Virology in order to immunize others. In 1717 Lady Mary Wortley Montagu observed the practice in Istanbul and attempted to popularize it in Britain, but encountered considerable resistance. In 1796 Edward Jenner developed a much safer method, using cowpox to successfully immunize a young boy against smallpox, and this practice was widely adopted. Vaccinations against other viral diseases followed, including the successful rabies vaccination by Louis Pasteur in 1886. The nature of viruses however was not clear to these researchers. In 1892, the Russian biologist Dmitry Ivanovsky used a Chamberland filter to try to isolate the bacteria that caused tobacco mosaic
HMS Surprise (1796) time, Le Drézénec, who had been recently promoted to "capitaine de frégate", was suffering from smallpox and was incapacitated. Consequently, her first lieutenant, Lieutenant Le Breton, commanded "Unité". Captain Thomas Fremantle in command of the frigate HMS "Inconstant" had heard there was a French frigate in Bône, and sailed to intercept her. When "Unité" arrived in the afternoon of 20 April 1796, the watch aboard "Unité" identified "Inconstant" as a neutral vessel and Le Breton did not clear the ship for action. About an hour later, "Inconstant" sailed alongside, boarded and captured "Unité" intact. About a year after capture, "Unité"