Dental amalgam controversy an increasing number of studies with larger sample sizes are being conducted. Those who are not opposed to amalgam claim that, aside from rare and localized tissue irritation, recent evidence-based research has continued to demonstrate no ill effects from the minute amounts of mercury exposure from amalgam fillings. A 2004 systematic review conducted by the Life Sciences Research Office, whose clients include the FDA and NIH, concluded that, "the current data are insufficient to support an association between mercury release from dental amalgam and the various complaints that have been attributed to this restoration material." A systematic review in 2009
Amalgam (dentistry) problem. This phase has been shown to be the weakest phase in the set amalgam and is subject to corrosion, particularly at the tooth-amalgam interface. In 1962 a new amalgam alloy, called Dispersalloy, was introduced with the addition of a spherical silver-copper eutectic particle to the traditional lathe-cut AgSn particle in a ratio of 1:2. The mixture of these two types of particles is known as admix alloy. The benefits of this alloy was to strengthen the set amalgam and reduce the γ phase (SnHg). The increased copper in the silver-copper eutectic reacted preferentially with tin so that SnHg could