Malaria with other antimalarials (known as artemisinin-combination therapy, or ACT), which decreases resistance to any single drug component. These additional antimalarials include: amodiaquine, lumefantrine, mefloquine or sulfadoxine/pyrimethamine. Another recommended combination is dihydroartemisinin and piperaquine. ACT is about 90% effective when used to treat uncomplicated malaria. To treat malaria during pregnancy, the WHO recommends the use of quinine plus clindamycin early in the pregnancy (1st trimester), and ACT in later stages (2nd and 3rd trimesters). In the 2000s (decade), malaria with partial resistance to artemisins emerged in Southeast Asia. Infection with "P. vivax", "P. ovale" or "P. malariae" usually do not require
But what about the noise of crumpling paper which he used to do in order to paint the series of "Papiers froissés" or tearing up paper to make "Papiers déchirés?" Arp was stimulated by water (sea, lake, and flowing waters like rivers), forests made of wood, metal and glass, "O" is the sound of pouring or bubbling in water and crumpling and tearing paper, and "(" and ")" are also these sounds but cut in half, that is, sounded twice and always for the same length of time. Given the indeterminate nature of this composition, each performance tends to feature distinct traits, and the main performer is often credited for "realizing" the piece. The following is a partial list of recordings of this piece: But what about the noise of crumpling paper which he used to do in order to paint the series