Coccinellidae of deadly crimes. Ladybirds have served as the US state insects of Delaware, Massachusetts, New Hampshire, New York, Ohio, and Tennessee, though only New York has selected a species native to the United States ("Coccinella novemnotata"); the other states have all adopted an invasive European species ("Coccinella septempunctata"). They have also been adopted as the mascot of Candanchú, a ski resort near Canfranc in the Spanish Pyrenees. Coccinellidae Coccinellidae () is a widespread family of small beetles ranging in size from 0.8 to 18 mm (0.03 to 0.71 inches). The family is commonly known as ladybugs in North America, and
Common disease-common variant hypothesis has held true in the case of putative causal variants in apolipoprotein E, including "APOE" ε4, associated with Alzheimer's disease. IL23R has been found to be associated with Crohn's disease; the at-risk allele has a frequency 93% in the general population . One common form of variation across human genomes is called a single nucleotide polymorphism (SNP). As indicated by the name, SNPs are single base changes in the DNA. SNP variants tend to be common in different human populations. These polymorphisms have been valuable as genomic signposts, or "markers", in the search for common variants that influence susceptibility