Smallpox vaccine get to a populated place. The world health system is completely unprepared for this." In the United Kingdom, controversy occurred regarding the company which had been contracted to supply the vaccine. This was because of the political connections of its owner, Paul Drayson, and questions over the choice of vaccine strain. The strain was different from that used in the United States. Plans for mass vaccinations in the United States stalled as the necessity of the inoculation came into question. Smallpox vaccine Smallpox vaccine, the first successful vaccine to be developed, was introduced by Edward Jenner in 1796. He followed
History of smallpox in Mexico caused Viceroy Félix Calleja to take preventive measures like fumigations and vaccination, which were successful. There were sporadic outbreaks until 1826 when smallpox appeared in Yucatán, Tabasco and Veracruz brought by North American ships. In 1828, there were reported cases in Hidalgo, Oaxaca, State of Mexico, Guerrero, Chiapas, Chihuahua and Mexico City. Efforts to eradicate smallpox in Mexico started with Dr José Ignacio Bartolache who wrote a book in 1779 about smallpox called “Instrucción que puede servir para que se cure a los enfermos de las viruelas epidemicas que ahora se padecen en México”(Instructions that may help to cure smallpox