Verge escapement be mechanical, depending on which manuscript evidence they regard as conclusive. One candidate is the Dunstable Priory clock in Bedfordshire, England built in 1283, because accounts say it was installed above the rood screen, where it would be difficult to replenish the water needed for a water clock. Another is the clock built at the Palace of the Visconti, Milan, Italy, in 1335. However, there is agreement that mechanical clocks existed by the late 13th century. The earliest description of an escapement, in Richard of Wallingford's 1327 manuscript "Tractatus Horologii Astronomici" on the clock he built at the Abbey of
Controlled internal drug release by AHI Plastic Moulding Company in Hamilton, New Zealand, in conjunction with the Ministry of Agriculture and Forestry (New Zealand). Developmental trials began in 1981. The CIDR-S was licensed in 1986 and the CIDR-G in 1988. Controlled internal drug release Controlled internal drug release (CIDR) devices are used in livestock for the synchronization of estrus. They are T-shaped devices with a silicone-coated nylon core. The silicone coating is impregnated with progesterone. CIDRs are inserted intra-vaginally using a specialized applicator. The flexible wings collapse for facilitated insertion and expand once placed appropriately within the vagina. The expansion of the wings retains