Diospyros thus avoided by most herbivores; when ripe they are eagerly eaten by many animals however, such as the rare Aders' duiker ("Cephalophus adersi"). The foliage is used as food by the larvae of numerous Lepidoptera species: Arctiidae: Geometridae: Limacodidae: Lycaenidae: Nymphalidae: Saturniidae: Tortricidae: An economically significant plant pathogen infecting many "Diospyros" species – "D. hispida", kaki persimmon ("D. kaki"), date-plum ("D. lotus"), Texas persimmon ("D. texana"), Coromandel ebony ("D. melanoxylon") and probably others – is the sac fungus "Pseudocercospora kaki", which causes a leaf spot disease. The genus includes several plants of commercial importance, either for their edible fruit (persimmons)
Diospyros medical compound betulinic acid. Extracts from "Diospyros" plants have also been proposed as novel anti-viral treatment. Though bees do not play a key role as pollinators, in plantations "Diospyros" may be of some use as honey plants. "D. mollis", locally known as "mặc nưa", is used in Vietnam to dye the famous black "lãnh Mỹ A" silk of Tân Châu district. The reverence of these trees in their native range is reflected by their use as floral emblems. In Indonesia, "D. celebica" (Makassar ebony, known locally as "eboni") is the provincial tree of Central Sulawesi, while ajan kelicung ("D. macrophylla")