Gout Less antigenic versions are in development. Gout Gout is a form of inflammatory arthritis characterized by recurrent attacks of a red, tender, hot, and swollen joint. Pain typically comes on rapidly, reaching maximal intensity in less than twelve hours. The joint at the base of the big toe is affected in about half of cases. It may also result in tophi, kidney stones, or urate nephropathy. Gout is due to persistently elevated levels of uric acid in the blood. This occurs due to a combination of diet and genetic factors. At high levels, uric acid crystallizes and the crystals deposit
The Big Toe Radio Show the Big Toe team for the day, the children could see the 'behind-the-scenes' aspects of making a radio programme. If they wished to, they could also take part in the on-air features, often having the opportunity of interviewing visiting guests such as musicians, authors, scientists, and sports stars. Its counterpart was the hour-long Little Toe Radio Show for children beginning school of age four to seven, which was broadcast daily at 7am and 3pm. In 2003, the Big Toe Reporters' Club was formed where children reported on current affairs pertaining to them – often very different from topics found on