History of malaria fever with quinine, the effects of both syphilis and malaria could be minimized. While about 15% of patients died from malaria, this was preferable to the almost-certain death from syphilis. Therapeutic malaria opened up a wide field of chemotherapeutic research and was practised until 1950. Wagner-Jauregg was awarded the 1927 Nobel Prize in Physiology or Medicine for his discovery of the therapeutic value of malaria inoculation in the treatment of dementia paralytica. Henry Heimlich advocated malariotherapy as a treatment for AIDS, and some studies of malariotherapy for HIV infection have been performed in China. The United States Centers for Disease
Tonic Trouble Stahl, Casamassina found there to be too few sound effects. Reviewing the game on PC, Vincent Lopez of "IGN" compared the game to "Rayman 2" like Casamassina, faulting "Tonic Trouble" for being too much like past platformers. The camera was subject to reproval for how it would inherently worsen the gameplay experience, adding to his dissatisfaction with the "wonky" controls. Jones derided the game's "shamelessly derivative" nature. "Nintendo Power" complained about certain areas where "hit detection" failed to give effect. Tonic Trouble Tonic Trouble is an action-adventure game developed by Ubi Soft Montreal and published by Ubi Soft. Conceptualized by