History of genetics of the fruit fly "Drosophila melanogaster". In 1928, Frederick Griffith showed that genes could be transferred. In what is now known as Griffith's experiment, injections into a mouse of a deadly strain of bacteria that had been heat-killed transferred genetic information to a safe strain of the same bacteria, killing the mouse. A series of subsequent discoveries led to the realization decades later that the genetic material is made of DNA (deoxyribonucleic acid). In 1941, George Wells Beadle and Edward Lawrie Tatum showed that mutations in genes caused errors in specific steps in metabolic pathways. This showed that specific genes
2-Iodobenzoic acid is ejected, yielding a carbocation which is then attacked by highly nucleophilic I anion. The nitrous acid is usually generated "in situ" from sodium nitrite. 2-Iodobenzoic acid 2-Iodobenzoic acid, or "o"-iodobenzoic acid, is an organic compound with the formula ICHCOOH. The synthesis of 2-iodobenzoic acid "via" the diazotization of anthranilic acid is commonly performed in university organic chemistry labs. One of its most common uses is as a precursor for the preparation of IBX and Dess–Martin periodinane, both used as mild oxidants. 2-Iodobenzoic acid can be synthesized "via" a Sandmeyer reaction consisting of the diazotization of anthranilic acid followed by