Pupillary response Pupillary response Pupillary response is a physiological response that varies the size of the pupil, via the optic and oculomotor cranial nerve. A constriction response (miosis), is the narrowing of the pupil, which may be caused by scleral buckles or drugs such as opiates/opioids or anti hypertension medications. Constriction of the pupil occurs when the circular muscle, controlled by the parasympathetic nervous system (PSNS), contracts. A dilation response (mydriasis), is the widening of the pupil and may be caused by adrenaline, anticholinergic agents or drugs such as MDMA, cocaine, amphetamines and some hallucinogenics. Dilation of the pupil occurs when the
The Widening Gyre (novel) The Widening Gyre (novel) The Widening Gyre is a 1983 novel by Robert B. Parker, featuring his private detective character Spenser. The title comes from the first line of W.B. Yeats poem "The Second Coming". Spenser is hired to head up the security detail for Congressman Meade Alexander as he runs for the Senate. The congressman confides to Spenser that he is being blackmailed by someone who wants him to drop out of the senate race. The congressman's wife Ronni drinks too much and there is an explicit sex tape of her and a much younger man. Spenser's assignment is