Calcium-induced calcium release of CICR across the cell causes the significant increase in cytosolic Ca that is important in activating muscle contraction. Calcium-induced calcium release Calcium-induced calcium release (CICR) describes a biological process whereby calcium is able to activate calcium release from intracellular Ca stores (e.g., endoplasmic reticulum or sarcoplasmic reticulum). Although CICR was first proposed for skeletal muscle in the 1970s, it is now known that CICR is unlikely to be its primary mechanism for activating SR calcium release. Instead, CICR is thought to be crucial for excitation-contraction coupling in cardiac muscle and it is now obvious that CICR is a widely
European Calcium Society Heizmann has sponsored the publication of significant articles in the scientific journal Biochimica et Biophysica Acta. A newsletter is also produced twice a year (May and November). In 2007, ECS launched its first workshop, in Ariège (France). The second took place in June 2009 in Smolenice (Slovakia). European Calcium Society The European Calcium Society is a non-profit society that aims to develop relationships between different generations of scientists in Europe working in the field of calcium signaling and the proteins involved in the Calcium Toolkit. The First European Symposium took place in 1989 and covered calcium binding proteins in normal