Sodium in biology mEq/liter (135 - 145 mmol/L). A serum sodium level of less than 135 mEq/L qualifies as hyponatremia, which is considered severe when the serum sodium level is below 125 mEq/L. The renin–angiotensin system and the atrial natriuretic peptide indirectly regulate the amount of signal transduction in the human central nervous system, which depends on sodium ion motion across the nerve cell membrane, in all nerves. Sodium is thus important in neuron function and osmoregulation between cells and the extracellular fluid; the distribution of sodium ions are mediated in all animals by sodium–potassium pumps, which are active transporter solute pumps, pumping
Human Element engage and impact in the scenarios you will be presented with on a physical and moral level that you approach this world." The game was announced on June 1, 2012, and more details were released in the July edition of "Game Informer". On July 19, 2012, Robotoki's president Robert Bowling announced that "Human Element" would have an episodic prequel released exclusively on the Ouya, as a first-party title. But it was later announced that the studio decided to cancel the Ouya version of Human Element "very early on" and switch focus to the open-world experience on other more powerful platforms.