Corrosive substance due to their capabilities of dissolving greases, proteins or mineral deposits such as limescale inside water pipes. In chemical uses, high chemical reactivity is often desirable, as the rates of chemical reactions depend on the activity (effective concentration) of the reactive species. For instance, catalytic sulfuric acid is used in the alkylation process in an oil refinery: the activity of carbocations, the reactive intermediate, is higher with stronger acidity, and thus the reaction proceeds faster. Once used, corrosives are most often recycled or neutralized. However, there have been environmental problems with untreated corrosive effluents or accidental discharges. Corrosive substance A
Substance P nitric oxide release. Substance P is involved in the axon reflex-mediated vasodilatation to local heating and wheal and flare reaction. It has been shown that vasodilatation to substance P is dependent on the NK1 receptor located on the endothelium. In contrast to other neuropeptides studied in human skin, substance P-induced vasodilatation has been found to decline during continuous infusion. This possibly suggests an internalization of neurokinin-1 (NK1). As is typical with many vasodilators, it also has bronchoconstrictive properties, administered through the non-adrenergic, non-cholinergic nervous system (branch of the vagal system). SP initiates expression of almost all known immunological chemical messengers