Public Health Emergency of International Concern second PHEIC was issued in May 2014 with the resurgence of polio after its near-eradication, deemed "an extraordinary event." On Friday, August 8, 2014, the World Health Organization declared its third Public Health Emergency of International Concern in response to the outbreak of Ebola in Western Africa. On Monday, February 1, 2016, the World Health Organization declared its fourth PHEIC in response to clusters of microcephaly and Guillain–Barré syndrome in the Americas, which at the time were suspected to be associated with the ongoing outbreak of Zika virus. Later research and evidence bore out these concerns; in April, the WHO
2018 Équateur province Ebola outbreak were suspected of having died from EVD near the town of Bikoro in the Province of Équateur. The World Health Organization declared the outbreak after two people were confirmed as having the disease. On 17 May, the virus was confirmed to have spread to the inland port city of Mbandaka, causing the WHO to raise its assessment of the national risk level to "very high", but not yet to constitute an international public health emergency. The WHO declared the outbreak over on July 24. Subsequent to this, 2018 Kivu Democratic Republic of the Congo Ebola virus outbreak was confirmed in