Jan F. Esser Jan F. Esser Johannes "Jan" Fredericus Samuel Esser (13 October 1877 in Leiden – 9 August 1946 in Chicago) was a Dutch plastic surgeon who pioneered innovative methods of reconstructive surgery on soldiers wounded in the First World War. He is thought to have coined the term "stent" in 1917 to describe his use of a dental impression compound invented in 1856 by the English dentist Charles Stent (1807–1885) to create a form for facial reconstruction. The term "stent" was later extended to mean a device to expand constricted tubes of body tissue. He was a one time Dutch Chess
Coronary stent tendency for clots to form at the site where the stent damages the arterial wall. Since platelets are involved in the clotting process, patients must take dual antiplatelet therapy starting immediately before or after stenting: usually an ADP receptor antagonist (e.g. clopidogrel or ticagrelor) and aspirin for one year and aspirin indefinitely. In order to reduce the treatment, a new generation of stent has been developed with biodegradable polymer. However, the dual antiplatelet therapy may be insufficient to fully prevent clots that may result in stent thrombosis; these and the cell proliferation may cause the standard (“bare-metal”) stents to become