Opioid selling Indian opium which was smuggled into China in defiance of Chinese government bans. This led to the First (1839–1842) and Second Opium Wars (1856–1860) between China and Britain. In the 19th century, two major scientific advances were made that had far-reaching effects. Around 1804, German pharmacist Friedrich Sertürner isolated morphine from opium. He described its crystallization, structure, and pharmacological properties in a well-received paper in 1817. Morphine was the first alkaloid to be isolated from any medicinal plant, the beginning of modern scientific drug discovery. The second advance, nearly fifty years later, was the refinement of the hypodermic needle
History of Chinese immigration to the United Kingdom the opium trade. Britain defeated China and under the terms of the Treaty of Nanking in 1842, Hong Kong became a British colony. In 1857, the Second Opium War resulted in the unequal Treaties of Tianjin which included a clause allowing Britain and France to recruit Chinese to the British Colonies, North American, South America, and Australia as cheap labour (otherwise known as "Coolies") following the cessation of the slave trade. Forced to pay for defeat in these and other colonial wars, impoverished Chinese people were driven abroad where they were often treated with suspicion, hostility, and even violence. Cheap