Diabetes mellitus type 1 According to the current definition, two fasting glucose measurements above 126 mg/dl (7.0 mmol/l) is considered diagnostic for diabetes mellitus. In type 1, pancreatic beta cells in the islets of Langerhans are destroyed, decreasing endogenous insulin production. This distinguishes type 1's origin from type 2. Type 2 diabetes is characterized by insulin resistance, while type 1 diabetes is characterized by insulin deficiency, generally without insulin resistance. Another hallmark of type 1 diabetes is islet autoreactivity, which is generally measured by the presence of autoantibodies directed towards the beta cells. The appearance of diabetes-related autoantibodies has been shown to be able
American Diabetes Association American Diabetes Association The American Diabetes Association (ADA) is a United States-based nonprofit that seeks to educate the public about diabetes and to help those affected by it by funding research to manage, cure and prevent diabetes (including type 1 diabetes, type 2 diabetes, gestational diabetes, and pre-diabetes). In 2016, the ADA’s total revenue was $171 million. The organization has engaged telemarketers at very large costs in the past. In one instance, the ADA entered into contract with InfoCision, a telemarketing firm that works closely with nonprofits, whereby only 15% of the expected funds raised would be given to the