Jaundice Vitamin D production. Bilirubin count is lowered through bowel movements and urination, so frequent and effective feedings are especially important. Yellow discoloration of the skin, especially on the palms and the soles, but not of the sclera or inside the mouth is due to carotenemia—a harmless condition. Jaundice itself is not a disease, but rather a sign of one of many possible underlying pathological processes that occur at some point along the normal physiological pathway of the metabolism of bilirubin in blood. When red blood cells have completed their life span of approximately 120 days, or when they are damaged,
Hand-colouring of photographs certainly impractical and dangerous. Hand-colouring remained the easiest and most effective method to produce full-colour photographic images until the mid-20th century when American Kodak introduced Kodachrome colour film. Though the hand-colouring of photographs was introduced in Europe, the technique gained considerable popularity in Japan, where the practice became a respected and refined art form beginning in the 1860s. It is possible that photographer Charles Parker and his artist partner William Parke Andrew were the first to produce such works in Japan, but the first to consistently employ hand-colouring in the country were the photographer Felice Beato and his partner, "The