Patent medicine the patent medicines, some of their makers began replacing the opium tincture laudanum with acetanilide, a particularly toxic non-steroidal anti-inflammatory drug with analgesic as well as antipyretic properties that had been introduced into medical practice under the name "Antifebrin" by A. Cahn and P. Hepp in 1886. But this ingredient change probably killed more of the nostrum's users than the original narcotics did, since acetanilide not only caused an alarming cyanosis due to methemoglobinemia but was later discovered to cause liver and kidney damage. The occasional reports of acetanilide-induced cyanosis prompted the search for supposedly less toxic aniline derivatives, such
Volunteer (Old Crow Medicine Show album) Volunteer (Old Crow Medicine Show album) Volunteer is the sixth studio album by folk band Old Crow Medicine Show. It was released in April 2018 under Columbia Nashville. The album is the band's first to feature Joe Andrews who plays on every track and has subsequently become a full band member. The album received a Metacritic score of 85 based on 6 critics, indicating universal acclaim. The album debuted at No. 14 on Top Country Albums, No. 1 on Bluegrass Albums, and No. 7 on Americana/Folk Albums, with 7,000 equivalent album units (6,500 in traditional album sales) in its first