Acetonitrile formulations for nail polish remover, despite its toxicity. At least two cases have been reported of accidental poisoning of young children by acetonitrile-based nail polish remover, one of which was fatal. Acetone and ethyl acetate are often preferred as safer for domestic use, and acetonitrile has been banned in cosmetic products in the European Economic Area since March 2000. In common with other nitriles, acetonitrile can be metabolised in microsomes, especially in the liver, to produce hydrogen cyanide, as was first shown by Pozzani "et al." in 1959. The first step in this pathway is the oxidation of acetonitrile to
Nail art and scissors to shape and trim the nails. In 1892, Dr. Sitts' niece invented a nail care line for women of any social class, which eventually reached United States Salons. Prior to then women had short, almond shaped nails and often used oils for additional shine or tint. Not long after, in 1907, the first liquid nail polish was invented, although it was colorless. Soon thereafter, it was available in variety of different colors. In 1925, the Lunar manicure (today known as the Half-Moon manicure) was seen everywhere. Reds and pinks were used on the nail bed while avoiding the