Indigenous peoples of the Americas Smallpox killed from one third to half of the native population of Hispaniola in 1518. By killing the Incan ruler Huayna Capac, smallpox caused the Inca Civil War of 1529–1532. Smallpox was only the first epidemic. Typhus (probably) in 1546, influenza and smallpox together in 1558, smallpox again in 1589, diphtheria in 1614, measles in 1618—all ravaged the remains of Inca culture. Smallpox killed millions of native inhabitants of Mexico. Unintentionally introduced at Veracruz with the arrival of Pánfilo de Narváez on April 23, 1520, smallpox ravaged Mexico in the 1520s, possibly killing over 150,000 in Tenochtitlán (the heartland of
Genocide of indigenous peoples to the conquering of the Americas, Africa, Australia, and Asia. This period of expansion resulted in several instances of massacres, and genocide. Many indigenous peoples, such as the Yuki, the Pallawah and Herero, were brought to the brink of extinction. In some cases, entire tribes were annihilated. From the colonial period of the early 1500s through the twentieth century, the indigenous peoples of the Americas have experienced massacres, torture, terror, sexual abuse, systematic military occupations, removals of Indigenous peoples from their ancestral territories, forced removal of Native American children to military-like boarding schools, allotment, and a policy of termination. Historians