Tonic water and other tropical posts mixed the powder with soda and sugar, and tonic water was created. The first commercial tonic water was produced in 1858. The mixed drink gin and tonic also originated in British colonial India, when the British mixed their medicinal quinine tonic with gin. Since 2010, at least four tonic syrups have been available in the US. Consumers add carbonated water to the syrup to make tonic water, allowing drinkers to adjust the flavor intensity. Medicinal tonic water originally contained only carbonated water and a large amount of quinine. However, most tonic water today contains less quinine
Effects of global warming of dengue fever deaths worldwide in 2004. Total attributable mortality was about 0.2% of deaths in 2004; of these, 85% were child deaths. With high confidence, authors of the IPCC AR4 Synthesis report projected that climate change would bring some benefits in temperate areas, such as fewer deaths from cold exposure, and some mixed effects such as changes in range and transmission potential of malaria in Africa. Benefits were projected to be outweighed by negative health effects of rising temperatures, especially in developing countries. With very high confidence, Confalonieri "et al." (2007) concluded that economic development was an important component