Seismic analysis and models the actual physics, much like common video games often have "physics engines". Very large and complex buildings can be modeled in this way (such as the Osaka International Convention Center). Structural analysis methods can be divided into the following five categories. This approach defines a series of forces acting on a building to represent the effect of earthquake ground motion, typically defined by a seismic design response spectrum. It assumes that the building responds in its fundamental mode. For this to be true, the building must be low-rise and must not twist significantly when the ground moves. The
Natural product and therefore natural products are often used as starting points for drug discovery. Natural product constituents have inspired numerous drug discovery efforts that eventually gained approval as new drugs by the U.S. Food and Drug Administration Indigenous peoples and ancient civilizations experimented with various plant and animal parts to determine what effect they might have. Through trial and error in isolated cases, traditional healers or shamans found some sources to provide therapeutic effect, representing knowledge of a crude drug that was passed down through generations in such practices as traditional Chinese medicine and Ayurveda. Extracts of some natural products led