Pancreatic islets by scarce alpha, delta and PP cells in the periphery, human islets display alpha and beta cells in close relationship with each other throughout the cluster. Islets can influence each other through paracrine and autocrine communication, and beta cells are coupled electrically to six to seven other beta cells (but not to other cell types). The paracrine feedback system of the pancreatic islets has the following structure: A large number of G protein-coupled receptors (GPCRs) regulate the secretion of insulin, glucagon and somatostatin from pancreatic islets, and some of these GPCRs are the targets of drugs used to treat type-2
Ryan Langerhans between the Double-A Greenville Braves and the Triple-A Richmond Braves. Langerhans was called up by the Braves in September. On September 5, in his second game of the season, Langerhans got his first major league hit coming against the Pittsburgh Pirates. Despite making his major league debut in 2002, Langerhans did not become an everyday big-league player until 2005, getting playing time for the Braves in all three outfield positions. He is part of the group of 18 rookie players nicknamed the "Baby Braves" that Atlanta called up from its minor league system during the 2005 season. Langerhans started 2006