Localized disease diseases. Some diseases are capable of changing from local to disseminated diseases. Pneumonia, for example, is generally confined to one or both lungs but can become disseminated through sepsis, in which the microbe responsible for the pneumonia "seeds" the bloodstream or lymphatic system and is transported to distant sites in the body. When that occurs, the process is no longer described as a localized disease, but rather as a disseminated disease. Localized disease A localized disease is an infectious or neoplastic process that originates in and is confined to one organ system or general area in the body, such as
Cytomegalic inclusion body disease eye appearance. Further tests like ELISA can be used to detect the antigen. The cells of the infected organ show intranuclear inclusion giving the nucleus classical owls eye appearance. Further tests like ELISA can be used to detect the antigen.Virus can be grown in cell culture also. Cytomegalic inclusion body disease Cytomegalic inclusion body disease (CIBD) is a series of signs and symptoms caused by cytomegalovirus infection, toxoplasmosis or other rare infections such as herpes or rubella viruses. It can produce massive calcification of the central nervous system, and often the kidneys. Cytomegalic inclusion body disease is the most common