Vogt–Koyanagi–Harada disease Vogt–Koyanagi–Harada disease Vogt–Koyanagi–Harada disease (VKH), also known as Vogt–Koyanagi–Harada syndrome, uveomeningitis syndrome and uveomeningoencephalitic syndrome, is a multisystem disease of presumed autoimmune cause, that affects pigmented tissues, which have melanin. The most significant manifestation is bilateral, diffuse uveitis, which affects the eye. VKH may variably also involve the inner ear with effects on hearing, the skin, and the meninges of the central nervous system. The disease is characterised by bilateral diffuse uveitis, with pain, redness and blurring of vision. The eye symptoms may be accompanied by a varying constellation of systemic symptoms, such as auditory (tinnitus, vertigo, and hypoacusis), neurological
Body part as an object distinguished by how they are carried out. For example, BPO mime gestures are differentiated by the insertion of a body part to help represent the object itself. Conversely, Imaginary object (IO) pantomimes occur when an individual mimes the use of an object as though the object were actually present. Using a similar example to above, an IO pantomime occurs as an individual pretends to brush their teeth by positioning the hand and fingers as though the toothbrush were actually in their hand: they are pretending the object is actually present. BPO, and BPO measures particularly, are notable in that they