Salicylic acid the OH group is "ortho" to the carboxyl group. It is also known as 2-hydroxybenzoic acid. It is poorly soluble in water (2 g/L at 20 °C). Aspirin (acetylsalicylic acid or ASA) can be prepared by the esterification of the phenolic hydroxyl group of salicylic acid with the acetyl group from acetic anhydride or acetyl chloride. Salicylic acid can also be prepared using the Kolbe-Schmitt reaction. Salicylic acid is used as a food preservative, a bactericidal and an antiseptic. Sodium salicylate is a useful phosphor in the vacuum ultraviolet spectral range, with nearly flat quantum efficiency for wavelengths between 10
Hippocrates of Athens Hippocrates of Athens Hippocrates of Athens (, "Hippokrátēs"; c. 459 – 424 BC), the son of Ariphron, was a strategos of the Athenians in 424 BC, serving alongside Demosthenes. Hippocrates and Demosthenes set out from Athens to seize the long walls of Megara (which connected the city with its port Nisaea). They were unable to gain entrance into the city but they were successful after a short siege. When the Spartan general Brasidas arrived, they were compelled to withdraw, but then invaded Boeotia in a three-pronged attack. Hippocrates was given command of the land force that was to take Delium