Multiple electrode aggregometry and ADP-receptors. Adding ASA (acetylsalicylic acid) reagent to a blood sample reduces the aggregation responses in ASPItest and COLtest. ASA irreversibly inhibits COX1 in platelets, thereby inhibiting the production of TXA2. The ASA Reagent is used as a quality control in the platelet function testing with Multiplate, allowing the assessment of abnormal platelet responses in ASPItest and COLtest. This reagent is used as a quality control in Multiplate platelet function testing. The GPIIb/IIIa antagonist blocks the binding of fibrinogen to the GPIIb/IIIa receptors, preventing the formation of platelet-fibrinogen bonds and resulting in significantly reduced platelet aggregation in response to all
Worse is better Rise of Worse is Better", Gabriel claimed that "Worse-is-Better" is a model of software design and implementation which has the following characteristics (in approximately descending order of importance): Gabriel argued that early Unix and C, developed by Bell Labs, are examples of this design approach. Gabriel contrasted his philosophy with what he called the "MIT/Stanford style of design" or "MIT approach" (also known as "the Right Thing"), which he described as follows. Contrasts are in bold: Gabriel argued that "Worse is better" produced more "successful" software than the MIT approach: As long as the initial program is basically good, it