History of malaria millennium BCE in Greece and China. For thousands of years, traditional herbal remedies have been used to treat malaria. The first effective treatment for malaria came from the bark of cinchona tree, which contains quinine. After the link to mosquitos and their parasites were identified in the early twentieth century, mosquito control measures such as widespread use of the insecticide DDT, swamp drainage, covering or oiling the surface of open water sources, indoor residual spraying and use of insecticide treated nets was initiated. Prophylactic quinine was prescribed in malaria endemic areas, and new therapeutic drugs, including chloroquine and artemisinins, were
Tonic Trouble The only remnants of that game were found to be pieces of concept art created by Ubi Soft artist Yann Jouette. "Tonic Trouble" was met with mixed reception upon release, according to review aggregator GameRankings. "Tonic Trouble" sold 1.1 million copies as of 2001. "Electronic Gaming Monthly" thought that, in terms of level design, "Tonic Trouble" was "a tightly developed platformer"; the control scheme was similarly praised. "Game Informer" wrote that the "wide variety" of gameplay and "solid" controls would be enjoyable to platformer fans. "GamePro" commended the musical score and sound effects, noting the puzzles as what kept the