Daniel Tupou his Tongan international debut against Scotland on the wing in the 26-24 loss at Derwent Park. Tupou played in all of Tonga's 3 matches in the tournament. On 4 May, Tupou was selected played for NSW City in the City vs Country Origin match in Dubbo, New South Wales. He played on the wing and scored 2 tries in the 26-all draw. Tupou was selected to make his debut for the New South Wales Blues in Game 1 of the 2014 State of Origin series on the wing in the 100th State of Origin match in the Blues 12-8 win
Christian Tupou agent in 2012. Tupou received his first NFL start in the preseason against the Cleveland Browns and recorded a sack. He was released in 2013. Tupou was signed to the practice squad on January 3, 2014. Tupou was signed to 49ers roster on January 22, 2014. Tupou was released by the 49ers to make room for Josh Johnson on May 14, 2014. Tupou signed with the Arizona Cardinals in May 2014. The Cardinals released Tupou on August 30, 2014, but he shortly re-signed to their practice squad. Tupou was signed to the Cleveland Browns practice squad on October 17, 2014.