Isotope …, "m" are the atomic masses of each individual isotope, and "x", …, "x" are the relative abundances of these isotopes. Several applications exist that capitalize on properties of the various isotopes of a given element. Isotope separation is a significant technological challenge, particularly with heavy elements such as uranium or plutonium. Lighter elements such as lithium, carbon, nitrogen, and oxygen are commonly separated by gas diffusion of their compounds such as CO and NO. The separation of hydrogen and deuterium is unusual because it is based on chemical rather than physical properties, for example in the Girdler sulfide process.
Relative atomic mass definitions (as taken from the "Gold Book") are: and Here the "unified atomic mass unit" refers to of the mass of an atom of C "in its ground state". The IUPAC definition of relative atomic mass is: The definition deliberately specifies "An atomic weight…", as an element will have different relative atomic masses depending on the source. For example, boron from Turkey has a lower relative atomic mass than boron from California, because of its different isotopic composition. Nevertheless, given the cost and difficulty of isotope analysis, it is common practice to instead substitute the tabulated values of standard atomic