Radial glial cell the onset of gliogenesis, it is unclear whether they are involved in spinal cord neurogenesis or migration. Radial glia have also been implicated in forming boundaries between different axonal tracts and white matter areas of the brain. As radial glia serve as the primary neural and glial progenitors in the brain, as well as being crucial for proper neuronal migration, defects in radial glial function can have profound effects in the development of the nervous system. Mutations in either Lis1 or Nde1, essential proteins for radial glial differentiation and stabilization, cause the associated neurodevelopmental diseases Lissencephaly and micro-lissencephaly (which literally
Amniotic stem cells confirmed as mesenchymal stem cells were obtained. In addition, evidence indicated that embryonic stem cells are part of the fluid, although in very small quantities. At around the same time, it was determined that stem cells from the amniotic membrane also have multipotent potential. AS their differentiation into neural and glial cells as well as hepatocyte precursors was observed. The majority of stem cells present in the amniotic fluid share many characteristics, which suggests they may have a common origin. In 2007, it was confirmed that the amniotic fluid contains a heterogeneous mixture of multipotent cells after it was demonstrated