History of diabetes further clarified in 1921, when Sir Frederick Grant Banting and Charles Herbert Best repeated the work of Von Mering and Minkowski, and went further to demonstrate they could reverse induced diabetes in dogs by giving them an extract from the pancreatic islets of Langerhans of healthy dogs. The islets of Langerhans was discovered in 1869 by an anatomist named Paul Langerhans. He identified the keys cells in the pancreas which produce the main substance that controls glucose levels in the body. Banting, Best, and colleagues (especially the chemist Collip) went on to purify the hormone insulin from bovine pancreases at
Ryan Langerhans In 2002, Langerhans was promoted to the Double-A Greenville Braves of the Southern League. He batted .251 with 23 doubles, 2 triples, 9 home runs, and 62 RBIs in 109 games. Langerhans was called up to the Atlanta Braves from the Double-A Greenville Braves in April, 2002. He appeared in one game that season where he had one at-bat against the Houston Astros where he did not record a hit. He was sent back down to the minors to start the 2003 season where he batted a combined .261 with 33 doubles, 4 triples, 10 home runs, and 49 RBIs