Human digestive system digestive system is subject to a wide range of disorders many of which can be congenital. Mouth diseases can also be caused by pathogenic bacteria, viruses, fungi and as a side effect of some medications. Mouth diseases include tongue diseases and salivary gland diseases. A common gum disease in the mouth is gingivitis which is caused by bacteria in plaque. The most common viral infection of the mouth is gingivostomatitis caused by herpes simplex. A common fungal infection is candidiasis commonly known as "thrush" which affects the mucous membranes of the mouth. There are a number of esophageal diseases such
Human disease network Human disease network A human disease network is a network of human disorders and diseases with reference to their genetic origins or other features. More specifically, it is the map of human disease associations referring mostly to disease genes. For example, in a human disease network, two diseases are linked if they share at least one associated gene. A typical human disease network usually derives from bipartite networks which consist of both diseases and genes information. Additionally, some human disease networks use other features such as symptoms and proteins to associate diseases. In 2007, Goh et al. constructed a disease-gene