Acetonitrile formulations for nail polish remover, despite its toxicity. At least two cases have been reported of accidental poisoning of young children by acetonitrile-based nail polish remover, one of which was fatal. Acetone and ethyl acetate are often preferred as safer for domestic use, and acetonitrile has been banned in cosmetic products in the European Economic Area since March 2000. In common with other nitriles, acetonitrile can be metabolised in microsomes, especially in the liver, to produce hydrogen cyanide, as was first shown by Pozzani "et al." in 1959. The first step in this pathway is the oxidation of acetonitrile to
PEAR team, versioning-control and documentation. A PEAR package is distributed as a gzipped tar file. Each archive consists of source code written in PHP, . Many PEAR packages can readily be used by developers as ordinary third party code via simple include statements in PHP. More elegantly, the PEAR package manager which comes with PHP by default may be used to install PEAR packages so that the extra functionality provided by the package appears as an integrated part of the PHP installation. Unlike the Comprehensive Perl Archive Network (CPAN) archives, , PEAR packages do not have implicit dependencies so that a