Louisville, Kentucky river traffic between the upper Ohio River and the Gulf of Mexico, the settlement first grew as a portage site. It was the founding city of the Louisville and Nashville Railroad, which grew into a system across 13 states. Today, the city is known as the home of legendary boxer Muhammad Ali, the Kentucky Derby, Kentucky Fried Chicken (KFC), the University of Louisville and its Louisville Cardinals athletic teams, Louisville Slugger baseball bats, and three of Kentucky's six "Fortune" 500 companies. Its main airport is also the site of United Parcel Service's worldwide air hub. Since 2003, Louisville's borders have
Louisville, Kentucky experienced significant residential, tourist and retail growth, including the addition of major sports complexes KFC Yum! Center and Louisville Slugger Field, conversion of waterfront industrial sites into Waterfront Park, openings of varied museums (see Museums, galleries and interpretive centers below), and the refurbishing of the former Galleria into the bustling entertainment complex Fourth Street Live!, which opened in 2004. Louisville and Jefferson County have a combined area of , of which is land and (4.33%) is covered by water. Louisville is southeasterly situated along the border between Kentucky and Indiana, the Ohio River, in north-central Kentucky at the Falls of