Alpha particle types: eventually named alpha, beta, and gamma by Rutherford, based on penetration of objects and deflection by a magnetic field. Alpha rays were defined by Rutherford as those having the lowest penetration of ordinary objects. Rutherford's work also included measurements of the ratio of an alpha particle's mass to its charge, which led him to the hypothesis that alpha particles were doubly charged helium ions (later shown to be bare helium nuclei). In 1907, Ernest Rutherford and Thomas Royds finally proved that alpha particles were indeed helium ions. To do this they allowed alpha particles to penetrate a very thin
Karyopherin alpha 2 Karyopherin alpha 2 Importin subunit alpha-2 is a protein that in humans is encoded by the "KPNA2" gene. The import of proteins into the nucleus is a process that involves at least 2 steps. The first is an energy-independent docking of the protein to the nuclear envelope and the second is an energy-dependent translocation through the nuclear pore complex. Imported proteins require a nuclear localization sequence (NLS) which generally consists of a short region of or 2 such regions spaced about 10 amino acids apart. Proteins involved in the first step of nuclear import are members of the alpha importin