Femur the medial, gives attachment to the fibular collateral ligament of the knee-joint. The femur develops from the limb buds as a result of interactions between the ectoderm and the underlying mesoderm, formation occurs roughly around the fourth week of development. By the sixth week of development, the first hyaline cartilage model of the femur is formed by chondrocytes. Endochondral ossification begins by the end of the embryonic period and primary ossification centers are present in all long bones of the limbs, including the femur, by the 12th week of development. The hindlimb development lags behind forelimb development by 1–2 days.
Tibia Clausa Tibia Clausa A Tibia Clausa is a type of pipe organ pipe. It is a large-scale, stopped wood flute pipe, usually with a leathered lip. The rank was invented by Robert Hope-Jones. Tibia Clausas provides the basic foundation tone of the organ with few overtones or harmonics. The Tibia Clausa is arguably the most important rank of pipes in a theatre pipe organ, with some organs having as many as 5. The stop shares similarities with the "Bourdon" and the "Gedackt" found in some church pipe organs. In the 18th and 19th centuries, Tibia Clausa was sometimes used as an