Apamin therapeutic effect on Parkinson's disease. Dopamine, which is depleted in this disease, will be released from midbrain dopaminergic neurons when these SK channels are inhibited. SK channels have also been proposed as targets for the treatment of epilepsy, emotional disorders and schizophrenia. Apamin Apamin is an 18 amino acid peptide neurotoxin found in apitoxin (bee venom). Dry bee venom consists of 2–3% of apamin. Apamin selectively blocks SK channels, a type of Ca-activated K channel expressed in the central nervous system. Toxicity is caused by only a few amino acids, these are cysteine, lysine, arginine, arginine and histidine. These amino
Venom (Marvel Comics character) its new host, Lee Price, launching volume 3 of the "Venom" comic book series. The series ran for six issues total (Nov. 2016-April 2017). Eddie Brock is able to regain the Venom symbiote at the conclusion of the series, returning the "Venom" comic book title to volume 1 with issue #150. The Venom Symbiote approaches Mac Gargan, the villain formerly known as Scorpion, and offered him new abilities as the second Venom. Gargan bonded with the creature, which would later give him an extra edge as part of Norman Osborn's Sinister Twelve. As the Avengers dealt with the rest of