Homogeneous and heterogeneous mixtures mixture is air. In physical chemistry and materials science this refers to substances and mixtures which are in a single phase. This is in contrast to a substance that is heterogeneous. A solution has been a special type of homogeneous mixture. Solutions are homogeneous because the ratio of solute to solvent remains the same throughout the solution even if homogenized with multiple sources, and stable because the solute will not settle out after any period of time, and it cannot be removed by a filter or by centrifuge. This type of mixture is very stable, i.e., its particles do not
Phomoxanthone A PXA and PXB were discovered in 2001, and their preparation by isolation from "Phomopsis" fungal cultures was described in the corresponding publication. Briefly, a MeOH extract of a "Phomopsis" culture is mixed with HO and washed with hexane. The aqueous phase is then dried and the residue is dissolved in EtOAc, washed with HO, concentrated and repeatedly purified by size-exclusion chromatography. The resulting mixture of PXA and PXB is separated by HPLC. A modified method, in which the initial extraction is done with EtOAc instead of MeOH and the drying step is skipped, was described in 2013. Phomoxanthone A was