James Bayley Butler with the Royal Army Medical Corps, beginning as a lieutenant in 1915 and retiring a major after the war. For his service, he was awarded an MBE. Butler's primary research interest was in applied biology. He carried out research on "Catenaria anguillulae", a parasite of the ova of the liver fluke, from 1922 to 1932. Later on, Butler focused on the control of wood-boring beetles and the fungus that causes dry rot in wood "Serpula lacrymans". On this matter, he became an international expert, and assisted in the development of the company Biotox, which manufactured insecticides and fungicides for use
Serpula himantioides appear as distinctive fruiting bodies on the exterior of the host. "S. himantioides" prefers the moist wood of coniferous hosts such as fir, larch, spruce, and pine. It is the causal agent of butt rot disease, the symptoms of which include rotting the heartwood at base of tree, as well as damage to the tap root and cores of lateral roots, but standing trees show no signs of infection. It also a common cause of timber rotting in buildings, which has made this pathogen difficult to differentiate from "S. lacrymans" because of their similarities. This disease often goes unnoticed initially