Mozart and smallpox the imperial family were successful, and led to greater public acceptance for the procedure. Smallpox struck the Mozart family again in the next generation: Nannerl's eldest son Leopold and two of her stepchildren caught the disease during an outbreak in the Salzburg area in 1787. All three children survived. In 1796, the discovery of vaccination—the use of the related cowpox virus to immunize against smallpox—by Edward Jenner revolutionized the ability of medicine to deal with smallpox. Vaccination reached Vienna around 1800, when yet another local epidemic created impetus for its adoption. One of the doctors trained in the Vienna campaign,
1775–82 North American smallpox epidemic public. These measures included the refusal to allow contact between his soldiers and the viral refugees of Boston. Additionally, certain retreats of the Continental Army can be linked to Washington's wish to avoid smallpox and his intense caution when it came to his troops. Though it was practiced in many parts of the world, the technology of inoculation, or Variolation, was not known in Europe until the 1700s. It was widely publicized by Lady Mary Wortley Montagu, who inoculated her own children against smallpox, despite widespread concern and controversy. Inoculation was the practice of introducing infected materials in to the