Development of the nervous system in humans in the lower part. Neuronal migration is the method by which neurons travel from their origin or birthplace to their final position in the brain. There most common means of migration are radial and tangential migration. Neuronal precursor cells proliferate in the ventricular zone of the developing neocortex. The first postmitotic cells to migrate from the preplate which are destined to become Cajal-Retzius cells and subplate neurons. These cells do so by somal translocation. Neurons migrating with this mode of locomotion are bipolar and attach the leading edge of the process to the pia. The soma is then transported to
Electrical brain stimulation motor and sensory territories). EBS remains inextricably entwined with the work of Dr. Robert Galbraith Heath, Dr. Jose Delgado and Dr. Wilder Penfield. It's of interest that during cerebral localization studies, neurosurgeon Penfield could not elicit emotional reactions in humans, either by observing spontaneous epilepsy or by electrically stimulating the surface of the cerebral cortex. Neurophysiologist Dr. Jose Delgado noted a few exceptions to this rule. In contrast, EBS, via deeply implanted electrodes in localized areas of the brain (deep brain stimulation; DBS), elicited both pleasurable and aversive responses in laboratory animals and man as previously described. EBS could elicit