Scoliosis polymorphisms in the "MATN1" gene (encoding for matrilin 1, cartilage matrix protein). Fifty-three single nucleotide polymorphism markers in the DNA that are significantly associated with adolescent idiopathic scoliosis were identified through a genome-wide association study. Adolescent idiopathic scoliosis has no clear causal agent, and is generally believed to be multifactorial. The prevalence of scoliosis is 1% to 2% among adolescents, but the likelihood of progression among adolescents with a Cobb angle less than 20° is about 10% to 20%. Congenital scoliosis can be attributed to a malformation of the spine during weeks three to six "in utero" due to a
How the Lack of Love Affects Two Men How the Lack of Love Affects Two Men How the Lack of Love Affects Two Men () is a 2006 South Korean film. Dong Chol-dong is a widower who lives with his only son, Dong-hyun. Chol-dong makes his living by blackmailing companies for their immoral activities, and in his spare time devotes himself to such activities as measuring the length of toilet paper, so he can sue the paper company if it is shorter than advertised. His son, Dong-hyun, is a bully who will go to any lengths to get what he wants. The lives of these two men take