Jaundice management may involve treating infectious causes and stopping medication that could be contributing. Among newborns, depending on age and prematurity, a bilirubin greater than 4–21 mg/dL (68-360 µmol/L) may be treated with phototherapy or exchanged transfusion. The itchiness may be helped by draining the gallbladder or ursodeoxycholic acid. The word "jaundice" is from the French "jaunisse", meaning "yellow disease". The main sign of jaundice is a yellowish discoloration of the white area of the eye and the skin. Urine is dark in colour. Slight increases in serum bilirubin are best detected by examining the sclerae, which have a particular affinity
Secret Garden: An Inky Treasure Hunt and Colouring Book colouring in her work, which was frequently done in black and white. Initially the publisher was reluctant to release such an unorthodox book. However they eventually relented and the first run quickly sold out. The book's success is frequently cited as starting the adult coloring book trend. The book is modelled after the Brodick Castle Gardens on the Isle of Arran where Basford played as a child. By August 2015, Secret Garden had sold 2 million copies worldwide and launched the colouring trend for adults. In 2013, Basford released a second book: "Enchanted Forest: An Inky Quest & Colouring Book",