Tonic water and is used mostly for its flavor. As a result of the lower quinine content, it is less bitter, and is also usually sweetened, often with high-fructose corn syrup or sugar. Some manufacturers also produce diet (or slimline) tonic water, which may contain artificial sweeteners such as aspartame. Traditional-style tonic water with little more than quinine and carbonated water is less common but may be preferred by those who desire the bitter flavor. In the United States, the US Food and Drug Administration (FDA) limits the quinine content in tonic water to 83 ppm (83 mg per liter if calculated
History of malaria bites, is unknown. The presence of malaria in Egypt from circa 800 BCE onwards has been confirmed using DNA-based methods. Malaria became widely recognized in ancient Greece by the 4th century BCE, and is implicated in the decline of many city-state populations. The term "μίασμα" (Greek for miasma): "stain, pollution", was coined by Hippocrates of Kos who used it to describe dangerous fumes from the ground that are transported by winds and can cause serious illnesses. Hippocrates (460–370 BCE), the "father of medicine", related the presence of intermittent fevers with climatic and environmental conditions and classified the fever according to