Science and invention in Birmingham 1054 Mk XVIs) had been built. CBAF became the largest and most successful plant of its type during the 1939–45 conflict. As the largest Spitfire factory in the UK, by producing up to 320 aircraft per month, it built over half of the approximately 20,000 aircraft of this type. 1944: Anthony Ernest Pratt takes out his first patent for a board game named 'Murder', this is later to become the world-renowned murder mystery game 'Cluedo'. 1946: Chance Brothers produce the first all-glass syringe with interchangeable barrel and plunger, thereby allowing mass sterilisation of components without the need for matching them.
Orient Express (board game) Orient Express (board game) Orient Express is a crime fiction board game published by Jumbo and Just Games. The game is based on the book "Murder on the Orient Express" by Agatha Christie. The game was designed by Jeff Smets and released in 1985. The game contains 10 different murder cases, each of which can be played only once. Five new plots were released in 1987. The game is set on the train Orient Express, going from Paris to Istanbul. The players сhoose one case among the 10 possible cases. On each case a murder has been committed by one