Anchor escapement clocks with 1 meter (39 inch) seconds pendulums that came to be called longcase or 'grandfather' clocks. The anchor increased the accuracy of clocks so much that around 1680–1690 the use of the minute hand, formerly the exception in clocks, became the rule. The anchor escapement replaced the verge in pendulum clocks within about fifty years, although French clockmakers continued to use verges until about 1800. Many verge clocks were rebuilt with anchors. In the 18th century the more accurate deadbeat form of the escapement replaced the anchor in precision regulators, but the anchor remained the workhorse in home pendulum
Osmotic-controlled release oral delivery system separate drug layers with different concentrations of methylphenidate in addition to the (now quite robust) push layer. OROS medications include: Osmotic-controlled release oral delivery system The osmotic-controlled release oral delivery system (OROS) is an advanced controlled release oral drug delivery system in the form of a rigid tablet with a semi-permeable outer membrane and one or more small laser drilled holes in it. As the tablet passes through the body, water is absorbed through the semipermeable membrane via osmosis, and the resulting osmotic pressure is used to push the active drug through the opening(s) in the tablet. OROS is a