Toe other orthopedic problems. Morton's neuroma commonly results in pain and numbness between the third and fourth toes of the sufferer, due to it affecting the nerve between the third and fourth metatarsal bones. The big toe is also the most common locus of ingrown nails and the proximal phalanx joint of the hallux is the most common locus for gout attacks. Deformities of the foot include hammer toe, trigger toe, and claw toe. Hammer toe can be described as an abnormal contraction or “buckling” of a toe. This is done by a partial or complete dislocation of one of the
Juvenile idiopathic arthritis migration inhibitory factor has been associated with this condition. It is sometimes called "adolescent-onset Still's disease", to distinguish it from adult-onset Still's disease. However, some evidence shows the two conditions are closely related. Rheumatoid factor and ANA are generally negative in systemic JIA. Some doctors include two other, less common forms: enthesitis-related arthritis and psoriatic JIA. Enthesitis is an inflammation of the insertion points of the tendons. This form occurs most often in boys older than 8, large joints of lower extremities are commonly affected; characteristically, it causes back pain, and is linked to ankylosing spondylitis and inflammatory bowel disease.