Radial glial cell and OPCs can be generated from radial glial cells "in vitro", more evidence is yet needed to conclude whether this process also occurs in the developing brain. Recently, radial glia that exclusively generate upper-layer cortical neurons have also been discovered. Since upper cortical layers have expanded greatly in recent evolution, and are associated with higher-level information processing and thinking, radial glia have been implicated as important mediators of brain evolution. The best characterized and first widely accepted function of radial glia is their role as scaffolds for neuronal migration in the cerebral and cerebellar cortexes. This role can be easily
Amniotic stem cells confirmed as mesenchymal stem cells were obtained. In addition, evidence indicated that embryonic stem cells are part of the fluid, although in very small quantities. At around the same time, it was determined that stem cells from the amniotic membrane also have multipotent potential. AS their differentiation into neural and glial cells as well as hepatocyte precursors was observed. The majority of stem cells present in the amniotic fluid share many characteristics, which suggests they may have a common origin. In 2007, it was confirmed that the amniotic fluid contains a heterogeneous mixture of multipotent cells after it was demonstrated