Loperamide have negative effects from rebound constipation. If a suspicion exists of diarrhea associated with organisms that can penetrate the intestinal walls, such as or "Salmonella", loperamide is contraindicated as a primary treatment. Loperamide treatment is not used in symptomatic "C. difficile" infections, as it increases the risk of toxin retention and precipitation of toxic megacolon. Loperamide should be administered with caution to people with liver failure due to reduced first-pass metabolism. Additionally, caution should be used when treating people with advanced HIV, as cases of both viral and bacterial toxic megacolon have been reported. If abdominal distension is noted, therapy
Herb Treat the player-coach of Boston's first professional football team—the Boston Bulldogs in the first American Football League. The team lasted only six games, playing one home game in Braves Field and one in Fenway Park. In 1927, Treat played a role in the rescue of four youths who broke through the ice on Boston's Jamaica Pond. During World War II, Treat worked at Bethlehem Steel Co.'s Hingham Shipyard. He suffered serious head injuries in August 1943 when he was struck by an automobile while crossing the street in Weymouth, Massachusetts. He was in critical condition on arrival and spent several days