History of malaria fever with quinine, the effects of both syphilis and malaria could be minimized. While about 15% of patients died from malaria, this was preferable to the almost-certain death from syphilis. Therapeutic malaria opened up a wide field of chemotherapeutic research and was practised until 1950. Wagner-Jauregg was awarded the 1927 Nobel Prize in Physiology or Medicine for his discovery of the therapeutic value of malaria inoculation in the treatment of dementia paralytica. Henry Heimlich advocated malariotherapy as a treatment for AIDS, and some studies of malariotherapy for HIV infection have been performed in China. The United States Centers for Disease
The Iron Tonic 19th-century-engraving style, the work comprises 14 panels of illustration and rhyming text in iambic pentameter. It tells the story of an eerie, melancholy manor whose inhabitants are either old or unwell. Wim Tigges described the book as "a compilation of hardly related couplets," in which nonsense objects "are seen to be falling unaccountably out of the sky." Tigges notes it uses a device commonly used in Gorey's writing, "the unexplained recurrence of an irrelevant object". The Iron Tonic The Iron Tonic: Or, A Winter Afternoon in Lonely Valley is a Surrealist country-house mystery—that is, a series of clues that don't