Soft-point bullet have become available for safe use in tubular magazine rifles. Soft-point bullet A soft-point bullet (SP), also known as a soft-nosed bullet, is a jacketed expanding bullet with a soft metal core enclosed by a stronger metal jacket left open at the forward tip. A soft-point bullet is intended to expand upon striking flesh to cause a wound diameter greater than the bullet diameter. Jacketed soft point bullets are usually abbreviated "JSP" in the ammunition and reloading industry. Lead-alloy bullets used with gunpowder firearms were unsatisfactory at the bullet velocities available from rifles loaded with nitrocellulose propellants like cordite. By
C-rich stability element been mapped to a pyrimidine-rich segment of its 3' UTR. This region confers stability by directing the assembly of a specific alpha ribonucleoprotein complex at this site. Subsequently Holcik and Liebhaber identified three other highly stable eukaryotic mRNAs that assemble the alpha globin protein complex at homologous pyrimidine-rich regions within their 3'UTRs (rabbit lipoxygenase, rat tyrosine hydroxylase, and human alpha(I)-collagen). There is some debate as to the number and identity of trans-acting factors recruited to the C-rich element. However the alpha globin poly(C)-binding protein (alphaCP) is agreed to be the core constituent of what is known as the alpha complex.