Globalization and disease Spanish soldiers introduced smallpox by contact with natives of the Aztec capital Tenochtitlan. A devastating epidemic broke out among the indigenous people, killing thousands. In 1617, smallpox reached Massachusetts, probably brought by earlier explorers to Nova Scotia, Canada.” By 1638 the disease had broken out among people in Boston, Massachusetts. In 1721 people fled the city after an outbreak, but the residents spread the disease to others throughout the thirteen colonies. Smallpox broke out in six separate epidemics in the United States through 1968. The smallpox vaccine was developed in 1798 by Edward Jenner. By 1979 the disease had been
Indigenous people of the Everglades region giving eco-tours of their land. As of 2008, there were six Seminole and Miccosukee reservations throughout Florida; they feature casino gaming that supports the tribe. Indigenous people of the Everglades region The indigenous people of the Everglades region arrived in the Florida peninsula of what is now the United States approximately 14,000 to 15,000 years ago, probably following large game. The Paleo-Indians found an arid landscape that supported plants and animals adapted to prairie and xeric scrub conditions. Large animals became extinct in Florida around 11,000 years ago. Climate changes 6,500 years ago brought a wetter landscape. The Paleo-Indians slowly