Pancreatic islets by scarce alpha, delta and PP cells in the periphery, human islets display alpha and beta cells in close relationship with each other throughout the cluster. Islets can influence each other through paracrine and autocrine communication, and beta cells are coupled electrically to six to seven other beta cells (but not to other cell types). The paracrine feedback system of the pancreatic islets has the following structure: A large number of G protein-coupled receptors (GPCRs) regulate the secretion of insulin, glucagon and somatostatin from pancreatic islets, and some of these GPCRs are the targets of drugs used to treat type-2
Trumpeter Islets Trumpeter Islets The Trumpeter Islets comprise a group of two unpopulated islets, with a combined area of about a hectare, located close to the south-western coast of Tasmania, Australia. Situated some where the mouth of Port Davey meets the Southern Ocean, the island is part of the Trumpeter Islets Group, and comprises part of the Southwest National Park and the Tasmanian Wilderness World Heritage Site. The islets are part of the Port Davey Islands Important Bird Area, so identified by BirdLife International because of its importance for breeding seabirds. Recorded breeding seabird and wader species are the little penguin (1000