Vogt–Koyanagi–Harada disease Vogt–Koyanagi–Harada disease Vogt–Koyanagi–Harada disease (VKH), also known as Vogt–Koyanagi–Harada syndrome, uveomeningitis syndrome and uveomeningoencephalitic syndrome, is a multisystem disease of presumed autoimmune cause, that affects pigmented tissues, which have melanin. The most significant manifestation is bilateral, diffuse uveitis, which affects the eye. VKH may variably also involve the inner ear with effects on hearing, the skin, and the meninges of the central nervous system. The disease is characterised by bilateral diffuse uveitis, with pain, redness and blurring of vision. The eye symptoms may be accompanied by a varying constellation of systemic symptoms, such as auditory (tinnitus, vertigo, and hypoacusis), neurological
Tinnitus masker 1970s by Dr. Jack Vernon, when he reported that white noise was effective in alleviating tinnitus. Tinnitus suppression is different than but related to tinnitus masking. It is an acoustic or neurological effect that results in temporary suppression of tinnitus by listening to an appropriately tailored sound for a short period. After the sound is withdrawn, tinnitus may be fully (complete silence) or partially suppressed. Most (70–90%) of persons can experience the effect. There is usually a period of complete silence followed by a gradual return of tinnitus to its original level. The effect lasts for 5 minutes or less