Serum sickness proteins to form immune complexes. These complexes precipitate, enter the walls of blood vessels, and activate the complement cascade, initiating an inflammatory response and consuming much of the available complement component 3 (C3). The result is a leukocytoclastic vasculitis. This results in hypocomplementemia, a low C3 level in serum. They can also cause more reactions resulting in typical symptoms of serum sickness. Serum sickness can be developed as a result of exposure to antibodies derived from animals. These sera or antitoxins are generally administered to prevent or treat an infection or envenomation. Some of the drugs associated with serum sickness
Greatest Hits (Blood, Sweat & Tears album) Greatest Hits (Blood, Sweat & Tears album) Greatest Hits is a compilation album by the band Blood, Sweat & Tears, initially released in 1972. Although Blood, Sweat & Tears continued to record and tour for several more years, the band's lineup changed dramatically after "Blood, Sweat & Tears 4". This compilation album includes all of the group's best-known material up to that time. This was the group's last album to earn a Gold Record award. Columbia initially chose to incorporate the edited single versions of many of the songs, a decision which was poorly received by some fans. Some later