Crop diversity fruit trees and banana plants) are cloned. A single pest or disease could threaten a whole crop due to this uniformity ("genetic erosion"). A well-known historic case was the Irish Potato Famine of 1845-1847, where a vital crop with low diversity was destroyed by a single fungus. Another example is when a disease caused by a fungus affected the monocultured 1970 US corn crop, causing a loss of over one billion dollars in production. A danger to agriculture is wheat rust, a pathogenic fungus causing reddish patches, coloured by its spores. A virulent form of the wheat disease, stem rust,
Little cherry disease the fruit crop less hidden by the canopy, and leaf symptoms, varying from a slight marginal up-curl of the leaves to marked reddening of leaf surfaces. The general vigor of infected trees may be impaired, though this is not always apparent. Diagnosis of the disease can be assisted by RT-PCR assays. Other "Prunus" species may act as symptomless or tolerant carriers of the disease; especially cultivars of Japanese flowering cherry ("Prunus serrulata") have been implicated as such. There is no known cure for little cherry disease and tolerance breeding programs have not yielded any cultivars able to withstand the effects