Exercise-associated hyponatremia cells in one area begin to increase in size, swelling occurs in the affected area. Swelling is commonly observed in hands, legs, and feet. Sodium is also important in regulating the amount of water that passes through the blood-brain barrier. Decreased sodium blood levels result in increased permeability of water across the blood-brain barrier. This increased influx of water causes brain swelling which leads to severe neurological symptoms. EAH is categorized by having a blood serum or plasma sodium level below normal, which is less than 135 mmol/l. Asymptomatic EAH is not normally detected unless the athlete has had a
Autologous conditioned serum the procedure performed by Wehling, is one famous case based on his recovery from his previously poor knees.Some basketball fans refer to the procedure as the "Kobe Procedure". The procedure cost €6,000 (about $7,400) as of July 2012. The treatment is not covered by health insurance. Autologous conditioned serum Autologous conditioned serum, also known as Orthokine and Regenokine, is an experimental procedure in which a person's own blood is extracted, manipulated, and then reintroduced with claims benefit in osteoarthritis. There is limited evidence on safety and effectiveness as of 2017. It is not included in medical guidelines as of 2017.