Adrenaline of epinephrine can be seen in autonomic neuropathy or following adrenalectomy. Failure of the adrenal cortex, as with Addisons disease, can suppress epinephrine secretion as the activity of the synthesing enzyme, phenylethanolamine-"N"-methyltransferase, depends on the high concentration of cortisol that drains from the cortex to the medulla. In 1901, Jokichi Takamine patented a purified extract from the adrenal glands, and called it "adrenalin" (from the Latin for "on top of the kidneys" ("ad" and "renal"), which was trademarked by Parke, Davis & Co in the US. The British Approved Name and European Pharmacopoeia term for this drug is hence "adrenaline".
Cortex Plus Role Playing Game, and Marvel Heroic Roleplaying won the 2013 award and the award for best support as well as the 2012 ENnie Award for Best Rules and runner up for Best Game. Note that despite the similarity in name, "Cortex Plus" is not the Cortex System, also produced by Margaret Weis Productions. Unlike the Cortex System, Cortex Plus is a roll and keep system in which you roll one die from each category and keep the two highest dice in your dice pool. What goes into your dice pool is whatever is considered important for the game you are