Nucleic acid hybridization Nucleic acid hybridization In molecular biology, hybridization (or hybridisation) is a phenomenon in which single-stranded deoxyribonucleic acid (DNA) or ribonucleic acid (RNA) molecules anneal to complementary DNA or RNA. Though a double-stranded DNA sequence is generally stable under physiological conditions, changing these conditions in the laboratory (generally by raising the surrounding temperature) will cause the molecules to separate into single strands. These strands are complementary to each other but may also be complementary to other sequences present in their surroundings. Lowering the surrounding temperature allows the single-stranded molecules to anneal or “hybridize” to each other. DNA replication and transcription of
What Work Is Fame" and "Growth" are direct accounts of two of Levine's jobs as a young man. "Fear and Fame" is based on a job Levine had cleaning out and refilling acid vats in his mid twenties. "Growth" is about the job Levine held at a soap factory at the age of fourteen. Many of Levine's poems are based on his experience growing up in Detroit. The titular poem, "What Work Is", is based on Levine's experience of waiting in a Detroit employment line. "The Right Cross" is related to a boxing teacher who taught Levine to defend himself while growing up