Patent medicine the patent medicines, some of their makers began replacing the opium tincture laudanum with acetanilide, a particularly toxic non-steroidal anti-inflammatory drug with analgesic as well as antipyretic properties that had been introduced into medical practice under the name "Antifebrin" by A. Cahn and P. Hepp in 1886. But this ingredient change probably killed more of the nostrum's users than the original narcotics did, since acetanilide not only caused an alarming cyanosis due to methemoglobinemia but was later discovered to cause liver and kidney damage. The occasional reports of acetanilide-induced cyanosis prompted the search for supposedly less toxic aniline derivatives, such
An Old Fashioned Thanksgiving the day. This made Hallmark Channel rank #6 for the week. This made the film the fifth-highest-rated original movie in the network's history to its date, and its fourth-most-watched original movie among households. It is also the network's most watched and highest-rated November original movie ever. Critics' reviews, however, were mixed. "Star" magazine called the film "stuffy,", while the "TV Examiner" claimed "Hallmark Channel has cranked a sweet, ultimately uplifting old school holiday film" and called it an "old style of made-for-TV film." An Old Fashioned Thanksgiving An Old Fashioned Thanksgiving is a television film based on a short story