Indigenous peoples of the Americas Smallpox killed from one third to half of the native population of Hispaniola in 1518. By killing the Incan ruler Huayna Capac, smallpox caused the Inca Civil War of 1529–1532. Smallpox was only the first epidemic. Typhus (probably) in 1546, influenza and smallpox together in 1558, smallpox again in 1589, diphtheria in 1614, measles in 1618—all ravaged the remains of Inca culture. Smallpox killed millions of native inhabitants of Mexico. Unintentionally introduced at Veracruz with the arrival of Pánfilo de Narváez on April 23, 1520, smallpox ravaged Mexico in the 1520s, possibly killing over 150,000 in Tenochtitlán (the heartland of
History of the Squamish people Hudson's Bay Company was largely controlled by indigenous people who vastly outnumbered Europeans, the Fraser River Gold Rush brought a sharp increase of immigration, and more waves of disease. Furthermore, with the proclamation of the Colony of British Columbia, the British became more bold in attempting to assert colonial power. With expansion from the east, repeated epidemics, and sometimes violent conflict with settlers, the Sḵwx̱wú7mesh people became a minority in their own lands. By the turn of the 20th century, they were outnumbered by European and Asian settlers. With racist policies conducted by Canadian toward indigenous people in the country