Members of the western concert flute family Members of the western concert flute family The western concert flute family has a wide range of instruments. The piccolo is the highest-pitched member of the flute family, with a range an octave above that of the concert flute. It is usually the highest-pitched instrument within orchestras and bands. The piccolo has a stereotype for being difficult to play in tune; its small size makes it difficult to construct an evenly tuned scale. The treble flute is pitched in the key of G, a fifth above the concert flute. The instrument is rare today, only occasionally found in flute choirs
Kinesin family member 11 a requisite for diagnosis; 31% (16 out of 52) were de novo cases. All inherited cases, and 50% of sporadic cases of MCLMR are due to germline KIF11 mutations. Kinesin family member 11 Kinesin-5 is a molecular motor protein that is essential in mitosis. Kinesin-5 proteins are members of kinesin superfamily, which are nanomotors that move along microtubule tracks in the cell. Named from studies in the early days of discovery, it is also known as kinesin family member 11, encoded by the KIF11 gene, or as BimC, Eg5 or N-2, based on the founding members of this kinesin family.