Glycyrrhizin an increase in blood pressure, may cause irregular heart rhythm, and adverse interactions with prescription medicines. The effects on body fluids are related to the inhibition of cortisol metabolism within the kidney, subsequent stimulation of the mineralocorticoid receptors, and decrease in blood levels of renin, potassium, and aldosterone, which collectively lead to increases in blood pressure. Depending on amount and frequency of ingesting black licorice, other side effects may include: Glycyrrhizin is under laboratory and preliminary clinical research for its possible activity against common viruses, such as hepatitis C. In vitro, glycyrrhizin inhibits the enzyme 11β-hydroxysteroid dehydrogenase. After oral ingestion,
Pontefract Monkhill railway station Pontefract Monkhill railway station Pontefract Monkhill railway station is the busiest station in the town of Pontefract, West Yorkshire, England. The station is on the Pontefract Line managed by Northern but is also served by Grand Central and is south east of Leeds. The other stations in the town are Pontefract Tanshelf and Pontefract Baghill. The lines to Leeds via Castleford and Wakefield Kirkgate separate immediately west of the station, which was opened by the "Wakefield, Pontefract & Goole Railway" (one of the constituent companies of the Lancashire and Yorkshire Railway) in April 1848. The branch to Castleford (Cutsyke) &