Gout Gout Gout is a form of inflammatory arthritis characterized by recurrent attacks of a red, tender, hot, and swollen joint. Pain typically comes on rapidly, reaching maximal intensity in less than twelve hours. The joint at the base of the big toe is affected in about half of cases. It may also result in tophi, kidney stones, or urate nephropathy. Gout is due to persistently elevated levels of uric acid in the blood. This occurs due to a combination of diet and genetic factors. At high levels, uric acid crystallizes and the crystals deposit in joints, tendons, and surrounding tissues,
The Big Toe Radio Show conventional current affairs programmes. "The Big Toe Radio Show" ended on 16 March 2007, but the format was adapted to become the hour-long Big Toe Books on BBC Radio 7 at 4pm on weekdays and 8am on weekends. The show consisted of a presenter (Christopher Pizzey, formerly Kirsten O'Brien) introducing the story or summarising previous episodes. The last episode was broadcast on BBC Radio 4 Extra on Saturday 2 April 2011. The main presenters were: Other presenters: The Big Toe Radio Show The Big Toe Radio Show was a daily show (seven days a week) for children on the DAB