Vaccination disease people tried to prevent by inoculation and was the first disease for which a vaccine was produced. The smallpox vaccine was invented in 1796 by English physician Edward Jenner and although at least six people had used the same principles years earlier he was the first to publish evidence that it was effective and to provide advice on its production. Louis Pasteur furthered the concept through his work in microbiology. The immunization was called "vaccination" because it was derived from a virus affecting cows ( 'cow'). Smallpox was a contagious and deadly disease, causing the deaths of 20–60% of
1775–82 North American smallpox epidemic to say that policies and programs sprung up around epidemics and quarantines, wherever they were needed in the moment. However, the scourge of smallpox prompted changes to be made that would impact the public health of America for years to come. Even today, there is much debate surrounding the use of vaccines. Many parents and caregivers worry about potentially negative side effects associated with the vaccination of infants and children; this is merely and echo of the reaction to the smallpox inoculation and eventual vaccine. At the time of its introduction, almost all were extremely wary of this new medical