Mixed connective tissue disease connective tissue disease is not necessarily associated with serum antibodies directed against the U1-RNP, and MCTD is associated with a more clearly defined set of signs/symptoms. MCTD combines features of scleroderma, myositis, systemic lupus erythematosus, and rheumatoid arthritis (with some sources adding polymyositis, dermatomyositis, and inclusion body myositis) and is thus considered an overlap syndrome. MCTD commonly causes: It has been associated with HLA-DR4. Distinguishing laboratory characteristics are a positive, speckled anti-nuclear antibody and an anti-U1-RNP antibody. The prognosis of mixed connective tissue disease is in one third of cases worse than that of systemic lupus erythematosus (SLE). In spite
Attack of the Wolf King Attack of the Wolf King Attack of the Wolf King is the fifth studio album from Haste the Day. The album was released on June 29, 2010 through Solid State Records. A song from the album, entitled "Travesty" was released on the band's MySpace on May 4. Lyrics for "Travesty" were released on May 21, 2010 on the band's Facebook. The song "Dog Like Vultures" has been played live since early April and debuted April 8 in Evansville, IN. This is the first album to feature new members, Dave Krysl, Giuseppe Capolupo, and Scotty Whelan. On the CD's release day,