Broad-spectrum antibiotic estimated 10-100 trillion multiple organisms that colonize the human body. As a side-effect of therapy, antibiotics can change the body's normal microbial content by attacking indiscriminately both the pathological and naturally occurring, beneficial or harmless bacteria found in the intestines, lungs and bladder. The destruction of the body's normal bacterial flora is thought to disrupt immunity, nutrition, and lead to a relative overgrowth in some bacteria or fungi. An overgrowth of drug-resistant microorganisms can lead to a secondary infection such as "Clostridium difficile" ("C. diff") or candidiasis ("thrush"). This side-effect is more likely with the use of broad-spectrum antibiotics, given
John Lightfoot (biologist) "Ryssus", but including also "Lichen" as "Algae Terrestres", terrestrial algae. Only nine genera of fungi are recognised in the book: "Agaricus", "Boletus", "Hydnum", "Phallus", "Helvella", "Peziza", "Clavaria", "Lycoperdon", and "Mucor" (listed on page 645); a tenth fungal genus, "Tremella" is covered, but included among his algae. "Scottish Fungi" note that "While his classification might be a bit wonky by today's understanding, most of the species he recorded can be traced to modern taxa", and that he provided the first British records for the chanterelle and the summer truffle. The book has an "English and Scotch Index of the Names of