Eutrophication and development, pollution from septic systems and sewers, sewage sludge spreading, and other human-related activities increase the flow of both inorganic nutrients and organic substances into ecosystems. Elevated levels of atmospheric compounds of nitrogen can increase nitrogen availability. Phosphorus is often regarded as the main culprit in cases of eutrophication in lakes subjected to "point source" pollution from sewage pipes. The concentration of algae and the trophic state of lakes correspond well to phosphorus levels in water. Studies conducted in the Experimental Lakes Area in Ontario have shown a relationship between the addition of phosphorus and the rate of eutrophication.
Eutrophication for around one third of the ocean's external (non-recycled) nitrogen supply, and up to 3% of the annual new marine biological production. It has been suggested that accumulating reactive nitrogen in the environment may prove as serious as putting carbon dioxide in the atmosphere. Terrestrial ecosystems are subject to similarly adverse impacts from eutrophication. Increased nitrates in soil are frequently undesirable for plants. Many terrestrial plant species are endangered as a result of soil eutrophication, such as the majority of orchid species in Europe. Meadows, forests, and bogs are characterized by low nutrient content and slowly growing species adapted to