Neuroanatomy of memory Neuroanatomy of memory The neuroanatomy of memory encompasses a wide variety of anatomical structures in the brain. The hippocampus is a structure in the brain that has been associated with various memory functions. It is part of the limbic system, and lies next to the medial temporal lobe. It is made up of two structures, the Ammon's Horn, and the Dentate gyrus, each containing different types of cells. There is evidence that the hippocampus contains cognitive maps in humans. In one study, single-cell recordings were taken from electrodes implanted in a rat's hippocampus, and it was found that certain neurons
Epigenetics in learning and memory G9a/GLP in the EC, but not in the hippocampus, results in the enhancement of long-term memory formation. In addition, G9a/GLP inhibition in the entorhinal cortex altered histone H3 lysine 9 dimethylation in the Cornu Ammonis area 1 of the hippocampus, suggesting the importance of this complex in mediating connectivity between these two brain regions. Therefore, the G9a/GLP complex plays an important role in histone methylation and long term memory formation in the hippocampus and the EC. Histone methylation marks are also correlated with other epigenetic modifications, such as histone deacetylation and DNA methylation, in the context of learning and memory.