Helium-3 of the airway tree, locate unventilated defects, measure the alveolar oxygen partial pressure, and measure the ventilation/perfusion ratio. This technique may be critical for the diagnosis and treatment management of chronic respiratory diseases such as chronic obstructive pulmonary disease (COPD), emphysema, cystic fibrosis, and asthma. Production, sales and distribution of helium-3 in the United States are managed by the US Department of Energy (DOE) Isotope Program. Virtually all helium-3 used in industry today is produced from the radioactive decay of tritium. Tritium is a radioactive isotope of hydrogen and is typically produced by bombarding lithium-6 with neutrons in a nuclear
Tritium radioluminescence for night use and small lights (which need to be more reliable than battery powered lights yet not interfere with night vision or be bright enough to easily give away one's location) used mostly by military personnel fall under the latter application. Tritium lighting is made using glass tubes with a phosphor layer in them and tritium gas inside the tube. Such a tube is known as a "gaseous tritium light source" (GTLS), or "beta light" (since the tritium undergoes beta decay). The tritium in a gaseous tritium light source undergoes beta decay, releasing electrons that cause the phosphor layer