Hypotonic hyponatremia dramatic increase the serum sodium concentration and place the patient at risk for so-called "central pontine myelinolysis" (CPM). That disorder is characterized by major neurologic damage, often of a permanent nature. Because of the risk of CPM, people with low volume hyponatremia may eventually require water infusion as well as volume replacement. Doing so lessens the chance of a too rapid increase of the serum sodium level as blood volume rises and ADH levels fall. In people who are volume depleted, i.e., their blood volume is too low, ADH secretion is increased, since volume depletion is a potent stimulus for
Blood libel Blood libel Blood libel (also blood accusation) is an antisemitic canard accusing Jews of kidnapping and murdering the children of Christians in order to use their blood as part of religious rituals. Historically, these claims—alongside those of well poisoning and host desecration—have been a major theme of the persecution of Jews in Europe. Blood libels typically say that Jews require human blood for the baking of matzos for Passover, although this element was allegedly absent in the earliest cases which claimed that then-contemporary Jews reenacted the crucifixion. The accusations often assert that the blood of the children of Christians is