Arthritis and osteoblasts. Osteoclast activity can be directly induced by osteoblasts through the RANK/RANKL mechanism. Lupus is a common collagen vascular disorder that can be present with severe arthritis. Other features of lupus include a skin rash, extreme photosensitivity, hair loss, kidney problems, lung fibrosis and constant joint pain. Gout is caused by deposition of uric acid crystals in the joint, causing inflammation. There is also an uncommon form of gouty arthritis caused by the formation of rhomboid crystals of calcium pyrophosphate known as pseudogout. In the early stages, the gouty arthritis usually occurs in one joint, but with time, it
Facet joint with large tracts of paraspinal muscles, further complicate the diagnostic approach. Typically facet joint arthritis is diagnosed with specialized physical examination by specialist physicians. Advanced imaging such as MRI or CT may be necessary to confirm the diagnosis and to rule out other conditions. Conservative treatment of facet joint arthritis involves chiropractic, physical therapy, or osteopathic medicine with correction of posture and biomechanics being the key. More advanced cases involving severe inflammatory response in the Z-joint, not unlike a swollen arthritic knee. Steroid injections may provide temporary pain relief. This is typically performed under image guidance to ensure accuracy given