Glutamate receptor Glutamate receptor Glutamate receptors are synaptic and non synaptic receptors located primarily on the membranes of neuronal and glial cells. Glutamate (the conjugate base of glutamic acid) is abundant in the human body, but particularly in the nervous system and especially prominent in the human brain where it is the body's most prominent neurotransmitter, the brain's main excitatory neurotransmitter, and also the precursor for GABA, the brain's main inhibitory neurotransmitter. Glutamate receptors are responsible for the glutamate-mediated postsynaptic excitation of neural cells, and are important for neural communication, memory formation, learning, and regulation. Glutamate receptors are implicated in a number
Glial scar the spinal cord lesion and this decrease was associated with a reduction in glial scarring. Chondroitinase ABC has been shown to degrade glial scars. Degrading the glial scar with chondroitinase has been shown to promote recovery from spinal cord injury, especially when combined with other techniques such as nerve guidance conduits, schwann cell transplants, and peripheral nerve autografts. Glial scar Glial scar formation (gliosis) is a reactive cellular process involving astrogliosis that occurs after injury to the central nervous system. As with scarring in other organs and tissues, the glial scar is the body's mechanism to protect and begin the