Economic importance of bacteria are used, too, to form organic acids in pickles and vinegar. Biotechnology bacteria the use of microorganisms including bacteria and fungi in the manufacturing and services industries. These include chemical manufacturing such as ethanol, acetone, organic acid, enzymes, and perfumes. In the chemical industry, bacteria are most important in the production of pharmaceuticals. "Escherichia coli" is used for commercial preparation of riboflavin and vitamin K. Genetic engineering is the manipulation of genes. It is also called recombinant DNA technology. In genetic engineering, pieces of DNA (genes) are introduced into a host by a variety of techniques, one of the earliest
Bacteria made during the replication of DNA or from exposure to mutagens. Mutation rates vary widely among different species of bacteria and even among different clones of a single species of bacteria. Genetic changes in bacterial genomes come from either random mutation during replication or "stress-directed mutation", where genes involved in a particular growth-limiting process have an increased mutation rate. Some bacteria also transfer genetic material between cells. This can occur in three main ways. First, bacteria can take up exogenous DNA from their environment, in a process called transformation. Many bacteria can naturally take up DNA from the environment, while