Crop diversity between 20 and 90 percent crop losses in the Congo. The FAO emergency relief and rehabilitation program is assisting vulnerable returnee populations in the African Great Lakes Region through mass propagation and distribution of CMD resistant or highly tolerant cassava. A well known occurrence of disease susceptibility in crops lacking diversity concerns the 'Gros Michel', a seedless banana that saw world marketing in the 1940s. As the market demand became high for this particular cultivar, growers and farmers began to use the Gros Michel banana almost exclusively. Genetically, these bananas are clones, and because of this lack of genetic diversity,
Plant disease resistance include the Ring and U-box single subunit, HECT, and CRLs. Plant signaling pathways including immune responses are controlled by several feedback pathways, which often include negative feedback; and they can be regulated by De-ubiquitination enzymes, degradation of transcription factors and the degradation of negative regulators of transcription. Plant breeders emphasize selection and development of disease-resistant plant lines. Plant diseases can also be partially controlled by use of pesticides and by cultivation practices such as crop rotation, tillage, planting density, disease-free seeds and cleaning of equipment, but plant varieties with inherent (genetically determined) disease resistance are generally preferred. Breeding for disease