Panama disease leaves and progresses to younger leaves until the entire plant dies. Gros Michel was the only type of banana eaten in the United States from the late 19th century until after World War II. From the beginning, however, a serious disease was present in the banana plantations of Central America. The problem was first diagnosed in Panama after which it was named. Over several decades, the fungus spread from Panama to neighboring countries, moving north through Costa Rica to Guatemala and south into Colombia and Ecuador. The banana industry was in a serious crisis, so a new banana thought to
Plant disease resistance include the Ring and U-box single subunit, HECT, and CRLs. Plant signaling pathways including immune responses are controlled by several feedback pathways, which often include negative feedback; and they can be regulated by De-ubiquitination enzymes, degradation of transcription factors and the degradation of negative regulators of transcription. Plant breeders emphasize selection and development of disease-resistant plant lines. Plant diseases can also be partially controlled by use of pesticides and by cultivation practices such as crop rotation, tillage, planting density, disease-free seeds and cleaning of equipment, but plant varieties with inherent (genetically determined) disease resistance are generally preferred. Breeding for disease