Gamay The grape brought relief to the village growers following the decline of the Black Death. In contrast to the Pinot noir variety, Gamay ripened two weeks earlier and was less difficult to cultivate. It also produced a strong, fruitier wine in a much larger abundance. In July 1395, the Duke of Burgundy Philippe the Bold outlawed the cultivation of the grape, referring to it as the ""disloyal Gaamez"" that in spite of its ability to grow in abundance was full of ""very great and horrible harshness"", due in part to the variety's occupation of land that could be used for
Petite mutation be induced using a variety of mutagens, including DNA intercalating agents, as well as chemicals that can interfere with DNA synthesis in growing cells. Mutagens that create Petites are implicated in increased rates of degenerative diseases and in the aging process. A mutation that produces small (petite" > petite) anaerobic-like colonies had shown first in Yeast Saccharomyces cerevisiae and described by Boris Ephrussi and his co-workers in 1949 in Gif-sur-Yvette, France. The cells of petite colonies were smaller than those of wild-type colonies, but the term “petite” refers only to colony size and not the individual cell size. Over 50