Blood transfusion of transfusing uncrossmatched blood, O-negative blood is used, followed by crossmatch as soon as possible. O-negative is also used for children and women of childbearing age. It is preferable for the laboratory to obtain a pre-transfusion sample in these cases so a type and screen can be performed to determine the actual blood group of the patient and to check for alloantibodies. This chart shows possible matches in blood transfusion between donor and receiver using ABO and Rh system. In the same way that the safety of pharmaceutical products is overseen by pharmacovigilance, the safety of blood and blood products
Jehovah's Witnesses and blood transfusions eating blood to prohibit the medical transfusion of human blood. Osamu Muramoto has argued that the refusal by Jehovah's Witnesses of "life-saving" blood treatment creates serious bio-medical ethical issues. He has criticized the "controlling intervention" of the Watch Tower Society by means of what he claims is information control and its policy of penalising members who accept blood transfusions or advocate freedom to choose blood-based treatment. He says the threat of being classified as a disassociated Witness and subsequently shunned by friends and relatives who are members coerces Jehovah's Witnesses to accept and obey the prohibition on blood transfusions. In