Mississippi Jack route to New Orleans. Jacky begins to market her own patent medicine consisting of an alcoholic tincture of opium (better known as laudanum) and Kentucky bourbon, which she markets during medicine shows. Most patent medicines of the time were made up with similar ingredients and similar lavish claims for their efficacy. Use of these compounds was widespread and unregulated. The crew encounter a secret abolitionist running a slave-selling scam in which the "slave" is sold, and then escapes to be sold again and again. Similar plots were sometimes used to trick runaways into cooperating with a sale which would turn
Precision medicine As the exposome is a common concept of epidemiology, precision medicine is intertwined with molecular pathological epidemiology, which is capable of identifying potential biomarkers for precision medicine. The ability to provide precision medicine to patients in routine clinical settings depends on the availability of molecular profiling tests, e.g. individual germline DNA sequencing. While precision medicine currently individualizes treatment mainly on the basis of genomic tests (e.g. Oncotype DX), several promising technology modalities are being developed, from techniques combining spectrometry and computational power to real-time imaging of drug effects in the body. Many different aspects of precision medicine are tested in