Grasshopper escapement to Harrison were poor, messy and short-lived. This meant that conventional clocks had to be stopped frequently for cleaning and oiling. Using his clean and absolutely stable grasshopper escapement Harrison began a series of long-term investigations into the performance of clocks, leading to his invention of the gridiron pendulum which counteracted the effects of expansion and contraction with changing temperature. The performance of his improved clocks in turn gave him an accurate, convenient standard against which to test his marine timekeepers. Harrison developed the grasshopper escapement from a conventional anchor escapement which he built for a turret clock to go
Controlled internal drug release Controlled internal drug release Controlled internal drug release (CIDR) devices are used in livestock for the synchronization of estrus. They are T-shaped devices with a silicone-coated nylon core. The silicone coating is impregnated with progesterone. CIDRs are inserted intra-vaginally using a specialized applicator. The flexible wings collapse for facilitated insertion and expand once placed appropriately within the vagina. The expansion of the wings retains its position; CIDRs have very high retention rates that may exceed 97%. A thin nylon tail remains exteriorized and is used for removal. Once inserted, CIDRs provide slow-release administration of progesterone, which artificially extends the luteal