Lewis acids and bases factors, in addition to electron configuration factors, play a role in determining the strength of the interaction between the bulky di-"t"-butylpyridine and tiny proton. Lewis acids and bases A Lewis acid is a chemical species that contains an empty orbital which is capable of accepting an electron pair from a Lewis base to form a Lewis adduct. A Lewis base, then, is any species that has a filled orbital containing an electron pair which is not involved in bonding but may form a dative bond with a Lewis acid to form a Lewis adduct. For example, NH is a Lewis
Chemical substance research only: The cause of the difference in production volume is the complexity of the molecular structure of the chemical. Bulk chemicals are usually much less complex. While fine chemicals may be more complex, many of them are simple enough to be sold as "building blocks" in the synthesis of more complex molecules targeted for single use, as named above. The "production" of a chemical includes not only its synthesis but also its purification to eliminate by-products and impurities involved in the synthesis. The last step in production should be the analysis of batch lots of chemicals in order to