Serum sickness proteins to form immune complexes. These complexes precipitate, enter the walls of blood vessels, and activate the complement cascade, initiating an inflammatory response and consuming much of the available complement component 3 (C3). The result is a leukocytoclastic vasculitis. This results in hypocomplementemia, a low C3 level in serum. They can also cause more reactions resulting in typical symptoms of serum sickness. Serum sickness can be developed as a result of exposure to antibodies derived from animals. These sera or antitoxins are generally administered to prevent or treat an infection or envenomation. Some of the drugs associated with serum sickness
Blood, Sweat & Tears pursue a solo career. He was briefly replaced by Bobby Doyle and then Jerry Fisher, who went on to front the next incarnation of Blood, Sweat & Tears. Fred Lipsius left as well and was briefly replaced by Joe Henderson, before Lou Marini settled into the new lineup. Another founding member, Dick Halligan, also departed, replaced by jazz pianist Larry Willis (from the Cannonball Adderley Quintet), and Swedish guitarist Georg Wadenius, from the popular Swedish outfit Made in Sweden, joined as lead guitarist around the same time. The new edition of Blood, Sweat & Tears released "New Blood" in September