Hydrazoic acid was originally prepared by the reaction of aqueous hydrazine with nitrous acid. Other oxidizing agents, such as hydrogen peroxide, nitrosyl chloride, trichloramine or nitric acid, can also be used. In its properties hydrazoic acid shows some analogy to the halogen acids, since it forms poorly soluble (in water) lead, silver and mercury(I) salts. The metallic salts all crystallize in the anhydrous form and decompose on heating, leaving a residue of the pure metal. It is a weak acid (p"K" = 4.75.) Its heavy metal salts are explosive and readily interact with the alkyl iodides. Azides of heavier alkali metals (excluding
Acid–base imbalance Any combination is possible, as metabolic acidosis and alkalosis can co exist together. The traditional approach to the study of acid–base physiology has been the empirical approach. The main variants are the base excess approach and the bicarbonate approach. The quantitative approach introduced by Peter A Stewart in 1978 is newer. There are numerous reasons that each of the four processes can occur (detailed in each article). Generally speaking, sources of acid gain include: Sources of acid loss include: The body's acid–base balance is tightly regulated. Several buffering agents exist which reversibly bind hydrogen ions and impede any change in