Glycyrrhizin an increase in blood pressure, may cause irregular heart rhythm, and adverse interactions with prescription medicines. The effects on body fluids are related to the inhibition of cortisol metabolism within the kidney, subsequent stimulation of the mineralocorticoid receptors, and decrease in blood levels of renin, potassium, and aldosterone, which collectively lead to increases in blood pressure. Depending on amount and frequency of ingesting black licorice, other side effects may include: Glycyrrhizin is under laboratory and preliminary clinical research for its possible activity against common viruses, such as hepatitis C. In vitro, glycyrrhizin inhibits the enzyme 11β-hydroxysteroid dehydrogenase. After oral ingestion,
Wakefield and Pontefract Community Health NHS Trust Wakefield and Pontefract Community Health NHS Trust Wakefield and Pontefract Community Health NHS Trust was a Community health NHS trust which served the Wakefield metropolitan district, West Yorkshire providing community, mental health and learning disability services. The Trust was formed on 1 April 1993 and operated from a number of locations including Fieldhead Hospital, The Yorkshire Centre for Forensic Psychiatry (also known as Newton Lodge) the former Castleford, Normanton and District; Southmoor; and Ackton Hospitals (all now closed) and numerous health centres and other standalone units across the Wakefield district. The headquarters for the Trust was called Fernbank and was