Ghrelin growth hormone secretagogue receptor, with the "GHS-R1b" splice being inactive) is involved in mediating a wide variety of biological effects of ghrelin, including: stimulation of growth hormone release, increase in hunger, modulation of glucose and lipid metabolism, regulation of gastrointestinal motility and secretion, protection of neuronal and cardiovascular cells, and regulation of immune function. They are present in high density in the hypothalamus and pituitary, on the vagus nerve (on both afferent cell bodies and afferent nerve endings) and throughout the gastrointestinal tract. Ghrelin promotes intestinal cell proliferation and inhibits apoptosis during inflammatory states and oxidative stress. It also suppresses
The Hormone-iums The Hormone-iums "The Hormone-iums" is the 14th episode of the sixth season of the animated comedy series "Bob's Burgers" and the overall 102nd episode, and is written by Lizzie Molyneux and Wendy Molyneux and directed by Chris Song. It aired on Fox in the United States on April 17, 2016. In the episode, Tina gets her chance to be soloist of the Hormone-iums in a play, but realizes the role could end up ruining her social status. Meanwhile, Linda comes up with a business plan that she thinks will make the Belchers rich. Tina gets her wish for Wagstaff fame,