Acetonitrile formulations for nail polish remover, despite its toxicity. At least two cases have been reported of accidental poisoning of young children by acetonitrile-based nail polish remover, one of which was fatal. Acetone and ethyl acetate are often preferred as safer for domestic use, and acetonitrile has been banned in cosmetic products in the European Economic Area since March 2000. In common with other nitriles, acetonitrile can be metabolised in microsomes, especially in the liver, to produce hydrogen cyanide, as was first shown by Pozzani "et al." in 1959. The first step in this pathway is the oxidation of acetonitrile to
World Apple and Pear Association World Apple and Pear Association The World Apple and Pear Association (WAPA) is a trade association established in 2001 representing major apple and pear producing countries globally. The Association provides a forum for member discussion and reviews market information related to fruit trees. In 2007, world apple production reached 66 million tonnes while pear production amounted to 20.5 million tonnes. The secretariat of the Association is based in Brussels. WAPA provides its members a forum to discuss issues affecting pear and apple producing countries and the international marketing of apples and pears. WAPA disseminates market information and is responsible for