Yellow fever in Buenos Aires the mosquito "Aedes aegypti", which was responsible of transmitting Yellow Fever. A witness to the epidemic of 1871, named Mardoqueo Navarro, wrote on April 13 the following description in his diary: Since 1881, thanks to Cuban physician Carlos Finlay, it was known that the transmitting agent of Yellow Fever was mosquito "Aedes aegypti". Before that discovery, doctors attributed the cause of many epidemics to what they called "miasmas" floating in the air. Yellow Fever (or "black vomit", as it was called due to bleeding that occurs in the gastrointestinal) caused an epidemic in Buenos Aires in 1852. However, by a
Yellow fever serves as a molecular signal to stall the exonuclease and is the only viral requirement for subgenomic flavivirus RNA (sfRNA) production. The sfRNAs are a result of incomplete degradation of the viral genome by the exonuclease and are important for viral pathogenicity. Yellow fever belongs to the group of hemorrhagic fevers. The viruses infect, amongst others, monocytes, macrophages, and dendritic cells. They attach to the cell surface via specific receptors and are taken up by an endosomal vesicle. Inside the endosome, the decreased pH induces the fusion of the endosomal membrane with the virus envelope. The capsid enters the cytosol,