Irvine Welsh Trust for social inclusion in Edinburgh. In "Crime", Ray Lennox (from Welsh's previous work, "Filth") is recovering from a mental breakdown induced by occupational stress and cocaine abuse, and a particularly horrifying child sex murder case back in Edinburgh. The story takes place in Florida. In 2012 Welsh published a prequel to "Trainspotting", titled "Skagboys". Set in Leith in the early 1980s, it introduces the "Trainspotting" characters and follows them as they fall into heroin addiction. Given as a series of linked short stories, the book is also interspersed with brief commentaries on contemporary British politics. In particular, the consequences
Heroin used and faster the route of administration used, the higher potential risk for psychological addiction. Large doses of heroin can cause fatal respiratory depression, and the drug has been used for suicide or as a murder weapon. The serial killer Harold Shipman used diamorphine on his victims, and the subsequent Shipman Inquiry led to a tightening of the regulations surrounding the storage, prescribing and destruction of controlled drugs in the UK. John Bodkin Adams is also known to have used heroin as a murder weapon. Because significant tolerance to respiratory depression develops quickly with continued use and is lost just