Kinetic isotope effect both results are large enough to be indicative of weakening of the C-N bond in the transition state that would occur in a concerted process. Since kinetic isotope effects arise from differences in isotopic masses, the largest observable kinetic isotope effects are associated with isotopic substitutions of hydrogen with deuterium (100% increase in mass) or tritium (200% increase in mass). Kinetic isotope effects from isotopic mass ratios can be as large as 36.4 using muons. They have produced the lightest hydrogen atom, H (0.113 amu), in which an electron orbits around a positive muon (μ) "nucleus" that has a mass
On-Line Isotope Mass Separator or to the REX accelerator for acceleration to higher energies. The facility is operated by the ISOLDE Collaboration comprising CERN and 9 European countries. One of the major experiments in ISOLDE is the Miniball-setup. An upgrade of the post-acceleration system is currently on-going, ready to produce energetic Radioactive-Ion Beams (RIBs) of up to 10 MeV per nucleon in 2018. On-Line Isotope Mass Separator The On-Line Isotope Mass Separator, also known as the ISOLDE Radioactive Ion Beam Facility, is a facility located at CERN on the PS Booster. It started operating in 1967 and was rebuilt twice with major upgrades in