Loperamide/simethicone Loperamide/simethicone Loperamide/simethicone is combination medication marketed under the trade name Imodium Multi-Symptom Relief (formerly Imodium A-D Advanced) used to treat diarrhea and gas simultaneously. It is manufactured by the McNeil Consumer Healthcare Division of McNeil PPC, Inc. Loperamide is a μ-opioid receptor agonist that works in the intestines. Although it is an opioid, it has no effects on the central nervous system. It reduces diarrhea by slowing the transit time of contents through the intestinal tract thereby allowing more water to be reabsorbed from the intestinal lumen. Simethicone reduces gas by allowing smaller gas bubbles to coalesce into larger bubbles
Murder Ain't What it Used to Be Murder Ain't What it Used to Be Murder Ain't What it Used to Be is the seventh episode of the popular 1969 ITC British television series "Randall and Hopkirk (Deceased)" starring Mike Pratt, Kenneth Cope and Annette Andre. Directed by Jeremy Summers, the episode was first broadcast on 2 November 1969 on ITV. Crime boss Paul Kirstner flies over to Great Britain from New York City to attend to "business" in London. Behind most of the rackets in Chicago, he hires Jeff to protect his daughter from any of his enemies whilst in London. However, Kirstner is being haunted by