Cheers Cheers Cheers is an American sitcom that ran on NBC from September 30, 1982, to May 20, 1993, with a total of 275 half-hour episodes for eleven seasons. The show was produced by Charles/Burrows/Charles Productions in association with Paramount Network Television. The show was created by the team of James Burrows, Glen Charles, and Les Charles. The show is set in a bar named Cheers in Boston, Massachusetts, where a group of locals meet to drink, relax, and socialize. The show's main theme song, co-written and performed by Gary Portnoy, lent its refrain "Where Everybody Knows Your Name" as the
Daniel A. Portnoy for the induction of cell-mediated immunity. Both Drs. Paterson and Portnoy went on to work with biotech companies to develop vaccines for both cancer and infectious disease applications. Numerous clinical trials based on their discoveries have shown promising results as immunotherapeutic treatments for cancer. In 1997, Dr Portnoy moved to UC Berkeley where his lab continues to examine fundamental aspects of "L. monocytogenes" biology, and has expanded to focus on both innate and acquired immunity in the context of Listeria infection. Dr. Portnoy and collaborators have shown that immune cells recognize cyclic di-AMP, a novel and essential bacterial signaling molecule,