Prospective Outlook on Long-term Energy Systems by a merit order that is based on marginal costs of operation, maintenance and annualized capital costs. Expected power demand over the year influences investment decisions for new capacity planning in the next step. The model includes accounting of greenhouse gas (GHG) emissions and allows visualising GHG flows on sectoral, regional and global levels. POLES covers fuel combustion-related emissions in all demand sectors, thus covering over half of global GHG emissions. The six Kyoto Protocol GHGs are covered (carbon dioxide, methane, nitrous oxide, sulphur hexafluoride, hydrofluorocarbons and perfluorocarbons). The model can be used to test the sensibility of the energy
Sulfur dioxide are mediated via ATP-dependent calcium channels and L-type ("dihydropyridine") calcium channels. Endogenous sulfur dioxide is also a potent antiinflammatory, antioxidant and cytoprotective agent. It lowers blood pressure and slows hypertensive remodeling of blood vessels, especially thickening of their intima. It also regulates lipid metabolism. Endogenous sulfur dioxide also diminishes myocardial damage, caused by isoproterenol adrenergic hyperstimulation, and strengthens the myocardial antioxidant defense reserve. Being easily condensed and possessing a high heat of evaporation, sulfur dioxide is a candidate material for refrigerants. Prior to the development of chlorofluorocarbons, sulfur dioxide was used as a refrigerant in home refrigerators. Sulfur dioxide is