Loperamide have negative effects from rebound constipation. If a suspicion exists of diarrhea associated with organisms that can penetrate the intestinal walls, such as or "Salmonella", loperamide is contraindicated as a primary treatment. Loperamide treatment is not used in symptomatic "C. difficile" infections, as it increases the risk of toxin retention and precipitation of toxic megacolon. Loperamide should be administered with caution to people with liver failure due to reduced first-pass metabolism. Additionally, caution should be used when treating people with advanced HIV, as cases of both viral and bacterial toxic megacolon have been reported. If abdominal distension is noted, therapy
Facility condition index was a strictly informal tool that Thomas and Richardson used while working for the Navy. It was developed and adopted as an industry benchmark by AME. To calculate an FCI a facility manager needs to quantify the cost of maintenance, repair and replacement deficiencies. This is typically the outcome of a Facility Condition Assessment. The current replacement value is defined as what monetary value the organization places on the facility. The FCI is a relative indicator of condition, and should be tracked over time to maximize its benefit. It is advantageous to define condition ratings based on ranges of the