Adrenaline of epinephrine can be seen in autonomic neuropathy or following adrenalectomy. Failure of the adrenal cortex, as with Addisons disease, can suppress epinephrine secretion as the activity of the synthesing enzyme, phenylethanolamine-"N"-methyltransferase, depends on the high concentration of cortisol that drains from the cortex to the medulla. In 1901, Jokichi Takamine patented a purified extract from the adrenal glands, and called it "adrenalin" (from the Latin for "on top of the kidneys" ("ad" and "renal"), which was trademarked by Parke, Davis & Co in the US. The British Approved Name and European Pharmacopoeia term for this drug is hence "adrenaline".
Cortex System Cortex System The Cortex System is a generic RPG system based on the "Sovereign Stone System", and was developed by Margaret Weis Productions, Ltd for the Serenity Role Playing Game. It was subsequently used for their licensed "Battlestar Galactica" and Supernatural RPGs, and brought out as a stand-alone system in the "Cortex System Role Playing Game" book (also called the "Cortex Classic System Role Playing Game"). Serenity, using the Cortex System, was the 2005 Origins Award Gamer's Choice Role Playing Game of the Year. Note that despite the similar name, the Cortex System is not the Cortex Plus system, also