Indigenous peoples of the Americas Smallpox killed from one third to half of the native population of Hispaniola in 1518. By killing the Incan ruler Huayna Capac, smallpox caused the Inca Civil War of 1529–1532. Smallpox was only the first epidemic. Typhus (probably) in 1546, influenza and smallpox together in 1558, smallpox again in 1589, diphtheria in 1614, measles in 1618—all ravaged the remains of Inca culture. Smallpox killed millions of native inhabitants of Mexico. Unintentionally introduced at Veracruz with the arrival of Pánfilo de Narváez on April 23, 1520, smallpox ravaged Mexico in the 1520s, possibly killing over 150,000 in Tenochtitlán (the heartland of
Caeté people Caeté people The Caetés (Kaeté) were an indigenous people of Brazil, linguistically belonging to the Tupi people. The Tupi people were a large group of indigenous people who populated Brazil's coast, and they were among the first natives that the Portuguese encountered when they arrived at South America. The Tupi were divided into several tribes such as the: Tupiniquim, Tupinambá, Potiguara, Tabajara, Temiminó, Tamoios, and the Caeté. This tribe was estimated to contain approximately 300-2,000 people in the early 1500s, but their population eventually diminished greatly due to European diseases and slavery once the Portuguese began to settle in Brazil.