Gin and tonic of water, sugar, lime and gin to the quinine in order to make the drink more palatable, thus gin and tonic was born. Soldiers in India were already given a gin ration, and the sweet concoction made sense. Since it is no longer used as an antimalarial, tonic water today contains much less quinine, is usually sweetened, and is consequently much less bitter. Gin and tonic is a popular cocktail during the summer. A 2004 study found that after 12 hours, "considerable quantities (500 to 1,000 ml) of tonic water may, for a short period of time, lead to quinine
Clausena anisata half maximal effective concentration (EC50) value was 74 μg/mL. The authors concluded that these results encourage further investigation of the use of this plant as complementary treatment options for ascariasis. This species is used in treating an uncommonly wide range of ailments and conditions. Decoctions of the leaves or roots are taken for gastro-intestinal disorders, fever, pneumonia, headache, hypotension, sore throat and sinusitis, venereal diseases, as an aphrodisiac and anthelmintic, as a tonic for pregnant women, and as a tonic for infants to prevent rickets and to control convulsions. Root decoctions and infusions are also taken for whooping cough, malaria,