Smallpox vaccine Smallpox vaccine Smallpox vaccine, the first successful vaccine to be developed, was introduced by Edward Jenner in 1796. He followed up his observation that milkmaids who had previously caught cowpox did not later catch smallpox by showing that inoculated cowpox protected against inoculated smallpox. Dryvax is a freeze-dried calf lymph smallpox vaccine. It is the world's oldest smallpox vaccine, created in the late 19th century by American Home Products, a predecessor of Wyeth. By the 1940s, Wyeth was the leading US manufacturer of the vaccine and the only manufacturer by the 1960s. After world health authorities declared smallpox had been
Early clashes in the Rhine campaign of 1796 systematically divested of old men who might have tempered the rash impulses of teenagers and young adults. It had already made itself odious, by rumor and action, throughout France. Furthermore, it was an army entirely dependent upon the countryside for its material support. After April 1796, pay was made in metallic value, but pay was still in arrears. Throughout the spring and early summer, the unpaid French army was in almost constant mutiny: in May 1796, in the border town of Zweibrücken, the 74th Demi-brigade revolted. In June, the 17th Demi-brigade was insubordinate (frequently) and in the 84th Demi-brigade, two