Cowpox to the mild form of smallpox and the observation that dairy farmers were immune from smallpox inspired the first smallpox vaccine, created and administered by English physician Edward Jenner. The word “vaccination,” coined by Jenner in 1796, is derived from the Latin root "vaccinus", meaning of or from the cow. Once vaccinated, a patient develops antibodies that make them immune to cowpox, but they also develop immunity to the smallpox virus, or "Variola virus". The cowpox vaccinations and later incarnations proved so successful that in 1980, the World Health Organization announced that smallpox was the first disease to be eradicated
Smallpox demon parts of India, China, Africa and Latin America, sacrifices were made to appease the gods of smallpox. In medieval Europe, prayer and pious living were recommended as one way to guard against sickness. Many Japanese textbooks on dermatology stated that red light was able to weaken the symptoms of smallpox. This was common in China, India, Turkey and Georgia. In western Africa, the Yoruba god of smallpox, Sopona, was associated with the color red. The red treatment was given scientific authority by Finsen, who claimed that the treatment of smallpox patients with red light reduced the severity of scarring, and