Laudanum adult who is not habituated to opiates. This represents the equivalent of between two to three teaspoons () of opium tincture. Suicide by laudanum was not uncommon in the mid-19th century. Prudent medical judgment necessitates toward dispensing very small quantities of opium tincture in small dropper bottles or in pre-filled syringes to reduce the risk of intentional or accidental overdose. In the United States, opium tincture contains 10 mg per mL of anhydrous morphine. By contrast, opium tincture's weaker cousin, paregoric, also confusingly known as "camphorated tincture of opium", is 1/25th the strength of opium tincture, containing only 0.4 mg
Desensitization (medicine) include: Desensitization (medicine) In medicine, desensitization is a method to reduce or eliminate an organism's negative reaction to a substance or stimulus. In pharmacology, "drug desensitization" is equivalent to drug tolerance, though the latter term refers to the more general concept of subjects' reactions (positive or negative) to a drug reducing following its repeated use. For example, if a person with diabetes mellitus has a bad allergic reaction to taking a full dose of beef insulin, the person is given a very small amount of the insulin at first, so small that the person has no adverse reaction or very