Dental amalgam controversy demonstrated that mercury released from amalgam restorations does not give rise to toxic effects on the nervous system of children. More recently, a Cochrane Systematic review in 2014 found, "insufficient evidence to support or refute any adverse effects associated with amalgam or composite restorations." Those opposed to dental amalgam suggest that mercury from dental amalgam may lead to nephrotoxicity, neurobehavioural changes, autoimmunity, oxidative stress, autism, skin and mucosa alterations, non-specific symptoms and complaints, Alzheimer's disease, and multiple sclerosis. Both those opposed and those not opposed to dental amalgam recognize that amalgam has been found to be a rare contributor to
Amalgam tattoo Amalgam tattoo Amalgam tattoo (also termed localized argyrosis, or focal argyrosis) is a grey, blue or black area of discoloration on the mucous membranes of the mouth, typically on the gums of the lower jaw. It is an iatrogenic lesion, caused by entry of dental amalgam into the soft tissues. It is common, painless, and benign, but it can be mistaken for melanoma. Amalgam tattoo usually occurs on the mandibular gingiva, often in an area in which a apicoectomy ("root-end filling") with amalgam was carried out. After the gingiva, the alveolar mucosa and the buccal mucosa are the next most