Willow active extract of the bark, called salicin, was isolated to its crystalline form in 1828 by Henri Leroux, a French pharmacist, and Raffaele Piria, an Italian chemist, who then succeeded in separating out the compound in its pure state. In 1897, Felix Hoffmann created a synthetically altered version of salicin (in his case derived from the "Spiraea" plant), which caused less digestive upset than pure salicylic acid. The new drug, formally acetylsalicylic acid, was named Aspirin by Hoffmann's employer Bayer AG. This gave rise to the hugely important class of drugs known as nonsteroidal anti-inflammatory drugs (NSAIDs). Some of humans'
Hippocrates Hippocrates II is: 1. Hippocrates II. "The Father of Medicine" 2. Heraclides 4. Hippocrates I. 8. Gnosidicus 16. 32. Sostratus III. 64. Theodorus II. 128. Sostratus, II. 256. Thedorus 512. Cleomyttades 1024. Crisamis 2048. Dardanus 4096. Sostratus 8192. Hippolochus 16384. Podalirius 32768. Asklepius Some clinical symptoms and signs have been named after Hippocrates as he is believed to be the first person to describe those. Hippocratic face is the change produced in the countenance by death, or long sickness, excessive evacuations, excessive hunger, and the like. Clubbing, a deformity of the fingers and fingernails, is also known as Hippocratic fingers.