Calcium-induced calcium release Calcium-induced calcium release Calcium-induced calcium release (CICR) describes a biological process whereby calcium is able to activate calcium release from intracellular Ca stores (e.g., endoplasmic reticulum or sarcoplasmic reticulum). Although CICR was first proposed for skeletal muscle in the 1970s, it is now known that CICR is unlikely to be its primary mechanism for activating SR calcium release. Instead, CICR is thought to be crucial for excitation-contraction coupling in cardiac muscle and it is now obvious that CICR is a widely occurring cellular signaling process present even in many non-muscle cells, e.g. in the insulin-secreting pancreatic beta cells and many
Calcium lactate 75% relative humidity. Calcium lactate can be prepared by the reaction of lactic acid with calcium carbonate or calcium hydroxide. Since the 19th century, the salt has been obtained industrially by fermentation of carbohydrates in the presence of calcium mineral sources such as calcium carbonate or calcium hydroxide. Fermentation may produce either D or L lactate, or a racemic mixture of both, depending on the type of organism used. Calcium lactate has several uses in human and veterinary medicine. Calcium lactate is used in medicine as an antacid. Calcium lactate is also used to treat hypocalcaemia (calcium deficiencies). It can