Tonic water by mass), while the daily therapeutic dose of quinine is in the range of 500–1000 mg, and 10 mg/kg every eight hours for effective malaria prevention (2100 mg daily for a 70 kg adult). Still, it is often recommended as a relief for leg cramps but medical research suggests some care is needed in monitoring doses. Because of quinine's risks, the FDA cautions consumers against using "off-label" quinine drugs to treat leg cramps. Tonic water is often used as a drink mixer for cocktails, especially gin and tonic. Vodka tonic is also popular. Tonic water with lemon or lime flavor
Tonic sol-fa as in staff notation) and colons designating beats within the measure. Time signatures and rests are not used. Tonic sol-fa Tonic sol-fa (or tonic sol-fah) is a pedagogical technique for teaching sight-singing, invented by Sarah Ann Glover (1785–1867) of Norwich, England and popularised by John Curwen who adapted it from a number of earlier musical systems. It uses a system of musical notation based on movable do solfège, whereby every tone is given a name according to its relationship with other tones in the key: the usual staff notation is replaced with anglicized solfège syllables (e.g. "do, re, mi, fa,