Bayer 1853—a modification of salicylic acid or salicin, a folk remedy found in the bark of the willow plant. By 1899 Bayer's trademark Aspirin was registered worldwide for Bayer's brand of acetylsalicylic acid, but it lost its trademark status in the United States, France and the United Kingdom after the confiscation of Bayer's US assets and trademarks during World War I by the United States, and because of the subsequent widespread usage of the word. The term "aspirin" continued to be used in the US, UK and France for all brands of the drug, but it is still a registered trademark
Hippocrates the year 460 BC on the Greek island of Kos; other biographical information, however, is likely to be untrue. Soranus of Ephesus, a 2nd-century Greek physician, was Hippocrates' first biographer and is the source of most personal information about him. Later biographies are in the "Suda" of the 10th century AD, and in the works of John Tzetzes, Aristotle's "Politics", which date from the 4th century BC. Soranus wrote that Hippocrates' father was Heraclides, a physician, and his mother was Praxitela, daughter of Tizane. The two sons of Hippocrates, Thessalus and Draco, and his son-in-law, Polybus, were his students. According