Apamin therapeutic effect on Parkinson's disease. Dopamine, which is depleted in this disease, will be released from midbrain dopaminergic neurons when these SK channels are inhibited. SK channels have also been proposed as targets for the treatment of epilepsy, emotional disorders and schizophrenia. Apamin Apamin is an 18 amino acid peptide neurotoxin found in apitoxin (bee venom). Dry bee venom consists of 2–3% of apamin. Apamin selectively blocks SK channels, a type of Ca-activated K channel expressed in the central nervous system. Toxicity is caused by only a few amino acids, these are cysteine, lysine, arginine, arginine and histidine. These amino
Alternative versions of Venom years from current comics continuity, Venom has been posing as "Edward Saks", the aide to the Mayor of New York. "Edward" has been manipulating the city ever since Spider-Man's disappearance in preparation for his eventual return; in the process, he had re-enlisted the Sinister Six, replicated his symbiote thousands of times (chalking it up to being "lonely"), and built a security system named "WEBB" which prevents New York citizens from escaping from the city, trapping them while allegedly protecting them from the outside world. Upon meeting him, Venom is quick to berate Spider-Man for abandoning him all those years ago