Nucleic acid hybridization natural positions within a chromosome). In 1969, the two scientists published a paper demonstrating that radioactive copies of a ribosomal DNA sequence could be used to detect complementary DNA sequences in the nucleus of a frog egg. Since those original observations, many refinements have increased the versatility and sensitivity of the procedure to the extent that in situ hybridization is now considered an essential tool in cytogenetics. Nucleic acid hybridization In molecular biology, hybridization (or hybridisation) is a phenomenon in which single-stranded deoxyribonucleic acid (DNA) or ribonucleic acid (RNA) molecules anneal to complementary DNA or RNA. Though a double-stranded DNA
Docosapentaenoic acid omega-3 fats in humans, such as in inflammation mechanisms. Docosapentaenoic acid Docosapentaenoic acid (DPA) designates any straight chain 22:5 fatty acid, that is a straight chain open chain type of polyunsaturated fatty acid (PUFA) which contains 22 carbons and 5 double bonds. DPA is primarily used to designate two isomers, "all"-"cis"-4,7,10,13,16-docosapentaenoic acid (i.e. 4"Z",7"Z",10"Z",13"Z",16"Z"-docosapentaenoic acid) and "all"-"cis"-7,10,13,16,19-docosapentaenoic acid (i.e. 7"Z",10"Z",13"Z",16"Z",19"Z"-docosapentaenoic acid). They are also commonly termed n-6 DPA and n-3 DPA, respectively; these designations describes the position of the double bond being 6 or 3 carbons closest to the (omega) carbon at the methyl end of the molecule and is