Glycyrrhizin an increase in blood pressure, may cause irregular heart rhythm, and adverse interactions with prescription medicines. The effects on body fluids are related to the inhibition of cortisol metabolism within the kidney, subsequent stimulation of the mineralocorticoid receptors, and decrease in blood levels of renin, potassium, and aldosterone, which collectively lead to increases in blood pressure. Depending on amount and frequency of ingesting black licorice, other side effects may include: Glycyrrhizin is under laboratory and preliminary clinical research for its possible activity against common viruses, such as hepatitis C. In vitro, glycyrrhizin inhibits the enzyme 11β-hydroxysteroid dehydrogenase. After oral ingestion,
Pontefract Collieries F.C. Pontefract Collieries F.C. Pontefract Collieries Football Club are a football club based in Pontefract, West Yorkshire, England. The team plays in the . Pontefract Collieries is affiliated to the West Riding County Football Association and Castleford & District Football Association. They have historic local rivalries with neighbours Glasshoughton Welfare and Selby Town. In recent times, a rivalry with Hemsworth Miners Welfare also developed when the clubs played in the same division. Pontefract Collieries play their home games at The Harratts Nissan Stadium, Pontefract, sometimes known as Beechnut Lane due to the access road, situated near to the site of the