Arthritis and osteoblasts. Osteoclast activity can be directly induced by osteoblasts through the RANK/RANKL mechanism. Lupus is a common collagen vascular disorder that can be present with severe arthritis. Other features of lupus include a skin rash, extreme photosensitivity, hair loss, kidney problems, lung fibrosis and constant joint pain. Gout is caused by deposition of uric acid crystals in the joint, causing inflammation. There is also an uncommon form of gouty arthritis caused by the formation of rhomboid crystals of calcium pyrophosphate known as pseudogout. In the early stages, the gouty arthritis usually occurs in one joint, but with time, it
Surgery for the dysfunctional sacroiliac joint with the greatest number of complications. Surgical outcome following dysfunctional sacroiliac joint correction has yet to be evaluated by multi-center studies. Multiple peer-reviewed articles have conducted followups, describing an overall success or satisfaction rate in the 70-80% range. However, one article was suggestive of poor outcomes with only 18% of patients being satisfied. Surgery has been demonstrated to also be effective for some pathologies that involve sacroiliac joint dysfunction. The one exception is inflammatory arthritis, for which surgery achieves mixed results. Surgeries for the dysfunctional sacroiliac joint are currently in their infancy, despite their many advances. Prospective and multi-center studies