Transfer factor factors are contraindicated for women who are pregnant or breastfeeding. When human- and bovine-derived transfer factor are generated from blood cells they carry the potential for blood-borne disease such as HIV/AIDS and Hepatitis C. Colostrum is a form of milk produced by the mammary glands of mammals (including humans) in late pregnancy. Colostrum also contains multiple immune modulating molecules, including high antibody levels. Based on studies noting an overlap in the observed in vitro effects between a molecule contained in colostrum called colostrinin and the dialyzable leukocyte extract mentioned above, a hypothesis formed that the two were the same. There
Colostrum bacteria. It is also a major immunological defence mechanism, detecting natural commensals and triggering immune response when toxic microbes are present. Failure of homeostasis due to trauma, drugs and infectious microbes not only damages the gut but can lead to influx of damaging agents into the bloodstream. These mechanisms have relevance for multiple conditions affecting all areas of the world and socioeconomic groups such as ulcers, inflammation, and infectious diarrhoea. There is currently much interest in the potential value of colostrum for the prevention and treatment of these conditions as it is derived from natural sources and can influence damaging