Dental amalgam controversy an increasing number of studies with larger sample sizes are being conducted. Those who are not opposed to amalgam claim that, aside from rare and localized tissue irritation, recent evidence-based research has continued to demonstrate no ill effects from the minute amounts of mercury exposure from amalgam fillings. A 2004 systematic review conducted by the Life Sciences Research Office, whose clients include the FDA and NIH, concluded that, "the current data are insufficient to support an association between mercury release from dental amalgam and the various complaints that have been attributed to this restoration material." A systematic review in 2009
What Is History? to suit their facts, and takes part in a dialogue between past and present. Summing up his argument, Carr puts forward his own answer to the question of "what is history?", remarking that "it is a continuous process of interaction between the historian and his facts, an unending dialogue between the past and the present." it is precisely for matters of this kind that the historian is entitled to rely on what have been called the auxiliary sciences of history In his second chapter, Carr focuses on the influence that society plays on forming the approach of the historian and