Lipid-binding serum glycoprotein Lipid-binding serum glycoprotein In molecular biology, the lipid-binding serum glycoproteins family, also known as the BPI/LBP/Plunc family or LBP/BPI/CETP family represents a family which includes mammalian lipid-binding serum glycoproteins. Members of this family include: These proteins consist of N- and C-terminal domains, which share a similar two-layer alpha/beta structure, but show little sequence identity to each other. Bactericidal permeability-increasing protein (BPI) is a potent antimicrobial protein of 456 amino acids that binds to and neutralises lipopolysaccharides from the outer membrane of Gram-negative bacteria. BPI contains two domains that adopt the same structural fold, even though they have little sequence similarity.
Blood, Sweat & Tears (Blood, Sweat & Tears album) Blood, Sweat & Tears (Blood, Sweat & Tears album) Blood, Sweat & Tears is the second album by the band Blood, Sweat & Tears, released in 1968. It was commercially successful, rising to the top of the U.S. charts for a collective seven weeks and yielding three successive Top 5 singles. It received a Grammy Award for Album of the Year in 1970 and has been certified quadruple platinum by the RIAA with sales of more than four million units in the U.S. In Canada, it enjoyed four runs and altogether eight weeks at No. 1 on the "RPM" national