Reflexology Similar practices have been documented in the histories of China and Egypt. Reflexology was introduced to the United States in 1913 by William H. Fitzgerald, M.D. (1872–1942), an ear, nose, and throat specialist, and Edwin F. Bowers. Fitzgerald claimed that applying pressure had an anesthetic effect on other areas of the body. It was modified in the 1930s and 1940s by Eunice D. Ingham (1889–1974), a nurse and physiotherapist. Ingham claimed that the feet and hands were especially sensitive, and mapped the entire body into "reflexes" on the feet, renaming "zone therapy" reflexology. "Modern reflexologists use Ingham's methods, or similar
Patient-reported outcome therapy is a challenge and is up to now characterized by tremendous heterogeneity. There are efforts to define core sets of patient-relevant outcome variables to be measured in clinical trials in general and for multi-modal pain therapy. Meanwhile, a core outcome measure set based on PROMS was developed with routine data and validated for operationalizing success in multimodal pain therapy. Validation studies suggest also suitability for depicting long-term success in the sense of sustainability of treatment effects. Patient-reported outcome A patient-reported outcome (PRO) is a health outcome directly reported by the patient who experienced it. It stands in contrast to