Loperamide of a number of types of diarrhea. This includes control of acute nonspecific diarrhea, mild traveler's diarrhea, irritable bowel syndrome, chronic diarrhea due to bowel resection, and chronic diarrhea secondary to inflammatory bowel disease. It is also useful for reducing ileostomy output. Off-label uses for loperamide also include chemotherapy-induced diarrhea, especially related to irinotecan use. Loperamide should not be used as the primary treatment in cases of bloody diarrhea, acute exacerbation of ulcerative colitis, or bacterial enterocolitis. Loperamide is often compared to diphenoxylate. Recent studies suggest that loperamide is more effective and has lower neural side effects. Adverse drug reactions
What a Treat a Treat finished off the board in the February 15, 1966 Columbiana Handicap at Florida's Hialeah Park Race Track. On that same track, she then won the March 2 Black Helen Handicap and won again at Aqueduct Racetrack on April 14 before running second in the Bed O' Roses Handicap. The rest of her 1966 campaign brought What a Treat limited success, with her finishing off the board in important races such as the Diana Handicap, Ladies Handicap, and Maskette Handicap. Although What a Treat was in training in May 1967, her career ended that year without further racing success.