History of yellow fever as a result of the numerous deaths, of the French company licensed to build the canal resulted in a massive financial crisis in France. History of yellow fever The evolutionary origins of yellow fever most likely lie in Africa. Phylogenetic analyses indicate that the virus originated from East or Central Africa, with transmission between primates and humans, and spread from there to West Africa. The virus as well as the vector "Aedes aegypti", a mosquito species, were probably brought to the western hemisphere and the Americas by slave trade ships from Africa after the first European exploration in 1492. The
1793 Philadelphia yellow fever epidemic atmosphere that might last 50 years and make deadly epidemics almost certain. Yellow fever epidemics became seen as a national crisis. When in 1855 a French doctor published an 813-page history of yellow fever in Philadelphia, covering outbreaks from 1699 to 1854, he devoted only a few pages to the 1793 epidemic. General 20th-century US histories, such as the 10-volume "Great Epochs in American History," published in 1912, used short excerpts from Carey's account. The first history of the epidemic to draw on more primary sources was J. H. Powell's "Bring Out Your Dead" (1949), but he did not use