Adult-onset Still's disease Adult-onset Still's disease Adult-onset Still's disease (AOSD) is a form of Still's disease, a rare systemic autoinflammatory disease characterized by the classic triad of persistent high spiking fevers, joint pain, and a distinctive salmon-colored bumpy rash. The disease is considered a diagnosis of exclusion. Levels of the iron-binding protein ferritin may be extremely elevated with this disorder. AOSD may present in a similar manner to other inflammatory diseases and to autoimmune diseases, which must be ruled out before making the diagnosis. Prognosis is usually favorable but manifestations of the disease affecting the lungs, heart, or kidneys may occasionally cause severe
Citrus leprosis disease Citrus leprosis disease Citrus leprosis (CL) is an economically important viral disease affecting citrus crops. This emerging disease is widely distributed in South and Central America, from Argentina to Mexico. The disease is associated with up to three different non-systemic viruses, which cause similar symptoms in the citrus hosts and are transmitted by the same vector, mites of the genus "Brevipalpus"; although they have vastly different genomes. Citrus leprosis virus" nuclear type (CiLV-N) is found in the nuclei and cytoplasm of infected cells, while Citrus leprosis virus" cytoplasmic type (CiLV-C) is found in the endoplasmic reticulum. In 2012, a new