Nitrous oxide its concentration has increased 15% since 1750, control of nitrous oxide is considered part of efforts to curb greenhouse gas emissions. A 2008 study by Nobel Laureate Paul Crutzen suggests that the amount of nitrous oxide release attributable to agricultural nitrate fertilizers has been seriously underestimated, most of which presumably, would come under soil and oceanic release in the Environmental Protection Agency data. Nitrous oxide also has been implicated in thinning of the ozone layer. A new study suggests that emission currently is the single most important ozone-depleting substance (ODS) emission and is expected to remain the largest throughout the
Sulfur dioxide are mediated via ATP-dependent calcium channels and L-type ("dihydropyridine") calcium channels. Endogenous sulfur dioxide is also a potent antiinflammatory, antioxidant and cytoprotective agent. It lowers blood pressure and slows hypertensive remodeling of blood vessels, especially thickening of their intima. It also regulates lipid metabolism. Endogenous sulfur dioxide also diminishes myocardial damage, caused by isoproterenol adrenergic hyperstimulation, and strengthens the myocardial antioxidant defense reserve. Being easily condensed and possessing a high heat of evaporation, sulfur dioxide is a candidate material for refrigerants. Prior to the development of chlorofluorocarbons, sulfur dioxide was used as a refrigerant in home refrigerators. Sulfur dioxide is