Serum (blood) toxic response. Blood is centrifuged to remove cellular components. Anti-coagulated blood yields plasma containing fibrinogen and clotting factors. Coagulated blood (clotted blood) yields serum without fibrinogen, although some clotting factors remain. Serum is an essential factor for the self-renewal of embryonic stem cells in combination with the cytokine leukemia inhibitory factor. The serum of convalescent patients successfully recovering (or already recovered) from an infectious disease can be used as a biopharmaceutical in the treatment of other people with that disease, because the antibodies generated by the successful recovery are potent fighters of the pathogen. Such "convalescent serum" (antiserum) is a
Blood, Sweat and Stanley Poole Blood, Sweat and Stanley Poole Blood, Sweat and Stanley Poole is a 1961 play by William Goldman and James Goldman. Both Goldman brothers had served in the army and the play is about a supply sergeant at an army post in the south. William Goldman later recalled "we had both been in the army at the same time and it seemed like a decent enough idea and magically we got it on." William and James Goldman had been permitted to serve together in the army in 1955. They were stationed with the 101th Airborne division. The Goldman brothers had received