Catherine Howard Lord Edmund Howard ( – 1539) and Joyce Culpeper ( – ). Her father's sister, Elizabeth Howard, was the mother of Anne Boleyn. Therefore, Catherine Howard was the first cousin of Anne Boleyn, and the first cousin once removed of Lady Elizabeth (later Queen Elizabeth I), Anne's daughter by Henry VIII. As a granddaughter of Thomas Howard, 2nd Duke of Norfolk (1443–1524), Catherine had an aristocratic pedigree. Her father was not wealthy, being a younger son among 21 children and disfavoured in the custom of primogeniture, by which the eldest son inherits all his father's estate. When Catherine's parents married,
Catherine of Siena court and writing letters to persuade others. For many years she had accustomed herself to a rigorous abstinence. She received the Holy Eucharist almost daily. This extreme fasting appeared unhealthy in the eyes of the clergy and her own sisterhood. Her confessor, Blessed Raymond, ordered her to eat properly. But Catherine claimed that she was unable to, describing her inability to eat as an "infermità" (illness). From the beginning of 1380, Catherine could neither eat nor swallow water. On February 26 she lost the use of her legs. Catherine died in Rome, on 29 April 1380, at the age of