Calcium-induced calcium release Calcium-induced calcium release Calcium-induced calcium release (CICR) describes a biological process whereby calcium is able to activate calcium release from intracellular Ca stores (e.g., endoplasmic reticulum or sarcoplasmic reticulum). Although CICR was first proposed for skeletal muscle in the 1970s, it is now known that CICR is unlikely to be its primary mechanism for activating SR calcium release. Instead, CICR is thought to be crucial for excitation-contraction coupling in cardiac muscle and it is now obvious that CICR is a widely occurring cellular signaling process present even in many non-muscle cells, e.g. in the insulin-secreting pancreatic beta cells and many
Calcium iodide Calcium iodide Calcium iodide (chemical formula CaI) is the ionic compound of calcium and iodine. This colourless deliquescent solid is a salt that is highly soluble in water. Its properties are similar to those for related salts, such as calcium chloride. It is used in photography. It is also used in cat food as a source of iodine. Henri Moissan first isolated pure calcium in 1898 by reducing calcium iodide with pure sodium metal: Calcium iodide can be formed by treating calcium carbonate, calcium oxide, or calcium hydroxide with hydroiodic acid: Calcium iodide slowly reacts with oxygen and carbon dioxide