Lead and Copper Rule especially for young children and pregnant women." It also explained that the rule has reduced copper exposure "that can cause stomach and intestinal distress, liver or kidney damage, and complications of Wilson’s disease in genetically predisposed people." Although lead is a known poison, the mechanical and chemical characteristics of the metal continue to keep lead as an important component in many products. In water supply, lead's durability and workability selected it for use as water pipes. Lead alloys (bronze, brass) are used for plumbing fittings. Lead solders were preferred in plumbing. While lead pipes were replaced by other materials, such
Free radical damage to DNA Free radical damage to DNA Free radical damage to DNA can occur as a result of exposure to ionizing radiation or to radiomimetic compounds. Damage to DNA as a result of free radical attack is called indirect DNA damage because the radicals formed can diffuse throughout the body and affect other organs. Malignant melanoma can be caused by indirect DNA damage because it is found in parts of the body not exposed to sunlight. DNA is vulnerable to radical attack because of the very labile hydrogens that can be abstracted and the prevalence of double bonds in the DNA bases