ABO blood group system and likely predates human migration from Africa. The O01 allele is considered to predate the O02 allele. Some evolutionary biologists theorize that there are four main lineages of the ABO gene and that mutations creating type O have occurred at least three times in humans. From oldest to youngest, these lineages comprise the following alleles: "A101/A201/O09", "B101", "O02" and "O01". The continued presence of the O alleles is hypothesized to be the result of balancing selection. Both theories contradict the previously held theory that type O blood evolved first. It is possible that food and environmental antigens (bacterial, viral, or
Jehovah's Witnesses and blood transfusions of outdated medical beliefs. Dissident Witnesses say the Society's use of Leviticus 17:12 to support its opposition to blood transfusions conflicts with its own teachings that Christians are not under the Mosaic law. Theologian Anthony Hoekema claims the blood prohibited in Levitical laws was not human, but animal. He cites other authors who support his view that the direction at Acts 15 to abstain from blood was intended not as an everlasting covenant but a means of maintaining a peaceful relationship between Jewish and Gentile Christians. He has described as "absurd literalism" the Witnesses' use of a scriptural prohibition on