Economic importance of bacteria are used, too, to form organic acids in pickles and vinegar. Biotechnology bacteria the use of microorganisms including bacteria and fungi in the manufacturing and services industries. These include chemical manufacturing such as ethanol, acetone, organic acid, enzymes, and perfumes. In the chemical industry, bacteria are most important in the production of pharmaceuticals. "Escherichia coli" is used for commercial preparation of riboflavin and vitamin K. Genetic engineering is the manipulation of genes. It is also called recombinant DNA technology. In genetic engineering, pieces of DNA (genes) are introduced into a host by a variety of techniques, one of the earliest
Bacteria using genetic techniques such as guanine cytosine ratio determination, genome-genome hybridisation, as well as sequencing genes that have not undergone extensive lateral gene transfer, such as the rRNA gene. Classification of bacteria is determined by publication in the International Journal of Systematic Bacteriology, and Bergey's Manual of Systematic Bacteriology. The International Committee on Systematic Bacteriology (ICSB) maintains international rules for the naming of bacteria and taxonomic categories and for the ranking of them in the International Code of Nomenclature of Bacteria. The term "bacteria" was traditionally applied to all microscopic, single-cell prokaryotes. However, molecular systematics showed prokaryotic life to consist