Copper for treatment of Wilson's disease have been investigated for use in cancer therapy. Copper is an essential trace element in plants and animals, but not all microorganisms. The human body contains copper at a level of about 1.4 to 2.1 mg per kg of body mass. Copper is absorbed in the gut, then transported to the liver bound to albumin. After processing in the liver, copper is distributed to other tissues in a second phase, which involves the protein ceruloplasmin, carrying the majority of copper in blood. Ceruloplasmin also carries the copper that is excreted in milk, and is particularly
Brain-to-body mass ratio highest for an invertebrate, although some ant species have 14%-15% of their mass in their brains, the highest value known for any animal. Sharks have one of the highest for fish alongside manta rays (although the electrogenic elephantfish has a ratio nearly 80 times higher - about 1/32, which is slightly higher than that for humans). Treeshrews have a higher brain to body mass ratio than any other mammal, including humans. Shrews hold about 10% of their body mass in their brain. It is a trend that the larger the animal gets, the smaller the brain-to-body mass ratio is. Large