Ethyl cyanohydroxyiminoacetate Ethyl cyanohydroxyiminoacetate Ethyl cyanohydroxyiminoacetate (oxyma) is the oxime of ethyl cyanoacetate and finds use as an additive for carbodiimides, such as dicyclohexylcarbodiimide (DCC) in peptide synthesis. It acts as a neutralizing reagent for the basicity or nucleophilicity of the DCC due to its pronounced acidity (pKa 4.60) and suppresses base catalyzed side reactions, in particular racemization. Ethyl cyanohydroxyiminoacetate is obtained in the reaction of ethyl cyanoacetate and nitrous acid (from sodium nitrite and acetic acid) in 87% yield. Because of the rapid hydrolysis of the ester, the reaction should be carried out at pH 4.5, in buffered phosphoric acid the
Sodium ethyl xanthate Australia, one resulted in evacuation of 100 people and hospitalization of 6 workers who were exposed to the fumes. In another accident, residents of the spillage area complained of headache, dizziness and nausea. Consequently, during high-risk sodium ethyl xanthate handling operations, workers are required by the Australian regulations to be equipped with protective clothing, anti-static gloves, boots and full-face respirators or self-contained breathing apparatus. Sodium ethyl xanthate Sodium ethyl xanthate (SEX) is an organosulfur compound with the chemical formula CHCHOCSNa. It is a pale yellow powder, which is usually obtained as the dihydrate. Sodium ethyl xanthate is used in the