Osmotherapy inhibits these channels. Vasopressin receptors activated by vasopressin are found on the basolateral membrane of the cells lining the collecting ducts of the kidneys. Aneurysmal subarachnoid hemorrhage(aSAH) results in hyponatremia which leads to water retention and antidiuretic hormone release causing increase in intracranial pressure and formation of cerebral edema. This can be prevented by administration of conivaptan, a safe FDA approved drug that treats euvolemic hyponatremia. Through the process of aquaresis, conivapten which is a vasopressin receptor antagonist improves serum sodium concentration while eliminating free water without having any negative effect on systolic blood pressure and pulse rate. Since it
Blood libel Blood libel Blood libel (also blood accusation) is an antisemitic canard accusing Jews of kidnapping and murdering the children of Christians in order to use their blood as part of religious rituals. Historically, these claims—alongside those of well poisoning and host desecration—have been a major theme of the persecution of Jews in Europe. Blood libels typically say that Jews require human blood for the baking of matzos for Passover, although this element was allegedly absent in the earliest cases which claimed that then-contemporary Jews reenacted the crucifixion. The accusations often assert that the blood of the children of Christians is