Working mass Working mass Working mass, also referred to as reaction mass, is a mass against which a system operates in order to produce acceleration. In the case of a rocket, for example, the reaction mass is the fuel shot backwards to provide propulsion. All acceleration requires an exchange of momentum, which can be thought of as the "unit of movement". Momentum is related to mass and velocity, as given by the formula "P = mv," where "P" is the momentum, "m" the mass, and "v" the velocity. The velocity of a body is easily changeable, but in most cases the mass
N,N-Dimethyltryptamine (step 1). The resulting decarboxylated tryptophan analog is tryptamine. Tryptamine then undergoes a transmethylation (step 2): the enzyme indolethylamine-N-methyltransferase (INMT) catalyzes the transfer of a methyl group from cofactor S-adenosyl-methionine (SAM), via nucleophilic attack, to tryptamine. This reaction transforms SAM into S-adenosylhomocysteine (SAH), and gives the intermediate product "N"-methyltryptamine (NMT). NMT is in turn transmethylated by the same process (step 3) to form the end product "N","N"-dimethyltryptamine. Tryptamine transmethylation is regulated by two products of the reaction: SAH, and DMT were shown "ex vivo" to be among the most potent inhibitors of rabbit INMT activity. This transmethylation mechanism has been