Population history of indigenous peoples of the Americas scope of the epidemics over the years was tremendous, killing millions of people—possibly in excess of 90% of the population in the hardest hit areas—and creating one of "the greatest human catastrophe in history, far exceeding even the disaster of the Black Death of medieval Europe", which had killed up to one-third of the people in Europe and Asia between 1347 and 1351. One of the most devastating diseases was smallpox, but other deadly diseases included typhus, measles, influenza, bubonic plague, cholera, malaria, tuberculosis, mumps, yellow fever and pertussis, which were chronic in Eurasia. This transfer of disease between the
Genocide of indigenous peoples toll in subsequent centuries. As detailed in "American Philosophy: From Wounded Knee to the Present", "It is also apparent that the shared history of the hemisphere is one framed by the dual tragedies of genocide and slavery, both of which are part of the legacy of the European invasions of the past 500 years. Indigenous people north and south were displaced, died of disease, and were killed by Europeans through slavery, rape, and war. In 1491, about 145 million people lived in the western hemisphere. By 1691, the population of indigenous Americans had declined by 90-95 percent, or by around