Glycyrrhizin Glycyrrhizin Glycyrrhizin (or glycyrrhizic acid or glycyrrhizinic acid) is the chief sweet-tasting constituent of "Glycyrrhiza glabra" (liquorice) root. Structurally, it is a saponin used as an emulsifier and gel-forming agent in foodstuffs and cosmetics. Its aglycone is enoxolone assessed as a prodrug used in Japan to reduce the risk of liver cancer in people with chronic hepatitis C. The most widely reported side effect of glycyrrhizin use via consumption of black licorice is reduction of blood potassium levels, which can affect body fluid balance and function of nerves. Chronic consumption of black licorice, even in moderate amounts, is associated with
Pontefract of Pontefract was known by the Anglo-Scandinavian name of Kirkby. After the Norman conquest in 1066 almost all of Yorkshire came under the ownership of followers of William the Conqueror, one of whom was Ilbert de Lacy who became the owner of Tateshale (Tanshelf) where he began to build a castle. Pontefract Castle began as a wooden motte and bailey castle, built before 1086 and later rebuilt in stone. The de Lacys lived in the castle for more than two centuries and were holders of the castle and the Honour of Pontefract from 1067 until the death of Alice de