Bromochloromethane such as halon 1211 and 1301 were developed. Due to its ozone depletion potential its production was banned from January 1, 2002, at the "Eleventh Meeting of the Parties for the Montreal Protocol on Substances that Deplete the Ozone Layer". It can be biologically decomposed using the hydrolase enzyme alkylhalidase by the reaction: In the "Enter the Matrix" video game, the player can find a "Chloro-Bromo Methane Gun", which is used as a fire extinguisher. It fires a pressurized cartridge of CBM gas to put out fires. However, due to its chemical properties, firing a cartridge near people causes their
Montreal Protocol (for example, in the past metered dose inhalers commonly used to treat asthma and chronic obstructive pulmonary disease were exempt) or Halon fire suppression systems used in submarines and aircraft (but not in general industry). The substances in Group I of Annex A are: The provisions of the Protocol include the requirement that the Parties to the Protocol base their future decisions on the current scientific, environmental, technical, and economic information that is assessed through panels drawn from the worldwide expert communities. To provide that input to the decision-making process, advances in understanding on these topics were assessed in 1989,