Laudanum are generally confined to controlling diarrhea, alleviating pain, and easing withdrawal symptoms in infants born to mothers addicted to heroin or other opioids. Recent enforcement action by the U.S. Food and Drug Administration (FDA) against manufacturers of paregoric and opium tincture suggests that opium tincture's availability in the U.S. may be in jeopardy. The terms "laudanum" and "tincture of opium" are generally interchangeable, but in contemporary medical practice the latter is used almost exclusively. Paracelsus, a 16th-century Swiss-German alchemist, experimented with various opium concoctions, and recommended opium for reducing pain. One of his preparations, a pill which he extolled as
Mosses from an Old Manse Mosses from an Old Manse Mosses from an Old Manse is a short story collection by Nathaniel Hawthorne, first published in 1846. The collection includes several previously-published short stories, and was named in honor of The Old Manse where Hawthorne and his wife lived for the first three years of their marriage. The first edition was published in 1846. Hawthorne seems to have been paid $75 for the publication. Many of the tales collected in "Mosses from an Old Manse" are allegories and, typical of Hawthorne, focus on the negative side of human nature. Hawthorne's friend Herman Melville noted this