Scoliosis polymorphisms in the "MATN1" gene (encoding for matrilin 1, cartilage matrix protein). Fifty-three single nucleotide polymorphism markers in the DNA that are significantly associated with adolescent idiopathic scoliosis were identified through a genome-wide association study. Adolescent idiopathic scoliosis has no clear causal agent, and is generally believed to be multifactorial. The prevalence of scoliosis is 1% to 2% among adolescents, but the likelihood of progression among adolescents with a Cobb angle less than 20° is about 10% to 20%. Congenital scoliosis can be attributed to a malformation of the spine during weeks three to six "in utero" due to a
Body without organs But every actual body also has a virtual dimension: a vast reservoir of potential traits, connections, affects, movements, etc. This collection of potentials is what Deleuze calls the BwO. The full body without organs is "schizophrenia as a clinical entity" ("Anti-Oedipus," p. 310). This drop in intensity is a means of blocking all investments of reality: "the unproductive, the sterile, the unengendered, the unconsumable" ("Anti-Oedipus," p. 9). Unlike other social machines such as the Body of the Earth, the Body of the Despot or the Body of Capital, the full body without organs cannot inscribe other bodies. The body without