Immunoglobulin A only weakly. IgA exists in two isotypes, IgA1 and IgA2. They are both heavily glycosylated proteins. While IgA1 predominates in serum (~80%), IgA2 percentages are higher in secretions than in serum (~35% in secretions); the ratio of IgA1 and IgA2 secreting cells varies in the different lymphoid tissues of the human body: Both IgA1 and IgA2 have been found in external secretions like colostrum, maternal milk, tears and saliva, where IgA2 is more prominent than in the blood. Polysaccharide antigens tend to induce more IgA2 than protein antigens. Both IgA1 and IgA2 can be in membrane-bound form. ("see B-cell receptor")
Happiness is a cigar called Hamlet ITV list made in 2005 and as the third funniest television advertisement ever by Campaign Live in 2008. Happiness is a cigar called Hamlet "Happiness is a cigar called Hamlet" is one of the best remembered British advertising campaigns for a tobacco product. It was a long-running campaign for Hamlet Cigars, lasting on television until all tobacco advertising on television was banned in the UK in 1991. They returned in cinemas in 1996, continuing there until 1999, with the final commemorative advert and the modified tagline, "Happiness will always be a cigar called Hamlet." Commercials used an excerpt from a