Apium virus Y sea celery ("Apium prostratum"), cilantro ("Coriandrum sativum"), and bishop’s weed ("Ammi majus"). In Germany it has recently been found naturally infecting celeriac or celery root. All are members of the plant family "Apiaceae". Symptoms reported included mosaic, vein clearing or banding, necrotic/chlorotic line patterns and stunting. Some samples of parsley, celery and poison hemlock, that gave positive results in tests, however, were asymptomatic. In host range studies, the virus causes local lesions on "Chenopodium quinoa" and "C. amaraticolor" ("Amaranthaceae"). Apium virus Y "Apium virus Y" (ApVY) is a plant pathogenic virus in the genus "Potyvirus" and the virus family "Potyviridae".
Family with sequence similarity 111 member a Family with sequence similarity 111 member a Family with sequence similarity 111 member A is a protein that in humans is encoded by the FAM111A gene. The protein encoded by this gene is cell-cycle regulated, and has nuclear localization. The C-terminal half of the protein shares homology with trypsin-like peptidases and it contains a PCNA-interacting peptide (PIP) box, that is necessary for its co-localization with proliferating cell nuclear antigen (PCNA). Reduced expression of this gene resulted in DNA replication defects, consistent with the demonstrated role for this gene in Simian Virus 40 (SV40) viral replication. Mutations in this gene have