Nitrous oxide its concentration has increased 15% since 1750, control of nitrous oxide is considered part of efforts to curb greenhouse gas emissions. A 2008 study by Nobel Laureate Paul Crutzen suggests that the amount of nitrous oxide release attributable to agricultural nitrate fertilizers has been seriously underestimated, most of which presumably, would come under soil and oceanic release in the Environmental Protection Agency data. Nitrous oxide also has been implicated in thinning of the ozone layer. A new study suggests that emission currently is the single most important ozone-depleting substance (ODS) emission and is expected to remain the largest throughout the
Nitrous oxide because has a very short duration under normal circumstances, it is less likely to be neurotoxic than other NMDA antagonists. Indeed, in rodents, short-term exposure results in only mild injury that is rapidly reversible, and neuronal death occurs only after constant and sustained exposure. Nitrous oxide also may cause neurotoxicity after extended exposure because of hypoxia. This is especially true of non-medical formulations such as whipped-cream chargers (also known as "whippets" or "nangs"), which never contain oxygen, since oxygen makes cream rancid. Additionally, nitrous oxide depletes vitamin B levels. This can cause serious neurotoxicity if the user has preexisting vitamin