Anchor escapement his precision regulator clocks. However it was actually invented around 1675 by astronomer Richard Towneley, and first used by Graham's mentor Thomas Tompion in a clock built for Sir Jonas Moore, and in the two precision regulators he made for the new Greenwich Observatory in 1676, mentioned in correspondence between Astronomer Royal John Flamsteed and Towneley The deadbeat form of the anchor escapement is less tolerant of inaccuracy in its manufacture or wear during operation and was initially used only in precision clocks, but its use spread during the 19th century to most quality pendulum clocks. Almost all pendulum clocks
Osmotic-controlled release oral delivery system separate drug layers with different concentrations of methylphenidate in addition to the (now quite robust) push layer. OROS medications include: Osmotic-controlled release oral delivery system The osmotic-controlled release oral delivery system (OROS) is an advanced controlled release oral drug delivery system in the form of a rigid tablet with a semi-permeable outer membrane and one or more small laser drilled holes in it. As the tablet passes through the body, water is absorbed through the semipermeable membrane via osmosis, and the resulting osmotic pressure is used to push the active drug through the opening(s) in the tablet. OROS is a