Osmotherapy inhibits these channels. Vasopressin receptors activated by vasopressin are found on the basolateral membrane of the cells lining the collecting ducts of the kidneys. Aneurysmal subarachnoid hemorrhage(aSAH) results in hyponatremia which leads to water retention and antidiuretic hormone release causing increase in intracranial pressure and formation of cerebral edema. This can be prevented by administration of conivaptan, a safe FDA approved drug that treats euvolemic hyponatremia. Through the process of aquaresis, conivapten which is a vasopressin receptor antagonist improves serum sodium concentration while eliminating free water without having any negative effect on systolic blood pressure and pulse rate. Since it
Fetal bovine serum which they can survive, grow, and divide. FBS is not a fully defined media component, and as such may vary in composition between batches. As a result, serum free and chemically defined media (CDM) have been developed as a matter of good laboratory practice. Fetal bovine serum is a by-product of the dairy industry. Fetal bovine serum, as with the vast majority of animal serum used in cell culture, is produced from blood collected at commercial slaughterhouses from dairy cattle that also supply meat intended for human consumption. The first stage of the production process for fetal bovine serum is