Heart Motu Cordis" (1628) by the English physician William Harvey. Harvey's book completely describes the systemic circulation and the mechanical force of the heart, leading to an overhaul of the Galenic doctrines. Otto Frank (1865–1944) was a German physiologist; among his many published works are detailed studies of this important heart relationship. Ernest Starling (1866–1927) was an important English physiologist who also studied the heart. Although they worked largely independently, their combined efforts and similar conclusions have been recognized in the name "Frank–Starling mechanism". Although Purkinje fibers and the bundle of His were discovered as early as the 19th century, their
I, being born a woman and distressed from artificial constraints, legal or social, or their psychological residue, jealousy." Rather than interpreting the conflict of the poem as an interpersonal one, some critics view the conflict as an internalized "battle of blood against brain." The body may "cloud the mind" of the speaker, but her "staggering brain" loses to her own "stout blood," not to her lover's moves in some sexual contest (Millay 7, 10). By positioning the woman as subject, not object, Millay simultaneously fulfills and subverts the conventions of the sonnet. I, being born a woman and distressed "I, being born a woman and distressed" is