ABO blood group system and likely predates human migration from Africa. The O01 allele is considered to predate the O02 allele. Some evolutionary biologists theorize that there are four main lineages of the ABO gene and that mutations creating type O have occurred at least three times in humans. From oldest to youngest, these lineages comprise the following alleles: "A101/A201/O09", "B101", "O02" and "O01". The continued presence of the O alleles is hypothesized to be the result of balancing selection. Both theories contradict the previously held theory that type O blood evolved first. It is possible that food and environmental antigens (bacterial, viral, or
Jehovah's Witnesses and blood transfusions who are Jehovah's Witness would not administer blood transfusions to fellow dedicated members. As to administering transfusions to non-members, "The Watchtower" stated that such a decision is "left to the Christian doctor's own conscience." In 1982, a "Watchtower" article declared that it would be wrong for a Witness to allow a leech to feed on his/her blood as part of a medical procedure, due to the sacredness of blood. In 1989 "The Watchtower" stated, "Each individual must decide" whether to accept hemodilution and autologous blood salvage (cell saver) procedures. In 1990, a brochure entitled "How Can Blood Save Your Life?"