Autoclave Charles Chamberland in 1884, although a precursor known as the steam digester was created by Denis Papin in 1679. The name comes from Greek "auto-", ultimately meaning self, and Latin "clavis" meaning key, thus a self-locking device. Sterilization autoclaves are widely used in microbiology, medicine, podiatry, tattooing, body piercing, veterinary medicine, mycology, funerary practice, dentistry, and prosthetics fabrication. They vary in size and function depending on the media to be sterilized and are sometimes called retort in the chemical and food industries. Typical loads include laboratory glassware, other equipment and waste, surgical instruments, and medical waste. A notable recent and
Sterilization (microbiology) must be sterile. Examples of such instruments include scalpels, hypodermic needles, and artificial pacemakers. This is also essential in the manufacture of parenteral pharmaceuticals. Preparation of injectable medications and intravenous solutions for fluid replacement therapy requires not only sterility but also well-designed containers to prevent entry of adventitious agents after initial product sterilization. Most medical and surgical devices used in healthcare facilities are made of materials that are able to go under steam sterilization. However, since 1950, there has been an increase in medical devices and instruments made of materials (e.g., plastics) that require low-temperature sterilization. Ethylene oxide gas has