Cast of ER Cast of ER "ER" is an American drama series that aired on NBC from September 19, 1994 until April 2, 2009. The series featured a large ensemble cast that changed dramatically over its long run. The main cast was augmented by a wealth of recurring characters and award-winning guest stars. The original starring cast consisted of Anthony Edwards as Dr. Mark Greene, George Clooney as Dr. Douglas "Doug" Ross, Sherry Stringfield as Dr. Susan Lewis, Noah Wyle as medical student (later Dr.) John Carter, and Eriq La Salle as Dr. Peter Benton. Julianna Margulies guest starred in the pilot as
ER (season 4) ER with the help of Carter's grandmother. Ross vies for a pediatric attending position in the ER. A lonely Corday starts a relationship with Benton, which causes friction with Benton's family because she is white. Weaver attends a Synergix seminar to see how to better manage the ER. She begins to date a Synergix representative, Ellis West, who advises her to fire a physician's assistant, which happens to be Jeanie Boulet. Jeanie fights for her job, claiming that she was fired because of her HIV status. Facing a lawsuit, Chief of Staff Donald Anspaugh decides to hire her back. Weaver