Freckle regular use of sunblock can inhibit their development. Liver spots (also known as sun spots and lentigines) look like large freckles, but they form after years of exposure to the sun. Liver spots are more common in older people. Freckle Freckles are clusters of concentrated melaninized cells which are most easily visible on people with a fair complexion. Freckles do not have an increased number of the melanin-producing cells, or melanocytes, but instead have melanocytes that overproduce melanin granules (melanosomes) changing the coloration of the outer skin cells (keratinocytes). As such, freckles are different from lentigines and moles, which are
Freckles and His Friends Newspaper Enterprise Association, "Freckles and His Friends" had a long run through much of the 20th Century. In May 1915, 23-year-old Merrill Blosser began working for the Chicago syndicate Newspaper Enterprise Association, initially drawing cartoons based on news events. That summer he began drawing five comics features. One of these, titled "Freckles", began as a one-column daily gag panel on August 16, 1915. that expanded into a full comic strip and was retitled "Freckles and His Friends" on September 20, 1915. One by one, Blosser dropped each of the other single-panel comics, and in July 1916, he began another strip,