Pyrolysis oil are affected by temperature, reaction time, algae species, algae concentration, reaction atmosphere, and catalysts, in subcritical water reaction conditions. Bio-oil typically requires significant additional treatment to render it suitable as a refinery feedstock to replace crude oil derived from petroleum, coal-oil, or coal-tar. Tar is a black mixture of hydrocarbons and free carbon obtained from a wide variety of organic materials through destructive distillation. Tar can be produced from coal, wood, petroleum, or peat. Wood-tar creosote is a colourless to yellowish greasy liquid with a smoky odor, produces a sooty flame when burned, and has a burned taste. It is
Coal tar to squamous cell carcinoma. The International Agency for Research on Cancer lists coal tars as Group 1 carcinogens, meaning they directly cause cancer. Both the U.S. Department of Health and Human Services and the state of California list coal tars as known human carcinogens. Coal tar causes increased sensitivity to sunlight, so skin treated with topical coal tar preparations should be protected from sunlight. The residue from the distillation of high-temperature coal tar, primarily a complex mixture of three or more membered condensed ring aromatic hydrocarbons, was listed on 28 October 2008 as a substance of very high concern by