Nitric acid Nitric acid can oxidize non-active metals such as copper and silver. With these non-active or less electropositive metals the products depend on temperature and the acid concentration. For example, copper reacts with dilute nitric acid at ambient temperatures with a 3:8 stoichiometry: The nitric oxide produced may react with atmospheric oxygen to give nitrogen dioxide. With more concentrated nitric acid, nitrogen dioxide is produced directly in a reaction with 1:4 stoichiometry: Upon reaction with nitric acid, most metals give the corresponding nitrates. Some metalloids and metals give the oxides; for instance, Sn, As, Sb, and Ti are oxidized into SnO,
Acid–base imbalance Any combination is possible, as metabolic acidosis and alkalosis can co exist together. The traditional approach to the study of acid–base physiology has been the empirical approach. The main variants are the base excess approach and the bicarbonate approach. The quantitative approach introduced by Peter A Stewart in 1978 is newer. There are numerous reasons that each of the four processes can occur (detailed in each article). Generally speaking, sources of acid gain include: Sources of acid loss include: The body's acid–base balance is tightly regulated. Several buffering agents exist which reversibly bind hydrogen ions and impede any change in