History of slavery in Louisiana History of slavery in Louisiana Following Robert Cavelier de La Salle establishing the French claim to the territory and the introduction of the name "Louisiana", the first settlements in the southernmost portion of Louisiana (New France) were developed at present-day Biloxi (1699), Mobile (1702), Natchitoches (1714), and New Orleans (1718). Slavery was then established by European colonists. The institution was maintained by the Spanish (1763–1800) when the area was part of New Spain, by the French when they briefly reacquired the colony (1800-03), and by the United States following the Louisiana Purchase of 1803. Due to its complex history, Louisiana
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