Serum amyloid P component Serum amyloid P component The serum amyloid P component (SAP) is the identical serum form of amyloid P component (AP), a 25kDa pentameric protein first identified as the pentagonal constituent of in vivo pathological deposits called "amyloid". APCS is its human gene. AP makes up 14% of the dry mass of amyloid deposits and is thought to be an important contributor to the pathogenesis of a related group of diseases called the Amyloidoses. These conditions are characterised by the ordered aggregation of normal globular proteins and peptides into insoluble fibres which disrupt tissue architecture and are associated with cell death.
Blood, Sweat and Tears (album) personnel Album - Billboard (North America) Singles - Billboard (North America) Blood, Sweat and Tears (album) Blood, Sweat and Tears is the fifteenth album by singer Johnny Cash, released in 1963 (see 1963 in music). It is a collection of songs about the American working man. This includes "The Legend of John Henry's Hammer" and "Busted", the latter of which would become a single. Both would also be performed by Cash during his famous 1968 concerts at Folsom Prison and be included in the 1999 extended reissue of the album, "At Folsom Prison". The album was included on the Bear