Fascial spaces of the head and neck Fascial spaces of the head and neck Fascial spaces (also termed fascial tissue spaces or tissue spaces) are potential spaces that exist between the fasciae and underlying organs and other tissues. In health, these spaces do not exist; they are only created by pathology, e.g. the spread of pus or cellulitis in an infection. The fascial spaces can also be opened during the dissection of a cadaver. The fascial spaces are different from the fasciae themselves, which are bands of connective tissue that surround structures, e.g. muscles. The opening of fascial spaces may be facilitated by pathogenic bacterial release of
Collagen, type VI, alpha 3 patient fibroblast cells using siRNA has successfully improved cellular deposition of type VI collagen in autosomal dominant UCMD, and may become a promising treatment for it. Though high expression levels of COL6A3 have been correlated with obesity and diabetes in mice, this relationship was not observed in humans. Other disorders involving muscle and connective tissue include weakness, joint laxity and contractures, and abnormal skin. Collagen, type VI, alpha 3 Collagen alpha-3(VI) chain is a protein that in humans is encoded by the "COL6A3" gene. This protein is an alpha chain of type VI collagen that aids in microfibril formation. As