Yellow fever in Buenos Aires the mosquito "Aedes aegypti", which was responsible of transmitting Yellow Fever. A witness to the epidemic of 1871, named Mardoqueo Navarro, wrote on April 13 the following description in his diary: Since 1881, thanks to Cuban physician Carlos Finlay, it was known that the transmitting agent of Yellow Fever was mosquito "Aedes aegypti". Before that discovery, doctors attributed the cause of many epidemics to what they called "miasmas" floating in the air. Yellow Fever (or "black vomit", as it was called due to bleeding that occurs in the gastrointestinal) caused an epidemic in Buenos Aires in 1852. However, by a
Yellow fever culture the virus and won a Nobel Prize in 1951 for this achievement. A French team developed the French neurotropic vaccine (FNV), which was extracted from mouse brain tissue. Since this vaccine was associated with a higher incidence of encephalitis, FNV was not recommended after 1961. Vaccine 17D is still in use, and more than 400 million doses have been distributed. Little research has been done to develop new vaccines. Some researchers worry that the 60-year-old technology for vaccine production may be too slow to stop a major new yellow-fever epidemic. Newer vaccines, based on vero cells, are in development