Hippocampus Hippocampus The hippocampus (named after its resemblance to the seahorse, from the Greek ἱππόκαμπος, "seahorse" from ἵππος "hippos", "horse" and κάμπος "kampos", "sea monster") is a major component of the brains of humans and other vertebrates. Humans and other mammals have two hippocampi, one in each side of the brain. The hippocampus belongs to the limbic system and plays important roles in the consolidation of information from short-term memory to long-term memory, and in spatial memory that enables navigation. The hippocampus is located under the cerebral cortex (allocortical) and in primates in the medial temporal lobe. It contains two main
Intermediate-term memory in neurons. Unlike short-term memory and working memory, intermediate-term memory requires changes in translation to occur in order to function. While ITM requires only changes in translation, induction of long-term memory requires changes in transcription as well. The change from short-term memory to long-term memory is thought to dependent on CREB, which regulates transcription, but because ITM does not involve a change in transcription, it is thought to be independent of CREB activity. According to the definition of ITM proposed by Sutton "et al." in 2001, it disappears completely before long-term memory is induced. Intermediate-term memory Intermediate-term memory (ITM) is