Nuclear magnetic resonance of anti-parallel spin neutrons (of total spin zero for the neutron-spin pair), plus a proton of spin . Therefore, the tritium total nuclear spin value is again , just like for the simpler, abundant hydrogen isotope, H nucleus (the "proton"). The NMR absorption frequency for tritium is also similar to that of H. In many other cases of "non-radioactive" nuclei, the overall spin is also non-zero. For example, the nucleus has an overall spin value . A non-zero spin formula_2 is always associated with a non-zero magnetic dipole moment, formula_3, via the relation formula_4 where "γ" is the gyromagnetic ratio.
Kinetic isotope effect now relatively routine. Moreover, several qualitative and semi-quantitative models allow rough estimates of deuterium isotope effects to be made without calculations, often providing enough information to rationalize experimental data or even support or refute different mechanistic possibilities. Starting materials containing deuterium are often commercially available, making the synthesis of isotopically enriched starting materials relatively straightforward. Also, due to the large relative difference in the mass of deuterium and protium and the attendant differences in vibrational frequencies, the magnitude of the isotope effect is larger than any other pair of isotopes except protium and tritium, allowing both primary and secondary isotope