Ewan McGregor Collar" (1993). Not long afterwards, he starred in the BBC adaptation of "Scarlet and Black" (also 1993) with a young Rachel Weisz, and made his film debut in Bill Forsyth's "Being Human" (1994). For his role in the thriller "Shallow Grave" (also 1994), he won an Empire Award. The film was his first collaboration with director Danny Boyle. His international breakthrough followed with the role of heroin addict Mark Renton in Boyle's "Trainspotting" (1996), an adaptation of Irvine Welsh's novel of the same name. McGregor played the male romantic lead role in the British film "Little Voice" (1998). He was
Heroin Regulations", and the "Food and Drug Regulations", to allow doctors to prescribe diamorphine to people who have a severe opioid addiction who have not responded to other treatments. The prescription heroin can be accessed by doctors through Health Canada's Special Access Programme (SAP) for "emergency access to drugs for patients with serious or life-threatening conditions when conventional treatments have failed, are unsuitable, or are unavailable." The onset of heroin's effects depends upon the route of administration. Studies have shown that the subjective pleasure of drug use (the reinforcing component of addiction) is proportional to the rate at which the blood