History of aspirin mid-eighteenth century. By the nineteenth century pharmacists were experimenting with and prescribing a variety of chemicals related to salicylic acid, the active component of willow extract. In 1853, chemist Charles Frédéric Gerhardt treated acetyl chloride with sodium salicylate to produce acetylsalicylic acid for the first time; in the second half of the nineteenth century, other academic chemists established the compound's chemical structure and devised more efficient methods of synthesis. In 1897, scientists at the drug and dye firm Bayer began investigating acetylsalicylic acid as a less-irritating replacement for standard common salicylate medicines, and identified a new way to synthesize it.
Willow Rosenberg Willow is capable of. When Willow eventually exhibits what power she has, it briefly frightens Kennedy. Willow worries about becoming sexually intimate with Kennedy, unsure of what may transpire if she loses control of herself. In season 7 episode 20, "Touched", in which practically all the main cast has sex (two by two) Willow and Kennedy take part in the first lesbian sex scene on primetime television. In "Season Eight", Kennedy and Willow are still romantically involved, but separated during Willow's self-exploration. Unlike her relationship with Tara, Willow is able to hold a separate identity while with Kennedy. When she