Gout Less antigenic versions are in development. Gout Gout is a form of inflammatory arthritis characterized by recurrent attacks of a red, tender, hot, and swollen joint. Pain typically comes on rapidly, reaching maximal intensity in less than twelve hours. The joint at the base of the big toe is affected in about half of cases. It may also result in tophi, kidney stones, or urate nephropathy. Gout is due to persistently elevated levels of uric acid in the blood. This occurs due to a combination of diet and genetic factors. At high levels, uric acid crystallizes and the crystals deposit
Septic arthritis however, these can be elevated by other infections or inflammatory conditions and are, therefore, nonspecific. Procalcitonin may be more useful than CRP. Blood cultures can be positive in up to half of patients with septic arthritis. Imaging such as x-ray, CT, MRI, or ultrasound are nonspecific. They can help determine areas of inflammation but cannot confirm septic arthritis. When septic arthritis is suspected, x-rays should generally be taken. This is used to assess any problems in the surrounding structures such as bone fractures, chondrocalcinosis, and inflammatory arthritis which may predispose to septic arthritis. While x-rays may not be helpful early