Mydriasis eye, and also to reduce painful ciliary muscle spasm (see cycloplegia). One effect of administration of a mydriatic is intolerance to bright light (photophobia). Purposefully-induced mydriasis via mydriatics is also used as a diagnostic test for Horner's syndrome. Mydriasis can be induced via modulation of adrenergic or cholinergic signalling. Within the adrenergic system, norepinephrine is a hormone and neurotransmitter responsible for regulating physiological processes in the body, including the involuntary muscles of the autonomic nervous system (such as the dilation or constriction of the pupil aperture via the muscles of the iris). Modulation of norepinephrine signalling can induce mydriasis. For
Batman: The Widening Gyre it makes a unique “ka-klack” sound. Wayne hears someone behind him mimic the “ka-klack” sound. A horrified Batman turns around to discover that Baphomet is, in fact, the villain Onomatopoeia. The book ends on a cliffhanger, as Onomatopoeia begins to slit Silver St. Cloud's throat. "Batman: The Widening Gyre" received mixed reviews from critics, as many felt that Smith's trademark brand of crude humor felt out-of-place in a "Batman" comic. Particular criticism was directed at a scene where Batman confesses to Baphomet that, during , he misjudged the power of some explosives he was using, and the resulting blast of