Mechanism of anoxic depolarization in the brain intracellular Na and Ca ions, and extracellular glutamate and aspartate. Glutamate and aspartate are normally present as the brain's primary excitatory neurotransmitters, but high concentrations activate a number of downstream apoptotic and necrotic pathways. This results in neuronal dysfunction and death. Neurons function in the central nervous system by generating signals from synapses, and this only works in the proper chemical environment. An electrical signal is mediated by the sodium channels and leaky potassium channels in which intracellular K ion concentration is higher than its corresponding extracellular concentration, whereas extracellular concentrations of Na, Ca, and Cl ions are higher than
Educational neuroscience In return, it is difficult for neuroscientists to characterize such interactions in a research setting. The Horizontal Problem: Translating research findings: While education theory and data are almost exclusively behavioral, findings from neuroscience research can take on many forms (e.g. electrical, chemical, spatial, temporal etc.). The most common form of data taken from neuroscience to education is the spatial mapping of brain activation to cognitive function. Willingham (2009) highlights the difficulty in applying such spatial information to educational theory. If a certain brain region is known to support a cognitive function relevant for education, what can actually be done with