Diabetes mellitus type 2 and primarily a lack of insulin secretion. Other potentially important mechanisms associated with type 2 diabetes and insulin resistance include: increased breakdown of lipids within fat cells, resistance to and lack of incretin, high glucagon levels in the blood, increased retention of salt and water by the kidneys, and inappropriate regulation of metabolism by the central nervous system. However, not all people with insulin resistance develop diabetes, since an impairment of insulin secretion by pancreatic beta cells is also required. The World Health Organization definition of diabetes (both type 1 and type 2) is for a single raised glucose reading
American Diabetes Association American Diabetes Association The American Diabetes Association (ADA) is a United States-based nonprofit that seeks to educate the public about diabetes and to help those affected by it by funding research to manage, cure and prevent diabetes (including type 1 diabetes, type 2 diabetes, gestational diabetes, and pre-diabetes). In 2016, the ADA’s total revenue was $171 million. The organization has engaged telemarketers at very large costs in the past. In one instance, the ADA entered into contract with InfoCision, a telemarketing firm that works closely with nonprofits, whereby only 15% of the expected funds raised would be given to the