Nitric acid rises to 1 at a temperature of 250 °C. Nitric acid can act as a base with respect to an acid such as sulfuric acid: The nitronium ion, , is the active reagent in aromatic nitration reactions. Since nitric acid has both acidic and basic properties, it can undergo an autoprotolysis reaction, similar to the self-ionization of water: Nitric acid reacts with most metals, but the details depend on the concentration of the acid and the nature of the metal. Dilute nitric acid behaves as a typical acid in its reaction with most metals. Magnesium, manganese, and zinc liberate H:
Acid perfusion test Acid perfusion test Acid perfusion test, also called the Bernstein test, is a test done to reproduce the pain when the lower esophagus is irrigated with an acid solution in people with GERD (gastroesophageal reflux disease). There will be a negative result in normal people, but a false positive reading may be seen in up to 15% of people. Bernstein test is obsolete nowadays. 24 hour pH monitoring is the gold standard for GERD. However, the initial management is with proton pump inhibitors. If the patient does not respond to it, and continues to have symptoms of GERD, i.e. heartburn,