Anchor escapement clockmaker George Graham around 1715. This gradually superseded the recoil escapement and is used in virtually all modern pendulum clocks with anchor escapements. The anchor escapement consists of two parts: the "escape wheel", which is a vertical wheel with pointed teeth on it rather like saw teeth, and the "anchor", shaped vaguely like a ship's anchor, which swings back and forth on a pivot just above the escape wheel. On the two arms of the anchor are curved and flat faces which the teeth of the escape wheel push against, called "pallets". The central shaft of the anchor is attached
Osmotic-controlled release oral delivery system Osmotic-controlled release oral delivery system The osmotic-controlled release oral delivery system (OROS) is an advanced controlled release oral drug delivery system in the form of a rigid tablet with a semi-permeable outer membrane and one or more small laser drilled holes in it. As the tablet passes through the body, water is absorbed through the semipermeable membrane via osmosis, and the resulting osmotic pressure is used to push the active drug through the opening(s) in the tablet. OROS is a trademarked name owned by ALZA Corporation, which pioneered the use of osmotic pumps for oral drug delivery. Osmotic release systems