Hypha Hypha A hypha (plural hyphae, from Greek ὑφή, "huphḗ", "web") is a long, branching filamentous structure of a fungus, oomycete, or actinobacterium. In most fungi, hyphae are the main mode of vegetative growth, and are collectively called a mycelium. A hypha consists of one or more cells surrounded by a tubular cell wall. In most fungi, hyphae are divided into cells by internal cross-walls called "septa" (singular septum). Septa are usually perforated by pores large enough for ribosomes, mitochondria and sometimes nuclei to flow between cells. The major structural polymer in fungal cell walls is typically chitin, in contrast to
Industrial fermentation of glucose or other carbon sources which would encourage growth, and like primary metabolites are released into the surrounding medium without rupture of the cell membrane. In the early days of the biotechnology industry, most biopharmaceutical products were made in "E. coli"; by 2004 more biopharmaceuticals were manufactured in eukaryotic cells, like CHO cells, than in microbes, but used similar bioreactor systems. Insect cell culture systems came into use in the 2000s as well. Of primary interest among the intracellular components are microbial enzymes: catalase, amylase, protease, pectinase, glucose isomerase, cellulase, hemicellulase, lipase, lactase, streptokinase and many others. Recombinant proteins,