Apamin therapeutic effect on Parkinson's disease. Dopamine, which is depleted in this disease, will be released from midbrain dopaminergic neurons when these SK channels are inhibited. SK channels have also been proposed as targets for the treatment of epilepsy, emotional disorders and schizophrenia. Apamin Apamin is an 18 amino acid peptide neurotoxin found in apitoxin (bee venom). Dry bee venom consists of 2–3% of apamin. Apamin selectively blocks SK channels, a type of Ca-activated K channel expressed in the central nervous system. Toxicity is caused by only a few amino acids, these are cysteine, lysine, arginine, arginine and histidine. These amino
Hennessey Venom GT the car's six year production run and to mark an end to the production of the Venom GT. The engine output is the same but the curb weight has been decreased by . The livery of the car is a "Glacier Blue" paint job with double narrow white stripes. The vehicle was pre-sold for before its public debut. The Hennessey Venom GT is succeeded by the Hennessey Venom F5, which was unveiled in November 2017; unlike its predecessor, it is a series production car built completely from the ground up, including chassis and engine. Hennessey Venom GT The Hennessey Venom