History of neuroscience that the functional unit of the brain is the neuron. Golgi and Ramón y Cajal shared the Nobel Prize in Physiology or Medicine in 1906 for their extensive observations, descriptions and categorizations of neurons throughout the brain. The hypotheses of the neuron doctrine were supported by experiments following Galvani's pioneering work in the electrical excitability of muscles and neurons. In the late 19th century, Emil du Bois-Reymond, Johannes Peter Müller, and Hermann von Helmholtz showed neurons were electrically excitable and that their activity predictably affected the electrical state of adjacent neurons. In parallel with this research, work with brain-damaged patients
Pinky and the Brain question, "Are you pondering what I'm pondering?" Pinky often points out flaws in the Brain's plans, which the Brain consistently ignores. The issues Pinky brings up can ironically lead to the downfall of the given night's plot. He is also arguably Brain's moral compass and only real friend. When Pinky sold his soul to get Brain the world in "A Pinky and the Brain Halloween", Brain saved him because he missed him and the world was not worth ruling without him. Pinky also has shown signs of intelligence despite his supposed childish stupidity. In "Welcome to the Jungle", Pinky was