Serum amyloid P component Serum amyloid P component The serum amyloid P component (SAP) is the identical serum form of amyloid P component (AP), a 25kDa pentameric protein first identified as the pentagonal constituent of in vivo pathological deposits called "amyloid". APCS is its human gene. AP makes up 14% of the dry mass of amyloid deposits and is thought to be an important contributor to the pathogenesis of a related group of diseases called the Amyloidoses. These conditions are characterised by the ordered aggregation of normal globular proteins and peptides into insoluble fibres which disrupt tissue architecture and are associated with cell death.
New Blood (Blood, Sweat & Tears album) Bargeron on trombone and Lou Marini on sax." Album - Billboard (United States) New Blood (Blood, Sweat & Tears album) New Blood is the fifth album by the band Blood, Sweat & Tears, released in 1972. With David Clayton-Thomas leaving as lead vocalist to pursue a solo career after the release of "BS&T 4", a nearly wholesale personnel change occurred for "New Blood". Difficulties had arisen inside the group between its pop-rock and jazz factions, with Clayton-Thomas choosing to leave in early January 1972, along with founding member Fred Lipsius. Clayton-Thomas was briefly replaced by Bobby Doyle, and a photo