Low kick sciatic nerve, which is the longest and widest nerve in the human body, beginning in the lower back and running through the buttocks all the way to the lower limb, is a frequent target for low kicks. The most common defense against a low kick is known as "checking", where the leg is bent and brought up to protect the thigh. This causes the kicker to slam their shin into the defending fighters' shin or knee, causing pain and damage to the offender. In some instances, a well executed check of a low kick can break the leg of the
Traditional Chinese medicines derived from the human body were successfully making quasi-empirical preparations of active substances with androgens and estrogens, a technique that modern biochemists did not develop until the early 20th century. The physician William C. Cooper and the sinologist Nathan Sivin (1973) chose what the Chinese call "rényào" 人藥 "human drugs" as a pilot experiment sample for pharmacologically analyzing the efficacy of drugs used in TCM. In contrast to many traditional Chinese plant, animal, and mineral pharmaceuticals with uncertain active constituents, the chemical composition of the human body and parts is well known, and "their therapeutic effectiveness, or lack of it, can be objectively, if approximately,