Acetyl group known as paracetamol), and acetylsalicylic acid (better known as aspirin). The introduction of an acetyl group into a molecule is called acetylation. In biological organisms, acetyl groups are commonly transferred from acetyl-CoA to other organic molecules. Acetyl-CoA is an intermediate both in the biological synthesis and in the breakdown of many organic molecules. Acetyl-CoA is also created during the second stage of cellular respiration, the Krebs Cycle, by the action of pyruvate dehydrogenase on pyruvic acid. Histones and other proteins are often modified by acetylation. For example, on the DNA level, histone acetylation by acetyltransferases (HATs) causes an expansion of
Hippocrates of Chios Hippocrates of Chios Hippocrates of Chios (; c. 470 – c. 410 BC) was an ancient Greek mathematician, geometer, and astronomer. He was born on the isle of Chios, where he was originally a merchant. After some misadventures (he was robbed by either pirates or fraudulent customs officials) he went to Athens, possibly for litigation. There he became a leading mathematician. On Chios, Hippocrates may have been a pupil of the mathematician and astronomer Oenopides of Chios. In his mathematical work there probably was some Pythagorean influence too, perhaps via contacts between Chios and the neighbouring island of Samos, a