Globalization and disease Spanish soldiers introduced smallpox by contact with natives of the Aztec capital Tenochtitlan. A devastating epidemic broke out among the indigenous people, killing thousands. In 1617, smallpox reached Massachusetts, probably brought by earlier explorers to Nova Scotia, Canada.” By 1638 the disease had broken out among people in Boston, Massachusetts. In 1721 people fled the city after an outbreak, but the residents spread the disease to others throughout the thirteen colonies. Smallpox broke out in six separate epidemics in the United States through 1968. The smallpox vaccine was developed in 1798 by Edward Jenner. By 1979 the disease had been
Seediq people indigenous people defeated 670 Japanese soldiers. As a result of this, in 1902, the Japanese isolated Wushe. Between 1914 and 1917, Japanese forces carried out an aggressive 'pacification' program killing many resisting people. At this time, the leader of Mahebo, Mona Rudao, tried to resist rule by Japan, but he failed twice because his plans were divulged. At his third attempt, he organized seven out of twelve groups to fight against the Japanese forces. When Japanese soldiers raped some indigenous women, two leaders and twenty men killed thirteen Japanese soldiers. After taking over the plain, Japanese gained control of Wushe.