Development of the nervous system in humans in the lower part. Neuronal migration is the method by which neurons travel from their origin or birthplace to their final position in the brain. There most common means of migration are radial and tangential migration. Neuronal precursor cells proliferate in the ventricular zone of the developing neocortex. The first postmitotic cells to migrate from the preplate which are destined to become Cajal-Retzius cells and subplate neurons. These cells do so by somal translocation. Neurons migrating with this mode of locomotion are bipolar and attach the leading edge of the process to the pia. The soma is then transported to
Electrical conduction system of the heart well as to the endocardium at the apex of the heart, then finally to the ventricular epicardium; causing its contraction. These signals are generated rhytmically, which in turn results in the coordinated rhythmic contraction and relaxation of the heart. On the microscopic level, the wave of depolarization propagates to adjacent cells via gap junctions located on the intercalated disc. The heart is a "functional syncytium" (not to be confused with a true "syncytium" in which all the cells are fused together, sharing the same plasma membrane as in skeletal muscle). In a functional syncytium, electrical impulses propagate freely between cells