Dead Brain Cells the name Dead Brain Cells among three suggestions by Leone, the others being "The Mental Pukes" and "The Retarded Assholes". Lowe had made commitments to his job and could not sing with the band anymore. Dakin decided he would sing and play bass at the same time. The band released two albums and toured twice in the United States. Their first album, "Dead Brain Cells", was released in 1987. It was followed by a concept album, "Universe", in 1989. Their song, "The Genesis Explosion", was featured in a Canadian television commercial for Microcell Telecommunications in 2005. The commercial depicts an
Nanoparticles for drug delivery to the brain drug. Bolaamphiphile nano-vesicles can cross the BBB, and they allow controlled release of the drug to target sites. Lipoplexes can also be formed from cationic liposomes and DNA solutions, to yield transfection agents. Cationic liposomes cross the BBB through adsorption mediated endocytosis followed by internalization in the endosomes of the endothelial cells. By transfection of endothelial cells through the use of lipoplexes, physical alterations in the cells could be made. These physical changes could potentially improve how some nanoparticle drug-carriers cross the BBB. Metal nanoparticles are promising as carriers for drug delivery to the brain. Common metals used for nanoparticle