Calcium-induced calcium release Calcium-induced calcium release Calcium-induced calcium release (CICR) describes a biological process whereby calcium is able to activate calcium release from intracellular Ca stores (e.g., endoplasmic reticulum or sarcoplasmic reticulum). Although CICR was first proposed for skeletal muscle in the 1970s, it is now known that CICR is unlikely to be its primary mechanism for activating SR calcium release. Instead, CICR is thought to be crucial for excitation-contraction coupling in cardiac muscle and it is now obvious that CICR is a widely occurring cellular signaling process present even in many non-muscle cells, e.g. in the insulin-secreting pancreatic beta cells and many
What Bird is That? of "What Bird is That?" It was published in 1984 and incorporated all of Cayley’s paintings created over many years for his vision of releasing a “big bird book” and included a revised taxonomy. In the 53 years since its first edition, more than a hundred new bird species had been identified in Australia. Scientific names had been changed and groups of birds had been reordered. Lindsey brought "What Bird is That?" up-to-date with the latest birding conventions of the time, as well as contributing a valuable supplementary list of birds and a scholarly catalogue of Cayley’s paintings. The "Signature