Dry rot be more distinctive in these species than water translocation. Water translocated in this fashion carries nutrients to the extremities of the organism; not, as is sometimes inferred, to simply render dry timber wet enough to attack. Coggins goes into more detail about water movement in "Serpula lacrymans". The perpetual saturation of wood with water also inhibits dry rot, as does perpetual dryness. "Dry rot" would appear to be a paradoxical term seemingly indicating decay of a substance by a fungus without the presence of water. However, its historical usage dates back to the distinction between decay of cured wood in
Serpula lacrymans of 13805 genes. "S. lacrymans"' genome encodes six annotated polyketide synthases (PKS1-PKS6), 15 nonribosomal peptide synthetases (NPS1-NPS4, NPS7, NPS13-NPS15, NPS17, and NPS18), and two hybrids thereof (NPS6, NPS8, and NPS16). Additionally, the genome encodes for various putative adenylate-forming reductases (NPS5, NPS9-NPS12) (Eastwood et al., 2011). "NPS3" was overexpressed in E. coli and characterized as an atromentin/quinone synthetase that catalyzes the formation of atromentin, similar to GreA; InvA1,2 and 5; and AtrA from Suillus grevillei, Tapinella panuoides, Paxillus involutus, respectively. "NPS3" and its adjacent clustered aminotransferase gene ("AMT1") were also found to be up-regulated during co-incubation with bacteria (Tauber et al.,