ABO blood group system (and Factor VIII) than do non-O individuals. In addition, vWF is degraded more rapidly due to the higher prevalence of blood group O with the Cys1584 variant of vWF (an amino acid polymorphism in VWF): the gene for ADAMTS13 (vWF-cleaving protease) maps to the ninth chromosome (9q34), the same locus as ABO blood type. Higher levels of vWF are more common amongst people who have had ischemic stroke (from blood clotting) for the first time. The results of this study found that the occurrence was not affected by ADAMTS13 polymorphism, and the only significant genetic factor was the person's blood
Blood type personality theory methodology of his conclusions was unclear. Because of this, he was heavily criticized by the Japanese psychological community, although his books remain popular. His son, Toshitaka Nomi, continued to promote the theory with a series of books and by running the Institute of Blood Type Humanics. He later established the Human Science ABO Center for further research and publication in 2004. Some researchers believe blood types are associated with personality traits. Many medical surveys have been conducted, such as those for hormone secretion traits (DBH, COMT, MAO etc.), or the blood-type antigens in neurons, or the antigens expressed on surfaces