Sacrum The number of sacral vertebrae varies slightly. For instance, the S1S5 vertebrae of a horse will fuse, the S1S3 of a dog will fuse, and four pelvic vertebrae of a rat will fuse between the lumbar and the caudal vertebrae of its tail. The "Stegosaurus" dinosaur had a greatly enlarged neural canal in the sacrum, characterized as a "posterior brain case”. The sacrum is a complex structure providing support for the spine and accommodation for the spinal nerves. It also articulates with the hip bones. The sacrum has a base, an apex, and three surfaces – a pelvic, dorsal and
Bone resorption in the resorption process. High levels of calcium, magnesium, phosphate and products of collagen will be released into the extracellular fluid as the osteoclasts tunnel into the mineralized bone. Osteoclasts are prominent in the tissue destruction found in psoriatic arthritis and rheumatological disorders. The human body is in a constant state of bone remodeling. Bone remodelling is a process which maintains bone strength and ion homeostasis by replacing discrete parts of old bone with newly synthesized packets of proteinaceous matrix. Bone is resorbed by osteoclasts, and is deposited by osteoblasts in a process called ossification. Osteocyte activity plays a key