Sievert Nuclear Regulatory Commission permits the use of the units curie, rad, and rem alongside SI units, the European Union European units of measurement directives required that their use for "public health ... purposes" be phased out by 31 December 1985. An older unit for the dose equivalent is the rem, still often used in the United States. One sievert is equal to 100 rem: Sievert The sievert (symbol: Sv) is a derived unit of ionizing radiation dose in the International System of Units (SI) and is a measure of the health effect of low levels of ionizing radiation on the
Biological effects of radiation on the epigenome in LINE1 protein levels. Increased transcription of LINE1 transposable elements results in greater mobilization of the LINE1 loci and therefore increases genomic instability. Irradiated cells can be linked to a variety of histone modifications. Ionizing radiation in breast cancer cell inhibits H4 lysine tri-methylation. Mouse models exposed to high levels of X-ray irradiation exhibited a decrease in both the tri-methylation of H4-Lys20 and the compaction of the chromatin. With the loss of tri-methylation of H4-Lys20, DNA hypomethylation increased resulting in DNA damage and increased genomic instability. Breaks in DNA due to ionizing radiation can be repaired. New DNA synthesis by