Lever escapement and other parts out of harder materials than steel, eliminating the need for lubrication. Materials being tried include silicon, nickel phosphorus, diamond, and diamond-on-silicon. Ulysse Nardin in 2001, Patek Philippe in 2005, and Zenith (watchmaker) in 2013 introduced watches with silicon escape wheels. Lever escapement The lever escapement, invented by British clockmaker Thomas Mudge in 1755, is a type of escapement that is used in almost all mechanical watches, as well as small mechanical non-pendulum clocks, alarm clocks, and kitchen timers. An escapement is a mechanical linkage that gives pushes to the timepiece's balance wheel, keeping it rotating back and
Osmotic-controlled release oral delivery system Osmotic-controlled release oral delivery system The osmotic-controlled release oral delivery system (OROS) is an advanced controlled release oral drug delivery system in the form of a rigid tablet with a semi-permeable outer membrane and one or more small laser drilled holes in it. As the tablet passes through the body, water is absorbed through the semipermeable membrane via osmosis, and the resulting osmotic pressure is used to push the active drug through the opening(s) in the tablet. OROS is a trademarked name owned by ALZA Corporation, which pioneered the use of osmotic pumps for oral drug delivery. Osmotic release systems