History of malaria and brain which are the most constant post-mortem indications of chronic malaria infection. He related the prevalence of malaria in swampy areas to the presence of flies and recommended swamp drainage to prevent it. In the nineteenth century, the first drugs were developed to treat malaria and parasites were first identified as its source. French chemist Pierre Joseph Pelletier and French pharmacist Joseph Bienaimé Caventou separated in 1820 the alkaloids cinchonine and quinine from powdered fever tree bark, allowing for the creation of standardized doses of the active ingredients. Prior to 1820, the bark was simply dried, ground to a
What It Is to Burn the label. Reines offered the group a chance to perform and subsequently invited his sister, and co-label owner, Stefanie to the performance. The pair were impressed and signed the group. Pre-production and demos were done at DML Studios in Escondido, California in February and April 2001. They began recording "What It Is to Burn" in June at Big Fish Studios in Encinitas, California with producer Mark Trombino. They started tracking guitars in July. Strohmeyer used Fender guitars and Marshall amplifiers. Linares used ESP guitars and Mesa amplifiers. Trombino did guitar effects for the album, earning him a programming credit in