Calcium-induced calcium release of CICR across the cell causes the significant increase in cytosolic Ca that is important in activating muscle contraction. Calcium-induced calcium release Calcium-induced calcium release (CICR) describes a biological process whereby calcium is able to activate calcium release from intracellular Ca stores (e.g., endoplasmic reticulum or sarcoplasmic reticulum). Although CICR was first proposed for skeletal muscle in the 1970s, it is now known that CICR is unlikely to be its primary mechanism for activating SR calcium release. Instead, CICR is thought to be crucial for excitation-contraction coupling in cardiac muscle and it is now obvious that CICR is a widely
Calcium coating in moist air, but below 30% relative humidity it may be stored indefinitely at room temperature. Besides the simple oxide CaO, the peroxide CaO can be made by direct oxidation of calcium metal under a high pressure of oxygen, and there is some evidence for a yellow superoxide Ca(O). Calcium hydroxide, Ca(OH), is a strong base, though it is not as strong as the hydroxides of strontium, barium or the alkali metals. All four dihalides of calcium are known. Calcium carbonate (CaCO) and calcium sulfate (CaSO) are particularly abundant minerals. Like strontium and barium, as well as the alkali