Growth hormone secretagogue receptor Growth hormone secretagogue receptor Growth hormone secretagogue receptor(GHS-R), also known as ghrelin receptor, is a G protein-coupled receptor that binds growth hormone secretagogues (GHSs), such as ghrelin, the "hunger hormone". The role of GHS-R is thought to be in regulating energy homeostasis and body weight. In the brain, they are most highly expressed in the hypothalamus, specifically the ventromedial nucleus and arcuate nucleus. GSH-Rs are also expressed in other areas of the brain, including the ventral tegmental area, hippocampus, and substantia nigra. Outside the central nervous system, too, GSH-Rs are also found in the liver, in skeletal muscle, and even
Doctor Hormone to aid in their nation's wars against its neighbors, Doctor Hormone and his granddaughter Jane traveled to the besieged nation of Novoslavia, where he used his scientific expertise to help battle the Urasian invaders, who were using the hormones to create armies of part animal/part human men. Later, Doctor Hormone was employed as a researcher for the United States Army and worked in a laboratory at Fort Knox. Doctor Hormone was later summoned by a disembodied voice called The Thinker who temporarily endowed him with superhuman powers to fight off an invasion of Texas by the Nazians. Then, The Thinker