Serpula lacrymans 2016). The genus "Serpula", including "S. lacrymans" and "S. himantoides", is known to produce three classes of chemical compounds: pulvinic acid-type family, himanimides, and polyine acids. Within the pulvinic acid-type family, atromentin-derived compounds include variegatic acid, xerocomic acid, isoxerocomic acid, atromentic acid, variegatorubin, xerocomorubin, and other variants of these pigments. Pulvinic acid-type family pigments were found to be secreted during co-incubation with various bacteria. Serpula lacrymans Serpula lacrymans is one of the fungi that cause damage to timber referred to as dry rot. It is a basidiomycete in the order Boletales. The species was first described under the name "Boletus
Atromentin 4-HPP to observe the formation of atromentin. This was followed by characterization of the enzyme GreA in "Suillus grevillei", six (InvA1-6, of which InvA1, 2 and 5 were functional) in "Paxillus involutus", and NPS3 from "Serpula lacrymans". In addition, there is another adjacent and conserved gene encoding for an alcohol dehydrogenase/oxidoreductase whose function is unclear. In most cases the clustered biosynthetic genes are found orthologous in basidiomycetes. A common promoter motif was found shared between the atromentin synthetase and aminotransferase of 23 different atromentin-producing basidiomycetes that was in almost all cases absent from the alcohol dehydrogenase, indicating co-regulation of the