Globalization and disease Spanish soldiers introduced smallpox by contact with natives of the Aztec capital Tenochtitlan. A devastating epidemic broke out among the indigenous people, killing thousands. In 1617, smallpox reached Massachusetts, probably brought by earlier explorers to Nova Scotia, Canada.” By 1638 the disease had broken out among people in Boston, Massachusetts. In 1721 people fled the city after an outbreak, but the residents spread the disease to others throughout the thirteen colonies. Smallpox broke out in six separate epidemics in the United States through 1968. The smallpox vaccine was developed in 1798 by Edward Jenner. By 1979 the disease had been
Indigenous people of Oaxaca the Spanish in August 1521. The Spanish crown granted Oaxaca to the conquistador Hernán Cortés as his prize. The Spanish introduced new food such as wheat and sugar cane and new methods of cultivation. Diseases introduced by the Spanish greatly diminished the native population of Oaxaca, as did the insatiable appetite for gold, which led more and more Oaxacans into the dangerous mines. Over the 300 years of colonialism, many aspects of life became Europeanized. Important government positions were filled by the Spanish and their descendants, and later by elite mestizos, persons of mixed European and indigenous ancestry. However, Oaxaca