Diabetes mellitus one group, whereas type 2 encompasses four categories. This is hoped to improve diabetes treatment by tailoring it more specifically to the subgroups. Insulin is the principal hormone that regulates the uptake of glucose from the blood into most cells of the body, especially liver, adipose tissue and muscle, except smooth muscle, in which insulin acts via the IGF-1. Therefore, deficiency of insulin or the insensitivity of its receptors play a central role in all forms of diabetes mellitus. The body obtains glucose from three main sources: the intestinal absorption of food; the breakdown of glycogen (glycogenolysis), the storage form
Absorptive state Absorptive state Absorptive state is the period in which the gastrointestinal tract is full and the anabolic processes exceed catabolism. The fuel used for this process is glucose. Carbohydrates - Simple sugars are sent to the liver where they are converted to glucose. The glucose then travels to the blood or is converted to glycogen and fat (triglyceride). The glycogen and fat will be stored in the liver and adipose tissue, respectively, as reserves for the post-absorptive state. The remaining glucose is taken in for use by body cells or stored in skeletal muscle as glycogen. Triglycerides - Chylomicrons, the