Pituitary gland help control the following body processes: Some of the diseases involving the pituitary gland are: All of the functions of the pituitary gland can be adversely affected by an over- or under-production of associated hormones. The pituitary gland is important for mediating the stress response, via the hypothalamic–pituitary–adrenal axis (HPA axis) Critically, pituitary gland growth during adolescence can be altered by early life stress such as childhood maltreatment or maternal dysphoric behavior. It has been demonstrated that, after controlling for age, sex, and BMI, larger quantities of DHEA and DHEA-S tended to be linked to larger pituitary volume. Additionally, a
Drug delivery to the brain because most molecules are transported across the barrier, it does a very effective job of maintaining homeostasis for the most vital organ of the human body. Because of the difficulty for drugs to pass through the blood–brain barrier, a study was conducted to determine the factors that influence a compound’s ability to transverse the blood–brain barrier. In this study, they examined several different factors to investigate diffusion across the blood–brain barrier. They used lipophilicity, Gibbs Adsorption Isotherm, a Co CMC Plot, and the surface area of the drug to water and air. They began by looking at compounds whose blood–brain