Livermore Valley AVA unique east-west orientation, unlike many other winegrowing valleys. Due to a reliable onshore afternoon/evening breeze off of the San Francisco Bay a wide fluctuation in temperature between sites and a large diurnal temperature swing occur. Livermore Valley is considered a Winkler Region III grape growing zone with temperatures comparable to northern Napa Valley appellations such as St. Helena or Calistoga. The relatively obscure Petite Sirah grape produced Livermore's best historically known red wine, although the climate also makes for interesting dessert wines as well as excellent Cabernet Sauvignon, Merlot and Rhone varieties. The original plantings of Sémillon and Sauvignon blanc
Petite mutation be induced using a variety of mutagens, including DNA intercalating agents, as well as chemicals that can interfere with DNA synthesis in growing cells. Mutagens that create Petites are implicated in increased rates of degenerative diseases and in the aging process. A mutation that produces small (petite" > petite) anaerobic-like colonies had shown first in Yeast Saccharomyces cerevisiae and described by Boris Ephrussi and his co-workers in 1949 in Gif-sur-Yvette, France. The cells of petite colonies were smaller than those of wild-type colonies, but the term “petite” refers only to colony size and not the individual cell size. Over 50