Public Health Emergency of International Concern second PHEIC was issued in May 2014 with the resurgence of polio after its near-eradication, deemed "an extraordinary event." On Friday, August 8, 2014, the World Health Organization declared its third Public Health Emergency of International Concern in response to the outbreak of Ebola in Western Africa. On Monday, February 1, 2016, the World Health Organization declared its fourth PHEIC in response to clusters of microcephaly and Guillain–Barré syndrome in the Americas, which at the time were suspected to be associated with the ongoing outbreak of Zika virus. Later research and evidence bore out these concerns; in April, the WHO
World Health Organization the Vienna Philharmonic Orchestra) and a further ambassador associated with a partnership project (Craig David). The World Health Organization operates 150 country offices in six different regions. It also operates several liaison offices, including those with the European Union, United Nations and a single office covering the World Bank and International Monetary Fund. It also operates the International Agency for Research on Cancer in Lyon, France, and the WHO Centre for Health Development in Kobe, Japan. Additional offices include those in Pristina; the West Bank and Gaza; the US-Mexico Border Field Office in El Paso; the Office of the Caribbean