Smallpox 1718. In 1721, Cotton Mather and colleagues provoked controversy in Boston by inoculating hundreds. In 1796, Edward Jenner, a doctor in Berkeley, Gloucestershire, rural England, discovered that immunity to smallpox could be produced by inoculating a person with material from a cowpox lesion. Cowpox is a poxvirus in the same family as variola. Jenner called the material used for inoculation vaccine, from the root word "vacca", which is Latin for cow. The procedure was much safer than variolation, and did not involve a risk of smallpox transmission. Vaccination to prevent smallpox was soon practiced all over the world. During the
Vaccination and religion removing religious exemptions at the same time as the only religion to apply for an exemption (Church of Christ Science) deemed their exemption to no longer be relevant. Vaccination and religion Vaccination and religion have interrelations of varying kinds. Almost no religions object to vaccination, and some parents either fake religious adherence or invent fake religions to provide exemption. The influential Massachusetts preacher Cotton Mather was the first known person to attempt smallpox inoculation on a large scale, inoculating himself and over 200 members of his congregation with the help of a local doctor. While his view became standard, he