Ewan McGregor Collar" (1993). Not long afterwards, he starred in the BBC adaptation of "Scarlet and Black" (also 1993) with a young Rachel Weisz, and made his film debut in Bill Forsyth's "Being Human" (1994). For his role in the thriller "Shallow Grave" (also 1994), he won an Empire Award. The film was his first collaboration with director Danny Boyle. His international breakthrough followed with the role of heroin addict Mark Renton in Boyle's "Trainspotting" (1996), an adaptation of Irvine Welsh's novel of the same name. McGregor played the male romantic lead role in the British film "Little Voice" (1998). He was
Heroin continues to be widely used in palliative care in the UK, where it is commonly given by the subcutaneous route, often via a syringe driver, if patients cannot easily swallow morphine solution. The advantage of diamorphine over morphine is that diamorphine is more fat soluble and therefore more potent by injection, so smaller doses of it are needed for the same effect on pain. Both of these factors are advantageous if giving high doses of opioids via the subcutaneous route, which is often necessary in palliative care. A number of European countries prescribe heroin for treatment of heroin addiction. Diamorphine