Ghrelin Ghrelin Ghrelin (pronounced ), the "hunger hormone", also known as lenomorelin (INN), is a peptide hormone produced by ghrelinergic cells in the gastrointestinal tract that functions as a neuropeptide in the central nervous system. Besides regulating appetite, ghrelin also plays a significant role in regulating the distribution and rate of use of energy. When the stomach is empty, ghrelin is secreted. When the stomach is stretched, secretion stops. It acts on hypothalamic brain cells both to increase hunger, and to increase gastric acid secretion and gastrointestinal motility to prepare the body for food intake. The receptor for ghrelin, the ghrelin/growth
Hormone replacement therapy risks that potentially outweigh any benefits may be due to the efforts of pharmaceutical companies like Wyeth. Hormone replacement therapy Hormone replacement therapy (HRT), also known as menopausal hormone therapy (MHT) or postmenopausal hormone therapy (PHT, PMHT), is a form of hormone therapy which is used to treat symptoms associated with menopause in women. These symptoms can include hot flashes, vaginal atrophy and dryness, and bone loss, among others, and are caused by diminished levels of sex hormones in the menopausal period. The main hormonal medications used in HRT for menopausal symptoms are estrogens and progestogens. A progestogen is usually