Polypodium glycyrrhiza very often associated with Acer macrophyllum. The fern is mycorrhizal, meaning it can form root associations with the hyphae of fungi. The sweet flavor of the rhizome was once attributed to the glycoside glycyrrhizin. However, a study has shown that the flavor may actually be due to polypodoside, which is 600 times sweeter than 6% sucrose solution. Licorice fern is cultivated as an ornamental garden plant. The cultivar 'Longicaudatum' has gained the Royal Horticultural Society's Award of Garden Merit. The licorice fern is sometimes valued for its licorice-flavored rhizome. Occasionally it is chewed, and it can also be brewed into
Plant sources of anti-cancer agents podophyllotoxin which is found in "Podophyllum peltatum" (May Apple). Chemicals extracted from clippings of "Taxus brevifolia" (Pacific yew) have been used as the basis for two chemotherapy drugs, docetaxel and paclitaxel. Contains ingenol mebutate (Picato) which is used to treat skin cancer Trastuzumab emtansine (Kadcyla) is an antibody conjugated to a synthetic derivative of the cytotoxic principle of the Ethiopian plant "Maytenus ovatus". It used to treat breast cancer. Plant sources of anti-cancer agents Plant sources of anti-cancer agents are plants, the derivatives of which have been shown to be usable for the treatment or prevention of cancer in humans.