Tree from the cinchona tree ("Cinchona") and was for a long time the remedy of choice for the treatment of malaria. Aspirin was synthesised to replace the sodium salicylate derived from the bark of willow trees ("Salix") which had unpleasant side effects. The anti-cancer drug Paclitaxel is derived from taxol, a substance found in the bark of the Pacific yew ("Taxus brevifolia"). Other tree based drugs come from the paw-paw ("Carica papaya"), the cassia ("Cassia spp."), the cocoa tree ("Theobroma cacao"), the tree of life ("Camptotheca acuminata") and the downy birch ("Betula pubescens"). The papery bark of the white birch tree
Pterocarya fraxinifolia appear in April, the male catkins thick and green, 7.5 – 12.5 cm long, the females longer with less dense flowers, bearing red styles forming fruiting catkins 30 – 50 cm long, the green, winged, nuts approximately 1.8 cm wide. The species is fast growing and grows best on flat ground or shallow slopes near river banks and in deep moist soils. The climate associated with the distribution of this tree includes mild winters and mild humid summers. It generally grows in mixed stands with other species and rarely grows in pure stands. Fossils of "Pterocarya fraxinifolia" have been described