Lewis acids and bases factors, in addition to electron configuration factors, play a role in determining the strength of the interaction between the bulky di-"t"-butylpyridine and tiny proton. Lewis acids and bases A Lewis acid is a chemical species that contains an empty orbital which is capable of accepting an electron pair from a Lewis base to form a Lewis adduct. A Lewis base, then, is any species that has a filled orbital containing an electron pair which is not involved in bonding but may form a dative bond with a Lewis acid to form a Lewis adduct. For example, NH is a Lewis
Amount of substance Amount of substance Amount of substance is a standard-defined quantity that measures the size of an ensemble of particles, such as atoms, molecules, electrons, and other particles. It is sometimes referred to as chemical amount. The International System of Units (SI) defines the amount of substance to be proportional to the number of entities present. The SI unit for amount of substance is the mole. It has the unit symbol mol. The proportionality constant is the inverse of the Avogadro constant. The mole is defined as the amount of substance that contains an equal number of elementary entities as there