Smallpox one-third of the cases resulted in blindness. These deaths included those of four reigning monarchs and a queen consort. In the 20th century smallpox killed 200-300 million people. Edward Jenner discovered in 1798 that vaccination could prevent smallpox. In 1967, the WHO intensified efforts to eliminate the disease. Smallpox is one of two infectious diseases to have been eradicated, the other being rinderpest in 2011. The term "smallpox" was first used in Britain in the 15th century to distinguish the disease from syphilis, which was then known as the "great pox". Other historical names for the disease include pox, speckled
Genocides in history smallpox vaccinations, which had been provided to other tribes in other areas. Some historians disagree that genocide, defined as a crime of intent, should be used to describe the colonization experience. Stafford Poole, a research historian, wrote: "There are other terms to describe what happened in the Western Hemisphere, but genocide is not one of them. It is a good propaganda term in an age where slogans and shouting have replaced reflection and learning, but to use it in this context is to cheapen both the word itself and the appalling experiences of the Jews and Armenians, to mention but