Serum amyloid P component conserved in all vertebrates and also found in distant invertebrates such as the horseshoe crab (Limulus polyphemus). Serum amyloid P component The serum amyloid P component (SAP) is the identical serum form of amyloid P component (AP), a 25kDa pentameric protein first identified as the pentagonal constituent of in vivo pathological deposits called "amyloid". APCS is its human gene. AP makes up 14% of the dry mass of amyloid deposits and is thought to be an important contributor to the pathogenesis of a related group of diseases called the Amyloidoses. These conditions are characterised by the ordered aggregation of normal
Blood, Sweat & Tea Blood, Sweat & Tea Blood, Sweat & Tea is a book by ambulance technician Brian Kellett, writing under the pseudonym Tom Reynolds, about life in the London Ambulance Service. The book is compiled from posts and correspondence from the blog Random Acts of Reality, one of the earliest high-readership blogs in England. The book covers Reynolds's career from 2003–2006, and discusses his career as an emergency medical technician and a rapid responder. Although often extremely critical of NHS policies and management, the book was extremely well received within the European emergency services, and the book (with its associated blog) is