Cheers decadent old-money WASPs," but, to meet producers' demands, they rewrote the lyrics to be about "likeable losers" in a Boston bar. The show's producers rejected this song, as well. After they read the script of the series pilot, they created another song "Another Day". When Portnoy and Hart Angelo heard that NBC had commissioned thirteen episodes, they created an official theme song "Where Everybody Knows Your Name" and rewrote the lyrics. On syndicated airings of "Cheers", the theme song was shortened to make room for commercials. "Cheers" was critically acclaimed in its first season, though it landed a disappointing 74th
Daniel A. Portnoy secreted by "L. monocytogenes" through multidrug resistance efflux transporters. Dr. Portnoy and Dr. Russell Vance identified that STING was the host receptor of cyclic-di-nucleotides (CDNs) that leads to the production of type I interferon and other co-regulated genes. Modified CDNs are now being evaluated for clinical application as adjuvants and for cancer immunotherapy. Dr. Portnoy has been awarded a number of honors over the course of his career including the Eli Lilly and Company Research Award in Microbiology & Immunology, NIH Merit Award, Fellow of the American Academy of Microbiology, Senior Scholar Award in Global Infectious Diseases from the Ellison