Globalization and disease Spanish soldiers introduced smallpox by contact with natives of the Aztec capital Tenochtitlan. A devastating epidemic broke out among the indigenous people, killing thousands. In 1617, smallpox reached Massachusetts, probably brought by earlier explorers to Nova Scotia, Canada.” By 1638 the disease had broken out among people in Boston, Massachusetts. In 1721 people fled the city after an outbreak, but the residents spread the disease to others throughout the thirteen colonies. Smallpox broke out in six separate epidemics in the United States through 1968. The smallpox vaccine was developed in 1798 by Edward Jenner. By 1979 the disease had been
History of Mexican Americans in Texas outnumbered non-Hispanic white births since the early 1990s. In 2007, for the first time since the early nineteenth century, Hispanics accounted for more than half of all births (50.2%), while non-Hispanic whites accounted for just 34%. History of Mexican Americans in Texas Indigenous peoples lived in the area now known as Texas long before Spanish explorers arrived in the area. However, once Spaniards arrived and claimed the area for Spain, a process known as "mestizaje" occurred, in which Spaniards and Native Americans had "mestizo" children who had both Spanish and indigenous blood. Texas was ruled by Spain as part of