Steam digester Torricelli and further developed by German scientist Otto von Guericke with his Magdeburg hemispheres. Guerike's demonstration was documented by Gaspar Schott, in a book that was read by Robert Boyle. Boyle and his assistant Robert Hooke improved Guericke's air pump design and built their own. From this, through various experiments, they formulated what is called Boyle's law, which states that the volume of a body of an ideal gas is inversely proportional to its pressure. Soon the ideal gas law was formulated. Based on these concepts in 1679 a Boyle's associate, named Denis Papin, built a "bone digester", which is
Pulse pressure Pulse pressure Pulse pressure is the difference between the systolic and diastolic blood pressure. It is measured in millimeters of mercury (mmHg). It represents the force that the heart generates each time it contracts. For example, if resting blood pressure is 120/80 mmHg, then the pulse pressure is 40 mmHg. Pulse pressure is the (higher) systolic blood pressure minus the (lower) diastolic blood pressure. The systemic pulse pressure is approximately proportional to stroke volume, or the amount of blood ejected from the left ventricle during systole (pump action) and inversely proportional to the compliance (similar to Elasticity) of the aorta.