Globalization and disease Eurasian diseases to the Americas was that many more native peoples were killed by disease and germs than by the colonists' use of guns or other weapons. Scholars estimate that over a period of four centuries, epidemic diseases wiped out as much as 90 percent of the American indigenous populations. In Europe during the age of exploration, diseases such as smallpox, measles and tuberculosis (TB) had already been introduced centuries before through trade with Asia and Africa. People had developed some antibodies to these and other diseases from the Eurasian continent. When the Europeans traveled to new lands, they carried
Indigenous peoples in Uruguay territory was inhabited by small tribes of nomadic Charrua, Chana, Arachan and Guarani peoples. They were a semi-nomadic people who survived by hunting, fishing and gathering and probably never reached more than 10,000 – 20,000 people. It is estimated that there were about 9,000 Charrúa and 6,000 Chaná and Guaraní at the time of contact with the Spanish in the 1500s. By the time of independence, some 300 years later, there were only about 500 native peoples remaining in Uruguay. The cause of the decline in native populations was disease, as well as intermarriage. With little immunity to these diseases,