Yellow fever Because of this sylvatic cycle, yellow fever cannot be eradicated except by eradicating the mosquitoes that serve as vectors. In Africa, a third infectious cycle known as "savannah cycle" or intermediate cycle, occurs between the jungle and urban cycles. Different mosquitoes of the genus "Aedes" are involved. In recent years, this has been the most common form of transmission of yellow fever in Africa. Concern exists about yellow fever spreading to southeast Asia, where its vector "A. aegypti" already occurs. After transmission from a mosquito, the viruses replicate in the lymph nodes and infect dendritic cells in particular. From there,
1793 Philadelphia yellow fever epidemic vector of the 1793 plague in Philadelphia (and other Atlantic ports) was the British merchant ship "Hankey", which had fled the West African colony of Bolama (an island off West Africa, present day Guinea-Bissau) the previous November, trailing yellow fever at every port of call in the Caribbean and eastern Atlantic seaboard. See: "The Ship of Death: The Voyage That Changed the Atlantic World". After two weeks and an increasing number of fever cases, Dr. Benjamin Rush, a doctor's apprentice during the city's 1762 yellow fever epidemic, saw the pattern; he recognized that yellow fever had returned. Rush alerted his