Pencil sharpener pencil in position, although they then sharpen them to the usual conical point as for a round pencil, abandoning some distinctive aspects of the carpenter's pencil. Sharpeners with a single blade for use on wax crayons are available, and sometimes included in boxes of crayons. These often have plastic blades, which are adequate for the soft wax. Mechanical pencils dispense the graphite lead progressively during use and thus do not require sharpening; such pencils are sometimes called "self-sharpening". A type of mechanical pencil has a rotating gear mechanism which rotates the lead slightly every time the lead is lifted off
Lead poisoning affected by lead toxicity to varying degrees depending on species. Animals experience many of the same effects of lead exposure as humans do, such as abdominal pain, peripheral neuropathy, and behavioral changes such as increased aggression. Much of what is known about human lead toxicity and its effects is derived from animal studies. Animals are used to test the effects of treatments, such as chelating agents, and to provide information on the pathophysiology of lead, such as how it is absorbed and distributed in the body. Farm animals such as cows and horses as well as pet animals are also