Hyponatremia feedback loop is overwhelmed by increased fluid intake, 2) the feedback loop malfunctions such that ADH is always "turned on"; 3) the receptors in the kidney are always "open" regardless of there being no signal from ADH to be open; or 4) there is an increased ADH even though there is no normal stimulus (elevated serum sodium) for ADH to be increased. Hyponatremia occurs in one of two ways: either the osmoreceptor-aquaporin feedback loop is "overwhelmed", or it is "interrupted". If it is interrupted, it is either "related" or "not related" to ADH. If the feedback system is overwhelmed, this
Human Element Robotoki was shut down on January 20, 2015 due to lack of publishing deal of the premium version of the game and the inability of the founder of the company to self-fund the development of the game. The game is currently on hiatus. Human Element Human Element was an online multiplayer video game under development by Robotoki for Microsoft Windows, PlayStation 4, and Xbox One. Development was halted when the studio was closed as indicated by a farewell message on Robotoki's (now defunct) blog on January 20, 2015, by the studio's founder, Robert Bowling. "Human Element" is the first game