Erythema toxicum neonatorum Erythema toxicum neonatorum Erythema toxicum neonatorum (also known as erythema toxicum, urticaria neonatorum and toxic erythema of the newborn) is a common rash in neonates. It appears in up to half of newborns carried to term, usually between day 2–5 after birth; it does not occur outside the neonatal period. Erythema toxicum is characterized by blotchy red spots on the skin with overlying white or yellow papules or pustules. These lesions may be few or numerous. The eruption typically resolves within first two weeks of life and frequently individual lesions will appear and disappear within minutes or hours. It is
Pruritic urticarial papules and plaques of pregnancy usually also spared and does not seem to become affected. Skin distension (stretching) is a common factor in PUPPP, which is more common in mothers with large fundal measurements and/or those who are carrying large babies, twins, and triplets. The papules and plaques often first appear within stretch marks. Certain studies reveal that this condition is more frequent in women carrying boys, although no formal research has been conducted. Statistics cite that 70% of PUPPP sufferers deliver boys. PUPPP occurs in about 1 in every 200 pregnancies. The cause of the condition is generally unknown. This skin condition occurs mostly