Cobalt chelatase Cobalt chelatase Cobalt chelatase () is an enzyme that catalyzes the chemical reaction The 4 substrates of this enzyme are ATP, hydrogenobyrinic acid a,c-diamide, Co, and HO, whereas its 4 products are ADP, phosphate, cob(II)yrinic acid a,c-diamide, and H. The aerobic cobalt chelatase (aerobic cobalamin biosynthesis pathway) consists of three subunits, CobT, CobN () and CobS (). Cobalamin (vitamin B12) can be complexed with metal via the ATP-dependent reactions (aerobic pathway) (e.g., in "Pseudomonas denitrificans") or via ATP-independent reactions (anaerobic pathway) (e.g., in "Salmonella typhimurium"). The corresponding cobalt chelatases are not homologous. However, aerobic cobalt chelatase subunits CobN and CobS
Chemical element neutrons) for a particular isotope of an element, with this number combined with the pertinent element's symbol. IUPAC prefers that isotope symbols be written in superscript notation when practical, for example C and U. However, other notations, such as carbon-12 and uranium-235, or C-12 and U-235, are also used. As a special case, the three naturally occurring isotopes of the element hydrogen are often specified as H for H (protium), D for H (deuterium), and T for H (tritium). This convention is easier to use in chemical equations, replacing the need to write out the mass number for each atom.