Transfer factor factors are contraindicated for women who are pregnant or breastfeeding. When human- and bovine-derived transfer factor are generated from blood cells they carry the potential for blood-borne disease such as HIV/AIDS and Hepatitis C. Colostrum is a form of milk produced by the mammary glands of mammals (including humans) in late pregnancy. Colostrum also contains multiple immune modulating molecules, including high antibody levels. Based on studies noting an overlap in the observed in vitro effects between a molecule contained in colostrum called colostrinin and the dialyzable leukocyte extract mentioned above, a hypothesis formed that the two were the same. There
Invariant of a binary form for the ring of covariants. showed that the ring of invariants of a degree 8 form is generated by 9 invariants of degrees 2, 3, 4, 5, 6, 7, 8, 9, 10, and the ring of covariants is generated by 69 covariants. August von Gall () and confirmed the generators for the ring of invariants and showed that the ideal of relations between them is generated by elements of degrees 16, 17, 18, 19, 20. showed that the algebra of invariants of a degree 9 form is generated by 92 invariants. Cröni, Hagedorn, and Brouwer computed 476 covariants, and Lercier