Glycyrrhizin an increase in blood pressure, may cause irregular heart rhythm, and adverse interactions with prescription medicines. The effects on body fluids are related to the inhibition of cortisol metabolism within the kidney, subsequent stimulation of the mineralocorticoid receptors, and decrease in blood levels of renin, potassium, and aldosterone, which collectively lead to increases in blood pressure. Depending on amount and frequency of ingesting black licorice, other side effects may include: Glycyrrhizin is under laboratory and preliminary clinical research for its possible activity against common viruses, such as hepatitis C. In vitro, glycyrrhizin inhibits the enzyme 11β-hydroxysteroid dehydrogenase. After oral ingestion,
Pontefract Tanshelf railway station Pontefract Tanshelf railway station Pontefract Tanshelf railway station is the most central station in the town of Pontefract, West Yorkshire, England, and serves Pontefract Races, the racecourse located just down the street from the station. It lies on the Pontefract Line operated by Northern and is east of Wakefield Kirkgate. In the days of coal mining in the Pontefract area, the station served the needs of the local workforce with regular and frequent services timed for the beginning and the end of mining shifts. The present station was opened by West Yorkshire Metro on 12 May 1992, when the line