The Description of the Human Body He believed the heat of the heart somehow caused all movement of the body. Blood vessels he realized were pipes, he saw that veins carried digested food to the heart. (This was brought further by William Harvey. Harvey developed the idea of the circulation of the blood.) Descartes felt that an energetic part of blood went to the brain and there gave the brain a special type of air imbued with vital force that enabled the brain to experience, think and imagine. This special air then went through the nerves to the muscles enabling them to move. The Description of
Nanoparticles for drug delivery to the brain treatment of various diseases. For example, one study has shown that using focused ultrasound with oscillating bubbles loaded with a chemotherapeutic drug, carmustine, facilitates the safe treatment of glioblastoma in an animal model. This drug, like many others, normally requires large dosages to reach the target brain tissue diffusion from the blood, leading to systemic toxicity and the possibilities of multiple harmful side effects manifesting throughout the body. However, focused ultrasound has the potential to increase the safety and efficacy of drug delivery to the brain. A study was performed to assess the toxicity effects of doxorubicin-loaded polymeric nanoparticle systems.