Type 3c (Pancreatogenic) Diabetes Type 3c (Pancreatogenic) Diabetes Type 3c diabetes (also known as Pancreatogenic diabetes) is a form of diabetes that is being researched. It involves the exocrine and digestive functions of the pancreas. Out of all the diabetics, 5–10% may actually be type 3c diabetics. In 80% of people who suffer from this condition, chronic pancreatitis seems to be the cause. The same complications that occur for other types of diabetics (type 1 and type 2) may occur for type 3c diabetics. These include retinopathy, nephropathy, neuropathy, and cardiovascular disease. Patients with this condition are advised to follow the same risk-reduction guidelines
Epigenetics of diabetes Type 2 indicator of an increased risk of contracting type 2 diabetes. There are a number of genes involved in chromatin methylation. One of these genes encodes the enzyme Methylenetetrahydrofolate reductase (MTHFR). MTHFR is involved in reducing 5,10-methylenetetrahydrofolate to 5-methyltentetrahydrofolate. This reaction is a critical step in the conversion of homocysteine to methionine. The resulting product is a methyl donor that is required for CpG and histone methylation. Mutations in this gene can lead to reduced methylation at CpG sites, and these changes in methylation patterns may increase susceptibility for Type 2 Diabetes. The most common at the gene encoding MTHFR is