Serpula himantioides due to a lack of any above ground symptoms of disease. Signs of the pathogen include basidiospores, and fungal masses that are generally dark brown and membranous in the center but become thin white mycelium towards edges of the mass. The brown cubical rot caused by "S. himantioides" resembles the rots of "Phaeolus schweinitzii" and "S. lacrymans". "Serpula himantiodes" is a pre-harvest pathogen that exerts economic impact on lumber supply. It is considered the wild sister species of "S. lacrymans", the pathogen that causes dry rot in wooden building structures. "S. himantioides" is studied most frequently in the context of
Atromentin 4-HPP to observe the formation of atromentin. This was followed by characterization of the enzyme GreA in "Suillus grevillei", six (InvA1-6, of which InvA1, 2 and 5 were functional) in "Paxillus involutus", and NPS3 from "Serpula lacrymans". In addition, there is another adjacent and conserved gene encoding for an alcohol dehydrogenase/oxidoreductase whose function is unclear. In most cases the clustered biosynthetic genes are found orthologous in basidiomycetes. A common promoter motif was found shared between the atromentin synthetase and aminotransferase of 23 different atromentin-producing basidiomycetes that was in almost all cases absent from the alcohol dehydrogenase, indicating co-regulation of the