Berkeley, Gloucestershire Berkeley, Gloucestershire Berkeley ( ) is a small town and parish in Gloucestershire, England. It lies in the Vale of Berkeley between the east bank of the River Severn and the M5 motorway, within the Stroud administrative district. The town is noted for Berkeley Castle, where the imprisoned Edward II was murdered, as well as the birthplace of the physician Edward Jenner, pioneer of the smallpox vaccine, the world's first vaccine. The parish also includes the village of Berkeley Heath, which runs along the A38 Bristol to Gloucester road and the adjacent B4066 towards Berkeley. Berkeley lies midway between Bristol
Berkeley Castle from the Minstrels' gallery. His tomb is in St Mary's churchyard which stands besides the castle. Adjoining the Great Hall was the Chapel of St Mary (now the morning room) with its painted wooden vaulted ceilings and a biblical passage, written in Norman French. In the late 16th century Queen Elizabeth I visited the castle and played bowls on the bowling green. During the English Civil War, the castle still held sufficient significance for it to be captured in 1645 by Colonel Thomas Rainsborough, for the Parliamentarian side and after a siege which saw cannon being fired at point blank