Pablo Picasso Pablo Picasso Pablo Ruiz Picasso (; ; 25 October 1881 – 8 April 1973) was a Spanish painter, sculptor, printmaker, ceramicist, stage designer, poet and playwright who spent most of his adult life in France. Regarded as one of the most influential artists of the 20th century, he is known for co-founding the Cubist movement, the invention of constructed sculpture, the co-invention of collage, and for the wide variety of styles that he helped develop and explore. Among his most famous works are the proto-Cubist "Les Demoiselles d'Avignon" (1907), and "Guernica" (1937), a dramatic portrayal of the bombing of Guernica
Alternative explanations of the "grandmother" cell a study performed by Logothetis and Pauls, this is seen with the spiking of a single macaque monkey neuron when presented with a paper clip bent in a certain way at a variety of angles. At a specific angle, the neuron fires rapidly. At different angles or shapes, it does not. A grandmother cell, by contrast, would seem to fire at many different shapes and angles. And it is very difficult to imagine what kind of mechanism "will bind ... information from disparate sensory sources" in a cell, which makes a grandmother cell "a tremendous connectivity puzzle". In 2001, Kreiman