Serum amyloid P component conserved in all vertebrates and also found in distant invertebrates such as the horseshoe crab (Limulus polyphemus). Serum amyloid P component The serum amyloid P component (SAP) is the identical serum form of amyloid P component (AP), a 25kDa pentameric protein first identified as the pentagonal constituent of in vivo pathological deposits called "amyloid". APCS is its human gene. AP makes up 14% of the dry mass of amyloid deposits and is thought to be an important contributor to the pathogenesis of a related group of diseases called the Amyloidoses. These conditions are characterised by the ordered aggregation of normal
New Blood (Blood, Sweat & Tears album) Bargeron on trombone and Lou Marini on sax." Album - Billboard (United States) New Blood (Blood, Sweat & Tears album) New Blood is the fifth album by the band Blood, Sweat & Tears, released in 1972. With David Clayton-Thomas leaving as lead vocalist to pursue a solo career after the release of "BS&T 4", a nearly wholesale personnel change occurred for "New Blood". Difficulties had arisen inside the group between its pop-rock and jazz factions, with Clayton-Thomas choosing to leave in early January 1972, along with founding member Fred Lipsius. Clayton-Thomas was briefly replaced by Bobby Doyle, and a photo