Apium virus Y sea celery ("Apium prostratum"), cilantro ("Coriandrum sativum"), and bishop’s weed ("Ammi majus"). In Germany it has recently been found naturally infecting celeriac or celery root. All are members of the plant family "Apiaceae". Symptoms reported included mosaic, vein clearing or banding, necrotic/chlorotic line patterns and stunting. Some samples of parsley, celery and poison hemlock, that gave positive results in tests, however, were asymptomatic. In host range studies, the virus causes local lesions on "Chenopodium quinoa" and "C. amaraticolor" ("Amaranthaceae"). Apium virus Y "Apium virus Y" (ApVY) is a plant pathogenic virus in the genus "Potyvirus" and the virus family "Potyviridae".
Family with sequence similarity 111 member a been associated with Kenny-Caffey syndrome (KCS) type 2 and the more severe osteocraniostenosis (OCS, also known as Gracile Bone Dysplasia), both characterized by short stature, hypoparathyroidism, bone development abnormalities, and hypocalcemia. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2015]. Family with sequence similarity 111 member a Family with sequence similarity 111 member A is a protein that in humans is encoded by the FAM111A gene. The protein encoded by this gene is cell-cycle regulated, and has nuclear localization. The C-terminal half of the protein shares homology with trypsin-like peptidases and it contains a PCNA-interacting peptide (PIP)