I Love to Laugh Mr. Wigg, is said to float because of an excess of "laughing gas", although it is clear that the term is not used in the chemical sense. So-called "laughing gas" (nitrous oxide) was one of the earliest effective anaesthetics developed in the Nineteenth century. it was popularised by dentists, for pain-free tooth extractions, as well as by showground novelty booths. Customers at the booth would be gassed and, as they were recovering from the drugged sleep they often felt euphoric and giggly. Hence the name. A famous 1931 British comedy sketch starring Cicely Courtneidge, called "Laughing Gas", was based on
Chemical ionization Chemical ionization Chemical ionization (CI) is a soft ionization technique used in mass spectrometry. This was first introduced by Burnaby Munson and Frank H. Field in 1966. This technique is a branch of gaseous ion-molecule chemistry. Reagent gas molecules are ionized by electron ionization, which subsequently react with analyte molecules in the gas phase in order to achieve ionization. Negative chemical ionization (NCI), charge-exchange chemical ionization and atmospheric-pressure chemical ionization (APCI) are some of the common variations of this technique. CI has several important applications in identification, structure elucidation and quantitation of organic compounds. Beside the applications in analytical chemistry,