Immune tolerance the resulting effect is similar. Immune tolerance is important for normal physiology. Central tolerance is the main way the immune system learns to discriminate self from non-self. Peripheral tolerance is key to preventing over-reactivity of the immune system to various environmental entities (allergens, gut microbes, etc.). Deficits in central or peripheral tolerance also cause autoimmune disease, resulting in syndromes such as systemic lupus erythematosus, rheumatoid arthritis, type 1 diabetes, autoimmune polyendocrine syndrome type 1 (APS-1), and immunodysregulation polyendocrinopathy enteropathy X-linked syndrome (IPEX), and potentially contribute to asthma, allergy, and inflammatory bowel disease. And immune tolerance in pregnancy is what allows
Central nervous system disease a problem with cellular division. Problems with the body's immune system can lead to tumors. An autoimmune disorder is a condition where in the immune system attacks and destroys healthy body tissue. This is caused by a loss of tolerance to proteins in the body, resulting in immune cells recognising these as 'foreign' and directing an immune response against them. A stroke is an interruption of the blood supply to the brain. Approximately every 40 seconds, someone in the US has a stroke. This can happen when a blood vessel is blocked by a blood clot or when a blood