Dysphoric milk ejection reflex to nipple/areolar stimulation, thoughts of the baby or of breastfeeding, or overfull breasts, travels through both brain and bloodstream, causing emotional changes in the brain and the release of milk in the breast. Prolactin, released in a gradual wave that peaks after the beginning of a feeding, is responsible for continued milk production. Dopamine inhibits the release of prolactin, so dopamine levels must drop in order for prolactin levels to rise. Some speculate that the necessary dopamine drop is similar to (and timed with) the oxytocin spike – a sort of negative image – but that in D-MER mothers it
Human milk microbiome in mature milk. Taxonomic composition of human milk also varies across the lactation period, initially dominated by "Weisella, Leuconostoc, Staphylococcus, Streptococcus," and "Lactococcus" species, and later composed primarily of "Veillonella, Prevotella, Leptotrichia, Lactobacillus, Streptococcus, Bifidobacterium," and "Enterococcus" Human milk oligosaccharides, a primary component of human milk, are prebiotics which have been shown to promote growth of beneficial "Bifidobacterium" and "Bacteroides" species. Mode of delivery may influence composition of the human milk microbiome, vaginal births being associated with high taxonomic diversity and high prevalence of "Bifidobacterium" and "Lactobacillus," and the opposite trend being seen with Cesarean births, however, no relationship between