Immune tolerance the resulting effect is similar. Immune tolerance is important for normal physiology. Central tolerance is the main way the immune system learns to discriminate self from non-self. Peripheral tolerance is key to preventing over-reactivity of the immune system to various environmental entities (allergens, gut microbes, etc.). Deficits in central or peripheral tolerance also cause autoimmune disease, resulting in syndromes such as systemic lupus erythematosus, rheumatoid arthritis, type 1 diabetes, autoimmune polyendocrine syndrome type 1 (APS-1), and immunodysregulation polyendocrinopathy enteropathy X-linked syndrome (IPEX), and potentially contribute to asthma, allergy, and inflammatory bowel disease. And immune tolerance in pregnancy is what allows
Fetal tissue implant Fetal tissue implant Fetal tissue implant or fetal cell therapy is an experimental medical therapy where researchers implant tissue from a fetus into a person as treatment of a disease. In the case of Parkinson's disease, it is hoped that the fetal tissue would produce chemicals, specifically dopamine, which is lacking in the diseased brain. This therapy is also being investigated for treatment of Alzheimer's disease and Huntington's disease. Fetal tissue is unique since it is fast growing and has a lower possibility of rejection from the host's immune system than adult cells. In 1982, seven people in Santa Clara