Crop diversity fruit trees and banana plants) are cloned. A single pest or disease could threaten a whole crop due to this uniformity ("genetic erosion"). A well-known historic case was the Irish Potato Famine of 1845-1847, where a vital crop with low diversity was destroyed by a single fungus. Another example is when a disease caused by a fungus affected the monocultured 1970 US corn crop, causing a loss of over one billion dollars in production. A danger to agriculture is wheat rust, a pathogenic fungus causing reddish patches, coloured by its spores. A virulent form of the wheat disease, stem rust,
Rare Disease Day leading up to Rare Disease Day included other policy-related events in numerous locations, such as a reception in the British Parliament where policymakers met with individuals with rare diseases to discuss issues such as "equal access and availability of prevention, diagnosis, treatment and rehabilitation." Rare Disease Day was observed for the first time in Panama, Colombia, Argentina, Australia, the People's Republic of China, and the United States. In the United States, NORD signed on to coordinate Rare Disease Day on February 28 and collaborated with media partner The Discovery Channel and program partner "Mystery Diagnosis", as well about 180 other