Patent medicine the patent medicines, some of their makers began replacing the opium tincture laudanum with acetanilide, a particularly toxic non-steroidal anti-inflammatory drug with analgesic as well as antipyretic properties that had been introduced into medical practice under the name "Antifebrin" by A. Cahn and P. Hepp in 1886. But this ingredient change probably killed more of the nostrum's users than the original narcotics did, since acetanilide not only caused an alarming cyanosis due to methemoglobinemia but was later discovered to cause liver and kidney damage. The occasional reports of acetanilide-induced cyanosis prompted the search for supposedly less toxic aniline derivatives, such
New Looks from an Old Lover New Looks from an Old Lover "New Looks From An Old Lover" is a song recorded by American country music artist B.J. Thomas. It was released in July 1983 as the second single from the album "New Looks". "New Looks From An Old Lover" was B.J. Thomas' third number one on the country chart. The single went to number one for one week and spent a total of thirteen weeks on the country chart. It was Thomas' final number one hit on the U.S. charts. The song was written by Thomas' wife Gloria, along with Red Lane and Lathan Hudson.