Electric current with respect to ground. Ohm's law states that the current through a conductor between two points is directly proportional to the potential difference across the two points. Introducing the constant of proportionality, the resistance, one arrives at the usual mathematical equation that describes this relationship: where "I" is the current through the conductor in units of amperes, "V" is the potential difference measured "across" the conductor in units of volts, and "R" is the resistance of the conductor in units of ohms. More specifically, Ohm's law states that the "R" in this relation is constant, independent of the current. In
Transepithelial potential difference increased in cystic fibrosis, making it a potential diagnostic tool for this disorder. In the kidney, TEPD contributes to tubular reabsorption. Transepithelial potential difference Transepithelial potential difference (TEPD) is the voltage across an epithelium, and is the sum of the membrane potentials for the outer and inner cell membranes. The diagnosis of Cystic Fibrosis (CF) is usually based on high sweat chloride concentrations, characteristic clinical findings (including sinopulmonary infections), and/or family history. However, a small portion of patients with Cystic Fibrosis especially those with "mild" mutations of the Cystic Fibrosis Transmembrane Regulator ion channel (CFTR), have near-normal sweat tests. In