Edema Edema Edema, also spelled oedema or œdema, is an abnormal accumulation of fluid in the interstitium, located beneath the skin and in the cavities of the body, which can cause severe pain. Clinically, edema manifests as swelling. The amount of interstitial fluid is determined by the balance of fluid homeostasis and the increased secretion of fluid into the interstitium. The word is from Greek "oídēma" meaning "swelling". The condition is also known (mostly archaic) as dropsy. Cutaneous edema is referred to as "pitting" when, after pressure is applied to a small area, the indentation persists after the release of the
Facial tissue Facial tissue Facial tissue, paper handkerchief, and Kleenex refers to a class of soft, absorbent, disposable papers that are suitable for use on the face. They are disposable alternatives for cloth handkerchiefs. The terms are commonly used to refer to the type of paper tissue, usually sold in boxes, that is designed to facilitate the expulsion of nasal mucus from the nose (nose-blowing) although it may refer to other types of facial tissues including napkins and wipes. Facial tissue is often referred to as a "tissue", or (in the United States) by the generic trademark "Kleenex" which popularized the invention