Anthony Tupou the 2008 Rugby League World Cup. He was named in the Australia squad for the 2008 Rugby League World Cup, replacing Michael Crocker who withdrew through injury. Although also named in the Tonga training squad for the 2008 Rugby League World Cup, Tupou played for Australia. Tupou played for the Sharks mainly at second-row forward. Tupou was named in NSW's preliminary 40 man squad for the 2009 State of Origin series. He was selected for Country in the City vs Country match on 8 May 2009. In 2013, Tupou played for the Tonga national rugby league team in their Pacific
Anthony Tupou September 2004 issue of "Big League" magazine, after making his début with the Roosters, Tupou claimed that growing up his favourite player to watch was Queensland legend Mal Meninga. He also claimed that the biggest influence on his football was his father and his club coach Ricky Stuart. At the end of that season he played for the Roosters from the interchange bench in their 2004 NRL grand final loss to cross-Sydney rivals, the Bulldogs. In 2005, Tupou made his representative début in the City vs Country Origin for the Country NSW team. At the end of the 2006 season,