German Americans especially regarding pastries, meats and sausages, and above all, beer. Frankfurters (or "wieners", originating from Frankfurt am Main and Vienna, respectively), hamburgers, bratwurst, sauerkraut, and strudel are common dishes. German bakers introduced the pretzel, which is popular across the United States. Germans introduced America to lager, the most-produced beer style in the United States, and have been the dominant ethnic group in the beer industry since 1850. The oldest extant brewery in the United States is D. G. Yuengling & Son of Pottsville, Pennsylvania (approximately 80 miles northwest of Philadelphia), founded in 1829 by an immigrant from Aldingen in what
Time-varying covariate Time-varying covariate A time-varying covariate (also called time-dependent covariate) is a term used in statistics, particularly in survival analyses. It reflects the phenomenon that a covariate is not necessarily constant through the whole study. For instance, if one wishes to examine the link between area of residence and cancer, this would be complicated by the fact that study subjects move from one area to another. The area of residency could then be introduced in the statistical model as a time-varying covariate. In survival analysis, this would be done by splitting each study subject into several observations, one for each area