Acetonitrile formulations for nail polish remover, despite its toxicity. At least two cases have been reported of accidental poisoning of young children by acetonitrile-based nail polish remover, one of which was fatal. Acetone and ethyl acetate are often preferred as safer for domestic use, and acetonitrile has been banned in cosmetic products in the European Economic Area since March 2000. In common with other nitriles, acetonitrile can be metabolised in microsomes, especially in the liver, to produce hydrogen cyanide, as was first shown by Pozzani "et al." in 1959. The first step in this pathway is the oxidation of acetonitrile to
Pear New Mill storey, where round-headed arches were used. The window heads were picked out in yellow brick. The Pear 'signature theme' of the building includes a large pear-shaped concrete cupola on top of the water tower at the South-East corner, and pear-shaped finials at each corner of the flat roof. Ornate terracotta friezes over the main entrances continue the theme with bas-relief depictions of pear tree leaves and fruit. It was powered by a George Saxon 5000 hp twin Manhattan Compound, made in 1912. Running at 180 psi, it had two 30 in HP cylinders and two 60 in low-pressure cylinder. It