Dental amalgam controversy of mercury released from amalgam restorations, especially during placement and removal, has not been shown to cause any other adverse health effects." The paper goes on to say that there have been "no controlled studies published that show adverse systemic effects" from amalgam restorations and there is no evidence that removing amalgam restorations relieves any general symptoms. More recently, FDI has published a resolution confirming that their position on the safety and effectiveness of amalgam has not changed despite the phasing-down in some countries In the United States, numerous respected professional and non-profit organizations consider amalgam use to be safe
Amalgam (dentistry) by using database in the Cochrane Library where randomized controlled trials of few studies comparing dental resin composite with dental amalgams in permanent posterior teeth were compared. This review supports the fact that amalgam restorations are particularly useful and successful in parts of the world where amalgam is still the material of choice to restore posterior teeth with proximal caries. Though, there is insufficient evidence to support or refute any adverse effects amalgam may have on patients, new research is unlikely to change opinion on its safety and due to the decision for a global phase-down of amalgam (Minamata Convention