Acetyl group known as paracetamol), and acetylsalicylic acid (better known as aspirin). The introduction of an acetyl group into a molecule is called acetylation. In biological organisms, acetyl groups are commonly transferred from acetyl-CoA to other organic molecules. Acetyl-CoA is an intermediate both in the biological synthesis and in the breakdown of many organic molecules. Acetyl-CoA is also created during the second stage of cellular respiration, the Krebs Cycle, by the action of pyruvate dehydrogenase on pyruvic acid. Histones and other proteins are often modified by acetylation. For example, on the DNA level, histone acetylation by acetyltransferases (HATs) causes an expansion of
Willow flute tempered scale. Modern willow flutes are typically made of plastic (PVC tubing is often used), but the original willow flutes were made from sections of bark cut from green willow branches. Willow flutes could only be made this way during the spring, and became unplayable when the bark dried out. Noted modern willow flute artists include the group Hedningarna and Anders Norudde of Sweden. Other Scandinavian groups that use the Seljefløyte in traditional arrangements include Eivind Groven, Steinar Ofsdal, Groupa and Bask. There is also a Karelian variant of the willow flute that is made in Finnish Karelia and the