Verge escapement St. Albans, was not a verge, but a variation called a 'strob' escapement. It consisted of a pair of escape wheels on the same axle, with alternating radial teeth. The verge rod was suspended between them, with a short crosspiece that rotated first in one direction and then the other as the staggered teeth pushed past. Although no other example is known, it is possible that this design preceded the more usual verge in clocks. For the first two hundred years or so of the mechanical clock's existence, the verge, with foliot or balance wheel, was the only escapement used
Osmotic-controlled release oral delivery system Osmotic-controlled release oral delivery system The osmotic-controlled release oral delivery system (OROS) is an advanced controlled release oral drug delivery system in the form of a rigid tablet with a semi-permeable outer membrane and one or more small laser drilled holes in it. As the tablet passes through the body, water is absorbed through the semipermeable membrane via osmosis, and the resulting osmotic pressure is used to push the active drug through the opening(s) in the tablet. OROS is a trademarked name owned by ALZA Corporation, which pioneered the use of osmotic pumps for oral drug delivery. Osmotic release systems