Immune tolerance the resulting effect is similar. Immune tolerance is important for normal physiology. Central tolerance is the main way the immune system learns to discriminate self from non-self. Peripheral tolerance is key to preventing over-reactivity of the immune system to various environmental entities (allergens, gut microbes, etc.). Deficits in central or peripheral tolerance also cause autoimmune disease, resulting in syndromes such as systemic lupus erythematosus, rheumatoid arthritis, type 1 diabetes, autoimmune polyendocrine syndrome type 1 (APS-1), and immunodysregulation polyendocrinopathy enteropathy X-linked syndrome (IPEX), and potentially contribute to asthma, allergy, and inflammatory bowel disease. And immune tolerance in pregnancy is what allows
Attack of the Wolf King Attack of the Wolf King Attack of the Wolf King is the fifth studio album from Haste the Day. The album was released on June 29, 2010 through Solid State Records. A song from the album, entitled "Travesty" was released on the band's MySpace on May 4. Lyrics for "Travesty" were released on May 21, 2010 on the band's Facebook. The song "Dog Like Vultures" has been played live since early April and debuted April 8 in Evansville, IN. This is the first album to feature new members, Dave Krysl, Giuseppe Capolupo, and Scotty Whelan. On the CD's release day,