Apamin therapeutic effect on Parkinson's disease. Dopamine, which is depleted in this disease, will be released from midbrain dopaminergic neurons when these SK channels are inhibited. SK channels have also been proposed as targets for the treatment of epilepsy, emotional disorders and schizophrenia. Apamin Apamin is an 18 amino acid peptide neurotoxin found in apitoxin (bee venom). Dry bee venom consists of 2–3% of apamin. Apamin selectively blocks SK channels, a type of Ca-activated K channel expressed in the central nervous system. Toxicity is caused by only a few amino acids, these are cysteine, lysine, arginine, arginine and histidine. These amino
The Venom Business The Venom Business The Venom Business is Michael Crichton's seventh published novel. It was released in 1969 by The World Publishing Company (New York) under the pseudonym of John Lange. It was the first hard cover book from Lange. Hard Case Crime republished the novel under Crichton's name on November 19, 2013. Charles Raynaud is a smuggler and he is very content and mildly successful with what he does for a living. Based in Mexico, Charles uses his exceptional skill as a snake handler to his advantage by "exporting" snakes out of Mexico under the guise of medical research—their venom