Malaria with other antimalarials (known as artemisinin-combination therapy, or ACT), which decreases resistance to any single drug component. These additional antimalarials include: amodiaquine, lumefantrine, mefloquine or sulfadoxine/pyrimethamine. Another recommended combination is dihydroartemisinin and piperaquine. ACT is about 90% effective when used to treat uncomplicated malaria. To treat malaria during pregnancy, the WHO recommends the use of quinine plus clindamycin early in the pregnancy (1st trimester), and ACT in later stages (2nd and 3rd trimesters). In the 2000s (decade), malaria with partial resistance to artemisins emerged in Southeast Asia. Infection with "P. vivax", "P. ovale" or "P. malariae" usually do not require
Body of water example, most reservoirs are created by engineering dams, but some natural lakes are used as reservoirs. Similarly, most harbors are naturally occurring bays, but some harbors have been created through construction. Bodies of water that are navigable are known as waterways. Some bodies of water collect and move water, such as rivers and streams, and others primarily hold water, such as lakes and oceans. The term "body of water" can also refer to a reservoir of water held by a plant, technically known as a phytotelma. Bodies of water are affected by gravity which is what creates the tidal effects