Pancreatic islets by scarce alpha, delta and PP cells in the periphery, human islets display alpha and beta cells in close relationship with each other throughout the cluster. Islets can influence each other through paracrine and autocrine communication, and beta cells are coupled electrically to six to seven other beta cells (but not to other cell types). The paracrine feedback system of the pancreatic islets has the following structure: A large number of G protein-coupled receptors (GPCRs) regulate the secretion of insulin, glucagon and somatostatin from pancreatic islets, and some of these GPCRs are the targets of drugs used to treat type-2
Ryan Langerhans Ryan Langerhans Ryan David Langerhans (born February 20, 1980) is an American former professional baseball outfielder. Langerhans was drafted in the third round of the 1998 Major League Baseball draft by the Atlanta Braves, and made his debut with them in 2002. He has also played in Major League Baseball for the Oakland Athletics, Washington Nationals, Seattle Mariners, Los Angeles Angels of Anaheim, and Toronto Blue Jays. Langerhans attended Round Rock High School in Round Rock, Texas. During the 1996 season, Langerhans batted .442 and was selected to the All-State team. His next season, 1997, Langerhans batted .427 and was