Calcium-induced calcium release of CICR across the cell causes the significant increase in cytosolic Ca that is important in activating muscle contraction. Calcium-induced calcium release Calcium-induced calcium release (CICR) describes a biological process whereby calcium is able to activate calcium release from intracellular Ca stores (e.g., endoplasmic reticulum or sarcoplasmic reticulum). Although CICR was first proposed for skeletal muscle in the 1970s, it is now known that CICR is unlikely to be its primary mechanism for activating SR calcium release. Instead, CICR is thought to be crucial for excitation-contraction coupling in cardiac muscle and it is now obvious that CICR is a widely
Calcium chlorate Calcium chlorate Calcium chlorate is the calcium salt of chloric acid, with the chemical formula Ca(ClO). Like other chlorates, it is a strong oxidizer. Calcium chlorate is produced by passing chlorine gas through a hot suspension of calcium hydroxide in water, producing calcium hypochlorite, which disproportionates when heated with excess chlorine to give calcium chlorate and calcium chloride: This is also the first step of the Liebig process for the manufacture of potassium chlorate. In theory, electrolysis of hot calcium chloride solution will give chlorate, analogous to the process used for the manufacture of sodium chlorate. In practice, electrolysis is