Pleiotropy correlations and responses to selection most often exemplify pleiotropy. Pleiotropic traits had been previously recognized in the scientific community but had not been experimented on until Gregor Mendel's 1866 pea plant experiment. Mendel recognized that certain pea plant traits (seed coat color, flower color, and axial spots) seemed to be inherited together; however, their correlation to a single gene has never been proven. The term "pleiotropie" was first coined by Ludwig Plate in his Festschrift, which was published in 1910. He originally defined pleiotropy as occurring when "several characteristics are dependent upon ... [inheritance]; these characteristics will then always appear
Genetics and the Origin of Species to identify that some populations of this species did not have identical sets of genes. Dobzhansky used experimental breeding in laboratories and gardens, and also surveys related to species in nature to help support aspects of organic evolution. The data in his book show the different genetic mutations and chromosomal changes that were observed. These experiments are vital to this book because they illustrate a transition from the laboratory to the greater field of genetics. "Drosophila" enabled researchers to gain a deeper understanding of how scientific knowledge about heredity has expanded and contributed to other areas of biology. By focusing