Irish Blood Transfusion Service Service. The frequency of blood groups in Ireland is as follows: It is important that the IBTS collects enough O Rh D positive blood as almost half the population are that blood type. Donors with O Rh D negative are known as universal donors. Their blood can be transfused to patients of any other blood group in an emergency or if the patient's own blood group is unavailable. Because any patient can receive O Rh D negative blood, the IBTS need to have extra O Rh D negative blood available at all times. The service depends entirely on voluntary donations
ABO blood group system of these enzymes was correlated to malignant bladder and oral epithelia. Furthermore, the expression of ABO blood group antigens in normal human tissues is dependent the type of differentiation of the epithelium. In most human carcinomas, including oral carcinoma, a significant event as part of the underlying mechanism is decreased expression of the A and B antigens. Several studies have observed that a relative down-regulation of GTA and GTB occurs in oral carcinomas in association with tumor development. More recently, a genome wide association study (GWAS) has identified variants in the ABO locus associated with susceptibility to pancreatic cancer. A