Caduceus is a continuation of the older Indo-European dragon-slayer motif. Wilhelm Heinrich Roscher (1913) pointed out that the serpent as an attribute of both Hermes and Asclepius is a variant of the "pre-historic semi-chthonic serpent hero known at Delphi as Python", who in classical mythology is slain by Apollo. One Greek myth of origin of the caduceus is part of the story of Tiresias, who found two snakes copulating and killed the female with his staff. Tiresias was immediately turned into a woman, and so remained until he was able to repeat the act with the male snake seven years later.
Horned Serpent Horned Serpent The Horned Serpent appears in the mythologies of many Native Americans. Details vary among tribes, with many of the stories associating the mystical figure with water, rain, lightning and thunder. Horned Serpents were major components of the Southeastern Ceremonial Complex of North American prehistory. Horned serpents also appear in European and Near Eastern mythology. Horned serpents appear in the oral history of numerous Native American cultures, especially in the Southeastern Woodlands and Great Lakes. Muscogee Creek traditions include a Horned Serpent and a Tie-Snake, "estakwvnayv" in the Muscogee Creek language. These are sometimes interpreted as being the same