Willow bark of the willow tree have been mentioned in ancient texts from Assyria, Sumer and Egypt as a remedy for aches and fever, and in Ancient Greece the physician Hippocrates wrote about its medicinal properties in the fifth century BC. Native Americans across the Americas relied on it as a staple of their medical treatments. It provides temporary pain relief. Salicin is metabolized into salicylic acid in the human body, and is a precursor of aspirin. In 1763, its medicinal properties were observed by the Reverend Edward Stone in England. He notified the Royal Society, which published his findings. The
Salix alba from the wood was important for gunpowder manufacture. The bark tannin was used in the past for tanning leather. The wood is used to make cricket bats. "S. alba" wood has a low density and a lower transverse compressive strength. This allows the wood to bend, which is why it can be used to make baskets. Willow bark contains Indole-3-butyric acid, which is a plant hormone stimulating root growth; willow trimmings are sometimes used to clone rootstock in place of commercially synthesized root stimulator. It is also used for ritual purposes by Jews on the holiday of Sukkot. Hippocrates, Galen,