Berkeley, Gloucestershire Berkeley, Gloucestershire Berkeley ( ) is a small town and parish in Gloucestershire, England. It lies in the Vale of Berkeley between the east bank of the River Severn and the M5 motorway, within the Stroud administrative district. The town is noted for Berkeley Castle, where the imprisoned Edward II was murdered, as well as the birthplace of the physician Edward Jenner, pioneer of the smallpox vaccine, the world's first vaccine. The parish also includes the village of Berkeley Heath, which runs along the A38 Bristol to Gloucester road and the adjacent B4066 towards Berkeley. Berkeley lies midway between Bristol
Baron Berkeley that the barony by writ was deemed, extraordinarily, to be in effect a feudal barony (or barony by tenure), dependent on the tenure of Berkeley Castle. Thus when William Berkeley, 1st Marquess of Berkeley, 2nd Baron Berkeley (1426–1492), "William the Waste-All", alienated Berkeley Castle to the king, he effectively disinherited his younger brother from the barony by writ. The heir apparent is his son the Hon. Thomas FitzHardinge Gueterbock (b. 1969) The Earldom of Berkeley, together with the Viscountcy Dursley, was separated from the barony in 1882, but the accession was not fully established. In 1942 both titles became extinct