Native Americans in the United States reached the West Coast in the 1770s, smallpox rapidly killed at least 30% of Northwest Coast Native Americans. For the next eighty to one hundred years, smallpox and other diseases devastated native populations in the region. Puget Sound area populations, once estimated as high as 37,000 people, were reduced to only 9,000 survivors by the time settlers arrived en masse in the mid-19th century. Smallpox epidemics in 1780–82 and 1837–38 brought devastation and drastic depopulation among the Plains Indians. By 1832, the federal government established a smallpox vaccination program for Native Americans ("The Indian Vaccination Act of 1832"). It was
Chinese Americans It is also the third largest community in the Chinese diaspora, behind the Chinese communities in Thailand and Malaysia. The 2016 Community Survey of the US Census estimates a population of Chinese Americans of one or more races to be 5,081,682 The Chinese American community comprises the largest ethnic group of Asian Americans, comprising 25.9% of the Asian American population as of 2010. Americans of Chinese descent, including those with partial Chinese ancestry constitute 1.5% of the total U.S. population as of 2017. According to the 2010 census, the Chinese American population numbered approximately 3.8 million. In 2010, half of