Population history of indigenous peoples of the Americas scope of the epidemics over the years was tremendous, killing millions of people—possibly in excess of 90% of the population in the hardest hit areas—and creating one of "the greatest human catastrophe in history, far exceeding even the disaster of the Black Death of medieval Europe", which had killed up to one-third of the people in Europe and Asia between 1347 and 1351. One of the most devastating diseases was smallpox, but other deadly diseases included typhus, measles, influenza, bubonic plague, cholera, malaria, tuberculosis, mumps, yellow fever and pertussis, which were chronic in Eurasia. This transfer of disease between the
Indigenous people of the Everglades region powerful in number and political structure. Their territory was centered on modern-day Ft. Myers, and extended as far north as Tampa, as far east as Lake Okeechobee, and as far south as the Keys. The Tequesta lived on the southeastern coast of the Florida peninsula around what is today Biscayne Bay and the Miami River. Both societies were well adapted to live in the various ecosystems of the Everglades regions. Their people often traveled through the heart of the Everglades, though they rarely lived within it. After more than 210 years of relations with the Spanish, both indigenous societies lost