Reproductive isolation from a cross between a horse and a donkey or between a mare and a donkey, respectively. These animals are nearly always sterile due to the difference in the number of chromosomes between the two parent species. Both horses and donkeys belong to the genus "Equus", but "Equus caballus" has 64 chromosomes, while "Equus asinus" only has 62. A cross will produce offspring (mule or hinny) with 63 chromosomes, that will not form pairs, which means that they do not divide in a balanced manner during meiosis. In the wild, the horses and donkeys ignore each other and do not
Equus lambei horse, not an ass. The closest resemblance to "E." "lambei" is shown by the Mongolian horse, "E. caballus przewalskii", now believed to be extinct in the wild. In size and proportions, "E. lambei" resembles "E. caballus przewalskii". Among living horses, perhaps the Yukon horse most closely resembles the Przewalski's horse ("Equus caballus przewalskii") from Mongolia . The upper foot bones (metapodials) of "Equus lambei" are slender compared to Przewalski's horse. The bones of "E. lambei" also closely resemble the proximal phalanges of "E. caballus lenensis", an extinct species from the late Pleistocene of Siberia . Along with steppe bison ("Bison