Inner ear most, while in high frequency sounds, the base of the membrane moves most. Interference with or infection of the labyrinth can result in a syndrome of ailments called labyrinthitis. The symptoms of labyrinthitis include temporary nausea, disorientation, vertigo, and dizziness. Labyrinthitis can be caused by viral infections, bacterial infections, or physical blockage of the inner ear. Another condition has come to be known as autoimmune inner ear disease (AIED). It is characterized by idiopathic, rapidly progressive, bilateral sensorineural hearing loss. It is a fairly rare disorder while at the same time, a lack of proper diagnostic testing has meant that
Refsum disease acid metabolism in the liver of mice. Individuals with Refsum disease present with neurologic damage, cerebellar degeneration, and peripheral neuropathy. Onset is most commonly in childhood/adolescence with a progressive course, although periods of stagnation or remission occur. Symptoms also include ataxia, scaly skin (ichthyosis), difficulty hearing, and eye problems including retinitis pigmentosa, cataracts, and night blindness. In 80% of patients diagnosed with Refsum disease, sensorineural hearing loss has been reported. This is hearing loss as the result of damage to the inner ear or the nerve connected to ear to the brain. Refsum disease is a peroxisomal disorder caused by