Ignition timing Ignition timing In a spark ignition internal combustion engine, Ignition timing refers to the timing, relative to the current piston position and crankshaft angle, of the release of a spark in the combustion chamber near the end of the compression stroke. The need for advancing (or retarding) the timing of the spark is because fuel does not completely burn the instant the spark fires, the combustion gases take a period of time to expand and the angular or rotational speed of the engine can lengthen or shorten the time frame in which the burning and expansion should occur. In a
Carbohydrate-responsive element-binding protein Carbohydrate-responsive element-binding protein Carbohydrate-responsive element-binding protein (ChREBP) also known as MLX-interacting protein-like (MLXIPL) is a protein that in humans is encoded by the "MLXIPL" gene. The protein name derives from the protein's interaction with carbohydrate response element sequences of DNA. This gene encodes a basic helix-loop-helix leucine zipper transcription factor of the Myc / Max / Mad superfamily. This protein forms a heterodimeric complex and binds and activates, in a glucose-dependent manner, carbohydrate response element (ChoRE) motifs in the promoters of triglyceride synthesis genes. This gene is deleted in Williams-Beuren syndrome, a multisystem developmental disorder caused by the deletion of