Cheers (season 1) People", intended to satirize "the lifestyle of old decadent old-money WASPs," but, to meet producers' demands, they rewrote the lyrics to be about "likeable losers" in a Boston bar. The show's producers rejected this song, as well as later songs that Portnoy and Angelo wrote. When Portnoy and Hart Angelo heard that NBC had commissioned thirteen episodes, they created "Where Everybody Knows Your Name", and rewrote the lyrics. "Cheers" was first broadcast at 9:00pm (Eastern) / 8:00pm (Central) on Thursday during fall 1982, which later became NBC's Must See TV, which followed the hour-long musical series "Fame" and preceded another
Daniel A. Portnoy Pennsylvania, where he collaborated with Dr. Lewis Tilney in the Biology Department and made the observation that "L. monocytogenes" spreads from one cell to another by exploiting a host cell system of actin polymerization. His lab also defined the role of the listerial hemolysin in mediating dissolution of phagosomes. In collaboration with Dr. Philip Youngman, he showed that expression of the "L. monocytogenes" hemolysin by "Bacillus subtilis" led to its growth inside of host cells. Dr. Portnoy collaborated with Dr. Yvonne Paterson, who also arrived at Penn in 1988, on the use of "L. monocytogenes" as a recombinant vector-based vaccine