Loire Valley (wine) by the Bretons of the area's wine stocks. By the 11th century the wines of Sancerre had a reputation across Europe for their high quality. In the High Middle Ages, the wines of the Loire Valley were the most esteemed wines in England and France, even more prized than those from Bordeaux. The Loire river has a significant effect on the mesoclimate of the region, adding the necessary extra few degrees of temperature that allows grapes to grow when the areas to the north and south of the Loire Valley have shown to be unfavorable to viticulture. In addition to
Loire lower Loire found its source upstream of Orléans in the region of Gien, flowing westward along the present course. At a certain point during the long history of uplift in the Paris Basin, the lower, Atlantic Loire captured the "palaeo-Loire" or "Loire séquanaise" ("Seine Loire"), producing the present river. The former bed of the "Loire séquanaise" is occupied by the Loing. The Loire Valley has been inhabited since the Middle Palaeolithic period from 40–90 ka. Neanderthal man used stone tools to fashion boats out of tree trunks and navigated the river. Modern man inhabited the Loire valley around 30 ka.