Kinetic Isotope Effects of RuBisCO carbon, oxygen, and/or hydrogen, though currently only a significant isotope effect is seen for carbon isotope substitution. Isotopes are atoms that have the same number of protons but varying numbers of neutrons. "Lighter" isotopes (like the stable Carbon-12 isotope) have a smaller overall mass, and "heavier" isotopes (like the stable Carbon-13 isotope or radioactive Carbon-14 isotope) have a larger overall mass. Stable isotope geochemistry is concerned with how varying chemical and physical processes preferentially enrich or deplete stable isotopes. Enzymes like RuBisCO cause isotopic fractionation because molecules containing lighter isotopes have higher zero-point energies (ZPE), the lowest possible quantum energy
Tritium 65 nuclear sites in the US. In one case, leaking water contained of tritium per litre, which is 375 times the EPA limit for drinking water. The US Nuclear Regulatory Commission states that in normal operation in 2003, 56 pressurized water reactors released of tritium (maximum: 2,080 Ci; minimum: 0.1 Ci; average: 725 Ci) and 24 boiling water reactors released (maximum: 174 Ci; minimum: 0 Ci; average: 27.7 Ci), in liquid effluents. According to the U.S. Environmental Protection Agency, self-illuminating exit signs improperly disposed in municipal landfills have been recently found out to contaminate waterways. The legal limits for tritium