Hepatitis In hemochromatosis, excess amounts of iron accumulate in multiple body sites, including the liver, which can lead to cirrhosis. In Wilson's disease, excess amounts of copper accumulate in the liver and brain, causing cirrhosis and dementia. When the liver is involved, alpha-1-antitrypsin deficiency and Wilson's disease tend to present as hepatitis in the neonatal period or in childhood. Hemochromatosis typically presents in adulthood, with the onset of clinical disease usually after age 50. Ischemic hepatitis (also known as shock liver) results from reduced blood flow to the liver as in shock, heart failure, or vascular insufficiency. The condition is most
Lead and Copper Rule home, the water supplier may leave the sample bottles and sampling instructions with the consumer. EPA was investigated by the Government Accountability Office (GAO) in 2003 following the discovery of higher-than-acceptable copper and lead levels in tap water in the District of Columbia. The GAO reported that EPA had not been collecting copper and lead levels from the states, despite claims that the levels of copper and lead have decreased; data for 72 percent of water systems were missing. EPA may have been lacking data because more resources were being dedicated to lead regulation than lead reporting. Lead and Copper