Seismic magnitude scales the amount of slip, the area of the surface ruptured or slipped, and a factor for the resistance or friction encountered. These factors can be estimated for an existing fault to determine the magnitude of past earthquakes, or what might be anticipated for the future. An earthquake's seismic moment can be estimated in various ways, which are the bases of the M, M, M, M, M, M, and M scales, all subtypes of the generic M scale. See for details. Seismic moment is considered the most objective measure of an earthquake's "size" in regard of total energy. However, it is
Natural product and therefore natural products are often used as starting points for drug discovery. Natural product constituents have inspired numerous drug discovery efforts that eventually gained approval as new drugs by the U.S. Food and Drug Administration Indigenous peoples and ancient civilizations experimented with various plant and animal parts to determine what effect they might have. Through trial and error in isolated cases, traditional healers or shamans found some sources to provide therapeutic effect, representing knowledge of a crude drug that was passed down through generations in such practices as traditional Chinese medicine and Ayurveda. Extracts of some natural products led