Scoliosis polymorphisms in the "MATN1" gene (encoding for matrilin 1, cartilage matrix protein). Fifty-three single nucleotide polymorphism markers in the DNA that are significantly associated with adolescent idiopathic scoliosis were identified through a genome-wide association study. Adolescent idiopathic scoliosis has no clear causal agent, and is generally believed to be multifactorial. The prevalence of scoliosis is 1% to 2% among adolescents, but the likelihood of progression among adolescents with a Cobb angle less than 20° is about 10% to 20%. Congenital scoliosis can be attributed to a malformation of the spine during weeks three to six "in utero" due to a
Sound Affects was vindicated when "Start!" topped the British singles charts in its third week after entering at number 3. "Pretty Green" includes a funk bassline and rhythm with melodic guitar breaks and psychedelic sound effects. "That's Entertainment" is an acoustic ballad. "Boy About Town" and "Dream Time" include horns. In 2006, "Q" magazine placed the album at No. 15 in its list of "40 Best Albums of the '80s". NME ranked the album No. 487 on their list of 500 Greatest Albums of All Time. "Sound Affects" spent 19 weeks on the UK album charts, rising to No. 2 in late