Apamin Apamin Apamin is an 18 amino acid peptide neurotoxin found in apitoxin (bee venom). Dry bee venom consists of 2–3% of apamin. Apamin selectively blocks SK channels, a type of Ca-activated K channel expressed in the central nervous system. Toxicity is caused by only a few amino acids, these are cysteine, lysine, arginine, arginine and histidine. These amino acids are involved in the binding of apamin to the Ca-activated K channel. Due to its specificity for SK channels, apamin is used as a drug in biomedical research to study the electrical properties of SK channels and their role in the
Block sort Block sort Block sort, or block merge sort, is a sorting algorithm combining at least two merge operations with an insertion sort to arrive at in-place stable sorting. It gets its name from the observation that merging two sorted lists, and , is equivalent to breaking into evenly sized "blocks", inserting each block into under special rules, and merging pairs. One practical algorithm for O(log n) in place merging was proposed by Pok-Son Kim and Arne Kutzner in 2008. The outer loop of block sort is identical to a bottom-up merge sort, where each "level" of the sort merges pairs