Yorkshire Liquorice sweet was first created by George Dunhill from Pontefract, who in the 1760s thought to mix the liquorice plant with sugar. Yorkshire and in particular the city of York played a prominent role in the confectionery industry, with chocolate factories owned by companies such as Rowntree's, Terry's and Thorntons inventing many of Britain's most popular sweets. Another traditional Yorkshire food is pikelets, which are similar to crumpets but much thinner. The Rhubarb Triangle is a location within Yorkshire which supplies most of the rhubarb to locals. In recent years curries have become popular in the county, largely due to
Glycyrrhizin glycyrrhizin is first hydrolysed to 18β-glycyrrhetinic acid (enoxolone) by intestinal bacteria. After complete absorption from the gut, 18β-glycyrrhetinic acid is metabolised to 3β-monoglucuronyl-18β-glycyrrhetinic acid in the liver. This metabolite then circulates in the bloodstream. Consequently, its oral bioavailability is poor. The main part is eliminated by bile and only a minor part (0.31–0.67%) by urine. After oral ingestion of 600 mg of glycyrrhizin the metabolite appeared in urine after 1.5 to 14 hours. Maximal concentrations (0.49 to 2.69 mg/l) were achieved after 1.5 to 39 hours and metabolite can be detected in the urine after 2 to 4 days. Glycyrrhizin