Patrick Edward McGovern ca. 7000-6600 B.C. It was a mixed fermented beverage of rice, honey, and grape and/or hawthorn ("Crataegus pinnatifida" and "C. cuneata") fruit. The laboratory and collaborators began studying some of the most ancient chocolate from ancient Mesoamerica (ca. 1400-1100 B.C.) in 2004 Jars from Puerto Escondido in Honduras were in the shape of the cacao ("Theobroma cacao") pod or fruit, as if to advertise the contents as being a chocolate beverage. The fruit's sweet pulp contains about 15% sugar, which naturally ferments to a 5 to 7% alcoholic beverage. This beverage might have led to the domestication of the tree.
Cacao necrosis virus Cacao necrosis virus "Cacao necrosis virus" (CNV) is a plant pathogenic virus of the genus "nepovirus" that infects "Theobroma cacao" en natura causing cacao necrosis disease. CNV is considered synonymous with Strain S of cacao swollen shoot virus. Unlike cacao swollen-shoot virus, it is not transmitted by mealybugs nor vectored by aphids, beetles or leafhoppers that also commonly infest cacao. It is serologically, distantly related to Tomato black ring virus and very distantly related to Hungarian Chrome Mosaic virus. Cacao necrosis virus is restricted to systemic infection of "Theobroma cacao" in nature. Symptoms on cacao include an acute stage showing