Berkeley, Gloucestershire Berkeley, Gloucestershire Berkeley ( ) is a small town and parish in Gloucestershire, England. It lies in the Vale of Berkeley between the east bank of the River Severn and the M5 motorway, within the Stroud administrative district. The town is noted for Berkeley Castle, where the imprisoned Edward II was murdered, as well as the birthplace of the physician Edward Jenner, pioneer of the smallpox vaccine, the world's first vaccine. The parish also includes the village of Berkeley Heath, which runs along the A38 Bristol to Gloucester road and the adjacent B4066 towards Berkeley. Berkeley lies midway between Bristol
Monmouth Castle windows were installed in the upper part of the Great Tower which also had a new roof. As a town developed around the castle, the castle's defences were augmented by a town wall and fortified bridge, built at the end of the 13th century. Edward II briefly was held prisoner in the castle before he was transferred to Berkeley Castle where he died. The castle was a favourite residence of Henry Bolingbroke, later King as Henry IV. It was here that in 1387 the future King Henry V of England was born, to Bolingbroke's first wife Mary de Bohun. The