Kargopolsky District subordinated to the central administration of Northern Krai. In 1936, the krai was transformed into Northern Oblast. In 1937, Northern Oblast itself was split into Arkhangelsk Oblast and Vologda Oblast. Kargopolsky District remained in Arkhangelsk Oblast ever since. The district is almost exclusively located in the basin of the Onega River, which is the biggest river in the district, and belongs to the basin of the White Sea. The source of the Onega is Lake Lacha, which is the biggest lake in the district. The northeastern shore of Lake Vozhe, also in the basin of the Onega, belongs to Kargopolsky
Arkhangelsk Oblast also navigable in the lower course. The Onega is not navigable except for the two relatively short stretches because of the rapids. However, except for the lower course of the Vychegda and some parts of the Northern Dvina, there is currently very little or no regular passenger navigation on these rivers. They are used for cargo traffic though. In 1765, a road was built between Saint-Petersburg and Arkhangelsk, mainly for postal service. The road still exists and passes Kargopol and Plesetsk, and it has been paved in 2011. One of the principal highways in Russia, M8, connects Moscow and Arkhangelsk,