Glial scar shown to stimulate growth-inhibitory proteoglycans by astrocytes. Experimental reduction of TGFβ-1 and TGFβ-2 has been shown to partially reduce glial scarring. Interleukins are another potential family of scar-inducing cellular messengers. Particularly, interleukin-1, a protein produced by mononuclear phagocytes, helps to initiate the inflammatory response in astrocytes, leading to reactive astrogliosis and the formation of the glial scar. The cytokine family of glial scar inducers include interferon-γ (IFNγ) and fibroblast growth factor 2 (FGF2). IFNγ has been shown to induce astrocyte proliferation and increase the extent of glial scarring in injured brain models. Further, FGF2 production increases after injury to the
101 Things Removed from the Human Body 101 Things Removed from the Human Body 101 Things Removed from the Human Body and 101 More Things Removed from the Human Body is a British "shockumentary" series directed by Eric Schotz, which is narrated by Mitch Lewis. The program features tales of foreign objects that have been removed from human bodies in the form of a countdown from 101 to 1. Items included are javelins, a boat anchor, a bicycle pump, a bag of nails, an ice pick, and a human body. The documentary series was first broadcast on Sky One in October 2003. When the show was re-broadcast