Glycyrrhizin Glycyrrhizin Glycyrrhizin (or glycyrrhizic acid or glycyrrhizinic acid) is the chief sweet-tasting constituent of "Glycyrrhiza glabra" (liquorice) root. Structurally, it is a saponin used as an emulsifier and gel-forming agent in foodstuffs and cosmetics. Its aglycone is enoxolone assessed as a prodrug used in Japan to reduce the risk of liver cancer in people with chronic hepatitis C. The most widely reported side effect of glycyrrhizin use via consumption of black licorice is reduction of blood potassium levels, which can affect body fluid balance and function of nerves. Chronic consumption of black licorice, even in moderate amounts, is associated with
Pontefract of two distinct and separate localities known as Tanshelf and Kirkby. The 11th-century historian, Orderic Vitalis, recorded that, in 1069, William the Conqueror travelled across Yorkshire to put down an uprising which had sacked York, but that, upon his journey to the city, he discovered that the crossing of the River Aire at what is modern-day Pontefract had been blockaded by a group of local Anglo-Scandinavian insurgents, who had broken the bridge and held the opposite bank in force. Such a crossing point would have been important in the town's early days, providing access between Pontefract and other settlements to