Metered-dose inhaler stringent set of criteria, they must: In the early days of MDIs the most commonly used propellants were the chlorofluorocarbons CFC-11, CFC-12 and CFC-114. In 2008 the Food and Drug Administration announced that inhalers using chlorofluorocarbons as a propellant, such as Primatene Mist, could no longer be manufactured or sold as of 2012. This followed from the U.S. decision to agree to the 1987 Montreal Protocol on Substances that Deplete the Ozone Layer. Phospholipids are important natural surfactant lipids used in enhancing penetration and bioavailability. Phospholipids act by reducing the high surface tension forces at the air-water interface within the
MOESI protocol other processors that are sharing that cache line. Depending on the implementation it may simply tell them to invalidate their copies (moving its own copy to the Modified state), or it may tell them to update their copies with the new contents (leaving its own copy in the Owned state). MOESI protocol In computing, MOESI is a full cache coherency protocol that encompasses all of the possible states commonly used in other protocols. In addition to the four common MESI protocol states, there is a fifth "Owned" state representing data that is both modified and shared. This avoids the need