Hyponatremia feedback loop is overwhelmed by increased fluid intake, 2) the feedback loop malfunctions such that ADH is always "turned on"; 3) the receptors in the kidney are always "open" regardless of there being no signal from ADH to be open; or 4) there is an increased ADH even though there is no normal stimulus (elevated serum sodium) for ADH to be increased. Hyponatremia occurs in one of two ways: either the osmoreceptor-aquaporin feedback loop is "overwhelmed", or it is "interrupted". If it is interrupted, it is either "related" or "not related" to ADH. If the feedback system is overwhelmed, this
Antireticular cytotoxic serum p. 28 Antireticular cytotoxic serum Anti-reticular Cytotoxic Serum is made from the blood of a rabbit that has been injected with homogenized cadaver spleen and rib marrow. In small quantities it can aid animal growth, but is toxic in large doses. It was first developed by Alexander A. Bogomolets in 1936. "It was a "miracle" that Professor Bogomolets made dying people walk with blood of cadavers circulating through their bodies, or hoped to extend our life-span for 150 years with the help of the A.C.S serum" - Red Miracle: The Story of Soviet Medicine by Edward Podolsky "World Book Encyclopedia",