Theobroma cacao as culinary, purposes. Some mixtures included maize, chili, vanilla ("Vanilla planifolia"), and honey. Archaeological evidence for use of cacao, while relatively sparse, has come from the recovery of whole cacao beans at Uaxactun, Guatemala and from the preservation of wood fragments of the cacao tree at Belize sites including Cuello and Pulltrouser Swamp. In addition, analysis of residues from ceramic vessels has found traces of theobromine and caffeine in early formative vessels from Puerto Escondido, Honduras (1100–900 BC) and in middle formative vessels from Colha, Belize (600–400 BC) using similar techniques to those used to extract chocolate residues from four
Cacao swollen-shoot virus ambitious and costly eradication effort of any country in the world against a viral plant disease. Cacao swollen-shoot virus (CSSV) principally infects "Theobroma cacao" (cacao tree) and has a major effect on crop yields. Within one year of infection yields decrease by 25%, and within two years by 50%. The trees are usually killed within 3 to 4 years. Symptoms vary depending on the strain of virus. Main symptoms include: leaf chlorosis (interveinal), root necrosis, red vein banding in young leaves, small mottled pods, and stem/root swelling followed by die-back. CSSV has also been isolated from alternative hosts "Cola chlamydanta",