Amygdala Amygdala The amygdala (; plural: amygdalae; also "corpus amygdaloideum"; Latin from Greek, , "", 'Almond', 'tonsil') is one of two almond-shaped clusters of nuclei located deep and medially within the temporal lobes of the brain in complex vertebrates, including humans. Shown in research to perform a primary role in the processing of memory, decision-making and emotional responses (including fear, anxiety, and aggression), the amygdalae are considered part of the limbic system. The regions described as amygdala nuclei encompass several structures with distinct connectional and functional characteristics in humans and other animals. Among these nuclei are the basolateral complex, the cortical
Long-term impact of alcohol on the brain help had relapsed, and 39% of those who tried to remain abstinent with help had relapsed. Long-term, stable consequences of chronic alcohol abuse are thought to be due to stable alterations of gene expression resulting from epigenetic changes within particular regions of the brain. For example, in rats exposed to alcohol for up to 5 days, there was an increase in histone 3 lysine 9 acetylation in the pronociceptin promoter in the brain amygdala complex. This acetylation is an activating mark for pronociceptin. The nociceptin/nociceptin opioid receptor system is involved in the reinforcing or conditioning effects of alcohol. Long-term impact