Pontefract Pontefract and Castleford, referred to locally as 'Cas Vegas'. It is reported that Pontefract once held the British record for the town with the most pubs per square mile: indeed, numerous pubs still survive in the town centre in particular, for example Beastfair Vaults, the Liquorice Bush, the Red Lion, the Malt Shovel and the Blackmoor Head. A Wetherspoon public house opened on Horsefair in 2010. Pontefract's deep, sandy soil makes it one of the few British places in which liquorice can successfully be grown. The town has a liquorice-sweet industry; and the famous Pontefract cakes are produced, though the
Glycyrrhizin glycyrrhizin is first hydrolysed to 18β-glycyrrhetinic acid (enoxolone) by intestinal bacteria. After complete absorption from the gut, 18β-glycyrrhetinic acid is metabolised to 3β-monoglucuronyl-18β-glycyrrhetinic acid in the liver. This metabolite then circulates in the bloodstream. Consequently, its oral bioavailability is poor. The main part is eliminated by bile and only a minor part (0.31–0.67%) by urine. After oral ingestion of 600 mg of glycyrrhizin the metabolite appeared in urine after 1.5 to 14 hours. Maximal concentrations (0.49 to 2.69 mg/l) were achieved after 1.5 to 39 hours and metabolite can be detected in the urine after 2 to 4 days. Glycyrrhizin