Kinetic isotope effect both results are large enough to be indicative of weakening of the C-N bond in the transition state that would occur in a concerted process. Since kinetic isotope effects arise from differences in isotopic masses, the largest observable kinetic isotope effects are associated with isotopic substitutions of hydrogen with deuterium (100% increase in mass) or tritium (200% increase in mass). Kinetic isotope effects from isotopic mass ratios can be as large as 36.4 using muons. They have produced the lightest hydrogen atom, H (0.113 amu), in which an electron orbits around a positive muon (μ) "nucleus" that has a mass
Tritium 65 nuclear sites in the US. In one case, leaking water contained of tritium per litre, which is 375 times the EPA limit for drinking water. The US Nuclear Regulatory Commission states that in normal operation in 2003, 56 pressurized water reactors released of tritium (maximum: 2,080 Ci; minimum: 0.1 Ci; average: 725 Ci) and 24 boiling water reactors released (maximum: 174 Ci; minimum: 0 Ci; average: 27.7 Ci), in liquid effluents. According to the U.S. Environmental Protection Agency, self-illuminating exit signs improperly disposed in municipal landfills have been recently found out to contaminate waterways. The legal limits for tritium