Animal mesoderm forms by enterocoelic pouching, through invagination of the endoderm. The main deuterostome phyla are the Echinodermata and the Chordata. Echinoderms are exclusively marine and include starfish, sea urchins, and sea cucumbers. The chordates are dominated by the vertebrates (animals with backbones), which consist of fishes, amphibians, reptiles, birds, and mammals. The deuterostomes also include the Hemichordata (acorn worms). The Ecdysozoa are protostomes, named after their shared trait of ecdysis, growth by moulting. They include the largest animal phylum, the Arthropoda, which contains insects, spiders, crabs, and their kin. All of these have a body divided into repeating segments, typically
Libbie Hyman masterly integration of information." Declining health did not allow her to finish the entire subject. In it she developed her scientific theory that the Phylum Chordata, including all vertebrates, was evolutionarily related to the apparently very different and very much more primitive Echinodermata, such as starfish. This group is now known as the deuterostomes. Her theory was based upon the morphological data of classical embryology, and has since been confirmed by molecular sequence analysis. In addition to her major project, Hyman extensively revised "A Laboratory Manual for Comparative Vertebrate Anatomy" in 1942 into a textbook as well as laboratory manual;