Serum (blood) toxic response. Blood is centrifuged to remove cellular components. Anti-coagulated blood yields plasma containing fibrinogen and clotting factors. Coagulated blood (clotted blood) yields serum without fibrinogen, although some clotting factors remain. Serum is an essential factor for the self-renewal of embryonic stem cells in combination with the cytokine leukemia inhibitory factor. The serum of convalescent patients successfully recovering (or already recovered) from an infectious disease can be used as a biopharmaceutical in the treatment of other people with that disease, because the antibodies generated by the successful recovery are potent fighters of the pathogen. Such "convalescent serum" (antiserum) is a
Blood, Sweat & Heels March 23, 2014, with a 90-minute reunion show. Brie Bythewood was dismissed from the series after the first season, and was replaced by two newcomers, Chantelle Fraser and Arzo Anwar. In April 2014, Bravo renewed "Blood, Sweat and Heels" for a second season, which premiered on March 29, 2015. On April 8, 2016, series star Daisy Lewellyn died after battling bile duct cancer. She was 36. She learned of the disease in 2015, after makeup artists noticed an unusual coloring in her eye. In the season two finale, she celebrated completing her radiation treatments. Blood, Sweat & Heels Blood, Sweat