Mydriasis eye, and also to reduce painful ciliary muscle spasm (see cycloplegia). One effect of administration of a mydriatic is intolerance to bright light (photophobia). Purposefully-induced mydriasis via mydriatics is also used as a diagnostic test for Horner's syndrome. Mydriasis can be induced via modulation of adrenergic or cholinergic signalling. Within the adrenergic system, norepinephrine is a hormone and neurotransmitter responsible for regulating physiological processes in the body, including the involuntary muscles of the autonomic nervous system (such as the dilation or constriction of the pupil aperture via the muscles of the iris). Modulation of norepinephrine signalling can induce mydriasis. For
What a Pleasure Stakes What a Pleasure Stakes The What a Pleasure Stakes is an American flat Thoroughbred horse race for two-year-olds held annually at Calder Race Course in Miami Gardens, Florida. It is currently an ungraded stakes race run over a distance of 8.5 furlongs on dirt. The race has traditionally been held during the Tropical at Calder meet, from late October through early January. This meet normally has some of the strongest stakes programs of Calder’s eight-month season. Due to permit disputes with Hialeah Park Race Track, the race was pushed back in 1987 and 1991 into the following year. Both of