Tonic water by mass), while the daily therapeutic dose of quinine is in the range of 500–1000 mg, and 10 mg/kg every eight hours for effective malaria prevention (2100 mg daily for a 70 kg adult). Still, it is often recommended as a relief for leg cramps but medical research suggests some care is needed in monitoring doses. Because of quinine's risks, the FDA cautions consumers against using "off-label" quinine drugs to treat leg cramps. Tonic water is often used as a drink mixer for cocktails, especially gin and tonic. Vodka tonic is also popular. Tonic water with lemon or lime flavor
Malaria and the Caribbean Malaria and the Caribbean The effects of malaria in the Caribbean represent an important chapter of the history of the region, due to its effects on the colonization of the islands and the corresponding impact on society and economy. During the early exploration of the Caribbean islands, there was no immunity of the local nativa population against diseases which were brought by European and African immigrants. Although the Caribbean today is considered “a tropical paradise”, the islands contributed a perfect level of moisture and heat to facilitate the spread of viral and bacterial organisms that led to the death of