Tempranillo blanco La Rioja province of northern Spain. While Tempranillo is a dark-skin variety used to produce red wine, the grower discovered that one of his vines had undergone a mutation that produced yellow-green clusters after veraison. In the 21st century, the University of La Rioja and the Agricultural Research and Development Centre (CIDA) worked with local wineries (such as Viña Ijalba) to help revive and establish native grape varieties such as Tempranillo. Currently Tempranillo blanco is found only in the Rioja wine region of Spain. In 2007, the Spanish Institute for Foreign Trade working with the "Consejo Regulador" of the Rioja
Petite mutation be induced using a variety of mutagens, including DNA intercalating agents, as well as chemicals that can interfere with DNA synthesis in growing cells. Mutagens that create Petites are implicated in increased rates of degenerative diseases and in the aging process. A mutation that produces small (petite" > petite) anaerobic-like colonies had shown first in Yeast Saccharomyces cerevisiae and described by Boris Ephrussi and his co-workers in 1949 in Gif-sur-Yvette, France. The cells of petite colonies were smaller than those of wild-type colonies, but the term “petite” refers only to colony size and not the individual cell size. Over 50