Ewan McGregor Collar" (1993). Not long afterwards, he starred in the BBC adaptation of "Scarlet and Black" (also 1993) with a young Rachel Weisz, and made his film debut in Bill Forsyth's "Being Human" (1994). For his role in the thriller "Shallow Grave" (also 1994), he won an Empire Award. The film was his first collaboration with director Danny Boyle. His international breakthrough followed with the role of heroin addict Mark Renton in Boyle's "Trainspotting" (1996), an adaptation of Irvine Welsh's novel of the same name. McGregor played the male romantic lead role in the British film "Little Voice" (1998). He was
Heroin users, compared to morphine, reportedly stems from its perceived different effects. Short-term addiction studies by the same researchers demonstrated that tolerance developed at a similar rate to both heroin and morphine. When compared to the opioids hydromorphone, fentanyl, oxycodone, and pethidine (meperidine), former addicts showed a strong preference for heroin and morphine, suggesting that heroin and morphine are particularly susceptible to abuse and addiction. Morphine and heroin were also much more likely to produce euphoria and other positive subjective effects when compared to these other opioids. In the United States, heroin is not accepted as medically useful. Under the generic