Gamay The grape brought relief to the village growers following the decline of the Black Death. In contrast to the Pinot noir variety, Gamay ripened two weeks earlier and was less difficult to cultivate. It also produced a strong, fruitier wine in a much larger abundance. In July 1395, the Duke of Burgundy Philippe the Bold outlawed the cultivation of the grape, referring to it as the ""disloyal Gaamez"" that in spite of its ability to grow in abundance was full of ""very great and horrible harshness"", due in part to the variety's occupation of land that could be used for
Petite mutation petite negative mutants. Potentially, these yeasts have a different inheritance system in place for their mitchondrial genome than "S. cerevisiae" does. The frequency at which "S. castellii" spontaneously produces petites is similar to that of "S. cerevisiae", with the mitochondrial DNA of those petites being highly altered via deletion and rearrangement. Suppressive petites of "S. cerevisiae" are the most commonly observed spontaneously created mutants, whereas in "S. castellii," the most commonly observed spontaneous mutant is the neutral petite, further leading to speculation that the transference of this mutation differs between species. Petite mutation petite (ρ–) is a mutant first discovered