Spinal cord injury research triggering an immune system response. Animal studies with injection of bone marrow stem cells have shown improvement in motor function; however not so in a human trial a year post-injury. More trials are underway. Adipose and umbilical tissue stem cells need further study before human trials can be performed, but two Korean studies were begun to investigate adipose cells in SCI patients. Transplantation of tissues such as olfactory ensheathing cells from the olfactory bulbs has been shown to produce beneficial effects in spinal cord injured rats. Trials have also begun to show success when olfactory ensheathing cells are transplanted into
Spinal cord injury about the T12–L2 vertebrae in adults. This region contains the S4–S5 spinal segments, responsible for bowel, bladder, and some sexual functions, so these can be disrupted in this type of injury. In addition, sensation and the Achilles reflex can be disrupted. Causes include tumors, physical trauma, and ischemia. Cauda equina syndrome (CES) results from a lesion below the level at which the spinal cord splits into the cauda equina, at levels L2–S5 below the conus medullaris. Thus it is not a true spinal cord syndrome since it is nerve roots that are damaged and not the cord itself; however it