Smallpox one-third of the cases resulted in blindness. These deaths included those of four reigning monarchs and a queen consort. In the 20th century smallpox killed 200-300 million people. Edward Jenner discovered in 1798 that vaccination could prevent smallpox. In 1967, the WHO intensified efforts to eliminate the disease. Smallpox is one of two infectious diseases to have been eradicated, the other being rinderpest in 2011. The term "smallpox" was first used in Britain in the 15th century to distinguish the disease from syphilis, which was then known as the "great pox". Other historical names for the disease include pox, speckled
HMS Surprise (1796) time, Le Drézénec, who had been recently promoted to "capitaine de frégate", was suffering from smallpox and was incapacitated. Consequently, her first lieutenant, Lieutenant Le Breton, commanded "Unité". Captain Thomas Fremantle in command of the frigate HMS "Inconstant" had heard there was a French frigate in Bône, and sailed to intercept her. When "Unité" arrived in the afternoon of 20 April 1796, the watch aboard "Unité" identified "Inconstant" as a neutral vessel and Le Breton did not clear the ship for action. About an hour later, "Inconstant" sailed alongside, boarded and captured "Unité" intact. About a year after capture, "Unité"