Fascia these contain the fascial compartments of the leg and the fascial compartments of the thigh. A fasciotomy may be used to relieve compartment syndrome as a result of high pressure within a fascial compartment. Fascia A fascia (; plural fasciae ; adjective fascial; from Latin: "band") is a band or sheet of connective tissue, primarily collagen, beneath the skin that attaches, stabilizes, encloses, and separates muscles and other internal organs. Fascia is classified by layer, as "superficial fascia", deep fascia, and "visceral" or "parietal" fascia, or by its function and anatomical location. Like ligaments, aponeuroses, and tendons, fascia is made
Collagen, type XVII, alpha 1 of laminin 5 into the matrix requires collagen XVII. Mutations in the human collagen XVII gene, , lead to the absence or structural alterations and mutations of collagen XVII. The functional consequences include diminished epidermal adhesion and skin blistering in response to minimal shearing forces. The disorder caused by biallelic COL17A1 mutations and is called junctional epidermolysis bullosa, an autosomal recessive skin disease with variable clinical phenotypes. Morphological characteristics of junctional epidermolysis bullosa are rudimentary hemidesmosomes and subepidermal tissue separation. Clinical hallmarks, in addition to blisters and erosions of the skin and mucous membranes, include nail dystrophy, loss of hair,