Blood type transfusion can be considered safe as long as the serum of the recipient does not contain antibodies for the blood cell antigens of the donor. The "ABO system" is the most important blood-group system in human-blood transfusion. The associated anti-A and anti-B antibodies are usually "immunoglobulin M", abbreviated IgM, antibodies. ABO IgM antibodies are produced in the first years of life by sensitization to environmental substances such as food, bacteria, and viruses. The original terminology used by Karl Landsteiner in 1901 for the classification was A/B/C; in later publications "C" became "O". Type O is often called "0" ("zero", or
Jehovah's Witnesses and blood transfusions of outdated medical beliefs. Dissident Witnesses say the Society's use of Leviticus 17:12 to support its opposition to blood transfusions conflicts with its own teachings that Christians are not under the Mosaic law. Theologian Anthony Hoekema claims the blood prohibited in Levitical laws was not human, but animal. He cites other authors who support his view that the direction at Acts 15 to abstain from blood was intended not as an everlasting covenant but a means of maintaining a peaceful relationship between Jewish and Gentile Christians. He has described as "absurd literalism" the Witnesses' use of a scriptural prohibition on