Tonic water and is used mostly for its flavor. As a result of the lower quinine content, it is less bitter, and is also usually sweetened, often with high-fructose corn syrup or sugar. Some manufacturers also produce diet (or slimline) tonic water, which may contain artificial sweeteners such as aspartame. Traditional-style tonic water with little more than quinine and carbonated water is less common but may be preferred by those who desire the bitter flavor. In the United States, the US Food and Drug Administration (FDA) limits the quinine content in tonic water to 83 ppm (83 mg per liter if calculated
Malaria in pregnant women and infants, and in preschool children where transmission is seasonal. There are a number of medications that can help prevent or interrupt malaria in travelers to places where infection is common. Many of these medications are also used in treatment. In places where "Plasmodium" is resistant to one or more medications, three medications—mefloquine, doxycycline , or the combination of atovaquone/proguanil ("Malarone")—are frequently used for prevention. Doxycycline and the atovaquone/proguanil are better tolerated while mefloquine is taken once a week. Areas of the world with chloroquine sensitive malaria are uncommon. The protective effect does not begin immediately, and