Insulin oscillation oscillations. The insulin oscillations are generated by pulsatile release of the hormone from the pancreas. Insulin originates from beta cells located in the islets of Langerhans. Since each islet contains up to 2000 beta cells and there are one million islets in the pancreas it is apparent that pulsatile secretion requires sophisticated synchronization both within and among the islets of Langerhans. Pulsatile insulin secretion from individual beta cells is driven by oscillation of the calcium concentration in the cells. In beta cells lacking contact, the periodicity of these oscillations is rather variable (2-10 min). However, within an islet of Langerhans
Ryan Langerhans In 2002, Langerhans was promoted to the Double-A Greenville Braves of the Southern League. He batted .251 with 23 doubles, 2 triples, 9 home runs, and 62 RBIs in 109 games. Langerhans was called up to the Atlanta Braves from the Double-A Greenville Braves in April, 2002. He appeared in one game that season where he had one at-bat against the Houston Astros where he did not record a hit. He was sent back down to the minors to start the 2003 season where he batted a combined .261 with 33 doubles, 4 triples, 10 home runs, and 49 RBIs