Kinetic Isotope Effects of RuBisCO carbon, oxygen, and/or hydrogen, though currently only a significant isotope effect is seen for carbon isotope substitution. Isotopes are atoms that have the same number of protons but varying numbers of neutrons. "Lighter" isotopes (like the stable Carbon-12 isotope) have a smaller overall mass, and "heavier" isotopes (like the stable Carbon-13 isotope or radioactive Carbon-14 isotope) have a larger overall mass. Stable isotope geochemistry is concerned with how varying chemical and physical processes preferentially enrich or deplete stable isotopes. Enzymes like RuBisCO cause isotopic fractionation because molecules containing lighter isotopes have higher zero-point energies (ZPE), the lowest possible quantum energy
Tritium in small quantities by some nuclear power plants. In January 2014 it was made public that a total of 875 TBq (2.45 g) of tritium are on the site of Fukushima Daiichi, and the amount of tritium contained in the contaminated water is increasing by approximately 230 TBq (0.64 g) per year. According to a report by Tepco ""Tritium could be separated theoretically, but there is no practical separation technology on an industrial scale"." Tritium's decay product helium-3 has a very large cross section for reacting with thermal neutrons, expelling a proton, hence it is rapidly converted back to tritium