Pancreatic islets by scarce alpha, delta and PP cells in the periphery, human islets display alpha and beta cells in close relationship with each other throughout the cluster. Islets can influence each other through paracrine and autocrine communication, and beta cells are coupled electrically to six to seven other beta cells (but not to other cell types). The paracrine feedback system of the pancreatic islets has the following structure: A large number of G protein-coupled receptors (GPCRs) regulate the secretion of insulin, glucagon and somatostatin from pancreatic islets, and some of these GPCRs are the targets of drugs used to treat type-2
Development of the human body Development of the human body Human development is the process of growth to maturity. The process begins with fertilisation, where an egg released from the ovary of a female is penetrated by a sperm cell from a male. The egg then lodges in the uterus, where an embryo and later fetus develop until birth. Further growth and development continues after birth, and includes both physical and psychological development, influenced by genetic, hormonal, environmental and other factors. This continues throughout life, through childhood, and adolescence into adulthood. Development before birth, or prenatal development () is the process in which an embryo