Berkeley Hundred and 17 days before the Pilgrims arrived aboard the "Mayflower" at Plymouth, Massachusetts to establish their Thanksgiving Day in 1621. On March 22, 1622, Opchanacanough, head of the Powhatan Confederacy, began the Second Anglo-Powhatan War with a coordinated series of attacks against English settlements along the James River, known in English histories as the Indian massacre of 1622. Nine colonists were killed at Berkeley. The assault took a heavier toll elsewhere, killing about a third of all the colonists, and virtually wiping out Wolstenholme Towne on Martin's Hundred and Sir Thomas Dale's progressive development and new college at Henricus. Jamestown
Spanish missions in Florida Father Luis de Cancer and three other Dominicans to Tampa Bay was the first solely missionary effort attempted in "La Florida". It ended in failure after six weeks with de Cancer's death at the hands of the Tocobaga natives, which sent shock waves through the Dominican missionary community in New Spain for many years. The first Spanish missions to the Indians of Florida, starting with the foundation of St. Augustine in 1565, were attached to presidios. Between 1559 and 1567, ten presidios were established at major harbors from Port Royal Sound in modern South Carolina to Pensacola Bay on the