Lumbar fascia Lumbar fascia The lumbar fascia is an anatomic structure of the lumbar region. It consists of a band or sheet of connective tissue fibres, primarily collagen, that attaches, stabilizes, encloses and separates muscles not limited to the lumbar region as the name suggests, but extending upwards over the thorax to the neck and downwards over the muscles covering the sacrum. The upper thoracic portion is thin while the lumbar and sacral regions are thicker and stronger. The lumbar fascia binds the deep muscles of the back to the spine and to the transverse processes of the vertebrae. Additionally the lumbar
Ehlers–Danlos syndromes tied to specific genetic variation. Mutations in these genes can cause EDSs: Mutations in these genes usually alter the structure, production, or processing of collagen or proteins that interact with collagen. Collagen provides structure and strength to connective tissue. A defect in collagen can weaken connective tissue in the skin, bones, blood vessels, and organs, resulting in the features of the disorder. Inheritance patterns depend on the specific syndrome. Most forms of EDSs are inherited in an autosomal dominant pattern, which means only one of the two copies of the gene in question must be altered to cause a disorder.