Berkeley Hundred and 17 days before the Pilgrims arrived aboard the "Mayflower" at Plymouth, Massachusetts to establish their Thanksgiving Day in 1621. On March 22, 1622, Opchanacanough, head of the Powhatan Confederacy, began the Second Anglo-Powhatan War with a coordinated series of attacks against English settlements along the James River, known in English histories as the Indian massacre of 1622. Nine colonists were killed at Berkeley. The assault took a heavier toll elsewhere, killing about a third of all the colonists, and virtually wiping out Wolstenholme Towne on Martin's Hundred and Sir Thomas Dale's progressive development and new college at Henricus. Jamestown
St. Augustine, Florida was founded on September 8, 1565, by Spanish admiral Pedro Menéndez de Avilés, Florida's first governor. He named the settlement ""San Agustín"", as his ships bearing settlers, troops, and supplies from Spain had first sighted land in Florida eleven days earlier on August 28, the feast day of St. Augustine. The city served as the capital of Spanish Florida for over 200 years. It was designated as the capital of British East Florida when the colony was established in 1763 until it was ceded to Spain in 1783. Spain ceded Florida to the United States in 1819, and St. Augustine