Nucleic acid sequence Nucleic acid sequence A nucleic acid sequence is a succession of letters that indicate the order of nucleotides forming alleles within a DNA (using GACT) or RNA (GACU) molecule. By convention, sequences are usually presented from the 5' end to the 3' end. For DNA, the sense strand is used. Because nucleic acids are normally linear (unbranched) polymers, specifying the sequence is equivalent to defining the covalent structure of the entire molecule. For this reason, the nucleic acid sequence is also termed the primary structure. The sequence has capacity to represent information. Biological deoxyribonucleic acid represents the information which directs
Formic acid a volatile pH modifier in HPLC and capillary electrophoresis. Formic acid is a source for a formyl group for example in the formylation of methylaniline to N-methylformanilide in toluene. In synthetic organic chemistry, formic acid is often used as a source of hydride ion. The Eschweiler-Clarke reaction and the Leuckart-Wallach reaction are examples of this application. It, or more commonly its azeotrope with triethylamine, is also used as a source of hydrogen in transfer hydrogenation. As mentioned below, formic acid readily decomposes with concentrated sulfuric acid to form carbon monoxide. Formic acid shares most of the chemical properties of other