Mixed connective tissue disease connective tissue disease is not necessarily associated with serum antibodies directed against the U1-RNP, and MCTD is associated with a more clearly defined set of signs/symptoms. MCTD combines features of scleroderma, myositis, systemic lupus erythematosus, and rheumatoid arthritis (with some sources adding polymyositis, dermatomyositis, and inclusion body myositis) and is thus considered an overlap syndrome. MCTD commonly causes: It has been associated with HLA-DR4. Distinguishing laboratory characteristics are a positive, speckled anti-nuclear antibody and an anti-U1-RNP antibody. The prognosis of mixed connective tissue disease is in one third of cases worse than that of systemic lupus erythematosus (SLE). In spite
Autologous immune enhancement therapy and destruction. While surgery and/or chemo- and radiotherapies are various treatment modalities available, still in many cases they don’t offer a permanent cure. Another major point to be addressed about this killer disease is the relapse rate which is very high. Researchers have found that these cells mainly target the cancer cells and not the healthy cells whereas in chemotherapy and radiotherapy the healthy cells are also getting destroyed. Cancer cells are formed in our body almost every day but we are not affected by them. This is because they are immediately destroyed by the body's immune system. The immune