Epsilon cell Epsilon cell Epsilon cells (ε-cells) are endocrine cells found in the Islets of Langerhans and produce the hormone ghrelin. They were discovered in mice. In human fetal pancreases, single epsilon cells scattered in primitive exocrine tissue were observed to start aggregating into clusters after gestational week 13. From gestational week 21, epsilon cells were observed around developing islets, forming an almost continuous layer at the rim of the islets. In adult pancreas samples, they remained localized on the mantle of the islets in different amounts. Production of ghrelin with insulin, glucagon, or somatostatin was not detected during development. Co-production with
Development of the human body characteristics, the "filling in" of the child's body; from girl to woman, from boy to man. Biologically, an adult is a human or other organism that has reached sexual maturity. In human context, the term "adult" additionally has meanings associated with social and legal concepts. In contrast to a "minor", a legal adult is a person who has attained the age of majority and is therefore regarded as independent, self-sufficient, and responsible. The typical age of attaining adulthood is 18, although definition may vary by legal rights and country. Human adulthood encompasses psychological adult development. Definitions of adulthood are often