Jaundice Vitamin D production. Bilirubin count is lowered through bowel movements and urination, so frequent and effective feedings are especially important. Yellow discoloration of the skin, especially on the palms and the soles, but not of the sclera or inside the mouth is due to carotenemia—a harmless condition. Jaundice itself is not a disease, but rather a sign of one of many possible underlying pathological processes that occur at some point along the normal physiological pathway of the metabolism of bilirubin in blood. When red blood cells have completed their life span of approximately 120 days, or when they are damaged,
Secret Garden: An Inky Treasure Hunt and Colouring Book colouring in her work, which was frequently done in black and white. Initially the publisher was reluctant to release such an unorthodox book. However they eventually relented and the first run quickly sold out. The book's success is frequently cited as starting the adult coloring book trend. The book is modelled after the Brodick Castle Gardens on the Isle of Arran where Basford played as a child. By August 2015, Secret Garden had sold 2 million copies worldwide and launched the colouring trend for adults. In 2013, Basford released a second book: "Enchanted Forest: An Inky Quest & Colouring Book",