Glucose cycle The glucose cycle can occur in liver cells due to a liver specific enzyme glucose-6-phosphatase, which catalyse the dephosphorylation of glucose 6-phosphate back to glucose. Glucose-6-phosphate is the product of glycogenolysis or gluconeogenesis, where the goal is to increase free glucose in the blood due body being in catabolic state. Other cells such as muscle and brain cells do not contain glucose 6-phosphatase. As a result, any glucose 6-phosphate produced in those cells is committed to cellular metabolic pathways, primarily pentose phosphate pathway or glycolysis. Flux through the glucose cycle is regulated by several hormones including insulin and glucagon as
Blood glucose monitoring the absolute value of the blood glucose level given by the system as well as any trend in the blood glucose levels. For example, a patient using CGM with a blood glucose of 100 mg/dl on their CGM system might take no action if their blood glucose has been consistent for several readings, while a patient with the same blood glucose level but whose blood glucose has been dropping steeply in a short period of time might be advised to perform a fingerstick test to check for hypoglycemia. Continuous monitoring allows examination of how the blood glucose level reacts to