Metered-dose inhaler stringent set of criteria, they must: In the early days of MDIs the most commonly used propellants were the chlorofluorocarbons CFC-11, CFC-12 and CFC-114. In 2008 the Food and Drug Administration announced that inhalers using chlorofluorocarbons as a propellant, such as Primatene Mist, could no longer be manufactured or sold as of 2012. This followed from the U.S. decision to agree to the 1987 Montreal Protocol on Substances that Deplete the Ozone Layer. Phospholipids are important natural surfactant lipids used in enhancing penetration and bioavailability. Phospholipids act by reducing the high surface tension forces at the air-water interface within the
1987 (What the Fuck Is Going On?) 1987 (What the Fuck Is Going On?) 1987 (What the Fuck Is Going On?) is the debut studio album by British electronic band The Justified Ancients of Mu Mu (the JAMs), later known as the KLF. "1987" was produced using extensive unauthorised samples that plagiarized a wide range of musical works, continuing a theme begun in the JAMs' debut single "All You Need Is Love". These samples provided a deliberately provocative backdrop for beatbox rhythms and cryptic, political raps. The album was released to mixed reviews, but was a commercial success. Shortly after independent release in June 1987, the JAMs