Opioid selling Indian opium which was smuggled into China in defiance of Chinese government bans. This led to the First (1839–1842) and Second Opium Wars (1856–1860) between China and Britain. In the 19th century, two major scientific advances were made that had far-reaching effects. Around 1804, German pharmacist Friedrich Sertürner isolated morphine from opium. He described its crystallization, structure, and pharmacological properties in a well-received paper in 1817. Morphine was the first alkaloid to be isolated from any medicinal plant, the beginning of modern scientific drug discovery. The second advance, nearly fifty years later, was the refinement of the hypodermic needle
History of opium in China no ways consider this order a dead letter and allow opium to be smuggled out! The decree had little effect. The Qing government, far away in Beijing in the north of China, was unable to halt opium smuggling in the southern provinces. A porous Chinese border and rampant local demand facilitated the trade and by the 1820s China was importing of Bengali opium annually. The opium trafficked into China was processed by the EIC at its two factories in Patna and Benares. In the 1820s, opium from Malwa in the non-British controlled part of India became available, and as prices