Serum amyloid P component conserved in all vertebrates and also found in distant invertebrates such as the horseshoe crab (Limulus polyphemus). Serum amyloid P component The serum amyloid P component (SAP) is the identical serum form of amyloid P component (AP), a 25kDa pentameric protein first identified as the pentagonal constituent of in vivo pathological deposits called "amyloid". APCS is its human gene. AP makes up 14% of the dry mass of amyloid deposits and is thought to be an important contributor to the pathogenesis of a related group of diseases called the Amyloidoses. These conditions are characterised by the ordered aggregation of normal
Blood, toil, tears, and sweat are "It [poetry] is forged slowly and painfully, link by link, with blood and sweat and tears" (Lord Alfred Douglas, 1919), "Blood, sweat, and tear-wrung millions" (Lord Byron, 1823), and "...mollifie/ It with thy teares, or sweat, or blood" (John Donne, 1611). In Latin, Cicero and Livy had used the phrase "sweat and blood". "We are in the preliminary stage of one of the greatest battles in history... That we are in action at many points—in Norway and in Holland—, that we have to be prepared in the Mediterranean. That the air battle is continuous, and that many preparations have