Broad-spectrum antibiotic estimated 10-100 trillion multiple organisms that colonize the human body. As a side-effect of therapy, antibiotics can change the body's normal microbial content by attacking indiscriminately both the pathological and naturally occurring, beneficial or harmless bacteria found in the intestines, lungs and bladder. The destruction of the body's normal bacterial flora is thought to disrupt immunity, nutrition, and lead to a relative overgrowth in some bacteria or fungi. An overgrowth of drug-resistant microorganisms can lead to a secondary infection such as "Clostridium difficile" ("C. diff") or candidiasis ("thrush"). This side-effect is more likely with the use of broad-spectrum antibiotics, given
Fungi of Australia species are likely to form an important component of the natural checks and balances of native ecosystems, and may have their own distinctive conservation needs. There seems to have been no compilation of information about the rust fungi of Australia since the detailed monograph by McAlpine (2006). These fungi are parasites, mainly of flowering plants. Unlike the Agaricomycotina, they are usually small and easily missed by the untrained eye. These fungi are most easily noticed when they produce their fruiting structures, called sori, which are most often confined to the host flower, but may also sometimes be seen on fruits