Aquae Calidae, Bulgaria well as from Kabyle, Mesambria (now Nessebar), Odessos, Histria, Tomis, Byzantium, Abdera, Maroneia and the islands of the Aegean, the oldest from Apollonia Pontica from the 5th century BC. The first baths at the Sanctuary of the Three Nymphs originated when the Roman Empire under Lucullus conquered the region, during the Third Mithridatic War in 72 BC. Under Trajan (98-117) nearby Anchialos became the administrative centre of the region and the baths were expanded and extended with two more swimming pools. During this time the Via Pontica was built connecting Constantinople via Deultum, Anchialos, Aquae Calidae with Dorostorum and Sexaginta
Aquae Iasae part of the Roman settlement was located on the highest terrace of the hill Varaždin spa, today the park and archaeological site. The residential part of "Aquae Iasae" was on the terraces that descend to the foot of the hill in the foothills of the craft-established commercial and trade show facilities. At the end of 3rd century AD Aquae Iasae were ravaged during the incursion of the Goths, then in the beginning of the 4th century the "thermae" were restored by Emperor Constantine. The resort was completely ruined and deserted in the 4th century during the invasions of the Migration