Effects of stress on memory from the adrenal gland. These substances are the main factors responsible for the stress response in humans. Cortisol for example stimulates the mobilization of free fatty acids and proteins and the breakdown of amino acids, and increases serum glucose level and blood pressure, among other effects. On the other hand, aldosterone is responsible for water retention associated with stress. As a result of cells retaining sodium and eliminating potassium, water is retained and blood pressure is increased by increasing the blood volume. A second physiological response in relation to stress occurs via the vasopressin axis. Vasopressin, also known as antidiuretic
Ebola virus disease causes swelling and shock due to loss of blood volume. The dysfunctional bleeding and clotting commonly seen in EVD has been attributed to increased activation of the extrinsic pathway of the coagulation cascade due to excessive tissue factor production by macrophages and monocytes. After infection, a secreted glycoprotein, small soluble glycoprotein (sGP or GP) is synthesized. EBOV replication overwhelms protein synthesis of infected cells and the host immune defenses. The GP forms a trimeric complex, which tethers the virus to the endothelial cells. The sGP forms a dimeric protein that interferes with the signaling of neutrophils, another type of white