Grasshopper escapement it in his prototype marine chronometers, H1 - H3, and Justin and Benjamin Vulliamy made a small number of regulators using Harrison's design, but generally it remains today what it was in Harrison's time: a brilliant, unique curiosity. A unique public clock built as a tribute to John Harrison's grasshopper escapement, the Corpus Clock, was unveiled at Corpus Christi College, Cambridge University, in Cambridge, England on 19 September 2008. Industrialist John Taylor spent £1 million building the mechanical clock. Feeling that Harrison's escapement was not well enough known, the clock's grasshopper escapement is exposed on the top of the clock,
Osmotic-controlled release oral delivery system Osmotic-controlled release oral delivery system The osmotic-controlled release oral delivery system (OROS) is an advanced controlled release oral drug delivery system in the form of a rigid tablet with a semi-permeable outer membrane and one or more small laser drilled holes in it. As the tablet passes through the body, water is absorbed through the semipermeable membrane via osmosis, and the resulting osmotic pressure is used to push the active drug through the opening(s) in the tablet. OROS is a trademarked name owned by ALZA Corporation, which pioneered the use of osmotic pumps for oral drug delivery. Osmotic release systems