1793 Philadelphia yellow fever epidemic Philadelphia forced evacuation of certain neighborhoods and placed refugees in supervised camps. After the epidemic, the city inspected all houses and destroyed those it deemed unhealthy. American doctors did not identify the vector of yellow fever until the late nineteenth century. In 1881 Carlos Finlay, a Cuban doctor, argued that mosquito bites caused yellow fever; he credited Rush's published account of the 1793 epidemic for giving him the idea. He said that Rush had written: "Mosquitoes (the usual attendants of a sickly autumn) were uncommonly numerous..." In the late 1880s, Finlay's theories were confirmed in Cuba by experiments of the
Yellow fever yellow fever virus became the first human virus to be isolated. Yellow fever begins after an incubation period of three to six days. Most cases only cause a mild infection with fever, headache, chills, back pain, fatigue, loss of appetite, muscle pain, nausea, and vomiting. In these cases, the infection lasts only three to four days. In 15% of cases, however, people enter a second, toxic phase of the disease with recurring fever, this time accompanied by jaundice due to liver damage, as well as abdominal pain. Bleeding in the mouth, the eyes, and the gastrointestinal tract cause vomit containing