Globalization and disease Spanish soldiers introduced smallpox by contact with natives of the Aztec capital Tenochtitlan. A devastating epidemic broke out among the indigenous people, killing thousands. In 1617, smallpox reached Massachusetts, probably brought by earlier explorers to Nova Scotia, Canada.” By 1638 the disease had broken out among people in Boston, Massachusetts. In 1721 people fled the city after an outbreak, but the residents spread the disease to others throughout the thirteen colonies. Smallpox broke out in six separate epidemics in the United States through 1968. The smallpox vaccine was developed in 1798 by Edward Jenner. By 1979 the disease had been
Mexican settlement in the Philippines Mexican immigrants to the Philippines, they belonged to different ethnic groups such as indigenous and mestizos and Creoles who mainly mixed with the local population, which also increased the number of descendants with Spanish surnames. The construction of the military fort of Zamboanga counted with the help of these Mexican immigrants who had already settled in the islands. The Mexican legacy in the Philippines, consisting of marriage between the Spanish and the indigenous culture of origin (Maya and Nahuatl), has been marked in these islands. Many words that originated from Nahuatl, a language spoken by the descendants of the indigenous