ABO blood group system in blood type distribution within human subpopulations. In the UK, the distribution of blood type frequencies through the population still shows some correlation to the distribution of placenames and to the successive invasions and migrations including Norsemen, Danes, Saxons, Celts, and Normans who contributed the morphemes to the placenames and the genes to the population. The two common O alleles, O01 and O02, share their first 261 nucleotides with the group A allele A01. However, unlike the group A allele, a guanosine base is subsequently deleted. A premature stop codon results from this frame-shift mutation. This variant is found worldwide,
Rh blood group system factor is not identical to the rhesus monkey factor; but by then, "Rhesus Group" and like terms were already in widespread, worldwide use. Thus, notwithstanding it is a misnomer, the term survives (e.g. "rhesus blood group system", and the obsolete terms "rhesus factor", " rhesus positive", and "rhesus negative" - all three which actually refer specifically and "only" to the Rh D factor; and, thus, are misleading when unmodified). Contemporary practice is to use "Rh" as a term of art instead of "Rhesus"; viz. "Rh Group," "Rh factors," "Rh D," etc. The first rhesus blood type was discovered in 1937