Internal combustion engine the atmosphere by the reaction of and volatile organic compounds in the presence of sunlight. Ground-level ozone is harmful to human health and the environment. Though the same chemical substance, ground-level ozone should not be confused with stratospheric ozone, or the ozone layer, which protects the earth from harmful ultraviolet rays. Carbon fuels contain sulfur and impurities that eventually produce sulfur monoxides (SO) and sulfur dioxide (SO) in the exhaust, which promotes acid rain. In the United States, nitrogen oxides, PM, carbon monoxide, sulphur dioxide, and ozone, are regulated as criteria air pollutants under the Clean Air Act to levels
Nitrogen dioxide poisoning glutathione reductase, an enzyme that catalyzes the reduction of glutathione disulfide (GSSG) to the sulfhydryl form glutathione (GSH), which is a critical molecule in resisting "oxidative stress" and maintaining the reducing environment of the cell. Exposure to nitrogen dioxide has a significant effect on the male reproductive system by inhibiting the production of Sertoli cell, a "nurse" cell of the testicles that is part of a seminiferous tubule and helps in the process of spermatogenesis. These effects consequently retard the production of sperm cell. The effects of nitrogen dioxide poisoning of female reproduction may be linked with the effects of