Vaccination and religion Vaccination and religion Vaccination and religion have interrelations of varying kinds. Almost no religions object to vaccination, and some parents either fake religious adherence or invent fake religions to provide exemption. The influential Massachusetts preacher Cotton Mather was the first known person to attempt smallpox inoculation on a large scale, inoculating himself and over 200 members of his congregation with the help of a local doctor. While his view became standard, he also caused the first reaction against the practice. Rowland Hill (1744–1833) was a popular English preacher acquainted with Edward Jenner, the pioneer of smallpox vaccination, and he encouraged
Smallpox scar. The antibodies induced by vaccinia vaccine are cross-protective for other orthopoxviruses, such as monkeypox, cowpox, and variola (smallpox) viruses. Neutralizing antibodies are detectable 10 days after first-time vaccination, and seven days after revaccination. Historically, the vaccine has been effective in preventing smallpox infection in 95 percent of those vaccinated. Smallpox vaccination provides a high level of immunity for three to five years and decreasing immunity thereafter. If a person is vaccinated again later, immunity lasts even longer. Studies of smallpox cases in Europe in the 1950s and 1960s demonstrated that the fatality rate among persons vaccinated less than 10