Salicylic acid the OH group is "ortho" to the carboxyl group. It is also known as 2-hydroxybenzoic acid. It is poorly soluble in water (2 g/L at 20 °C). Aspirin (acetylsalicylic acid or ASA) can be prepared by the esterification of the phenolic hydroxyl group of salicylic acid with the acetyl group from acetic anhydride or acetyl chloride. Salicylic acid can also be prepared using the Kolbe-Schmitt reaction. Salicylic acid is used as a food preservative, a bactericidal and an antiseptic. Sodium salicylate is a useful phosphor in the vacuum ultraviolet spectral range, with nearly flat quantum efficiency for wavelengths between 10
Hippocrates of Chios Hippocrates of Chios Hippocrates of Chios (; c. 470 – c. 410 BC) was an ancient Greek mathematician, geometer, and astronomer. He was born on the isle of Chios, where he was originally a merchant. After some misadventures (he was robbed by either pirates or fraudulent customs officials) he went to Athens, possibly for litigation. There he became a leading mathematician. On Chios, Hippocrates may have been a pupil of the mathematician and astronomer Oenopides of Chios. In his mathematical work there probably was some Pythagorean influence too, perhaps via contacts between Chios and the neighbouring island of Samos, a