Indigenous peoples of the Americas Smallpox killed from one third to half of the native population of Hispaniola in 1518. By killing the Incan ruler Huayna Capac, smallpox caused the Inca Civil War of 1529–1532. Smallpox was only the first epidemic. Typhus (probably) in 1546, influenza and smallpox together in 1558, smallpox again in 1589, diphtheria in 1614, measles in 1618—all ravaged the remains of Inca culture. Smallpox killed millions of native inhabitants of Mexico. Unintentionally introduced at Veracruz with the arrival of Pánfilo de Narváez on April 23, 1520, smallpox ravaged Mexico in the 1520s, possibly killing over 150,000 in Tenochtitlán (the heartland of
Indigenous peoples of Mexico identity not linked to racial or ethnic identity was an aim of Mexican liberalism. In the late twentieth century there has been a push for indigenous rights and a recognition of indigenous cultural identity. According to the constitutional reform of 2001, the following rights of indigenous peoples are recognized: During the early colonial era in central Mexico, Spaniards were more interested in having access to indigenous labor than in ownership of land. The institution of the encomienda, a crown grant of the labor of particular indigenous communities to individuals was a key element of the imposition of Spanish rule, with