Anchor escapement clocks. During the 19th century the deadbeat form gradually took over in most quality clocks, but the anchor form is still used in a few pendulum clocks today. The anchor escapement is reliable and tolerant of large geometrical errors in its construction, but its operation is similar to the old verge escapement, and retains two of the major disadvantages of the verge: The above two disadvantages were removed with the invention of an improved version of the anchor escapement: the deadbeat or Graham escapement. This is often erroneously credited to English clockmaker George Graham who introduced it around 1715 in
Controlled internal drug release Controlled internal drug release Controlled internal drug release (CIDR) devices are used in livestock for the synchronization of estrus. They are T-shaped devices with a silicone-coated nylon core. The silicone coating is impregnated with progesterone. CIDRs are inserted intra-vaginally using a specialized applicator. The flexible wings collapse for facilitated insertion and expand once placed appropriately within the vagina. The expansion of the wings retains its position; CIDRs have very high retention rates that may exceed 97%. A thin nylon tail remains exteriorized and is used for removal. Once inserted, CIDRs provide slow-release administration of progesterone, which artificially extends the luteal