Alkaloid ("Agonopterix alstroemeriana)." This moth feeds on its highly toxic and alkaloid-rich host plant poison hemlock ("Conium maculatum") during its larval stage. "A. asltroemeriana" may benefit twofold from the toxicity of the naturally-occurring alkaloids, both through the unpalatability of the species to predators and through the ability of "A. alstroemeriana" to recognize "Conium maculatum" as the correct location for oviposition. Medical use of alkaloid-containing plants has a long history, and, thus, when the first alkaloids were isolated in the 19th century, they immediately found application in clinical practice. Many alkaloids are still used in medicine, usually in the form of salts,
U Should've Known Better producers, which included Dallas Austin, production team Soulshock & Karlin, Bryan Michael Cox, and Rodney Jerkins and his Darkchild crew. Though she "had never thought about writing much" by then, her producers encouraged the singer to intensify her work on the "All Eyez on Me" album and to write and contribute own lyrics and ideas to the songs, one of which was the ballad "U Should've Known Better." Monica penned the song along with Harold Lilly and longtime contributor Jermaine Dupri, while production on the track was helmed by Dupri and Bryan Michael Cox. "U Should've Known Better" was mixed