Indigenous peoples of the Americas Smallpox killed from one third to half of the native population of Hispaniola in 1518. By killing the Incan ruler Huayna Capac, smallpox caused the Inca Civil War of 1529–1532. Smallpox was only the first epidemic. Typhus (probably) in 1546, influenza and smallpox together in 1558, smallpox again in 1589, diphtheria in 1614, measles in 1618—all ravaged the remains of Inca culture. Smallpox killed millions of native inhabitants of Mexico. Unintentionally introduced at Veracruz with the arrival of Pánfilo de Narváez on April 23, 1520, smallpox ravaged Mexico in the 1520s, possibly killing over 150,000 in Tenochtitlán (the heartland of
Indigenous people of Oaxaca Indigenous people of Oaxaca The Indigenous people of Oaxaca are descendants of the inhabitants of what is now the state of Oaxaca, Mexico who were present before the Spanish invasion. Several cultures flourished in the ancient region of Oaxaca from as far back as 2000 BC, of whom the Zapotecs and Mixtecs were perhaps the most advanced, with complex social organization and sophisticated arts. According to the National Commission for the Development of the Indigenous Peoples (CDI) Oaxaca has the greatest percentage of indigenous people after Yucatán, at 48% of the population. There are 16 formally registered indigenous communities, some