Gluten immunochemistry to react with gamma gliadin to a degree comparable to DQ2.5. T-cell responses to the high molecular weight glutenin may be more important with DQ8 mediated than DQ2.5 mediated celiac disease. Antibody recognition of gluten is complex. Direct binding to gluten such as anti-gliadin antibodies has an ambiguous pathogenesis in coeliac disease. The crosslinking of gliadin with tissue transglutaminase leads to the production of anti-transglutaminase antibodies, but this is mediated through T-cell recognition of gliadin. The allergic recognition of gliadin by mast cells, eosinophiles in the presence of IgE has notable direct consequences, such as exercise-induced anaphylaxis. Anti-gliadin antibodies, like
Gluten-free, casein-free diet cream topping, which use casein to provide texture. Although advocates of the GFCF diet often recommend total elimination of dairy from the diet, whey protein is a different milk protein from casein. Gluten-free, casein-free diet Gluten-free casein-free diet (GFCF diet), also known as gluten-free dairy-free diet (GFDF diet), is a diet that does not include the proteins gluten (found most often in wheat, barley, and rye), and casein (found most often in milk and dairy products). Despite an absence of scientific evidence, there have been advocates for the use of this diet as a treatment for autism and related conditions.