Coccinellidae tropical countries. The name "coccinellids" is derived from the Latin word "coccineus" meaning "scarlet". The name "ladybird" originated in Britain where the insects became known as "Our Lady's bird" or the Lady beetle. Mary (Our Lady) was often depicted wearing a red cloak in early paintings, and the spots of the seven-spot ladybird (the most common in Europe) were said to symbolise her seven joys and seven sorrows. In the United States, the name was adapted to "ladybug". Common names in some other European languages have the same association, for example, the German name "Marienkäfer" translates to Marybeetle. Coccinellids are
Histone variants common histone H3 variants are H3.3 and centromeric H3 variant (cenH3, called also CENPA in humans). Well studied species specific variants include H3.1, H3.2, TS H3.4 (mammals), H3.5 (hominids), H3.Y (primates). Except for cenH3 histone, H3 variants are highly sequence conserved differing only by a few amino acids. Histone H3.3 has been found to play an important role in maintaining genome integrity during the mammalian development. Histone H4 is one of the slowest evolving proteins with no functional variants in the majority of species. The reason for a lack of sequence variants remains unclear. Trypanosoma are known to have a