Loperamide 1980s, prior to the expiration of US patent on 30 January 1990, McNeil company started to develop Imodium Advanced containing loperamide and simethicone for treating both diarrhea and gas. In March 1997, the company patented such combination. The drug was approved in June 1997 by the FDA as Imodium Multi-Symptom Relief in the form of a chewable tablet. In November 1993, loperamide was launched as an orally disintegrating tablet based on Zydis technology. Imodium Instant Melts from Johnson & Johnson is currently the only loperamide available in the form of orally disintegrating tablets. In 2013, loperamide in the form of
What a Treat races in England and Ireland, he is best remembered as one of the foundation sires responsible for turning Ireland's Coolmore Stud into one of the most important Thoroughbred breeding operations in the world. What a Treat What a Treat (foaled 1962 in Kentucky) was an American Thoroughbred racehorse who was voted the 1965 American Champion Three-Year-Old Filly and who was sold as a broodmare in 1972 at a world record price. Bred and raced by George D. Widener, Jr., she was conditioned for racing by future U.S. Racing Hall of Fame trainer Syl Veitch. As a three-year-old in 1965, What