Trifluoroacetic acid Trifluoroacetic acid Trifluoroacetic acid (TFA) is an organofluorine compound with the chemical formula CFCOH. It is a structural analogue of acetic acid with all three of the acetyl group’s hydrogen atoms replaced by fluorine atoms and is a colorless liquid with a vinegar like odor. TFA is a stronger acid than acetic acid, having an acid ionisation constant that is approximately 34,000 times higher, as the highly electronegative fluorine atoms and consequent electron-withdrawing nature of the trifluoromethyl group weakens the oxygen-hydrogen bond (allowing for greater acidity) and stabilises the anionic conjugate base. TFA is widely used in organic chemistry for
Orthocarbonic acid to be observed. However, theoretical studies suggest that NaCO might be stable. The tetravalent moiety CO is found in stable organic compounds; they are formally esters of orthocarbonic acid, and therefore are called orthocarbonates. For example, Tetraethoxymethane can be prepared by the reaction between chloropicrin and sodium ethoxide in ethanol. Polyorthocarbonates are stable polymers that might have applications in absorbing organic solvents in waste treatment processes, or in dental restorative materials. The explosive trinitroethylorthocarbonate possesses a orthocarbonate core. Orthocarbonic acid Orthocarbonic acid (methanetetrol) is the name given to a hypothetical compound with the chemical formula HCO or C(OH). Its molecular