Aspergillic acid acetic acid gives a diketopiperazine. Hydrolysis with HBr yields a mixture of -leucine and -isoleucine. These reaction schemes can be seen below: Aspergillic acid Aspergillic acid is an organic chemical compound with the molecular formula CHNO. It has a pale yellow crystalline appearance. Aspergillic acid is most commonly known as an antibiotic and antifungal agent that is derived from certain strains of the fungus "Aspergillus flavus". In 1940 Edwin C. White and Justina H. Hill discovered that a fungal strain of "Aspergillus flavus" growing in a surface culture on a tryptone-salt was capable of producing a bactericidal filtrate. It has
Azelaic acid Azelaic acid Azelaic acid is an organic compound with the formula HOOC(CH)COOH. This saturated dicarboxylic acid exists as a white powder. It is found in wheat, rye, and barley. It is a precursor to diverse industrial products including polymers and plasticizers, as well as being a component of a number of hair and skin conditioners. Azelaic acid is industrially produced by the ozonolysis of oleic acid. The side product is nonanoic acid. It is produced naturally by "Malassezia furfur" (also known as "Pityrosporum ovale"), a yeast that lives on normal skin. The bacterial degradation of nonanoic acid gives azelaic acid.