Glycyrrhizin an increase in blood pressure, may cause irregular heart rhythm, and adverse interactions with prescription medicines. The effects on body fluids are related to the inhibition of cortisol metabolism within the kidney, subsequent stimulation of the mineralocorticoid receptors, and decrease in blood levels of renin, potassium, and aldosterone, which collectively lead to increases in blood pressure. Depending on amount and frequency of ingesting black licorice, other side effects may include: Glycyrrhizin is under laboratory and preliminary clinical research for its possible activity against common viruses, such as hepatitis C. In vitro, glycyrrhizin inhibits the enzyme 11β-hydroxysteroid dehydrogenase. After oral ingestion,
Varieties of Chinese the second family. The ordinary negators in these varieties are all derived from a syllabic nasal *m̩, though it has a level tone in Hakka and Yue and a rising tone in Min. Existential negators derive from a proto-form *mau, though again the tonal category varies between groups. First- and second-person pronouns are cognate across all varieties. For third-person pronouns, Jin, Mandarin, and Xiang varieties have cognate forms, but other varieties generally use forms that originally had a velar or glottal initial: Southern varieties also include distinctive substrata of vocabulary of non-Chinese origin. Some of these words may have come