Insulin (medication) testing and occasionally skin biopsy. First line therapy against insulin hypersensitivity reactions include symptomatic therapy with antihistamines. The affected persons are then switched to a preparation that does not contain the specific agent they are reacting to or undergo desensitization. Insulin is an endogenous hormone, which is produced by the pancreas. The insulin protein has been highly conserved across evolutionary time, and is present in both mammals and invertebrates. The insulin/insulin-like growth factor signalling pathway (IIS) has been extensively studied in species including nematode worms (e.g."C. elegans"), flies ("Drosophila melanogaster") and mice ("Mus musculus"). Its mechanisms of action are highly
Gland (botany) Gland (botany) In plants, a gland is defined functionally as a plant structure which secretes one or more products. This may be located on or near the plant surface and secrete externally, or be internal to the plant and secrete into a canal or reservoir. Examples include glandular hairs, nectaries, hydathodes, and the resin canals in Pinus. The salt glands of mangroves such as "Acanthus", "Aegiceras", "Aegialitis" and "Avicennia" are a distinctive multicellular trichome, a glandular hair found on the upper leaf surface and much more densely in the abaxial indumentum. On the upper leaf surface they are sunken in