Liver function tests protein synthesized in the liver. It is the carrier of the copper ion. Its levels is increased in infections, rheumatoid arthritis, pregnancy, non Wilson liver disease and obstructive jaundice. In Wilson disease, the ceruloplasmin level is depressed which lead to copper accumulation in body tissues. AFP is significantly expressed in foetal liver. However, the mechanism that led to the suppression of AFP synthesis in adults is not fully known. Exposure of the liver to cancer-causing agents and arrest of liver maturation in childhood can lead to the rise in AFP. AFP can reach until 400–500 μg/L in hepatocellular carcinoma. AFP
Health effects of coal ash the particle will be inhaled into the lungs. As a result, the toxic particles can inflame the lungs causing severe damage to the body. Furthermore, coal ash dust can enter the body through the nose causing damage to the brain directly. However, regardless of particle entry, the toxicity from coal ash can cause harm to major body parts such as the brain, lungs, heart, liver, kidneys, stomach and intestines. Thus, individuals working near coal ash surface impoundments or landfills are at increased risk for many serious health problems. Lead: The exposure of lead in coal ash can cause major damage