Theobroma cacao as culinary, purposes. Some mixtures included maize, chili, vanilla ("Vanilla planifolia"), and honey. Archaeological evidence for use of cacao, while relatively sparse, has come from the recovery of whole cacao beans at Uaxactun, Guatemala and from the preservation of wood fragments of the cacao tree at Belize sites including Cuello and Pulltrouser Swamp. In addition, analysis of residues from ceramic vessels has found traces of theobromine and caffeine in early formative vessels from Puerto Escondido, Honduras (1100–900 BC) and in middle formative vessels from Colha, Belize (600–400 BC) using similar techniques to those used to extract chocolate residues from four
Cacao necrosis virus an effective cultural control method. This does not prevent new spread although spread is greatly reduced due to the limited dispersal of the nematode vector and subsequent monocyclic cycle of disease No resistant strains have been produced, though a resistant cacao tree may be the best possible management option looking forward. A similar transgenic approach taken to combat papaya ringspot virus could work for cacao based on the type of vector transmission. Seed transmission is estimated to be up to 24% depending on the plant species so cacao plantations should be planted from clean seed stock. This disease is currently