Gin and tonic Gin and tonic A gin and tonic is a highball cocktail made with gin and tonic water poured over ice. It is usually garnished with a slice or wedge of lime. The amount of gin varies according to taste. Suggested ratios of gin to tonic are between 1:1 and 1:3. In some countries (e.g., UK), gin and tonic is also marketed pre-mixed in single-serving cans. In the United States, most bars use "soda out of a gun that in no way, shape or form resembles quinine water", according to bartender Dale DeGroff. To get a real gin and tonic, DeGroff
Human genetic resistance to malaria only gene conferring innate resistance to falciparum malaria; there could be many such genes exerting more modest effects that are challenging to detect by GWA because of the low levels of linkage disequilibrium in African populations. However the same GWA association in two populations is powerful evidence that the single gene conferring strongest innate resistance to "falciparum" malaria is that encoding HbS. The fitnesses of different genotypes in an African region where there is intense malarial selection were estimated by Anthony Allison in 1954. In the Baamba population living in the Semliki Forest region in Western Uganda the sickle-cell heterozygote