Action potential the muscle to contract. Muscle action potentials are provoked by the arrival of a pre-synaptic neuronal action potential at the neuromuscular junction, which is a common target for neurotoxins. Plant and fungal cells are also electrically excitable. The fundamental difference from animal action potentials is that the depolarization in plant cells is not accomplished by an uptake of positive sodium ions, but by release of negative "chloride" ions. Together with the following release of positive potassium ions, which is common to plant and animal action potentials, the action potential in plants infers, therefore, an osmotic loss of salt (KCl), whereas
Systole Systole of the heart is initiated by electrically excitable cells situated in the sinoatrial node. These cells are activated spontaneously by depolarization of the electrical potential across their cell membranes, which causes voltage-gated calcium channels on the cell membrane to open and allow calcium ions to pass through into the sarcoplasm (cytoplasm) of cardiac muscle cells. Calcium ions bind to molecular receptors on the sarcoplasmic reticulum (see graphic), which causes a flux (flow) of calcium ions into the sarcoplasm. Calcium ions bind to troponin C, causing a conformational (i.e., structural) change in the troponin-tropomyosin protein complex, causing the myosin head