Pennsylvania Route 343 highway remained intact for another seven years, and in 1970, PA 343 was realigned for the final time, this time onto its current alignment. The northern terminus is now at a partial interchange with I-78. Pennsylvania Route 343 Pennsylvania Route 343 (PA 343) is an route between Lebanon and Fredericksburg in Lebanon County, Pennsylvania. It begins at PA 72 and ends at Exit 6 of Interstate 78 (I-78). PA 343 heads mostly through urbanized areas near Lebanon before continuing into rural areas further north. There is a concurrency with U.S. Route 22 (US 22) near the northern terminus. PA 343
Pennsylvania Route 343 east of Pine Meadows Golf Course before it crosses the creek. The route continues through rural areas and passes through the residential community of Shirksville. PA 343 heads north through more farmland before it comes to an intersection with US 22 (William Penn Highway) south of the community of Fredericksburg. At this point, South Pine Grove Street continues to Fredericksburg and PA 343 turns northeast to become concurrent with US 22 on four-lane divided William Penn Highway. The road runs through agricultural areas with some commercial development, passing to the south of a warehouse. PA 343 splits from US 22