Acetonitrile formulations for nail polish remover, despite its toxicity. At least two cases have been reported of accidental poisoning of young children by acetonitrile-based nail polish remover, one of which was fatal. Acetone and ethyl acetate are often preferred as safer for domestic use, and acetonitrile has been banned in cosmetic products in the European Economic Area since March 2000. In common with other nitriles, acetonitrile can be metabolised in microsomes, especially in the liver, to produce hydrogen cyanide, as was first shown by Pozzani "et al." in 1959. The first step in this pathway is the oxidation of acetonitrile to
Science of smells Science of smells The odorology or science of smells is a technology used mainly in criminology for judicial identification. The technology is based on the analysis of smells by dogs notably to merge the criminals or to identify the smell of objects (explosives, drugs). Olfaction of dogs is used for a long time by the police (location of drug, of explosives, of weapon, body of missing persons, criminals' identification) or the services of rescue (bodies buried under avalanches). From 1910, a dog handler Friedo Schmidt describes in his book Verbrecherspur und Polizeihund («The criminal links and the police dog») how