Cardiovascular disease strategies. A 2015 Cochrane Review found some evidence that interventions aiming to reduce more than one cardiovascular risk factor may have beneficial effects on blood pressure, body mass index and waist circumference; however, evidence was limited and the authors were unable to draw firm conclusions on the effects on cardiovascular events and mortality. For adults without a known diagnosis of hypertension, diabetes, hyperlipidemia, or cardiovascular disease, routine counseling to advise them to improve their diet and increase their physical activity has not been found to significantly alter behavior, and thus is not recommended. Another Cochrane review suggested that simply providing
Helen Hobbs Dallas Heart Ball Chair in Cardiology Research, Philip O'Bryan Montgomery Jr., M.D., Distinguished Chair in Developmental Biology, and Eugene McDermott Distinguished Chair for the Study of Human Growth and Development. In 1999, she co-founded the Dallas Heart Study with Dr. Jonathan Cohen with a grant from the Donald W. Reynolds Foundation. This study takes genetic samples of thousands of people, representative of the population of Dallas, and correlates them to the subject's health metrics. Through this study, she found that variations in the gene PCSK9 led to increased protection from cardiovascular disease. Recent results from the genetic study show that