Carbon dioxide surface, warming the surface and the lower atmosphere. Less energy reaches the upper atmosphere, which is therefore cooler because of this absorption. Increases in atmospheric concentrations of and other long-lived greenhouse gases such as methane, nitrous oxide and ozone have correspondingly strengthened their absorption and emission of infrared radiation, causing the rise in average global temperature since the mid-20th century. Carbon dioxide is of greatest concern because it exerts a larger overall warming influence than all of these other gases combined and because it has a long atmospheric lifetime (hundreds to thousands of years). Not only do increasing carbon dioxide
Sulfur dioxide are mediated via ATP-dependent calcium channels and L-type ("dihydropyridine") calcium channels. Endogenous sulfur dioxide is also a potent antiinflammatory, antioxidant and cytoprotective agent. It lowers blood pressure and slows hypertensive remodeling of blood vessels, especially thickening of their intima. It also regulates lipid metabolism. Endogenous sulfur dioxide also diminishes myocardial damage, caused by isoproterenol adrenergic hyperstimulation, and strengthens the myocardial antioxidant defense reserve. Being easily condensed and possessing a high heat of evaporation, sulfur dioxide is a candidate material for refrigerants. Prior to the development of chlorofluorocarbons, sulfur dioxide was used as a refrigerant in home refrigerators. Sulfur dioxide is