Laudanum are generally confined to controlling diarrhea, alleviating pain, and easing withdrawal symptoms in infants born to mothers addicted to heroin or other opioids. Recent enforcement action by the U.S. Food and Drug Administration (FDA) against manufacturers of paregoric and opium tincture suggests that opium tincture's availability in the U.S. may be in jeopardy. The terms "laudanum" and "tincture of opium" are generally interchangeable, but in contemporary medical practice the latter is used almost exclusively. Paracelsus, a 16th-century Swiss-German alchemist, experimented with various opium concoctions, and recommended opium for reducing pain. One of his preparations, a pill which he extolled as
The Owl Drug Company Francisco, at 1128 Market Street. In 1903, with their contract with the Whitall Tatum Glass Company, they began making triangular, cobalt-blue bottles of various sizes to store poisons in, which was widely emulated. According to the book "Old Owl Drug Bottles & Others" (1968), Owl Drug created a variety of bottles for prescription medicine and pills, and also soda bottles, with an owl sitting atop a mortar and pestle molded into the glass. The bottles were produced in various sizes from up to a (rarer) , over in height. The bottles were also produced in other colors such as green,