Metered-dose inhaler stringent set of criteria, they must: In the early days of MDIs the most commonly used propellants were the chlorofluorocarbons CFC-11, CFC-12 and CFC-114. In 2008 the Food and Drug Administration announced that inhalers using chlorofluorocarbons as a propellant, such as Primatene Mist, could no longer be manufactured or sold as of 2012. This followed from the U.S. decision to agree to the 1987 Montreal Protocol on Substances that Deplete the Ozone Layer. Phospholipids are important natural surfactant lipids used in enhancing penetration and bioavailability. Phospholipids act by reducing the high surface tension forces at the air-water interface within the
1987–88 Montreal Canadiens season four years in a row, sweeping the Bruins in three of the past four seasons, and beating them 3–2 in a best-of-five the other year. This time, the Bruins' defence would wear down Montreal, as Ken Linseman, Ray Bourque and Cam Neely provided the offence to finally conquer the Canadiens. It was the first Bruins' playoff series win over the Habs in 44 seasons. "Boston wins best-of-seven series 4–1" Montreal's draft picks at the 1987 NHL Entry Draft held at the Joe Louis Arena in Detroit, Michigan. 1987–88 Montreal Canadiens season The 1987–88 Montreal Canadiens season was the team's 79th