Willow active extract of the bark, called salicin, was isolated to its crystalline form in 1828 by Henri Leroux, a French pharmacist, and Raffaele Piria, an Italian chemist, who then succeeded in separating out the compound in its pure state. In 1897, Felix Hoffmann created a synthetically altered version of salicin (in his case derived from the "Spiraea" plant), which caused less digestive upset than pure salicylic acid. The new drug, formally acetylsalicylic acid, was named Aspirin by Hoffmann's employer Bayer AG. This gave rise to the hugely important class of drugs known as nonsteroidal anti-inflammatory drugs (NSAIDs). Some of humans'
Asa C. Matthews as collector of the United States Internal Revenue. In 1889, President Benjamin Harrison appointed Matthews comptroller of the United States Treasury. In 1893, Matthews wrote a vignette for the World's Fair predicting what life in the U.S. would be like 100 years in the future. His predictions were grandiose, predicting the U.S. having 60 states and controlling all of North America. Matthews died suddenly at his home in Pittsfield, Illinois. Asa C. Matthews Asa Carrington Matthews (March 22, 1833 – June 14, 1908) was an American lawyer, judge, and politician. Born in Pike County, Illinois, Matthews went to the public