Dead Brain Cells the name Dead Brain Cells among three suggestions by Leone, the others being "The Mental Pukes" and "The Retarded Assholes". Lowe had made commitments to his job and could not sing with the band anymore. Dakin decided he would sing and play bass at the same time. The band released two albums and toured twice in the United States. Their first album, "Dead Brain Cells", was released in 1987. It was followed by a concept album, "Universe", in 1989. Their song, "The Genesis Explosion", was featured in a Canadian television commercial for Microcell Telecommunications in 2005. The commercial depicts an
Nanoparticles for drug delivery to the brain stabilizing the nanoparticles and preventing the nanoparticles from aggregation. Metallic nanoparticles typically cross the BBB via transcytosis. Nanoparticle delivery through the BBB can be increased by introducing peptide conjugates to improve permeability to the central nervous system. For instance, recent studies have shown an improvement in gold nanoparticle delivery efficiency by conjugating a peptide that binds to the transferrin receptors expressed in brain endothelial cells. Also, solid lipid nanoparticles (SLNs) are lipid nanoparticles with a solid interior as shown in the diagram on the right. SLNs can be made by replacing the liquid lipid oil used in the emulsion process