Spanish conquest of the Aztec Empire Meanwhile, Moctezuma's ambassadors, who had been in the Spanish camp after the battles with the Tlaxcalans, continued to press Cortés to take the road to Mexico via Cholula, which was under Aztec control, rather than over , which was an ally of Tlaxcala. They were surprised Cortés had stayed in Tlaxcala so long "among a poor and ill-bred people". Cholula was one of the most important cities of Mesoamerica, the second largest, and probably the most sacred. Its huge pyramid (larger in volume than the great pyramids of Egypt) made it one of the most prestigious places of the Aztec
Aztec medicine Tezcatlipoca would induce incurable disease. Macuilxochitl (Xochipilli), would send hemorrhoids, boils, and other similar diseases. There were many other gods as well, each connected to their own set of sicknesses. The Aztec believed that different gods were associated with different diseases or ailments as the Aztec in their medicine the Aztec would treat aliments and not what we think of as diseases. The god of the waters, Tlaloc, was connected with damp and cold as well as being responsible for the ailments that we know of today to be signs of alcoholism. Xipe Totec, the flayed one, punished people with