Loperamide/simethicone Loperamide/simethicone Loperamide/simethicone is combination medication marketed under the trade name Imodium Multi-Symptom Relief (formerly Imodium A-D Advanced) used to treat diarrhea and gas simultaneously. It is manufactured by the McNeil Consumer Healthcare Division of McNeil PPC, Inc. Loperamide is a μ-opioid receptor agonist that works in the intestines. Although it is an opioid, it has no effects on the central nervous system. It reduces diarrhea by slowing the transit time of contents through the intestinal tract thereby allowing more water to be reabsorbed from the intestinal lumen. Simethicone reduces gas by allowing smaller gas bubbles to coalesce into larger bubbles
Treat You Better Show", and again on October 8, 2018 with Jimmy Fallon and his house band The Roots as backing using "classroom instruments". On November 20, 2016, Mendes performed the 'Treat You Better' at the 2016 American Music Awards. "Treat You Better" is being used in a series of commercials for Southwest Airlines. In July 2017 Swedish melodic metal band Sonic Syndicate released a cover version of the song. Treat You Better "Treat You Better" is a song recorded by Canadian singer and songwriter Shawn Mendes. It was co-written by Mendes with Teddy Geiger, and Scott Harris. It was released on June