Hundred Days' Reform in the First Sino-Japanese War in 1894–1895, not long after the First (1839–1842) and Second (1856–1860) Opium Wars; this blow came as a major shock to the Chinese, because Japan had been regarded as a tributary state, was much smaller than China, and was regarded as inferior. China also fought France in the Sino-French War from 1884 to 1885. Moreover, the defeat of China by Japan led to a scramble for "privileges" in China by other foreign powers, notably by the German Empire and Russia, further awakening the conservatives. Before the First Sino-Japanese War, China engaged in technological modernization only,
Protestant missions in China Chinese, treating thousands of patients. The defeat of China by Great Britain in the First Opium War resulted in the Treaty of Nanking in 1842 which opened to trade, residence by foreigners, and missionary activity five Chinese port cities: Guangzhou ("Canton"), Xiamen ("Amoy"), Fuzhou ("Foochow"), Ningbo ("Ningpo"), and Shanghai. Protestant missionary organizations established themselves in the open cities. In the Second Opium War (1856–1860) Great Britain and France defeated China. The Convention of Peking in 1860 opened up the entire country to travel by foreigners and provided for freedom of religion in China. Protestant missionary activity increased quickly after this