Pancreatic islets and transdifferentiate into beta cells in both healthy and diabetic human and mouse pancreatic islets, a possible future source for beta cell regeneration. Pancreatic islets The pancreatic islets or islets of Langerhans are the regions of the pancreas that contain its endocrine (hormone-producing) cells, discovered in 1869 by German pathological anatomist Paul Langerhans. The pancreatic islets constitute 1 to 2% of the pancreas volume and receive 10–15% of its blood flow. The pancreatic islets are arranged in density routes throughout the human pancreas, and are important in the metabolism of glucose. There are about 3 million islets distributed in the
Ryan Langerhans from a game against the Padres when he injured his right shoulder after crashing into the left-field wall at San Diego's Petco Park. After coming off the 15-day disabled list, Langerhans was outrighted by the Angels. On October 6, 2012, Langerhans elected free agency. On December 18, 2012, the Toronto Blue Jays announced that Langerhans had been signed to a minor league contract with an invitation to major league spring training. Langerhans played for the Triple-A Buffalo Bisons during the 2013 season until he was released on June 21. After leaving the Bisons, Langerhans played for the Sugar Land Skeeters