Crop diversity are all susceptible to a single fungus, "Fusarium oxysporum" (Panama disease); large areas of the crop were destroyed by the fungus in the 1950s. 'Gros Michel' has been replaced by the current main banana on the market, the 'Cavendish', which in turn is (2015) at risk of total loss to a strain of the same fungus, 'Tropical Race 4'. Such threats can be countered by strategies such as planting multi-line cultivars and cultivar mixes, in the hope that some of the cultivars will be resistant to any individual outbreak of disease. The implications of crop diversity are at both local
History of Panama (to 1821) History of Panama (to 1821) In the history of Panama, the earliest known inhabitants were the Cueva and Coclé tribes, but they were drastically reduced by disease and fighting when the Spanish arrived in the 16th century. But some moved out of Panama to have children and increase population. Rodrigo de Bastidas, sailing westward from Venezuela in 1501 in search of gold, was the first European to explore the Isthmus of Panama. 10 years later, Vasco Núñez de Balboa visited the Isthmus and established a short-lived settlement in the Darién. Vasco Núñez de Balboa's torturous trek from the Atlantic to