Nucleic acid notation Nucleic acid notation The nucleic acid notation currently in use was first formalized by the International Union of Pure and Applied Chemistry (IUPAC) in 1970. This universally accepted notation uses the Roman characters G, C, A, and T, to represent the four nucleotides commonly found in deoxyribonucleic acids (DNA). Given the rapidly expanding role for genetic sequencing, synthesis, and analysis in biology, researchers have been compelled to develop alternate notations to further support the analysis and manipulation of genetic data. These notations generally exploit size, shape, and symmetry to accomplish these objectives. Degenerate base symbols in biochemistry are an IUPAC
Carboxylic acid the electron-withdrawing effect of the carbonyl bond, which makes the terminal oxygen-hydrogen bond weaker and thus makes acid dissociation more favorable (lowers pKa). Carboxylic acids can be seen as reduced or alkylated forms of the Lewis acid carbon dioxide; under some circumstances they can be decarboxylated to yield carbon dioxide. Carboxylic acids are commonly identified using their trivial names, and usually have the suffix "-ic acid". IUPAC-recommended names also exist; in this system, carboxylic acids have an "-oic acid" suffix. For example, butyric acid (CHCOH) is butanoic acid by IUPAC guidelines. The "-oic acid" nomenclature detail is based on the