Glycogen storage disease type I similar, but Ib incurs a few additional problems (described below). Glycogen in liver and (to a lesser degree) kidneys serves as a form of stored, rapidly accessible glucose, so that the blood glucose level can be maintained between meals. For about 3 hours after a carbohydrate-containing meal, high insulin levels direct liver cells to take glucose from the blood, to convert it to glucose-6-phosphate (G6P) with the enzyme glucokinase, and to add the G6P molecules to the ends of chains of glycogen (glycogen synthesis). Excess G6P is also shunted into production of triglycerides and exported for storage in adipose tissue
Stress in early childhood the skin and gut. This allows a sufficient amount of blood to access the brain and muscles. Also, epinephrine initiates the breakdown of glycogen in the liver, in turn increasing blood glucose levels. This energy source allows humans to enact defensive responses due to stress. In the human body, the steps that lead to the release of glucocorticoids such as cortisol begin with the release of corticotropin releasing hormone (CRH) and arginine vasopressin (AVP). These hormones travel through the blood vessels to the anterior pituitary gland of the brain. At this location, adrenocorticotropic hormone (ACTH) is released. ACTH binds to