Coal tar can be injurious to health. Coal tar is also used to manufacture paints, synthetic dyes (notably tartrazine/Yellow #5), and photographic materials. In the coal gas era, there were many companies in Britain whose business was to distill coal tar to separate the higher-value fractions, such as naphtha, creosote and pitch. A great many industrial chemicals were first isolated from coal tar during this time. These companies included: Side effects of coal tar products include skin irritation, sun sensitivity, allergic reactions, and skin discoloration. It is unclear if use during pregnancy is safe for the baby and use during breastfeeding is
Picoline its unpleasant smell. In 1849, the Scottish chemist Thomas Anderson (1819 – 1874) prepared picoline in pure form, from coal tar and via the pyrolysis of bones. Anderson also named picoline by combining the Latin words "pix" (tar) and "oleum" (oil) because coal tar oil was a source of picoline. By 1870, the German chemist Adolf von Baeyer had synthesized picoline in two ways: by the dry distillation of "acroleïnammoniak" (CH=CH-CH=N-CHOH-CH=CH) and by heating "tribromallyl" (1,2,3-tribromopropane) with ammonia in ethanol. In 1871, the English chemist and physicist James Dewar speculated that picoline was methylpyridine. If the structure of pyridine that