Peripheral edema Peripheral edema Peripheral edema is edema (accumulation of fluid causing swelling) in tissues perfused by the peripheral vascular system, usually in the lower limbs. In the most dependent parts of the body (those hanging distally), it may be called dependent edema. The condition is commonly associated with aging, but can be caused by many other conditions, including congestive heart failure, renal failure, liver cirrhosis, portal hypertention, trauma, alcoholism, altitude sickness, pregnancy, hypertension, sickle cell anemia, compromised lymphatic system, or merely long periods of time sitting or standing without moving. Some medicines (e.g. amlodipine, pregabalin) may also cause or worsen the
Facial tissue Facial tissue Facial tissue, paper handkerchief, and Kleenex refers to a class of soft, absorbent, disposable papers that are suitable for use on the face. They are disposable alternatives for cloth handkerchiefs. The terms are commonly used to refer to the type of paper tissue, usually sold in boxes, that is designed to facilitate the expulsion of nasal mucus from the nose (nose-blowing) although it may refer to other types of facial tissues including napkins and wipes. Facial tissue is often referred to as a "tissue", or (in the United States) by the generic trademark "Kleenex" which popularized the invention