Heart Motu Cordis" (1628) by the English physician William Harvey. Harvey's book completely describes the systemic circulation and the mechanical force of the heart, leading to an overhaul of the Galenic doctrines. Otto Frank (1865–1944) was a German physiologist; among his many published works are detailed studies of this important heart relationship. Ernest Starling (1866–1927) was an important English physiologist who also studied the heart. Although they worked largely independently, their combined efforts and similar conclusions have been recognized in the name "Frank–Starling mechanism". Although Purkinje fibers and the bundle of His were discovered as early as the 19th century, their
Pinky and the Brain the head. A few times in the series Pinky and Brain indeed pondered the same thing, though in one of these Pinky dismissed his idea as being too stupid. Just one time the answer was "Yes I am!", when Pinky's intelligence is elevated to match Brain's. In another episode, it turns out that what Pinky was pondering was that he and Brain never ponder the same thing, which turned out to be part of what Brain was pondering as well. In a short episode ("Pinky's POV") the spectator sees everything Pinky sees (including his imaginations) and hears his thoughts. His