Radial glial cell the onset of gliogenesis, it is unclear whether they are involved in spinal cord neurogenesis or migration. Radial glia have also been implicated in forming boundaries between different axonal tracts and white matter areas of the brain. As radial glia serve as the primary neural and glial progenitors in the brain, as well as being crucial for proper neuronal migration, defects in radial glial function can have profound effects in the development of the nervous system. Mutations in either Lis1 or Nde1, essential proteins for radial glial differentiation and stabilization, cause the associated neurodevelopmental diseases Lissencephaly and micro-lissencephaly (which literally
Guidepost cells in the neural tube of Drosophilia available for the binding of growing axons. These studies have defined guidepost cells as non-continuous landmarks located on future paths of growing axons by providing high-affinity substrates to bind to for navigation. Guidepost cells are typically immature glial cells and neuron cells, that have yet to grown an axon. They can either be labeled as short range cells or axon dependent cells. To qualify as a guidepost cell, neurons hypothesized to be influenced by a guidance cell are examined during development. To test the guidance cell in question, neural axon growth and migration is