Dental amalgam controversy demonstrated that mercury released from amalgam restorations does not give rise to toxic effects on the nervous system of children. More recently, a Cochrane Systematic review in 2014 found, "insufficient evidence to support or refute any adverse effects associated with amalgam or composite restorations." Those opposed to dental amalgam suggest that mercury from dental amalgam may lead to nephrotoxicity, neurobehavioural changes, autoimmunity, oxidative stress, autism, skin and mucosa alterations, non-specific symptoms and complaints, Alzheimer's disease, and multiple sclerosis. Both those opposed and those not opposed to dental amalgam recognize that amalgam has been found to be a rare contributor to
Dental amalgam controversy safety and effectiveness of amalgam restorations. In 2012, the Australian Dental Association published a position paper on the safety of dental amalgam. Their position is that "Dental Amalgam has been used as a dental restorative material for more than 150 years. It has proved to be a durable, safe and effective material which has been the subject of extensive research over this time" and that "amalgam should continue to be available as a dental restorative material". Scientific Committee on Emerging and Newly Identified Health Risks (SCENIHR) is a scientific committee within the European Commission. In a 2008 document of 74