To Have and Have Not on 15 October 1937 to a first edition print-run of approximately 10,000 copies. Cosmopolitan Magazine published a section of the novel as "One Trip Across" in 1934; Esquire Magazine published a section as "The Tradesman's Return" in 1936. The novel was adapted into a 1944 film, starring Humphrey Bogart and Lauren Bacall. The film, directed by Howard Hawks, changed the story's setting from Key West to Martinique under the Vichy regime, and made significant alterations to the plot, including getting rid of Hemingway's Marxist overtones, and turning the story into a romantic thriller centering on the sparks going on between
Sleep and memory Results indicate that sleep deprivation does not significantly affect recognition of faces, but does produce a significant impairment of temporal memory (discriminating which face belonged to which set). Caffeine was found to have a greater effect on the sleep deprived group as compared to the placebo group deprived of sleep but still performed worse than both control groups. Sleep deprivation was also found to increase beliefs of being correct, especially if they were wrong. Brain imaging studies of those sleep deprived found that the greatest reduction in metabolic rate is in the prefrontal cortex. A blood-oxygen-level dependent (BOLD) fMRI was