Polypodium glycyrrhiza very often associated with Acer macrophyllum. The fern is mycorrhizal, meaning it can form root associations with the hyphae of fungi. The sweet flavor of the rhizome was once attributed to the glycoside glycyrrhizin. However, a study has shown that the flavor may actually be due to polypodoside, which is 600 times sweeter than 6% sucrose solution. Licorice fern is cultivated as an ornamental garden plant. The cultivar 'Longicaudatum' has gained the Royal Horticultural Society's Award of Garden Merit. The licorice fern is sometimes valued for its licorice-flavored rhizome. Occasionally it is chewed, and it can also be brewed into
International Union for the Protection of New Varieties of Plants is known to consider open and un-restricted access to the genetic resources of protected plant varieties to be important to the continued development of new varieties. This opinion is indicated in the "breeders' exemption" clause of the Convention, as described above, and was reinforced in October 2005 in a reply to a notification from the Convention on Biological Diversity. In April 2003, the Convention on Biological Diversity asked the UPOV for comment on the use of Genetic Use Restriction Technologies (also known pejoratively as 'terminator genes') as they relate to the promotion of intellectual property rights. In the summary of