Cardiac pacemaker heart. There are 3 main stages in the generation of an action potential in a pacemaker cell. Since the stages are analogous to contraction of cardiac muscle cells, they have the same naming system. This can lead to some confusion. There is no phase 1 or 2, just phases 0, 3, and 4. The key to the rhythmic firing of pacemaker cells is that, unlike other neurons in the body, these cells will slowly depolarize by themselves and do not need any outside innervation from the autonomic nervous system to fire action potentials. As in all other cells, the resting
Heart rate turbulence Heart rate turbulence Heart rate turbulence (HRT) is the return to equilibrium of heart rate after a premature ventricular contraction (PVC). It consists of a brief speed-up in heart rate, followed by a slow decrease back to the baseline rate. An important feature of HRT is that PVCs occur naturally in most adults, so measuring the characteristics of a given person's HRT offers a noninvasive way to evaluate his or her cardiac function without applying artificial external stimuli. The measured values of HRT parameters have been shown to be a statistically significant predictor of the probability of dying from cardiac