Pancreatic islets by scarce alpha, delta and PP cells in the periphery, human islets display alpha and beta cells in close relationship with each other throughout the cluster. Islets can influence each other through paracrine and autocrine communication, and beta cells are coupled electrically to six to seven other beta cells (but not to other cell types). The paracrine feedback system of the pancreatic islets has the following structure: A large number of G protein-coupled receptors (GPCRs) regulate the secretion of insulin, glucagon and somatostatin from pancreatic islets, and some of these GPCRs are the targets of drugs used to treat type-2
The Description of the Human Body The Description of the Human Body The Description of the Human Body () is an unfinished treatise written in 1647 by René Descartes (1596-1650). Descartes felt knowing oneself was particularly useful. This for him included medical knowledge. He hoped to cure and prevent disease, even to slow down aging. René Descartes believed the soul caused conscious thought. The body caused automatic functions like the beating of the heart and digestion he felt. The body was necessary for voluntary movement as well as the will. However, he believed the power to move the body was wrongly imagined to come from the