Acid–base reaction models as theories that complement each other. For example the current Lewis model has the broadest definition of what an acid and base are, with the Bronsted-Lowry theory being a subset of what acids and bases are, and the Arrhenius theory being the most restrictive. The first scientific concept of acids and bases was provided by Lavoisier in around 1776. Since Lavoisier's knowledge of strong acids was mainly restricted to oxoacids, such as (nitric acid) and (sulfuric acid), which tend to contain central atoms in high oxidation states surrounded by oxygen, and since he was not aware of the true
Acid perfusion test hoarseness, chronic cough, then 24 hr pH monitoring should be considered. Acid perfusion test Acid perfusion test, also called the Bernstein test, is a test done to reproduce the pain when the lower esophagus is irrigated with an acid solution in people with GERD (gastroesophageal reflux disease). There will be a negative result in normal people, but a false positive reading may be seen in up to 15% of people. Bernstein test is obsolete nowadays. 24 hour pH monitoring is the gold standard for GERD. However, the initial management is with proton pump inhibitors. If the patient does not respond