Femur the medial, gives attachment to the fibular collateral ligament of the knee-joint. The femur develops from the limb buds as a result of interactions between the ectoderm and the underlying mesoderm, formation occurs roughly around the fourth week of development. By the sixth week of development, the first hyaline cartilage model of the femur is formed by chondrocytes. Endochondral ossification begins by the end of the embryonic period and primary ossification centers are present in all long bones of the limbs, including the femur, by the 12th week of development. The hindlimb development lags behind forelimb development by 1–2 days.
Stifle joint the joint into two functional units—the 'femoromeniscal joint' for flexion/extension movements and the 'meniscotibial joint' for rotation—a function analogous to that of the disc dividing the temporomandibular (jaw) joint. The menisci also contain nerve endings which are used to assist in proprioreception. The menisci are attached via a variety of ligaments: two meniscotibial ligaments for each meniscus, the meniscofemoral from the lateral meniscus to the femur, the meniscocollateral from the medial meniscus to the medial collateral ligament, and the transverse ligament (or intermeniscal) which runs between the two menisci. There are between one and four sesamoid bones associated with the