Gin and tonic plasma levels at the lower limit of therapeutic efficacy and may, in fact, cause transitory suppression of parasites". This method of consumption of quinine was impractical for malaria prophylaxis, as the amount of drug needed "can not be maintained with even large amounts of tonic". The authors conclude that it is not an effective form of treatment for malaria. In Spain, a variation on the drink called Gin-Tonic has become popular. This differs from a traditional gin and tonic as it is served in a balloon glass (copa de balon) or coupe glass with plenty of ice and a garnish
Human genetic resistance to malaria ways that have a detrimental effect on the health or longevity of the individual. However, if the net effect of protection against malaria outweighs the other detrimental effects, the protective mutation will tend to be retained and propagated from generation to generation. These alterations which protect against malarial infections but impair red blood cells are generally considered blood disorders, since they tend to have overt and detrimental effects. Their protective function has only in recent times, been discovered and acknowledged. Some of these disorders are known by fanciful and cryptic names like sickle-cell anemia, thalassaemia, glucose-6-phosphate dehydrogenase deficiency, ovalocytosis, elliptocytosis