Mannan-binding lectin the body. It is produced in the liver as a response to infection, and is part of many other factors termed acute phase proteins. Expression and function in other organs were also suggested. The three structural polymorphisms of exon 1 have been reported to cause susceptibility to various common infections, including meningococcal disease. However, evidence has been presented that suggests no harmful effect of these variants with regard to mengingococcal disease. Mannan-binding lectin Mannose-binding lectin (MBL), also called mannose-binding protein or mannan-binding protein (MBP), is a lectin that is instrumental in innate immunity via the lectin pathway. MBL has an
Keratin 6A encoded by separate genes located within the type II keratin gene cluster on human chromosome 12q. It is found with keratin 16 and/or keratin 17 in the palm and sole epidermis, the epithelial cells of the nail bed, the filiform papillae of the tongue, the epithelial lining of oral mucosa and esophagus, as well as the hair follicles. This keratin 6 isoform is thought to be the most abundant of the K6 isoforms. The "KRT6A" gene consists of 9 exons separated by 8 introns and is located in the type II keratin gene cluster on human "chromosome" 12q. Keratin 6B