Growth hormone secretagogue receptor Growth hormone secretagogue receptor Growth hormone secretagogue receptor(GHS-R), also known as ghrelin receptor, is a G protein-coupled receptor that binds growth hormone secretagogues (GHSs), such as ghrelin, the "hunger hormone". The role of GHS-R is thought to be in regulating energy homeostasis and body weight. In the brain, they are most highly expressed in the hypothalamus, specifically the ventromedial nucleus and arcuate nucleus. GSH-Rs are also expressed in other areas of the brain, including the ventral tegmental area, hippocampus, and substantia nigra. Outside the central nervous system, too, GSH-Rs are also found in the liver, in skeletal muscle, and even
Adrenocorticotropic hormone (medication) Adrenocorticotropic hormone (medication) Adrenocorticotropic hormone is used as a medication and as diagnostic agent in the ACTH stimulation test. The form that is purified from pig pituitary glands is known as corticotropin (INN, BAN) is a medication and naturally occurring polypeptide tropic hormone produced and secreted by the anterior pituitary gland. The form that is made synthetically is tetracosactide (INN), also known as tetracosactrin (BAN) and cosyntropin (USAN), and the acetate ester, tetracosactide acetate (JAN), also known as tetracosactrin acetate (BAN). It consists of the first 24 (of a total of 39) amino acids of ACTH and retains full function