Ernest Lawrence a scrap of a paper napkin. While sitting in the library one evening in 1929, Lawrence glanced over a journal article by Rolf Widerøe, and was intrigued by one of the diagrams. This depicted a device that produced high-energy particles by means of a succession of small "pushes". The device depicted was laid out in a straight line using increasingly longer electrodes. At the time, physicists were beginning to explore the atomic nucleus. In 1919, the New Zealand physicist Ernest Rutherford had fired alpha particles into nitrogen and had succeeded in knocking protons out of some of the nuclei. But
Hepatocyte nuclear factor 4 alpha the HNF4A gene are associated with a form of diabetes called maturity onset diabetes of the young (MODY). Increased amplification of hepatocyte nuclear factor 4 alpha has been observed in colorectal cancer. Hepatocyte nuclear factor 4 alpha has been shown to interact with: Hepatocyte nuclear factor 4 alpha Hepatocyte nuclear factor 4 alpha (HNF4A) also known as NR2A1 (nuclear receptor subfamily 2, group A, member 1) is a nuclear receptor that in humans is encoded by the "HNF4A" gene. HNF-4α is a nuclear transcription factor that binds DNA as a homodimer. The encoded protein controls the expression of several genes,