Desperate Housewives (season 4) receiving star billing. All eleven starring actors from the previous season returned for this season. The series is narrated by Brenda Strong, who portrays the deceased Mary Alice Young, as she observes from beyond the grave the lives of the Wisteria Lane residents and her former best friends. Teri Hatcher portrayed Susan Delfino, who is finally married after three seasons searching for a stable relationship. Felicity Huffman portrayed Lynette Scavo, who fights cancer during the first half of the season and deals with her step-daughter's behavior in the second half. Marcia Cross portrayed Bree Hodge, married for the second time
Desperate Housewives (season 4) Preston Scavo, Porter Scavo and Parker Scavo, Lynette's troublesome children. Rachel Fox was promoted to regular after guest starring in several episodes in the previous season as Kayla Huntington Scavo, Tom's mischievous daughter and the result of an affair he had before meeting Lynette. This season featured many established and new guest stars. Kathryn Joosten portrayed Karen McCluskey, one of the most prominent residents of Wisteria Lane, Richard Burgi appeared as Karl Mayer, Susan's ex-husband who is also married again, Pat Crawford Brown played elderly neighbor Ida Greenberg, whereas Tuc Watkins and Kevin Rahm made their debut in this season