Mozart and smallpox the imperial family were successful, and led to greater public acceptance for the procedure. Smallpox struck the Mozart family again in the next generation: Nannerl's eldest son Leopold and two of her stepchildren caught the disease during an outbreak in the Salzburg area in 1787. All three children survived. In 1796, the discovery of vaccination—the use of the related cowpox virus to immunize against smallpox—by Edward Jenner revolutionized the ability of medicine to deal with smallpox. Vaccination reached Vienna around 1800, when yet another local epidemic created impetus for its adoption. One of the doctors trained in the Vienna campaign,
Smallpox vaccine in Koltsovo, Russia. These states report that their repositories are for possible antibioweaponry research and insurance if some obscure reservoir of natural smallpox is discovered in the future. The word "vaccine" is derived from "Variolae vaccinae" (i.e. smallpox of the cow), the term devised by Jenner to denote cowpox and used in the long title of his "An enquiry into the causes and effects of Variolae vaccinae, known by the name of cow pox". Vaccination, the term which soon replaced "cowpox inoculation" and "vaccine inoculation", was first used in print by Jenner's friend, Richard Dunning in 1800. Initially, the terms