Copper aspirinate Copper aspirinate Copper(II) aspirinate is an aspirin chelate of copper(II) cations (Cu). It is used to treat rheumatoid arthritis. Copper aspirinate can be prepared by several methods. In one route of preparation, an excess of acetylsalicylic acid is dissolved in aqueous sodium carbonate. Sodium hydroxide is not suitable for this purpose, because it will hydrolyse acetylsalicylic acid ("ASA") into salicylic acid and sodium acetate. The resulting solution is then filtered to remove any undissolved acetylsalicylic acid and is mixed with a solution containing Cu cations (copper(II) sulfate is suitable), precipitating bright blue crystals of copper aspirinate immediately. The crystals can
Willow pattern set up on his own account in c.1793 in Stoke-on-Trent producing earthenwares: he is thought to have engraved versions of willow designs for Spode and for various other factories. It was probably for Spode that the English Willow pattern was created and first produced perhaps around 1790, because it incorporates particular, distinctive features of earlier Chinese willow scenes which were already known and imitated at the Spode factory. The Willow pattern is commonly presented in a circular or ovate frame. The waterside landscape represents a garden in the lower right side, in which a large two-storey pavilion stands. Approached by