Isotope fractionation Isotope fractionation Isotope fractionation describes processes that affect the relative abundance of isotopes, often used in isotope geochemistry. Normally, the focus is on stable isotopes of the same element. Isotopic fractionation in the natural environment can be measured by isotope analysis, using isotope-ratio mass spectrometry, to separate different element isotopes on the basis of their mass-to-charge ratio, an important tool to understand natural systems. For example, in biochemistry processes cause a fluctuation in the amount of isotopes of carbon ratios incorporated into a biological being. The difference between the true amount of carbon and the amount in the plant is
Isotope neutron number to atomic number varies the most between isotopes it usually has only a small effect, although it does matter in some circumstances (for hydrogen, the lightest element, the isotope effect is large enough to strongly affect biology). The term "isotopes" (originally also "isotopic elements", now sometimes "isotopic nuclides") is intended to imply comparison (like "synonyms" or "isomers"), for example: the nuclides , , are isotopes (nuclides with the same atomic number but different mass numbers), but , , are isobars (nuclides with the same mass number). However, because "isotope" is the older term, it is better known than