Panama disease Panama disease Panama disease is a plant disease of the roots of banana plants. It is a type of fusarium wilt, caused by the fungal pathogen "Fusarium oxysporum" f. sp." cubense" (Foc). The pathogen is resistant to fungicide and cannot be controlled chemically. During the 1950s, Panama disease wiped out most commercial Gros Michel banana production. The Gros Michel banana was the dominant cultivar of bananas, and the blight inflicted enormous costs and forced producers to switch to other, disease-resistant cultivars. New strains of Panama disease currently threaten the production of today's most popular cultivar, Cavendish. Two external symptoms help
Sandhoff disease Sandhoff disease have similar symptoms but to a lesser extent. Adult and juvenile forms of Sandhoff disease are more rare than the infantile form. In these cases victims suffer cognitive impairment (retardation) and a loss of muscle coordination that impairs and eventually destroys their ability to walk; the characteristic red spots in the retina also develop. The adult form of the disease, however, is sometimes milder, and may only lead to muscle weakness that impairs walking or the ability to get out of bed. Two parents carrying a mutated gene and passing it on to their offspring cause the disease.