Loperamide Loperamide Loperamide, sold under the brand name Imodium, among others, is a medication used to decrease the frequency of diarrhea. It is often used for this purpose in gastroenteritis, inflammatory bowel disease, and short bowel syndrome. It is not recommended for those with blood in the stool. The medication is taken by mouth. Common side effects include abdominal pain, constipation, sleepiness, vomiting, and a dry mouth. It may increase the risk of toxic megacolon. Loperamide's safety in pregnancy is unclear, but no evidence of harm has been found. It appears to be safe in breastfeeding. It is an opioid with
What Is to Be Done? (Tolstoy) What Is to Be Done? (Tolstoy) What Is To Be Done? (sometimes translated as What Then Must We Do?) is a non-fiction work by Leo Tolstoy, in which Tolstoy describes the social conditions of Russia in his day. Tolstoy completed the book in 1886, and the first English language publication came in 1887 as What To Do?. A revised translation with the current title was published in 1899. The English title was also used for two better-known works by Nikolai Chernyshevsky and Vladimir Lenin; Tolstoy's Russian title is similar but not identical to Chernyshevsky's (and Lenin's), both of them sharing