Italian War of 1542–1546 and six decades of conflict. Italian War of 1542–1546 The Italian War of 1542–46 was a conflict late in the Italian Wars, pitting Francis I of France and Suleiman I of the Ottoman Empire against the Holy Roman Emperor Charles V and Henry VIII of England. The course of the war saw extensive fighting in Italy, France, and the Low Countries, as well as attempted invasions of Spain and England. The conflict was inconclusive and ruinously expensive for the major participants. The war arose from the failure of the Truce of Nice, which ended the Italian War of 1536–38, to
Hans Holbein the Younger money from him. He painted Denny's portrait in 1541 and two years later designed a clock-salt for him. Denny was part of a circle that gained influence in 1542 after the failure of Henry's marriage to Catherine Howard. The king's marriage in July 1543 to the reformist Catherine Parr, whose brother Holbein had painted in 1541, established Denny's party in power. Holbein may have visited his wife and children in late 1540, when his leave-of-absence from Basel expired. None of his work dates from this period, and the Basel authorities paid him six months salary in advance. The state of