Nitrous oxide inside the cells, by a process catalyzed by the enzyme nitrous oxide reductase. Nitrous oxide has significant global warming potential as a greenhouse gas. On a per-molecule basis, considered over a 100-year-period, nitrous oxide has 298 times the atmospheric heat-trapping ability of carbon dioxide (), however, because of its low concentration (less than 1/1000 of that of ), its contribution to the greenhouse effect is less than one-third that of carbon dioxide, and also less than water vapour and methane. On the other hand, since 38% or more of the entering the atmosphere is the result of human activity, and
Nitrous oxide used by almost half a million young people at nightspots, festivals, and parties. The legality of that use varies greatly from country to country, and even from city to city in some countries. The major safety hazards of nitrous oxide come from the fact that it is a compressed liquefied gas, an asphyxiation risk, and a dissociative anaesthetic. While relatively non-toxic, nitrous oxide has a number of recognized ill effects on human health, whether through breathing it in or by contact of the liquid with skin or eyes. Nitrous oxide is a significant occupational hazard for surgeons, dentists, and nurses.