Glycyrrhizin an increase in blood pressure, may cause irregular heart rhythm, and adverse interactions with prescription medicines. The effects on body fluids are related to the inhibition of cortisol metabolism within the kidney, subsequent stimulation of the mineralocorticoid receptors, and decrease in blood levels of renin, potassium, and aldosterone, which collectively lead to increases in blood pressure. Depending on amount and frequency of ingesting black licorice, other side effects may include: Glycyrrhizin is under laboratory and preliminary clinical research for its possible activity against common viruses, such as hepatitis C. In vitro, glycyrrhizin inhibits the enzyme 11β-hydroxysteroid dehydrogenase. After oral ingestion,
West Yorkshire Urban Area West Yorkshire Urban Area The West Yorkshire Built-up Area, previously known as the West Yorkshire Urban Area is a term used by the Office for National Statistics (ONS) to refer to a conurbation in West Yorkshire, England, based on the cities of Leeds, Bradford and Wakefield, and the large towns of Huddersfield and Halifax. It is the 4th largest urban area in the United Kingdom. However, it excludes towns such as Castleford, Pontefract and Wetherby which though part of the county of West Yorkshire are considered independently. There are substantial areas of agricultural land within the designated area - more