Femur the medial, gives attachment to the fibular collateral ligament of the knee-joint. The femur develops from the limb buds as a result of interactions between the ectoderm and the underlying mesoderm, formation occurs roughly around the fourth week of development. By the sixth week of development, the first hyaline cartilage model of the femur is formed by chondrocytes. Endochondral ossification begins by the end of the embryonic period and primary ossification centers are present in all long bones of the limbs, including the femur, by the 12th week of development. The hindlimb development lags behind forelimb development by 1–2 days.
Tibia Clausa rank. A few of the largest theatre organs, and some church organs, may have a separate 32′ Tibia Clausa rank of 12 pipes. In smaller organs, a "Bourdon" or "Stopped Diapason" may be substituted for a Tibia Clausa at 16′ pitch. The Tibia may be voiced on wind pressures from 10″ to 25″. The Tibia is generally used as a chorus stop, with or without tremulant; it is not normally used as a solo stop due to its relatively dull tone. Other variants of the Tibia Clausa include: Tibia Bass, Tibia Flute, Tibia Major, Tibia Plena (open tibia) and Tibia