Mechanism of anoxic depolarization in the brain intracellular Na and Ca ions, and extracellular glutamate and aspartate. Glutamate and aspartate are normally present as the brain's primary excitatory neurotransmitters, but high concentrations activate a number of downstream apoptotic and necrotic pathways. This results in neuronal dysfunction and death. Neurons function in the central nervous system by generating signals from synapses, and this only works in the proper chemical environment. An electrical signal is mediated by the sodium channels and leaky potassium channels in which intracellular K ion concentration is higher than its corresponding extracellular concentration, whereas extracellular concentrations of Na, Ca, and Cl ions are higher than
Brain Electrical Oscillation Signature Profiling information associated with a prior experience. Brain Electrical Oscillation Signature Profiling Brain Electrical Oscillation Signature Profiling (BEOSP or BEOS) is a technique by which a suspect's participation in a crime is detected by eliciting electrophysiological impulses. It is a non-invasive, scientific technique with a great degree of sensitivity and a neuro-psychological method of interrogation which is sometimes also referred to as ‘brain fingerprinting’. The methodology was developed by Champadi Raman Mukundan (C. R. Mukundan), a Neuroscientist, former Professor & Head of Clinical Psychology at the National Institute of Mental Health and Neurosciences (Bangalore, India), while he worked as a Research