Muscle contraction RyRs are activated by a calcium trigger, which is brought about by the flow of through the L-type calcium channels. Furthermore, cardiac muscle tend to exhibit diad (or dyad) structures, rather than triads. Excitation-contraction coupling in cardiac muscle cells occurs when an action potential is initiated by pacemaker cells in the sinoatrial node or Atrioventricular node and conducted to all cells in the heart via gap junctions. The action potential travels along the surface membrane into T-tubules (the latter are not seen in all cardiac cell types) and the depolarisation causes extracellular to enter the cell via L-type calcium channels
Heart rate turbulence Heart rate turbulence Heart rate turbulence (HRT) is the return to equilibrium of heart rate after a premature ventricular contraction (PVC). It consists of a brief speed-up in heart rate, followed by a slow decrease back to the baseline rate. An important feature of HRT is that PVCs occur naturally in most adults, so measuring the characteristics of a given person's HRT offers a noninvasive way to evaluate his or her cardiac function without applying artificial external stimuli. The measured values of HRT parameters have been shown to be a statistically significant predictor of the probability of dying from cardiac