Indigenous peoples of the Americas Smallpox killed from one third to half of the native population of Hispaniola in 1518. By killing the Incan ruler Huayna Capac, smallpox caused the Inca Civil War of 1529–1532. Smallpox was only the first epidemic. Typhus (probably) in 1546, influenza and smallpox together in 1558, smallpox again in 1589, diphtheria in 1614, measles in 1618—all ravaged the remains of Inca culture. Smallpox killed millions of native inhabitants of Mexico. Unintentionally introduced at Veracruz with the arrival of Pánfilo de Narváez on April 23, 1520, smallpox ravaged Mexico in the 1520s, possibly killing over 150,000 in Tenochtitlán (the heartland of
Indigenous peoples of the Americas 2009, at the same time as general elections to office. The issue divided the country. At that time, indigenous peoples voted overwhelmingly for more autonomy: five departments that had not already done so voted for it; as did Gran Chaco Province in Taríja, for regional autonomy; and 11 of 12 municipalities that had referendums on this issue. Indigenous peoples of Brazil make up 0.4% of Brazil's population, or about 817,000 people, but millions of Brazilians are mestizo or have some indigenous ancestry. Indigenous peoples are found in the entire territory of Brazil, although in the 21st century, the majority of