History of neuroscience that the functional unit of the brain is the neuron. Golgi and Ramón y Cajal shared the Nobel Prize in Physiology or Medicine in 1906 for their extensive observations, descriptions and categorizations of neurons throughout the brain. The hypotheses of the neuron doctrine were supported by experiments following Galvani's pioneering work in the electrical excitability of muscles and neurons. In the late 19th century, Emil du Bois-Reymond, Johannes Peter Müller, and Hermann von Helmholtz showed neurons were electrically excitable and that their activity predictably affected the electrical state of adjacent neurons. In parallel with this research, work with brain-damaged patients
Excitable medium Excitable medium An excitable medium is a nonlinear dynamical system which has the capacity to propagate a wave of some description, and which cannot support the passing of another wave until a certain amount of time has passed (known as the refractory time). A forest is an example of an excitable medium: if a wildfire burns through the forest, no fire can return to a burnt spot until the vegetation has gone through its refractory period and regrown. In chemistry, oscillating reactions are excitable media, for example the Belousov–Zhabotinsky reaction and the Briggs–Rauscher reaction. Pathological activities in the heart and