Smallpox one-third of the cases resulted in blindness. These deaths included those of four reigning monarchs and a queen consort. In the 20th century smallpox killed 200-300 million people. Edward Jenner discovered in 1798 that vaccination could prevent smallpox. In 1967, the WHO intensified efforts to eliminate the disease. Smallpox is one of two infectious diseases to have been eradicated, the other being rinderpest in 2011. The term "smallpox" was first used in Britain in the 15th century to distinguish the disease from syphilis, which was then known as the "great pox". Other historical names for the disease include pox, speckled
Vaccination and religion out these procedures be tried for attempted murder. In 1816 Iceland made the clergy responsible for smallpox vaccination and gave them the responsibility of keeping vaccination records for their parishes; Sweden also had similar practices. When vaccination was introduced into UK public policy, and adoption followed overseas, there was opposition from trade unionists and others, including sectarian ministers and those interested in self-help and alternative medicines like homeopathy. Anti-vaccinationists were most common in Protestant countries. Those who were religious often came from minority religious movements outside of mainstream Protestantism, including Quakers in England and Baptists in Sweden. Catholic and Anglican