Desperate Housewives (season 4) receiving star billing. All eleven starring actors from the previous season returned for this season. The series is narrated by Brenda Strong, who portrays the deceased Mary Alice Young, as she observes from beyond the grave the lives of the Wisteria Lane residents and her former best friends. Teri Hatcher portrayed Susan Delfino, who is finally married after three seasons searching for a stable relationship. Felicity Huffman portrayed Lynette Scavo, who fights cancer during the first half of the season and deals with her step-daughter's behavior in the second half. Marcia Cross portrayed Bree Hodge, married for the second time
It Takes Two (Desperate Housewives) Monique", which means "I miss you, Monique" in French, revealing that it's a woman named Monique and Orson knew her. Although credited, Andrew Van De Kamp (Shawn Pyfrom), Preston Scavo (Brent Kinsman), Porter Scavo (Shane Kinsman), and Parker Scavo (Zane Huett) do not appear in this episode. Josh Henderson joins the cast as Austin McCann. It Takes Two (Desperate Housewives) "It Takes Two" is the 49th episode of the ABC television series, "Desperate Housewives". It was also the second episode of the show's third season. The episode was written by Kevin Murphy and Jenna Bans and directed by David Grossman.