İstiklal Avenue Art Nouveau and styles; as well as a few Art Deco style buildings from the early years of the Turkish Republic, and a number of more recent examples of modern architecture; starts from the medieval Genoese neighbourhood around Galata Tower and ultimately leads up to Taksim Square. Galatasaray Square is located at approximately the center of the avenue and is home to the oldest secondary school in Turkey: the Galatasaray High School (Galatasaray Lisesi), originally known as the "Galata Sarayı Enderun-u Hümayunu" ("Galata Palace Imperial School"). In the historic Karaköy (Galata) district towards the southern end of the avenue, it
Galata Mehmed II with the name "Galata Camii" (Galata Mosque; or alternatively "Cami-i Kebir", i.e. Great Mosque), it was given by Sultan Bayezid II to the Spanish Moors who fled the Spanish Inquisition of 1492 and came to Istanbul. In 1261, the quarter was retaken by the Byzantines, but Emperor Michael VIII Palaiologos (r. 1259–1282) granted it to the Genoese in 1267 in accordance with the Treaty of Nymphaeum. The precise limits of the Genoese colony were stipulated in 1303, and they were prohibited from fortifying it. The Genoese however disregarded this, and through subsequent expansions of the walls, enlarged the