Diabetes mellitus type 1 factors include having a family member with the condition. The underlying mechanism involves an autoimmune destruction of the insulin-producing beta cells in the pancreas. Diabetes is diagnosed by testing the level of sugar or glycated hemoglobin (HbA1C) in the blood. Type 1 diabetes can be distinguished from type 2 by testing for the presence of autoantibodies. There is no known way to prevent type 1 diabetes. Treatment with insulin is required for survival. Insulin therapy is usually given by injection just under the skin but can also be delivered by an insulin pump. A diabetic diet and exercise are important
Epigenetics of diabetes Type 2 apoptosis in cells upregulating this gene and renal complications when DAG binds to the product of the UNC13B gene. The production of fat hinders the ability for muscles and other cells in the body to respond properly to glucose and insulin, furthering the complications involved with diabetes. Increased levels of fat in the body and blood raises blood pressure, increases cholesterol, and causes arteriosclerosis; all of which are severely dangerous vascular complications for patients suffering from diabetes and can lead to death. The epigenetic marks H3K27me3, H3K4me3, and the Polycomb group of proteins such as Bmi-1, the H3K27me3 transferase Ezh2,