Helium-3 of the airway tree, locate unventilated defects, measure the alveolar oxygen partial pressure, and measure the ventilation/perfusion ratio. This technique may be critical for the diagnosis and treatment management of chronic respiratory diseases such as chronic obstructive pulmonary disease (COPD), emphysema, cystic fibrosis, and asthma. Production, sales and distribution of helium-3 in the United States are managed by the US Department of Energy (DOE) Isotope Program. Virtually all helium-3 used in industry today is produced from the radioactive decay of tritium. Tritium is a radioactive isotope of hydrogen and is typically produced by bombarding lithium-6 with neutrons in a nuclear
Atomic vapor laser isotope separation Atomic vapor laser isotope separation Atomic vapor laser isotope separation, or AVLIS, is a method by which specially tuned lasers are used to separate isotopes of uranium using selective ionization of hyperfine transitions. As compared to gas centrifuges the AVLIS process provides high energy efficiency, high separation factors, and a low volume of radioactive waste. A similar technology, using molecules instead of atoms, is molecular laser isotope separation (MLIS). The absorption lines of and U differ slightly due to hyperfine structure; for example, the U absorption peak of 502.74 nanometers shifts to 502.73 nm in U. AVLIS uses tunable dye