Laudanum his "archanum" or "laudanum", may or may not have contained opium. Paracelsus' laudanum was strikingly different from the standard laudanum of the 17th century and beyond, containing crushed pearls, musk, amber, and other substances. One researcher has documented that "Laudanum, as listed in the "London Pharmacopoeia" (1618), was a pill made from opium, saffron, castor, ambergris, musk and nutmeg". Laudanum remained largely unknown until the 1660s when English physician Thomas Sydenham (1624–1689) compounded a proprietary opium tincture that he also named laudanum, although it differed substantially from the laudanum of Paracelsus. In 1676 Sydenham published a seminal work, "Medical Observations
Old Crow Medicine Show join them on, that "the band inspired them to pick up the banjo and start their now famous country nights in London." Old Crow received the 2013 Trailblazer Award from the Americana Music Association. Current members of the band are: Former members of the band are: Old Crow Medicine Show Old Crow Medicine Show is an Americana string band based in Nashville, Tennessee, that has been recording since 1998. They were inducted into the Grand Ole Opry on September 17, 2013. Their ninth album, "Remedy", released in 2014, won the Grammy Award for Best Folk Album. The group's music has