Nasser Hejazi his nomination for 2005 presidential election. He was rejected by the Guardian Council of the Constitution of Islamic Republic of Iran, arguing his lack of political career prior to the election. Later on, he became a supporter of Ali Akbar Hashemi Rafsanjani. In 2009 presidential election, he supported Mir-Hossein Mousavi. He was an opponent to the Economic reform plan of President Mahmoud Ahmadinejad's Government. In April 2011, he made a statement regarding the plan: "I'm very sorry for our people, they have oil, petroleum and ... but some of them are poor". It is known that after this comment, he
Hossein Shariatmadari Mir Hossein Mousavi was trying to "escape punishment for murdering innocent people, holding riots, cooperating with foreigners and acting as America's fifth column inside the country" and called for Mousavi and former reformist President Mohammad Khatami to be tried in court for "horrible crimes and treason." In 2009, during the first contested presidential elections, Shariatmadari was announced that Mohammad Khatami would risk the same fate of Benazir Bhutto if he was elected. After the elections, alongside the Green Party protests, Shariatmadari accused Mir Hossein Mousavi of being a fifth column of the US and causing the deaths of many people.