Proper velocity by Hermann Minkowski's flat-space metric equation . Here a reference map frame of yardsticks and synchronized clocks define map position x and map time "t" respectively, and the "d" preceding a coordinate means infinitesimal change. A bit of manipulation allows one to show that proper velocity where as usual coordinate velocity . Thus finite "w" ensures that "v" is less than lightspeed "c". By grouping "γ" with v in the expression for relativistic momentum p, proper velocity also extends the Newtonian form of momentum as mass times velocity to high speeds without a need for relativistic mass. The proper velocity
N,N-Dimethyltryptamine (step 1). The resulting decarboxylated tryptophan analog is tryptamine. Tryptamine then undergoes a transmethylation (step 2): the enzyme indolethylamine-N-methyltransferase (INMT) catalyzes the transfer of a methyl group from cofactor S-adenosyl-methionine (SAM), via nucleophilic attack, to tryptamine. This reaction transforms SAM into S-adenosylhomocysteine (SAH), and gives the intermediate product "N"-methyltryptamine (NMT). NMT is in turn transmethylated by the same process (step 3) to form the end product "N","N"-dimethyltryptamine. Tryptamine transmethylation is regulated by two products of the reaction: SAH, and DMT were shown "ex vivo" to be among the most potent inhibitors of rabbit INMT activity. This transmethylation mechanism has been