Gin and tonic with Hendrick's Gin is typically garnished with a slice of cucumber. However, garnishes of cucumber are very rare, and garnishes of orange are rarer still. The cocktail was introduced by the army of the British East India Company in India. In India and other tropical regions, malaria was a persistent problem. In the 1700s it was discovered by Scottish doctor George Cleghorn that quinine could be used to prevent and treat the disease. The quinine was drunk in tonic water, however the bitter taste was unpleasant. British officers in India in the early 19th century took to adding a mixture
Clausena anisata half maximal effective concentration (EC50) value was 74 μg/mL. The authors concluded that these results encourage further investigation of the use of this plant as complementary treatment options for ascariasis. This species is used in treating an uncommonly wide range of ailments and conditions. Decoctions of the leaves or roots are taken for gastro-intestinal disorders, fever, pneumonia, headache, hypotension, sore throat and sinusitis, venereal diseases, as an aphrodisiac and anthelmintic, as a tonic for pregnant women, and as a tonic for infants to prevent rickets and to control convulsions. Root decoctions and infusions are also taken for whooping cough, malaria,