Pungi fifty years ago. However, prior to this it derived from Indian folk music and was used for religious purposes for snake charming. The pungi is traditionally made from a dried bottle gourd. Often, the neck of the gourd is carved for aesthetic reasons. On the other end, two (sometimes one or three) reed or bamboo pipes are connected. These are known as the "jivala". One of the pipes has 5 - 9 holes and plays the melody; the other pipe is for drone. The jivala is fitted to the gourd with beeswax, which can be adjusted for pitch modification. The
Activity-regulated cytoskeleton-associated protein Activity-regulated cytoskeleton-associated protein Activity-regulated cytoskeleton-associated protein is a plasticity protein that in humans is encoded by the ARC gene. It was first characterized in 1995. Arc is a member of the immediate-early gene (IEG) family, a rapidly activated class of genes functionally defined by their ability to be transcribed in the presence of protein synthesis inhibitors. Arc mRNA is localized to activated synaptic sites in an NMDA receptor-dependent manner, where the newly translated protein is believed to play a critical role in learning and memory-related molecular processes. Arc is widely considered to be an important protein in neurobiology because of