Apamin therapeutic effect on Parkinson's disease. Dopamine, which is depleted in this disease, will be released from midbrain dopaminergic neurons when these SK channels are inhibited. SK channels have also been proposed as targets for the treatment of epilepsy, emotional disorders and schizophrenia. Apamin Apamin is an 18 amino acid peptide neurotoxin found in apitoxin (bee venom). Dry bee venom consists of 2–3% of apamin. Apamin selectively blocks SK channels, a type of Ca-activated K channel expressed in the central nervous system. Toxicity is caused by only a few amino acids, these are cysteine, lysine, arginine, arginine and histidine. These amino
VeNom Coding Group and we will make the necessary adjustments if required. We are currently working on other lists (procedures etc.) and these will be added to the VENOM codes in due course. The VENOM codes are a long list of conditions (Term name) identified by their unique numeric codes (Data Dictionary Id). There is a label field to identify the type of term (Container and Container ID–e.g. diagnosis, presenting complaint, administrative task etc.). The Top level modelling field includes the parent grouping / body system for each term. There is also a CRIS Active flag which is elected if the PMS prefers