Ghrelin capacity for food but also dramatically lowers ghrelin levels compared to both lean controls and those that lost weight through dieting alone. However, studies are conflicting as to whether or not ghrelin levels return to nearly normal with gastric bypass patients in the long term after weight loss has stabilized. Bariatric surgeries involving vertical-sleeve gastrectomy reduce plasma ghrelin levels by about 60% in the long term. Ghrelin plasma concentration increases with age and this may contribute to the tendency for weight gain as people age. Ghrelin Ghrelin (pronounced ), the "hunger hormone", also known as lenomorelin (INN), is a peptide
Hormone replacement therapy risks that potentially outweigh any benefits may be due to the efforts of pharmaceutical companies like Wyeth. Hormone replacement therapy Hormone replacement therapy (HRT), also known as menopausal hormone therapy (MHT) or postmenopausal hormone therapy (PHT, PMHT), is a form of hormone therapy which is used to treat symptoms associated with menopause in women. These symptoms can include hot flashes, vaginal atrophy and dryness, and bone loss, among others, and are caused by diminished levels of sex hormones in the menopausal period. The main hormonal medications used in HRT for menopausal symptoms are estrogens and progestogens. A progestogen is usually