Localized disease diseases. Some diseases are capable of changing from local to disseminated diseases. Pneumonia, for example, is generally confined to one or both lungs but can become disseminated through sepsis, in which the microbe responsible for the pneumonia "seeds" the bloodstream or lymphatic system and is transported to distant sites in the body. When that occurs, the process is no longer described as a localized disease, but rather as a disseminated disease. Localized disease A localized disease is an infectious or neoplastic process that originates in and is confined to one organ system or general area in the body, such as
Blackleg (disease) Blackleg (disease) Blackleg, black quarter, quarter evil, or quarter ill () is an infectious bacterial disease most commonly caused by "Clostridium chauvoei", a Gram-positive bacterial species. It is seen in livestock all over the world, usually affecting cattle, sheep, and goats. It has been seen occasionally in farmed bison and deer. The acute nature of the disease makes successful treatment difficult, and the efficacy of the commonly used vaccine is disputed. Most losses due to blackleg occur when the cattle are between the ages of six months and two years, although it can occur when they are as young as