Liver function tests protein synthesized in the liver. It is the carrier of the copper ion. Its levels is increased in infections, rheumatoid arthritis, pregnancy, non Wilson liver disease and obstructive jaundice. In Wilson disease, the ceruloplasmin level is depressed which lead to copper accumulation in body tissues. AFP is significantly expressed in foetal liver. However, the mechanism that led to the suppression of AFP synthesis in adults is not fully known. Exposure of the liver to cancer-causing agents and arrest of liver maturation in childhood can lead to the rise in AFP. AFP can reach until 400–500 μg/L in hepatocellular carcinoma. AFP
Right hemisphere brain damage shifted to include right hemisphere damage (Brookshire, 2007). It is now well established that language and cognition can be seriously impaired by unilateral right hemisphere brain damage. Specific cognitive tests can help diagnose the existence of right hemisphere brain damage and differentiate symptoms from those of left hemisphere damage. Unlike the aphasias, caused by left hemisphere damage and generally resulting in focused language deficits, right hemisphere brain damage can result in a variety of diffuse deficits which complicate formal testing of this disorder (Brookshire, 2007). These formal tests assess areas such as understanding humor, metaphors, sarcasm, facial expression, and prosody.