ABO blood group system letter O for "ohne", meaning without or zero; Landsteiner chose the latter.) This classification was adopted by the National Research Council and became variously known as the National Research Council classification, the International classification, and most popularly the "new" Landsteiner classification. The new system was gradually accepted and by the early 1950s, it was universally followed. The first practical use of blood typing in transfusion was by an American physician Reuben Ottenberg in 1907. And the large-scale application started during the First World War (1914-1915) when citric acid was developed as blood clot prevention. Felix Bernstein demonstrated the correct blood
Blood transfusion by using blood type testing to identify a less scarce alternative. Jehovah's Witnesses object to blood transfusions due to their belief that blood is sacred. Although there are clinical situations where transfusion with red blood cells is the only clinically appropriate option, clinicians look at whether alternatives as feasible. This can be due to several reasons, such as patient safety, economic burden or scarcity of blood. Guidelines recommend blood transfusions should be reserved for patients with or at risk of cardiovascular instability due to the degree of their anaemia. In these cases parenteral iron is recommended. Thus far, there are