Scoliosis up to $5,000 during rapid growth periods, when braces must be consistently replaced across multiple follow-ups. Since scoliosis was discovered by Hippocrates, physicians and orthopedic surgeons have sought to find a cure for the condition. In the mid-20th century, modern medicine and treatment made decreasing the progression of scoliosis within patients and alleviating the pain they experienced possible. This was the result of the progression of scoliosis screenings and treatment. New ways were developed to treat scoliosis because the condition was increasingly understood among medical professionals and orthopedic surgeons. These treatments such as bracing and rod insertion into the spine
Scoliosis is due to genetic factors, and 62% is due to the environment. The genetics are likely complex, however, given the inconsistent inheritance and discordance among monozygotic twins. The specific genes that contribute to development of scoliosis have not been conclusively identified. At least one gene, "CHD7", has been associated with the idiopathic form of scoliosis. Several candidate gene studies have found associations between idiopathic scoliosis and genes mediating bone formation, bone metabolism, and connective tissue structure. Several genome-wide studies have identified a number of loci as significantly linked to idiopathic scoliosis. In 2006, idiopathic scoliosis was linked with three microsatellite