Glial scar brain and spinal cord. FGF2 has also been shown to increase astrocyte proliferation "in vitro". Ciliary neurotrophic factor (CNTF) is a cytosolic protein that is not secreted. CNTF has been shown to promote the survival of neuronal cultures "in vitro", and it can also act as a differentiator and trophic factor on glial cells. Further, CNTF has been previously shown to affect the differentiation of glial precursor cells "in vitro"; however, the influence of CNTF in the "in vivo" setting has only recently been determined. Winter "et al." used CNTF over-expressing transgenic mice as well as wildtype controls that had
Development of the human body inconsistent and contradictory; a person may be biologically an adult, and have adult behavior but still be treated as a child if they are under the legal age of majority. Conversely, one may legally be an adult but possess none of the maturity and responsibility that may define an adult. Development of human organs and organ systems begins in the embryo and continues throughout the human lifespan. Development of the human body Human development is the process of growth to maturity. The process begins with fertilisation, where an egg released from the ovary of a female is penetrated by a