Smallpox vaccine Smallpox vaccine Smallpox vaccine, the first successful vaccine to be developed, was introduced by Edward Jenner in 1796. He followed up his observation that milkmaids who had previously caught cowpox did not later catch smallpox by showing that inoculated cowpox protected against inoculated smallpox. Dryvax is a freeze-dried calf lymph smallpox vaccine. It is the world's oldest smallpox vaccine, created in the late 19th century by American Home Products, a predecessor of Wyeth. By the 1940s, Wyeth was the leading US manufacturer of the vaccine and the only manufacturer by the 1960s. After world health authorities declared smallpox had been
Mozart and smallpox both children's illness to contend with, the Mozarts spent a total of four months away from Vienna. They eventually returned there and were received in the Imperial court on 19 January, 1768. The Empress, who had by now lost three children to smallpox, conversed with Frau Mozart about the disease. The remainder of the trip was not especially successful. Leopold apparently misinterpreted a chance remark of the Emperor as a firm invitation for Wolfgang to compose an opera; this resulted in Wolfgang writing "La finta semplice". However, the opera went unperformed in Vienna; the singers and musicians did not like