Global cooling wrote their 1971 paper, climatologists had not yet recognized the significance of greenhouse gases other than water vapor and carbon dioxide, such as methane, nitrous oxide, and chlorofluorocarbons. Early in that decade, carbon dioxide was the only widely studied human-influenced greenhouse gas. The attention drawn to atmospheric gases in the 1970s stimulated many discoveries in subsequent decades. As the temperature pattern changed, global cooling was of waning interest by 1979. A common argument used to dispute the significance of human caused climate change, which TIME Magazine calls the Ice Age Fallacy, is to allege that scientists showed concerns about global
Nitrous oxide because has a very short duration under normal circumstances, it is less likely to be neurotoxic than other NMDA antagonists. Indeed, in rodents, short-term exposure results in only mild injury that is rapidly reversible, and neuronal death occurs only after constant and sustained exposure. Nitrous oxide also may cause neurotoxicity after extended exposure because of hypoxia. This is especially true of non-medical formulations such as whipped-cream chargers (also known as "whippets" or "nangs"), which never contain oxygen, since oxygen makes cream rancid. Additionally, nitrous oxide depletes vitamin B levels. This can cause serious neurotoxicity if the user has preexisting vitamin