Glycyrrhizin an increase in blood pressure, may cause irregular heart rhythm, and adverse interactions with prescription medicines. The effects on body fluids are related to the inhibition of cortisol metabolism within the kidney, subsequent stimulation of the mineralocorticoid receptors, and decrease in blood levels of renin, potassium, and aldosterone, which collectively lead to increases in blood pressure. Depending on amount and frequency of ingesting black licorice, other side effects may include: Glycyrrhizin is under laboratory and preliminary clinical research for its possible activity against common viruses, such as hepatitis C. In vitro, glycyrrhizin inhibits the enzyme 11β-hydroxysteroid dehydrogenase. After oral ingestion,
Plant sources of anti-cancer agents podophyllotoxin which is found in "Podophyllum peltatum" (May Apple). Chemicals extracted from clippings of "Taxus brevifolia" (Pacific yew) have been used as the basis for two chemotherapy drugs, docetaxel and paclitaxel. Contains ingenol mebutate (Picato) which is used to treat skin cancer Trastuzumab emtansine (Kadcyla) is an antibody conjugated to a synthetic derivative of the cytotoxic principle of the Ethiopian plant "Maytenus ovatus". It used to treat breast cancer. Plant sources of anti-cancer agents Plant sources of anti-cancer agents are plants, the derivatives of which have been shown to be usable for the treatment or prevention of cancer in humans.