Agave tequilana planting these shoots; this has led to a considerable loss of genetic diversity in cultivated blue agave. It is rarely kept as a houseplant, but a 50-year-old blue agave in Boston grew a stalk requiring a hole in the greenhouse roof and flowered in the summer of 2006. Tequila is made only from a specific cultivar of "Agave tequilana" called 'Weber Azul'. This cultivar is larger and blue-gray in color compared to the smaller and green normal "A. tequilana". It is a rapid grower and prolific offsetter in keeping with its agricultural advantages. Tequila is produced by removing the heart
Alcoholic drink and fat oxidation. Ethanol is directly processed in the liver to acetyl CoA, the same intermediate product as in glucose metabolism. Because ethanol is mostly metabolized and consumed by the liver, chronic excessive use can lead to fatty liver. This leads to a chronic inflammation of the liver and eventually alcoholic liver disease. The average number of people who drink was 39% for males and 25% for females (2.4 billion people in total). Females on average drink 0.7 drinks per day while males drink 1.7 drinks per day. The rates of drinking varies significantly in different areas of the world.