Period 6 element point of −38.83 °C and boiling point of 356.73 °C, mercury has one of the narrowest ranges of its liquid state of any metal. Mercury occurs in deposits throughout the world mostly as cinnabar (mercuric sulfide). The red pigment vermilion is mostly obtained by reduction from cinnabar. Cinnabar is highly toxic by ingestion or inhalation of the dust. Mercury poisoning can also result from exposure to water-soluble forms of mercury (such as mercuric chloride or methylmercury), inhalation of mercury vapor, or eating seafood contaminated with mercury. Mercury is used in thermometers, barometers, manometers, sphygmomanometers, float valves, mercury switches, and other
Substantial equivalence Substantial equivalence In food safety, the concept of substantial equivalence holds that the safety of a new food, particularly one that has been genetically modified (GM), may be assessed by comparing it with a similar traditional food that has proven safe in normal use over time. It was first formulated as a food safety policy in 1993, by the Organisation for Economic Co-operation and Development (OECD). As part of a food safety testing process, substantial equivalence is the initial step, establishing toxicological and nutritional differences in the new food compared to a conventional counterpart—differences are analyzed and evaluated, and further