Carbon dioxide surface, warming the surface and the lower atmosphere. Less energy reaches the upper atmosphere, which is therefore cooler because of this absorption. Increases in atmospheric concentrations of and other long-lived greenhouse gases such as methane, nitrous oxide and ozone have correspondingly strengthened their absorption and emission of infrared radiation, causing the rise in average global temperature since the mid-20th century. Carbon dioxide is of greatest concern because it exerts a larger overall warming influence than all of these other gases combined and because it has a long atmospheric lifetime (hundreds to thousands of years). Not only do increasing carbon dioxide
Nitrous oxide because has a very short duration under normal circumstances, it is less likely to be neurotoxic than other NMDA antagonists. Indeed, in rodents, short-term exposure results in only mild injury that is rapidly reversible, and neuronal death occurs only after constant and sustained exposure. Nitrous oxide also may cause neurotoxicity after extended exposure because of hypoxia. This is especially true of non-medical formulations such as whipped-cream chargers (also known as "whippets" or "nangs"), which never contain oxygen, since oxygen makes cream rancid. Additionally, nitrous oxide depletes vitamin B levels. This can cause serious neurotoxicity if the user has preexisting vitamin