Charles Stent Charles Stent Charles Stent (1807–1885) was a 19th-century English dentist notable for his advances in the field of denture making. In 1847, Edwin Truman introduced gutta-percha as a material for making dental impressions; however, this was unsatisfactory for several reasons, including its tendency to distort upon removal from the patient's mouth, and to shrink upon cooling. In 1856, Stent added several other materials to the gutta-percha, notably stearine, which markedly improved the plasticity of the material as well as its stability. He also added talc as an inert filler to give more body to the material, and red colouring. The
Coronary stent tendency for clots to form at the site where the stent damages the arterial wall. Since platelets are involved in the clotting process, patients must take dual antiplatelet therapy starting immediately before or after stenting: usually an ADP receptor antagonist (e.g. clopidogrel or ticagrelor) and aspirin for one year and aspirin indefinitely. In order to reduce the treatment, a new generation of stent has been developed with biodegradable polymer. However, the dual antiplatelet therapy may be insufficient to fully prevent clots that may result in stent thrombosis; these and the cell proliferation may cause the standard (“bare-metal”) stents to become