Adrenaline of epinephrine can be seen in autonomic neuropathy or following adrenalectomy. Failure of the adrenal cortex, as with Addisons disease, can suppress epinephrine secretion as the activity of the synthesing enzyme, phenylethanolamine-"N"-methyltransferase, depends on the high concentration of cortisol that drains from the cortex to the medulla. In 1901, Jokichi Takamine patented a purified extract from the adrenal glands, and called it "adrenalin" (from the Latin for "on top of the kidneys" ("ad" and "renal"), which was trademarked by Parke, Davis & Co in the US. The British Approved Name and European Pharmacopoeia term for this drug is hence "adrenaline".
Cortex System "Smallville does something rare in a licensed game: not only does it deliver an experience that captures the feel of the original, but also comes up with a set of mechanics that create an entirely new dynamic for roleplaying." Cortex System The Cortex System is a generic RPG system based on the "Sovereign Stone System", and was developed by Margaret Weis Productions, Ltd for the Serenity Role Playing Game. It was subsequently used for their licensed "Battlestar Galactica" and Supernatural RPGs, and brought out as a stand-alone system in the "Cortex System Role Playing Game" book (also called the "Cortex