Panama disease leaves and progresses to younger leaves until the entire plant dies. Gros Michel was the only type of banana eaten in the United States from the late 19th century until after World War II. From the beginning, however, a serious disease was present in the banana plantations of Central America. The problem was first diagnosed in Panama after which it was named. Over several decades, the fungus spread from Panama to neighboring countries, moving north through Costa Rica to Guatemala and south into Colombia and Ecuador. The banana industry was in a serious crisis, so a new banana thought to
Sandhoff disease Sandhoff disease have similar symptoms but to a lesser extent. Adult and juvenile forms of Sandhoff disease are more rare than the infantile form. In these cases victims suffer cognitive impairment (retardation) and a loss of muscle coordination that impairs and eventually destroys their ability to walk; the characteristic red spots in the retina also develop. The adult form of the disease, however, is sometimes milder, and may only lead to muscle weakness that impairs walking or the ability to get out of bed. Two parents carrying a mutated gene and passing it on to their offspring cause the disease.