Central pontine myelinolysis scenario the CPM is caused by polydipsia leading to low blood sodium levels (hyponatremia). In schizophrenic patients with psychogenic polydipsia, inadequate thirst reception leads to excessive water intake, severely diluting serum sodium. With this excessive thirst combined with psychotic symptoms, brain damage such as CPM may result from hyperosmolarity caused by excess intake of fluids, (primary polydipsia) although this is difficult to determine because such patients are often institutionalised and have a long history of mental health conditions. It has been observed following hematopoietic stem cell transplantation. CPM may also occur in patients prone to hyponatraemia affected by: The currently
Human Element engage and impact in the scenarios you will be presented with on a physical and moral level that you approach this world." The game was announced on June 1, 2012, and more details were released in the July edition of "Game Informer". On July 19, 2012, Robotoki's president Robert Bowling announced that "Human Element" would have an episodic prequel released exclusively on the Ouya, as a first-party title. But it was later announced that the studio decided to cancel the Ouya version of Human Element "very early on" and switch focus to the open-world experience on other more powerful platforms.