Refractory period (sex) for treating sexual dysfunction. Sildenafil, used in the treatment of erectile dysfunction, was found in one scientific study to have caused "a decreased postejaculatory erectile refractory time (3.2 ± 0.7 vs. 6.4 ± 0.7 minutes)" in men diagnosed with premature ejaculation. It is additionally proposed that the gonadotropin inhibitory hormone (GnIH), which is considered to inhibit the hypothalamic-pituitary-gonadal axis and sexual functions causes refractoriness of the post-ejaculatory refractory period. This hypothesis also supports the increase of oxytocin and prolactin after orgasm in accordance with the previous studies. One alternative theory explains the male refractory period in terms of a peripheral
Refractory period (sex) Refractory period (sex) In human sexuality, the refractory period is usually the recovery phase after orgasm during which it is physiologically impossible for a man to have additional orgasms. This phase begins immediately after ejaculation and lasts until the excitement phase of the human sexual response cycle begins anew with low level response. Although it is generally reported that women do not experience a refractory period and can thus experience an additional orgasm (or multiple orgasms) soon after the first one, some sources state that both men and women experience a refractory period because women may also experience a moment