Refractory period (sex) for treating sexual dysfunction. Sildenafil, used in the treatment of erectile dysfunction, was found in one scientific study to have caused "a decreased postejaculatory erectile refractory time (3.2 ± 0.7 vs. 6.4 ± 0.7 minutes)" in men diagnosed with premature ejaculation. It is additionally proposed that the gonadotropin inhibitory hormone (GnIH), which is considered to inhibit the hypothalamic-pituitary-gonadal axis and sexual functions causes refractoriness of the post-ejaculatory refractory period. This hypothesis also supports the increase of oxytocin and prolactin after orgasm in accordance with the previous studies. One alternative theory explains the male refractory period in terms of a peripheral
Refractory period (sex) al." reported a single male individual producing multiple orgasms without elevated prolactin response. A number of books assert that men are capable of eliminating the refractory period and having multiple orgasms similar to female multiple orgasms by learning to separate ejaculation from orgasm, and describe techniques they claim will help men stop ejaculation and thus eliminate the refractory period. In addition, many men who began masturbation or other sexual activity prior to puberty report the ability of having been able to achieve multiple, non-ejaculatory orgasms without refractory periods during that time in their lives. Refractory period (sex) In human sexuality,