Malaria with other antimalarials (known as artemisinin-combination therapy, or ACT), which decreases resistance to any single drug component. These additional antimalarials include: amodiaquine, lumefantrine, mefloquine or sulfadoxine/pyrimethamine. Another recommended combination is dihydroartemisinin and piperaquine. ACT is about 90% effective when used to treat uncomplicated malaria. To treat malaria during pregnancy, the WHO recommends the use of quinine plus clindamycin early in the pregnancy (1st trimester), and ACT in later stages (2nd and 3rd trimesters). In the 2000s (decade), malaria with partial resistance to artemisins emerged in Southeast Asia. Infection with "P. vivax", "P. ovale" or "P. malariae" usually do not require
Florida Water Florida Water and Eau de Cologne were recommended as appropriate for all, along with sachets for scenting the linen and fresh flowers in the corsage. Large quantities were also used by barbershops as cologne and aftershave. In the 1880s and 1890s Murray & Lanman Florida Water was advertised as "The Richest of all Perfumes" and "The most Popular Perfume in the World". Like other colognes of the era, Florida Water was valued for its refreshing and tonic nature as well as its scent, and could be used as a skin toner or as what we would now call a "body