Acetonitrile formulations for nail polish remover, despite its toxicity. At least two cases have been reported of accidental poisoning of young children by acetonitrile-based nail polish remover, one of which was fatal. Acetone and ethyl acetate are often preferred as safer for domestic use, and acetonitrile has been banned in cosmetic products in the European Economic Area since March 2000. In common with other nitriles, acetonitrile can be metabolised in microsomes, especially in the liver, to produce hydrogen cyanide, as was first shown by Pozzani "et al." in 1959. The first step in this pathway is the oxidation of acetonitrile to
Nail polish Nail polish Nail polish (also known as nail varnish) is a lacquer that can be applied to the human fingernail or toenails to decorate and protect the nail plates. The formulation has been revised repeatedly to enhance its decorative effects, and to suppress cracking or flaking. Nail polish consists of a mix of an organic polymer and several other components, depending on the brand. People use this liquid to create both simple and complicated designs with bright colors, charms, or other. Nail Polish originated in China and dates back to 3000 BC. Around 600 BC, during the Zhou dynasty, the