Glycyrrhizin an increase in blood pressure, may cause irregular heart rhythm, and adverse interactions with prescription medicines. The effects on body fluids are related to the inhibition of cortisol metabolism within the kidney, subsequent stimulation of the mineralocorticoid receptors, and decrease in blood levels of renin, potassium, and aldosterone, which collectively lead to increases in blood pressure. Depending on amount and frequency of ingesting black licorice, other side effects may include: Glycyrrhizin is under laboratory and preliminary clinical research for its possible activity against common viruses, such as hepatitis C. In vitro, glycyrrhizin inhibits the enzyme 11β-hydroxysteroid dehydrogenase. After oral ingestion,
King's School, Pontefract King's School, Pontefract The King's School is a coeducational secondary school with academy status, located in Pontefract, West Yorkshire, England. It is one of the four oldest schools in Yorkshire, dating from 1139 and was refounded by King Edward VI in 1548. King's School Pontefract was founded in 1139. Little documentation survives from its early years, and it was refounded in the reign of King Edward VI. It has been associated with the Duchy of Lancaster since 1588 when it was given an endowment to allow it to continue functioning. In 1792 it was refounded yet again by George III