Kinetic Isotope Effects of RuBisCO carbon, oxygen, and/or hydrogen, though currently only a significant isotope effect is seen for carbon isotope substitution. Isotopes are atoms that have the same number of protons but varying numbers of neutrons. "Lighter" isotopes (like the stable Carbon-12 isotope) have a smaller overall mass, and "heavier" isotopes (like the stable Carbon-13 isotope or radioactive Carbon-14 isotope) have a larger overall mass. Stable isotope geochemistry is concerned with how varying chemical and physical processes preferentially enrich or deplete stable isotopes. Enzymes like RuBisCO cause isotopic fractionation because molecules containing lighter isotopes have higher zero-point energies (ZPE), the lowest possible quantum energy
Tritium MeV. In comparison, the fusion of deuterium with tritium releases about 17.6 MeV of energy. For applications in proposed fusion energy reactors, such as ITER, pebbles consisting of lithium bearing ceramics including LiTiO and LiSiO, are being developed for tritium breeding within a helium cooled pebble bed (HCPB), also known as a breeder blanket. High-energy neutrons can also produce tritium from lithium-7 in an endothermic (net heat consuming) reaction, consuming 2.466 MeV. This was discovered when the 1954 Castle Bravo nuclear test produced an unexpectedly high yield. High-energy neutrons irradiating boron-10 will also occasionally produce tritium: A more common result