Pleiotropy correlations and responses to selection most often exemplify pleiotropy. Pleiotropic traits had been previously recognized in the scientific community but had not been experimented on until Gregor Mendel's 1866 pea plant experiment. Mendel recognized that certain pea plant traits (seed coat color, flower color, and axial spots) seemed to be inherited together; however, their correlation to a single gene has never been proven. The term "pleiotropie" was first coined by Ludwig Plate in his Festschrift, which was published in 1910. He originally defined pleiotropy as occurring when "several characteristics are dependent upon ... [inheritance]; these characteristics will then always appear
Genetics of aggression middle-age period) were more violent and aggressive in their attacks on other mice. Selective breeding is a quick way to select for specific traits and see those selected traits within a few generations of breeding. These characteristics make selective breeding an important tool in the study of genetics and aggressive behavior. Mice are often used as a model for human genetic behavior since mice and humans have homologous genes coding for homologous proteins that are used for similar functions at some biological levels. Mice aggression studies have led to some interesting insight in human aggression. Using reverse genetics, the DNA