Serum amyloid P component conserved in all vertebrates and also found in distant invertebrates such as the horseshoe crab (Limulus polyphemus). Serum amyloid P component The serum amyloid P component (SAP) is the identical serum form of amyloid P component (AP), a 25kDa pentameric protein first identified as the pentagonal constituent of in vivo pathological deposits called "amyloid". APCS is its human gene. AP makes up 14% of the dry mass of amyloid deposits and is thought to be an important contributor to the pathogenesis of a related group of diseases called the Amyloidoses. These conditions are characterised by the ordered aggregation of normal
Greatest Hits (Blood, Sweat & Tears album) Greatest Hits (Blood, Sweat & Tears album) Greatest Hits is a compilation album by the band Blood, Sweat & Tears, initially released in 1972. Although Blood, Sweat & Tears continued to record and tour for several more years, the band's lineup changed dramatically after "Blood, Sweat & Tears 4". This compilation album includes all of the group's best-known material up to that time. This was the group's last album to earn a Gold Record award. Columbia initially chose to incorporate the edited single versions of many of the songs, a decision which was poorly received by some fans. Some later