Smallpox 1718. In 1721, Cotton Mather and colleagues provoked controversy in Boston by inoculating hundreds. In 1796, Edward Jenner, a doctor in Berkeley, Gloucestershire, rural England, discovered that immunity to smallpox could be produced by inoculating a person with material from a cowpox lesion. Cowpox is a poxvirus in the same family as variola. Jenner called the material used for inoculation vaccine, from the root word "vacca", which is Latin for cow. The procedure was much safer than variolation, and did not involve a risk of smallpox transmission. Vaccination to prevent smallpox was soon practiced all over the world. During the
1974 smallpox epidemic in India 1974 smallpox epidemic in India The 1974 smallpox epidemic of India was one of the worst smallpox epidemics of 20th century. Over 15,000 people contracted and died from smallpox between January and May 1974. Most of the deaths occurred in the Indian states of Bihar, Orissa and West Bengal. There were thousands who survived but were disfigured or blinded. India reported 61,482 cases of smallpox to World Health Organization (WHO) in these five months. India had over 86% of the world's smallpox cases in 1974, primarily due to this epidemic. By January 1975, an operation was started aimed at containing