Whipple's disease expert in the disease, applied novel diagnostic methods to stored tissue samples from Whipple's original patient, and demonstrated "T. whipplei" in these tissues. Whipple's disease Whipple's disease is a rare, systemic infectious disease caused by the bacterium "Tropheryma whipplei". First described by George Hoyt Whipple in 1907 and commonly considered a gastrointestinal disorder, Whipple's disease primarily causes malabsorption but may affect any part of the body including the heart, brain, joints, skin, lungs and the eyes. Weight loss, diarrhea, joint pain, and arthritis are common presenting symptoms, but the presentation can be highly variable and approximately 15% of patients do
Citrus leprosis disease In fruits, dark and depressed lesions are found in large numbers and affecting only the external part. Commercial losses result from undesirable appearance and fruits falling. Some differences in symptoms produced by CiLV-C and CiLV-N have been reported; in leaves and fruits, lesions caused by the nuclear type are smaller and more numerous than those caused by the cytoplasmic type. Lesions caused by CiLV-C shows additional halos, making them look larger. This disease is considered an important problem in citriculture in countries where it has been established, and is considered the major viral disease in citrus in Brazil. Damage by