Indigenous peoples of the Americas Smallpox killed from one third to half of the native population of Hispaniola in 1518. By killing the Incan ruler Huayna Capac, smallpox caused the Inca Civil War of 1529–1532. Smallpox was only the first epidemic. Typhus (probably) in 1546, influenza and smallpox together in 1558, smallpox again in 1589, diphtheria in 1614, measles in 1618—all ravaged the remains of Inca culture. Smallpox killed millions of native inhabitants of Mexico. Unintentionally introduced at Veracruz with the arrival of Pánfilo de Narváez on April 23, 1520, smallpox ravaged Mexico in the 1520s, possibly killing over 150,000 in Tenochtitlán (the heartland of
Mexican settlement in the Philippines Mexican immigrants to the Philippines, they belonged to different ethnic groups such as indigenous and mestizos and Creoles who mainly mixed with the local population, which also increased the number of descendants with Spanish surnames. The construction of the military fort of Zamboanga counted with the help of these Mexican immigrants who had already settled in the islands. The Mexican legacy in the Philippines, consisting of marriage between the Spanish and the indigenous culture of origin (Maya and Nahuatl), has been marked in these islands. Many words that originated from Nahuatl, a language spoken by the descendants of the indigenous