Edward Downes after his health declined following a hip replacement. Lady Downes was diagnosed with terminal pancreatic cancer that metastasised to her liver, and given only weeks to live. Lady Downes wrote a letter to family explaining that she had decided against treatment and that: Sir Edward, aged 85, and Lady Downes, aged 74, ended their lives by assisted suicide at the Dignitas clinic in Zürich, Switzerland, on 10 July 2009. Although Joan did not want the children present, Dignitas encouraged it and "Ted and Joanie" were reported to be pleased when the time came. Their children issued a statement speaking of
Sir William Knyvett Humphrey Stafford, 1st Duke of Buckingham and Lady Anne Neville, by whom he had issue. His final marriage was to Lady Joan Courtenay, widow of Sir Roger Clifford, and daughter of Thomas de Courtenay, 5th Earl of Devon, a friend of York, and his wife, Lady Margaret Beaufort; they had no issue. Sir William Knyvett died December 2, 1515 in Wymondham, Norfolk. His children by his first wife, Alice Grey, were Sir Edmund Knyvett of Buckenham, who married Eleanor Tyrrell; Anne Knyvett who married John Thwaites, Esq.; Bennet Knyvett; and Elizabeth Knyvett. By his second wife, Lady Joan Stafford, Knyvett