Dental amalgam controversy an increasing number of studies with larger sample sizes are being conducted. Those who are not opposed to amalgam claim that, aside from rare and localized tissue irritation, recent evidence-based research has continued to demonstrate no ill effects from the minute amounts of mercury exposure from amalgam fillings. A 2004 systematic review conducted by the Life Sciences Research Office, whose clients include the FDA and NIH, concluded that, "the current data are insufficient to support an association between mercury release from dental amalgam and the various complaints that have been attributed to this restoration material." A systematic review in 2009
Alchemy and chemistry in medieval Islam that have come down through the years were preserved as Arabic translations. In considering Islamic sciences as a distinct, local practice, it is important to define words such as "Arabic," "Islamic," "alchemy," and "chemistry." In order to gain a better grasp on the concepts discussed in this article, it is important to come to an understanding of what these terms mean historically. This may also help to clear up any misconceptions regarding the possible differences between alchemy and early chemistry in the context of medieval times. As A.I. Sabra writes in his article entitled, "Situating Arabic Science: Location versus Essence,"