Hepatitis In hemochromatosis, excess amounts of iron accumulate in multiple body sites, including the liver, which can lead to cirrhosis. In Wilson's disease, excess amounts of copper accumulate in the liver and brain, causing cirrhosis and dementia. When the liver is involved, alpha-1-antitrypsin deficiency and Wilson's disease tend to present as hepatitis in the neonatal period or in childhood. Hemochromatosis typically presents in adulthood, with the onset of clinical disease usually after age 50. Ischemic hepatitis (also known as shock liver) results from reduced blood flow to the liver as in shock, heart failure, or vascular insufficiency. The condition is most
Brain-to-body mass ratio animals usually have larger brains than smaller animals); the relationship is not, however, linear. Small mammals such as mice may have a brain/body ratio similar to humans, while elephants have a comparatively lower brain/body ratio. In animals, it is thought that the larger the brain, the more brain weight will be available for more complex cognitive tasks. However, large animals need more neurons to represent their own bodies and control specific muscles; thus, relative rather than absolute brain size makes for a ranking of animals that better coincides with the observed complexity of animal behaviour. The relationship between brain-to-body mass