Mechanism of anoxic depolarization in the brain intracellular Na and Ca ions, and extracellular glutamate and aspartate. Glutamate and aspartate are normally present as the brain's primary excitatory neurotransmitters, but high concentrations activate a number of downstream apoptotic and necrotic pathways. This results in neuronal dysfunction and death. Neurons function in the central nervous system by generating signals from synapses, and this only works in the proper chemical environment. An electrical signal is mediated by the sodium channels and leaky potassium channels in which intracellular K ion concentration is higher than its corresponding extracellular concentration, whereas extracellular concentrations of Na, Ca, and Cl ions are higher than
Consciousness and the Brain of patterns in sounds. Dehaene explores consciousness in human babies, non-human animals, and machines. Dehaene reviews evidence that young infants are indeed conscious, although their global workspaces may run 3-4 times slower than in adults, perhaps because their myelin is not well established. Monkeys can be trained to "report" on their conscious experiences via actions rather than speech, and monkeys show the same sorts of brain and behavioral patterns as humans in response to consciousness tests. Dehaene adds that some animals, like monkeys and dolphins, show evidence not just of consciousness but also of metacognition. He speculates that maybe what