Pupillary response Pupillary response Pupillary response is a physiological response that varies the size of the pupil, via the optic and oculomotor cranial nerve. A constriction response (miosis), is the narrowing of the pupil, which may be caused by scleral buckles or drugs such as opiates/opioids or anti hypertension medications. Constriction of the pupil occurs when the circular muscle, controlled by the parasympathetic nervous system (PSNS), contracts. A dilation response (mydriasis), is the widening of the pupil and may be caused by adrenaline, anticholinergic agents or drugs such as MDMA, cocaine, amphetamines and some hallucinogenics. Dilation of the pupil occurs when the
Batman: The Widening Gyre release the remaining issues as a separate series to be called "Batman: Bellicosity", that was due in 2014, but to date, remains unreleased. In May 2009, it was announced that "Batman: The Widening Gyre" would be written by Kevin Smith and illustrated by Walt Flanagan. Months earlier, both had completed "". As Smith explained it, the series will have 12 issues split into two six-issue books. Book 1 was supposed to run from August 2009 to January 2010 and, after a six-month hiatus, Book 2 would run from July 2010 through December 2010. However, Book 1 was plagued by several