Refractory period (sex) for treating sexual dysfunction. Sildenafil, used in the treatment of erectile dysfunction, was found in one scientific study to have caused "a decreased postejaculatory erectile refractory time (3.2 ± 0.7 vs. 6.4 ± 0.7 minutes)" in men diagnosed with premature ejaculation. It is additionally proposed that the gonadotropin inhibitory hormone (GnIH), which is considered to inhibit the hypothalamic-pituitary-gonadal axis and sexual functions causes refractoriness of the post-ejaculatory refractory period. This hypothesis also supports the increase of oxytocin and prolactin after orgasm in accordance with the previous studies. One alternative theory explains the male refractory period in terms of a peripheral
Refractory initial bake-out of a new refractory lining on site can be a very expensive and time-consuming component of a refractory repair project. The use of precast and prefired refractory shapes can sometimes reduce or even eliminate the need for an extensive initial bake-out. If an entire repair is made with a prefired system, then normal furnace start up schedules can be used, without the fear of steam spalls or other damage during the initial heating. Bake-out of multi-component linings, which may include a combination of precast shapes and other materials placed in the field, can often be reduced by the