Tonic water and other tropical posts mixed the powder with soda and sugar, and tonic water was created. The first commercial tonic water was produced in 1858. The mixed drink gin and tonic also originated in British colonial India, when the British mixed their medicinal quinine tonic with gin. Since 2010, at least four tonic syrups have been available in the US. Consumers add carbonated water to the syrup to make tonic water, allowing drinkers to adjust the flavor intensity. Medicinal tonic water originally contained only carbonated water and a large amount of quinine. However, most tonic water today contains less quinine
Human genetic resistance to malaria ways that have a detrimental effect on the health or longevity of the individual. However, if the net effect of protection against malaria outweighs the other detrimental effects, the protective mutation will tend to be retained and propagated from generation to generation. These alterations which protect against malarial infections but impair red blood cells are generally considered blood disorders, since they tend to have overt and detrimental effects. Their protective function has only in recent times, been discovered and acknowledged. Some of these disorders are known by fanciful and cryptic names like sickle-cell anemia, thalassaemia, glucose-6-phosphate dehydrogenase deficiency, ovalocytosis, elliptocytosis