Agave tequilana Through the 1990s, diseases spread, particularly "Fusarium" fungi and "Erwinia" bacteria, exacerbated by the low genetic diversity of the agave plants. Other problems include the agave weevil, "Scyphophorus acupunctatus", and a fungus, "Thielaviopsis paradoxa". According to a 2004 study, additional pathogens, "Erwinia carotovora", "Enterobacter agglomerans", "Pseudomonas mendocina", and "Serratia" spp. are responsible for continued rot. The homoisoflavanones 5,7-dihydroxy-3-(4-methoxybenzyl)-chroman-4-one, 7-hydroxy-3-(4-hydroxybenzyl)-chroman-4-one and 4’-demethyl-3,9-dihydro-punctatin can be isolated from "A. tequilana". Agave tequilana Agave tequilana, commonly called blue agave () or tequila agave, is an agave plant that is an important economic product of Jalisco, Mexico, due to its role as the base ingredient
Alcoholic drink jugs suggest that intentionally fermented drinks existed at least as early as the Neolithic period (cir. 10,000 BC). Many animals also consume alcohol when given the opportunity and are affected in much the same way as humans, although humans are the only species known to produce alcoholic drinks intentionally. Beer is a beverage fermented from grain mash. It is typically made from barley or a blend of several grains and flavored with hops. Most beer is naturally carbonated as part of the fermentation process. If the fermented mash is distilled, then the drink becomes a spirit. In the Andean region,