Epsilon cell Epsilon cell Epsilon cells (ε-cells) are endocrine cells found in the Islets of Langerhans and produce the hormone ghrelin. They were discovered in mice. In human fetal pancreases, single epsilon cells scattered in primitive exocrine tissue were observed to start aggregating into clusters after gestational week 13. From gestational week 21, epsilon cells were observed around developing islets, forming an almost continuous layer at the rim of the islets. In adult pancreas samples, they remained localized on the mantle of the islets in different amounts. Production of ghrelin with insulin, glucagon, or somatostatin was not detected during development. Co-production with
Islets of Granada the islands and nearby peninsula. Islets of Granada The islets of Granada (Spanish: "Isletas de Granada") are located in Lake Nicaragua, just southeast of the city of Granada in Nicaragua. The islets are a group of 365 small islands scattered about the Asese peninsula. The islets are of volcanic origin, they were formed when the Mombacho volcano blew much of its cone into the lake thousands of years ago, thereby creating the archipelago. Most of the islets are covered with vegetation and rich with bird life. Many of the islets are occupied. Some are privately owned and hold homes or