Dental amalgam controversy demonstrated that mercury released from amalgam restorations does not give rise to toxic effects on the nervous system of children. More recently, a Cochrane Systematic review in 2014 found, "insufficient evidence to support or refute any adverse effects associated with amalgam or composite restorations." Those opposed to dental amalgam suggest that mercury from dental amalgam may lead to nephrotoxicity, neurobehavioural changes, autoimmunity, oxidative stress, autism, skin and mucosa alterations, non-specific symptoms and complaints, Alzheimer's disease, and multiple sclerosis. Both those opposed and those not opposed to dental amalgam recognize that amalgam has been found to be a rare contributor to
Organosilver chemistry η-alkene complex. Silver is also present in other carbon-carbon bond skeletal rearrangements such as the quadricyclane to norbornadiene rearrangement, the cubane to cuneane rearrangement and the rearrangement of the cyclobutadiene dimer to cyclooctatetraene. Organosilver chemistry Organosilver chemistry in chemistry is the study of organometallic compounds containing a carbon to silver chemical bond and the study of silver as catalyst in organic reactions. In the group 11 elements silver is the element below copper. The chemistries have much in common but organosilver catalysis is much less common (mostly academic study) than organocopper chemistry due both to the relatively high price of