Byssinosis not brown. Brown lung can ultimately result in narrowing of the airways, lung scarring and death from infection or respiratory failure. Patient history should reveal exposure to cotton, flax, hemp, or jute dust. Diagnostic tests include a lung function test and a chest x ray or CT scan. Measurable change in lung function before and after working shifts is key to diagnosis. Patients suffering from byssinosis show a significant drop in FEV1 over the course of work shift. Chest radiographs show areas of opacity due to fibrosis of the pulmonary parenchyma. Affected workers should be offered alternative employment. Continued exposure
Adult polyglucosan body disease Adult polyglucosan body disease Adult polyglucosan body disease (APBD) is an orphan disease and a glycogen storage disorder that is caused by an inborn error of metabolism. Symptoms can emerge any time after the age of 30; early symptoms include trouble controlling urination, trouble walking, and lack of sensation in the legs. People eventually develop dementia. A person inherits loss-of-function mutations in the "GBE1" gene from each parent, and the lack of glycogen branching enzyme (the protein encoded by "GNE1") leads to buildup of unbranched glycogen in cells, which harms neurons more than other kinds of cells. Most people first