Ixodes holocyclus tick might "squeeze" saliva and gut contents into the host. Specifically, application of methylated spirit, nail polish remover, turpentine or ti-tree oil is thought to irritate the tick and make it inject more of the noxious substances. Spreading butter or oil over the tick is no longer recommended either. Application of pyrethrin (or pyrethroid) insecticides has been suggested 'as a narcotic and a toxicant, which prevents the tick from injecting its saliva' but with this method the tick may remain physically attached for 24 hrs before it drops off dead. Do not use pyrethrin containing products on cats as this
Nail polish and carbon disulfide may have adverse effects on reproductive health. These effects may including birth defects, low birth weight, miscarriage, and preterm birth. Nail polish formulations may include ingredients that are toxic or affect other health problems. One controversial family of ingredient are phthalates, which are implicated as endocrine disruptors and linked to problems in the endocrine system and increased risk of diabetes. Manufacturers have been pressured by consumer groups to reduce or to eliminate potentially-toxic ingredients, and in September 2006, several companies agreed to phase out dibutyl phthalates. There are no universal consumer safety standards for nail polish, however,