Science and invention in Birmingham 1054 Mk XVIs) had been built. CBAF became the largest and most successful plant of its type during the 1939–45 conflict. As the largest Spitfire factory in the UK, by producing up to 320 aircraft per month, it built over half of the approximately 20,000 aircraft of this type. 1944: Anthony Ernest Pratt takes out his first patent for a board game named 'Murder', this is later to become the world-renowned murder mystery game 'Cluedo'. 1946: Chance Brothers produce the first all-glass syringe with interchangeable barrel and plunger, thereby allowing mass sterilisation of components without the need for matching them.
Dune (board game) Dune (board game) Dune is a strategy board game set in Frank Herbert's "Dune" universe, published by Avalon Hill in 1979. The game was designed by Bill Eberle, Jack Kittredge and Peter Olotka. The game was originally designed with a Roman Empire theme, with the name "Tribute". Avalon Hill had acquired the license to produce a "Dune" game, and contacted Eberle, Kittredge and Olotka when their own design proved unusable. Elements suitable for the Dune universe were added to the game, particularly from their earlier game, "Cosmic Encounter". In 1984, to tie in with the Dune film, Avalon Hill published