Adrenaline of epinephrine can be seen in autonomic neuropathy or following adrenalectomy. Failure of the adrenal cortex, as with Addisons disease, can suppress epinephrine secretion as the activity of the synthesing enzyme, phenylethanolamine-"N"-methyltransferase, depends on the high concentration of cortisol that drains from the cortex to the medulla. In 1901, Jokichi Takamine patented a purified extract from the adrenal glands, and called it "adrenalin" (from the Latin for "on top of the kidneys" ("ad" and "renal"), which was trademarked by Parke, Davis & Co in the US. The British Approved Name and European Pharmacopoeia term for this drug is hence "adrenaline".
Cephalic phase gastrin circulation. It will also stimulate Chief cells to release Pepsinogen. Thinking of food (i.e. smell, sight) – Stimulates cerebral cortex – Sends messages to hypothalamus – to the medulla oblongata – to parasympathetic nervous system by the vagus nerve – to stomach (Gastric Glands in walls of fundus and body of stomach) – to secrete gastric juice. a. Food enters stomach – stomach stretches and activates stretch Receptors – sends message to the medulla oblongata (vagus nerve) and then back – to stomach by the vagus nerve — Result: parietal cell secrete gastric juice. b. Chemical Stimuli (i.e. partially