Smallpox vaccine Smallpox vaccine Smallpox vaccine, the first successful vaccine to be developed, was introduced by Edward Jenner in 1796. He followed up his observation that milkmaids who had previously caught cowpox did not later catch smallpox by showing that inoculated cowpox protected against inoculated smallpox. Dryvax is a freeze-dried calf lymph smallpox vaccine. It is the world's oldest smallpox vaccine, created in the late 19th century by American Home Products, a predecessor of Wyeth. By the 1940s, Wyeth was the leading US manufacturer of the vaccine and the only manufacturer by the 1960s. After world health authorities declared smallpox had been
History of smallpox in Mexico 1799. Viceroy Miguel José de Azanza, ordered an article written on 14 November 1799 about the benefits resulting from the inoculation in the 1790s epidemic and distributed to the population. In 1803, Spanish doctor Francisco Javier Balmis started a vaccination program against smallpox in New Spain, better known as Balmis Expedition, which reduced the severity and mortality in the epidemics that followed. Before Balmis, Dr José María Arboleyda started a vaccination campaign in 1801 but this was not successful. There was another important outbreak in 1814 which started in Veracruz and extended to Mexico City, Tlaxcala and Hidalgo. This epidemic