Coccinellidae prey species that various Coccinellidae may attack is much wider. A genus of small black ladybirds, "Stethorus", presents one example of predation on non-Sternorrhyncha; they specialise in mites as prey, notably "Tetranychus" spider mites. "Stethorus" species accordingly are important in certain examples of biological control. They are natural predators of a range of serious pests, such as the European corn borer, a moth that costs US agriculture industry more than $1 billion annually in crop losses and population control. Various larger species of Coccinellidae attack caterpillars and other beetle larvae. Several genera feed on various insects or their eggs; for
Histone variants common histone H3 variants are H3.3 and centromeric H3 variant (cenH3, called also CENPA in humans). Well studied species specific variants include H3.1, H3.2, TS H3.4 (mammals), H3.5 (hominids), H3.Y (primates). Except for cenH3 histone, H3 variants are highly sequence conserved differing only by a few amino acids. Histone H3.3 has been found to play an important role in maintaining genome integrity during the mammalian development. Histone H4 is one of the slowest evolving proteins with no functional variants in the majority of species. The reason for a lack of sequence variants remains unclear. Trypanosoma are known to have a