Natural product to modern discovery of their active ingredients and eventually to the development of new drugs. A large number of currently prescribed drugs have been either directly derived from or inspired by natural products. A few representative examples are listed below. Some of the oldest natural product based drugs are analgesics. The bark of the willow tree has been known from antiquity to have pain relieving properties. This is due to presence of the natural product salicin which in turn may be hydrolyzed into salicylic acid. A synthetic derivative acetylsalicylic acid better known as aspirin is a widely used pain reliever.
Bark hack The first sentence is basically correct except that the blade is straight rather than curved. With the bark hack, only the bark is removed; it does not cut into the wood as the wood hack did. The wood hack was used up until the early 1950's and the trees were "chipped or streaked" each week during the sap flow season. With the bark hack, only the bark was removed and a 50% sulfuric acid solution was sprayed on the "streak" and it had to be done only every 2 weeks. Bark hack A bark hack is a tool used to