Tonic water by mass), while the daily therapeutic dose of quinine is in the range of 500–1000 mg, and 10 mg/kg every eight hours for effective malaria prevention (2100 mg daily for a 70 kg adult). Still, it is often recommended as a relief for leg cramps but medical research suggests some care is needed in monitoring doses. Because of quinine's risks, the FDA cautions consumers against using "off-label" quinine drugs to treat leg cramps. Tonic water is often used as a drink mixer for cocktails, especially gin and tonic. Vodka tonic is also popular. Tonic water with lemon or lime flavor
Avian malaria prevalence and host traits such as nesting and foraging height, sexual dimorphism or even incubation time length. So far, the effects of this disease in wild populations is poorly understood. There exists a lot of controversy on what corresponds as a species in avian malaria parasites. The latin binomials nomenclature used to describe "Plasmodium" and "Hemoproteus" parasites is based on a restricted set of morphological characteristics and the restriction to which parasites of birds they are able to infect. Therefore, considering co-speciation events or even species diversity for malaria parasites is surrounded by a lot of disagreement. Molecular tools have