Glycyrrhizin an increase in blood pressure, may cause irregular heart rhythm, and adverse interactions with prescription medicines. The effects on body fluids are related to the inhibition of cortisol metabolism within the kidney, subsequent stimulation of the mineralocorticoid receptors, and decrease in blood levels of renin, potassium, and aldosterone, which collectively lead to increases in blood pressure. Depending on amount and frequency of ingesting black licorice, other side effects may include: Glycyrrhizin is under laboratory and preliminary clinical research for its possible activity against common viruses, such as hepatitis C. In vitro, glycyrrhizin inhibits the enzyme 11β-hydroxysteroid dehydrogenase. After oral ingestion,
Carya glabra hickory is an important shade tree in wooded suburban areas over most of the range but is seldom planted as an ornamental tree because of its size and difficulty of transplanting, although it has spectacular orangey-red fall colors. "Carya glabra" var. "megacarpa" (Sarg.) Sarg., coast pignut hickory, was once recognized as a distinct variety but is now considered to be a synonym of "C. glabra" (Mill.) Sweet. "C. leiodermis" Sarg., swamp hickory, has also been added as a synonym of "C. glabra" (11). "Carya glabra" (Mill.) Sweet var. "glabra" distinguishes the (typical) pignut hickory from red hickory ("C. glabra" var.