Yellow fever in Buenos Aires the mosquito "Aedes aegypti", which was responsible of transmitting Yellow Fever. A witness to the epidemic of 1871, named Mardoqueo Navarro, wrote on April 13 the following description in his diary: Since 1881, thanks to Cuban physician Carlos Finlay, it was known that the transmitting agent of Yellow Fever was mosquito "Aedes aegypti". Before that discovery, doctors attributed the cause of many epidemics to what they called "miasmas" floating in the air. Yellow Fever (or "black vomit", as it was called due to bleeding that occurs in the gastrointestinal) caused an epidemic in Buenos Aires in 1852. However, by a
Yellow fever ribavirin is an effective early treatment of many pathological features of the disease. Ribavirin treatment during the first five days after virus infection improved survival rates, reduced tissue damage in the liver and spleen, prevented hepatocellular steatosis, and normalised levels of alanine aminotransferase, a liver damage marker. The mechanism of action of ribavirin in reducing liver pathology in yellow fever virus infection may be similar to its activity in treatment of hepatitis C, a related virus. Because ribavirin had failed to improve survival in a virulent rhesus model of yellow fever infection, it had been previously discounted as a possible