Acetyl group known as paracetamol), and acetylsalicylic acid (better known as aspirin). The introduction of an acetyl group into a molecule is called acetylation. In biological organisms, acetyl groups are commonly transferred from acetyl-CoA to other organic molecules. Acetyl-CoA is an intermediate both in the biological synthesis and in the breakdown of many organic molecules. Acetyl-CoA is also created during the second stage of cellular respiration, the Krebs Cycle, by the action of pyruvate dehydrogenase on pyruvic acid. Histones and other proteins are often modified by acetylation. For example, on the DNA level, histone acetylation by acetyltransferases (HATs) causes an expansion of
Willow Bunch, Saskatchewan Willow Bunch community, settled in what is part of the present-day Jean Louis Légaré Regional Park. Légaré, who married into the Métis community, opened a trading post/store there, and often traded various necessities to the local Métis for bison goods. In the spring of 1881, it was estimated he had around $3,000 worth of bison products in his store. A boy named Édouard Beaupré, better known as the Willow Bunch Giant, was the first child born and baptized in the area in 1881. The forerunner settlement of Willow Bunch was established in 1883, around two miles east of Légaré's store