Dysphoric milk ejection reflex to nipple/areolar stimulation, thoughts of the baby or of breastfeeding, or overfull breasts, travels through both brain and bloodstream, causing emotional changes in the brain and the release of milk in the breast. Prolactin, released in a gradual wave that peaks after the beginning of a feeding, is responsible for continued milk production. Dopamine inhibits the release of prolactin, so dopamine levels must drop in order for prolactin levels to rise. Some speculate that the necessary dopamine drop is similar to (and timed with) the oxytocin spike – a sort of negative image – but that in D-MER mothers it
Refractory period (sex) to a highly energetic post-orgasmic state. According to some studies, 18-year-old males have a refractory period of about 15 minutes, while those in their 70s take about 20 hours, with the average for all men being about half an hour. Although rarer, some males exhibit no refractory period or a refractory period lasting less than 10 seconds. A scientific study attempting to document natural, fully ejaculatory, multiple orgasms in an adult man was conducted at Rutgers University in 1995. During the study, six fully ejaculatory orgasms were experienced in 36 minutes, with no apparent refractory period. Later, P. Haake "et