Human brain the largest cells (by size of cell body) in the nervous system. The adult human brain is estimated to contain 86±8 billion neurons, with a roughly equal number (85±10 billion) of non-neuronal cells. Out of these neurons, 16 billion (19%) are located in the cerebral cortex, and 69 billion (80%) are in the cerebellum. Types of glial cell are astrocytes (including Bergmann glia), oligodendrocytes, ependymal cells (including tanycytes), radial glial cells and microglia. Astrocytes are the largest of the glial cells. They are stellate cells with many processes radiating from their cell bodies. Some of these processes end as perivascular
Radial glial cell astrocytes, they have also been called "specialized astrocytes." Bergmann glia have multiple radial processes that extend across the molecular layer of the cerebral cortex and terminate at the pial surface as a bulbous endfoot. Bergmann glial cells assist with the migration of granule cells, guiding the small neurons from the external granular layer to the internal granular layer of the cerebral cortex along their extensive radial processes. Besides their role in early development of the cerebellum, Bergmann glia are also required for synaptic pruning. Following Purkinje cell death induced by CNS injury, Bergmann glia undergo extensive proliferative changes so as