Corrosive substance or slowly over days or years, e.g. the rusting of iron in a bridge. Sometimes the word caustic is used as a synonym for "corrosive", but "caustic" refers only to strong bases, particularly alkalis, and not to acids, oxidizers, or other non-alkaline corrosives. At low concentrations, a corrosive substance is called an irritant, and its effect on living tissue is called irritation. At high concentrations, a corrosive substance causes a chemical burn, a distinct type of tissue damage. Corrosives are different from poisons in that corrosives are immediately dangerous to the tissues they contact, whereas poisons may have systemic toxic
Chemical safety assessment the European Chemicals Agency as part of the respective registration dossier. The purpose is to ensure that the risks related to the substance are controlled. The chemical safety assessment of a substance comprises the following steps: The European Chemicals Agency (ECHA) has developed a software tool to support industry in preparing a Chemical Safety Assessment (CSA) and Chemical Safety Report (CSR). Chesar Beta version can be downloaded from the Chesar website. Chemical Safety Reports are the main end point for data assessment under REACH (the European Community Regulation on chemicals and their safe use, concerning the Registration, Evaluation, Authorisation and