Virology in order to immunize others. In 1717 Lady Mary Wortley Montagu observed the practice in Istanbul and attempted to popularize it in Britain, but encountered considerable resistance. In 1796 Edward Jenner developed a much safer method, using cowpox to successfully immunize a young boy against smallpox, and this practice was widely adopted. Vaccinations against other viral diseases followed, including the successful rabies vaccination by Louis Pasteur in 1886. The nature of viruses however was not clear to these researchers. In 1892, the Russian biologist Dmitry Ivanovsky used a Chamberland filter to try to isolate the bacteria that caused tobacco mosaic
1775–82 North American smallpox epidemic public. These measures included the refusal to allow contact between his soldiers and the viral refugees of Boston. Additionally, certain retreats of the Continental Army can be linked to Washington's wish to avoid smallpox and his intense caution when it came to his troops. Though it was practiced in many parts of the world, the technology of inoculation, or Variolation, was not known in Europe until the 1700s. It was widely publicized by Lady Mary Wortley Montagu, who inoculated her own children against smallpox, despite widespread concern and controversy. Inoculation was the practice of introducing infected materials in to the