Localized disease diseases. Some diseases are capable of changing from local to disseminated diseases. Pneumonia, for example, is generally confined to one or both lungs but can become disseminated through sepsis, in which the microbe responsible for the pneumonia "seeds" the bloodstream or lymphatic system and is transported to distant sites in the body. When that occurs, the process is no longer described as a localized disease, but rather as a disseminated disease. Localized disease A localized disease is an infectious or neoplastic process that originates in and is confined to one organ system or general area in the body, such as
Whipple's disease dementia, memory loss, confusion, and decreased level of consciousness. Eye movement disturbances and myorhythmia (rapidly repetitive movements of the muscles) of the face, together referred to as "oculomasticatory myorhythmia", are highly characteristic for Whipple's disease. Weakness and poor coordination of part of the body, headaches, seizures, as well as a number of more uncommon neurological features, are present in some cases. "T. whipplei" is one of the actinomycetes, and is a distant relative of "Mycobacterium avium-intracellulare", and "Mycobacterium paratuberculosis" explaining in part why Whipple's disease is similar to the diseases caused by these bacteria. The disease is common in farmers