Mississippi Jack route to New Orleans. Jacky begins to market her own patent medicine consisting of an alcoholic tincture of opium (better known as laudanum) and Kentucky bourbon, which she markets during medicine shows. Most patent medicines of the time were made up with similar ingredients and similar lavish claims for their efficacy. Use of these compounds was widespread and unregulated. The crew encounter a secret abolitionist running a slave-selling scam in which the "slave" is sold, and then escapes to be sold again and again. Similar plots were sometimes used to trick runaways into cooperating with a sale which would turn
Drug discovery Drug discovery In the fields of medicine, biotechnology and pharmacology, drug discovery is the process by which new candidate medications are discovered. Historically, drugs were discovered through identifying the active ingredient from traditional remedies or by serendipitous discovery. Later chemical libraries of synthetic small molecules, natural products or extracts were screened in intact cells or whole organisms to identify substances that have a desirable therapeutic effect in a process known as classical pharmacology. Since sequencing of the human genome which allowed rapid cloning and synthesis of large quantities of purified proteins, it has become common practice to use high throughput