Acetonitrile formulations for nail polish remover, despite its toxicity. At least two cases have been reported of accidental poisoning of young children by acetonitrile-based nail polish remover, one of which was fatal. Acetone and ethyl acetate are often preferred as safer for domestic use, and acetonitrile has been banned in cosmetic products in the European Economic Area since March 2000. In common with other nitriles, acetonitrile can be metabolised in microsomes, especially in the liver, to produce hydrogen cyanide, as was first shown by Pozzani "et al." in 1959. The first step in this pathway is the oxidation of acetonitrile to
Staple remover Staple remover A staple remover is a device that allows for the quick removal of a staple from a material without causing damage. Also known as a canassas, the best-known form of staple remover, designed for light-gauge staples, consists essentially of "a") two opposing, pivot-mounted pairs of thin, steep wedges and "b") a spring that returns the device to the open position after use. Although a simple metal wedge can be used for the same purpose, and although some staplers (especially small ones about long) feature such a wedge at their hinge end, use of the wedge tends to tear