Pancreatic islets and transdifferentiate into beta cells in both healthy and diabetic human and mouse pancreatic islets, a possible future source for beta cell regeneration. Pancreatic islets The pancreatic islets or islets of Langerhans are the regions of the pancreas that contain its endocrine (hormone-producing) cells, discovered in 1869 by German pathological anatomist Paul Langerhans. The pancreatic islets constitute 1 to 2% of the pancreas volume and receive 10–15% of its blood flow. The pancreatic islets are arranged in density routes throughout the human pancreas, and are important in the metabolism of glucose. There are about 3 million islets distributed in the
Ryan Langerhans On April 7, Langerhans was designated for assignment to make room for Jesús Colomé. On December 14, 2010, the Mariners again re-signed Langerhans to a minor league contract. On May 9, 2011, Langerhans was again designated for assignment to make room for Mike Wilson. On July 29, 2011, Langerhans was traded to the Arizona Diamondbacks for cash considerations. Langerhans signed a minor league contract with the Los Angeles Angels of Anaheim on December 23, 2011. Ryan was recalled by the Angels on May 14, 2012, when Torii Hunter was placed on the restricted list. On May 20, Langerhans was removed