Metered-dose inhaler stringent set of criteria, they must: In the early days of MDIs the most commonly used propellants were the chlorofluorocarbons CFC-11, CFC-12 and CFC-114. In 2008 the Food and Drug Administration announced that inhalers using chlorofluorocarbons as a propellant, such as Primatene Mist, could no longer be manufactured or sold as of 2012. This followed from the U.S. decision to agree to the 1987 Montreal Protocol on Substances that Deplete the Ozone Layer. Phospholipids are important natural surfactant lipids used in enhancing penetration and bioavailability. Phospholipids act by reducing the high surface tension forces at the air-water interface within the
1987 Montreal Alouettes season crowds in its final year. Consequently, the Winnipeg Blue Bombers moved to the East Division to balance out the divisions and played the Argonauts that day instead. The team never played a single game at Olympic Stadium in 1987; both of their preseason games prior to their folding were played on the road (their first preseason game was moved from Olympic Stadium to Canada Games Stadium in Saint John, New Brunswick). 1987 Montreal Alouettes season The 1987 Montreal Alouettes played two preseason games before folding on June 24, 1987, just one day before their scheduled Thursday game against the Toronto