Cast of ER Cast of ER "ER" is an American drama series that aired on NBC from September 19, 1994 until April 2, 2009. The series featured a large ensemble cast that changed dramatically over its long run. The main cast was augmented by a wealth of recurring characters and award-winning guest stars. The original starring cast consisted of Anthony Edwards as Dr. Mark Greene, George Clooney as Dr. Douglas "Doug" Ross, Sherry Stringfield as Dr. Susan Lewis, Noah Wyle as medical student (later Dr.) John Carter, and Eriq La Salle as Dr. Peter Benton. Julianna Margulies guest starred in the pilot as
Cast of ER at least one scene outside the ER, exploring one of the character's personal life. Storylines often include the character struggling with his or her family problems or a budding or failing romantic relationship. Although the point of view is very rarely from these character's perspective, they are nonetheless usually well rounded and have profound effects on the main characters. Cast of ER "ER" is an American drama series that aired on NBC from September 19, 1994 until April 2, 2009. The series featured a large ensemble cast that changed dramatically over its long run. The main cast was augmented by