Adrenaline of epinephrine can be seen in autonomic neuropathy or following adrenalectomy. Failure of the adrenal cortex, as with Addisons disease, can suppress epinephrine secretion as the activity of the synthesing enzyme, phenylethanolamine-"N"-methyltransferase, depends on the high concentration of cortisol that drains from the cortex to the medulla. In 1901, Jokichi Takamine patented a purified extract from the adrenal glands, and called it "adrenalin" (from the Latin for "on top of the kidneys" ("ad" and "renal"), which was trademarked by Parke, Davis & Co in the US. The British Approved Name and European Pharmacopoeia term for this drug is hence "adrenaline".
Nervous system network models the development of nerve cell morphology, cell physiology, cell patterning, patterns of ocular dominance, and connection between nerve cell and muscle, and retinotopic maps. Carreira-Perpinan, M. A. & Goodhill, G. J. (2002) deal with the optimization of the computerized models of the visual cortex. With the enormous number of models that have been created, tools have been developed for dissemination of the information, as well as platforms to develop models. Several generalized tools, such as GENESIS, NEURON, XPP, and NEOSIM are available and are discussed by Hucka, M. (2002). Nervous system network models Network of human nervous system comprises nodes