Felix Hoffmann in 1890 with the pharmaceutical state exam. In 1891 he graduated magna cum laude from the University of Munich. Two years later he earned his doctorate, also magna cum laude, after completing his thesis entitled "On certain derivatives of dihydroanthracene". In 1894, he joined Bayer as a research chemist. On 10 August 1897 Hoffmann synthesized acetylsalicylic acid (ASA) while working at Bayer under Arthur Eichengrün. By combining salicylic acid with acetic acid, he succeeded in creating ASA in a chemically pure and stable form. The pharmacologist responsible for verifying these results was skeptical at first, yet once several large-scale studies
Acid trance Acid trance Acid trance is a genre of trance music that emerged in the late 1980s and early 1990s focusing on using the acid sound. The trademark sound of "acid" is produced with a Roland TB-303 by playing a sequenced melody while altering the instrument's filter cutoff frequency, resonance, envelope modulation, and accent controls. This real-time tone adjustment was not part of the instrument's original intended operation. Acid trance is the best known form of trance music in Belgium. The form was first showcased at the popular Antwerp Rave 24 in Belgium, and has created four national number one singles