History of diabetes further clarified in 1921, when Sir Frederick Grant Banting and Charles Herbert Best repeated the work of Von Mering and Minkowski, and went further to demonstrate they could reverse induced diabetes in dogs by giving them an extract from the pancreatic islets of Langerhans of healthy dogs. The islets of Langerhans was discovered in 1869 by an anatomist named Paul Langerhans. He identified the keys cells in the pancreas which produce the main substance that controls glucose levels in the body. Banting, Best, and colleagues (especially the chemist Collip) went on to purify the hormone insulin from bovine pancreases at
Ryan Langerhans again selected to the All-State team. That season, Langerhans also won 11 games as a pitcher. During his senior season in 1998, Langerhans batted .512, was named to the All-State team, was selected as a Nike All-American, was selected to play in the 1998 Texas High School All-Star Game, and was named Texas Player of the Year. Langerhans is one of five players who attended Round Rock High School and have played in the major leagues. The four other players are John Danks, Brian Gordon, Jordan Danks and Travis Schlichting. Ryan Langerhans's father, John Langerhans, was his coach while playing