Pancreatic islets and transdifferentiate into beta cells in both healthy and diabetic human and mouse pancreatic islets, a possible future source for beta cell regeneration. Pancreatic islets The pancreatic islets or islets of Langerhans are the regions of the pancreas that contain its endocrine (hormone-producing) cells, discovered in 1869 by German pathological anatomist Paul Langerhans. The pancreatic islets constitute 1 to 2% of the pancreas volume and receive 10–15% of its blood flow. The pancreatic islets are arranged in density routes throughout the human pancreas, and are important in the metabolism of glucose. There are about 3 million islets distributed in the
Apocrine sweat gland ducts. The tubules are wrapped in myoepithelial cells, which are more developed than in their eccrine gland counterparts. In hoofed animals and marsupials, apocrine glands act as the main thermoregulator, secreting watery sweat. For most mammals, however, apocrine sweat glands secrete an oily (and eventually smelly) compound that acts as a pheromone, territorial marker, and warning signal. Being sensitive to adrenaline, apocrine sweat glands are involved in emotional sweating in humans (induced by anxiety, stress, fear, sexual stimulation, and pain). In a five-month-old human fetus, apocrine glands are distributed all over the body; after a few weeks, they exist in