Yellow fever in the Golgi apparatus by the host protein furin, which cleaves prM to M. This releases E from the complex which can now take its place in the mature, infectious virion. Yellow fever virus is mainly transmitted through the bite of the yellow fever mosquito "Aedes aegypti", but other mostly "Aedes" mosquitoes such as the tiger mosquito ("Aedes albopictus") can also serve as a vector for this virus. Like other arboviruses which are transmitted by mosquitoes, the yellow fever virus is taken up by a female mosquito when it ingests the blood of an infected human or another primate. Viruses
Yellow fever vaccine of age. Those travelling to areas where the disease occurs should also be immunized. Additional doses after the first are generally not needed. Yellow fever vaccine is generally safe. This includes in those with HIV infection but without symptoms. Mild side effects may include headache, muscle pains, pain at the injection site, fever, and rash. Severe allergies occur in about eight per million doses, serious neurological problems occur in about four per million doses, and organ failure occurs in about three per million doses. It is likely safe in pregnancy and therefore recommended among those who will be potentially exposed.