Clock and horologes in church records, and this probably indicates that a new type of clock mechanism had been devised. Existing clock mechanisms that used water power were being adapted to take their driving power from falling weights. This power was controlled by some form of oscillating mechanism, probably derived from existing bell-ringing or alarm devices. This controlled release of power—the escapement—marks the beginning of the true mechanical clock, which differed from the previously mentioned cogwheel clocks. Verge escapement mechanism derived in the surge of true mechanical clocks, which didn't need any kind of fluid power, like water or mercury, to
Osmotic-controlled release oral delivery system separate drug layers with different concentrations of methylphenidate in addition to the (now quite robust) push layer. OROS medications include: Osmotic-controlled release oral delivery system The osmotic-controlled release oral delivery system (OROS) is an advanced controlled release oral drug delivery system in the form of a rigid tablet with a semi-permeable outer membrane and one or more small laser drilled holes in it. As the tablet passes through the body, water is absorbed through the semipermeable membrane via osmosis, and the resulting osmotic pressure is used to push the active drug through the opening(s) in the tablet. OROS is a