Radial glial cell the onset of gliogenesis, it is unclear whether they are involved in spinal cord neurogenesis or migration. Radial glia have also been implicated in forming boundaries between different axonal tracts and white matter areas of the brain. As radial glia serve as the primary neural and glial progenitors in the brain, as well as being crucial for proper neuronal migration, defects in radial glial function can have profound effects in the development of the nervous system. Mutations in either Lis1 or Nde1, essential proteins for radial glial differentiation and stabilization, cause the associated neurodevelopmental diseases Lissencephaly and micro-lissencephaly (which literally
Glial scar the spinal cord lesion and this decrease was associated with a reduction in glial scarring. Chondroitinase ABC has been shown to degrade glial scars. Degrading the glial scar with chondroitinase has been shown to promote recovery from spinal cord injury, especially when combined with other techniques such as nerve guidance conduits, schwann cell transplants, and peripheral nerve autografts. Glial scar Glial scar formation (gliosis) is a reactive cellular process involving astrogliosis that occurs after injury to the central nervous system. As with scarring in other organs and tissues, the glial scar is the body's mechanism to protect and begin the