Kinetic Isotope Effects of RuBisCO carbon, oxygen, and/or hydrogen, though currently only a significant isotope effect is seen for carbon isotope substitution. Isotopes are atoms that have the same number of protons but varying numbers of neutrons. "Lighter" isotopes (like the stable Carbon-12 isotope) have a smaller overall mass, and "heavier" isotopes (like the stable Carbon-13 isotope or radioactive Carbon-14 isotope) have a larger overall mass. Stable isotope geochemistry is concerned with how varying chemical and physical processes preferentially enrich or deplete stable isotopes. Enzymes like RuBisCO cause isotopic fractionation because molecules containing lighter isotopes have higher zero-point energies (ZPE), the lowest possible quantum energy
Radioactive Isotope Beam Factory Radioactive Isotope Beam Factory The Radioactive Isotope Beam Factory is a multistage particle accelerator complex operated by Japan's Nishina Center for Accelerator-Based Science which is itself a part of the Institute of Physical and Chemical Research. Located in Saitama, the RIBF generates unstable nuclei of all elements up to uranium and studies their properties. According to physicist Robert Janssens, ""[it] can produce the most intense beams of primary particles in the world."" RIBF took ten years to construct and its Superconducting Ring Cyclotron (SRC) can achieve energies of 2,600 MeV. Work at the RIBF has contributed to the understanding of