Aspirin to salicylic acid, the active component of willow extract. In 1853, chemist Charles Frédéric Gerhardt treated sodium salicylate with acetyl chloride to produce acetylsalicylic acid for the first time; in the second half of the nineteenth century, other academic chemists established the compound's chemical structure and devised more efficient methods of synthesis. In 1897, scientists at the drug and dye firm Bayer began investigating acetylsalicylic acid as a less-irritating replacement for standard common salicylate medicines, and identified a new way to synthesize it. By 1899, Bayer had dubbed this drug Aspirin and was selling it around the world. The word
Hippocrates (lunar crater) number of tiny craterlets, and is slightly wider at the southern edge with a ridge-like projection. The interior floor is level and almost featureless, with only a few tiny craterlets to mark the surface. This crater was named after Hippocrates, the ancient Greek physician. By convention these features are identified on lunar maps by placing the letter on the side of the crater midpoint that is closest to Hippocrates. Hippocrates (lunar crater) Hippocrates is a lunar impact crater on the far side of the Moon. It is located in the northern region of the lunar surface, to the north of