Period 2 element two make up all natural occurrence of lithium on Earth, although further isotopes have been synthesized. In ionic compounds, lithium loses an electron to become positively charged, forming the cation Li. Lithium is the first alkali metal in the periodic table, and the first metal of any kind in the periodic table. At standard temperature and pressure, lithium is a soft, silver-white, highly reactive metal. With a density of 0.564 g·cm, lithium is the lightest metal and the least dense solid element. Lithium is one of the few elements synthesized in the Big Bang, making it a primordial element. Lithium
Dose-dense chemotherapy Dose-dense chemotherapy Dose-dense chemotherapy is a chemotherapy treatment plan in which drugs are given with less time between treatments than in a standard chemotherapy treatment plan. The Gompertzian model of tumor cell growth shows tumor cells growing fastest when the tumor is small. When a large (slow growing) tumor is surgically removed, microtumors or individual neoplastic cells that remain will be able to grow at their fastest rate. Standard treatment may include chemotherapy once every three weeks. This would allow bone marrow and gastrointestinal tract recovery before the next treatment and would inhibit the tumor for a short time, but