Glycyrrhizin an increase in blood pressure, may cause irregular heart rhythm, and adverse interactions with prescription medicines. The effects on body fluids are related to the inhibition of cortisol metabolism within the kidney, subsequent stimulation of the mineralocorticoid receptors, and decrease in blood levels of renin, potassium, and aldosterone, which collectively lead to increases in blood pressure. Depending on amount and frequency of ingesting black licorice, other side effects may include: Glycyrrhizin is under laboratory and preliminary clinical research for its possible activity against common viruses, such as hepatitis C. In vitro, glycyrrhizin inhibits the enzyme 11β-hydroxysteroid dehydrogenase. After oral ingestion,
Ella Pontefract Ella Pontefract Ella Pontefract (1896–1945) was the author of six books on the social history of the Yorkshire Dales related to disappearing rural traditions. Though thin and slightly built she was spirited and lively minded. Her character was charming and modest. "She loved people and was the best listener I have ever met" Joan Ingilby. The recording of reminiscences, oral history, is a very noticeable feature of the work of Ella Pontefract. Women were among the first to interrogate local inhabitants for history based on personal reminiscences. Ella and her partner Marie Hartley developed a rigorous transcription method for recording