Dental amalgam controversy demonstrated that mercury released from amalgam restorations does not give rise to toxic effects on the nervous system of children. More recently, a Cochrane Systematic review in 2014 found, "insufficient evidence to support or refute any adverse effects associated with amalgam or composite restorations." Those opposed to dental amalgam suggest that mercury from dental amalgam may lead to nephrotoxicity, neurobehavioural changes, autoimmunity, oxidative stress, autism, skin and mucosa alterations, non-specific symptoms and complaints, Alzheimer's disease, and multiple sclerosis. Both those opposed and those not opposed to dental amalgam recognize that amalgam has been found to be a rare contributor to
Amalgam (dentistry) problem. This phase has been shown to be the weakest phase in the set amalgam and is subject to corrosion, particularly at the tooth-amalgam interface. In 1962 a new amalgam alloy, called Dispersalloy, was introduced with the addition of a spherical silver-copper eutectic particle to the traditional lathe-cut AgSn particle in a ratio of 1:2. The mixture of these two types of particles is known as admix alloy. The benefits of this alloy was to strengthen the set amalgam and reduce the γ phase (SnHg). The increased copper in the silver-copper eutectic reacted preferentially with tin so that SnHg could