Mozart and smallpox the imperial family were successful, and led to greater public acceptance for the procedure. Smallpox struck the Mozart family again in the next generation: Nannerl's eldest son Leopold and two of her stepchildren caught the disease during an outbreak in the Salzburg area in 1787. All three children survived. In 1796, the discovery of vaccination—the use of the related cowpox virus to immunize against smallpox—by Edward Jenner revolutionized the ability of medicine to deal with smallpox. Vaccination reached Vienna around 1800, when yet another local epidemic created impetus for its adoption. One of the doctors trained in the Vienna campaign,
1775–82 North American smallpox epidemic to say that policies and programs sprung up around epidemics and quarantines, wherever they were needed in the moment. However, the scourge of smallpox prompted changes to be made that would impact the public health of America for years to come. Even today, there is much debate surrounding the use of vaccines. Many parents and caregivers worry about potentially negative side effects associated with the vaccination of infants and children; this is merely and echo of the reaction to the smallpox inoculation and eventual vaccine. At the time of its introduction, almost all were extremely wary of this new medical