Tonic water by mass), while the daily therapeutic dose of quinine is in the range of 500–1000 mg, and 10 mg/kg every eight hours for effective malaria prevention (2100 mg daily for a 70 kg adult). Still, it is often recommended as a relief for leg cramps but medical research suggests some care is needed in monitoring doses. Because of quinine's risks, the FDA cautions consumers against using "off-label" quinine drugs to treat leg cramps. Tonic water is often used as a drink mixer for cocktails, especially gin and tonic. Vodka tonic is also popular. Tonic water with lemon or lime flavor
Malaria Day in the Americas El Salvador, and Suriname. Malaria Day in the Americas Malaria Day in the Americas is commemorated annually on November 6 to promote awareness, recognize past and current efforts to prevent and control malaria in the region of the Americas, build commitment, and to mobilize action to advance malaria goals and targets as the region works towards elimination. Awareness of this disease is very important in the region of the Americas, where an estimated 120 million people in 21 endemic countries are at risk of malaria. In 2012, there were 469,000 confirmed malaria cases in the region with 108 deaths. Nonetheless,