Heart Motu Cordis" (1628) by the English physician William Harvey. Harvey's book completely describes the systemic circulation and the mechanical force of the heart, leading to an overhaul of the Galenic doctrines. Otto Frank (1865–1944) was a German physiologist; among his many published works are detailed studies of this important heart relationship. Ernest Starling (1866–1927) was an important English physiologist who also studied the heart. Although they worked largely independently, their combined efforts and similar conclusions have been recognized in the name "Frank–Starling mechanism". Although Purkinje fibers and the bundle of His were discovered as early as the 19th century, their
Barbara and the Browns leased to Stax Records. The record rose to # 97 on the "Billboard" Hot 100 during a period when no R&B chart was being published. Stax released two more singles by the group, "In My Heart" and "I Don't Want Trouble" in 1964-65, but neither were commercially successful. The group were then signed by Gene Lucchesi to the XL label, who recorded the group - and, then, Barbara as a solo artist - using producer Charles Chalmers. Several singles were released on the Cadet, Atco and Tower labels, and on XL itself. Although subsequently highly regarded by critics and aficionados