Apamin Apamin Apamin is an 18 amino acid peptide neurotoxin found in apitoxin (bee venom). Dry bee venom consists of 2–3% of apamin. Apamin selectively blocks SK channels, a type of Ca-activated K channel expressed in the central nervous system. Toxicity is caused by only a few amino acids, these are cysteine, lysine, arginine, arginine and histidine. These amino acids are involved in the binding of apamin to the Ca-activated K channel. Due to its specificity for SK channels, apamin is used as a drug in biomedical research to study the electrical properties of SK channels and their role in the
Bubble sort generic bad algorithm". Donald Knuth, in "The Art of Computer Programming", concluded that "the bubble sort seems to have nothing to recommend it, except a catchy name and the fact that it leads to some interesting theoretical problems", some of which he then discusses. Bubble sort is asymptotically equivalent in running time to insertion sort in the worst case, but the two algorithms differ greatly in the number of swaps necessary. Experimental results such as those of Astrachan have also shown that insertion sort performs considerably better even on random lists. For these reasons many modern algorithm textbooks avoid using