Dental amalgam controversy demonstrated that mercury released from amalgam restorations does not give rise to toxic effects on the nervous system of children. More recently, a Cochrane Systematic review in 2014 found, "insufficient evidence to support or refute any adverse effects associated with amalgam or composite restorations." Those opposed to dental amalgam suggest that mercury from dental amalgam may lead to nephrotoxicity, neurobehavioural changes, autoimmunity, oxidative stress, autism, skin and mucosa alterations, non-specific symptoms and complaints, Alzheimer's disease, and multiple sclerosis. Both those opposed and those not opposed to dental amalgam recognize that amalgam has been found to be a rare contributor to
Real element formula_1, Every involution is strongly real. Furthermore, every element that is the product of two involutions is strongly real. Conversely, every strongly real element is the product of two involutions. If and formula_1 is real in formula_2 and formula_30 is odd, then formula_1 is strongly real in formula_2. The extended centralizer of an element formula_1 of a group formula_2 is defined as making the extended centralizer of an element formula_1 equal to the normalizer of the set The extended centralizer of an element of a group formula_2 is always a subgroup of formula_2. For involutions or non-real elements, centralizer and