Glucose are termed glucans. Glucose is produced by plants through the photosynthesis using sunlight, water and carbon dioxide and can be used by all living organisms as an energy and carbon source. However, most glucose does not occur in its free form, but in the form of its polymers, i.e. lactose, sucrose, starch and others which are energy reserve substances, and cellulose and chitin, which are components of the cell wall in plants or fungi and arthropods, respectively. These polymers are degraded to glucose during food intake by animals, fungi and bacteria using enzymes. All animals are also able to produce
Glucose-6-phosphate translocase potential for G6PT1 but systematically lack specificity in inhibition, rendering them poor drug candidates. Since the late 1990s, natural products have been increasingly studied as potent and specific inhibitors of G6PT1. Prominent examples of natural inhibitors include mumbaistatin and analogs, kodaistatin (harvested from extracts of "Asperigillus terreus") and chlorogenic acid. Other natural product inhibitors of G6PT1 are found in the fungi "Chaetomium carinthiacum", "Bauhinia magalandra" leaves, and streptomyces bacteria. 1) Excessive activity of G6PT1 may contribute to the development of diabetes. Diabetes mellitus type 2 is a disease characterized by chronically elevated blood glucose levels, even when fasting. The rapidly