Opioid selling Indian opium which was smuggled into China in defiance of Chinese government bans. This led to the First (1839–1842) and Second Opium Wars (1856–1860) between China and Britain. In the 19th century, two major scientific advances were made that had far-reaching effects. Around 1804, German pharmacist Friedrich Sertürner isolated morphine from opium. He described its crystallization, structure, and pharmacological properties in a well-received paper in 1817. Morphine was the first alkaloid to be isolated from any medicinal plant, the beginning of modern scientific drug discovery. The second advance, nearly fifty years later, was the refinement of the hypodermic needle
Russia in the Opium Wars city), and the official right to trade opium. The Qing government rejected these demands, however this did not lead to an open conflict yet, since the main British military forces were focused on the battlefronts in Russia and Persia. After a victorious campaign in the Crimean War of 1856, Britain transferred its focus on Qing China to further expand its political influence on the empire. On October 8, 1856 they found one: Chinese authorities arrested "Arrow", a British commercial ship that was smuggling goods and selling opium. Britain demanded to free the sailors, as they believed the accusation was falsified,