Lipid-binding serum glycoprotein airway smooth muscle contractility by binding to and inhibiting the Ca2+ influx channel Orai1. BPI; BPIL1; BPIL2; BPIL3; CETP; LBP; LPLUNC1; LPLUNC3; LPLUNC4; PLTP; PLUNC; SPLUNC2; Lipid-binding serum glycoprotein In molecular biology, the lipid-binding serum glycoproteins family, also known as the BPI/LBP/Plunc family or LBP/BPI/CETP family represents a family which includes mammalian lipid-binding serum glycoproteins. Members of this family include: These proteins consist of N- and C-terminal domains, which share a similar two-layer alpha/beta structure, but show little sequence identity to each other. Bactericidal permeability-increasing protein (BPI) is a potent antimicrobial protein of 456 amino acids that binds to and
Blood, toil, tears, and sweat The motion passed unanimously. This was the first of three speeches which he gave during the period of the Battle of France, which commenced on 10 May. Churchill had used similar phrases earlier, such as "Their sweat, their tears, their blood" in 1931, and "new structures of national life erected upon blood, sweat, and tears". Churchill's sentence, "I have nothing to offer but blood, toil, tears, and sweat," has been called a paraphrase of one uttered on 2 July 1849 by Giuseppe Garibaldi when rallying his revolutionary forces in Rome: "I offer hunger, thirst, forced marches, battle, and death." As