Multiple electrode aggregometry and ADP-receptors. Adding ASA (acetylsalicylic acid) reagent to a blood sample reduces the aggregation responses in ASPItest and COLtest. ASA irreversibly inhibits COX1 in platelets, thereby inhibiting the production of TXA2. The ASA Reagent is used as a quality control in the platelet function testing with Multiplate, allowing the assessment of abnormal platelet responses in ASPItest and COLtest. This reagent is used as a quality control in Multiplate platelet function testing. The GPIIb/IIIa antagonist blocks the binding of fibrinogen to the GPIIb/IIIa receptors, preventing the formation of platelet-fibrinogen bonds and resulting in significantly reduced platelet aggregation in response to all
Willow Bunch, Saskatchewan Willow Bunch community, settled in what is part of the present-day Jean Louis Légaré Regional Park. Légaré, who married into the Métis community, opened a trading post/store there, and often traded various necessities to the local Métis for bison goods. In the spring of 1881, it was estimated he had around $3,000 worth of bison products in his store. A boy named Édouard Beaupré, better known as the Willow Bunch Giant, was the first child born and baptized in the area in 1881. The forerunner settlement of Willow Bunch was established in 1883, around two miles east of Légaré's store