Metered-dose inhaler stringent set of criteria, they must: In the early days of MDIs the most commonly used propellants were the chlorofluorocarbons CFC-11, CFC-12 and CFC-114. In 2008 the Food and Drug Administration announced that inhalers using chlorofluorocarbons as a propellant, such as Primatene Mist, could no longer be manufactured or sold as of 2012. This followed from the U.S. decision to agree to the 1987 Montreal Protocol on Substances that Deplete the Ozone Layer. Phospholipids are important natural surfactant lipids used in enhancing penetration and bioavailability. Phospholipids act by reducing the high surface tension forces at the air-water interface within the
Montreal Economic Institute Montreal Economic Institute The Montreal Economic Institute (MEI) is a non-profit research organization (or think tank) based in Montreal, Quebec, Canada. It aims at promoting economic liberalism through economic education of the general public and what it regards as efficient public policies in Quebec and Canada through studies and conferences. Its research areas include different topics such as health care, education, taxation, labour, agriculture and the environment. Its studies are often mentioned in the media. The MEI was incorporated in July 1987, after being created by a group of Québec intellectuals and businessmen as the continuation of the Institut économique