Autoclave Charles Chamberland in 1884, although a precursor known as the steam digester was created by Denis Papin in 1679. The name comes from Greek "auto-", ultimately meaning self, and Latin "clavis" meaning key, thus a self-locking device. Sterilization autoclaves are widely used in microbiology, medicine, podiatry, tattooing, body piercing, veterinary medicine, mycology, funerary practice, dentistry, and prosthetics fabrication. They vary in size and function depending on the media to be sterilized and are sometimes called retort in the chemical and food industries. Typical loads include laboratory glassware, other equipment and waste, surgical instruments, and medical waste. A notable recent and
Sterilization (microbiology) in this case, it is prepared on-site by depolymerization of solid paraformaldehyde. Many vaccines, such as the original Salk polio vaccine, are sterilized with formaldehyde. Hydrogen peroxide, in both liquid and as vaporized hydrogen peroxide (VHP), is another chemical sterilizing agent. Hydrogen peroxide is a strong oxidant, which allows it to destroy a wide range of pathogens. Hydrogen peroxide is used to sterilize heat- or temperature-sensitive articles, such as rigid endoscopes. In medical sterilization, hydrogen peroxide is used at higher concentrations, ranging from around 35% up to 90%. The biggest advantage of hydrogen peroxide as a sterilant is the short