Willow active extract of the bark, called salicin, was isolated to its crystalline form in 1828 by Henri Leroux, a French pharmacist, and Raffaele Piria, an Italian chemist, who then succeeded in separating out the compound in its pure state. In 1897, Felix Hoffmann created a synthetically altered version of salicin (in his case derived from the "Spiraea" plant), which caused less digestive upset than pure salicylic acid. The new drug, formally acetylsalicylic acid, was named Aspirin by Hoffmann's employer Bayer AG. This gave rise to the hugely important class of drugs known as nonsteroidal anti-inflammatory drugs (NSAIDs). Some of humans'
Hippocrates (lunar crater) number of tiny craterlets, and is slightly wider at the southern edge with a ridge-like projection. The interior floor is level and almost featureless, with only a few tiny craterlets to mark the surface. This crater was named after Hippocrates, the ancient Greek physician. By convention these features are identified on lunar maps by placing the letter on the side of the crater midpoint that is closest to Hippocrates. Hippocrates (lunar crater) Hippocrates is a lunar impact crater on the far side of the Moon. It is located in the northern region of the lunar surface, to the north of