Pennsylvania Route 343 highway remained intact for another seven years, and in 1970, PA 343 was realigned for the final time, this time onto its current alignment. The northern terminus is now at a partial interchange with I-78. Pennsylvania Route 343 Pennsylvania Route 343 (PA 343) is an route between Lebanon and Fredericksburg in Lebanon County, Pennsylvania. It begins at PA 72 and ends at Exit 6 of Interstate 78 (I-78). PA 343 heads mostly through urbanized areas near Lebanon before continuing into rural areas further north. There is a concurrency with U.S. Route 22 (US 22) near the northern terminus. PA 343
Maryland Route 343 Street to Race Street, where it ended at MD 16. Finally, MD 343 was extended to its present terminus when MD 16 bypassed Cambridge in the late 1960s. MD 343 begins where state maintenance commences on Hudson Road a short distance west of Cook Point Road near the hamlet of Hudson. The state highway heads east through a mix of farmland and forest, collecting roads that serve the peninsulas split by creeks that flow into the Choptank River to the north and the Little Choptank River to the south. MD 343 also passes through the hamlets of Cornersville and Lloyds.