Apamin Apamin Apamin is an 18 amino acid peptide neurotoxin found in apitoxin (bee venom). Dry bee venom consists of 2–3% of apamin. Apamin selectively blocks SK channels, a type of Ca-activated K channel expressed in the central nervous system. Toxicity is caused by only a few amino acids, these are cysteine, lysine, arginine, arginine and histidine. These amino acids are involved in the binding of apamin to the Ca-activated K channel. Due to its specificity for SK channels, apamin is used as a drug in biomedical research to study the electrical properties of SK channels and their role in the
Proxmap sort Proxmap sort ProxmapSort, or Proxmap sort, is a sorting algorithm that works by partitioning an array of data items, or keys, into a number of "subarrays" (termed buckets, in similar sorts). The name is short for computing a "proximity map," which indicates for each key K the beginning of a subarray where K will reside in the final sorted order. Keys are placed into each subarray using insertion sort. If keys are "well distributed" among the subarrays, sorting occurs in linear time. The computational complexity estimates involve the number of subarrays and the proximity mapping function, the "map key," used.