Mydriasis eye, and also to reduce painful ciliary muscle spasm (see cycloplegia). One effect of administration of a mydriatic is intolerance to bright light (photophobia). Purposefully-induced mydriasis via mydriatics is also used as a diagnostic test for Horner's syndrome. Mydriasis can be induced via modulation of adrenergic or cholinergic signalling. Within the adrenergic system, norepinephrine is a hormone and neurotransmitter responsible for regulating physiological processes in the body, including the involuntary muscles of the autonomic nervous system (such as the dilation or constriction of the pupil aperture via the muscles of the iris). Modulation of norepinephrine signalling can induce mydriasis. For
I Wouldn't Normally Do This Kind of Thing I Wouldn't Normally Do This Kind of Thing "I Wouldn't Normally Do This Kind of Thing" is the third single from Pet Shop Boys' fifth album "Very". It was released in the UK by Parlophone Records on 29 November 1993, where it eventually reached number 13 in the chart. It reached number 2 on the US Club chart where it was released in January 1994. It appears to describe a person, normally hesitant to unwind and show his feelings, who—because of some event in his life (possibly a love interest)—suddenly becomes willing to let it all hang out. It is