Theobromine Theobromine Theobromine, formerly known as xantheose, is a bitter alkaloid of the cacao plant, with the chemical formula CHNO. It is found in chocolate, as well as in a number of other foods, including the leaves of the tea plant, and the kola nut. It is classified as a xanthine alkaloid, others of which include theophylline and caffeine. The compounds differ in that caffeine has an extra methyl group (see under Pharmacology section). Despite its name, the compound contains no bromine—"theobromine" is derived from "Theobroma", the name of the genus of the cacao tree (which itself is made up of
Ceratocystis cacaofunesta Ceratocystis cacaofunesta Ceratocystis cacaofunesta is an ascomycete fungus that causes a wilt disease in cacao trees. It has led to significant economic losses in Latin America. Once considered to be a form of "Ceratocystis fimbriata", the fungus was described as a new species in 2005. The specific epithet "cacaofunesta" means "cacao-killing". Two closely related sublineages exist within this species, one centered in western Ecuador and the other containing isolates from Brazil, Colombia and Costa Rica. The disease known as "Ceratocystis wilt of cacao" (or "Mal de machete") is a serious disease of the cocoa tree ("Theobroma cacao") in Latin America.