Scoliosis polymorphisms in the "MATN1" gene (encoding for matrilin 1, cartilage matrix protein). Fifty-three single nucleotide polymorphism markers in the DNA that are significantly associated with adolescent idiopathic scoliosis were identified through a genome-wide association study. Adolescent idiopathic scoliosis has no clear causal agent, and is generally believed to be multifactorial. The prevalence of scoliosis is 1% to 2% among adolescents, but the likelihood of progression among adolescents with a Cobb angle less than 20° is about 10% to 20%. Congenital scoliosis can be attributed to a malformation of the spine during weeks three to six "in utero" due to a
The Gifts of the Body the patients and the caregiver. The book contains ten short stories, the titles of each being associated with "gifts" which are various functions of the body, both physical and emotional: sweat, wholeness, tears, skin, hunger, mobility, death, speech, sight, hope, and mourning. The caregiver experiences each "gift", as he/she deals with patients who have AIDS, showing the different shared relationships in each case. Each patient is a distinct case, differing in terms of age, financial situation, attitude toward the illness etc., showing the reader that this disease affects all types of people. The book is written in the "no-frills style"