Serum sickness proteins to form immune complexes. These complexes precipitate, enter the walls of blood vessels, and activate the complement cascade, initiating an inflammatory response and consuming much of the available complement component 3 (C3). The result is a leukocytoclastic vasculitis. This results in hypocomplementemia, a low C3 level in serum. They can also cause more reactions resulting in typical symptoms of serum sickness. Serum sickness can be developed as a result of exposure to antibodies derived from animals. These sera or antitoxins are generally administered to prevent or treat an infection or envenomation. Some of the drugs associated with serum sickness
Super Hits (Blood, Sweat & Tears album) Super Hits (Blood, Sweat & Tears album) Super Hits is a budget compilation album by the band Blood, Sweat & Tears released by Columbia Records in 1998. This ten song collection draws four songs from each of the band's first two albums "Child Is Father to the Man" and "Blood, Sweat & Tears". Writing for Allmusic, critic Al Campbell wrote, "Super Hits samples ten tracks recorded by Blood, Sweat & Tears for Columbia Records in the late '60s and early '70s and includes the original versions of "Spinning Wheel," "You've Made Me So Very Happy" and "And When I Die."