Coccinellidae of deadly crimes. Ladybirds have served as the US state insects of Delaware, Massachusetts, New Hampshire, New York, Ohio, and Tennessee, though only New York has selected a species native to the United States ("Coccinella novemnotata"); the other states have all adopted an invasive European species ("Coccinella septempunctata"). They have also been adopted as the mascot of Candanchú, a ski resort near Canfranc in the Spanish Pyrenees. Coccinellidae Coccinellidae () is a widespread family of small beetles ranging in size from 0.8 to 18 mm (0.03 to 0.71 inches). The family is commonly known as ladybugs in North America, and
Common disease-common variant to common diseases. Research has linked common SNPs to diseases such as type 2 diabetes, Alzheimer's, schizophrenia and hypertension. Common disease-common variant The common disease-common variant (often abbreviated CD-CV) hypothesis predicts that common disease-causing alleles, or variants, will be found in all human populations which manifest a given disease. Common variants (not necessarily disease-causing) are known to exist in coding and regulatory sequences of genes. According to the CD-CV hypothesis, some of those variants lead to susceptibility to complex polygenic diseases. Each variant at each gene influencing a complex disease will have a small additive or multiplicative effect on the