History of yellow fever 1,235 fatalities were recorded of an estimated 12,000 cases. Smaller outbreaks occurred in Saint-Nazaire in France, Swansea in Wales, and in other European port cities following the arrival of vessels carrying the mosquito vector. The first mention of the disease by the name "yellow fever" occurred in 1744. Many famous people, mostly during the 18th through the 20th centuries, contracted and then recovered from, or died of, yellow fever. The Yellow Fever Epidemic of 1793 struck during the summer in Philadelphia, Pennsylvania, where the highest fatalities in the United States were recorded. The disease probably was brought by refugees and
Yellow fever interferons, do not have a positive effect in patients. Asymptomatic treatment includes rehydration and pain relief with drugs such as paracetamol. Acetylsalicylic acid should not be given because of its anticoagulant effect, which can be devastating in the case of internal bleeding that can occur with yellow fever. Yellow fever is common in tropical and subtropical areas of South America and Africa. Worldwide, about 600 million people live in endemic areas. The WHO estimates 200,000 cases of disease and 30,000 deaths a year occur; the number of officially reported cases is far lower. An estimated 90% of the infections occur