Globalization and disease Eurasian diseases to the Americas was that many more native peoples were killed by disease and germs than by the colonists' use of guns or other weapons. Scholars estimate that over a period of four centuries, epidemic diseases wiped out as much as 90 percent of the American indigenous populations. In Europe during the age of exploration, diseases such as smallpox, measles and tuberculosis (TB) had already been introduced centuries before through trade with Asia and Africa. People had developed some antibodies to these and other diseases from the Eurasian continent. When the Europeans traveled to new lands, they carried
Genocide of indigenous peoples toll in subsequent centuries. As detailed in "American Philosophy: From Wounded Knee to the Present", "It is also apparent that the shared history of the hemisphere is one framed by the dual tragedies of genocide and slavery, both of which are part of the legacy of the European invasions of the past 500 years. Indigenous people north and south were displaced, died of disease, and were killed by Europeans through slavery, rape, and war. In 1491, about 145 million people lived in the western hemisphere. By 1691, the population of indigenous Americans had declined by 90-95 percent, or by around