Berkeley, Gloucestershire Berkeley, Gloucestershire Berkeley ( ) is a small town and parish in Gloucestershire, England. It lies in the Vale of Berkeley between the east bank of the River Severn and the M5 motorway, within the Stroud administrative district. The town is noted for Berkeley Castle, where the imprisoned Edward II was murdered, as well as the birthplace of the physician Edward Jenner, pioneer of the smallpox vaccine, the world's first vaccine. The parish also includes the village of Berkeley Heath, which runs along the A38 Bristol to Gloucester road and the adjacent B4066 towards Berkeley. Berkeley lies midway between Bristol
Edward II of England move was highly unpopular. Isabella and Mortimer both amassed, and spent, great wealth, and criticism of them mounted. Relations between Mortimer and the young Edward III became strained and in 1330 the King conducted a "coup d'état" at Nottingham Castle. He arrested Mortimer and then executed him on fourteen charges of treason, including the murder of Edward II. Edward III's government sought to blame Mortimer for all of the recent problems, effectively politically rehabilitating the late King. The King spared Isabella, giving her a generous allowance, and she soon returned to public life. Edward's body was embalmed at Berkeley Castle,