Natural product to modern discovery of their active ingredients and eventually to the development of new drugs. A large number of currently prescribed drugs have been either directly derived from or inspired by natural products. A few representative examples are listed below. Some of the oldest natural product based drugs are analgesics. The bark of the willow tree has been known from antiquity to have pain relieving properties. This is due to presence of the natural product salicin which in turn may be hydrolyzed into salicylic acid. A synthetic derivative acetylsalicylic acid better known as aspirin is a widely used pain reliever.
Lune of Hippocrates give the only constructible squarable lunes; in particular, there are no constructible squarable convex lunes. Lune of Hippocrates In geometry, the lune of Hippocrates, named after Hippocrates of Chios, is a lune bounded by arcs of two circles, the smaller of which has as its diameter a chord spanning a right angle on the larger circle. Equivalently, it is a non-convex plane region bounded by one 180-degree circular arc and one 90-degree circular arc. It is the first curved figure to have its exact area calculated mathematically. Hippocrates wanted to solve the classic problem of squaring the circle, i.e. constructing