Hydrazoic acid was originally prepared by the reaction of aqueous hydrazine with nitrous acid. Other oxidizing agents, such as hydrogen peroxide, nitrosyl chloride, trichloramine or nitric acid, can also be used. In its properties hydrazoic acid shows some analogy to the halogen acids, since it forms poorly soluble (in water) lead, silver and mercury(I) salts. The metallic salts all crystallize in the anhydrous form and decompose on heating, leaving a residue of the pure metal. It is a weak acid (p"K" = 4.75.) Its heavy metal salts are explosive and readily interact with the alkyl iodides. Azides of heavier alkali metals (excluding
Acid perfusion test hoarseness, chronic cough, then 24 hr pH monitoring should be considered. Acid perfusion test Acid perfusion test, also called the Bernstein test, is a test done to reproduce the pain when the lower esophagus is irrigated with an acid solution in people with GERD (gastroesophageal reflux disease). There will be a negative result in normal people, but a false positive reading may be seen in up to 15% of people. Bernstein test is obsolete nowadays. 24 hour pH monitoring is the gold standard for GERD. However, the initial management is with proton pump inhibitors. If the patient does not respond