Loperamide/simethicone in the intestinal tract, making them easier to pass. Simethicone is not absorbed from the gastrointestinal tract so there are no systemic side effects. Anti-diarrheal medications should be avoided if diarrhea is secondary to an infection. Avoid using such products in the presence of fever, black stools, bloody stools, or stools containing mucus. Loperamide/simethicone Loperamide/simethicone is combination medication marketed under the trade name Imodium Multi-Symptom Relief (formerly Imodium A-D Advanced) used to treat diarrhea and gas simultaneously. It is manufactured by the McNeil Consumer Healthcare Division of McNeil PPC, Inc. Loperamide is a μ-opioid receptor agonist that works in the
Globus Medical Globus Medical Globus Medical, Inc., based in Audubon, Pennsylvania, is a medical device company focused on the design, development, and commercialization of musculoskeletal implants that promote healing in patients with spine disorders. Globus Medical is a publicly traded company and is listed on the NYSE under the symbol GMED. The company classifies its productsinto two categories: Innovative Fusion and Disruptive Technologies. The Innovative Fusion products are used in cervical, thoracolumbar, sacral, and interbody, corpectomy fusion procedures to treat degenerative, deformity, tumor, and trauma conditions. Globus Medical to date has developed a portfolio of spine products, releasing more than 150 products.