Lithium be cut with a knife. When cut, it possesses a silvery-white color that quickly changes to gray as it oxidizes to lithium oxide. While it has one of the lowest melting points among all metals (180 °C), it has the highest melting and boiling points of the alkali metals. Lithium has a very low density (0.534 g/cm), comparable with pine wood. It is the least dense of all elements that are solids at room temperature; the next lightest solid element (potassium, at 0.862 g/cm) is more than 60% denser. Furthermore, apart from helium and hydrogen, it is less dense than
Dose-dense chemotherapy allow rapid growth for a short time before the next treatment. By decreasing the dose and increasing the frequency, the fast growth can be prevented, allowing for faster and more effective cure rate. Although the dose is reduced in each treatment, the total quantity of chemotherapy may or may not be increased over the duration of the typical treatment time. For example, in standard treatment of ovarian cancer, paclitaxel is given at 175 mg/m body surface every three weeks. In dose dense therapy paclitaxel is given at 50–80 mg/m every week (150–240 mg/m in 3-weeks). Dose-dense chemotherapy Dose-dense chemotherapy is