Jaundice management may involve treating infectious causes and stopping medication that could be contributing. Among newborns, depending on age and prematurity, a bilirubin greater than 4–21 mg/dL (68-360 µmol/L) may be treated with phototherapy or exchanged transfusion. The itchiness may be helped by draining the gallbladder or ursodeoxycholic acid. The word "jaundice" is from the French "jaunisse", meaning "yellow disease". The main sign of jaundice is a yellowish discoloration of the white area of the eye and the skin. Urine is dark in colour. Slight increases in serum bilirubin are best detected by examining the sclerae, which have a particular affinity
Hand-colouring of photographs certainly impractical and dangerous. Hand-colouring remained the easiest and most effective method to produce full-colour photographic images until the mid-20th century when American Kodak introduced Kodachrome colour film. Though the hand-colouring of photographs was introduced in Europe, the technique gained considerable popularity in Japan, where the practice became a respected and refined art form beginning in the 1860s. It is possible that photographer Charles Parker and his artist partner William Parke Andrew were the first to produce such works in Japan, but the first to consistently employ hand-colouring in the country were the photographer Felice Beato and his partner, "The