Cast of ER Cast of ER "ER" is an American drama series that aired on NBC from September 19, 1994 until April 2, 2009. The series featured a large ensemble cast that changed dramatically over its long run. The main cast was augmented by a wealth of recurring characters and award-winning guest stars. The original starring cast consisted of Anthony Edwards as Dr. Mark Greene, George Clooney as Dr. Douglas "Doug" Ross, Sherry Stringfield as Dr. Susan Lewis, Noah Wyle as medical student (later Dr.) John Carter, and Eriq La Salle as Dr. Peter Benton. Julianna Margulies guest starred in the pilot as
Siddharth (actor) (2004), before he branched off to receive critical and commercial acclaim in Telugu and Hindi cinema through "Nuvvostanante Nenoddantana" (2005), "Rang De Basanti" and "Bommarillu" (2006). In the late 2000s, he established himself as a bankable lead actor in Telugu films and subsequently chose to become more selective with his projects, while also winning acclaim for his work as a carrom player in "Striker" (2010) and as a blind warrior in the fantasy film "Anaganaga O Dheerudu" (2011). In 2011, he returned to Tamil films after a sabbatical and produced Balaji Mohan's commercially successful romantic comedy "Kadhalil Sodhappuvadhu Yeppadi" (2012).