Natural product to modern discovery of their active ingredients and eventually to the development of new drugs. A large number of currently prescribed drugs have been either directly derived from or inspired by natural products. A few representative examples are listed below. Some of the oldest natural product based drugs are analgesics. The bark of the willow tree has been known from antiquity to have pain relieving properties. This is due to presence of the natural product salicin which in turn may be hydrolyzed into salicylic acid. A synthetic derivative acetylsalicylic acid better known as aspirin is a widely used pain reliever.
Hippocrates of Chios Hippocrates of Chios Hippocrates of Chios (; c. 470 – c. 410 BC) was an ancient Greek mathematician, geometer, and astronomer. He was born on the isle of Chios, where he was originally a merchant. After some misadventures (he was robbed by either pirates or fraudulent customs officials) he went to Athens, possibly for litigation. There he became a leading mathematician. On Chios, Hippocrates may have been a pupil of the mathematician and astronomer Oenopides of Chios. In his mathematical work there probably was some Pythagorean influence too, perhaps via contacts between Chios and the neighbouring island of Samos, a