Mass in special relativity (including the kinetic energy of the gas) only when it is measured in the center of momentum frame. Just as is the case for single particles, the calculated "rest mass" of such a container of gas does not change when it is in motion, although its "relativistic mass" does change. The container may even be subjected to a force which gives it an overall velocity, or else (equivalently) it may be viewed from an inertial frame in which it has an overall velocity (that is, technically, a frame in which its center of mass has a velocity). In this case,
N,N-Dimethyltryptamine (step 1). The resulting decarboxylated tryptophan analog is tryptamine. Tryptamine then undergoes a transmethylation (step 2): the enzyme indolethylamine-N-methyltransferase (INMT) catalyzes the transfer of a methyl group from cofactor S-adenosyl-methionine (SAM), via nucleophilic attack, to tryptamine. This reaction transforms SAM into S-adenosylhomocysteine (SAH), and gives the intermediate product "N"-methyltryptamine (NMT). NMT is in turn transmethylated by the same process (step 3) to form the end product "N","N"-dimethyltryptamine. Tryptamine transmethylation is regulated by two products of the reaction: SAH, and DMT were shown "ex vivo" to be among the most potent inhibitors of rabbit INMT activity. This transmethylation mechanism has been