Glycyrrhizin an increase in blood pressure, may cause irregular heart rhythm, and adverse interactions with prescription medicines. The effects on body fluids are related to the inhibition of cortisol metabolism within the kidney, subsequent stimulation of the mineralocorticoid receptors, and decrease in blood levels of renin, potassium, and aldosterone, which collectively lead to increases in blood pressure. Depending on amount and frequency of ingesting black licorice, other side effects may include: Glycyrrhizin is under laboratory and preliminary clinical research for its possible activity against common viruses, such as hepatitis C. In vitro, glycyrrhizin inhibits the enzyme 11β-hydroxysteroid dehydrogenase. After oral ingestion,
Sources for the historicity of Jesus that Tacitus wrote about Chrestians not Christians. Scholars have also debated the issue of hearsay in the reference by Tacitus. Charles Guignebert argued that "So long as there is that possibility [that Tacitus is merely echoing what Christians themselves were saying], the passage remains quite worthless". R. T. France states that the Tacitus passage is at best just Tacitus repeating what he had heard through Christians. However, Paul R. Eddy has stated that as Rome's preeminent historian, Tacitus was generally known for checking his sources and was not in the habit of reporting gossip. Tacitus was a member of the