Chitin crustacean waste and mushrooms for possible development of products in tissue engineering, medicine, and industry. Chitin Chitin (CHON) ( ), a long-chain polymer of "N"-acetylglucosamine, is a derivative of glucose. It is a primary component of cell walls in fungi, the exoskeletons of arthropods, such as crustaceans (e.g., crabs, lobsters and shrimps) and insects, the radulae of molluscs, cephalopod beaks, and the scales of fish and lissamphibians. The structure of chitin is comparable to another polysaccharide - cellulose, forming crystalline nanofibrils or whiskers. In terms of function, it may be compared to the protein keratin. Chitin has proved useful for
Stromal cell-derived factor 1 receptors, of which CXCR stands out, regulate multiple processes such as morphogenesis, angiogenesis, and immune responses and are considered potential targets for drug development. In the gastrointestinal tract system, the CXCL12-CXCR4 axis is under investigation as an anti-fibrotic therapy in the treatment for chronic pancreatitis. For instance, blocking CXCR4, the receptor for CXCL12, with Plerixafor (AMD-3100) increased the effectiveness of combretastatin in a mouse model of breast cancer, presumably by preventing macrophages from being recruited to tumours.[15][16] Stromal cell-derived factor 1 The stromal cell-derived factor 1 (SDF1), also known as C-X-C motif chemokine 12 (CXCL12), is a chemokine protein that