Adrenaline of epinephrine can be seen in autonomic neuropathy or following adrenalectomy. Failure of the adrenal cortex, as with Addisons disease, can suppress epinephrine secretion as the activity of the synthesing enzyme, phenylethanolamine-"N"-methyltransferase, depends on the high concentration of cortisol that drains from the cortex to the medulla. In 1901, Jokichi Takamine patented a purified extract from the adrenal glands, and called it "adrenalin" (from the Latin for "on top of the kidneys" ("ad" and "renal"), which was trademarked by Parke, Davis & Co in the US. The British Approved Name and European Pharmacopoeia term for this drug is hence "adrenaline".
Digital nervous system Digital nervous system Digital nervous system is a phrase, popularly associated with Bill Gates of Microsoft, used to describe a vision for how the IT infrastructure of an enterprise could be analogous to the autonomic nervous system of a biological organism. Gates made extensive use of the term in his 1999 book "Business @ the Speed of Thought". The actual phrase "digital nervous system" may not have originated with Gates however, as it has been reported that Judith Dayhoff used the term before Gates did. Steve Ballmer attempted to explain the digital nervous system by saying the following: Gates himself