Global cooling wrote their 1971 paper, climatologists had not yet recognized the significance of greenhouse gases other than water vapor and carbon dioxide, such as methane, nitrous oxide, and chlorofluorocarbons. Early in that decade, carbon dioxide was the only widely studied human-influenced greenhouse gas. The attention drawn to atmospheric gases in the 1970s stimulated many discoveries in subsequent decades. As the temperature pattern changed, global cooling was of waning interest by 1979. A common argument used to dispute the significance of human caused climate change, which TIME Magazine calls the Ice Age Fallacy, is to allege that scientists showed concerns about global
Nitrous oxide that cuts off their supply of fresh air. Long-term exposure to nitrous oxide may cause vitamin B deficiency. It inactivates the cobalamin form of vitamin B by oxidation. Symptoms of vitamin B deficiency, including sensory neuropathy, myelopathy, and encephalopathy, may occur within days or weeks of exposure to nitrous oxide anaesthesia in people with subclinical vitamin B deficiency. Symptoms are treated with high doses of vitamin B, but recovery can be slow and incomplete. People with normal vitamin B levels have stores to make the effects of nitrous oxide insignificant, unless exposure is repeated and prolonged (nitrous oxide abuse). Vitamin