Mechanism of anoxic depolarization in the brain intracellular Na and Ca ions, and extracellular glutamate and aspartate. Glutamate and aspartate are normally present as the brain's primary excitatory neurotransmitters, but high concentrations activate a number of downstream apoptotic and necrotic pathways. This results in neuronal dysfunction and death. Neurons function in the central nervous system by generating signals from synapses, and this only works in the proper chemical environment. An electrical signal is mediated by the sodium channels and leaky potassium channels in which intracellular K ion concentration is higher than its corresponding extracellular concentration, whereas extracellular concentrations of Na, Ca, and Cl ions are higher than
The Boston process approach the outcomes to make conclusions on what is going on in the brain. These conclusions are based on the errors that occurred during the test. The point of looking at the errors is to see what issues may have occurred when trying to process the information and answer the question in order to evaluate the specific deficit(s). Certain inaccuracies may infer that there’s damage to a definite part of the brain, like speech difficulties implicating the speech area in the left hemisphere. The qualitative analysis focuses on closely observing the process by which a patient arrives at a final answer.