Spinal nerve nerve roots result in typical patterns of neurologic defects (muscle weakness, abnormal sensation, changes in reflexes) that allow localization of the responsible lesion. There are several procedures used in sacral nerve stimulation for the treatment of various related disorders. Sciatica is generally caused by the compression of lumbar nerves L4, or L5 or sacral nerves S1, S2, or S3, or by compression of the sciatic nerve itself. Spinal nerve A spinal nerve is a mixed nerve, which carries motor, sensory, and autonomic signals between the spinal cord and the body. In the human body there are 31 pairs of spinal
Unethical human experimentation in the United States was now required for all research projects involving human subjects. Under the guidelines, seven research projects involving chemical weapons and human subjects were submitted by the Chemical Corps for Secretary of the Army approval in August 1953. One project involved vesicants, one involved phosgene, and five were experiments which involved nerve agents; all seven were approved. The guidelines, however, left a loophole; they did not define what types of experiments and tests required such approval from the Secretary. Operation Top Hat was among the numerous projects not submitted for approval. It was termed a "local field exercise" by the Army