Gin and tonic plasma levels at the lower limit of therapeutic efficacy and may, in fact, cause transitory suppression of parasites". This method of consumption of quinine was impractical for malaria prophylaxis, as the amount of drug needed "can not be maintained with even large amounts of tonic". The authors conclude that it is not an effective form of treatment for malaria. In Spain, a variation on the drink called Gin-Tonic has become popular. This differs from a traditional gin and tonic as it is served in a balloon glass (copa de balon) or coupe glass with plenty of ice and a garnish
History of malaria and make them more susceptible to other diseases. Spanish missionaries found that fever was treated by Amerindians near Loxa (Peru) with powder from Peruvian bark (later established to be from any of several trees of genus "Cinchona"). It was used by the Quechua Indians of Peru to reduce the shaking effects caused by severe chills. Jesuit Brother Agostino Salumbrino (1561–1642), who lived in Lima and was an apothecary by training, observed the Quechua using the bark of the cinchona tree for that purpose. While its effect in treating malaria (and hence malaria-induced shivering) was unrelated to its effect in controlling