Growth hormone secretagogue receptor Growth hormone secretagogue receptor Growth hormone secretagogue receptor(GHS-R), also known as ghrelin receptor, is a G protein-coupled receptor that binds growth hormone secretagogues (GHSs), such as ghrelin, the "hunger hormone". The role of GHS-R is thought to be in regulating energy homeostasis and body weight. In the brain, they are most highly expressed in the hypothalamus, specifically the ventromedial nucleus and arcuate nucleus. GSH-Rs are also expressed in other areas of the brain, including the ventral tegmental area, hippocampus, and substantia nigra. Outside the central nervous system, too, GSH-Rs are also found in the liver, in skeletal muscle, and even
Maximum the Hormone suffering a herniated disc. Maximum the Hormone performs nu metal and hardcore punk but incorporates many elements of pop, funk, ska, hip hop and extreme metal into their music as well which helps to distinguish them from many typical nu metal and hardcore punk bands. The band is also labeled as alternative metal, funk metal, groove metal and more recently metalcore by some critics. AllMusic's Alexey Eremenko writes that Maximum the Hormone is distinguished by "a general lack of the teenage angst and self-importance characteristic of true nu-metalers". Their funky sound, heard in many songs such as "Maximum 21st Century",