Transfer factor factors are contraindicated for women who are pregnant or breastfeeding. When human- and bovine-derived transfer factor are generated from blood cells they carry the potential for blood-borne disease such as HIV/AIDS and Hepatitis C. Colostrum is a form of milk produced by the mammary glands of mammals (including humans) in late pregnancy. Colostrum also contains multiple immune modulating molecules, including high antibody levels. Based on studies noting an overlap in the observed in vitro effects between a molecule contained in colostrum called colostrinin and the dialyzable leukocyte extract mentioned above, a hypothesis formed that the two were the same. There
Colostrum as lactoferrin and hemopexin, which binds free heme in the body. The Isle of Man had a local delicacy called "Groosniuys", a pudding made with colostrum. Hyperimmune colostrum is natural bovine colostrum collected from a population of cows immunized repeatedly with a specific pathogen. The colostrum is collected within 24 hours of the cow giving birth. Antibodies towards the specific pathogens or antigens that were used in the immunization are present in higher levels than in the population before treatment. Although some papers have been published stating that specific human pathogens were just as high as in hyperimmune colostrum, and