Hyponatremia vasopressin receptor antagonists (vaptans), such as conivaptan, may be slightly more effective than fluid restriction in those with high volume or normal volume hyponatremia. They should not be used in people with low volume. Their use in SIADH is unclear. Demeclocycline, while sometimes used for SIADH, has significant side effects including potential kidney problems and sun sensitivity. In many people it has no benefit while in others it can result in overcorrection and high blood sodium levels. Daily use of urea by mouth, while not commonly used due to the taste, has tentative evidence in SIADH. It, however, is not
Antireticular cytotoxic serum Antireticular cytotoxic serum Anti-reticular Cytotoxic Serum is made from the blood of a rabbit that has been injected with homogenized cadaver spleen and rib marrow. In small quantities it can aid animal growth, but is toxic in large doses. It was first developed by Alexander A. Bogomolets in 1936. "It was a "miracle" that Professor Bogomolets made dying people walk with blood of cadavers circulating through their bodies, or hoped to extend our life-span for 150 years with the help of the A.C.S serum" - Red Miracle: The Story of Soviet Medicine by Edward Podolsky "World Book Encyclopedia", 1967 Edition,