Apamin therapeutic effect on Parkinson's disease. Dopamine, which is depleted in this disease, will be released from midbrain dopaminergic neurons when these SK channels are inhibited. SK channels have also been proposed as targets for the treatment of epilepsy, emotional disorders and schizophrenia. Apamin Apamin is an 18 amino acid peptide neurotoxin found in apitoxin (bee venom). Dry bee venom consists of 2–3% of apamin. Apamin selectively blocks SK channels, a type of Ca-activated K channel expressed in the central nervous system. Toxicity is caused by only a few amino acids, these are cysteine, lysine, arginine, arginine and histidine. These amino
Sort (Unix) name the output file because it was used to sort a file in place. In Version 5, Thompson invented "-" to represent standard input. $ cat "phonebook" The codice_1 option makes the program sort according to numerical value. The command produces output that starts with a number, the file size, so its output can be piped to to produce a list of files sorted by (ascending) file size: Use the codice_2 option to sort on a certain column. For example, use "codice_3" to sort on the second column). In old versions of sort, the codice_4 option made the program sort