Metastability in the brain for a continuum of integration. One theory used to integrate the dynamic core with conscious thought involves a developing concept known as neural Darwinism. In this model, metastable interactions in the thalamocortical region cause a process of selectionism through re-entry (a phenomenon describing the overall reciprocity and interactivity between signals in distant parts of the brain through coupled signal latency). Neuronal selectivity involves mechanochemical events that take place pre- and post-natally whereby neuronal connections are influenced by environmental experiences. The modification of synaptic signals as it relates to the dynamic core provides further explanation for the DCH. Despite growing evidence
Induced stem cells applied to a large number of cells to produce stem cells for medical purposes on an industrial scale. Cells involved in the reprogramming process change morphologically as the process proceeds. This results in physical difference in adhesive forces among cells. Substantial differences in 'adhesive signature' between pluripotent stem cells, partially reprogrammed cells, differentiated progeny and somatic cells allowed to develop separation process for isolation of pluripotent stem cells in microfluidic devices, which is: Stem cells possess mechanical memory (they remember past physical signals) – with the Hippo signaling pathway factors: Yes-associated protein (YAP) and transcriptional coactivator with PDZ-binding domain (TAZ)