Blood type transfusion can be considered safe as long as the serum of the recipient does not contain antibodies for the blood cell antigens of the donor. The "ABO system" is the most important blood-group system in human-blood transfusion. The associated anti-A and anti-B antibodies are usually "immunoglobulin M", abbreviated IgM, antibodies. ABO IgM antibodies are produced in the first years of life by sensitization to environmental substances such as food, bacteria, and viruses. The original terminology used by Karl Landsteiner in 1901 for the classification was A/B/C; in later publications "C" became "O". Type O is often called "0" ("zero", or
Hh blood group Hh blood group The h/h blood group, also known as Oh or the Bombay blood group, is a rare blood type. This blood phenotype was first discovered in Bombay, now known as Mumbai, in India, by Dr. Y. M. Bhende in 1952. It is mostly found in India, Pakistan, and Iran. The first person found to have the Bombay phenotype had an interesting blood type that reacted to other blood types in a way never seen before. The serum contained antibodies that reacted with all red blood cells' normal ABO phenotypes. The red blood cells appeared to lack all of