Smallpox one-third of the cases resulted in blindness. These deaths included those of four reigning monarchs and a queen consort. In the 20th century smallpox killed 200-300 million people. Edward Jenner discovered in 1798 that vaccination could prevent smallpox. In 1967, the WHO intensified efforts to eliminate the disease. Smallpox is one of two infectious diseases to have been eradicated, the other being rinderpest in 2011. The term "smallpox" was first used in Britain in the 15th century to distinguish the disease from syphilis, which was then known as the "great pox". Other historical names for the disease include pox, speckled
Smallpox demon poetry including 105 poems published in 1805. Traditional smallpox folk dances have been observed even in present-day Japan, including Ibaraki Prefecture and Kagoshima Prefecture, for the avoidance of smallpox devils. In European countries the "red treatment" was practiced from the 12th century onwards; when he caught smallpox, King Charles V of France was dressed in a red shirt, red stockings, and a red veil. Queen Elizabeth I of England was likewise wrapped in a red blanket and placed by a live fire when she fell ill with smallpox in 1562, and similar treatments were applied to other European monarchs. In