Arthritis and osteoblasts. Osteoclast activity can be directly induced by osteoblasts through the RANK/RANKL mechanism. Lupus is a common collagen vascular disorder that can be present with severe arthritis. Other features of lupus include a skin rash, extreme photosensitivity, hair loss, kidney problems, lung fibrosis and constant joint pain. Gout is caused by deposition of uric acid crystals in the joint, causing inflammation. There is also an uncommon form of gouty arthritis caused by the formation of rhomboid crystals of calcium pyrophosphate known as pseudogout. In the early stages, the gouty arthritis usually occurs in one joint, but with time, it
Post-traumatic arthritis males. The process of post-traumatic arthritis can be divided into three phases: immediate, acute, and chronic. This phase usually begins a few seconds after the injury; it is characterized by cell necrosis, collagen rupture, swelling of the cartilage, hemarthrosis, and the loss of glycosaminoglycans (GAGs). In this phase, acute post-traumatic arthrosis emerges. Matrix degradation, leukocyte infiltration, inflammatory mediators, deficient lubricants, and apoptosis can occur. Typically, the acute phase comes hours after the injury. The chronic phase occurs months or years after the trauma. Typical symptoms are joint pain and dysfunction. Post-traumatic arthritis is diagnosed with the help of a patient's