Loperamide/simethicone Loperamide/simethicone Loperamide/simethicone is combination medication marketed under the trade name Imodium Multi-Symptom Relief (formerly Imodium A-D Advanced) used to treat diarrhea and gas simultaneously. It is manufactured by the McNeil Consumer Healthcare Division of McNeil PPC, Inc. Loperamide is a μ-opioid receptor agonist that works in the intestines. Although it is an opioid, it has no effects on the central nervous system. It reduces diarrhea by slowing the transit time of contents through the intestinal tract thereby allowing more water to be reabsorbed from the intestinal lumen. Simethicone reduces gas by allowing smaller gas bubbles to coalesce into larger bubbles
Medical tattoo Medical tattoo A medical tattoo is a tattoo used to treat a condition, communicate information, or mark a body location. A crude practice of corneal tattooing was performed by Galen in 150 CE. He tried to cover leukomatous opacities of the cornea by cauterizing the surface with a heated stilet and applying powdered nutgalls and iron or pulverized pomegranate bark mixed with copper salt; the practice was revived in the 1800s. With the rise of Christianity, tattooing declined and eventually became banned by a papal edict in 787 CE. The practice of corneal tattooing was revived by Louis Von Wecker