Glycyrrhizin an increase in blood pressure, may cause irregular heart rhythm, and adverse interactions with prescription medicines. The effects on body fluids are related to the inhibition of cortisol metabolism within the kidney, subsequent stimulation of the mineralocorticoid receptors, and decrease in blood levels of renin, potassium, and aldosterone, which collectively lead to increases in blood pressure. Depending on amount and frequency of ingesting black licorice, other side effects may include: Glycyrrhizin is under laboratory and preliminary clinical research for its possible activity against common viruses, such as hepatitis C. In vitro, glycyrrhizin inhibits the enzyme 11β-hydroxysteroid dehydrogenase. After oral ingestion,
Sweet Medicine Sweet Medicine Sweet Medicine is an ITV drama series from 2003 about a family doctor's surgery in the Peak District of central England. Intended as a replacement for the hit medical drama "Peak Practice", it was not a success. Only one ten-episode series was made, despite moderate audience figures. Some viewers considered it too raunchy, especially for a 9:00pm broadcast. The majority of filming took place in the historic market town of Wirksworth, which made the set for the fictional Derbyshire town of Stoneford. "Sweet Medicine" starred Patricia Hodge as Georgina Sweet, Jason Merrells as Dr. Nicholas Sweet and Gillian