Yellow fever the introduction of sugar plantations created the conditions for mosquito and viral reproduction, and subsequent outbreaks of yellow fever. Deforestation reduced populations of insectivorous birds and other creatures that fed on mosquitoes and their eggs. Although yellow fever is most prevalent in tropical-like climates, the northern United States were not exempted from the fever. The first outbreak in English-speaking North America occurred in New York City in 1668, and a serious one afflicted Philadelphia in 1793. English colonists in Philadelphia and the French in the Mississippi River Valley recorded major outbreaks in 1669, as well as those occurring later in
Yellow Fever Commission Yellow Fever Commission The Yellow Fever Commission was a research team of the United States Army which researched treatment for yellow fever. The research process itself became a focus of study for later generations. A United States nurse named Clara Maass and two Spanish immigrants were among those who died as a result of their research participation. Researchers mark the research of the Yellow Fever Commission as the origin of the model of modern consent in medical research. The 1934 play "Yellow Jack" told the story of Walter Reed in the Yellow Fever Commission. That play was the basis of