2016 Angola and DR Congo yellow fever outbreak a 32-year-old male Chinese citizen who had been in Angola had developed yellow fever on return. The case was the first imported yellow fever case in China in history. Yellow fever has never appeared in Asia even though the mosquito vector is present. Additional cases were later reported in people who first had symptoms while in Luanda. ProMED-mail moderator Jack Woodall warned that "spread could make the Ebola and Zika epidemics look like picnics in the park!" and that "international action should start now." Chinese authorities strengthened thermal imaging at airports to detect passengers with elevated body temperatures. A Chinese
Yellow fever serves as a molecular signal to stall the exonuclease and is the only viral requirement for subgenomic flavivirus RNA (sfRNA) production. The sfRNAs are a result of incomplete degradation of the viral genome by the exonuclease and are important for viral pathogenicity. Yellow fever belongs to the group of hemorrhagic fevers. The viruses infect, amongst others, monocytes, macrophages, and dendritic cells. They attach to the cell surface via specific receptors and are taken up by an endosomal vesicle. Inside the endosome, the decreased pH induces the fusion of the endosomal membrane with the virus envelope. The capsid enters the cytosol,