Smallpox vaccine Smallpox vaccine Smallpox vaccine, the first successful vaccine to be developed, was introduced by Edward Jenner in 1796. He followed up his observation that milkmaids who had previously caught cowpox did not later catch smallpox by showing that inoculated cowpox protected against inoculated smallpox. Dryvax is a freeze-dried calf lymph smallpox vaccine. It is the world's oldest smallpox vaccine, created in the late 19th century by American Home Products, a predecessor of Wyeth. By the 1940s, Wyeth was the leading US manufacturer of the vaccine and the only manufacturer by the 1960s. After world health authorities declared smallpox had been
Renaissance in the Low Countries Renaissance in the Low Countries The Renaissance in the Low Countries was a cultural period in the Northern Renaissance that took place in around the 16th century in the Low Countries (corresponding to modern-day Belgium, the Netherlands and French Flanders). Culture in the Low Countries at the end of the 15th century was influenced by the Italian Renaissance, through trade via Bruges which made Flanders wealthy. Its nobles commissioned artists who became known across Europe. In science, the anatomist Andreas Vesalius led the way; in cartography, Gerardus Mercator's map assisted explorers and navigators. In art, Dutch and Flemish Renaissance painting