Peptide hormone growth hormone, which acts on bone, muscle, and the liver. The posterior pituitary gland secretes antidiuretic hormone, also called vasopressin, and oxytocin. The parathyroid gland secretes parathyroid hormone, the main hormone responsible for regulating serum calcium and phosphorus levels. Peptide hormones are also produced by many different organs and tissues, including the heart (atrial-natriuretic peptide (ANP) or atrial natriuretic factor (ANF)) and pancreas (glucagon, insulin and somatostatin), the gastrointestinal tract (cholecystokinin, gastrin), and adipose tissue stores (leptin). Peptide hormone Peptide hormones or protein hormones are hormones whose molecules are peptides or proteins, respectively. The latter have longer amino acid chain
Pineal gland increase in the concentration of FSH and LH within the gland. Administration of melatonin did not return the concentrations of FSH to normal levels, suggesting that the pineal gland influences pituitary gland secretion of FSH and LH through an undescribed transmitting molecule. The pineal gland contains receptors for the regulatory neuropeptide, endothelin-1, which, when injected in picomolar quantities into the lateral cerebral ventricle, causes a calcium-mediated increase in pineal glucose metabolism. Studies on rodents suggest that the pineal gland may influence the actions of recreational drugs, such as cocaine, and antidepressants, such as fluoxetine (Prozac), and that its hormone melatonin