Nasal spray efficient way of transporting drugs with potential use in crossing the blood–brain barrier. Antihistamines work by competing for receptor sites to block the function of histamine, thereby reducing the inflammatory effect. Antihistamine nasal sprays include: Corticosteroid nasal sprays can be used to relieve the symptoms of sinusitis, hay fever, allergic rhinitis and non-allergic (perennial) rhinitis. They can reduce inflammation and histamine production in the nasal passages, and have been shown to relieve nasal congestion, runny nose, itchy nose and sneezing. Side effects may include headaches, nausea and nose bleeds. Corticosteroid nasal sprays include: Influenza vaccine is available in the form
Nasal irrigation cases of fatal naegleriasis have occurred due to nasal insufflation of the amoeba "Naegleria fowleri" from untreated tap water. Flushing the nasal cavity can soothe inflamed tissue and remove irritants like allergens; it may help clear mucus. The water should not be tap water, which may contain small amounts of bacteria that are safe to drink but may be dangerous in the nose. The water should be sterile or filtered for micro-organisms; if tap water is used it should be boiled. Saline solution is also sometimes used. A number of other compounds may be included in irrigation fluids such as