Population history of indigenous peoples of the Americas scope of the epidemics over the years was tremendous, killing millions of people—possibly in excess of 90% of the population in the hardest hit areas—and creating one of "the greatest human catastrophe in history, far exceeding even the disaster of the Black Death of medieval Europe", which had killed up to one-third of the people in Europe and Asia between 1347 and 1351. One of the most devastating diseases was smallpox, but other deadly diseases included typhus, measles, influenza, bubonic plague, cholera, malaria, tuberculosis, mumps, yellow fever and pertussis, which were chronic in Eurasia. This transfer of disease between the
Influx of disease in the Caribbean almost assured the likelihood that people in these areas would be exposed to the diseases. While the Africans were genetically protected, the Europeans were not. Many Europeans living in the new lands would contract the diseases and die. The resistance of Africans to these diseases, which allowed them to survive and work in infested areas where Europeans couldn't, ironically increased their usefulness there and caused increased slave trade. The introduction of these two diseases into the Caribbean changed the ethnic makeup of the area, and decimating the indigenous population. Influx of disease in the Caribbean The Atlantic slave trade brought