Cobalt chelatase Cobalt chelatase Cobalt chelatase () is an enzyme that catalyzes the chemical reaction The 4 substrates of this enzyme are ATP, hydrogenobyrinic acid a,c-diamide, Co, and HO, whereas its 4 products are ADP, phosphate, cob(II)yrinic acid a,c-diamide, and H. The aerobic cobalt chelatase (aerobic cobalamin biosynthesis pathway) consists of three subunits, CobT, CobN () and CobS (). Cobalamin (vitamin B12) can be complexed with metal via the ATP-dependent reactions (aerobic pathway) (e.g., in "Pseudomonas denitrificans") or via ATP-independent reactions (anaerobic pathway) (e.g., in "Salmonella typhimurium"). The corresponding cobalt chelatases are not homologous. However, aerobic cobalt chelatase subunits CobN and CobS
Cobalt (Co). The primary decay mode for isotopes with atomic mass unit values less than that of the most abundant stable isotope, Co, is electron capture and the primary mode of decay in isotopes with atomic mass greater than 59 atomic mass units is beta decay. The primary decay products below Co are element 26 (iron) isotopes; above that the decay products are element 28 (nickel) isotopes. Cobalt compounds have been used for centuries to impart a rich blue color to glass, glazes, and ceramics. Cobalt has been detected in Egyptian sculpture, Persian jewelry from the third millennium BC, in the