Loose connective tissue skin and mucous membranes, it is more compact and sometimes difficult to distinguish from dense irregular connective tissue. Areolar connective tissues hold organs in place and attaches epithelial tissue to other underlying tissues. It also serves as a reservoir of water and salts for surrounding tissues. Almost all cells obtain their nutrients from and release their wastes into areolar connective tissue. Organs that are rich in loose connective tissue(such as the eyelids) are usually sites that undergo oedema indicating renal failure or nephrotic syndrome. Thus periorbital swelling is one characteristic finding in severe renal disease Loose connective tissue Loose connective
Cerebral edema include physical disruption by arterial hypertension or trauma, and tumor-facilitated release of vasoactive and endothelial destructive compounds (e.g. arachidonic acid, excitatory neurotransmitters, eicosanoids, bradykinin, histamine, and free radicals). Subtypes of vasogenic edema include: In cytotoxic edema, the blood–brain barrier remains intact but a disruption in cellular metabolism impairs functioning of the sodium and potassium pump in the glial cell membrane, leading to cellular retention of sodium and water. Swollen astrocytes occur in gray and white matter. Cytotoxic edema is seen with various toxins, including dinitrophenol, triethyltin, hexachlorophene, and isoniazid. It can occur in Reye's syndrome, severe hypothermia, early ischemia, encephalopathy,