Toe pressure Toe pressure Blood pressure in toes can be measured using special equipment, and is often valuable in assessment of severe peripheral artery disease, in particular in patients with diabetes where measurement of ankle pressure / ABPI is often unreliable (because of local stiffening of arterial wall). Feet are often cold and to make sure measurement is not affected by local vasoconstriction, the patient's feet may be pre-warmed in water or by warm air to a skin temperature of around 30 °C. Measurement is done with the patient lying flat, with feet at heart level, using sphygmomanometry: the big toe is
Destroy All Humans! Big Willy Unleashed provided is downright terrible." Regarding its place in the game's series, IGN stated that "It’s still fun to go nuts with the anal probe gun, rip heads off of pedestrians with the giant arms of Big Willy, and chuckle at the campy VO". Destroy All Humans! Big Willy Unleashed Destroy All Humans! Big Willy Unleashed is an action-adventure video game developed by Locomotive Games and published by THQ for the Wii. A PlayStation 2 version was originally going to be released alongside the Wii, but was ultimately canceled because of budget cuts. A PlayStation Portable version was also canceled, due