Science and invention in Birmingham 1054 Mk XVIs) had been built. CBAF became the largest and most successful plant of its type during the 1939–45 conflict. As the largest Spitfire factory in the UK, by producing up to 320 aircraft per month, it built over half of the approximately 20,000 aircraft of this type. 1944: Anthony Ernest Pratt takes out his first patent for a board game named 'Murder', this is later to become the world-renowned murder mystery game 'Cluedo'. 1946: Chance Brothers produce the first all-glass syringe with interchangeable barrel and plunger, thereby allowing mass sterilisation of components without the need for matching them.
Mystery fiction before the 1800s was due in part to the lack of true police forces. Before the Industrial Revolution, many of the towns would have constables and a night watchman at best. Naturally, the constable would be aware of every individual in the town, and crimes were either solved quickly or left unsolved entirely. As people began to crowd into cities, police forces became institutionalized, and the need for detectives was realized – thus the mystery novel arose. An early work of modern mystery fiction, "Das Fräulein von Scuderi" by E. T. A. Hoffmann (1819), was an influence on "The Murders