Amazon rubber boom the expansion of Iquitos in Peru. The rubber boom occurred largely between 1879 and 1912. There was heightened rubber production and associated activities from 1942 to 1945 during the Second World War. Natural rubber is an elastomer, also known as tree gum, India rubber, and "caoutchouc," which comes from the rubber tree in tropical regions. Christopher Columbus was the one of the first Europeans to bring news of this odd substance back to Europe, but he was not the only one to report it. Around 1736, a French astronomer recalled how Amerindians used rubber to waterproof shoes and cloaks. He
Natural product the isolation of "analytical quantities" of the substance of interest, where the focus is on identification and quantitation of the substance (e.g. in biological tissue or fluid), and where the quantity isolated depends on the analytical method applied (but is generally always sub-microgram in scale). The ease with which the active agent can be isolated and purified depends on the structure, stability, and quantity of the natural product. The methods of isolation applied toward achieving these two distinct scales of product are likewise distinct, but generally involve extraction, precipitation, adsorptions, chromatography, and sometimes crystallizations. In both cases, the isolated substance