How Many Times Can We Say Goodbye How Many Times Can We Say Goodbye How Many Times Can We Say Goodbye is an album recorded by Dionne Warwick, her sixth for the Arista label. It was recorded during the spring of 1983 and was released that fall. The LP was originally issued as number AL 8-8104 in the Arista Catalog. Despite strong reviews, it was a commercial disappointment, stalling at number 57 on "Billboard"'s album chart. Two singles came from the album, 'How Many Times Can We Say Goodbye?' (a duet with album producer Luther Vandross) which hit #4 Adult Contemporary and #27 on Billboard's Hot 100
Cruciferous vegetables to isothiocyanates (ITCs) by the action of myrosinase. ITCs, possibly a bioactive component in cruciferous vegetables, are being investigated for their chemopreventive and chemotherapeutic effects. As one example in laboratory research, ITCs such as phenethyl isothiocyanate reduced levels of the oncoprotein MCL1. Other in vitro research indicates ITCs may affect levels of the BCR-ABL fusion protein, the oncoprotein affecting mechanisms of leukemia. Chemicals contained in cruciferous vegetables induce the expression of the liver enzyme CYP1A2. Furthermore, some drugs such as haloperidol and theophylline are metabolized by CYP1A2. Consequently, consumption of cruciferous vegetables may decrease bioavailability and half-life of these drugs.