History of malaria and brain which are the most constant post-mortem indications of chronic malaria infection. He related the prevalence of malaria in swampy areas to the presence of flies and recommended swamp drainage to prevent it. In the nineteenth century, the first drugs were developed to treat malaria and parasites were first identified as its source. French chemist Pierre Joseph Pelletier and French pharmacist Joseph Bienaimé Caventou separated in 1820 the alkaloids cinchonine and quinine from powdered fever tree bark, allowing for the creation of standardized doses of the active ingredients. Prior to 1820, the bark was simply dried, ground to a
But what about the noise of crumpling paper which he used to do in order to paint the series of "Papiers froissés" or tearing up paper to make "Papiers déchirés?" Arp was stimulated by water (sea, lake, and flowing waters like rivers), forests made of wood, metal and glass, "O" is the sound of pouring or bubbling in water and crumpling and tearing paper, and "(" and ")" are also these sounds but cut in half, that is, sounded twice and always for the same length of time. Given the indeterminate nature of this composition, each performance tends to feature distinct traits, and the main performer is often credited for "realizing" the piece. The following is a partial list of recordings of this piece: But what about the noise of crumpling paper which he used to do in order to paint the series