Mercury (element) used in teething powders for infants. The mercury-containing organohalide merbromin (sometimes sold as Mercurochrome) is still widely used but has been banned in some countries such as the U.S. Mercury and most of its compounds are extremely toxic and must be handled with care; in cases of spills involving mercury (such as from certain thermometers or fluorescent light bulbs), specific cleaning procedures are used to avoid exposure and contain the spill. Protocols call for physically merging smaller droplets on hard surfaces, combining them into a single larger pool for easier removal with an eyedropper, or for gently pushing the spill
Substantial equivalence conference of officials and industry), although the term "substantial equivalence" was not used. Adopting the term, "substantial equivalence" was formulated as a food safety policy by the OECD, first described in their 1993 report, "Safety Evaluation of Foods Derived by Modern Biotechnology: Concepts and Principles. The term was borrowed from the FDA's 1976 substantial equivalence definition for new medical devices—under Premarket Notification 510(k), a new Class II device that is essentially similar to an existing device can be cleared for release without further testing. The underlying approach of comparing a new product or technique to an existing one has long