Ethyl acetate Fischer equilibrium mentioned above. In the laboratory, and usually for illustrative purposes only, ethyl esters are typically hydrolyzed in a two-step process starting with a stoichiometric amount of a strong base, such as sodium hydroxide. This reaction gives ethanol and sodium acetate, which is unreactive toward ethanol: The rate constant is 0.111 L/mol·s at 25 °C. The for rats is 5620 mg/kg, indicating low toxicity. Given that the chemical is naturally present in many organisms, there is little risk of toxicity. Overexposure to ethyl acetate may cause irritation of the eyes, nose, and throat. Severe overexposure may cause weakness, drowsiness,
Ethyl cyanoacrylate Ethyl cyanoacrylate is prepared by the condensation of formaldehyde with ethyl cyanoacetate:<chem>CH2 (C#N) CO2 Et + CH2O -> CH2=C (C#N) CO2 Et + H2O</chem>This exothermic reaction affords the polymer, which is subsequently sintered, thermally "cracked" to give the monomer. Alternatively, it can be prepared by the ethoxycarbonylation of cyanoacetylene. Ethyl cyanoacrylate is used for gluing various materials. It is also used in medicine, for liquid bandages and for suture-less surgery, but it is used less often than the less toxic "n"-butyl and octyl cyanoacrylates. Off-the-shelf non-medical-grade glues are unsuitable for medical applications, as they may contain solvents (e.g. methyl alcohol)