Variolation shortly after variolation began to outweigh the benefits of the procedure. From the 1760s, a number of individuals, including John Fewster, Peter Plett, Benjamin Jesty, and particularly Edward Jenner, were interested in the use of material from cowpox, an animal infection, to protect against smallpox. In 1796, Jenner vaccinated James Phipps, did more vaccinations in 1798, and was the first to publish evidence that cowpox protected against smallpox, was safer than variolation, and that his vaccine could be maintained by arm-to-arm transfer. The use of variolation soon began to decline as the smallpox vaccine became widely used and its benefits
Who Made Who Stephen King movie "Maximum Overdrive", where the theme was around machines that came alive and begin killing people. The lyrics follow the idea of the gadgets and devices created by mankind coming to rule over human beings instead of the other way around; the irony where humans become subservient to the technology they created. The song "Who Made Who" became the band's most successful single in years, reaching #16 in the UK and #33 in the US. It was also voted second best track of 1986 by the readers of "Hit Parader" magazine. Following this, a re-issue of "You Shook