Gluten-related disorders disease patients who have HLA-DQ2 and HLA-DQ8. Coeliac disease (American English: celiac) (CD) is one of the most common chronic, immune-mediated disorders, triggered by the eating of gluten, a mixture of proteins found in wheat, barley, rye and derivatives. Evidence has shown that this condition not only has an environmental component but a genetic one as well, due to strong associations of CD with the presence of HLA (Human leukocyte antigen) type II, specifically DQ2 and DQ8 alleles. These alleles can stimulate a T cell, mediated immune response against tissue transglutaminase (TTG), an enzyme in the extracellular matrix, leading to
Corn gluten meal Corn gluten meal Corn gluten meal (CGM) is the principal protein of corn (maize) endosperm consisting mainly of zein and glutelin. It is a byproduct of corn processing that has historically been used as an animal feed. Despite the name, "corn gluten" does not contain true gluten, which is formed by the interaction of gliadin and glutenin proteins. In 1985, Dr. Nick Christians of Iowa State University discovered that CGM displayed pre-emergent herbicidal effects during a series of turf grass experiments. The use of corn gluten meal as an herbicide was patented in 1991, but, like many food-related substances used