Single-handed sailing circumnavigation, as it was contained within the southern hemisphere; however, he made the first single-handed passage of the three great capes, and indeed the first successful single-handed passage of Cape Horn. With only three landfalls, Vito Dumas described the legs of his trip as the longest that had been made by a single-hander, and in the most ferocious oceans on the Earth. Organised single-handed yacht racing was pioneered by Britons "Blondie" Hasler and Francis Chichester, who conceived the idea of a single-handed race across the Atlantic Ocean. This was a revolutionary concept at the time, as the idea was thought
Single-use bioreactor public forums it is a major backer of single use technology in general, as the technology provides significant benefits and value, including mitigation of cross contamination and reduced industry costs. The FDA has stated it will not issue guidance to the industry on single use but "may" issue Q and As on its web site. When an FDA approved single use production site is approved, the gates will open for broader and faster single use adoption worldwide. Already single use has shown itself to be a huge cost saver and to increase process flexibility and operational efficiency for biosimilar applications