Globalization and disease Spanish soldiers introduced smallpox by contact with natives of the Aztec capital Tenochtitlan. A devastating epidemic broke out among the indigenous people, killing thousands. In 1617, smallpox reached Massachusetts, probably brought by earlier explorers to Nova Scotia, Canada.” By 1638 the disease had broken out among people in Boston, Massachusetts. In 1721 people fled the city after an outbreak, but the residents spread the disease to others throughout the thirteen colonies. Smallpox broke out in six separate epidemics in the United States through 1968. The smallpox vaccine was developed in 1798 by Edward Jenner. By 1979 the disease had been
National Institute of Indigenous Peoples National Institute of Indigenous Peoples The National Institute of Indigenous Peoples (, INPI) is a decentralized agency of the Mexican Federal Public Administration. It was established on December 4, 2018, though the earliest Mexican government agency for indigenous matters was created in 1948. It is headquartered in Mexico City and headed by Adelfo Regino Montes. The National Indigenist Institute was established in 1948, with the initial goal of integrating indigenous people into the national culture. The agency carried out health and education campaigns, and it also relocated more than 22,000 people displaced by the construction of the Miguel Alemán Dam