Glial scar brain and spinal cord. FGF2 has also been shown to increase astrocyte proliferation "in vitro". Ciliary neurotrophic factor (CNTF) is a cytosolic protein that is not secreted. CNTF has been shown to promote the survival of neuronal cultures "in vitro", and it can also act as a differentiator and trophic factor on glial cells. Further, CNTF has been previously shown to affect the differentiation of glial precursor cells "in vitro"; however, the influence of CNTF in the "in vivo" setting has only recently been determined. Winter "et al." used CNTF over-expressing transgenic mice as well as wildtype controls that had
Human body as multicellular organisms which reside in the gastrointestinal tract and on the skin. Not all parts of the body are made from cells. Cells sit in an extracellular matrix that consists of proteins such as collagen, surrounded by extracellular fluids. Of the 70 kg weight of an average human body, nearly 25 kg is non-human cells or non-cellular material such as bone and connective tissue. Cells in the body function because of DNA. DNA sits within the nucleus of a cell. Here, parts of DNA are copied and sent to the body of the cell via RNA. The RNA is