Arthritis and osteoblasts. Osteoclast activity can be directly induced by osteoblasts through the RANK/RANKL mechanism. Lupus is a common collagen vascular disorder that can be present with severe arthritis. Other features of lupus include a skin rash, extreme photosensitivity, hair loss, kidney problems, lung fibrosis and constant joint pain. Gout is caused by deposition of uric acid crystals in the joint, causing inflammation. There is also an uncommon form of gouty arthritis caused by the formation of rhomboid crystals of calcium pyrophosphate known as pseudogout. In the early stages, the gouty arthritis usually occurs in one joint, but with time, it
Post-traumatic arthritis Post-traumatic arthritis Post-traumatic arthritis (PTA) is a form of osteoarthritis following an injury to a joint. Post-traumatic arthritis is a form of osteoarthritis and the former can occur after the latter. However, post-traumatic arthritis can also occur after the development of chronic inflammatory arthritis. Generally, post-traumatic arthritis is classified in two groups: post-traumatic osteoarthritis and post-traumatic inflammatory arthritis. Post-traumatic osteoarthritis is the most common variation of post-traumatic arthritis. Between 20 and 50% of all osteoarthritis cases are preceded by post-traumatic arthritis. Patients having post-traumatic osteoarthritis are usually younger than osteoarthritis patients without any previous physical injuries. Less common is post-traumatic