Yellow fever in Buenos Aires the mosquito "Aedes aegypti", which was responsible of transmitting Yellow Fever. A witness to the epidemic of 1871, named Mardoqueo Navarro, wrote on April 13 the following description in his diary: Since 1881, thanks to Cuban physician Carlos Finlay, it was known that the transmitting agent of Yellow Fever was mosquito "Aedes aegypti". Before that discovery, doctors attributed the cause of many epidemics to what they called "miasmas" floating in the air. Yellow Fever (or "black vomit", as it was called due to bleeding that occurs in the gastrointestinal) caused an epidemic in Buenos Aires in 1852. However, by a
Yellow fever vaccine and Brazil in 2017 have further increased demand, while straining global vaccine supply. Therefore, to vaccinate susceptible populations in preventive mass immunization campaigns during outbreaks, fractional dosing of the vaccine is being considered as a dose-sparing strategy to maximize limited vaccine supplies. Fractional dose vaccination refers to administration of a reduced volume of vaccine dose, which has been reconstituted as per manufacturer recommendations. The first practical use of fractional doses of the yellow fever vaccine was in response to the 2016 outbreak in the Democratic Republic of Congo. Yellow fever vaccine Yellow fever vaccine is a vaccine that protects against