Aquae Calidae, Bulgaria Aquae Calidae, Bulgaria Aquae Calidae (Latin for warm waters), also known as Therma and Thermopolis in the Middle Ages, was an ancient town in Thrace located in the territory of today's Bulgarian port city of Burgas. It was built around thermal baths using the hot springs and became one of the most important spa centres of ancient times. The site and baths of Aquae Calidae have been visited in the course of history by several important rulers from Philip II of Macedon to the Eastern Roman emperors Justinian I and Constantine IV, the Bulgarian ruler Terwel and the Ottoman Sultan
Aphanizomenon flos-aquae Aphanizomenon flos-aquae Aphanizomenon flos-aquae is a brackish and freshwater species of cyanobacteria found around the world, including the Baltic Sea and the Great Lakes. "Aphanizomenon flos-aquae" can form dense surface aggregations in freshwater (known as "cyanobacterial blooms"). These blooms occur in areas of high nutrient loading, historical or current. "Aphanizomenon flos-aquae" has both toxic and nontoxic forms. Most sources worldwide are toxic, containing both hepatic and neuroendotoxins. Most cyanobacteria (including "Aphanizomenon") produce BMAA, a neurotoxin amino acid implicated in ALS/Parkinsonism. Toxicity of "A. flos-aquae" has been reported in Canada, Germany and China. "Aphanizomenon flos-aquae" is known to produce endotoxins, the