Loperamide/simethicone in the intestinal tract, making them easier to pass. Simethicone is not absorbed from the gastrointestinal tract so there are no systemic side effects. Anti-diarrheal medications should be avoided if diarrhea is secondary to an infection. Avoid using such products in the presence of fever, black stools, bloody stools, or stools containing mucus. Loperamide/simethicone Loperamide/simethicone is combination medication marketed under the trade name Imodium Multi-Symptom Relief (formerly Imodium A-D Advanced) used to treat diarrhea and gas simultaneously. It is manufactured by the McNeil Consumer Healthcare Division of McNeil PPC, Inc. Loperamide is a μ-opioid receptor agonist that works in the
What a Treat a Treat finished off the board in the February 15, 1966 Columbiana Handicap at Florida's Hialeah Park Race Track. On that same track, she then won the March 2 Black Helen Handicap and won again at Aqueduct Racetrack on April 14 before running second in the Bed O' Roses Handicap. The rest of her 1966 campaign brought What a Treat limited success, with her finishing off the board in important races such as the Diana Handicap, Ladies Handicap, and Maskette Handicap. Although What a Treat was in training in May 1967, her career ended that year without further racing success.