Sciatic nerve Sciatic nerve The sciatic nerve (also called "ischiadic nerve", "ischiatic nerve") is a large nerve in humans and other animals. It begins in the lower back and runs through the buttock and down the lower limb. It is the longest and widest single nerve in the human body, going from the top of the leg to the foot on the posterior aspect. The sciatic nerve provides the connection to the nervous system for nearly the whole of the skin of the leg, the muscles of the back of the thigh, and those of the leg and foot. It is derived
Unethical human experimentation in the United States was now required for all research projects involving human subjects. Under the guidelines, seven research projects involving chemical weapons and human subjects were submitted by the Chemical Corps for Secretary of the Army approval in August 1953. One project involved vesicants, one involved phosgene, and five were experiments which involved nerve agents; all seven were approved. The guidelines, however, left a loophole; they did not define what types of experiments and tests required such approval from the Secretary. Operation Top Hat was among the numerous projects not submitted for approval. It was termed a "local field exercise" by the Army