Glial fibrillary acidic protein rodent brain. These isoforms include GFAP kappa, GFAP +1 and the currently best researched GFAP delta. GFAP delta appears to be linked with neural stem cells (NSCs) and may be involved in migration. GFAP+1 is an antibody which labels two isoforms. Although GFAP+1 positive astrocytes are supposedly not reactive astrocytes, they have a wide variety of morphologies including processes of up to 0.95mm (seen in the human brain). The expression of GFAP+1 positive astrocytes is linked with old age and the onset of AD pathology. Glial fibrillary acidic protein Glial fibrillary acidic protein (GFAP) is a protein that is encoded
Perisynaptic schwann cells research conducted in the past two decades. The origin of Perisynaptic (Terminal) Schwann Cells was largely under question in the 1960s as there were arguments on whether the cells were of epithelial or glial descent, but the development of PSCs has been linked to Neural crest origin. As described above, PSCs are a type of non-myelinating Schwann cell, which develop from neural crest cells. The general series of developmental events can be summarized as this: Neural Crest cells develop into Schwann cell precursors which further develop into Immature Schwann cells which then differentiate into Myelinating Schwann cells and non-Myelinating schwann