Blood type diet type diet hypothesis and no clinical evidence that it improves health. Peter J. D'Adamo, a naturopath, is the most prominent proponent of blood type diets. Luiz C. de Mattos and Haroldo W. Moreira point out that assertions made by proponents of blood type diets that the O blood type was the first human blood type requires that the O gene have evolved before the A and B genes in the ABO locus; phylogenetic networks of human and non-human ABO alleles show that the A gene was the first to evolve. They argue that it would be extraordinary, from the perspective
ABO blood group system group B blood agglutinates with group A. Group C blood is different in that it agglutinates with both A and B. This was the discovery of blood groups for which Landsteiner was awarded the Nobel Prize in Physiology or Medicine in 1930. In his paper, he called the specific blood group interactions as isoagglutination, and also introduced the concept of agglutinins (antibodies), which is the actual basis of antigen-antibody reaction in ABO system. He asserted: Thus, he discovered two antigens (agglutinogens A and B) and two antibodies (agglutinins - anti-A and anti-B). His third group (C) indicated absence of both