Scoliosis and Spinal Disorders from the Department of Orthopaedics and Traumatology, The University of Hong Kong in Hong Kong. Scoliosis and Spinal Disorders Scoliosis and Spinal Disorders () is an international, multidisciplinary open-access, peer-reviewed, online-only medical journal addressing all spine conditions. The journal encompasses all aspects of research on prevention, diagnosis, treatment, outcomes and cost-analyses of conservative and surgical management of all spinal deformities, disorders and conditions (e.g. low back pain, degenerative disc disease, trauma, etc). Both clinical and basic science reports form the cornerstone of the journal in its endeavor to provide original, primary studies as well as narrative/systematic reviews and meta-analyses to
Scoliosis is due to genetic factors, and 62% is due to the environment. The genetics are likely complex, however, given the inconsistent inheritance and discordance among monozygotic twins. The specific genes that contribute to development of scoliosis have not been conclusively identified. At least one gene, "CHD7", has been associated with the idiopathic form of scoliosis. Several candidate gene studies have found associations between idiopathic scoliosis and genes mediating bone formation, bone metabolism, and connective tissue structure. Several genome-wide studies have identified a number of loci as significantly linked to idiopathic scoliosis. In 2006, idiopathic scoliosis was linked with three microsatellite