Mydriasis eye, and also to reduce painful ciliary muscle spasm (see cycloplegia). One effect of administration of a mydriatic is intolerance to bright light (photophobia). Purposefully-induced mydriasis via mydriatics is also used as a diagnostic test for Horner's syndrome. Mydriasis can be induced via modulation of adrenergic or cholinergic signalling. Within the adrenergic system, norepinephrine is a hormone and neurotransmitter responsible for regulating physiological processes in the body, including the involuntary muscles of the autonomic nervous system (such as the dilation or constriction of the pupil aperture via the muscles of the iris). Modulation of norepinephrine signalling can induce mydriasis. For
State River Widening The Leaf Label and at the end of the year began work on a new album, with ex-Laika mainstay Guy Fixsen assisting. That album, "Harps Old Master", was released in September 2006. State River Widening State River Widening, named after the title of a Chinese propaganda photo, are a London based trio, formed in May 1998, comprising multi-instrumentalists David Sheppard and Keiron Phelan, along with drummer/percussionist Jon Steele. Friends from school (in south London) Sheppard and Phelan began experimental recordings in 1996, soon hooking up with percussionist Steele to leaven their intertwining, Nick Drake-like acoustic guitars with vigorous yet dexterous