Calcium CH ligand with the bulkier C(CH) ligand on the other hand increases the compound's solubility, volatility, and kinetic stability. Natural calcium is a mixture of five stable isotopes (Ca, Ca, Ca, Ca, and Ca) and one isotope with a half-life so long that it can be considered stable for all practical purposes (Ca, with a half-life of about 4.3 × 10 years). Calcium is the first (lightest) element to have six naturally occurring isotopes. By far the most common isotope of calcium in nature is Ca, which makes up 96.941% of all natural calcium. It is produced in the silicon-burning
Calcium in biology effective January 1, 2010. Examples of allowed wording are shown below. In order to qualify for the calcium health claim, a dietary supplement much contain at least 20% of the Reference Dietary Intake, which for calcium means at least 260 mg/serving. In 2005 the FDA approved a Qualified Health Claim for calcium and hypertension, with suggested wording "Some scientific evidence suggests that calcium supplements may reduce the risk of hypertension. However, FDA has determined that the evidence is inconsistent and not conclusive." Evidence for pregnancy-induced hypertension and preeclamsia was considered inconclusive. The same year the FDA approved a QHC for