Loperamide 1980s, prior to the expiration of US patent on 30 January 1990, McNeil company started to develop Imodium Advanced containing loperamide and simethicone for treating both diarrhea and gas. In March 1997, the company patented such combination. The drug was approved in June 1997 by the FDA as Imodium Multi-Symptom Relief in the form of a chewable tablet. In November 1993, loperamide was launched as an orally disintegrating tablet based on Zydis technology. Imodium Instant Melts from Johnson & Johnson is currently the only loperamide available in the form of orally disintegrating tablets. In 2013, loperamide in the form of
Treat You Better Show", and again on October 8, 2018 with Jimmy Fallon and his house band The Roots as backing using "classroom instruments". On November 20, 2016, Mendes performed the 'Treat You Better' at the 2016 American Music Awards. "Treat You Better" is being used in a series of commercials for Southwest Airlines. In July 2017 Swedish melodic metal band Sonic Syndicate released a cover version of the song. Treat You Better "Treat You Better" is a song recorded by Canadian singer and songwriter Shawn Mendes. It was co-written by Mendes with Teddy Geiger, and Scott Harris. It was released on June