1793 Philadelphia yellow fever epidemic while rejecting his etiology of the disease. Others deprecated his therapies, such as Dr. Deveze, but agreed that the fever had local origins. Deveze had arrived on the refugee ship from Saint-Domingue which many accused of having carried the disease, but he thought it healthy. The doctors did not understand the origin or transmittal of the disease. Historians believe it was brought by refugees from Saint-Domingue, where it was endemic, and transmitted by mosquitoes between the infected and healthy persons. Dr. Kuhn advised drinking wine, "at first weaker wines, such as claret and Rhenish; if these cannot be had, Lisbon
Yellow fever vaccine and Brazil in 2017 have further increased demand, while straining global vaccine supply. Therefore, to vaccinate susceptible populations in preventive mass immunization campaigns during outbreaks, fractional dosing of the vaccine is being considered as a dose-sparing strategy to maximize limited vaccine supplies. Fractional dose vaccination refers to administration of a reduced volume of vaccine dose, which has been reconstituted as per manufacturer recommendations. The first practical use of fractional doses of the yellow fever vaccine was in response to the 2016 outbreak in the Democratic Republic of Congo. Yellow fever vaccine Yellow fever vaccine is a vaccine that protects against