2-Ethyl-2-oxazoline oxazolines towards ring-opening by chloride ions during protonation of the imine nitrogen. The direct reaction of propanoyl chloride with 2-chloroethylamine hydrochloride in the presence of triethylamine avoids the formation of water. Propanal reacts with 2-aminoethanol in "t"-butanol to 2-ethyl-2-oxazoline in the presence of the iodinating reagent 1,3-diiodo-5,5-dimethylhydantoin (DIH) and potassium carbonate. 2-Ethyl-2-oxazoline is a readily water-soluble, colorless liquid which is also soluble in a variety of organic solvents and possesses an amine-like smell. Aqueous solutions react alkaline. The compound is stable in alkaline but hydrolyses under acid action. In anhydrous form, 2-ethyl-2-oxazoline is mostly used as a monomer. The cationic
Ethyl methylphenylglycidate prepared by the condensation of acetophenone and the ethyl ester of monochloroacetic acid in the presence of a base, in a reaction known as the Darzens condensation. Long-term, high-dose studies in rats have demonstrated that ethyl methylphenylglycidate has no significant adverse health effects and is not carcinogenic. The US Food and Drug Administration has classified ethyl methylphenylglycidate as generally recognized as safe (GRAS). Ethyl methylphenylglycidate Ethyl methylphenylglycidate, commonly known as "strawberry aldehyde", is an organic compound used in the flavor industry in artificial fruit flavors, in particular strawberry. Because of its pleasant taste and aroma, ethyl methylphenylglycidate finds use in