Malaria with other antimalarials (known as artemisinin-combination therapy, or ACT), which decreases resistance to any single drug component. These additional antimalarials include: amodiaquine, lumefantrine, mefloquine or sulfadoxine/pyrimethamine. Another recommended combination is dihydroartemisinin and piperaquine. ACT is about 90% effective when used to treat uncomplicated malaria. To treat malaria during pregnancy, the WHO recommends the use of quinine plus clindamycin early in the pregnancy (1st trimester), and ACT in later stages (2nd and 3rd trimesters). In the 2000s (decade), malaria with partial resistance to artemisins emerged in Southeast Asia. Infection with "P. vivax", "P. ovale" or "P. malariae" usually do not require
Imagine No Malaria four key components: prevention, treatment, education, and communications. Building on the success of "Nothing But Nets", Imagine No Malaria is often thought of as Nets Plus. Insecticide-treated mosquito nets are still the best way to prevent malaria, however, other measures like draining standing water where the insects breed, trimming foliage and proper sanitation, are also critical to preventing malaria. The United Methodist Church has been working in Africa for more than 160 years. The church has the infrastructure of more than 300 clinics and hospitals in Africa to treat many patients. The Imagine No Malaria campaign has the goal of