Loperamide Loperamide Loperamide, sold under the brand name Imodium, among others, is a medication used to decrease the frequency of diarrhea. It is often used for this purpose in gastroenteritis, inflammatory bowel disease, and short bowel syndrome. It is not recommended for those with blood in the stool. The medication is taken by mouth. Common side effects include abdominal pain, constipation, sleepiness, vomiting, and a dry mouth. It may increase the risk of toxic megacolon. Loperamide's safety in pregnancy is unclear, but no evidence of harm has been found. It appears to be safe in breastfeeding. It is an opioid with
No Way to Treat a Lady (novel) No Way to Treat a Lady (novel) No Way to Treat a Lady is a 1964 novel by William Goldman. Goldman wrote the original novel while experiencing writer's block, when writing "Boys and Girls Together" (published in 1964). He was inspired by an article about the Boston Strangler which suggested there might be two stranglers operating, and Goldman wondered what would happen if that were the case and they got jealous of each other. (In the film adaptation, there is only one strangler; Goldman hated this change.) He says as he walked to his office, "the book simply jumped into