Escapement which slowly replaced the anchor in precision clocks. The Graham or deadbeat escapement was an improvement of the anchor escapement first made by Thomas Tompion to a design by Richard Towneley in 1675 although it is often credited to Tompion's successor George Graham who popularized it in 1715. In the anchor escapement the swing of the pendulum pushes the escape wheel backward during part of its cycle. This 'recoil' disturbs the motion of the pendulum, causing inaccuracy, and reverses the direction of the gear train, causing backlash and introducing high loads into the system, leading to friction and wear. The
Osmotic-controlled release oral delivery system separate drug layers with different concentrations of methylphenidate in addition to the (now quite robust) push layer. OROS medications include: Osmotic-controlled release oral delivery system The osmotic-controlled release oral delivery system (OROS) is an advanced controlled release oral drug delivery system in the form of a rigid tablet with a semi-permeable outer membrane and one or more small laser drilled holes in it. As the tablet passes through the body, water is absorbed through the semipermeable membrane via osmosis, and the resulting osmotic pressure is used to push the active drug through the opening(s) in the tablet. OROS is a