Loperamide bloody diarrhea. In 1990, all formulations for children of the antidiarrheal loperamide were banned in Pakistan. Loperamide is not recommended in the UK for use during pregnancy or by nursing mothers. In the US, loperamide is classified by the FDA as pregnancy category C. Studies in rat models have shown no teratogenicity, but sufficient studies in humans have not been conducted. One controlled, prospective study of 89 women exposed to loperamide during their first trimester of pregnancy showed no increased risk of malformations. This, however, was only one study with a small sample size. Loperamide can be present in breast
What Is to Be Done? (Tolstoy) What Is to Be Done? (Tolstoy) What Is To Be Done? (sometimes translated as What Then Must We Do?) is a non-fiction work by Leo Tolstoy, in which Tolstoy describes the social conditions of Russia in his day. Tolstoy completed the book in 1886, and the first English language publication came in 1887 as What To Do?. A revised translation with the current title was published in 1899. The English title was also used for two better-known works by Nikolai Chernyshevsky and Vladimir Lenin; Tolstoy's Russian title is similar but not identical to Chernyshevsky's (and Lenin's), both of them sharing