Italian War of 1542–1546 and six decades of conflict. Italian War of 1542–1546 The Italian War of 1542–46 was a conflict late in the Italian Wars, pitting Francis I of France and Suleiman I of the Ottoman Empire against the Holy Roman Emperor Charles V and Henry VIII of England. The course of the war saw extensive fighting in Italy, France, and the Low Countries, as well as attempted invasions of Spain and England. The conflict was inconclusive and ruinously expensive for the major participants. The war arose from the failure of the Truce of Nice, which ended the Italian War of 1536–38, to
House of Howard three are earldoms, and the latter a barony. Throughout much of English, and later British history, the Howards have played an important role. Claiming descent from Hereward the Wake, the resister of the Norman conquest who has been much celebrated in folklore, John Howard fought to the death at the Battle of Bosworth Field in defence of the cause for the House of York. They regained favour with the new Tudor dynasty after leading a defence of England from Scottish invasion at the Battle of Flodden, and Catherine Howard subsequently became the fifth wife and Queen consort to King Henry