Pancreatic islets by scarce alpha, delta and PP cells in the periphery, human islets display alpha and beta cells in close relationship with each other throughout the cluster. Islets can influence each other through paracrine and autocrine communication, and beta cells are coupled electrically to six to seven other beta cells (but not to other cell types). The paracrine feedback system of the pancreatic islets has the following structure: A large number of G protein-coupled receptors (GPCRs) regulate the secretion of insulin, glucagon and somatostatin from pancreatic islets, and some of these GPCRs are the targets of drugs used to treat type-2
Adrift Just Off the Islets of Langerhans referred to the tale as "one of (Ellison's) most ambitious and provocative tales to date." Adrift Just Off the Islets of Langerhans "Adrift Just Off the Islets of Langerhans: Latitude 38° 54' N, Longitude 77° 00' 13" W" is an award-winning 1974 science fiction novelette by Harlan Ellison. It was originally published in "The Magazine of Fantasy & Science Fiction" in October 1974, and subsequently republished in Ellison's 1975 anthology "Deathbird Stories", in the 1991 Byron Preiss-edited anthology "The Ultimate Werewolf", and in Ellison's 2006 anthology "The Essential Ellison: A 50 Year Retrospective". Larry Talbot wants to die, but cannot