Base (chemistry) increase the hydronium (HO) concentration in water, whereas bases reduce this concentration. A reaction between an acid and base is called neutralization. In a neutralization reaction, an aqueous solution of a base reacts with an aqueous solution of an acid to produce a solution of water and salt in which the salt separates into its component ions. If the aqueous solution is saturated with a given salt solute, any additional such salt precipitates out of the solution. The notion of a base as a concept in chemistry was first introduced by the French chemist Guillaume François Rouelle in 1754. He
Brefeldin A studying membrane traffic and [[Vesicle (biology and chemistry)|vesicle]] transport dynamics between the endoplasmic reticulum and Golgi apparatus. Brefeldin A is found naturally as a white to off-white [[crystal]]line solid. It forms a clear colorless solution when dissolved. It is soluble in [[methanol]] (10 mg/mL), [[ethanol]] (5 mg/mL), [[Dimethyl sulfoxide|DMSO]] (20 mg/mL), [[acetone]], and [[ethyl acetate]] (1 mg/mL) without the aid of heating. It is poorly soluble in water (slightly [[Miscibility|miscible]]). It is sold commercially with a purity of 98% or greater. It is recommended that it be stored desiccate at -20 °C away from direct sunlight. Its suggested shelf life