The Nexus Trilogy a treadmill in Kyoto, Japan. Later work done by Phillip Kennedy and colleagues built the first intracortical brain–computer interface by implanting neurotrophic-cone electrodes into one man, Johnny Ray, a stroke victim unable to move muscles below his face. With the connection made, the electrodes can record the electrical impulses that travel across neurons when thinking occurs. Those signals are transferred to a transmitter embedded beneath the scalp. Amplified 1,000 times, the signals go to a computer, which translates them into cursor movement, allowing him the ability to communicate simply by thinking. Other research has seen success with sensory data, including
Drug delivery to the brain Drug delivery to the brain Drug delivery to the brain is the process of passing therapeutically active molecules across the blood–brain barrier for the purpose of treating brain maladies. This is a complex process that must take into account the complex anatomy of the brain as well as the restrictions imposed by the special junctions of the blood–brain barrier. The blood–brain barrier is formed by special tight junctions between the epithelial cells that surround the brain tissue. All tissue is separated by this layer of epithelial cells, however only the brain epithelial cells have these tight junctions that do not