Periostitis blade of a horned dinosaur. Periostitis Periostitis, also known as periostalgia, is a medical condition caused by inflammation of the periosteum, a layer of connective tissue that surrounds bone. The condition is generally chronic, and is marked by tenderness and swelling of the bone and pain. Acute periostitis is due to infection, is characterized by diffuse formation of pus, severe pain, constitutional symptoms, and usually results in necrosis. It can be caused by excessive physical activity as well, as in the case of medial tibial stress syndrome (also referred to as tibial periostalgia, soleus periostalgia, or shin splints). Congenital infection
Louie (given name) Louie (given name) Louie is a moderately common given name, related to the more common name Louis. It originated in the United Kingdom (where "Louis" is pronounced ) as a more regularly-spelled version without a silent ⟨s⟩. In 2011, it was the 74th most common forename for births in England and Wales, with Louis only slightly more common at 68th. In the United States, "Louis" (there pronounced ) is far more common. The name is unisex; it is usually considered a masculine given name, as a derivation of Louis, but is occasionally given to girls as a diminutive of Louise.