Globalization and disease Spanish soldiers introduced smallpox by contact with natives of the Aztec capital Tenochtitlan. A devastating epidemic broke out among the indigenous people, killing thousands. In 1617, smallpox reached Massachusetts, probably brought by earlier explorers to Nova Scotia, Canada.” By 1638 the disease had broken out among people in Boston, Massachusetts. In 1721 people fled the city after an outbreak, but the residents spread the disease to others throughout the thirteen colonies. Smallpox broke out in six separate epidemics in the United States through 1968. The smallpox vaccine was developed in 1798 by Edward Jenner. By 1979 the disease had been
Indigenous Australians island and the rest of mainland Australia during the last glacial period. Estimates of the population of the Aboriginal people of Tasmania, before European arrival, are in the range of 3,000 to 15,000 people although genetic studies have suggested significantly higher figures, which are supported by Indigenous oral traditions that indicate a reduction in population from diseases introduced by British and American sealers before settlement. The original population was further reduced to around 300 between 1803 and 1833 due to disease, warfare and other actions of British settlers. Despite over 170 years of debate over who or what was responsible