Multiple electrode aggregometry and ADP-receptors. Adding ASA (acetylsalicylic acid) reagent to a blood sample reduces the aggregation responses in ASPItest and COLtest. ASA irreversibly inhibits COX1 in platelets, thereby inhibiting the production of TXA2. The ASA Reagent is used as a quality control in the platelet function testing with Multiplate, allowing the assessment of abnormal platelet responses in ASPItest and COLtest. This reagent is used as a quality control in Multiplate platelet function testing. The GPIIb/IIIa antagonist blocks the binding of fibrinogen to the GPIIb/IIIa receptors, preventing the formation of platelet-fibrinogen bonds and resulting in significantly reduced platelet aggregation in response to all
Asa C. Matthews Asa C. Matthews Asa Carrington Matthews (March 22, 1833 – June 14, 1908) was an American lawyer, judge, and politician. Born in Pike County, Illinois, Matthews went to the public schools. He went to McKendree College and Illinois College. In 1857, Matthew was admitted to the Illinois bar. During the American Civil War, Matthew served in the 99th Illinois Volunteer Infantry Regiment. He then practiced law in Pittsfield, Illinois. Matthews was elected to the Illinois House of Representatives and served as the speaker. Matthews was a Republican. He also was appointed Illinois Circuit Court judge in 1885. Matthews also served