History of alcoholic drinks hawthorn berries, honey, and rice was being produced in 7000–6650 BC. The results of this analysis were published in December 2004. This is approximately the time when barley beer and grape wine were beginning to be made in the Middle East. The earliest firm evidence of wine production dates back to 6000 BC in Georgia . Evidence of alcoholic beverages has also been found dating from 3150 BC in ancient Egypt, 3000 BC in Babylon, 2000 BC in pre-Hispanic Mexico, and 1500 BC in Sudan. The medicinal use of alcohol was mentioned in Sumerian and Egyptian texts dating from about
Alcoholic drink and fat oxidation. Ethanol is directly processed in the liver to acetyl CoA, the same intermediate product as in glucose metabolism. Because ethanol is mostly metabolized and consumed by the liver, chronic excessive use can lead to fatty liver. This leads to a chronic inflammation of the liver and eventually alcoholic liver disease. The average number of people who drink was 39% for males and 25% for females (2.4 billion people in total). Females on average drink 0.7 drinks per day while males drink 1.7 drinks per day. The rates of drinking varies significantly in different areas of the world.