Yellow fever Because of this sylvatic cycle, yellow fever cannot be eradicated except by eradicating the mosquitoes that serve as vectors. In Africa, a third infectious cycle known as "savannah cycle" or intermediate cycle, occurs between the jungle and urban cycles. Different mosquitoes of the genus "Aedes" are involved. In recent years, this has been the most common form of transmission of yellow fever in Africa. Concern exists about yellow fever spreading to southeast Asia, where its vector "A. aegypti" already occurs. After transmission from a mosquito, the viruses replicate in the lymph nodes and infect dendritic cells in particular. From there,
1793 Philadelphia yellow fever epidemic was also advocated by Dr. Edward Stevens, who in mid-September claimed it had cured Alexander Hamilton, Secretary of the Treasury, of the fever. Rush searched the medical literature for other approaches. Benjamin Franklin had given him letters sent by Dr. John Mitchell, related to treating patients during a 1741 yellow fever outbreak in Virginia. (Franklin never published the letters.) Mitchell noted that the stomach and intestines filled with blood and that these organs had to be emptied at all costs. "On this account," Mitchell argued, "an ill-timed scrupulousness about the weakness of the body is of bad consequences in these