Louisville, Kentucky river traffic between the upper Ohio River and the Gulf of Mexico, the settlement first grew as a portage site. It was the founding city of the Louisville and Nashville Railroad, which grew into a system across 13 states. Today, the city is known as the home of legendary boxer Muhammad Ali, the Kentucky Derby, Kentucky Fried Chicken (KFC), the University of Louisville and its Louisville Cardinals athletic teams, Louisville Slugger baseball bats, and three of Kentucky's six "Fortune" 500 companies. Its main airport is also the site of United Parcel Service's worldwide air hub. Since 2003, Louisville's borders have
Louisville, Georgia the Jefferson County Courthouse. Queensborough National Bank and Trust Company was founded in 1902 and is currently headquartered in Louisville, on U.S. Highway 1. Louisville is located slightly south of the center of Jefferson County at (33.004291, -82.404588). U.S. Route 1 passes through the east side of the city, leading northeast to Augusta and south to Swainsboro. U.S. Route 221 passes through the north side of downtown as Peachtree Street and leads southwest to Bartow. US-221 leaves Louisville to the north, running with US-1 to Wrens before continuing north toward Harlem. According to the United States Census Bureau, Louisville has