Ghrelin capacity for food but also dramatically lowers ghrelin levels compared to both lean controls and those that lost weight through dieting alone. However, studies are conflicting as to whether or not ghrelin levels return to nearly normal with gastric bypass patients in the long term after weight loss has stabilized. Bariatric surgeries involving vertical-sleeve gastrectomy reduce plasma ghrelin levels by about 60% in the long term. Ghrelin plasma concentration increases with age and this may contribute to the tendency for weight gain as people age. Ghrelin Ghrelin (pronounced ), the "hunger hormone", also known as lenomorelin (INN), is a peptide
Transgender hormone therapy Transgender hormone therapy Transgender hormone therapy, also sometimes called cross-sex hormone therapy, is a form of hormone replacement therapy (HRT) in which sex hormones and other hormonal medications are administered to transgender or gender nonconforming individuals for the purpose of more closely aligning their secondary sexual characteristics with their gender identity. This form of HRT is given as one of two types, based on whether the goal of treatment is feminization or masculinization: Some intersex people may also undergo HRT, either starting in childhood to confirm the sex they were assigned at birth, or later in order to align their