Pancreatic islets by scarce alpha, delta and PP cells in the periphery, human islets display alpha and beta cells in close relationship with each other throughout the cluster. Islets can influence each other through paracrine and autocrine communication, and beta cells are coupled electrically to six to seven other beta cells (but not to other cell types). The paracrine feedback system of the pancreatic islets has the following structure: A large number of G protein-coupled receptors (GPCRs) regulate the secretion of insulin, glucagon and somatostatin from pancreatic islets, and some of these GPCRs are the targets of drugs used to treat type-2
Ryan Langerhans for the Round Rock baseball team. During his senior year, Langerhans signed a letter of intent with the University of Texas, however, after being drafted by the Atlanta Braves, Langerhans went straight to professional baseball. Langerhans made his professional debut in 1998 with the rookie-level GCL Braves of the Gulf Coast League. He batted .277 with 41 hits, 10 doubles, 4 triples, 2 home runs, and 19 RBIs. In 1999, Langerhans was promoted to the Class-A Macon Braves of the South Atlantic League. In 121 games, Langerhans batted .268 with 120 hits, 30 doubles, 1 triple, 9 home runs, 49