Copper for treatment of Wilson's disease have been investigated for use in cancer therapy. Copper is an essential trace element in plants and animals, but not all microorganisms. The human body contains copper at a level of about 1.4 to 2.1 mg per kg of body mass. Copper is absorbed in the gut, then transported to the liver bound to albumin. After processing in the liver, copper is distributed to other tissues in a second phase, which involves the protein ceruloplasmin, carrying the majority of copper in blood. Ceruloplasmin also carries the copper that is excreted in milk, and is particularly
Right hemisphere brain damage shifted to include right hemisphere damage (Brookshire, 2007). It is now well established that language and cognition can be seriously impaired by unilateral right hemisphere brain damage. Specific cognitive tests can help diagnose the existence of right hemisphere brain damage and differentiate symptoms from those of left hemisphere damage. Unlike the aphasias, caused by left hemisphere damage and generally resulting in focused language deficits, right hemisphere brain damage can result in a variety of diffuse deficits which complicate formal testing of this disorder (Brookshire, 2007). These formal tests assess areas such as understanding humor, metaphors, sarcasm, facial expression, and prosody.