Metered-dose inhaler stringent set of criteria, they must: In the early days of MDIs the most commonly used propellants were the chlorofluorocarbons CFC-11, CFC-12 and CFC-114. In 2008 the Food and Drug Administration announced that inhalers using chlorofluorocarbons as a propellant, such as Primatene Mist, could no longer be manufactured or sold as of 2012. This followed from the U.S. decision to agree to the 1987 Montreal Protocol on Substances that Deplete the Ozone Layer. Phospholipids are important natural surfactant lipids used in enhancing penetration and bioavailability. Phospholipids act by reducing the high surface tension forces at the air-water interface within the
1987 (What the Fuck Is Going On?) Run-D.M.C. type of old-school rapping"; and "The Penguin Price Guide for Record & CD Collectors" called "1987" an "entirely brilliant example of the art of disc-jockey-as-producer". Giving another retrospective review from across the Atlantic, "Trouser Press" described "1987" as "energetic" and "a loopy dance album that isn't unlike a lot of sampled records, but proceeds from an entirely different cultural understanding." Bill Drummond and Jimmy Cauty were responsible for the concept and production of "1987", its lyrics and the TR-808 beatbox rhythms. Drummond provided rap, and an additional rapper introduced as 'Chike' appears on "Don't Take Five (Take What You