Demographic history of Japan before the Meiji Restoration papers of the Shōsōin (8th century) and others, as well as remnants of specific periods. Since Kyōto (or Heian-kyō) became the capital of Japan in 794, it has been one of the most important cities in Japan. Hiraizumi and Kamakura flourished under Northern Fujiwara clans (during 12th century) and Kamakura shogunate (1192 to 1333), respectively. The urban area of Kyōto suffered from the Ōnin War (1467 to 1477) and split into two districts, but coalesced into a great city of more than 400,000 inhabitants after the end of Sengoku period. The Christian missionaries led by Francis Xavier reported that the
Climate change, industry and society entirely consistent. The spatial distribution, intensity of transmission, and seasonality of malaria is influenced by climate in Sub-saharan Africa. Rainfall can be a limiting factor for mosquito populations and there is some evidence of reductions in transmission associated with decadal decreases in rainfall. The effects of observed climate change on the geographical distribution of malaria and its transmission intensity in highland regions remains controversial. There is no clear evidence that malaria has been affected by climate change in South America or in continental regions of the Russian Federation. There is still much uncertainty about the potential impact of climate change