Glycyrrhizin an increase in blood pressure, may cause irregular heart rhythm, and adverse interactions with prescription medicines. The effects on body fluids are related to the inhibition of cortisol metabolism within the kidney, subsequent stimulation of the mineralocorticoid receptors, and decrease in blood levels of renin, potassium, and aldosterone, which collectively lead to increases in blood pressure. Depending on amount and frequency of ingesting black licorice, other side effects may include: Glycyrrhizin is under laboratory and preliminary clinical research for its possible activity against common viruses, such as hepatitis C. In vitro, glycyrrhizin inhibits the enzyme 11β-hydroxysteroid dehydrogenase. After oral ingestion,
Pontefract at Moor Lane Carleton. It runs three senior sides as well as a number of junior and girls teams. Rugby Union has been played in the town since the 19th Century when Pontefract won the Yorkshire Cup. Pontefract Pontefract is a historic market town in West Yorkshire, England, near the A1 (or Great North Road) and the M62 motorway. Historically part of the West Riding of Yorkshire, it is one of the five towns in the metropolitan borough of the City of Wakefield and has a population of 28,250, increasing to 30,881 at the 2011 Census. Pontefract's motto is "Post