Past sea level has varied by somewhat more than a hundred metres. This is primarily due to the growth and decay of ice sheets (mostly in the northern hemisphere) with water evaporated from the sea. The Mediterranean Basin's gradual growth as the Neotethys basin, begun in the Jurassic, did not suddenly affect ocean levels. While the Mediterranean was forming during the past 100 million years, the average ocean level was generally 200 metres above current levels. However, the largest known example of marine flooding was when the Atlantic breached the Strait of Gibraltar at the end of the Messinian Salinity Crisis about 5.2
Hypothetical types of biochemistry too unstable at Earth temperatures to be useful. Ammonia could be a liquid at Earth-like temperatures, but at much higher pressures; for example, at 60 atm, ammonia melts at −77 °C (196 K) and boils at 98 °C (371 K). Ammonia and ammonia–water mixtures remain liquid at temperatures far below the freezing point of pure water, so such biochemistries might be well suited to planets and moons orbiting outside the water-based habitability zone. Such conditions could exist, for example, under the surface of Saturn's largest moon Titan. Methane (CH) is a simple hydrocarbon: that is, a compound of two of