History of neuroscience that the functional unit of the brain is the neuron. Golgi and Ramón y Cajal shared the Nobel Prize in Physiology or Medicine in 1906 for their extensive observations, descriptions and categorizations of neurons throughout the brain. The hypotheses of the neuron doctrine were supported by experiments following Galvani's pioneering work in the electrical excitability of muscles and neurons. In the late 19th century, Emil du Bois-Reymond, Johannes Peter Müller, and Hermann von Helmholtz showed neurons were electrically excitable and that their activity predictably affected the electrical state of adjacent neurons. In parallel with this research, work with brain-damaged patients
Signals, Crane and Subway, Charters Towers railway station mechanical signals were controlled from signal cabins, which dealt with the traffic on a particular block of railway line. Signal cabins coordinated signals that indicated whether or not a section of track was clear of other traffic. Early signals were mechanical, while later signals were operated electrically. The most common form of mechanical signal was the semaphore signal. These consisted of a metal framed tower with one or more arms that could be inclined at different angles, with the arm at the horizontal signalling "danger", or do not proceed. Mechanical signals were usually worked by a wire cable running from