. Harvey's book completely describes the systemic circulation and the mechanical force of the heart, leading to an overhaul of the Galenic doctrines. Otto Frank (1865–1944) was a German physiologist; among his many published works are detailed studies of this important heart relationship. Ernest Starling (1866–1927) was an important English physiologist who also studied the heart. Although they worked largely independently, their combined efforts and similar conclusions have been recognized in the name "Frank–Starling mechanism". Although Purkinje fibers and the bundle of His were discovered as early as the 19th century, their
Pinky and the Brain wore, and not by a number. Three songs resemble the musical skits in "Animaniacs", matching existing music with new lyrics. Pinky sings "Cheese Roll Call" to John Philip Sousa's march "Semper Fidelis" praising his love for all cheeses from around the world. To the music of "Camptown Races", Brain lists the major parts of the human brain, with Pinky jumping in at the chorus to shout "Brainstem! Brainstem!". "A Meticulous Analysis of History" is set to "When I Was a Lad" from Gilbert and Sullivan's "H.M.S. Pinafore", and sung by both Brain and Pinky, with Brain reciting the rise to