Sievert Nuclear Regulatory Commission permits the use of the units curie, rad, and rem alongside SI units, the European Union European units of measurement directives required that their use for "public health ... purposes" be phased out by 31 December 1985. An older unit for the dose equivalent is the rem, still often used in the United States. One sievert is equal to 100 rem: Sievert The sievert (symbol: Sv) is a derived unit of ionizing radiation dose in the International System of Units (SI) and is a measure of the health effect of low levels of ionizing radiation on the
Biological effects of radiation on the epigenome the normal development of the brain. DNA methylation influences tissue responses to ionizing radiation. Modulation of methylation in the gene MGMT or in transposable elements such as LINE1 could be used to alter tissue responses to ionizing radiation and potentially opening new areas for cancer treatment. MGMT serves as a prognostic marker in glioblastoma. Hypermethylation of MGMT is associated with the regression of tumors. Hypermethylation of MGMT silences its transcription inhibiting alkylating agents in tumor killing cells. Studies have shown patients who received radiotherapy, but no chemotherapy after tumor extraction, had an improved response to radiotherapy due to the methylation