Ernest Lawrence a scrap of a paper napkin. While sitting in the library one evening in 1929, Lawrence glanced over a journal article by Rolf Widerøe, and was intrigued by one of the diagrams. This depicted a device that produced high-energy particles by means of a succession of small "pushes". The device depicted was laid out in a straight line using increasingly longer electrodes. At the time, physicists were beginning to explore the atomic nucleus. In 1919, the New Zealand physicist Ernest Rutherford had fired alpha particles into nitrogen and had succeeded in knocking protons out of some of the nuclei. But
Janus particles settling, thus enabling these nanoparticles as biocompatible multifunctional probes for bioimaging. Next, by labeling their surfaces and selectively binding them on the membrane of live-tagged Raji and HeLa cells, this demonstrated the nanoparticles as biomarkers and their detection under dark-field illumination was achieved. These new hybrid Janus nanoparticles overcame the individual limitations of FeO (poor particle stability in suspension) and of Ag (toxicity) nanoparticles, while retaining the desired magnetic properties of FeO and the plasmonic optical properties of Ag. The potential application of Janus particles was first demonstrated by Nisisako "et al.", who made use of the electrical anisotropy of