Verge escapement as the flow of liquid in water clocks, to repetitive, oscillatory processes, such as the swing of pendulums, which had the potential to be more accurate. Oscillating timekeepers are used in all modern timepieces. The verge escapement dates from 13th-century Europe, where its invention led to the development of the first all-mechanical clocks. Starting in the 13th century, large tower clocks were built in European town squares, cathedrals, and monasteries. They kept time by using the verge escapement to drive the foliot, a primitive type of balance wheel, causing it to oscillate back and forth. The foliot was a horizontal
Osmotic-controlled release oral delivery system separate drug layers with different concentrations of methylphenidate in addition to the (now quite robust) push layer. OROS medications include: Osmotic-controlled release oral delivery system The osmotic-controlled release oral delivery system (OROS) is an advanced controlled release oral drug delivery system in the form of a rigid tablet with a semi-permeable outer membrane and one or more small laser drilled holes in it. As the tablet passes through the body, water is absorbed through the semipermeable membrane via osmosis, and the resulting osmotic pressure is used to push the active drug through the opening(s) in the tablet. OROS is a