Pontefract cake map of the 1648 Siege of Pontefract (reproduced in Chartres) the liquorice is indicated as being grown in "garths" either side of Micklegate, the street which runs between Pontefract's Market Place and the castle. In the 18th century liquorice was used as a medicine both for humans and for horses. The Pontefract cake "was almost certainly a black cake, the portable lozenge used to make 'liquorish water', stamped with the castle lodge emblem of Pontefract to signify quality. This trade mark had been employed on Pontefract cakes since 1612, when the initials 'GS' were used, and are thought to be
Plant sources of anti-cancer agents podophyllotoxin which is found in "Podophyllum peltatum" (May Apple). Chemicals extracted from clippings of "Taxus brevifolia" (Pacific yew) have been used as the basis for two chemotherapy drugs, docetaxel and paclitaxel. Contains ingenol mebutate (Picato) which is used to treat skin cancer Trastuzumab emtansine (Kadcyla) is an antibody conjugated to a synthetic derivative of the cytotoxic principle of the Ethiopian plant "Maytenus ovatus". It used to treat breast cancer. Plant sources of anti-cancer agents Plant sources of anti-cancer agents are plants, the derivatives of which have been shown to be usable for the treatment or prevention of cancer in humans.