Gout Gout Gout is a form of inflammatory arthritis characterized by recurrent attacks of a red, tender, hot, and swollen joint. Pain typically comes on rapidly, reaching maximal intensity in less than twelve hours. The joint at the base of the big toe is affected in about half of cases. It may also result in tophi, kidney stones, or urate nephropathy. Gout is due to persistently elevated levels of uric acid in the blood. This occurs due to a combination of diet and genetic factors. At high levels, uric acid crystallizes and the crystals deposit in joints, tendons, and surrounding tissues,
Toe the line Toe the line "Toe the line" is an idiomatic expression meaning either to conform to a rule or standard, or to stand poised at the starting line in a footrace. Other phrases which were once used in the early 1800s and have the same meaning were toe the mark and toe the plank. The expression has disputed origins. Those suggested are from public school, the armed services, or possibly the British House of Commons. It is common practice in many long-established schools for roll-call to be taken twice a day, at which the pupils line up with their toes exactly