Smallpox 1718. In 1721, Cotton Mather and colleagues provoked controversy in Boston by inoculating hundreds. In 1796, Edward Jenner, a doctor in Berkeley, Gloucestershire, rural England, discovered that immunity to smallpox could be produced by inoculating a person with material from a cowpox lesion. Cowpox is a poxvirus in the same family as variola. Jenner called the material used for inoculation vaccine, from the root word "vacca", which is Latin for cow. The procedure was much safer than variolation, and did not involve a risk of smallpox transmission. Vaccination to prevent smallpox was soon practiced all over the world. During the
Smallpox demon parts of India, China, Africa and Latin America, sacrifices were made to appease the gods of smallpox. In medieval Europe, prayer and pious living were recommended as one way to guard against sickness. Many Japanese textbooks on dermatology stated that red light was able to weaken the symptoms of smallpox. This was common in China, India, Turkey and Georgia. In western Africa, the Yoruba god of smallpox, Sopona, was associated with the color red. The red treatment was given scientific authority by Finsen, who claimed that the treatment of smallpox patients with red light reduced the severity of scarring, and