Mydriasis eye, and also to reduce painful ciliary muscle spasm (see cycloplegia). One effect of administration of a mydriatic is intolerance to bright light (photophobia). Purposefully-induced mydriasis via mydriatics is also used as a diagnostic test for Horner's syndrome. Mydriasis can be induced via modulation of adrenergic or cholinergic signalling. Within the adrenergic system, norepinephrine is a hormone and neurotransmitter responsible for regulating physiological processes in the body, including the involuntary muscles of the autonomic nervous system (such as the dilation or constriction of the pupil aperture via the muscles of the iris). Modulation of norepinephrine signalling can induce mydriasis. For
What a piece of work is a man What a piece of work is a man "What a piece of work is man!" is a phrase within a soliloquy by Prince Hamlet in William Shakespeare's play of the same name. Hamlet is reflecting, at first admiringly, and then despairingly, on the human condition. The soliloquy, spoken in the play by Prince Hamlet to Rosencrantz and Guildenstern in Act II, Scene 2, follows in its entirety. Rather than appearing in blank verse, the typical mode of composition of Shakespeare's plays, the speech appears in straight prose: Hamlet is saying that although humans may appear to think and act "nobly"