Myosin as a person with longer legs can move farther with each individual step. The velocity of a myosin motor depends upon the rate at which it passes through a complete kinetic cycle of ATP binding to the release of ADP. Myosin I, a ubiquitous cellular protein, functions as monomer and functions in vesicle transport. It has step size of 10 nm and has been implicated as being responsible for the adaptation response of the stereocilia in the inner ear. Myosin II (also known as conventional myosin) is the myosin type responsible for producing muscle contraction in muscle cells. In muscle
Extracellular matrix exist in varying degrees of stiffness and elasticity, from soft brain tissues to hard bone tissues. The elasticity of the ECM can differ by several orders of magnitude. This property is primarily dependent on collagen and elastin concentration, and it has recently been shown to play an influential role in regulating numerous cell functions. Cells can sense the mechanical properties of their environment by applying forces and measuring the resulting backlash. This plays an important role because it helps regulate many important cellular processes including cellular contraction, cell migration, cell proliferation, differentiation and cell death (apoptosis). Inhibition of nonmuscle myosin