Single-handed sailing circumnavigation, as it was contained within the southern hemisphere; however, he made the first single-handed passage of the three great capes, and indeed the first successful single-handed passage of Cape Horn. With only three landfalls, Vito Dumas described the legs of his trip as the longest that had been made by a single-hander, and in the most ferocious oceans on the Earth. Organised single-handed yacht racing was pioneered by Britons "Blondie" Hasler and Francis Chichester, who conceived the idea of a single-handed race across the Atlantic Ocean. This was a revolutionary concept at the time, as the idea was thought
Single-use bioreactor and for biotech startups and CROs. Emerging markets are expected to embrace single use vs stainless given their lack of legacy infrastructure and desire to drive capex and opex costs out of the biotech operation. The market today is approx. $200M and could grow to over $1B or more in the next 4–5 years. Compared with conventional bioreactor systems, the single-use solution has some advantages. Application of single-use technologies reduces cleaning and sterilization demands. Some estimates show cost savings of more than 60% with single use systems compared to fixed asset stainless steel bioreactors. In pharmaceutical production, complex qualification and