Pancreatic islets by scarce alpha, delta and PP cells in the periphery, human islets display alpha and beta cells in close relationship with each other throughout the cluster. Islets can influence each other through paracrine and autocrine communication, and beta cells are coupled electrically to six to seven other beta cells (but not to other cell types). The paracrine feedback system of the pancreatic islets has the following structure: A large number of G protein-coupled receptors (GPCRs) regulate the secretion of insulin, glucagon and somatostatin from pancreatic islets, and some of these GPCRs are the targets of drugs used to treat type-2
Islets of Granada the islands and nearby peninsula. Islets of Granada The islets of Granada (Spanish: "Isletas de Granada") are located in Lake Nicaragua, just southeast of the city of Granada in Nicaragua. The islets are a group of 365 small islands scattered about the Asese peninsula. The islets are of volcanic origin, they were formed when the Mombacho volcano blew much of its cone into the lake thousands of years ago, thereby creating the archipelago. Most of the islets are covered with vegetation and rich with bird life. Many of the islets are occupied. Some are privately owned and hold homes or