Serpula lacrymans 2016). The genus "Serpula", including "S. lacrymans" and "S. himantoides", is known to produce three classes of chemical compounds: pulvinic acid-type family, himanimides, and polyine acids. Within the pulvinic acid-type family, atromentin-derived compounds include variegatic acid, xerocomic acid, isoxerocomic acid, atromentic acid, variegatorubin, xerocomorubin, and other variants of these pigments. Pulvinic acid-type family pigments were found to be secreted during co-incubation with various bacteria. Serpula lacrymans Serpula lacrymans is one of the fungi that cause damage to timber referred to as dry rot. It is a basidiomycete in the order Boletales. The species was first described under the name "Boletus
Serpula lacrymans of 13805 genes. "S. lacrymans"' genome encodes six annotated polyketide synthases (PKS1-PKS6), 15 nonribosomal peptide synthetases (NPS1-NPS4, NPS7, NPS13-NPS15, NPS17, and NPS18), and two hybrids thereof (NPS6, NPS8, and NPS16). Additionally, the genome encodes for various putative adenylate-forming reductases (NPS5, NPS9-NPS12) (Eastwood et al., 2011). "NPS3" was overexpressed in E. coli and characterized as an atromentin/quinone synthetase that catalyzes the formation of atromentin, similar to GreA; InvA1,2 and 5; and AtrA from Suillus grevillei, Tapinella panuoides, Paxillus involutus, respectively. "NPS3" and its adjacent clustered aminotransferase gene ("AMT1") were also found to be up-regulated during co-incubation with bacteria (Tauber et al.,