Honey bee as apitoxin, carries several active components, the most abundant of which is melittin, and the most biologically active are enzymes, particularly phospholipase A2. Bee venom is under laboratory and clinical research for its potential properties and uses in reducing risks for adverse events from bee venom therapy, rheumatoid arthritis, and use as an immunotherapy for protection against allergies from insect stings. Bee venom products are marketed in many countries, but, as of 2018, there are no approved clinical uses for these products which carry various warnings for potential allergic reactions. With an increased number of honey bees in a specific
Platypus venom characteristic uniquely, the platypus simply inherited its venom from its distant ancestors. Rather than being a unique outlier, the platypus is the last demonstration of what was once a common mammalian characteristic, and it can be used as a model for non-therian mammals and their venom delivery and properties. The venom is produced in the crural glands of the male, which are kidney-shaped alveolar glands located in the upper thigh connected by a thin-walled duct to a calcaneus spur, or calcar, on each hind limb. Female platypuses, in common with echidnas, have rudimentary spur buds that do not develop (dropping