Bromochloromethane such as halon 1211 and 1301 were developed. Due to its ozone depletion potential its production was banned from January 1, 2002, at the "Eleventh Meeting of the Parties for the Montreal Protocol on Substances that Deplete the Ozone Layer". It can be biologically decomposed using the hydrolase enzyme alkylhalidase by the reaction: In the "Enter the Matrix" video game, the player can find a "Chloro-Bromo Methane Gun", which is used as a fire extinguisher. It fires a pressurized cartridge of CBM gas to put out fires. However, due to its chemical properties, firing a cartridge near people causes their
Ozone depletion framework for negotiating international regulations on ozone-depleting substances. That same year, the discovery of the Antarctic ozone hole was announced, causing a revival in public attention to the issue. In 1987, representatives from 43 nations signed the Montreal Protocol. Meanwhile, the halocarbon industry shifted its position and started supporting a protocol to limit CFC production. However, this shift was uneven with DuPont acting more quickly than its European counterparts. DuPont may have feared court action related to increased skin cancer, especially as the EPA had published a study in 1986 claiming that an additional 40 million cases and 800,000 cancer