History of malaria fever with quinine, the effects of both syphilis and malaria could be minimized. While about 15% of patients died from malaria, this was preferable to the almost-certain death from syphilis. Therapeutic malaria opened up a wide field of chemotherapeutic research and was practised until 1950. Wagner-Jauregg was awarded the 1927 Nobel Prize in Physiology or Medicine for his discovery of the therapeutic value of malaria inoculation in the treatment of dementia paralytica. Henry Heimlich advocated malariotherapy as a treatment for AIDS, and some studies of malariotherapy for HIV infection have been performed in China. The United States Centers for Disease
Tonic Trouble The only remnants of that game were found to be pieces of concept art created by Ubi Soft artist Yann Jouette. "Tonic Trouble" was met with mixed reception upon release, according to review aggregator GameRankings. "Tonic Trouble" sold 1.1 million copies as of 2001. "Electronic Gaming Monthly" thought that, in terms of level design, "Tonic Trouble" was "a tightly developed platformer"; the control scheme was similarly praised. "Game Informer" wrote that the "wide variety" of gameplay and "solid" controls would be enjoyable to platformer fans. "GamePro" commended the musical score and sound effects, noting the puzzles as what kept the