Alexander Monro (tertius) Charles found the sight of surgery so upsetting that he stopped trying and turned his attention to natural history. During Monro's tenure as Professor of Anatomy, Edinburgh was rocked by scandal due to the notorious "Burke and Hare murders" in which healthy individuals were intentionally killed in order to supply cadavers for dissection by anatomy lecturers and their students. One of the murderers, William Burke, was hanged on 28 January 1829, after which he was famously dissected at the Edinburgh Medical College by Monro himself. In a letter, Monro dipped his quill pen into Burke's blood and wrote, "This is
Aortic dissection with an aortic dissection have a previous history of hypertension. Illicit drug use with stimulants such as cocaine and methamphetamine is also a modifiable risk factor for AD. It can also be caused by smoking. A bicuspid aortic valve (a type of congenital heart disease involving the aortic valve) is found in 7–14% of individuals who have an aortic dissection. These individuals are prone to dissection in the ascending aorta. The risk of dissection in individuals with bicuspid aortic valve is not associated with the degree of stenosis of the valve. Connective tissue disorders such as Marfan syndrome, Ehlers-Danlos syndrome,