Bayer 1853—a modification of salicylic acid or salicin, a folk remedy found in the bark of the willow plant. By 1899 Bayer's trademark Aspirin was registered worldwide for Bayer's brand of acetylsalicylic acid, but it lost its trademark status in the United States, France and the United Kingdom after the confiscation of Bayer's US assets and trademarks during World War I by the United States, and because of the subsequent widespread usage of the word. The term "aspirin" continued to be used in the US, UK and France for all brands of the drug, but it is still a registered trademark
Willow pattern set up on his own account in c.1793 in Stoke-on-Trent producing earthenwares: he is thought to have engraved versions of willow designs for Spode and for various other factories. It was probably for Spode that the English Willow pattern was created and first produced perhaps around 1790, because it incorporates particular, distinctive features of earlier Chinese willow scenes which were already known and imitated at the Spode factory. The Willow pattern is commonly presented in a circular or ovate frame. The waterside landscape represents a garden in the lower right side, in which a large two-storey pavilion stands. Approached by