Intercalated cells of the amygdala mPFC) in both primates and rodents, which may explain cortical control over emotional regulation processes such as extinction. Intercalated cells of the amygdala The intercalated (ITC) cells of the amygdala are a group of GABAergic neurons situated between the basolateral and central nuclei of the amygdala that are important for inhibitory control over the amygdala. ITC cells are thought to play a role as the 'off switch' for the amygdala, inhibiting the amygdala's central nucleus output neurons and its basolateral nucleus neurons. Some researchers speculate that ITC cells, via their extensive local inhibition within the amygdala, could serve as a
Brain tumor send the wrong chemical signals which prevent phagocytes from disposing of the dead cells, leading to a buildup of dead tissue, cell debris and toxins at or near the site of the necrotic cells Arterial and venous hypoxia, or the deprivation of adequate oxygen supply to certain areas of the brain, occurs when a tumor makes use of nearby blood vessels for its supply of blood and the neoplasm enters into competition for nutrients with the surrounding brain tissue. More generally a neoplasm may cause release of metabolic end products (e.g., free radicals, altered electrolytes, neurotransmitters), and release and recruitment