Anti-transglutaminase antibodies antigen, presented by MHC molecules (HLA in humans) on antigen-reactive B-cells. These T-helper cells then stimulate B-cells to multiply and mature into plasma cells that make IgA and IgG to that protein. In the case of celiac disease, the current understanding is that tTG autoimmunity arises when T-cells are generated against wheat gliadin and similar gluten proteins made by a class of grasses called "Triticeae", which includes wheat (See Wheat taxonomy), barley, and rye. The T-cells are defined by the ability to react to HLA-DQ8 and DQ2.5 restricted antigens and gliadin is one of the antigens. Gliadin is a favored
Corn gluten meal Corn gluten meal Corn gluten meal (CGM) is the principal protein of corn (maize) endosperm consisting mainly of zein and glutelin. It is a byproduct of corn processing that has historically been used as an animal feed. Despite the name, "corn gluten" does not contain true gluten, which is formed by the interaction of gliadin and glutenin proteins. In 1985, Dr. Nick Christians of Iowa State University discovered that CGM displayed pre-emergent herbicidal effects during a series of turf grass experiments. The use of corn gluten meal as an herbicide was patented in 1991, but, like many food-related substances used