Willow bark of the willow tree have been mentioned in ancient texts from Assyria, Sumer and Egypt as a remedy for aches and fever, and in Ancient Greece the physician Hippocrates wrote about its medicinal properties in the fifth century BC. Native Americans across the Americas relied on it as a staple of their medical treatments. It provides temporary pain relief. Salicin is metabolized into salicylic acid in the human body, and is a precursor of aspirin. In 1763, its medicinal properties were observed by the Reverend Edward Stone in England. He notified the Royal Society, which published his findings. The
Acid trance Acid trance Acid trance is a genre of trance music that emerged in the late 1980s and early 1990s focusing on using the acid sound. The trademark sound of "acid" is produced with a Roland TB-303 by playing a sequenced melody while altering the instrument's filter cutoff frequency, resonance, envelope modulation, and accent controls. This real-time tone adjustment was not part of the instrument's original intended operation. Acid trance is the best known form of trance music in Belgium. The form was first showcased at the popular Antwerp Rave 24 in Belgium, and has created four national number one singles