Central pontine myelinolysis scenario the CPM is caused by polydipsia leading to low blood sodium levels (hyponatremia). In schizophrenic patients with psychogenic polydipsia, inadequate thirst reception leads to excessive water intake, severely diluting serum sodium. With this excessive thirst combined with psychotic symptoms, brain damage such as CPM may result from hyperosmolarity caused by excess intake of fluids, (primary polydipsia) although this is difficult to determine because such patients are often institutionalised and have a long history of mental health conditions. It has been observed following hematopoietic stem cell transplantation. CPM may also occur in patients prone to hyponatraemia affected by: The currently
Exercise-associated hyponatremia drink beyond the dictates of thirst can be deadly." Similarly, authors of the Statement of the Third International Exercise-Associated Hyponatremia Consensus Development Conference claim this advice has "facilitated inadvertent overdrinking and pathological dilutional EAH." Critics of the ACSM's view have questioned their motives, pointing out that Gatorade is one of the organizations "platinum sponsors." Treatments are focused on the underlying cause of hyponatremia and include When EAH is treated early, complete recovery is expected. In addition to the above treatments, athletes experiencing EAH encephalopathy may also receive high-flow oxygen and a rapid infusion of 100 ml of 3% NaCl to