Metered-dose inhaler stringent set of criteria, they must: In the early days of MDIs the most commonly used propellants were the chlorofluorocarbons CFC-11, CFC-12 and CFC-114. In 2008 the Food and Drug Administration announced that inhalers using chlorofluorocarbons as a propellant, such as Primatene Mist, could no longer be manufactured or sold as of 2012. This followed from the U.S. decision to agree to the 1987 Montreal Protocol on Substances that Deplete the Ozone Layer. Phospholipids are important natural surfactant lipids used in enhancing penetration and bioavailability. Phospholipids act by reducing the high surface tension forces at the air-water interface within the
Program and System Information Protocol Program and System Information Protocol The Program and System Information Protocol (PSIP) is the MPEG (a video and audio industry group) and privately defined program-specific information originally defined by General Instrument for the DigiCipher 2 system and later extended for the ATSC digital television system for carrying metadata about each channel in the broadcast MPEG transport stream of a television station and for publishing information about television programs so that viewers can select what to watch by title and description. PSIP defines virtual channels and content ratings, as well as electronic program guides with titles and (optionally) descriptions to be