Loperamide/simethicone Loperamide/simethicone Loperamide/simethicone is combination medication marketed under the trade name Imodium Multi-Symptom Relief (formerly Imodium A-D Advanced) used to treat diarrhea and gas simultaneously. It is manufactured by the McNeil Consumer Healthcare Division of McNeil PPC, Inc. Loperamide is a μ-opioid receptor agonist that works in the intestines. Although it is an opioid, it has no effects on the central nervous system. It reduces diarrhea by slowing the transit time of contents through the intestinal tract thereby allowing more water to be reabsorbed from the intestinal lumen. Simethicone reduces gas by allowing smaller gas bubbles to coalesce into larger bubbles
What a Treat What a Treat What a Treat (foaled 1962 in Kentucky) was an American Thoroughbred racehorse who was voted the 1965 American Champion Three-Year-Old Filly and who was sold as a broodmare in 1972 at a world record price. Bred and raced by George D. Widener, Jr., she was conditioned for racing by future U.S. Racing Hall of Fame trainer Syl Veitch. As a three-year-old in 1965, What a Treat won seven of the top races for her age group, including a win over older stars Tosmah and Affectionately in capturing the Beldame Stakes. At age four, carrying high weight, What