Arthritis and osteoblasts. Osteoclast activity can be directly induced by osteoblasts through the RANK/RANKL mechanism. Lupus is a common collagen vascular disorder that can be present with severe arthritis. Other features of lupus include a skin rash, extreme photosensitivity, hair loss, kidney problems, lung fibrosis and constant joint pain. Gout is caused by deposition of uric acid crystals in the joint, causing inflammation. There is also an uncommon form of gouty arthritis caused by the formation of rhomboid crystals of calcium pyrophosphate known as pseudogout. In the early stages, the gouty arthritis usually occurs in one joint, but with time, it
Arthritis Care four national offices (in Scotland, Northern Ireland, Wales and England). All activities are coordinated by an office in London. Arthritis Care's CEO is Judi Rhys. Arthur Mainwaring Bowen - Founder Arthur Mainwaring Bowen founded the British Rheumatic Association (BRA) in 1947 at the age of 25. It would later be renamed Arthritis Care in 1980. Bowen’s awareness of the needs of people with arthritis began when, at the age of 19, he was diagnosed with Ankylosing Spondylitis (inflammatory arthritis, primarily affecting the spine). Meeting other young people with arthritis, during long stays in hospital, opened Bowen’s eyes to the isolation