Mozart and smallpox the imperial family were successful, and led to greater public acceptance for the procedure. Smallpox struck the Mozart family again in the next generation: Nannerl's eldest son Leopold and two of her stepchildren caught the disease during an outbreak in the Salzburg area in 1787. All three children survived. In 1796, the discovery of vaccination—the use of the related cowpox virus to immunize against smallpox—by Edward Jenner revolutionized the ability of medicine to deal with smallpox. Vaccination reached Vienna around 1800, when yet another local epidemic created impetus for its adoption. One of the doctors trained in the Vienna campaign,
Early clashes in the Rhine campaign of 1796 systematically divested of old men who might have tempered the rash impulses of teenagers and young adults. It had already made itself odious, by rumor and action, throughout France. Furthermore, it was an army entirely dependent upon the countryside for its material support. After April 1796, pay was made in metallic value, but pay was still in arrears. Throughout the spring and early summer, the unpaid French army was in almost constant mutiny: in May 1796, in the border town of Zweibrücken, the 74th Demi-brigade revolted. In June, the 17th Demi-brigade was insubordinate (frequently) and in the 84th Demi-brigade, two