Opioid selling Indian opium which was smuggled into China in defiance of Chinese government bans. This led to the First (1839–1842) and Second Opium Wars (1856–1860) between China and Britain. In the 19th century, two major scientific advances were made that had far-reaching effects. Around 1804, German pharmacist Friedrich Sertürner isolated morphine from opium. He described its crystallization, structure, and pharmacological properties in a well-received paper in 1817. Morphine was the first alkaloid to be isolated from any medicinal plant, the beginning of modern scientific drug discovery. The second advance, nearly fifty years later, was the refinement of the hypodermic needle
History of Chinese immigration to the United Kingdom at that time, the East India Company, expanded, China became a hugely important and profitable market. In the mid-18th century, imported Chinese products became fashionable, particularly porcelain. Tea dominated the Anglo-Chinese trade as it quickly became an English habit and its consumption grew in Britain, but there was nothing comparable that the Chinese wished to buy from the British. The Company began to export opium from India to China, selling the drug to raise the money to buy shipments of tea. This was against the law and angered China's authorities. In 1839, war broke out between Britain and China over