Yellow fever In 1873, Shreveport, Louisiana lost 759 citizens in an 80-day period to a Yellow fever epidemic, with over 400 additional victims eventually succumbing. The total death toll from August through November was approximately 1,200, In 1878, about 20,000 people died in a widespread epidemic in the Mississippi River Valley. That year, Memphis had an unusually large amount of rain, which led to an increase in the mosquito population. The result was a huge epidemic of yellow fever. The steamship "John D. Porter" took people fleeing Memphis northward in hopes of escaping the disease, but passengers were not allowed to disembark
Yellow fever vaccine shortages in vaccine supplies. Demand for yellow vaccine for preventive campaigns has increased from about 5 million doses per year to a projected 62 million per year by 2014. UNICEF reported in 2013 that supplies were insufficient. Manufacturers are producing about 35 million of the 64 million doses needed per year. Demand for the yellow fever vaccine has continued to increase due to the growing number of countries implementing yellow fever vaccination as part of their routine immunization programmes. Recent upsurges in yellow fever outbreaks in Angola (2015), Democratic Republic of Congo (2016), Uganda (2016), and more recently in Nigeria