Monsanto the 1990s. Field tests were done in the United States between 1998 and 2005. As of 2017, no genetically modified wheat has been released for commercial use. Monsanto is internationally notable for its involvement in high-profile lawsuits, as both plaintiff and defendant. It defended lawsuits mostly over its products' health and environmental effects. Monsanto used the courts to enforce its patents, particularly in agricultural biotechnology, an approach similar to that of other companies in the field, such as Dupont Pioneer and Syngenta. Monsanto also became one of the most vilified large corporations in the world, over a range of issues
Monsanto was the first method for the catalytic production of pure chiral compounds. Knowles' team designed the "first industrial process to chirally synthesize an important compound"—L‑dopa, which is used to treat Parkinson's disease. In 2001, Knowles and Ryōji Noyori won the Nobel Prize in Chemistry. In the mid-1960s, chemists at Monsanto developed the Monsanto process for making acetic acid, which until 2000 was the most widely used production method. In 1964, Monsanto chemists invented AstroTurf (initially ChemGrass). In the 1960s and 1970s, Monsanto was a producer of Agent Orange for United States Armed Forces operations in Vietnam, and settled out of