Loperamide/simethicone Loperamide/simethicone Loperamide/simethicone is combination medication marketed under the trade name Imodium Multi-Symptom Relief (formerly Imodium A-D Advanced) used to treat diarrhea and gas simultaneously. It is manufactured by the McNeil Consumer Healthcare Division of McNeil PPC, Inc. Loperamide is a μ-opioid receptor agonist that works in the intestines. Although it is an opioid, it has no effects on the central nervous system. It reduces diarrhea by slowing the transit time of contents through the intestinal tract thereby allowing more water to be reabsorbed from the intestinal lumen. Simethicone reduces gas by allowing smaller gas bubbles to coalesce into larger bubbles
Charles Treat Stotsenburg, Philippines, remaining on active duty until retiring in 1922. In 1930 he was promoted to Major General on the retired list. Treat received the Army Distinguished Service Medal for his World War I service. He was also a recipient of the Order of the White Eagle (Serbia) with swords and the Italian Order of Saints Maurice and Lazarus. His Distinguished Service Medal citation reads: Treat resided in Washington, D.C., and died at Walter Reed Army Medical Center on October 11, 1941. He is buried at West Point Cemetery, Section 1, Site B-25. In 1889 Treat married Margaret Louise Cornell,