Lewis acids and bases ionic bonding. Classically, the term "Lewis acid" is restricted to trigonal planar species with an empty p orbital, such as BR where R can be an organic substituent or a halide. For the purposes of discussion, even complex compounds such as EtAlCl and AlCl are treated as trigonal planar Lewis acids. Metal ions such as Na, Mg, and Ce, which are invariably complexed with additional ligands, are often sources of coordinatively unsaturated derivatives that form Lewis adducts upon reaction with a Lewis base[citation needed]. Other reactions might simply be referred to as "acid-catalyzed" reactions. Some compounds, such as HO, are
Substance of very high concern must be submitted to the ECHA. Substance of very high concern A substance of very high concern (SVHC) is a chemical substance (or part of a group of chemical substances) for which it has been proposed that the use within the European Union be subject to authorisation under the REACH Regulation. Indeed, listing of a substance as an SVHC by the European Chemicals Agency (ECHA) is the first step in the procedure for restriction of use of a chemical. The first list of SVHCs was published on 28 October 2008 and the list has been updated many times to include