The Big Sleep The Big Sleep The Big Sleep (1939) is a hardboiled crime novel by Raymond Chandler, the first to feature the detective Philip Marlowe. It has been adapted for film twice, in 1946 and again in 1978. The story is set in Los Angeles. The story is noted for its complexity, with characters double-crossing one another and secrets being exposed throughout the narrative. The title is a euphemism for death; it refers to a rumination about "sleeping the big sleep" in the final pages of the book. In 1999, the book was voted 96th of "Le Monde"s "100 Books of the
Sleep medicine by pathophysiologic mechanism, as far as possible, rather than by primary complaint. Training in sleep medicine is multidisciplinary, and the present structure was chosen to encourage a multidisciplinary approach to diagnosis. Sleep disorders often do not fit neatly into traditional classification; differential diagnoses cross medical systems. Minor revisions and updates to the ICSD were made in 1997 and in following years. The present classification system in fact follows the groupings suggested by Nathaniel Kleitman, the "father of sleep research," in his seminal 1939 book "Sleep and Wakefulness". The revised ICSD, ICSD-R, placed the primary sleep disorders in the subgroups (1)