Malaria with other antimalarials (known as artemisinin-combination therapy, or ACT), which decreases resistance to any single drug component. These additional antimalarials include: amodiaquine, lumefantrine, mefloquine or sulfadoxine/pyrimethamine. Another recommended combination is dihydroartemisinin and piperaquine. ACT is about 90% effective when used to treat uncomplicated malaria. To treat malaria during pregnancy, the WHO recommends the use of quinine plus clindamycin early in the pregnancy (1st trimester), and ACT in later stages (2nd and 3rd trimesters). In the 2000s (decade), malaria with partial resistance to artemisins emerged in Southeast Asia. Infection with "P. vivax", "P. ovale" or "P. malariae" usually do not require
Disposal of a corpse with intent to obstruct or prevent a coroner's inquest of a dead body or disposing of a dead body in order to prevent the holding of an inquest over it in a case where the coroner has reasonable ground for holding an inquest. It is a separate common law offence to Prevent the lawful (and decent) burial of a body. Disposal of a corpse with intent to obstruct or prevent a coroner's inquest Disposal of a corpse with intent to obstruct or prevent a coroner's inquest is an offence under the common law of England and Wales. The offence is currently very rarely charged. As a common law offence,