Oryza sativa dating from 12,000–11,000 BP indicates that wild rice collection was part of the local means of subsistence. Changes in the morphology of Diaotonghuan phytoliths dating from 10,000–8,000 BP show that rice had by this time been domesticated. Analysis of Chinese rice residues from Pengtoushan, which were carbon 14 dated to 8200–7800 BC, show that rice had been domesticated by this time. In 1998, Crawford and Shen reported the earliest of 14 AMS or radiocarbon dates on rice from at least nine Early to Middle Neolithic sites are no older than 7000 BC, that rice from the Hemudu and Luojiajiao sites
12-oxophytodienoate reductase 12-oxophytodienoate reductase 12-oxophytodienoate reductase (OPRs) is an enzyme of the family of Old Yellow Enzymes (OYE). OPRs are grouped into two groups: OPRI and OPRII – the second group is the focus of this article, as the function of the first group is unknown, but is the subject of current research. The OPR enzyme utilizes the cofactor flavin mononucleotide (FMN) and catalyzes the following reaction in the jasmonic acid synthesis pathway: This reaction occurs in peroxisomes in plants. Several isozymes have been discovered, with varying substrate stereospecificity: three in "Lycopersicon esculentum", 13 in "Oryza sativa", and five in "Arabidopsis thaliana".