Isotope-ratio mass spectrometry isotopic make up of the sample is obtained. For example, carbon isotope ratios are measured relative to the international standard for C. The C standard is produced from a fossil belemnite found in the Peedee Formation, which is a limestone formed in the Cretaceous period in South Carolina, U.S.A. The fossil is referred to as VPDB (Vienna Pee Dee Belemnite) and has C:C ratio of 0.0112372. Oxygen isotope ratios are measured relative the standard, V-SMOW (Vienna Standard Mean Ocean Water). It is critical that the sample be processed before entering the mass spectrometer so that only a single chemical species
Mononuclidic element Mononuclidic element A mononuclidic element or monotopic element is one of the 22 chemical elements that is found naturally on Earth essentially as a single nuclide (which may, or may not, be a stable nuclide). This single nuclide will have a characteristic atomic mass. Thus, the element's natural isotopic abundance is dominated either by one stable isotope or by one very long-lived isotope. There are 19 elements in the first category (which are both monoisotopic and mononuclidic), and 3 (bismuth, thorium and protactinium) in the second category (mononuclidic but not monoisotopic, since they have zero, not one, stable nuclides). A