ABO blood group system alleles in white individuals of the ABO gene that produce one's blood type: The same study also identified 18 rare alleles, which generally have a weaker glycosylation activity. People with weak alleles of A can sometimes express anti-A antibodies, though these are usually not clinically significant as they do not stably interact with the antigen at body temperature. Cis AB is another rare variant, in which A and B genes are transmitted together from a single parent. The distribution of the blood groups A, B, O and AB varies across the world according to the population. There are also variations
Jehovah's Witnesses and blood transfusions place patients at heightened risk for reduced long-term survival." The study also stated that "Survival estimates of Witnesses were 86%, 69%, 51%, and 34% at 5, 10, 15, and 20 years after surgery, respectively, vs 74%, 53%, 35%, and 23% among non-Witnesses who received transfusions." Bloodless medical and surgical techniques have limitations, and surgeons say the use of various allogeneic blood products and pre-operative autologous blood transfusion are appropriate standards of care for certain patient presentations. The Watch Tower Society states that in medical emergencies where blood transfusions seem to be the only available way to save a life, Jehovah's