Atom to the positively charged nucleus by the attraction created from opposite electric charges. If an atom has more or fewer electrons than its atomic number, then it becomes respectively negatively or positively charged as a whole; a charged atom is called an ion. Electrons have been known since the late 19th century, mostly thanks to J.J. Thomson; see history of subatomic physics for details. Protons have a positive charge and a mass 1,836 times that of the electron, at . The number of protons in an atom is called its atomic number. Ernest Rutherford (1919) observed that nitrogen under alpha-particle
Atom economy yield, because a high-yielding process can still result in substantial byproducts. Examples include the Cannizzaro reaction, in which approximately 50% of the reactant aldehyde becomes the other oxidation state of the target; the Wittig reaction, which uses high-mass phosphorus reagents that ultimately become waste; and the Gabriel synthesis, which produces a stoichiometric quantity of phthalic acid If the desired product has an enantiomer the reaction needs to be sufficiently stereoselective even when atom economy is 100%. A Diels-Alder reaction is an example of a potentially very atom efficient reaction that also can be chemo-, regio-, diastereo- and enantioselective. Catalytic hydrogenation