Management of scoliosis two children to reach 24 month follow-up (aged 5 and 12 years) is encouraging. Monthly rod lengthening produced a progressive increase in spinal length and correction of scoliosis was maintained. Although these methods are novel and promising, they are suitable only for growing patients with early-onset scoliosis, and have a high complication rate. Spinal fusion remains the "gold standard" of surgical treatment for scoliosis. The risk of undergoing surgery for scoliosis was estimated in 2008 to be varying, but with a high rate of complications. Possible complications may be inflammation of the soft tissue or deep inflammatory processes, breathing impairments,
Scoliosis is due to genetic factors, and 62% is due to the environment. The genetics are likely complex, however, given the inconsistent inheritance and discordance among monozygotic twins. The specific genes that contribute to development of scoliosis have not been conclusively identified. At least one gene, "CHD7", has been associated with the idiopathic form of scoliosis. Several candidate gene studies have found associations between idiopathic scoliosis and genes mediating bone formation, bone metabolism, and connective tissue structure. Several genome-wide studies have identified a number of loci as significantly linked to idiopathic scoliosis. In 2006, idiopathic scoliosis was linked with three microsatellite