Acetonitrile formulations for nail polish remover, despite its toxicity. At least two cases have been reported of accidental poisoning of young children by acetonitrile-based nail polish remover, one of which was fatal. Acetone and ethyl acetate are often preferred as safer for domestic use, and acetonitrile has been banned in cosmetic products in the European Economic Area since March 2000. In common with other nitriles, acetonitrile can be metabolised in microsomes, especially in the liver, to produce hydrogen cyanide, as was first shown by Pozzani "et al." in 1959. The first step in this pathway is the oxidation of acetonitrile to
Nail art later) men in the 2000s brought to the males also the sensibility of taking care of their hands and nails. As David Beckham, demonstrating how a football player, a husband and a father could also take care of himself showed men that they could also invest money and time in appearance and still keep their masculinity. Before the metrosexual trend, the punk subculture also used the black nail polish in a “dirty” way to show how rebel they were against social rules, also the nail polish in a role of showing their disdain to any rules and meant to shock