Patent medicine the patent medicines, some of their makers began replacing the opium tincture laudanum with acetanilide, a particularly toxic non-steroidal anti-inflammatory drug with analgesic as well as antipyretic properties that had been introduced into medical practice under the name "Antifebrin" by A. Cahn and P. Hepp in 1886. But this ingredient change probably killed more of the nostrum's users than the original narcotics did, since acetanilide not only caused an alarming cyanosis due to methemoglobinemia but was later discovered to cause liver and kidney damage. The occasional reports of acetanilide-induced cyanosis prompted the search for supposedly less toxic aniline derivatives, such
Drug culture S. Thompson's "Fear and Loathing in Las Vegas" employs multiple drug use as a major theme and provides an example of the drug culture of the 1960s. Alcoholic beverages contain ethanol (simply called alcohol). Ethanol is a psychoactive drug primarily found in alcoholic beverages. Alcohol is one of the most commonly abused drugs in the world (Metropol, 1996) often used for self-medication, and as recreational drug use. Cannabis has been used in the ancient past in places such as ancient India, Romania, Egypt, and Mesopotamia. It was often used as medicine or for hemp, its main route of consumption was