Laudanum his "archanum" or "laudanum", may or may not have contained opium. Paracelsus' laudanum was strikingly different from the standard laudanum of the 17th century and beyond, containing crushed pearls, musk, amber, and other substances. One researcher has documented that "Laudanum, as listed in the "London Pharmacopoeia" (1618), was a pill made from opium, saffron, castor, ambergris, musk and nutmeg". Laudanum remained largely unknown until the 1660s when English physician Thomas Sydenham (1624–1689) compounded a proprietary opium tincture that he also named laudanum, although it differed substantially from the laudanum of Paracelsus. In 1676 Sydenham published a seminal work, "Medical Observations
Old Crow Medicine Show multiple times at other major festivals, e.g., Bonnaroo Music Festival, MerleFest, Telluride Bluegrass Festival, Hardly Strictly Bluegrass Festival, and Newport Folk Festival. They have made frequent guest appearances on "A Prairie Home Companion" with Garrison Keillor. The group received the 2013 Trailblazer Award from the Americana Music Association, performing at the Americana Honors & Awards Show. Publishing administrator Downtown Music Publishing represents the works of Old Crow Medicine Show. Ketch Secor and Critter Fuqua first met in the seventh grade in Harrisonburg, Virginia and began playing music together. They performed open mics at the Little Grill diner, as did Robert