Serum (blood) form of immunotherapy. Blood serum and plasma are some of the largest sources of biomarkers, whether for diagnostics or therapeutics. Its vast dynamic range, further complicated by the presence of lipids, salts, and post-translational modifications, as well multiple mechanisms of degradation, presents challenges in analytical reproducibility, sensitivity, resolution, and potential efficacy. For analysis of biomarkers in blood serum samples, it is possible to do a pre-separation by free-flow electrophoresis that usually consists of a depletion of serum albumin protein. This method enables greater penetration of the proteome via separation of a wide variety of charged or chargeable analytes, ranging from
Greatest Hits (Blood, Sweat & Tears album) Greatest Hits (Blood, Sweat & Tears album) Greatest Hits is a compilation album by the band Blood, Sweat & Tears, initially released in 1972. Although Blood, Sweat & Tears continued to record and tour for several more years, the band's lineup changed dramatically after "Blood, Sweat & Tears 4". This compilation album includes all of the group's best-known material up to that time. This was the group's last album to earn a Gold Record award. Columbia initially chose to incorporate the edited single versions of many of the songs, a decision which was poorly received by some fans. Some later