Opioid selling Indian opium which was smuggled into China in defiance of Chinese government bans. This led to the First (1839–1842) and Second Opium Wars (1856–1860) between China and Britain. In the 19th century, two major scientific advances were made that had far-reaching effects. Around 1804, German pharmacist Friedrich Sertürner isolated morphine from opium. He described its crystallization, structure, and pharmacological properties in a well-received paper in 1817. Morphine was the first alkaloid to be isolated from any medicinal plant, the beginning of modern scientific drug discovery. The second advance, nearly fifty years later, was the refinement of the hypodermic needle
Campaign to Suppress Bandits in Northeast China war efforts, which ultimately led to their final victory. Communists, like their nationalist counterparts, also made a grave miscalculation, but in comparison to the nationalists, the communists were very quick in correcting their miscalculation and avoided disasters nationalists had suffered. The communist miscalculation was only made in the initial stage when they first ventured into Northeast China after World War II: during the start of their Campaign to Establish Communist Base in Northeast China, communists were eager to expand their force in region, but most of the communist force sent to Northeast China did not reach their final destination, especially