Low kick sciatic nerve, which is the longest and widest nerve in the human body, beginning in the lower back and running through the buttocks all the way to the lower limb, is a frequent target for low kicks. The most common defense against a low kick is known as "checking", where the leg is bent and brought up to protect the thigh. This causes the kicker to slam their shin into the defending fighters' shin or knee, causing pain and damage to the offender. In some instances, a well executed check of a low kick can break the leg of the
Unethical human experimentation in the United States was now required for all research projects involving human subjects. Under the guidelines, seven research projects involving chemical weapons and human subjects were submitted by the Chemical Corps for Secretary of the Army approval in August 1953. One project involved vesicants, one involved phosgene, and five were experiments which involved nerve agents; all seven were approved. The guidelines, however, left a loophole; they did not define what types of experiments and tests required such approval from the Secretary. Operation Top Hat was among the numerous projects not submitted for approval. It was termed a "local field exercise" by the Army