Globalization and disease Spanish soldiers introduced smallpox by contact with natives of the Aztec capital Tenochtitlan. A devastating epidemic broke out among the indigenous people, killing thousands. In 1617, smallpox reached Massachusetts, probably brought by earlier explorers to Nova Scotia, Canada.” By 1638 the disease had broken out among people in Boston, Massachusetts. In 1721 people fled the city after an outbreak, but the residents spread the disease to others throughout the thirteen colonies. Smallpox broke out in six separate epidemics in the United States through 1968. The smallpox vaccine was developed in 1798 by Edward Jenner. By 1979 the disease had been
Indigenous peoples of Florida Indigenous peoples of Florida The Indigenous peoples of Florida lived in what is now known as Florida for more than 12,000 years before the time of first contact with Europeans. However, the indigenous Floridians have largely died out with some completely by the early 18th century. Some Apalachees migrated to Louisiana, where their descendants now live, some were taken to Cuba and Mexico by the Spanish in the 18th century, and a few may have been absorbed into the Seminole and Miccosukee tribes. The first people arrived in Florida before the extinction of the Pleistocene megafauna. Human remains and/or artifacts