Copper for treatment of Wilson's disease have been investigated for use in cancer therapy. Copper is an essential trace element in plants and animals, but not all microorganisms. The human body contains copper at a level of about 1.4 to 2.1 mg per kg of body mass. Copper is absorbed in the gut, then transported to the liver bound to albumin. After processing in the liver, copper is distributed to other tissues in a second phase, which involves the protein ceruloplasmin, carrying the majority of copper in blood. Ceruloplasmin also carries the copper that is excreted in milk, and is particularly
Alcohol-related brain damage damage to the limbic system. This may lead to troubles recognizing emotional facial expressions and “interpreting nonverbal emotional cues". Binge drinking, or heavy episodic drinking, can lead to damage in the limbic system that occurs after a relatively short period of time. This brain damage increases the risk of dementia and abnormalities in mood and cognitive abilities. Binge drinkers also have an increased risk of developing chronic alcoholism.Alcoholism is also associated with many other health problems including memory disorders, high blood pressure, muscle weakness, heart problems, anaemia, low immune function, liver disease, disorders of the digestive system, and pancreatic problems.