Gin and tonic plasma levels at the lower limit of therapeutic efficacy and may, in fact, cause transitory suppression of parasites". This method of consumption of quinine was impractical for malaria prophylaxis, as the amount of drug needed "can not be maintained with even large amounts of tonic". The authors conclude that it is not an effective form of treatment for malaria. In Spain, a variation on the drink called Gin-Tonic has become popular. This differs from a traditional gin and tonic as it is served in a balloon glass (copa de balon) or coupe glass with plenty of ice and a garnish
History of malaria bites, is unknown. The presence of malaria in Egypt from circa 800 BCE onwards has been confirmed using DNA-based methods. Malaria became widely recognized in ancient Greece by the 4th century BCE, and is implicated in the decline of many city-state populations. The term "μίασμα" (Greek for miasma): "stain, pollution", was coined by Hippocrates of Kos who used it to describe dangerous fumes from the ground that are transported by winds and can cause serious illnesses. Hippocrates (460–370 BCE), the "father of medicine", related the presence of intermittent fevers with climatic and environmental conditions and classified the fever according to