Diabetes mellitus type 1 factors include having a family member with the condition. The underlying mechanism involves an autoimmune destruction of the insulin-producing beta cells in the pancreas. Diabetes is diagnosed by testing the level of sugar or glycated hemoglobin (HbA1C) in the blood. Type 1 diabetes can be distinguished from type 2 by testing for the presence of autoantibodies. There is no known way to prevent type 1 diabetes. Treatment with insulin is required for survival. Insulin therapy is usually given by injection just under the skin but can also be delivered by an insulin pump. A diabetic diet and exercise are important
Genetic causes of diabetes mellitus type 1 HLA-DQ2/DQ8) alleles. However, the HLA-DQ6 allele (HLA-DQA1*0102–DQB1*0602), if dominant, is responsible for partially preventing an organism from developing the disease. Therefore, these genetic features can be used to determine a patient's relative risk of developing the disease. Further discussion and research of the functional genomics of the pathogenesis of Type 1 Diabetes will be necessary in future studies in this field. Genetic causes of diabetes mellitus type 1 At least 20 different chromosomal regions have been linked to type 1 diabetes (T1D) susceptibility in humans, using genome screening, candidate gene testing, and studies of human homologues of mouse susceptibility genes.