Willow active extract of the bark, called salicin, was isolated to its crystalline form in 1828 by Henri Leroux, a French pharmacist, and Raffaele Piria, an Italian chemist, who then succeeded in separating out the compound in its pure state. In 1897, Felix Hoffmann created a synthetically altered version of salicin (in his case derived from the "Spiraea" plant), which caused less digestive upset than pure salicylic acid. The new drug, formally acetylsalicylic acid, was named Aspirin by Hoffmann's employer Bayer AG. This gave rise to the hugely important class of drugs known as nonsteroidal anti-inflammatory drugs (NSAIDs). Some of humans'
Asa Townsend east of Arkona, apparently next door to an Ezekiel Townsend who was possibly his son. The Townsends had been joined in 1833 by settler Henry Utter who settled what would become the south-eastern corner of Arkona. Asa Townsend Asa Townsend (c.1775-alive 1851) was an early settler in Westminster Township near what became the City of London, Ontario. His lands ultimately became incorporated in London's Springbank Park. By the 1820s he removed westward to settle on the bank of the Ausable River in what later became Bosanquet Township in Lambton County. Here he operated a salt well. He and his wife—whose