Coccinellidae of deadly crimes. Ladybirds have served as the US state insects of Delaware, Massachusetts, New Hampshire, New York, Ohio, and Tennessee, though only New York has selected a species native to the United States ("Coccinella novemnotata"); the other states have all adopted an invasive European species ("Coccinella septempunctata"). They have also been adopted as the mascot of Candanchú, a ski resort near Canfranc in the Spanish Pyrenees. Coccinellidae Coccinellidae () is a widespread family of small beetles ranging in size from 0.8 to 18 mm (0.03 to 0.71 inches). The family is commonly known as ladybugs in North America, and
Linker histone H1 variants core domain, while the N- and C-termini are more divergent. At the same time H1 orthologs among mammals are highly conserved across the whole protein sequence, for example human and mouse H1.4 share 93.6% sequence identity. The extent to which individual H1 variants can be redundant and what their distinct functions are isn’t yet clear. The fact that many individual H1 variant knockouts in mice are viable and show compensation by other H1 variants seems to support the hypothesis of redundancy. However, many lines of evidence suggest specific functions exist for H1 variants. For example, individual H1 variant knockout mice