Serum amyloid P component conserved in all vertebrates and also found in distant invertebrates such as the horseshoe crab (Limulus polyphemus). Serum amyloid P component The serum amyloid P component (SAP) is the identical serum form of amyloid P component (AP), a 25kDa pentameric protein first identified as the pentagonal constituent of in vivo pathological deposits called "amyloid". APCS is its human gene. AP makes up 14% of the dry mass of amyloid deposits and is thought to be an important contributor to the pathogenesis of a related group of diseases called the Amyloidoses. These conditions are characterised by the ordered aggregation of normal
Blood, Sweat & Tools Blood, Sweat & Tools Blood, Sweat & Tools is a Canadian television series broadcast on Discovery Channel. The series is hosted by Helder Brum, Rob Koci and Hillary Manion, who also act as the challenge judges and expert advisers to the contestants. The series is the successor of "Canada's Worst Handyman", and has a broadly similar format, but with an emphasis on rewarding competent handiwork rather than finding the nation's worst handyman. The couples are divided into teams, who are each tasked with undertaking a number of handiwork-related challenges, with the overall goal of improving their skills and confidence. At