A Single Girl her a César Award nomination. A Single Girl A Single Girl () is a 1995 French drama film directed by Benoît Jacquot. It follows a day in the life of a young Parisian woman named Valérie (played by Virginie Ledoyen) who begins a new job at a four star hotel the same day she reveals to her boyfriend that she is pregnant. The 90 minute film is shot in real time, with a very mobile camera style, recalling the French New Wave. This was the breakthrough role for the 19-year-old Ledoyen (who later became known in America for the 2000
Single-use bioreactor validation procedures can be made easier, and will finally lead to significant cost reductions. The application of single-use bioreactors reduces the risk of cross contamination and enhances the biological and process safety. Single-use applications are especially suitable for any kind of biopharmaceutical product. Single-use bioreactors contain fewer parts compared with conventional bioreactors, so the initial and maintenance costs are reduced. Limiting factor for the use of "some" single-use bioreactors is the achievable oxygen transfer, represented by the specific mass transfer coefficient (k) for the specific phase area (a), resulting in the volumetric oxygen mass transfer coefficient (ka). Theoretically this can