Masseter muscle is partly concealed, anteriorly, by the superficial portion. Posteriorly, it is covered by the parotid gland. Along with the other three muscles of mastication (temporalis, medial pterygoid, and lateral pterygoid), the masseter is innervated by the anterior division of the mandibular division (V3) of the trigeminal nerve. The innervation pathway is: gyrus precentralis > genu capsula interna > nucleus motorius nervi trigemini > nervus trigeminus > nervus mandibularis > musculus masseter. The action of the muscle during bilateral contraction of the entire muscle is to elevate the mandible, raising the lower jaw. Elevation of the mandible occurs during the closing
Masseter muscle the hypertrophy is bilateral, asymmetry of the face may still occur due to unequal enlargement of the muscles. This extraoral enlargement may be confused with parotid salivary gland disease, dental infections, and maxillofacial neoplasms. However, no other signs are present except those involved in changes in occlusion intraorally such as pain, and the enlargement corresponds with the outline of the muscle. Most patients seek medical attention because of comments about facial appearance, and this situation may be associated with further pathology of the temporomandibular joint. Finally, the muscle undergoes spasm with malignant hyperthermia as do other skeletal muscles, but this