Escapement Chinese escapement spread west and was the source for Western escapement technology. According to Ahmad Y. Hassan, a mercury escapement in a Spanish work for Alfonso X in 1277 can be traced back to earlier Arabic sources. Knowledge of these mercury escapements may have spread through Europe with translations of Arabic and Spanish texts. However, none of these were true mechanical escapements, since they still depended on the flow of liquid through an orifice to measure time. For example, in Su Song's clock, water flowed into a container on a pivot. The escapement's role was to tip the container over
Controlled internal drug release Controlled internal drug release Controlled internal drug release (CIDR) devices are used in livestock for the synchronization of estrus. They are T-shaped devices with a silicone-coated nylon core. The silicone coating is impregnated with progesterone. CIDRs are inserted intra-vaginally using a specialized applicator. The flexible wings collapse for facilitated insertion and expand once placed appropriately within the vagina. The expansion of the wings retains its position; CIDRs have very high retention rates that may exceed 97%. A thin nylon tail remains exteriorized and is used for removal. Once inserted, CIDRs provide slow-release administration of progesterone, which artificially extends the luteal