Calcium-induced calcium release of CICR across the cell causes the significant increase in cytosolic Ca that is important in activating muscle contraction. Calcium-induced calcium release Calcium-induced calcium release (CICR) describes a biological process whereby calcium is able to activate calcium release from intracellular Ca stores (e.g., endoplasmic reticulum or sarcoplasmic reticulum). Although CICR was first proposed for skeletal muscle in the 1970s, it is now known that CICR is unlikely to be its primary mechanism for activating SR calcium release. Instead, CICR is thought to be crucial for excitation-contraction coupling in cardiac muscle and it is now obvious that CICR is a widely
Calcium carbide Calcium carbide Calcium carbide is a chemical compound with the chemical formula of CaC. Its main use industrially is in the production of acetylene and calcium cyanamide. The pure material is colorless, however pieces of technical-grade calcium carbide are grey or brown and consist of about 80–85% of CaC (the rest is CaO (calcium oxide), CaP (calcium phosphide), CaS (calcium sulfide), CaN (calcium nitride), SiC (silicon carbide), etc.). In the presence of trace moisture, technical-grade calcium carbide emits an unpleasant odor reminiscent of garlic. Applications of calcium carbide include manufacture of acetylene gas, and for generation of acetylene in carbide