Loperamide of a number of types of diarrhea. This includes control of acute nonspecific diarrhea, mild traveler's diarrhea, irritable bowel syndrome, chronic diarrhea due to bowel resection, and chronic diarrhea secondary to inflammatory bowel disease. It is also useful for reducing ileostomy output. Off-label uses for loperamide also include chemotherapy-induced diarrhea, especially related to irinotecan use. Loperamide should not be used as the primary treatment in cases of bloody diarrhea, acute exacerbation of ulcerative colitis, or bacterial enterocolitis. Loperamide is often compared to diphenoxylate. Recent studies suggest that loperamide is more effective and has lower neural side effects. Adverse drug reactions
Charles Treat Stotsenburg, Philippines, remaining on active duty until retiring in 1922. In 1930 he was promoted to Major General on the retired list. Treat received the Army Distinguished Service Medal for his World War I service. He was also a recipient of the Order of the White Eagle (Serbia) with swords and the Italian Order of Saints Maurice and Lazarus. His Distinguished Service Medal citation reads: Treat resided in Washington, D.C., and died at Walter Reed Army Medical Center on October 11, 1941. He is buried at West Point Cemetery, Section 1, Site B-25. In 1889 Treat married Margaret Louise Cornell,