Glial fibrillary acidic protein was described. Patients with GFAP astrocytopathy developed meningoencephalomyelitis with inflammation of the meninges, the brain parenchyma, and the spinal cord. About one third of cases were associated with various cancers and many also expressed other CNS autoantibodies. There are multiple disorders associated with improper GFAP regulation, and injury can cause glial cells to react in detrimental ways. Glial scarring is a consequence of several neurodegenerative conditions, as well as injury that severs neural material. The scar is formed by astrocytes interacting with fibrous tissue to re-establish the glial margins around the central injury core and is partially caused by up-regulation
101 Things Removed from the Human Body 101 Things Removed from the Human Body 101 Things Removed from the Human Body and 101 More Things Removed from the Human Body is a British "shockumentary" series directed by Eric Schotz, which is narrated by Mitch Lewis. The program features tales of foreign objects that have been removed from human bodies in the form of a countdown from 101 to 1. Items included are javelins, a boat anchor, a bicycle pump, a bag of nails, an ice pick, and a human body. The documentary series was first broadcast on Sky One in October 2003. When the show was re-broadcast