History of yellow fever 1,235 fatalities were recorded of an estimated 12,000 cases. Smaller outbreaks occurred in Saint-Nazaire in France, Swansea in Wales, and in other European port cities following the arrival of vessels carrying the mosquito vector. The first mention of the disease by the name "yellow fever" occurred in 1744. Many famous people, mostly during the 18th through the 20th centuries, contracted and then recovered from, or died of, yellow fever. The Yellow Fever Epidemic of 1793 struck during the summer in Philadelphia, Pennsylvania, where the highest fatalities in the United States were recorded. The disease probably was brought by refugees and
Yellow fever vaccine It should not be given to those with very poor immune function. Yellow fever vaccine came into use in 1938. It is on the World Health Organization's List of Essential Medicines, the most effective and safe medicines needed in a health system. The wholesale price in the developing world is between US$4.30 and US$21.30 per dose as of 2014. In the United States it costs between US$50 and US$100. The vaccine is made from weakened yellow fever virus. Some countries require a yellow fever vaccination certificate before entry from a country where the disease is common. People most at risk