Transfer factor factors are contraindicated for women who are pregnant or breastfeeding. When human- and bovine-derived transfer factor are generated from blood cells they carry the potential for blood-borne disease such as HIV/AIDS and Hepatitis C. Colostrum is a form of milk produced by the mammary glands of mammals (including humans) in late pregnancy. Colostrum also contains multiple immune modulating molecules, including high antibody levels. Based on studies noting an overlap in the observed in vitro effects between a molecule contained in colostrum called colostrinin and the dialyzable leukocyte extract mentioned above, a hypothesis formed that the two were the same. There
Hasse invariant of a quadratic form Hasse invariant of a quadratic form In mathematics, the Hasse invariant (or Hasse–Witt invariant) of a quadratic form "Q" over a field "K" takes values in the Brauer group Br("K"). The name "Hasse–Witt" comes from Helmut Hasse and Ernst Witt. The quadratic form "Q" may be taken as a diagonal form Its invariant is then defined as the product of the classes in the Brauer group of all the quaternion algebras This is independent of the diagonal form chosen to compute it. It may also be viewed as the second Stiefel–Whitney class of "Q". The invariant may be computed for