Hypotonic hyponatremia Hypotonic hyponatremia Hypoosmolar hyponatremia is a condition where hyponatremia associated with a low plasma osmolality. The term "hypotonic hyponatremia" is also sometimes used. When the plasma osmolarity is low, the extracellular fluid volume status may be in one of three states: low volume, normal volume, or high volume. Loss of water is accompanied by loss of sodium. Treat underlying cause and give IV isotonic saline. It is important to note that sudden restoration of blood volume to normal will turn off the stimulus for continued ADH secretion. Hence, a prompt water diuresis will occur. This can cause a sudden and
Serum-separating tube Serum-separating tube Serum-separating tubes, also known as serum separator tubes or SSTs, are used in medical clinical chemistry tests requiring blood serum. SSTs are sometimes called "marble-top tubes," "tiger-tops," or "gold-topped tubes", referring to the stoppers which are either gold, red with a gold ring on top, or marbled red and grey. Marble-top tubes are also referred to as "tiger-tops" in some clinics. SPS tubes have a paler colour, sometimes leading confusion; these are known as "yellow tops" not "gold". Trademarked versions include Covidien "Corvac" tubes. They contain a special gel that separates blood cells from serum, as well as