Generic trademark acquired substantial market dominance or mind share, such that the primary meaning of the genericized trademark becomes the product or service itself rather than an indication of source for the product or service. A trademark thus popularized has its legal protection at risk in some countries such as the United States and United Kingdom, as its intellectual property rights in the trademark may be lost and competitors enabled to use the genericized trademark to describe their similar products, unless the owner of an affected trademark works sufficiently to correct and prevent such broad use. Thermos, Kleenex, ChapStick, Aspirin, Dumpster, Band-Aid,
Bernardino Ramazzini medicine and played a substantial role in its development. He proposed that physicians should extend the list of questions that Hippocrates recommended they ask their patients by adding, "What is your occupation?". Ramazzini saw prevention as being better than cure. In his Oratio given in 1711, he suggested that "it is much better to prevent than to cure, and so much easier to foresee future harm and avoid it rather than have to get rid of it after having fallen prey". In regards to malaria, Ramazzini was one of the first to support the use of the quinine-rich bark cinchona.