Rh blood group system the clinical consequences of non-recognized "Rh factor", hemolytic transfusion reaction, and hemolytic disease of the newborn in its most severe form. It was recognized that the serum of the reported woman agglutinated with red blood cells of about 80% of the people although the then known blood groups, in particular ABO were matched. No name was given to this agglutinin when described. In 1940, Karl Landsteiner and Alexander S. Wiener made the connection to their earlier discovery, reporting a serum that also reacted with about 85% of different human red blood cells. In 1941, Group O: a patient of Dr.
Blood type personality theory methodology of his conclusions was unclear. Because of this, he was heavily criticized by the Japanese psychological community, although his books remain popular. His son, Toshitaka Nomi, continued to promote the theory with a series of books and by running the Institute of Blood Type Humanics. He later established the Human Science ABO Center for further research and publication in 2004. Some researchers believe blood types are associated with personality traits. Many medical surveys have been conducted, such as those for hormone secretion traits (DBH, COMT, MAO etc.), or the blood-type antigens in neurons, or the antigens expressed on surfaces