Unit of selection and Confirmation of Evolutionary Theory" provides a basic "philosophical" introduction to the debate. Below, cases of selection at the genic, cellular, individual and group level from within the multi-level selection perspective are presented and discussed. George C. Williams in his influential book "Adaptation and Natural Selection" was one of the first to present a gene-centered view of evolution with the gene as the unit of selection, arguing that a unit of selection should exhibit a high degree of permanence. Richard Dawkins has written several books popularizing and expanding the idea. According to Dawkins, genes cause phenotypes and a gene is
Alternatives to evolution by natural selection through a population when they were beneficial, helped by natural selection. This represented the germ of the modern synthesis, and the beginning of the end for mutationism as an evolutionary force. Contemporary biologists accept that mutation and selection both play roles in evolution; the mainstream view is that while mutation supplies material for selection in the form of variation, all non-random outcomes are caused by natural selection. Masatoshi Nei argues instead that the production of more efficient genotypes by mutation is fundamental for evolution, and that evolution is often mutation-limited. The endosymbiotic theory implies rare but major events of saltational