Salicylic acid the product with sulfuric acid gives salicylic acid: It can also be prepared by the hydrolysis of aspirin (acetylsalicylic acid) or methyl salicylate (oil of wintergreen) with a strong acid or base. Hippocrates, Galen, Pliny the Elder and others knew that willow bark could ease pain and reduce fevers. It was used in Europe and China to treat these conditions. This remedy is mentioned in texts from ancient Egypt, Sumer and Assyria. The Cherokee and other Native Americans used an infusion of the bark for fever and other medicinal purposes. In 2014, archaeologists identified traces of salicylic acid on 7th
Hippocrates of Athens Hippocrates of Athens Hippocrates of Athens (, "Hippokrátēs"; c. 459 – 424 BC), the son of Ariphron, was a strategos of the Athenians in 424 BC, serving alongside Demosthenes. Hippocrates and Demosthenes set out from Athens to seize the long walls of Megara (which connected the city with its port Nisaea). They were unable to gain entrance into the city but they were successful after a short siege. When the Spartan general Brasidas arrived, they were compelled to withdraw, but then invaded Boeotia in a three-pronged attack. Hippocrates was given command of the land force that was to take Delium