Cardiovascular centre the cardiovascular centre and cause it to increase the rate of impulses sent to the sinoatrial node, or pacemaker, resulting in faster and stronger cardiac muscle contraction and thus increasing the heart rate. Cardiovascular centre The cardiovascular centre is a part of the human brain responsible for the regulation of the rate at which the heart beats through the nervous and endocrine systems. It is found in the medulla oblongata. Normally, the heart beats without nervous control, but in some situations (e.g., exercise, body trauma), the cardiovascular centre is responsible for altering the rate at which the heart beats. It
Cardiac excitation-contraction coupling into the cell. Secondly Ca indirectly activates proteins, called myofilaments, resulting in muscle contraction. The two main myofilaments in cardiac (and skeletal) muscle are actin and myosin. Ca binds to a protein called troponin, which is bound to the actin filament. This binding causes a shape change in the troponin which exposes areas on the actin, to which the head of the myosin filament binds. The binding of the myosin head to actin is known as a cross-bridge. A molecule, called adenosine triphosphate (ATP) which is produced by an intracellular structure called a mitochondrion, is then used, as a source