Ebola virus disease in Spain had become unwell and on 6 October tested positive for Ebola at her local hospital in Alcorcón, the Hospital Universitario Fundación Alcorcón. A second test confirmed the diagnosis, making this the first confirmed case of Ebola transmission outside Africa. Following testing, she was transferred to the Hospital Carlos III in Madrid for treatment. As of October 7, 50 contacts were being monitored, with 7 kept in isolation at the Hospital Carlos III, and an investigation was under way. On 7 October, Madrid's regional government got a court order to euthanize Romero's pet dog, Excalibur, concerned that it posed a risk
2018 Kivu Ebola outbreak time to treat infected individuals during this EVD outbreak. An alternative treatment of ZMapp has not been used because it requires storage at . On 25 November, the Democratic Republic of the Congo gave approval to start clinical trials for Ebola (EVD) treatment. Medical authorities will not choose which of the four experimental treatments will be given to an individual; instead it will be randomized. On 8 August, the process of vaccination began with rVSV-ZEBOV Ebola vaccine. Although the Ebola vaccine has had efficacy, a review by Medaglini "et al." indicated that "long-term protection is undefined" via the vaccine mechanism.