Population history of indigenous peoples of the Americas scope of the epidemics over the years was tremendous, killing millions of people—possibly in excess of 90% of the population in the hardest hit areas—and creating one of "the greatest human catastrophe in history, far exceeding even the disaster of the Black Death of medieval Europe", which had killed up to one-third of the people in Europe and Asia between 1347 and 1351. One of the most devastating diseases was smallpox, but other deadly diseases included typhus, measles, influenza, bubonic plague, cholera, malaria, tuberculosis, mumps, yellow fever and pertussis, which were chronic in Eurasia. This transfer of disease between the
Genocide of indigenous peoples considered genocide can be a matter of scholarly debate. Historians often draw on broader definitions such as Lemkin's, which sees colonialist violence against indigenous peoples as inherently genocidal. For example, in the case of the colonization of the Americas, where 90% of the indigenous people of the Americas were wiped out in 500 years of European colonization, it can be debatable whether genocide occurs when disease is considered the main cause of population decline since the introduction of disease was mostly unintentional. Some genocide scholars separate the population declines due to disease from the genocidal aggression of one group toward