Quick-Step Floors the Tour de France, taking two stage wins. Bettini defended his world championship in Stuttgart. In 2008 Gert Steegmans took the final stage of the 2008 Tour de France on the Champs-Élysées. Paolo Bettini retired after the world championship in Varese. In both 2008 and 2009 Stijn Devolder took the Tour of Flanders and Tom Boonen, Paris–Roubaix. After two seasons of disappointment, a resurgent Omega Pharma–Quick-Step and Tom Boonen, took four major Spring classics victories, including the four cobblestone courses E3 Harelbeke, Gent–Wevelgem, Tour of Flanders, Paris–Roubaix. In October 2012, the team fired their veteran rider Levi Leipheimer after he
THC-O-phosphate ester is made by reacting THC with phosphoryl chloride using pyridine as a solvent, following by quenching with water to produce THC phosphate ester. In the original research the less active but more stable isomer Δ8THC was used, but the same reaction scheme could be used to make the phosphate ester of the more active isomer Δ9THC. THC-O-phosphate THC-"O"-phosphate is a water-soluble organophosphate ester derivative of THC, which functions as a metabolic prodrug for THC itself. It was invented in 1978 in an attempt to get around the poor water solubility of THC and make it easier to inject for