Serpula lacrymans dry rot was at least 150 million pounds per annum. Three variants/strains of S. lacrymans have been sequenced by the Joint Genome Institute (JGI) and its collaborators, and sequence data is available via their MycoCosm portal. One genome is from Serpula lacrymans S7.9 (v2.0). The genome assembly is 42.73 Mbp, with a predicted number of 12789 genes. The second genome is from Serpula lacrymans S7.3 (v2.0). The genome assembly is 47 Mbp, with a predicted number of 14495 genes. The third genome is from Serpula lacrymans var shastensis SHA21-2 (v1.0). The genome assembly is 45.98 Mbp, with a predicted number
Serpula himantioides appear as distinctive fruiting bodies on the exterior of the host. "S. himantioides" prefers the moist wood of coniferous hosts such as fir, larch, spruce, and pine. It is the causal agent of butt rot disease, the symptoms of which include rotting the heartwood at base of tree, as well as damage to the tap root and cores of lateral roots, but standing trees show no signs of infection. It also a common cause of timber rotting in buildings, which has made this pathogen difficult to differentiate from "S. lacrymans" because of their similarities. This disease often goes unnoticed initially