Multiple electrode aggregometry and ADP-receptors. Adding ASA (acetylsalicylic acid) reagent to a blood sample reduces the aggregation responses in ASPItest and COLtest. ASA irreversibly inhibits COX1 in platelets, thereby inhibiting the production of TXA2. The ASA Reagent is used as a quality control in the platelet function testing with Multiplate, allowing the assessment of abnormal platelet responses in ASPItest and COLtest. This reagent is used as a quality control in Multiplate platelet function testing. The GPIIb/IIIa antagonist blocks the binding of fibrinogen to the GPIIb/IIIa receptors, preventing the formation of platelet-fibrinogen bonds and resulting in significantly reduced platelet aggregation in response to all
Hippocrates the year 460 BC on the Greek island of Kos; other biographical information, however, is likely to be untrue. Soranus of Ephesus, a 2nd-century Greek physician, was Hippocrates' first biographer and is the source of most personal information about him. Later biographies are in the "Suda" of the 10th century AD, and in the works of John Tzetzes, Aristotle's "Politics", which date from the 4th century BC. Soranus wrote that Hippocrates' father was Heraclides, a physician, and his mother was Praxitela, daughter of Tizane. The two sons of Hippocrates, Thessalus and Draco, and his son-in-law, Polybus, were his students. According