Adult-onset Still's disease Adult-onset Still's disease Adult-onset Still's disease (AOSD) is a form of Still's disease, a rare systemic autoinflammatory disease characterized by the classic triad of persistent high spiking fevers, joint pain, and a distinctive salmon-colored bumpy rash. The disease is considered a diagnosis of exclusion. Levels of the iron-binding protein ferritin may be extremely elevated with this disorder. AOSD may present in a similar manner to other inflammatory diseases and to autoimmune diseases, which must be ruled out before making the diagnosis. Prognosis is usually favorable but manifestations of the disease affecting the lungs, heart, or kidneys may occasionally cause severe
Lewy body dementia with Parkinson's disease, and according to his widow he experienced depression, anxiety, and increasing paranoia. Upon autopsy his widow said he was found to have diffuse DLB. Ian G. McKeith, a dementia researcher and professor of old age psychiatry, commented that DLB was still too little known, and that Williams' symptoms were explained by DLB. The LBDA clarified the distinction between the term used in the autopsy report, "diffuse Lewy body dementia"—which is more commonly called "diffuse Lewy body disease" and refers to the underlying disease process—and the umbrella term, "Lewy body dementia," which encompasses both PDD and DLB. According