Patent medicine the patent medicines, some of their makers began replacing the opium tincture laudanum with acetanilide, a particularly toxic non-steroidal anti-inflammatory drug with analgesic as well as antipyretic properties that had been introduced into medical practice under the name "Antifebrin" by A. Cahn and P. Hepp in 1886. But this ingredient change probably killed more of the nostrum's users than the original narcotics did, since acetanilide not only caused an alarming cyanosis due to methemoglobinemia but was later discovered to cause liver and kidney damage. The occasional reports of acetanilide-induced cyanosis prompted the search for supposedly less toxic aniline derivatives, such
An Old Master bullocks bent to their yoke, and lifted the waggon from the gluepot. He was 'An Old Master'." A reviewer in "The Telegraph" (Brisbane) noted: " Mr. Dennis's work is not confined to the rhyming in slang, which were the sole attraction of some of his earlier and lucrative efforts. "An Old Master," with which the volume opens, stands out as one of Mr. Dennis's best." An Old Master "An Old Master" is a poem by Australian poet C. J. Dennis. It was first published in "The Bulletin" magazine on 4 August 1910, and later in the poet's poetry collection "Backblock