Coccinellidae tropical countries. The name "coccinellids" is derived from the Latin word "coccineus" meaning "scarlet". The name "ladybird" originated in Britain where the insects became known as "Our Lady's bird" or the Lady beetle. Mary (Our Lady) was often depicted wearing a red cloak in early paintings, and the spots of the seven-spot ladybird (the most common in Europe) were said to symbolise her seven joys and seven sorrows. In the United States, the name was adapted to "ladybug". Common names in some other European languages have the same association, for example, the German name "Marienkäfer" translates to Marybeetle. Coccinellids are
Common disease-common variant hypothesis has held true in the case of putative causal variants in apolipoprotein E, including "APOE" ε4, associated with Alzheimer's disease. IL23R has been found to be associated with Crohn's disease; the at-risk allele has a frequency 93% in the general population . One common form of variation across human genomes is called a single nucleotide polymorphism (SNP). As indicated by the name, SNPs are single base changes in the DNA. SNP variants tend to be common in different human populations. These polymorphisms have been valuable as genomic signposts, or "markers", in the search for common variants that influence susceptibility