Isotope-ratio mass spectrometry isotopic make up of the sample is obtained. For example, carbon isotope ratios are measured relative to the international standard for C. The C standard is produced from a fossil belemnite found in the Peedee Formation, which is a limestone formed in the Cretaceous period in South Carolina, U.S.A. The fossil is referred to as VPDB (Vienna Pee Dee Belemnite) and has C:C ratio of 0.0112372. Oxygen isotope ratios are measured relative the standard, V-SMOW (Vienna Standard Mean Ocean Water). It is critical that the sample be processed before entering the mass spectrometer so that only a single chemical species
Relative atomic mass which is then compared to the atomic mass of carbon-12. This comparison is the quotient of the two weights, which makes the value dimensionless (no unit appended). This quotient also explains the word "relative": the sample mass value is considered relative to that of carbon-12.. It is a synonym for atomic weight, though it is not to be confused with relative isotopic mass. Relative atomic mass is also frequently used as a synonym for "standard" atomic weight and these quantities may have overlapping values if the relative atomic mass used is that for an element from Earth under defined conditions.