Acid–base reaction liquid ammonia are similar to the reactions in water: Nitric acid can be a base in liquid sulfuric acid: The unique strength of this definition shows in describing the reactions in aprotic solvents; for example, in liquid : Because the solvent system definition depends on the solute as well as on the solvent itself, a particular solute can be either an acid or a base depending on the choice of the solvent: is a strong acid in water, a weak acid in acetic acid, and a weak base in fluorosulfonic acid; this characteristic of the theory has been seen as
Acid–base reaction chemistry. The ECW model is quantitative model that describes and predicts the strength of Lewis acid base interactions, −Δ"H". The model assigned "E" and "C" parameters to many Lewis acids and bases. Each acid is characterized by an "E" and a "C". Each base is likewise characterized by its own "E" and "C". The "E" and "C" parameters refer, respectively, to the electrostatic and covalent contributions to the strength of the bonds that the acid and base will form. The equation is The "W" term represents a constant energy contribution for acid–base reaction such as the cleavage of a dimeric