Refractory period (sex) after orgasm in which further sexual stimulation does not produce excitement. While the refractory period varies widely among individuals, ranging from minutes to days, most men cannot achieve or maintain an erection during this time, and many perceive a psychological feeling of satisfaction and are temporarily uninterested in further sexual activity; the penis may be hypersensitive and further sexual stimulation may feel painful during this time frame. An increased infusion of the hormone oxytocin during ejaculation is believed to be chiefly responsible for the male refractory period, and the amount by which oxytocin is increased may affect the length of
Corticotropin-releasing hormone receptor 1 II and urocortin III. Variations in the "CRHR1" gene is associated with enhanced response to inhaled corticosteroid therapy in asthma. CRF1 triggers cells to release hormones that are linked to stress and anxiety [original reference missing].Hence CRF1 receptor antagonists are being actively studied as possible treatments for depression and anxiety. Variations in CRHR1 are associated with persistent pulmonary hypertension of the newborn. Corticotropin-releasing hormone receptor 1 has been shown to interact with Corticotropin-releasing hormone and Urocortin. Corticotropin-releasing hormone receptor 1 Corticotropin-releasing hormone receptor 1 (CRHR1) is a protein, also known as CRF, with the latter (CRF) now being the IUPHAR-recommended