Acetonitrile formulations for nail polish remover, despite its toxicity. At least two cases have been reported of accidental poisoning of young children by acetonitrile-based nail polish remover, one of which was fatal. Acetone and ethyl acetate are often preferred as safer for domestic use, and acetonitrile has been banned in cosmetic products in the European Economic Area since March 2000. In common with other nitriles, acetonitrile can be metabolised in microsomes, especially in the liver, to produce hydrogen cyanide, as was first shown by Pozzani "et al." in 1959. The first step in this pathway is the oxidation of acetonitrile to
Cosmetology and cosmetology industries, some of the products used in hair dyes and nail applications contain chemicals that have been shown to have adverse health effects for cosmetologists. A chemical combination known as the toxic trio is often part of the ingredient list in nail polish, hair dyes, and nail polish removers. The toxic trio consists of formaldehyde, toluene and dibutyl phthalate (DBP). DBP is frequently found in nail polish and is used as a binder to increase the amount of time the polish stays on the nail. Toluene is an industrial solvent and is usually in nail polish removers. Formaldehyde