Mannan-binding lectin the body. It is produced in the liver as a response to infection, and is part of many other factors termed acute phase proteins. Expression and function in other organs were also suggested. The three structural polymorphisms of exon 1 have been reported to cause susceptibility to various common infections, including meningococcal disease. However, evidence has been presented that suggests no harmful effect of these variants with regard to mengingococcal disease. Mannan-binding lectin Mannose-binding lectin (MBL), also called mannose-binding protein or mannan-binding protein (MBP), is a lectin that is instrumental in innate immunity via the lectin pathway. MBL has an
Myosin head although some forms have a globular region in their C-terminal. There are many cell-specific isoforms of myosin heavy chains, coded for by a multi-gene family. Myosin interacts with actin to convert chemical energy, in the form of ATP, to mechanical energy. The 3-D structure of the head portion of myosin has been determined and a model for actin-myosin complex has been constructed. The globular head is well conserved, and is key to contraction. Muscle contraction results from an attachment–detachment cycle between the myosin heads extending from myosin filaments and the sites on actin filaments. The myosin head first attaches to