Vaccination disease people tried to prevent by inoculation and was the first disease for which a vaccine was produced. The smallpox vaccine was invented in 1796 by English physician Edward Jenner and although at least six people had used the same principles years earlier he was the first to publish evidence that it was effective and to provide advice on its production. Louis Pasteur furthered the concept through his work in microbiology. The immunization was called "vaccination" because it was derived from a virus affecting cows ( 'cow'). Smallpox was a contagious and deadly disease, causing the deaths of 20–60% of
Vaccination policy immunity against it. This protects those unable to get the vaccine due to medical conditions, such as immune disorders. Vaccine-preventable diseases remain the most common cause of childhood mortality with an estimated three million deaths each year. Each year, vaccination prevents between two and three million deaths worldwide, across all age groups, from diphtheria, tetanus, pertussis and measles. With some vaccines, a goal of vaccination policies is to eradicate the disease – make it disappear from Earth altogether. The World Health Organization coordinated the effort to eradicate smallpox globally through vaccination, the last naturally occurring case of smallpox was in