Adult-onset Still's disease Adult-onset Still's disease Adult-onset Still's disease (AOSD) is a form of Still's disease, a rare systemic autoinflammatory disease characterized by the classic triad of persistent high spiking fevers, joint pain, and a distinctive salmon-colored bumpy rash. The disease is considered a diagnosis of exclusion. Levels of the iron-binding protein ferritin may be extremely elevated with this disorder. AOSD may present in a similar manner to other inflammatory diseases and to autoimmune diseases, which must be ruled out before making the diagnosis. Prognosis is usually favorable but manifestations of the disease affecting the lungs, heart, or kidneys may occasionally cause severe
Citrus stubborn disease Citrus stubborn disease The Citrus stubborn disease is a plant disease affecting species in the genus "Citrus". "Spiroplasma citri", a Mollicute bacterium species, is the causative agent of the disease. It is present in the phloem of the affected plant and transmitted by several leafhoppers including "Circulifer tenellus" (beet leafhopper) and "Scaphytopius nitridus" in citrus-growing regions of California and Arizona and "Circulifer haematoceps" in the Mediterranean region. The host most notably affected is sweet orange but the bacterium can also infect weeds such as periwinkle ("Vinca rosea") and London rocket ("Sisymbrium irio"). Yellowed plants of Chinese cabbage and pak-choi ("Brassica