Lewis acids and bases ionic bonding. Classically, the term "Lewis acid" is restricted to trigonal planar species with an empty p orbital, such as BR where R can be an organic substituent or a halide. For the purposes of discussion, even complex compounds such as EtAlCl and AlCl are treated as trigonal planar Lewis acids. Metal ions such as Na, Mg, and Ce, which are invariably complexed with additional ligands, are often sources of coordinatively unsaturated derivatives that form Lewis adducts upon reaction with a Lewis base[citation needed]. Other reactions might simply be referred to as "acid-catalyzed" reactions. Some compounds, such as HO, are
Chemical substance discovery of many more chemical elements and new techniques in the realm of analytical chemistry used for isolation and purification of elements and compounds from chemicals that led to the establishment of modern chemistry, the concept was defined as is found in most chemistry textbooks. However, there are some controversies regarding this definition mainly because the large number of chemical substances reported in chemistry literature need to be indexed. Isomerism caused much consternation to early researchers, since isomers have exactly the same composition, but differ in configuration (arrangement) of the atoms. For example, there was much speculation for the chemical