Glycyrrhizin an increase in blood pressure, may cause irregular heart rhythm, and adverse interactions with prescription medicines. The effects on body fluids are related to the inhibition of cortisol metabolism within the kidney, subsequent stimulation of the mineralocorticoid receptors, and decrease in blood levels of renin, potassium, and aldosterone, which collectively lead to increases in blood pressure. Depending on amount and frequency of ingesting black licorice, other side effects may include: Glycyrrhizin is under laboratory and preliminary clinical research for its possible activity against common viruses, such as hepatitis C. In vitro, glycyrrhizin inhibits the enzyme 11β-hydroxysteroid dehydrogenase. After oral ingestion,
Pontefract with Leeds and Wakefield. There are also rail services from Bradford to London that stop at Pontefract Monkhill. The local police force is West Yorkshire Police, with the town's neighbourhood policing team being situated at the new fire station on Stumpcross Lane. The original police station situated in Sessions House yard is due for closure since the new divisional headquarters for the Wakefield District opened in Normanton and the neighbouring magistrates' court has moved over to Wakefield. Fire cover is provided by West Yorkshire Fire and Rescue with one pump (sometimes two) based at Pontefract Fire Station. Formerly located on