History of malaria millennium BCE in Greece and China. For thousands of years, traditional herbal remedies have been used to treat malaria. The first effective treatment for malaria came from the bark of cinchona tree, which contains quinine. After the link to mosquitos and their parasites were identified in the early twentieth century, mosquito control measures such as widespread use of the insecticide DDT, swamp drainage, covering or oiling the surface of open water sources, indoor residual spraying and use of insecticide treated nets was initiated. Prophylactic quinine was prescribed in malaria endemic areas, and new therapeutic drugs, including chloroquine and artemisinins, were
Malaria vaccine Navy were immunized against Plasmodium falciparum by the bites of 1001 to 2927 mosquitos that had been irradiated with 15,000 rads of gamma rays from a Co-60 or Cs-137 source. This level of radiation being sufficient to attenuate the malaria parasites so that while they could still enter hepatic cells, they could not develop into schizonts or infect red blood cells. Over a span of 42 weeks, 24 of 26 tests on the volunteers showed that they were protected from malaria infection. Malaria vaccine Malaria vaccine is a vaccine that is used to prevent malaria. The only approved vaccine as