Cardiovascular disease strategies. A 2015 Cochrane Review found some evidence that interventions aiming to reduce more than one cardiovascular risk factor may have beneficial effects on blood pressure, body mass index and waist circumference; however, evidence was limited and the authors were unable to draw firm conclusions on the effects on cardiovascular events and mortality. For adults without a known diagnosis of hypertension, diabetes, hyperlipidemia, or cardiovascular disease, routine counseling to advise them to improve their diet and increase their physical activity has not been found to significantly alter behavior, and thus is not recommended. Another Cochrane review suggested that simply providing
Salt and cardiovascular disease of sodium sensitivity. The influence of physiological factors including renal function and insulin levels on sodium sensitivity are shown in various studies. One study concludes that the effect of renal failure on sodium sensitivity is substantial due to the contribution of decreasing the Glomerular filtration rate (GFR) in the kidney. Moreover, insulin resistance is found to be related to sodium sensitivity; however, the actual mechanism is still unknown. Possible mechanisms by which high intakes of dietary potassium can decrease risk of hypertension and instances of cardiovascular disease have been proposed but not extensively studied. However, studies have found a strong