Exercise-associated hyponatremia cells in one area begin to increase in size, swelling occurs in the affected area. Swelling is commonly observed in hands, legs, and feet. Sodium is also important in regulating the amount of water that passes through the blood-brain barrier. Decreased sodium blood levels result in increased permeability of water across the blood-brain barrier. This increased influx of water causes brain swelling which leads to severe neurological symptoms. EAH is categorized by having a blood serum or plasma sodium level below normal, which is less than 135 mmol/l. Asymptomatic EAH is not normally detected unless the athlete has had a
Serum free light-chain measurement Serum free light-chain measurement Immunoglobulin light chains that are circulating in serum in a free (unbound) state are called free light chains (FLCs). Measurement of the serum level of FLCs became practical as a clinical blood test in recent decades. These tests are used as an aid in the diagnosis and monitoring of multiple myeloma and related disorders. There are two types of immunoglobulin light chain produced in humans, designated by the Greek letters kappa (κ) and lambda (λ). Comparing the ratio of κ FLCs to λ FLCs in a person's serum against reference ranges indicates whether that person may