Mydriasis eye, and also to reduce painful ciliary muscle spasm (see cycloplegia). One effect of administration of a mydriatic is intolerance to bright light (photophobia). Purposefully-induced mydriasis via mydriatics is also used as a diagnostic test for Horner's syndrome. Mydriasis can be induced via modulation of adrenergic or cholinergic signalling. Within the adrenergic system, norepinephrine is a hormone and neurotransmitter responsible for regulating physiological processes in the body, including the involuntary muscles of the autonomic nervous system (such as the dilation or constriction of the pupil aperture via the muscles of the iris). Modulation of norepinephrine signalling can induce mydriasis. For
What Is History? and were instead products of their own places and times, which in turn decided what "facts of the past" they determined into "facts of history". British historian Richard J. Evans said "What Is History?" caused a revolution in British historiography in the 1960s. Australian historian Keith Windschuttle, a critic of Carr, said "What Is History?" is one of the most influential books written about historiography, and that very few historians working in the English language since the 1960s had not read it. What Is History? What Is History? is a study that was written by the English historian E. H.