Endoskeleton three phyla and one subclass of animals, endoskeletons of various complexity are found: Chordata, Echinodermata, Porifera, and Coleoidea. An endoskeleton may function purely for support (as in the case of sponges), but often serves as an attachment site for muscle and a mechanism for transmitting muscular forces. A true endoskeleton is derived from mesodermal tissue. Such a skeleton is present in echinoderms and chordates. The poriferan 'skeleton' consists of microscopic calcareous or siliceous spicules or a spongin network. The Coleoidae do not have a true endoskeleton in the evolutionary sense; there, a mollusk exoskeleton evolved into several sorts of internal
Death Domain database For example, DED will only bind with DED, CARD-CARD, PYD-PYD and DD-DD. These homotypic interactions are with only two members of the same domain (or on rare occasions with more) and there has been no evidence to suggest that these domains have heterotypic interactions with one another. DED domains are highly conserved in the Chordata phylum and can also be found in smaller percentages in the Echinodermata phylum and viruses. DED-containing proteins are associated with apoptosis regulation with caspase protein interaction and have been notably documented in mammals. DED domains have been known to interact with other domains and include: