Caduceus is a continuation of the older Indo-European dragon-slayer motif. Wilhelm Heinrich Roscher (1913) pointed out that the serpent as an attribute of both Hermes and Asclepius is a variant of the "pre-historic semi-chthonic serpent hero known at Delphi as Python", who in classical mythology is slain by Apollo. One Greek myth of origin of the caduceus is part of the story of Tiresias, who found two snakes copulating and killed the female with his staff. Tiresias was immediately turned into a woman, and so remained until he was able to repeat the act with the male snake seven years later.
Serpent (symbolism) of a snake-handler, and it was in serpent form that Zeus was said to have fathered Alexander upon her. Aeetes, the king of Colchis and father of the sorceress Medea, possessed the Golden Fleece. He guarded it with a massive serpent that never slept. Medea, who had fallen in love with Jason of the Argonauts, enchanted it to sleep so Jason could seize the Fleece. (See Lamia (mythology)). When not driven by horses, the chariot of the Greek sun god is described as being pulled by fiery draconic beings. The most notable instance of this is observed in the episode