Growth hormone secretagogue receptor of selective ligands for the GHS-R receptor are now available and are being developed for several clinical applications. GHS-R agonists have appetite-stimulating and growth hormone-releasing effects, and are likely to be useful for the treatment of muscle wasting and frailty associated with old-age and degenerative diseases. On the other hand, GHS-R antagonists have anorectic effects and are likely to be useful for the treatment of obesity. Growth hormone secretagogue receptor Growth hormone secretagogue receptor(GHS-R), also known as ghrelin receptor, is a G protein-coupled receptor that binds growth hormone secretagogues (GHSs), such as ghrelin, the "hunger hormone". The role of GHS-R
Maximum the Hormone suffering a herniated disc. Maximum the Hormone performs nu metal and hardcore punk but incorporates many elements of pop, funk, ska, hip hop and extreme metal into their music as well which helps to distinguish them from many typical nu metal and hardcore punk bands. The band is also labeled as alternative metal, funk metal, groove metal and more recently metalcore by some critics. AllMusic's Alexey Eremenko writes that Maximum the Hormone is distinguished by "a general lack of the teenage angst and self-importance characteristic of true nu-metalers". Their funky sound, heard in many songs such as "Maximum 21st Century",