Vaccination and religion Vaccination and religion Vaccination and religion have interrelations of varying kinds. Almost no religions object to vaccination, and some parents either fake religious adherence or invent fake religions to provide exemption. The influential Massachusetts preacher Cotton Mather was the first known person to attempt smallpox inoculation on a large scale, inoculating himself and over 200 members of his congregation with the help of a local doctor. While his view became standard, he also caused the first reaction against the practice. Rowland Hill (1744–1833) was a popular English preacher acquainted with Edward Jenner, the pioneer of smallpox vaccination, and he encouraged
Smallpox short duration of the infectious stage. In temperate areas, the number of smallpox infections was highest during the winter and spring. In tropical areas, seasonal variation was less evident and the disease was present throughout the year. Age distribution of smallpox infections depended on acquired immunity. Vaccination immunity declined over time and was probably lost within thirty years. Smallpox was not known to be transmitted by insects or animals and there was no asymptomatic carrier state. The clinical definition of smallpox is an illness with acute onset of fever equal to or greater than followed by a rash characterized by