Transverse nasal crease Transverse nasal crease The transverse nasal crease or groove is a usually white line between the upper two-thirds and the lower third of the human nose (slightly above the cartilage tip between the bridge and nostrils). It can occur as the result of heredity, accident, or the constant rubbing or wiping of the nose, commonly referred to as the allergic salute. In addition to cases caused by heredity, physical injury, the transverse nasal crease is common in children and adults with chronic nasal allergies. People with allergies often use their hands to remove mucus from a runny nose or rub
Nasal polyp fluid collection causes polyp formation and protrusion into the nasal cavity or sinuses. Polyps which are sessile in the beginning become pedunculated due to gravity. In people with nasal polyps due to aspirin or NSAID sensitivity, the underlying mechanism is due to disorders in the metabolism of arachidonic acid. Exposure to cycloxygenase inhibitors such as aspirin and NSAIDs leads to shunting of products through the lipoxygenase pathway leading to an increased production of products that cause inflammation. In the airway, these inflammatory products lead to symptoms of asthma such as wheezing as well as nasal polyp formation. Nasal polyps can