Globalization and disease Spanish soldiers introduced smallpox by contact with natives of the Aztec capital Tenochtitlan. A devastating epidemic broke out among the indigenous people, killing thousands. In 1617, smallpox reached Massachusetts, probably brought by earlier explorers to Nova Scotia, Canada.” By 1638 the disease had broken out among people in Boston, Massachusetts. In 1721 people fled the city after an outbreak, but the residents spread the disease to others throughout the thirteen colonies. Smallpox broke out in six separate epidemics in the United States through 1968. The smallpox vaccine was developed in 1798 by Edward Jenner. By 1979 the disease had been
Indigenous people in video gaming depicted Indigenous people were misrepresented and perpetuated negative post-colonial stereotypes (see Custer's Revenge). Video games created by Indigenous people enable the creators to self-determine how they are represented and enables Indigenous people to picture themselves in the future. Indigenous people have been involved in a range of projects where they have the opportunity to depict themselves. These games range in the style of the collaboration from games that consult with a single Indigenous person to games that are entirely developed and designed by Indigenous people. There are Indigenous people working on a range of large blockbusters to small indie collaborations.