Laudanum Uniform Controlled Substances Act, which regulated opium tincture (Laudanum) as a Schedule II substance (currently DEA #9630), placing even tighter controls on the drug. By the late 20th century, laudanum's use was almost exclusively confined to treating severe diarrhea. The current prescribing information for laudanum in the US states that opium tincture's sole indication is as an anti-diarrheal, although the drug is occasionally prescribed off-label for treating pain and neonatal withdrawal syndrome. Several historical varieties of laudanum exist, including Paracelsus' laudanum, Sydenham's Laudanum (also known as "tinctura opii crocata"), benzoic laudanum ("tinctura opii benzoica"), and deodorized tincture of opium (the
The Owl Drug Company Francisco, at 1128 Market Street. In 1903, with their contract with the Whitall Tatum Glass Company, they began making triangular, cobalt-blue bottles of various sizes to store poisons in, which was widely emulated. According to the book "Old Owl Drug Bottles & Others" (1968), Owl Drug created a variety of bottles for prescription medicine and pills, and also soda bottles, with an owl sitting atop a mortar and pestle molded into the glass. The bottles were produced in various sizes from up to a (rarer) , over in height. The bottles were also produced in other colors such as green,