Escapement between the balance wheel and the escape wheel; this is the form used in modern watches. In 1867 Georges Frederic Roskopf invented an inexpensive, less accurate form called the Roskopf or pin-pallet escapement, which was used in cheap "dollar watches" in the early 20th century and is still used in cheap alarm clocks and kitchen timers. A rare but interesting mechanical escapement is John Harrison's grasshopper escapement invented in 1722. In this escapement, the pendulum is driven by two hinged arms (pallets). As the pendulum swings, the end of one arm catches on the escape wheel and drives it slightly
Osmotic-controlled release oral delivery system Osmotic-controlled release oral delivery system The osmotic-controlled release oral delivery system (OROS) is an advanced controlled release oral drug delivery system in the form of a rigid tablet with a semi-permeable outer membrane and one or more small laser drilled holes in it. As the tablet passes through the body, water is absorbed through the semipermeable membrane via osmosis, and the resulting osmotic pressure is used to push the active drug through the opening(s) in the tablet. OROS is a trademarked name owned by ALZA Corporation, which pioneered the use of osmotic pumps for oral drug delivery. Osmotic release systems