Laudanum are generally confined to controlling diarrhea, alleviating pain, and easing withdrawal symptoms in infants born to mothers addicted to heroin or other opioids. Recent enforcement action by the U.S. Food and Drug Administration (FDA) against manufacturers of paregoric and opium tincture suggests that opium tincture's availability in the U.S. may be in jeopardy. The terms "laudanum" and "tincture of opium" are generally interchangeable, but in contemporary medical practice the latter is used almost exclusively. Paracelsus, a 16th-century Swiss-German alchemist, experimented with various opium concoctions, and recommended opium for reducing pain. One of his preparations, a pill which he extolled as
Old Crow Medicine Show multiple times at other major festivals, e.g., Bonnaroo Music Festival, MerleFest, Telluride Bluegrass Festival, Hardly Strictly Bluegrass Festival, and Newport Folk Festival. They have made frequent guest appearances on "A Prairie Home Companion" with Garrison Keillor. The group received the 2013 Trailblazer Award from the Americana Music Association, performing at the Americana Honors & Awards Show. Publishing administrator Downtown Music Publishing represents the works of Old Crow Medicine Show. Ketch Secor and Critter Fuqua first met in the seventh grade in Harrisonburg, Virginia and began playing music together. They performed open mics at the Little Grill diner, as did Robert