Epsilon cell Epsilon cell Epsilon cells (ε-cells) are endocrine cells found in the Islets of Langerhans and produce the hormone ghrelin. They were discovered in mice. In human fetal pancreases, single epsilon cells scattered in primitive exocrine tissue were observed to start aggregating into clusters after gestational week 13. From gestational week 21, epsilon cells were observed around developing islets, forming an almost continuous layer at the rim of the islets. In adult pancreas samples, they remained localized on the mantle of the islets in different amounts. Production of ghrelin with insulin, glucagon, or somatostatin was not detected during development. Co-production with
Passions of the Soul of a final cause in physics, the nature of his work on examining the origins and functions of desires in the human soul necessitates the existence of a final goal towards which the individual is working. The problem of the "Passions" treatise is also the problem of Cartesian Dualism. In the first part of his work, Descartes ponders the relationship which exists between the thinking substance and the body. For Descartes, the only link between these two substances is the pineal gland (art. 31), the place where the soul is attached to the body. The passions that Descartes studies are