Zeotropic mixture harmful effects that hydrochlorofluorocarbons (HCFC) and chlorofluorocarbons (CFC) have on the ozone layer and global warming. Researchers have focused on using new mixtures that have the same properties as past refrigerants to phase out harmful halogenated substances, in accordance to the Montreal Protocol and Kyoto Protocol. For example, researchers found that zeotropic mixture R-404A can replace R-12, a CFC, in household refrigerators. However, there are some technical difficulties for using zeotropic mixtures. This includes leakages, as well as the high temperature glide associated with substances of different boiling points, though the temperature glide can be matched to the temperature difference
Wireless Application Protocol protocol design was appropriate. Some have suggested that the bandwidth-sparing simple interface of Gopher would be a better match for mobile phones and Personal digital assistants (PDAs). The initial design of WAP specifically aimed at protocol independence across a range of different protocols (SMS, IP over PPP over a circuit switched bearer, IP over GPRS, etc.). This has led to a protocol considerably more complex than an approach directly over IP might have caused. Most controversial, especially for many from the IP side, was the design of WAP over IP. WAP's transmission layer protocol, WTP, uses its own retransmission mechanisms