Gas-phase ion chemistry Gas-phase ion chemistry Gas phase ion chemistry is a field of science encompassed within both chemistry and physics. It is the science that studies ions and molecules in the gas phase, most often enabled by some form of mass spectrometry. By far the most important applications for this science is in studying the thermodynamics and kinetics of reactions. For example, one application is in studying the thermodynamics of the solvation of ions. Ions with small solvation spheres of 1, 2, 3... solvent molecules can be studied in the gas phase and then extrapolated to bulk solution. Transition state theory is
Phomoxanthone A PXA and PXB were discovered in 2001, and their preparation by isolation from "Phomopsis" fungal cultures was described in the corresponding publication. Briefly, a MeOH extract of a "Phomopsis" culture is mixed with HO and washed with hexane. The aqueous phase is then dried and the residue is dissolved in EtOAc, washed with HO, concentrated and repeatedly purified by size-exclusion chromatography. The resulting mixture of PXA and PXB is separated by HPLC. A modified method, in which the initial extraction is done with EtOAc instead of MeOH and the drying step is skipped, was described in 2013. Phomoxanthone A was