Patent medicine the patent medicines, some of their makers began replacing the opium tincture laudanum with acetanilide, a particularly toxic non-steroidal anti-inflammatory drug with analgesic as well as antipyretic properties that had been introduced into medical practice under the name "Antifebrin" by A. Cahn and P. Hepp in 1886. But this ingredient change probably killed more of the nostrum's users than the original narcotics did, since acetanilide not only caused an alarming cyanosis due to methemoglobinemia but was later discovered to cause liver and kidney damage. The occasional reports of acetanilide-induced cyanosis prompted the search for supposedly less toxic aniline derivatives, such
Mercury Drug Mercury Drug Mercury Drug is a pharmacy chain in the Philippines. The company began on March 1, 1945 with a single drugstore owned by Mariano Que ( ). He named it after Mercury, the messenger of the gods in Roman mythology, whose caduceus is sometimes used as a symbol of medicine. The store began cutting packaged, bulk items into single pieces and selling them individually; this practice is colloquially called "tingí-tingì" in Filipino. During its foundation, it is the second oldest established drugstore chain in the country (after South Star Drug, which established in 1937 - eight years ago). Upon