Gliadin intolerance of wheat, barley and rye – all of which contain prolamins. Gliadin proteins have the ability to provoke an autoimmune enteropathy caused by an abnormal immune response in genetically susceptible individuals. Specific amino acid sequences within the gliadin proteins are responsible for this activity. The main problems with this disease is that it often goes unrecognized for many years, in which it can cause serious damage to several organs, and most cases currently remain unrecognized, undiagnosed and untreated. Mainly intestinal villi destruction mediated by Interferon Gamma and CD 4(+). Celiac disease with "non-classic symptoms" is the most common clinical
Storage protein of the dry weight of the seed can be composed of storage proteins. The best known storage protein in wheat is the prolamin gliadin, a component of gluten. Storage protein Storage proteins serve as biological reserves of metal ions and amino acids, used by organisms. They are found in plant seeds, egg whites, and milk. Ferritin is an example of a storage protein that stores iron. Iron is a component of heme, which is contained in the transport protein, hemoglobin and in cytochromes. Some storage proteins store amino acids. Storage proteins' amino acids are used in embryonic development of animals