Loperamide of a number of types of diarrhea. This includes control of acute nonspecific diarrhea, mild traveler's diarrhea, irritable bowel syndrome, chronic diarrhea due to bowel resection, and chronic diarrhea secondary to inflammatory bowel disease. It is also useful for reducing ileostomy output. Off-label uses for loperamide also include chemotherapy-induced diarrhea, especially related to irinotecan use. Loperamide should not be used as the primary treatment in cases of bloody diarrhea, acute exacerbation of ulcerative colitis, or bacterial enterocolitis. Loperamide is often compared to diphenoxylate. Recent studies suggest that loperamide is more effective and has lower neural side effects. Adverse drug reactions
What a Treat What a Treat was retired to broodmare duty at owner George Widener's Old Kenney Farm near Lexington, Kentucky, where he bred her to Never Bend. Following Widener's death in December 1971, on February 12, 1972 What a Treat was auctioned through the Keeneland Sales to a breeding syndicate from France for a then world record price for a broodmare of US$450,000. Of the foals she birthed for her new owners, her mating to Northern Dancer was the most successful, producing the 1974 colt Be My Guest. Although Be My Guest proved to be a good miler who won three Conditions