History of diabetes further clarified in 1921, when Sir Frederick Grant Banting and Charles Herbert Best repeated the work of Von Mering and Minkowski, and went further to demonstrate they could reverse induced diabetes in dogs by giving them an extract from the pancreatic islets of Langerhans of healthy dogs. The islets of Langerhans was discovered in 1869 by an anatomist named Paul Langerhans. He identified the keys cells in the pancreas which produce the main substance that controls glucose levels in the body. Banting, Best, and colleagues (especially the chemist Collip) went on to purify the hormone insulin from bovine pancreases at
Chain Islets Chain Islets The Chain Islets and Great Chain Island (occasionally Great Chain Islet) are a group of at least 18 islets situated off the east coast of Oak Bay, British Columbia, Canada. They lie in Mayor Channel about halfway between Mary Tod Island (W) and Discovery Island (E). Most of the islets are very small, rocky, and are unnamed, except for Great Chain Island which is covered in grass and herbaceous cover with occasional shrub thickets. The islets are noted as an important gathering place for harbor seals in the summer and for many seabirds such as seagulls and cormorants.