Calcium pump Calcium pump Calcium pumps are a family of ion transporters found in the cell membrane of all animal cells. They are responsible for the active transport of calcium out of the cell for the maintenance of the steep Ca electrochemical gradient across the cell membrane. Calcium pumps play a crucial role in proper cell signalling by keeping the intracellular calcium concentration roughly 10,000 times lower than the extracellular concentration. Failure to do so is one cause of muscle cramps. The plasma membrane Ca ATPase and the sodium-calcium exchanger are together the main regulators of intracellular Ca concentrations. Ca has many
The Lost Symbol as the commands of an all-powerful deity. This interpretation has been lost amid centuries of scientific skepticism and fundamentalist zealotry. The Masons have (metaphorically) buried it, believing that, when the time is right, its rediscovery will usher in a new era of human enlightenment. "The Lost Symbol" had been in development for several years; originally expected in 2006, the projected publication date was pushed back multiple times. When officially announced, the hardcopy book was on pre-order lists for months leading up to its release, being heavily ordered both in the United States and Canada. The book was published on September