Ménière's disease Ménière's disease Ménière's disease (MD) is a disorder of the inner ear that is characterized by episodes of feeling like the world is spinning (vertigo), ringing in the ears (tinnitus), hearing loss, and a fullness in the ear. Typically only one ear is affected, at least initially; however, over time both ears may become involved. Episodes generally last from 20 minutes to a few hours. The time between episodes varies. Over time the hearing loss and ringing in the ears may become constant. The cause of Ménière's disease is unclear but likely involves both genetic and environmental factors. A number
Stereocilia (inner ear) to tiny springs, which, when stretched, open cation selective channels thus allowing ions to flow across the cell membrane into the hair cells. They also are involved in the force transmission across the bundle and the maintenance of the hair bundle structure. As acoustic sensors in mammals, stereocilia are lined up in the organ of Corti within the cochlea of the inner ear. In hearing, stereocilia transform the mechanical energy of sound waves into electrical signals for the hair cells, which ultimately leads to an excitation of the auditory nerve. Stereocilia are composed of cytoplasm with embedded bundles of cross-linked