Holby City cast as Greg Douglas in series twelve. "Holby City" and "Casualty" are both set in Holby City Hospital, in the fictional county of Wyvern, in the southwest of England close to the Welsh border. The city exterior is represented by Bristol, though "Holby City" is filmed at BBC Elstree Centre in Borehamwood, Hertfordshire. The "Casualty" set in Bristol was not large enough to encompass the surgical ward and operating theatre required for "Holby City", and as a result, some crossover scenes in the first episode had to be shot twice, first on the "Casualty" set and then again at Elstree,
Holby City describing real nursing work in contrast as "very post-watershed". In November 2009, Antony Sumara, CEO of the Mid Staffordshire NHS Foundation Hospital Trust, wrote a column criticising "Holby City" for misrepresenting real hospital life. Tom Sutcliffe of "The Independent" reviewed a December 2009 episode poorly, finding it "astonishing" that any patients leave Holby General alive, as the staff are "so busy looking stricken or lovelorn at each other". In December 2003, "The Times" Libby Purves wrote a critical opinion piece, observing that "Holby City" medical staff are often depicted getting drunk in clubs, but afterwards are able to function properly