Serum amyloid P component Serum amyloid P component The serum amyloid P component (SAP) is the identical serum form of amyloid P component (AP), a 25kDa pentameric protein first identified as the pentagonal constituent of in vivo pathological deposits called "amyloid". APCS is its human gene. AP makes up 14% of the dry mass of amyloid deposits and is thought to be an important contributor to the pathogenesis of a related group of diseases called the Amyloidoses. These conditions are characterised by the ordered aggregation of normal globular proteins and peptides into insoluble fibres which disrupt tissue architecture and are associated with cell death.
Blood, Sweat & Heels Blood, Sweat & Heels Blood, Sweat & Heels is an American reality television series that premiered on January 5, 2014, on Bravo. It depicts the personal, professional, and social circle of several women who all reside in New York City. The premiere episode of "Blood, Sweat and Heels" ranked as a network best for a series premiere on Bravo at that time, averaging 2.5 million viewers and 1.4 million in the adults 18-49 viewership demo. The cast of the first season included Melyssa Ford, Demetria Lucas, Brie Bythewood, Mica Hughes, Daisy Lewellyn, and Geneva S. Thomas. The season concluded on