Berkeley, Gloucestershire Berkeley, Gloucestershire Berkeley ( ) is a small town and parish in Gloucestershire, England. It lies in the Vale of Berkeley between the east bank of the River Severn and the M5 motorway, within the Stroud administrative district. The town is noted for Berkeley Castle, where the imprisoned Edward II was murdered, as well as the birthplace of the physician Edward Jenner, pioneer of the smallpox vaccine, the world's first vaccine. The parish also includes the village of Berkeley Heath, which runs along the A38 Bristol to Gloucester road and the adjacent B4066 towards Berkeley. Berkeley lies midway between Bristol
Berkeley Castle genealogy documentary television series "Who Do You Think You Are?", with American actress Courteney Cox looking into her ancestry. Cox learns that she is a 21-generation direct descendant of Thomas de Berkeley, 3rd Baron Berkeley and 22-generation descendant of de Berkeley’s father-in-law, Roger Mortimer, 1st Earl of March – also learning of their parts in the murder of King Edward II of England at Berkeley Castle in 1327. Two ships of the Royal Navy have been named "Berkeley Castle" after the castle, as has a Great Western locomotive. Berkeley Castle Berkeley Castle ( ; historically sometimes spelt "Berkley Castle" or