Native Americans in the United States reached the West Coast in the 1770s, smallpox rapidly killed at least 30% of Northwest Coast Native Americans. For the next eighty to one hundred years, smallpox and other diseases devastated native populations in the region. Puget Sound area populations, once estimated as high as 37,000 people, were reduced to only 9,000 survivors by the time settlers arrived en masse in the mid-19th century. Smallpox epidemics in 1780–82 and 1837–38 brought devastation and drastic depopulation among the Plains Indians. By 1832, the federal government established a smallpox vaccination program for Native Americans ("The Indian Vaccination Act of 1832"). It was
Chinese Americans populations. In addition to the big cities, smaller pockets of Chinese Americans are also dispersed in rural towns, often university-college towns, throughout the United States. For example, the number of Chinese Americans, including college professors, doctors, professionals, and students, has increased over 200% from 2005 to 2010 in Providence, Rhode Island, a small city with a large number of colleges. Income and social status of these Chinese-American locations vary widely. Although many Chinese Americans in Chinatowns of large cities are often members of an impoverished working class, others are well-educated upper-class people living in affluent suburbs. The upper and lower-class