Glycogen storage disease type I as fat. When digestion of a meal is complete, insulin levels fall, and enzyme systems in the liver cells begin to remove glucose molecules from strands of glycogen in the form of G6P. This process is termed glycogenolysis. The G6P remains within the liver cell unless the phosphate is cleaved by glucose-6-phosphatase. This dephosphorylation reaction produces free glucose and free anions. The free glucose molecules can be transported out of the liver cells into the blood to maintain an adequate supply of glucose to the brain and other organs of the body. Glycogenolysis can supply the glucose needs of an
Human brain and large elaborate network systems such as the salience network and the default mode network, and the activity between them is driven by the process of neurotransmission. The brain consumes up to 20% of the energy used by the human body, more than any other organ. In humans, blood glucose is the primary source of energy for most cells and is critical for normal function in a number of tissues, including the brain. The human brain consumes approximately 60% of blood glucose in fasted, sedentary individuals. Brain metabolism normally relies upon blood glucose as an energy source, but during times