Acetonitrile formulations for nail polish remover, despite its toxicity. At least two cases have been reported of accidental poisoning of young children by acetonitrile-based nail polish remover, one of which was fatal. Acetone and ethyl acetate are often preferred as safer for domestic use, and acetonitrile has been banned in cosmetic products in the European Economic Area since March 2000. In common with other nitriles, acetonitrile can be metabolised in microsomes, especially in the liver, to produce hydrogen cyanide, as was first shown by Pozzani "et al." in 1959. The first step in this pathway is the oxidation of acetonitrile to
Antipyrine and benzocaine ear drops Antipyrine and benzocaine ear drops Antipyrine and benzocaine ear drops is a medication for the treatment of ear pain caused by otitis media. It combines antipyrine, a pain reliever, benzocaine, a numbing agent to treat ear pain, and hydroxyquinoline sulfate, an antiseptic. It is sold as Auralgan, Aurodex, Auroto, among other brands, and is abbreviated as A/B otic drops. A/B otic drops is indicated for ear pain caused by otitis media. It is used every 2–3 hours as needed for pain. A/B otic drops is also indicated for the removal of excessive or impacted cerumen. To clear cerumen, it is