Serum amyloid P component conserved in all vertebrates and also found in distant invertebrates such as the horseshoe crab (Limulus polyphemus). Serum amyloid P component The serum amyloid P component (SAP) is the identical serum form of amyloid P component (AP), a 25kDa pentameric protein first identified as the pentagonal constituent of in vivo pathological deposits called "amyloid". APCS is its human gene. AP makes up 14% of the dry mass of amyloid deposits and is thought to be an important contributor to the pathogenesis of a related group of diseases called the Amyloidoses. These conditions are characterised by the ordered aggregation of normal
Clotting time Clotting time Clotting time is the time required for a sample of blood to coagulate in vitro under standard conditions. There are various methods for determining the clotting time, the most common being the capillary tube method. It is affected by calcium ion levels and many diseases. Normal value of clotting time is 8 to 15 minutes. For the measurement of clotting time by test tube method, blood is placed in a glass test tube and kept at 37° C. The required time is measured for the blood to clot. There are several other methods, including testing for those on