Byssinosis not brown. Brown lung can ultimately result in narrowing of the airways, lung scarring and death from infection or respiratory failure. Patient history should reveal exposure to cotton, flax, hemp, or jute dust. Diagnostic tests include a lung function test and a chest x ray or CT scan. Measurable change in lung function before and after working shifts is key to diagnosis. Patients suffering from byssinosis show a significant drop in FEV1 over the course of work shift. Chest radiographs show areas of opacity due to fibrosis of the pulmonary parenchyma. Affected workers should be offered alternative employment. Continued exposure
Extramammary Paget's disease in 1893, Darier and Coulillaud described the perianal location of EMPD. Extramammary Paget's disease Extramammary Paget’s Disease (EMPD), is a rare and slow-growing malignancy which occurs within the epithelium and accounts for 6.5% of all Paget’s disease. The clinical presentation of this disease is similar to the characteristics of Mammary Paget’s disease (MPD). However, unlike MPD, which occurs in large lactiferous ducts and then extends into the epidermis, EMPD originates in glandular regions rich in apocrine secretions outside the mammary glands. EMPD incidence is increasing by 3.2% every year, affecting hormonally-targeted tissues such as the vulva and scrotum. In women,