Pontefract cake Pontefract cake Pontefract cakes (also known as Pomfret cakes and Pomfrey cakes) are a type of small, roughly circular black sweet measuring approximately 2 cm in diameter and 4 mm thick, made of liquorice, originally manufactured in the Yorkshire town of Pontefract, England. The original name for these small tablets of liquorice is a "Pomfret" cake, after the old Norman name for Pontefract. However, that name has fallen into disuse and they are now almost invariably labelled "Pontefract cakes". The term "cake" has a long history. The word itself is of Germanic origin, from the Germanic "kakâ" (cook). The exact
Glycyrrhizin glycyrrhizin is first hydrolysed to 18β-glycyrrhetinic acid (enoxolone) by intestinal bacteria. After complete absorption from the gut, 18β-glycyrrhetinic acid is metabolised to 3β-monoglucuronyl-18β-glycyrrhetinic acid in the liver. This metabolite then circulates in the bloodstream. Consequently, its oral bioavailability is poor. The main part is eliminated by bile and only a minor part (0.31–0.67%) by urine. After oral ingestion of 600 mg of glycyrrhizin the metabolite appeared in urine after 1.5 to 14 hours. Maximal concentrations (0.49 to 2.69 mg/l) were achieved after 1.5 to 39 hours and metabolite can be detected in the urine after 2 to 4 days. Glycyrrhizin