Hyponatremia vasopressin receptor antagonists (vaptans), such as conivaptan, may be slightly more effective than fluid restriction in those with high volume or normal volume hyponatremia. They should not be used in people with low volume. Their use in SIADH is unclear. Demeclocycline, while sometimes used for SIADH, has significant side effects including potential kidney problems and sun sensitivity. In many people it has no benefit while in others it can result in overcorrection and high blood sodium levels. Daily use of urea by mouth, while not commonly used due to the taste, has tentative evidence in SIADH. It, however, is not
Human Element believes it is the fear that the walking dead instill in the survivors, who lead them to do unreasonable things to survive. The game focuses on the survivors more so than the zombies, "the human element", and takes place 35 years after the zombie apocalypse began. It can be played across multiple devices; an example given is that one player could play the console version for hundreds of hours, just for the action, whereas an intelligent class player, playing on a tablet, can join into the previous player's alliance and scavenge for them, and then benefit from the buffs given