Public Health Emergency of International Concern second PHEIC was issued in May 2014 with the resurgence of polio after its near-eradication, deemed "an extraordinary event." On Friday, August 8, 2014, the World Health Organization declared its third Public Health Emergency of International Concern in response to the outbreak of Ebola in Western Africa. On Monday, February 1, 2016, the World Health Organization declared its fourth PHEIC in response to clusters of microcephaly and Guillain–Barré syndrome in the Americas, which at the time were suspected to be associated with the ongoing outbreak of Zika virus. Later research and evidence bore out these concerns; in April, the WHO
Foreign animal disease FAO Food Chain Crisis Management Framework, grouping the three thematic EMPRES, provides an effective, multidisciplinary and coherent approach to threats affecting the food chain by integrating prevention, early warning, preparedness and response. The Crisis Management Centre-Animal Health (CMC-AH) is FAO's rapid response unit to animal disease emergencies. The CMC-AH is a joint division of FAO's Animal Production and Health and Emergency and Rehabilitation Divisions, and established in partnership with the World Organization for Animal Health (OIE). The CMC-AH sends rapid response missions to countries to help assess epidemiological situations, diagnose outbreaks of animal diseases, and set up immediate measure to