Nuclear reaction Common light particles are often abbreviated in this shorthand, typically p for proton, n for neutron, d for deuteron, α representing an alpha particle or helium-4, β for beta particle or electron, γ for gamma photon, etc. The reaction above would be written as Li-6(d,α)α. In 1919, Ernest Rutherford was able to accomplish transmutation of nitrogen into oxygen at the University of Manchester, using alpha particles directed at nitrogen N + α → O + p. This was the first observation of an induced nuclear reaction, that is, a reaction in which particles from one decay are used to transform
Hepatocyte nuclear factor 4 alpha Hepatocyte nuclear factor 4 alpha Hepatocyte nuclear factor 4 alpha (HNF4A) also known as NR2A1 (nuclear receptor subfamily 2, group A, member 1) is a nuclear receptor that in humans is encoded by the "HNF4A" gene. HNF-4α is a nuclear transcription factor that binds DNA as a homodimer. The encoded protein controls the expression of several genes, including hepatocyte nuclear factor 1 alpha, a transcription factor which regulates the expression of several hepatic genes. This gene plays a role in development of the , , and . Alternative splicing of this gene results in multiple transcript variants. HNF4A is required