History of neuroscience that the functional unit of the brain is the neuron. Golgi and Ramón y Cajal shared the Nobel Prize in Physiology or Medicine in 1906 for their extensive observations, descriptions and categorizations of neurons throughout the brain. The hypotheses of the neuron doctrine were supported by experiments following Galvani's pioneering work in the electrical excitability of muscles and neurons. In the late 19th century, Emil du Bois-Reymond, Johannes Peter Müller, and Hermann von Helmholtz showed neurons were electrically excitable and that their activity predictably affected the electrical state of adjacent neurons. In parallel with this research, work with brain-damaged patients
Process tomography imaging methods are used in process tomography, e.g. ultrasonic imaging, positron emission tomography (PET), electrical resistance tomography (ERT) and electrical impedance tomography (EIT), electrical capacitance tomography (ECT), magnetic induction tomography (MIT). In all cases external sensors are used to detect signals from boundary of the object, and the three-dimensional material distribution or the velocity field is computed using the measured data. Process tomography is an area of rapid growth both in terms of research and applications. There are number of challenges remaining in this area including data processing an image reconstruction, and application of imaging modalities in a real applications.