Big Bang nucleosynthesis amounts of the hydrogen isotope deuterium (H or D), the helium isotope helium-3 (He), and a very small amount of the lithium isotope lithium-7 (Li). In addition to these stable nuclei, two unstable or radioactive isotopes were also produced: the heavy hydrogen isotope tritium (H or T); and the beryllium isotope beryllium-7 (Be); but these unstable isotopes later decayed into He and Li, as above. Essentially all of the elements that are heavier than lithium were created much later, by stellar nucleosynthesis in evolving and exploding stars. There are several important characteristics of Big Bang nucleosynthesis (BBN): The key parameter
Isotope dilution employed with mass spectrometry in applications where high-accuracy is demanded. For example, all National Metrology Institutes rely significantly on isotope dilution when producing certified reference materials. In addition to high-precision analysis, isotope dilution is applied when low recovery of the analyte is encountered. In addition to the use of stable isotopes, radioactive isotopes can be employed in isotope dilution which is often encountered in biomedical applications, for example, in estimating the volume of blood. Consider a natural analyte rich in isotope A (denoted as A), and the same analyte, enriched in isotope A (denoted as B). Then, the obtained mixture