Glycyrrhizin an increase in blood pressure, may cause irregular heart rhythm, and adverse interactions with prescription medicines. The effects on body fluids are related to the inhibition of cortisol metabolism within the kidney, subsequent stimulation of the mineralocorticoid receptors, and decrease in blood levels of renin, potassium, and aldosterone, which collectively lead to increases in blood pressure. Depending on amount and frequency of ingesting black licorice, other side effects may include: Glycyrrhizin is under laboratory and preliminary clinical research for its possible activity against common viruses, such as hepatitis C. In vitro, glycyrrhizin inhibits the enzyme 11β-hydroxysteroid dehydrogenase. After oral ingestion,
Cyanea glabra hawaiiense", "Pipturus albidus", "Coprosma" spp., "Wikstroemia oahuensis", "Clermontia kakeana", "Psychotria" spp., "Sadleria" spp., "Cyrtandra spathulata", "Touchardia latifolia", "Freycinetia arborea", and "Cyanea elliptica". The remaining 12 plants are part of one population divided into two subpopulations. Threats to the species include exotic plants, feral pigs, and landslides. Cyanea glabra Cyanea glabra is a rare species of flowering plant in the bellflower family known by the common name smooth cyanea. It is endemic to Maui, where there are twelve plants remaining in the wild. It was federally listed as an endangered species of the United States with nine other Maui Nui endemics