Tree from the cinchona tree ("Cinchona") and was for a long time the remedy of choice for the treatment of malaria. Aspirin was synthesised to replace the sodium salicylate derived from the bark of willow trees ("Salix") which had unpleasant side effects. The anti-cancer drug Paclitaxel is derived from taxol, a substance found in the bark of the Pacific yew ("Taxus brevifolia"). Other tree based drugs come from the paw-paw ("Carica papaya"), the cassia ("Cassia spp."), the cocoa tree ("Theobroma cacao"), the tree of life ("Camptotheca acuminata") and the downy birch ("Betula pubescens"). The papery bark of the white birch tree
Betula utilis from snowmelt, rather than from the monsoon rains. They often have very bent growth due to the pressure of the deep winter snow in the Himalaya. Leaves are ovate, long, with serrated margins, and slightly hairy. Flowering occurs from May–July, with only a few male catkins, and short, single (sometimes paired) female catkins. The perianth has four parts in male flowers, and is absent in the female flowers. Fruits ripen in September–October. The thin, papery bark is very shiny, reddish brown, reddish white, or white, with horizontal lenticels. The bark peels off in broad, horizontal belts, making it very usable