History of neuroscience that the functional unit of the brain is the neuron. Golgi and Ramón y Cajal shared the Nobel Prize in Physiology or Medicine in 1906 for their extensive observations, descriptions and categorizations of neurons throughout the brain. The hypotheses of the neuron doctrine were supported by experiments following Galvani's pioneering work in the electrical excitability of muscles and neurons. In the late 19th century, Emil du Bois-Reymond, Johannes Peter Müller, and Hermann von Helmholtz showed neurons were electrically excitable and that their activity predictably affected the electrical state of adjacent neurons. In parallel with this research, work with brain-damaged patients
Pinky and the Brain mice are foiled by trying to speak "New York cabbie" and end up going in circles, the gag credit word was "anophelosis" defined as "morbid state due to extreme frustration". Another common element in nearly each episode is the following exchange (often referred to by the acronym "AYPWIP"): Brain: Pinky, are you pondering what I'm pondering?Pinky: I think so, Brain, but... Pinky's response ends with a non-sequitur such as, "we're already naked", "isn't a cucumber that small called a gherkin?" or "if they called them sad meals, kids wouldn't buy them." Brain would then become furious, often bashing Pinky over