Liver function tests protein synthesized in the liver. It is the carrier of the copper ion. Its levels is increased in infections, rheumatoid arthritis, pregnancy, non Wilson liver disease and obstructive jaundice. In Wilson disease, the ceruloplasmin level is depressed which lead to copper accumulation in body tissues. AFP is significantly expressed in foetal liver. However, the mechanism that led to the suppression of AFP synthesis in adults is not fully known. Exposure of the liver to cancer-causing agents and arrest of liver maturation in childhood can lead to the rise in AFP. AFP can reach until 400–500 μg/L in hepatocellular carcinoma. AFP
Brain damage in the thalamus or hypothalamus, which controls the nervous and endocrine system. Due to the bleeding, brain damage occurs causing problems with vision, coordination and balance. Korsakoff psychosis typically follow after the symptoms of Wernicke’s decrease and result from chronic brain damage. Korsakoff psychosis affect memory. Wernicke-Korsakoff Syndrome is typically caused by chronic alcohol abuse or by conditions that affect nutritional absorption, including colon cancer, eating disorders and gastric bypass. Brain lesions are sometimes intentionally inflicted during neurosurgery, such as the carefully placed brain lesion used to treat epilepsy and other brain disorders. These lesions are induced by excision or