Molecular mass Molecular mass Relative molecular mass or molecular weight is the mass of a molecule. It is calculated as the sum of the relative atomic masses of each constituent element multiplied by the number of atoms of that element in the molecular formula. The molecular mass of small to medium size molecules, measured by mass spectrometry, determines stoichiometry. For large molecules such as proteins, methods based on viscosity and light-scattering can be used to determine molecular mass when crystallographic data are not available. Both atomic and molecular masses are usually obtained relative to the mass of the isotope C (carbon 12),
Atomic mass more significant figures than atomic weights. Standard atomic weight is related to atomic mass by the abundance ranking of isotopes for each element. It is usually "about" the same value as the atomic mass of the most abundant isotope, other than what looks like (but is not actually) a rounding difference. The atomic mass of atoms, ions, or atomic nuclei is slightly less than the sum of the masses of their constituent protons, neutrons, and electrons, due to binding energy mass loss (as per "E"="mc"). Relative "isotopic" mass (a property of a single atom) is not to be confused with