Single-handed sailing circumnavigation, as it was contained within the southern hemisphere; however, he made the first single-handed passage of the three great capes, and indeed the first successful single-handed passage of Cape Horn. With only three landfalls, Vito Dumas described the legs of his trip as the longest that had been made by a single-hander, and in the most ferocious oceans on the Earth. Organised single-handed yacht racing was pioneered by Britons "Blondie" Hasler and Francis Chichester, who conceived the idea of a single-handed race across the Atlantic Ocean. This was a revolutionary concept at the time, as the idea was thought
Single-use bioreactor the pH, and the color, of the dye. The color change can be detected with a laser external to the bag. This and other methods of non-invasive measurement have been developed for single-use bioreactors. Single-use process steps available are: media and buffer preparation, cell harvesting, filtration, purification and virus inactivation. Other manufacturers include Cellexus with their CellMaker with an air lift system for bacterial production,PBS Biotech, Inc. with its novel Air-Wheel mixing mechanism and low shear and scalability from lab to cGMP (Good manufacturing practice) production and is fully integrated, easy to use www.pbsbiotech.com as well as Millipore, which is