Loperamide have negative effects from rebound constipation. If a suspicion exists of diarrhea associated with organisms that can penetrate the intestinal walls, such as or "Salmonella", loperamide is contraindicated as a primary treatment. Loperamide treatment is not used in symptomatic "C. difficile" infections, as it increases the risk of toxin retention and precipitation of toxic megacolon. Loperamide should be administered with caution to people with liver failure due to reduced first-pass metabolism. Additionally, caution should be used when treating people with advanced HIV, as cases of both viral and bacterial toxic megacolon have been reported. If abdominal distension is noted, therapy
No Way to Treat a Lady (film) writer's block, when writing "Boys and Girls Together" (published in 1964). He was inspired by an article about the Boston Strangler which suggested there might be two stranglers operating, and Goldman wondered what would happen if that were the case and they got jealous of each other. In 1987, Douglas J. Cohen adapted the film into a musical comedy, which was revived Off-Broadway by the York Theatre Company in 1996. That production was nominated for an Outer Critics Circle Award for Best Musical Revival. No Way to Treat a Lady (film) No Way to Treat a Lady is a 1968