Trifluoroacetic acid Trifluoroacetic acid Trifluoroacetic acid (TFA) is an organofluorine compound with the chemical formula CFCOH. It is a structural analogue of acetic acid with all three of the acetyl group’s hydrogen atoms replaced by fluorine atoms and is a colorless liquid with a vinegar like odor. TFA is a stronger acid than acetic acid, having an acid ionisation constant that is approximately 34,000 times higher, as the highly electronegative fluorine atoms and consequent electron-withdrawing nature of the trifluoromethyl group weakens the oxygen-hydrogen bond (allowing for greater acidity) and stabilises the anionic conjugate base. TFA is widely used in organic chemistry for
Syringic acid in vinegar. Syringic acid can be enzymatically polymerised. Laccase and peroxidase induced the polymerization of syringic acid to give a poly(1,4-phenylene oxide) bearing a carboxylic acid at one end and a phenolic hydroxyl group at the other. Syringic acid Syringic acid is a naturally occurring "O"-methylated trihydroxybenzoic acid, a type of chemical compound. Syringic acid can be found in "Ardisia elliptica". Syringic acid can be prepared by selectively hydrolyzing (demethylating) eudesmic acid with 20% sulfuric acid. Syringic acid can be found in the açaí palm ("Euterpe oleracea") and its oil (1,073 ± 62 mg/kg). It is also present in wine.