Adult-onset Still's disease Adult-onset Still's disease Adult-onset Still's disease (AOSD) is a form of Still's disease, a rare systemic autoinflammatory disease characterized by the classic triad of persistent high spiking fevers, joint pain, and a distinctive salmon-colored bumpy rash. The disease is considered a diagnosis of exclusion. Levels of the iron-binding protein ferritin may be extremely elevated with this disorder. AOSD may present in a similar manner to other inflammatory diseases and to autoimmune diseases, which must be ruled out before making the diagnosis. Prognosis is usually favorable but manifestations of the disease affecting the lungs, heart, or kidneys may occasionally cause severe
Foreign animal disease serological, and molecular techniques. There is no vaccine available for this disease, and pharmaceutical therapy is not recommended because animals may improve clinically but will remain carriers. Good hygiene at assisted matings must be utilized. Compulsory notification and slaughter of infected horses is used to help control the disease, and most countries legislate control of movement. Foot-and-mouth disease Foot-and-mouth disease (FMD) is a severe highly contagious viral disease affecting cloven-hooved animals, such as cattle, sheep, and swine. FMD was once worldwide but has been largely controlled in developed nations, and has been eradicated from some regions such as North America