Grasshopper escapement to Harrison were poor, messy and short-lived. This meant that conventional clocks had to be stopped frequently for cleaning and oiling. Using his clean and absolutely stable grasshopper escapement Harrison began a series of long-term investigations into the performance of clocks, leading to his invention of the gridiron pendulum which counteracted the effects of expansion and contraction with changing temperature. The performance of his improved clocks in turn gave him an accurate, convenient standard against which to test his marine timekeepers. Harrison developed the grasshopper escapement from a conventional anchor escapement which he built for a turret clock to go
Osmotic-controlled release oral delivery system separate drug layers with different concentrations of methylphenidate in addition to the (now quite robust) push layer. OROS medications include: Osmotic-controlled release oral delivery system The osmotic-controlled release oral delivery system (OROS) is an advanced controlled release oral drug delivery system in the form of a rigid tablet with a semi-permeable outer membrane and one or more small laser drilled holes in it. As the tablet passes through the body, water is absorbed through the semipermeable membrane via osmosis, and the resulting osmotic pressure is used to push the active drug through the opening(s) in the tablet. OROS is a