Jan F. Esser Jan F. Esser Johannes "Jan" Fredericus Samuel Esser (13 October 1877 in Leiden – 9 August 1946 in Chicago) was a Dutch plastic surgeon who pioneered innovative methods of reconstructive surgery on soldiers wounded in the First World War. He is thought to have coined the term "stent" in 1917 to describe his use of a dental impression compound invented in 1856 by the English dentist Charles Stent (1807–1885) to create a form for facial reconstruction. The term "stent" was later extended to mean a device to expand constricted tubes of body tissue. He was a one time Dutch Chess
Drug-eluting stent placement, and anticlotting agents should be continued; the question is for how long. Coronary arterial healing occurs after the placement of a drug-eluting stent, but complete healing of the vessel takes time. For drug-eluting stents, the time course of complete healing in humans is unknown. A stent is a foreign object in the body, and the body responds to the stent’s presence in a variety of ways. Macrophages accumulate around the stent, and nearby smooth muscle cells proliferate. These physiological changes, which can cause restenosis, are limited by the drugs released by the stent, but these drugs also limit formation