Patrick Edward McGovern ca. 7000-6600 B.C. It was a mixed fermented beverage of rice, honey, and grape and/or hawthorn ("Crataegus pinnatifida" and "C. cuneata") fruit. The laboratory and collaborators began studying some of the most ancient chocolate from ancient Mesoamerica (ca. 1400-1100 B.C.) in 2004 Jars from Puerto Escondido in Honduras were in the shape of the cacao ("Theobroma cacao") pod or fruit, as if to advertise the contents as being a chocolate beverage. The fruit's sweet pulp contains about 15% sugar, which naturally ferments to a 5 to 7% alcoholic beverage. This beverage might have led to the domestication of the tree.
Theobroma cacao of the cacao genome, of the Criollo cacao (of a landrace from Belize, B97-61/B2). In their publication, they reported a detailed analysis of the genomic and genetic data. The sequence of the cacao genome identified 28,798 protein-coding genes, compared to the roughly 23,000 protein-coding genes of the human genome. About 20% of the cacao genome consists of transposable elements, a low proportion compared to other plant species. Many genes were identified as coding for flavonoids, aromatic terpenes, theobromine and many other metabolites involved in cocoa flavor and quality traits, among which a relatively high proportion code for polyphenols, which constitute