Coccinellidae tropical countries. The name "coccinellids" is derived from the Latin word "coccineus" meaning "scarlet". The name "ladybird" originated in Britain where the insects became known as "Our Lady's bird" or the Lady beetle. Mary (Our Lady) was often depicted wearing a red cloak in early paintings, and the spots of the seven-spot ladybird (the most common in Europe) were said to symbolise her seven joys and seven sorrows. In the United States, the name was adapted to "ladybug". Common names in some other European languages have the same association, for example, the German name "Marienkäfer" translates to Marybeetle. Coccinellids are
Common disease-common variant Common disease-common variant The common disease-common variant (often abbreviated CD-CV) hypothesis predicts that common disease-causing alleles, or variants, will be found in all human populations which manifest a given disease. Common variants (not necessarily disease-causing) are known to exist in coding and regulatory sequences of genes. According to the CD-CV hypothesis, some of those variants lead to susceptibility to complex polygenic diseases. Each variant at each gene influencing a complex disease will have a small additive or multiplicative effect on the disease phenotype. These diseases, or traits, are evolutionarily neutral in part because so many genes influence the traits. The