Hippocampus anatomy These limbic structures include the hippocampus, cingulate cortex, olfactory cortex, and amygdala. Paul MacLean once suggested, as part of his triune brain theory, that the limbic structures constitute the neural basis of emotion. While most neuroscientists no longer believe in the concept of a unified "limbic system", these regions are highly interconnected and do interact with one another. Starting at the dentate gyrus and working inward along the S-curve of the hippocampus means traversing a series of narrow zones. The first of these, the dentate gyrus (DG), is actually a separate structure, a tightly packed layer of small granule cells
Intermediate-term memory in neurons. Unlike short-term memory and working memory, intermediate-term memory requires changes in translation to occur in order to function. While ITM requires only changes in translation, induction of long-term memory requires changes in transcription as well. The change from short-term memory to long-term memory is thought to dependent on CREB, which regulates transcription, but because ITM does not involve a change in transcription, it is thought to be independent of CREB activity. According to the definition of ITM proposed by Sutton "et al." in 2001, it disappears completely before long-term memory is induced. Intermediate-term memory Intermediate-term memory (ITM) is