Lead and Copper Rule especially for young children and pregnant women." It also explained that the rule has reduced copper exposure "that can cause stomach and intestinal distress, liver or kidney damage, and complications of Wilson’s disease in genetically predisposed people." Although lead is a known poison, the mechanical and chemical characteristics of the metal continue to keep lead as an important component in many products. In water supply, lead's durability and workability selected it for use as water pipes. Lead alloys (bronze, brass) are used for plumbing fittings. Lead solders were preferred in plumbing. While lead pipes were replaced by other materials, such
Brain-body interaction shown that brain activity in different brain areas are coupled and form brain networks that can be studied using graph theory. Brain-body interactions can be studied using a similar approach by estimating functional connectivity between brain activity and peripheral electrophysiology, for example between brain activity and ECG, EGG or EMG activity. Synchrony between slow pulse fluctuations (related to sympathetic activity) and brain fMRI signal has revealed a network of sensory brain regions that appear to be relevant for characterizing human personality and emotions. These analyses can be extended to investigate interactions between multiple organ systems that together form a brain-body