Metered-dose inhaler stringent set of criteria, they must: In the early days of MDIs the most commonly used propellants were the chlorofluorocarbons CFC-11, CFC-12 and CFC-114. In 2008 the Food and Drug Administration announced that inhalers using chlorofluorocarbons as a propellant, such as Primatene Mist, could no longer be manufactured or sold as of 2012. This followed from the U.S. decision to agree to the 1987 Montreal Protocol on Substances that Deplete the Ozone Layer. Phospholipids are important natural surfactant lipids used in enhancing penetration and bioavailability. Phospholipids act by reducing the high surface tension forces at the air-water interface within the
The Rise and Fall of English Montreal The Rise and Fall of English Montreal The Rise and Fall of English Montreal is a 1993 Canadian documentary film directed by William Weintraub and produced by the National Film Board of Canada in Montreal. The film deals with exodus of English-speaking Quebecers that began in the 1960s and was accelerated by the Quebec general election, 1976. The film includes interviews with English-speaking professionals and students that are preparing to leave Montreal, joining an exodus of 300,000 anglophones that left the province in the last two decades. This exodus is reflected in over 100 English-speaking schools that have closed in