History of aspirin mid-eighteenth century. By the nineteenth century pharmacists were experimenting with and prescribing a variety of chemicals related to salicylic acid, the active component of willow extract. In 1853, chemist Charles Frédéric Gerhardt treated acetyl chloride with sodium salicylate to produce acetylsalicylic acid for the first time; in the second half of the nineteenth century, other academic chemists established the compound's chemical structure and devised more efficient methods of synthesis. In 1897, scientists at the drug and dye firm Bayer began investigating acetylsalicylic acid as a less-irritating replacement for standard common salicylate medicines, and identified a new way to synthesize it.
Asa Townsend Asa Townsend Asa Townsend (c.1775-alive 1851) was an early settler in Westminster Township near what became the City of London, Ontario. His lands ultimately became incorporated in London's Springbank Park. By the 1820s he removed westward to settle on the bank of the Ausable River in what later became Bosanquet Township in Lambton County. Here he operated a salt well. He and his wife—whose name is not known—are credited with being the first white settlers in the area of the present village of Arkona, Ontario. Asa was still living at the time of the 1851 Bosanquet Township assessment, living just