Gin and tonic with Hendrick's Gin is typically garnished with a slice of cucumber. However, garnishes of cucumber are very rare, and garnishes of orange are rarer still. The cocktail was introduced by the army of the British East India Company in India. In India and other tropical regions, malaria was a persistent problem. In the 1700s it was discovered by Scottish doctor George Cleghorn that quinine could be used to prevent and treat the disease. The quinine was drunk in tonic water, however the bitter taste was unpleasant. British officers in India in the early 19th century took to adding a mixture
Tonic (physiology) joint capsule, muscle spindle and the Ruffini corpuscle. Tonic (physiology) Tonic in physiology refers to a physiological response which is slow and may be graded. This term is typically used in opposition to a fast response. For instance, tonic muscles are contrasted by the more typical and much faster twitch muscles, while tonic sensory nerve endings are contrasted to the much faster phasic sensory nerve endings. Tonic muscles are much slower than twitch fibers in terms of time from stimulus to full activation, time to full relaxation upon cessation of stimuli, and maximal shortening velocity. These muscles are rarely found