Glycyrrhizin an increase in blood pressure, may cause irregular heart rhythm, and adverse interactions with prescription medicines. The effects on body fluids are related to the inhibition of cortisol metabolism within the kidney, subsequent stimulation of the mineralocorticoid receptors, and decrease in blood levels of renin, potassium, and aldosterone, which collectively lead to increases in blood pressure. Depending on amount and frequency of ingesting black licorice, other side effects may include: Glycyrrhizin is under laboratory and preliminary clinical research for its possible activity against common viruses, such as hepatitis C. In vitro, glycyrrhizin inhibits the enzyme 11β-hydroxysteroid dehydrogenase. After oral ingestion,
Sarcandra glabra and other places, growing at an altitude of 420 meters to 1,500 meters in area, often grown in wet slopes and valleys of the forest shade. It has not yet been cultivated by artificial introduction. "Nine-knotted flower," "bone-knitted lotus." Sarcandra glabra "Sarcandra glabra" is an herb native to Southeast Asia. It is also known as herba sarcandrae or glabrous sarcandra herb. Aromatic oils may be extracted from the leaves. The entire plant has anti-stress, antioxidant, anti-inflammatory, detoxifying, blood activating, and anti-bacterial effects. Leaf blade elliptic or ovate-lanceolate, 6–17 × 2–6 cm, leathery, margin sharply coarsely-serrate. Stamen baculate to terete; thecae