Multiple electrode aggregometry and ADP-receptors. Adding ASA (acetylsalicylic acid) reagent to a blood sample reduces the aggregation responses in ASPItest and COLtest. ASA irreversibly inhibits COX1 in platelets, thereby inhibiting the production of TXA2. The ASA Reagent is used as a quality control in the platelet function testing with Multiplate, allowing the assessment of abnormal platelet responses in ASPItest and COLtest. This reagent is used as a quality control in Multiplate platelet function testing. The GPIIb/IIIa antagonist blocks the binding of fibrinogen to the GPIIb/IIIa receptors, preventing the formation of platelet-fibrinogen bonds and resulting in significantly reduced platelet aggregation in response to all
Asa Townsend Asa Townsend Asa Townsend (c.1775-alive 1851) was an early settler in Westminster Township near what became the City of London, Ontario. His lands ultimately became incorporated in London's Springbank Park. By the 1820s he removed westward to settle on the bank of the Ausable River in what later became Bosanquet Township in Lambton County. Here he operated a salt well. He and his wife—whose name is not known—are credited with being the first white settlers in the area of the present village of Arkona, Ontario. Asa was still living at the time of the 1851 Bosanquet Township assessment, living just