Nucleic acid hybridization natural positions within a chromosome). In 1969, the two scientists published a paper demonstrating that radioactive copies of a ribosomal DNA sequence could be used to detect complementary DNA sequences in the nucleus of a frog egg. Since those original observations, many refinements have increased the versatility and sensitivity of the procedure to the extent that in situ hybridization is now considered an essential tool in cytogenetics. Nucleic acid hybridization In molecular biology, hybridization (or hybridisation) is a phenomenon in which single-stranded deoxyribonucleic acid (DNA) or ribonucleic acid (RNA) molecules anneal to complementary DNA or RNA. Though a double-stranded DNA
Benzenesulfonic acid sometimes called alkaline fusion, initially affords the phenoxide salt: The process has been largely displaced by the Hock process, which generates less waste. Benzensulfonic acid is commonly used as the active ingredient in laundry detergent used in clothes washing machines. Benzenesulfonic acid is often used to convert to other specialty chemicals. A variety of pharmaceutical drugs are prepared as benzenesulfonate salts and are known as besilates (INN) or besylates (USAN). In a diluted form, it is also used as a polymer remover stripping agent. Benzenesulfonic acid Benzenesulfonic acid (conjugate base benzenesulfonate) is an organosulfur compound with the formula CHOS. It