Malaria with other antimalarials (known as artemisinin-combination therapy, or ACT), which decreases resistance to any single drug component. These additional antimalarials include: amodiaquine, lumefantrine, mefloquine or sulfadoxine/pyrimethamine. Another recommended combination is dihydroartemisinin and piperaquine. ACT is about 90% effective when used to treat uncomplicated malaria. To treat malaria during pregnancy, the WHO recommends the use of quinine plus clindamycin early in the pregnancy (1st trimester), and ACT in later stages (2nd and 3rd trimesters). In the 2000s (decade), malaria with partial resistance to artemisins emerged in Southeast Asia. Infection with "P. vivax", "P. ovale" or "P. malariae" usually do not require
Impossible Is Nothing (Tonic Breed song) the song, he comes out with another girl. The lyrics of the song, written by Svendsen, is about a person trying to make opinions and statements not influenced by what other people think of him/her. Impossible Is Nothing (Tonic Breed song) "Impossible is Nothing" is a song by heavy metal band Tonic Breed. It is the only song release from the band not to appear on a full-length studio album. The song was recorded in What it's Worth Studios in Råde, Norway, and is the first song by Tonic Breed to include Thomas Koksvik on lead guitar. On drums, the