Neuron Neuron A neuron, also known as a neurone (British spelling) and nerve cell, is an electrically excitable cell that receives, processes, and transmits information through electrical and chemical signals. These signals between neurons occur via specialized connections called synapses. Neurons can connect to each other to form neural pathways, and neural circuits. Neurons are the primary components of the central nervous system, which includes the brain and spinal cord, and of the peripheral nervous system, which comprises the autonomic nervous system and the somatic nervous system. There are many types of specialized neurons. Sensory neurons respond to one particular type
Nanoparticles for drug delivery to the brain that it can bind and undergo endocytosis. Another mechanism is "adsorption mediated transcytosis", where electrostatic interactions are involved in mediating nanoparticle crossing of the BBB. Cationic nanoparticles (including cationic liposomes) are of interest for this mechanism, because their positive charges assist binding on the brain's endothelial cells. Using TAT-peptides, a cell-penetrating peptide, to functionalize the surface of cationic nanoparticles can further improve drug transport into the brain. In contrast to the above mechanisms, a delivery with magnetic fields doesn't strongly depend on the biochemistry of the brain. In this case, nanoparticles are literally pulled across the BBB via application of