Bilious fever died from bilious fever. Modern diagnoses for the same symptoms would include a wide range of conditions and infections. Bilious fever (Latin bilis, "bile"): Refers to fever associated with excessive bile or bilirubin in the blood stream and tissues, causing jaundice (a yellow color in the skin or sclera of the eye). The most common cause was malaria. Viral hepatitis and bacterial infections of the blood stream (septicemia) may have caused a few of the deaths reported as bilious fever. Bilious fever Bilious fever was a medical diagnosis often used for any fever that exhibited the symptom of nausea or
Human skin color "Val60Leu" (rs1805005) and "Val92Met" (rs2228479) have been associated with reduced tanning response in European and/or East Asian populations. These alleles show no signs of positive selection and only occur in relatively small numbers, reaching a peak in Europe with around 28% of the population having at least one allele of one of the variations. A study of self-reported tanning ability and skin type in American non-Hispanic Caucasians found that "SLC24A5 Phe374Leu" is significantly associated with reduced tanning ability and also associated "TYR Arg402Gln" (rs1126809), "OCA2 Arg305Trp" (rs1800401) and a 2-SNP haplotype in "ASIP" (rs4911414 and rs1015362) to skin type variation