Pancreatic islets by scarce alpha, delta and PP cells in the periphery, human islets display alpha and beta cells in close relationship with each other throughout the cluster. Islets can influence each other through paracrine and autocrine communication, and beta cells are coupled electrically to six to seven other beta cells (but not to other cell types). The paracrine feedback system of the pancreatic islets has the following structure: A large number of G protein-coupled receptors (GPCRs) regulate the secretion of insulin, glucagon and somatostatin from pancreatic islets, and some of these GPCRs are the targets of drugs used to treat type-2
Ryan Langerhans again selected to the All-State team. That season, Langerhans also won 11 games as a pitcher. During his senior season in 1998, Langerhans batted .512, was named to the All-State team, was selected as a Nike All-American, was selected to play in the 1998 Texas High School All-Star Game, and was named Texas Player of the Year. Langerhans is one of five players who attended Round Rock High School and have played in the major leagues. The four other players are John Danks, Brian Gordon, Jordan Danks and Travis Schlichting. Ryan Langerhans's father, John Langerhans, was his coach while playing