Pupillary response Pupillary response Pupillary response is a physiological response that varies the size of the pupil, via the optic and oculomotor cranial nerve. A constriction response (miosis), is the narrowing of the pupil, which may be caused by scleral buckles or drugs such as opiates/opioids or anti hypertension medications. Constriction of the pupil occurs when the circular muscle, controlled by the parasympathetic nervous system (PSNS), contracts. A dilation response (mydriasis), is the widening of the pupil and may be caused by adrenaline, anticholinergic agents or drugs such as MDMA, cocaine, amphetamines and some hallucinogenics. Dilation of the pupil occurs when the
What a Pushkin, what a son of a bitch! What a Pushkin, what a son of a bitch! "What a Pushkin, what a son of a bitch!" (; sometimes separated by exclamation mark instead of comma) is a catchphrase and winged word from Alexander Pushkin's correspondence with one of his friends, poet Pyotr Vyazemsky. The phrase commonly expresses a joy after finishing one's work and appears particularly in several Russian literary works. In a letter dated circa November 7 or beginning of October, 1825 Pushkin, celebrating his finished drama "Boris Godunov" wrote to Vyazemsky: That was preceded by what Pushkin wrote to Vyazemsky on July 13 of the same