Variolation shortly after variolation began to outweigh the benefits of the procedure. From the 1760s, a number of individuals, including John Fewster, Peter Plett, Benjamin Jesty, and particularly Edward Jenner, were interested in the use of material from cowpox, an animal infection, to protect against smallpox. In 1796, Jenner vaccinated James Phipps, did more vaccinations in 1798, and was the first to publish evidence that cowpox protected against smallpox, was safer than variolation, and that his vaccine could be maintained by arm-to-arm transfer. The use of variolation soon began to decline as the smallpox vaccine became widely used and its benefits
The Successful Pyrate The Successful Pyrate The Successful Pyrate is a play by Charles Johnson, first performed 1712, published 1713, dealing with the life of the pirate Henry Avery. "The Successful Pyrate" is a romanticised dramatisation of two episodes contained in a pamphlet recently published concerning the career of the pirate Henry Avery: his capture of the Mogul Aurengzeb's ship "Gang-i-sawai", allegedly carrying the Mogul's granddaughter; and a plot against him by his lieutenant De Sale and other pirates. In the play, Avery goes under the name Arviragus, and has made himself a King in Madagascar. He captures the Indian princess Zaida and