Pancreatic islets by scarce alpha, delta and PP cells in the periphery, human islets display alpha and beta cells in close relationship with each other throughout the cluster. Islets can influence each other through paracrine and autocrine communication, and beta cells are coupled electrically to six to seven other beta cells (but not to other cell types). The paracrine feedback system of the pancreatic islets has the following structure: A large number of G protein-coupled receptors (GPCRs) regulate the secretion of insulin, glucagon and somatostatin from pancreatic islets, and some of these GPCRs are the targets of drugs used to treat type-2
Ryan Langerhans of the 11th inning. This was his first career game-winning homer. On August 25, 2009, Langerhans hit another game-winning home run against the Oakland Athletics off Craig Breslow on a two-ball two-strike pitch with one out and one runner on with the score tied 2-2 in the bottom of the tenth. Langerhans and his wife, Shari, live in Round Rock, Texas, where he also graduated from high school. In high school Langerhans improved his baseball skills and participated in cross country. Langerhans won a Class 5A state championship with the Round Rock High School Dragons in 1997. The Dragons were