Desperate Housewives of their late friend and neighbor who committed suicide in the pilot episode. The storyline covers thirteen years of the women's lives over eight seasons, set between the years 2004–2008, and later 2013–2017 (the storyline includes a five-year passage of time, as well as flashbacks and flashforwards ranging from the 1980s to the 2020s). They work through domestic struggles and family life, while facing the secrets, crimes, and mysteries hidden behind the doors of their—on the surface—beautiful and seemingly perfect suburban neighborhood. The series features an ensemble cast, headed by Teri Hatcher as Susan Mayer, Felicity Huffman as Lynette Scavo,
I Guess This Is Goodbye (Desperate Housewives) I Guess This Is Goodbye (Desperate Housewives) "I Guess This is Goodbye" is the 134th episode of the ABC television series, "Desperate Housewives". It is the twenty-third and the season finale episode of the show's sixth season and aired on May 16, 2010. The show opens with Mary Alice narrating over the hostage scene at Eddie's house: while Eddie panics, all Lynette can think about is her children. Lynette offers to give evidence for Eddie, and tell the police what a horrible woman his mother was, but Eddie confesses that his mother was not the only person he has killed.