Spice spices. Spices were among the most demanded and expensive products available in Europe in the Middle Ages, the most common being black pepper, cinnamon (and the cheaper alternative cassia), cumin, nutmeg, ginger and cloves. Given medieval medicine's main theory of humorism, spices and herbs were indispensable to balance "humors" in food, a daily basis for good health at a time of recurrent pandemics. In addition to being desired by those using medieval medicine, the European elite also craved spices in the Middle Ages. An example of the European aristocracy's demand for spice comes from the King of Aragon, who invested
SPICE basis for many other circuit simulation programs, in academia, in industry, and in commercial products. The first commercial version of SPICE was ISPICE, an interactive version on a timeshare service, National CSS. The most prominent commercial versions of SPICE include HSPICE (originally commercialized by Ashawna and Kim Hailey of Meta Software, but now owned by Synopsys) and PSPICE (now owned by Cadence Design Systems). The academic spinoffs of SPICE include XSPICE, developed at Georgia Tech, which added mixed analog/digital "code models" for behavioral simulation, and Cider (previously CODECS, from UC Berkeley/Oregon State Univ.) which added semiconductor device simulation. SPICE, XSPICE