Berkeley, Gloucestershire Berkeley, Gloucestershire Berkeley ( ) is a small town and parish in Gloucestershire, England. It lies in the Vale of Berkeley between the east bank of the River Severn and the M5 motorway, within the Stroud administrative district. The town is noted for Berkeley Castle, where the imprisoned Edward II was murdered, as well as the birthplace of the physician Edward Jenner, pioneer of the smallpox vaccine, the world's first vaccine. The parish also includes the village of Berkeley Heath, which runs along the A38 Bristol to Gloucester road and the adjacent B4066 towards Berkeley. Berkeley lies midway between Bristol
Joan de Geneville, 2nd Baroness Geneville worse privations having been locked up inside various religious houses with even less money at their disposal. Joan was transferred from Skipton to Pontefract Castle in July 1326. Mortimer and Isabella landed in England two months later in September 1326, and they joined forces with Henry, 3rd Earl of Lancaster. On 16 November, King Edward was taken prisoner and eventually murdered at Berkeley Castle, presumably by Mortimer's hired assassins. From 1327 to 1330, Mortimer and Isabella jointly held the Office of Regent for her son, King Edward III who was duly crowned following his father's death. Mortimer was made constable