Willow active extract of the bark, called salicin, was isolated to its crystalline form in 1828 by Henri Leroux, a French pharmacist, and Raffaele Piria, an Italian chemist, who then succeeded in separating out the compound in its pure state. In 1897, Felix Hoffmann created a synthetically altered version of salicin (in his case derived from the "Spiraea" plant), which caused less digestive upset than pure salicylic acid. The new drug, formally acetylsalicylic acid, was named Aspirin by Hoffmann's employer Bayer AG. This gave rise to the hugely important class of drugs known as nonsteroidal anti-inflammatory drugs (NSAIDs). Some of humans'
ASA Late Model Series was renamed the ASA Late Model Challenge Series. As part of the splinter of the American Speed Association caused by the 2004 season, the American Speed Association was broken up. The Late Model Series was reacquired by Varney, while other assets were sold to Racing Speed Associates, led by Dennis Huth. On December, 2007, Dennis Huth filed a lawsuit against the ASA Late Model Series seeking to invalidate and cancel the ASA Late Model Series trademark registration. The ASA Late Model Series responded that the lawsuit is frivolous and without merit and plan counter sue Mr. Huth for damages caused