Loperamide of a number of types of diarrhea. This includes control of acute nonspecific diarrhea, mild traveler's diarrhea, irritable bowel syndrome, chronic diarrhea due to bowel resection, and chronic diarrhea secondary to inflammatory bowel disease. It is also useful for reducing ileostomy output. Off-label uses for loperamide also include chemotherapy-induced diarrhea, especially related to irinotecan use. Loperamide should not be used as the primary treatment in cases of bloody diarrhea, acute exacerbation of ulcerative colitis, or bacterial enterocolitis. Loperamide is often compared to diphenoxylate. Recent studies suggest that loperamide is more effective and has lower neural side effects. Adverse drug reactions
Knaster's condition Knaster's condition In mathematics, a partially ordered set "P" is said to have Knaster's condition upwards (sometimes property (K)) if any uncountable subset "A" of "P" has an upwards-linked uncountable subset. An analogous definition applies to Knaster's condition downwards. The property is named after Polish mathematician Bronisław Knaster. Knaster's condition implies the countable chain condition (ccc), and it is sometimes used in conjunction with a weaker form of Martin's axiom, where the ccc requirement is replaced with Knaster's condition. Not unlike ccc, Knaster's condition is also sometimes used as a property of a topological space, in which case it means