Calcofluor-white Calcofluor-white Calcofluor-white is a special fluorescent stain that binds strongly to structures containing cellulose and chitin. In plant cell biology research, it is used for the staining of cell walls of both algae and higher plants. It is also useful in medicine and animal biology for the identification of fungi in the tissue, (it binds to the chitin in the cell walls of the fungi). In research, calcofluor-white is also used to stain bud scars of yeast cells because the bud scars have a higher content of chitin, which stains them more than the rest of the cell membrane. Due
Polymer-drug conjugates tested in drug conjugates. Due to successful clinical proof-of-concept, second-generation conjugates are now being developed. Experimental chemotherapy and novel polymer-based combinations are currently under investigation. Instead of passive targeting developed so far, new approaches will provide receptor-mediated delivery. This will enable selective delivery of anticancer conjugates. A natural polymer dextrin and pendant chain polyacetals, have shown ability of pH-dependent degradation after incorporation into cell compartments. Also diethylstilboestrol (DES) conjugates can undergo pH-dependent degradation. Polymer-Directed Enzyme Prodrug Therapy (PDEPT) is an example of two-step anticancer treatment. Polymer-drug conjugates Polymer-drug conjugates are nano-medicine products under development for cancer diagnosis and treatment. There