Crop diversity fruit trees and banana plants) are cloned. A single pest or disease could threaten a whole crop due to this uniformity ("genetic erosion"). A well-known historic case was the Irish Potato Famine of 1845-1847, where a vital crop with low diversity was destroyed by a single fungus. Another example is when a disease caused by a fungus affected the monocultured 1970 US corn crop, causing a loss of over one billion dollars in production. A danger to agriculture is wheat rust, a pathogenic fungus causing reddish patches, coloured by its spores. A virulent form of the wheat disease, stem rust,
Plant disease resistance for disease resistance originated with Sir Rowland Biffen, who identified a single recessive gene for resistance to wheat yellow rust. Nearly every crop was then bred to include disease resistance (R) genes, many by introgression from compatible wild relatives. The term GM ("genetically modified") is often used as a synonym of transgenic to refer to plants modified using recombinant DNA technologies. Plants with transgenic/GM disease resistance against insect pests have been extremely successful as commercial products, especially in maize and cotton, and are planted annually on over 20 million hectares in over 20 countries worldwide (see also genetically modified crops).