Scoliosis polymorphisms in the "MATN1" gene (encoding for matrilin 1, cartilage matrix protein). Fifty-three single nucleotide polymorphism markers in the DNA that are significantly associated with adolescent idiopathic scoliosis were identified through a genome-wide association study. Adolescent idiopathic scoliosis has no clear causal agent, and is generally believed to be multifactorial. The prevalence of scoliosis is 1% to 2% among adolescents, but the likelihood of progression among adolescents with a Cobb angle less than 20° is about 10% to 20%. Congenital scoliosis can be attributed to a malformation of the spine during weeks three to six "in utero" due to a
Supernumerary body part two or more different populations of genetically distinct cells that originated in different zygotes that have merged; anatomical structures are typically mixed depending on which cells are prevalent in different body parts, for example plants can have two different types of flowers. A mosaic is a genetic anomaly similar in nature and effects to a chimera: genetically different populations of cells within one organism, originated from some propagated mutation of a single cell rather than from outside sources. In Hindu mythology, additional limbs and heads are considered a sign of power. In Greek mythology, Artemis, the goddess of fertility, was