Adrenaline of epinephrine can be seen in autonomic neuropathy or following adrenalectomy. Failure of the adrenal cortex, as with Addisons disease, can suppress epinephrine secretion as the activity of the synthesing enzyme, phenylethanolamine-"N"-methyltransferase, depends on the high concentration of cortisol that drains from the cortex to the medulla. In 1901, Jokichi Takamine patented a purified extract from the adrenal glands, and called it "adrenalin" (from the Latin for "on top of the kidneys" ("ad" and "renal"), which was trademarked by Parke, Davis & Co in the US. The British Approved Name and European Pharmacopoeia term for this drug is hence "adrenaline".
International Society for Autonomic Neuroscience International Society for Autonomic Neuroscience The International Society for Autonomic Neuroscience is a scientific society of researchers studying the autonomic nervous system. The society organizes scientific meetings, publishes a scientific journal, and supports students through awards and travel grants. It is a non-profit and non-governmental organization. The society was founded in 1995, because it was felt that the key international society covering neuroscience, the International Brain Research Organization, was not sufficiently representing research on this part of the nervous system. The first president was Geoffrey Burnstock. Elsewhere, it has been claimed that the society originated because of the "Journal of