Felix Hoffmann in 1890 with the pharmaceutical state exam. In 1891 he graduated magna cum laude from the University of Munich. Two years later he earned his doctorate, also magna cum laude, after completing his thesis entitled "On certain derivatives of dihydroanthracene". In 1894, he joined Bayer as a research chemist. On 10 August 1897 Hoffmann synthesized acetylsalicylic acid (ASA) while working at Bayer under Arthur Eichengrün. By combining salicylic acid with acetic acid, he succeeded in creating ASA in a chemically pure and stable form. The pharmacologist responsible for verifying these results was skeptical at first, yet once several large-scale studies
Willow flute Russian Republic of Karelia. It is made the same way as the willow flute, but instead of willow bark, it is made out of birch bark. The Karelian Folk Music Ensemble, based out of Petrozavodsk in Russian Karelia, uses this instrument in their music. Willow flute The willow flute, also known as sallow flute (, or "sälgpipa", or "pajupilli"), is a Nordic folk flute, or whistle, consisting of a simple tube with a transverse fipple mouthpiece and no finger holes. The mouthpiece is typically constructed by inserting a grooved plug into one end of the tube, and cutting an edged