Isotope …, "m" are the atomic masses of each individual isotope, and "x", …, "x" are the relative abundances of these isotopes. Several applications exist that capitalize on properties of the various isotopes of a given element. Isotope separation is a significant technological challenge, particularly with heavy elements such as uranium or plutonium. Lighter elements such as lithium, carbon, nitrogen, and oxygen are commonly separated by gas diffusion of their compounds such as CO and NO. The separation of hydrogen and deuterium is unusual because it is based on chemical rather than physical properties, for example in the Girdler sulfide process.
Atomic mass or standard atomic weight, by several mass units. Atomic masses expressed in unified atomic mass units (i.e. relative isotopic masses) are always close to whole-number values, but never (except in the case of carbon-12) exactly a whole number, for two reasons: The ratio of atomic mass to mass number (number of nucleons) varies from about 0.99884 for Fe to 1.00782505 for H. Any mass defect due to nuclear binding energy is experimentally a small fraction (less than 1%) of the mass of equal number of free nucleons. When compared to the average mass per nucleon in carbon-12, which is moderately