Globalization and disease Spanish soldiers introduced smallpox by contact with natives of the Aztec capital Tenochtitlan. A devastating epidemic broke out among the indigenous people, killing thousands. In 1617, smallpox reached Massachusetts, probably brought by earlier explorers to Nova Scotia, Canada.” By 1638 the disease had broken out among people in Boston, Massachusetts. In 1721 people fled the city after an outbreak, but the residents spread the disease to others throughout the thirteen colonies. Smallpox broke out in six separate epidemics in the United States through 1968. The smallpox vaccine was developed in 1798 by Edward Jenner. By 1979 the disease had been
Indigenous peoples of the Americas 2009, at the same time as general elections to office. The issue divided the country. At that time, indigenous peoples voted overwhelmingly for more autonomy: five departments that had not already done so voted for it; as did Gran Chaco Province in Taríja, for regional autonomy; and 11 of 12 municipalities that had referendums on this issue. Indigenous peoples of Brazil make up 0.4% of Brazil's population, or about 817,000 people, but millions of Brazilians are mestizo or have some indigenous ancestry. Indigenous peoples are found in the entire territory of Brazil, although in the 21st century, the majority of