Peripheral edema Peripheral edema Peripheral edema is edema (accumulation of fluid causing swelling) in tissues perfused by the peripheral vascular system, usually in the lower limbs. In the most dependent parts of the body (those hanging distally), it may be called dependent edema. The condition is commonly associated with aging, but can be caused by many other conditions, including congestive heart failure, renal failure, liver cirrhosis, portal hypertention, trauma, alcoholism, altitude sickness, pregnancy, hypertension, sickle cell anemia, compromised lymphatic system, or merely long periods of time sitting or standing without moving. Some medicines (e.g. amlodipine, pregabalin) may also cause or worsen the
Soft-tissue sarcoma muscles. If in the abdomen it can cause abdominal pains commonly mistaken for menstrual cramps, indigestion, or cause constipation. Most soft-tissue sarcomas are not associated with any known risk factors or identifiable cause. There are some exceptions: The only reliable way to determine whether a soft-tissue tumour is benign or malignant is through a biopsy. The two methods for acquisition of tumour tissue for cytopathological analysis are: A pathologist examines the tissue under a microscope. If cancer is present, the pathologist can usually determine the type of cancer and its grade. Here, 'grade' refers to a scale used to represent