Charles Stent Charles Stent Charles Stent (1807–1885) was a 19th-century English dentist notable for his advances in the field of denture making. In 1847, Edwin Truman introduced gutta-percha as a material for making dental impressions; however, this was unsatisfactory for several reasons, including its tendency to distort upon removal from the patient's mouth, and to shrink upon cooling. In 1856, Stent added several other materials to the gutta-percha, notably stearine, which markedly improved the plasticity of the material as well as its stability. He also added talc as an inert filler to give more body to the material, and red colouring. The
Drug-eluting stent Drug-eluting stent A drug-eluting stent (DES) is a peripheral or coronary stent (a scaffold) placed into narrowed, diseased peripheral or coronary arteries that slowly releases a drug to block cell proliferation. This prevents fibrosis that, together with clots (thrombi), could otherwise block the stented artery, a process called restenosis. The stent is usually placed within the peripheral or coronary artery by an interventional cardiologist or interventional radiologist during an angioplasty procedure. Drug-eluting stents in current clinical use were approved by the FDA after clinical trials showed they were statistically superior to bare-metal stents for the treatment of native coronary artery