Apamin therapeutic effect on Parkinson's disease. Dopamine, which is depleted in this disease, will be released from midbrain dopaminergic neurons when these SK channels are inhibited. SK channels have also been proposed as targets for the treatment of epilepsy, emotional disorders and schizophrenia. Apamin Apamin is an 18 amino acid peptide neurotoxin found in apitoxin (bee venom). Dry bee venom consists of 2–3% of apamin. Apamin selectively blocks SK channels, a type of Ca-activated K channel expressed in the central nervous system. Toxicity is caused by only a few amino acids, these are cysteine, lysine, arginine, arginine and histidine. These amino
Velocette Venom secured the world record. The publicity was very important for Velocette, as the success revived sales of the Venom, which went on to become one of Velocette's best-selling motorcycles. The Venom which set the 24-hour world record is on display at the British National Motorcycle Museum. At the 1964 Thruxton 500 endurance race, Velocette Venoms took the first three places in the 500 cc category, with winners Alan Harris and Howard German on a Stevens-entered machine finishing third overall in with the larger-capacity machines. A specially styled, high-performance 'Thruxton' version of the Venom with high-quality equipment was announced in late