History of genetics of the fruit fly "Drosophila melanogaster". In 1928, Frederick Griffith showed that genes could be transferred. In what is now known as Griffith's experiment, injections into a mouse of a deadly strain of bacteria that had been heat-killed transferred genetic information to a safe strain of the same bacteria, killing the mouse. A series of subsequent discoveries led to the realization decades later that the genetic material is made of DNA (deoxyribonucleic acid). In 1941, George Wells Beadle and Edward Lawrie Tatum showed that mutations in genes caused errors in specific steps in metabolic pathways. This showed that specific genes
Acetylenedicarboxylic acid separated and the latter is treated with sulfuric acid. Acetylenedicarboxylic acid is used in the synthesis of dimethyl acetylenedicarboxylate, an important laboratory reagent. The acid is commonly traded as a laboratory chemical. It can also be reacted with sulfur tetrafluoride to produce hexafluoro-2-butyne, a powerful dienophile for use in Diels-Alder reactions. Hydrogenacetylenedicarboxylate (often abbreviated as Hadc or HADC) is a monovalent anion of acetylenedicarboxylic acid with the formula CHO or <chem>HO2C-C#C-CO2-</chem>. The anion can be derived from acetylenedicarboxylic acid by removal of a single proton or from the acetylenedicarboxylate dianion by addition of a proton. The name is also used