Intercalated cells of the amygdala mPFC) in both primates and rodents, which may explain cortical control over emotional regulation processes such as extinction. Intercalated cells of the amygdala The intercalated (ITC) cells of the amygdala are a group of GABAergic neurons situated between the basolateral and central nuclei of the amygdala that are important for inhibitory control over the amygdala. ITC cells are thought to play a role as the 'off switch' for the amygdala, inhibiting the amygdala's central nucleus output neurons and its basolateral nucleus neurons. Some researchers speculate that ITC cells, via their extensive local inhibition within the amygdala, could serve as a
Electrical brain stimulation physician Luigi Galvani (1737–1798) that nerves and muscles were electrically excitable. The stimulation of the surface of the cerebral cortex by using brain stimulation was used to investigate the motor cortex in animals by researchers such as Eduard Hitzig (1838–1907), Gustav Fritsch (1838–1927), David Ferrier (1842–1928) and Friedrich Goltz (1834–1902). The human cortex was also stimulated electrically by neurosurgeons and neurologists such as Robert Bartholow (1831–1904) and Fedor Krause (1857–1937). In the following century, the technique was improved by the invention of the stereotactic method by British neurosurgeon pioneer Victor Horsley (1857–1916), and by the development of chronic electrode implants