Mozart and smallpox the imperial family were successful, and led to greater public acceptance for the procedure. Smallpox struck the Mozart family again in the next generation: Nannerl's eldest son Leopold and two of her stepchildren caught the disease during an outbreak in the Salzburg area in 1787. All three children survived. In 1796, the discovery of vaccination—the use of the related cowpox virus to immunize against smallpox—by Edward Jenner revolutionized the ability of medicine to deal with smallpox. Vaccination reached Vienna around 1800, when yet another local epidemic created impetus for its adoption. One of the doctors trained in the Vienna campaign,
1978 smallpox outbreak in the United Kingdom were considered to be a threat to the success of the World Health Organization's smallpox eradication programme. On 11 August 1978, Parker (who had been vaccinated against smallpox in 1966, but not since) fell ill; she had a headache and pains in her muscles. She developed spots that were thought to be a benign rash, or chickenpox. On 20 August at 3pm, she was admitted to East Birmingham (now Heartlands) Hospital and a clinical diagnosis of "Variola major", the most serious type of smallpox, was made by consultant Alasdair Geddes. By this time the rash had spread and covered all