Endocrine gland cretinism in infants and myxoedema in adults. Hyperparathyroidism results in hypercalcaemia and its effects and in extreme bone wasting. Hypoparathyroidism leads to hypocalcaemia, evidenced by tetany seizure and respiratory paralysis. Hyposecretion of insulin results in diabetes mellitus; cardinal signs are polyuria, polydipsia, and polyphagia. Endocrine gland Endocrine glands are glands of the endocrine system that secrete their products, hormones, directly into the blood rather than through a duct. The major glands of the endocrine system include the pineal gland, pituitary gland, pancreas, ovaries, testes, thyroid gland, parathyroid gland, hypothalamus and adrenal glands. The hypothalamus and pituitary gland are neuroendocrine organs.
Pituitary gland distalis (pars glandularis) that constitutes ~80% of the gland. The pars intermedia (the intermediate lobe) lies between the pars distalis and the pars tuberalis, and is rudimentary in the human, although in other species it is more developed. It develops from a depression in the dorsal wall of the pharynx (stomal part) known as Rathke's pouch. The anterior pituitary contains several different types of cells that synthesize and secrete hormones. Usually there is one type of cell for each major hormone formed in anterior pituitary. With special stains attached to high-affinity antibodies that bind with distinctive hormone, at least 5