Calcium benzoate Calcium benzoate Calcium benzoate refers to the calcium salt of benzoic acid. When used in the food industry as a preservative, its E number is E213 (INS number 213); it is approved for use as a food additive in the EU, USA and Australia and New Zealand. The formulas and structures of calcium carboxylate derivatives of calcium and related metals are complex. Generally the coordination number is eight and the carboxylates form Ca-O bonds. Another variable is the degree of hydration. It is preferentially used more than other benzoic acid salts or its esters in foods due to its better
N-type calcium channel when binding to the receptors, can inhibit the release of the pro-nociceptive neurotransmitters and neuromodulators that come from the central nerve terminals of the afferent neurons. This inhibition is what ultimately can stop the transmission of pain to the person from damaged cells. Ziconotide is an inorganic version of the ɷɷ-conotoxin, MVIIA. This medicine is able to inhibit the release of pro-nociceptive receptors, which will then block the transmission of pain. N-type calcium channel N-type calcium channels are voltage gated calcium channels that are distributed throughout the entire body. These channels are high voltage activated channels composed of alpha-1B subunits.