Adult-onset Still's disease Adult-onset Still's disease Adult-onset Still's disease (AOSD) is a form of Still's disease, a rare systemic autoinflammatory disease characterized by the classic triad of persistent high spiking fevers, joint pain, and a distinctive salmon-colored bumpy rash. The disease is considered a diagnosis of exclusion. Levels of the iron-binding protein ferritin may be extremely elevated with this disorder. AOSD may present in a similar manner to other inflammatory diseases and to autoimmune diseases, which must be ruled out before making the diagnosis. Prognosis is usually favorable but manifestations of the disease affecting the lungs, heart, or kidneys may occasionally cause severe
Citrus leprosis disease In fruits, dark and depressed lesions are found in large numbers and affecting only the external part. Commercial losses result from undesirable appearance and fruits falling. Some differences in symptoms produced by CiLV-C and CiLV-N have been reported; in leaves and fruits, lesions caused by the nuclear type are smaller and more numerous than those caused by the cytoplasmic type. Lesions caused by CiLV-C shows additional halos, making them look larger. This disease is considered an important problem in citriculture in countries where it has been established, and is considered the major viral disease in citrus in Brazil. Damage by