Acetonitrile formulations for nail polish remover, despite its toxicity. At least two cases have been reported of accidental poisoning of young children by acetonitrile-based nail polish remover, one of which was fatal. Acetone and ethyl acetate are often preferred as safer for domestic use, and acetonitrile has been banned in cosmetic products in the European Economic Area since March 2000. In common with other nitriles, acetonitrile can be metabolised in microsomes, especially in the liver, to produce hydrogen cyanide, as was first shown by Pozzani "et al." in 1959. The first step in this pathway is the oxidation of acetonitrile to
Nail polish and half-moon on the nail bed. Men have begun to wear clear polish on their nails to protect them from breakage, and as recorded from 2013, a few men have also started to wear colored nail polish on their toenails, and some even on their hands, possibly arising from its use by rock music musicians or in Goth subculture. While pastel colors such as pink are not typically worn by men, colors such as black, gun metal, silver, olive green, or brown are more often seen. This is especially true in warm climate areas where open-toed shoes are worn and