Tonic water by mass), while the daily therapeutic dose of quinine is in the range of 500–1000 mg, and 10 mg/kg every eight hours for effective malaria prevention (2100 mg daily for a 70 kg adult). Still, it is often recommended as a relief for leg cramps but medical research suggests some care is needed in monitoring doses. Because of quinine's risks, the FDA cautions consumers against using "off-label" quinine drugs to treat leg cramps. Tonic water is often used as a drink mixer for cocktails, especially gin and tonic. Vodka tonic is also popular. Tonic water with lemon or lime flavor
The Iron Tonic 19th-century-engraving style, the work comprises 14 panels of illustration and rhyming text in iambic pentameter. It tells the story of an eerie, melancholy manor whose inhabitants are either old or unwell. Wim Tigges described the book as "a compilation of hardly related couplets," in which nonsense objects "are seen to be falling unaccountably out of the sky." Tigges notes it uses a device commonly used in Gorey's writing, "the unexplained recurrence of an irrelevant object". The Iron Tonic The Iron Tonic: Or, A Winter Afternoon in Lonely Valley is a Surrealist country-house mystery—that is, a series of clues that don't