Glial fibrillary acidic protein was described. Patients with GFAP astrocytopathy developed meningoencephalomyelitis with inflammation of the meninges, the brain parenchyma, and the spinal cord. About one third of cases were associated with various cancers and many also expressed other CNS autoantibodies. There are multiple disorders associated with improper GFAP regulation, and injury can cause glial cells to react in detrimental ways. Glial scarring is a consequence of several neurodegenerative conditions, as well as injury that severs neural material. The scar is formed by astrocytes interacting with fibrous tissue to re-establish the glial margins around the central injury core and is partially caused by up-regulation
Satellite glial cell will also be explored in order to determine the effect of these conditions. Additionally, the mechanisms behind neuronal-SGC communication is essentially unidentified, though it is likely that the various receptors both the neurons and SGCs have are used for chemical signaling, perhaps with P2Y. Ca and NO and their effects must also be observed to gain further understanding of interactions between the two types of cells. Finally, the possibility of an influence of SGCs on synaptic transmission within autonomic ganglia provides another direction for future research. Satellite glial cell Satellite glial cells are glial cells that cover the surface of