Aquae Calidae, Bulgaria well as from Kabyle, Mesambria (now Nessebar), Odessos, Histria, Tomis, Byzantium, Abdera, Maroneia and the islands of the Aegean, the oldest from Apollonia Pontica from the 5th century BC. The first baths at the Sanctuary of the Three Nymphs originated when the Roman Empire under Lucullus conquered the region, during the Third Mithridatic War in 72 BC. Under Trajan (98-117) nearby Anchialos became the administrative centre of the region and the baths were expanded and extended with two more swimming pools. During this time the Via Pontica was built connecting Constantinople via Deultum, Anchialos, Aquae Calidae with Dorostorum and Sexaginta
Aphanizomenon flos-aquae Aphanizomenon flos-aquae Aphanizomenon flos-aquae is a brackish and freshwater species of cyanobacteria found around the world, including the Baltic Sea and the Great Lakes. "Aphanizomenon flos-aquae" can form dense surface aggregations in freshwater (known as "cyanobacterial blooms"). These blooms occur in areas of high nutrient loading, historical or current. "Aphanizomenon flos-aquae" has both toxic and nontoxic forms. Most sources worldwide are toxic, containing both hepatic and neuroendotoxins. Most cyanobacteria (including "Aphanizomenon") produce BMAA, a neurotoxin amino acid implicated in ALS/Parkinsonism. Toxicity of "A. flos-aquae" has been reported in Canada, Germany and China. "Aphanizomenon flos-aquae" is known to produce endotoxins, the