Head direction cells efference copy") preparing the network for an impending head turn. HD cells continue to fire in an organized manner during sleep, as if animals were awake. However, instead of always pointing toward the same direction—the animals are asleep and thus immobile—the neuronal "compass needle" moves constantly. In particular, during rapid eye movement sleep, a brain state rich in dreaming activity in humans and whose electrical activity is virtually indistinguishable from the waking brain, this directional signal moves as if the animal is awake: that is, HD neurons are sequentially activated, and the individual neurons representing a common direction during wake
Pinky and the Brain mice are foiled by trying to speak "New York cabbie" and end up going in circles, the gag credit word was "anophelosis" defined as "morbid state due to extreme frustration". Another common element in nearly each episode is the following exchange (often referred to by the acronym "AYPWIP"): Brain: Pinky, are you pondering what I'm pondering?Pinky: I think so, Brain, but... Pinky's response ends with a non-sequitur such as, "we're already naked", "isn't a cucumber that small called a gherkin?" or "if they called them sad meals, kids wouldn't buy them." Brain would then become furious, often bashing Pinky over