Acetonitrile formulations for nail polish remover, despite its toxicity. At least two cases have been reported of accidental poisoning of young children by acetonitrile-based nail polish remover, one of which was fatal. Acetone and ethyl acetate are often preferred as safer for domestic use, and acetonitrile has been banned in cosmetic products in the European Economic Area since March 2000. In common with other nitriles, acetonitrile can be metabolised in microsomes, especially in the liver, to produce hydrogen cyanide, as was first shown by Pozzani "et al." in 1959. The first step in this pathway is the oxidation of acetonitrile to
Pear drop product from pear juice concentrate is sometimes used. The largest pear drop in the world is housed at Stockley's Sweets in Oswaldtwistle Mills in Oswaldtwistle, Lancashire, England. In 2009 a survey of 4,000 adults found that pear drops were the fourteenth most popular sweet in the United Kingdom. Pear drop A pear drop is a British boiled sweet made from sugar and flavourings. The classic pear drop is a combination of half pink and half yellow in a pear-shaped drop about the size of a thumbnail, although they are more commonly found in packets containing separate yellow drops and pink