Irvine Welsh His first novel, "Trainspotting", was published in 1993. Set in the mid-1980s, it uses a series of loosely connected short stories to tell the story of a group of characters tied together by decaying friendships, heroin addiction and stabs at escape from the oppressive boredom and brutality of their lives in the housing schemes. It was released to shock and outrage in some circles and great acclaim in others; "Time Out" called it "funny, unflinchingly abrasive, authentic and inventive", and "The Sunday Times" called Welsh "the best thing that has happened to British writing for decades". It was adapted as
Heroin users, compared to morphine, reportedly stems from its perceived different effects. Short-term addiction studies by the same researchers demonstrated that tolerance developed at a similar rate to both heroin and morphine. When compared to the opioids hydromorphone, fentanyl, oxycodone, and pethidine (meperidine), former addicts showed a strong preference for heroin and morphine, suggesting that heroin and morphine are particularly susceptible to abuse and addiction. Morphine and heroin were also much more likely to produce euphoria and other positive subjective effects when compared to these other opioids. In the United States, heroin is not accepted as medically useful. Under the generic