Kinetic isotope effect both results are large enough to be indicative of weakening of the C-N bond in the transition state that would occur in a concerted process. Since kinetic isotope effects arise from differences in isotopic masses, the largest observable kinetic isotope effects are associated with isotopic substitutions of hydrogen with deuterium (100% increase in mass) or tritium (200% increase in mass). Kinetic isotope effects from isotopic mass ratios can be as large as 36.4 using muons. They have produced the lightest hydrogen atom, H (0.113 amu), in which an electron orbits around a positive muon (μ) "nucleus" that has a mass
Tritium in small quantities by some nuclear power plants. In January 2014 it was made public that a total of 875 TBq (2.45 g) of tritium are on the site of Fukushima Daiichi, and the amount of tritium contained in the contaminated water is increasing by approximately 230 TBq (0.64 g) per year. According to a report by Tepco ""Tritium could be separated theoretically, but there is no practical separation technology on an industrial scale"." Tritium's decay product helium-3 has a very large cross section for reacting with thermal neutrons, expelling a proton, hence it is rapidly converted back to tritium