Scoliosis polymorphisms in the "MATN1" gene (encoding for matrilin 1, cartilage matrix protein). Fifty-three single nucleotide polymorphism markers in the DNA that are significantly associated with adolescent idiopathic scoliosis were identified through a genome-wide association study. Adolescent idiopathic scoliosis has no clear causal agent, and is generally believed to be multifactorial. The prevalence of scoliosis is 1% to 2% among adolescents, but the likelihood of progression among adolescents with a Cobb angle less than 20° is about 10% to 20%. Congenital scoliosis can be attributed to a malformation of the spine during weeks three to six "in utero" due to a
Sound Affects Sound Affects Sound Affects is the fifth studio album by British rock band the Jam. The cover art is a pastiche of the artwork used on various "Sound Effects" records produced by the BBC during the 1970s. It is their only album co-produced by the band, and contains the only album track co-written by the entire band, "Music for the Last Couple". The album was released on 28 November 1980. Paul Weller is known to have opined "Sound Affects" as the best album The Jam released throughout their career; freely admitting the Beatles' "Revolver" had been a major influence upon