Diabetes in dogs or Type 1, diabetes; research finds no Type 2 diabetes in dogs. Because of this, there is no possibility the permanently damaged pancreatic beta cells could re-activate to engender a remission as may be possible with some feline diabetes cases, where the primary type of diabetes is Type 2. There is another less common form of diabetes, diabetes insipidus, which is a condition of insufficient antidiuretic hormone or resistance to it. This most common form of diabetes affects approximately 0.34% of dogs. The condition is treatable and need not shorten the animal's life span or interfere with quality of life.
Genetic causes of diabetes mellitus type 2 genes, and these differences in the nucleotide sequences alter phenotypic traits that exhibit increased susceptibility to the diabetes. GWAS has revealed 65 different loci (where single nucleotide sequences differ from the patient and control group's genomes), and genes associated with type 2 diabetes, including "TCF7L2", "PPARG", "FTO", "KCNJ11","NOTCH2", "WFS1", "IGF2BP2", "SLC30A8", "JAZF1", "HHEX, DGKB, CDKN2A, CDKN2B, KCNQ1, HNF1A, HNF1B MC4R, GIPR, HNF4A, MTNR1B, PARG6, ZBED3, SLC30A8, CDKAL1, GLIS3, GCKR," among others."KCNJ11" (potassium inwardly rectifying channel, subfamily J, member 11), encodes the islet ATP-sensitive potassium channel Kir6.2, and "TCF7L2" (transcription factor 7–like 2) regulates proglucagon gene expression and thus the production