Acid–base reaction liquid ammonia are similar to the reactions in water: Nitric acid can be a base in liquid sulfuric acid: The unique strength of this definition shows in describing the reactions in aprotic solvents; for example, in liquid : Because the solvent system definition depends on the solute as well as on the solvent itself, a particular solute can be either an acid or a base depending on the choice of the solvent: is a strong acid in water, a weak acid in acetic acid, and a weak base in fluorosulfonic acid; this characteristic of the theory has been seen as
Acid–base homeostasis Thus, by manipulating firstly the concentration of the weak acid, and secondly that of its conjugate base, the pH of the extracellular fluid (ECF) can be adjusted very accurately to the correct value. The bicarbonate buffer, consisting of a mixture of carbonic acid (HCO) and a bicarbonate () salt in solution, is the most abundant buffer in the extracellular fluid, and it is also the buffer whose acid to base ratio can be changed very easily and rapidly. An acid–base imbalance is known as acidaemia when the acidity is high, or alkalaemia when the acidity is low. The pH of