Vogt–Koyanagi–Harada disease Vogt–Koyanagi–Harada disease Vogt–Koyanagi–Harada disease (VKH), also known as Vogt–Koyanagi–Harada syndrome, uveomeningitis syndrome and uveomeningoencephalitic syndrome, is a multisystem disease of presumed autoimmune cause, that affects pigmented tissues, which have melanin. The most significant manifestation is bilateral, diffuse uveitis, which affects the eye. VKH may variably also involve the inner ear with effects on hearing, the skin, and the meninges of the central nervous system. The disease is characterised by bilateral diffuse uveitis, with pain, redness and blurring of vision. The eye symptoms may be accompanied by a varying constellation of systemic symptoms, such as auditory (tinnitus, vertigo, and hypoacusis), neurological
Body part as an object aphasics have been put forward since then, including intellectual degradation, and the inability to carry out pretended actions. Denny-Brown takes a more holistic approach and suggested ideational apraxia results from diffuse brain damage. Body part as object is a relatively new concept in scientific literature. Past studies have suggested that BPO pantomimes may allow aphasics to avoid an impaired cognitive function. By not having to reproduce a movement outside of the usual context, they can have a more vivid experience of acting on an object. What is known as BPO pantomiming in children was first discussed in Goodglass and Kaplan’s