Serum sickness proteins to form immune complexes. These complexes precipitate, enter the walls of blood vessels, and activate the complement cascade, initiating an inflammatory response and consuming much of the available complement component 3 (C3). The result is a leukocytoclastic vasculitis. This results in hypocomplementemia, a low C3 level in serum. They can also cause more reactions resulting in typical symptoms of serum sickness. Serum sickness can be developed as a result of exposure to antibodies derived from animals. These sera or antitoxins are generally administered to prevent or treat an infection or envenomation. Some of the drugs associated with serum sickness
Blood, Sweat & 3 Years Blood, Sweat & 3 Years Blood, Sweat & 3 Years is the fourth studio album by American electronic music group Cash Cash, released on June 24, 2016 by Big Beat Records and Atlantic Records. It is their first full-length album since signing to Big Beat, following the release of the "Overtime" and "Lightning" EPs. "Blood, Sweat & 3 Years" includes collaborations with singers Anjulie, Bebe Rexha, Chrish, Christina Perri, Dev, Jacquie Lee, Jenna Andrews, John Rzeznik from the Goo Goo Dolls, Julia Michaels, Michael Fitzpatrick of Fitz and The Tantrums, Neon Hitch, and Sofia Reyes; rappers B.o.B, Busta Rhymes, Nelly,