Erythema toxicum neonatorum Erythema toxicum neonatorum Erythema toxicum neonatorum (also known as erythema toxicum, urticaria neonatorum and toxic erythema of the newborn) is a common rash in neonates. It appears in up to half of newborns carried to term, usually between day 2–5 after birth; it does not occur outside the neonatal period. Erythema toxicum is characterized by blotchy red spots on the skin with overlying white or yellow papules or pustules. These lesions may be few or numerous. The eruption typically resolves within first two weeks of life and frequently individual lesions will appear and disappear within minutes or hours. It is
Human skin or strata: Blood capillaries are found beneath the epidermis, and are linked to an arteriole and a venule. Arterial shunt vessels may bypass the network in ears, the nose and fingertips. About 70% of all human protein-coding genes are expressed in the skin. Almost 500 genes have an elevated pattern of expression in the skin. There are less than 100 genes that are specific for the skin and these are expressed in the epidermis. An analysis of the corresponding proteins show that these are mainly expressed in keratinocytes and have functions related to squamous differentiation and cornification. The dermis is