Macular edema Macular edema Macular edema occurs when fluid and protein deposits collect on or under the macula of the eye (a yellow central area of the retina) and causes it to thicken and swell (edema). The swelling may distort a person's central vision, because the macula holds tightly packed cones that provide sharp, clear, central vision to enable a person to see detail, form, and color that is directly in the centre of the field of view. The causes of macular edema are numerous and different causes may be inter-related. Cystoid macular edema (CME) involves fluid accumulation in the outer plexiform
Epidemic dropsy to heart failure, pneumonia, respiratory distress syndrome or renal failure and is around 5%. Long-term follow-up studies are scanty so the long-term effects of argemone oil toxicity have not been documented. It has been reported that 25% of cases will have oedema beyond 2 months and 10% beyond 5 months. Pigmentation of skin and excessive loss of hair, which lasted 4–5 months following the disease. The majority of patients completely recover in about 3 months. ROS and Oxidative stress : Studies in the blood of dropsy patients has revealed that there is extensive ROS production (singlet oxygen and hydrogen peroxide)