Berkeley, Gloucestershire Berkeley, Gloucestershire Berkeley ( ) is a small town and parish in Gloucestershire, England. It lies in the Vale of Berkeley between the east bank of the River Severn and the M5 motorway, within the Stroud administrative district. The town is noted for Berkeley Castle, where the imprisoned Edward II was murdered, as well as the birthplace of the physician Edward Jenner, pioneer of the smallpox vaccine, the world's first vaccine. The parish also includes the village of Berkeley Heath, which runs along the A38 Bristol to Gloucester road and the adjacent B4066 towards Berkeley. Berkeley lies midway between Bristol
Edward II of England regime collapsed and he fled to Wales, where he was captured in November. The king was forced to relinquish his crown in January 1327 in favour of his 14-year-old son, Edward III, and he died in Berkeley Castle on 21 September, probably murdered on the orders of the new regime. Edward's relationship with Gaveston inspired Christopher Marlowe's 1592 play "Edward II", along with other plays, films, novels and media. Many of these have focused on the possible sexual relationship between the two men. Edward's contemporaries criticised his performance as king, noting his failures in Scotland and the oppressive regime of