Grand Erg Occidental Grand Erg Occidental The Grand Erg Occidental (, al-ʿIrq al-Gharbī al-Kabīr), (also known as the Western Sand Sea) is the second largest erg in northern Algeria after the Grand Erg Oriental. It covers an area of approximately . The sand dunes in the erg are formed by the wind, and can be up to high. Certain crescent-shaped dunes, known as barchans, are actually mobile; the wind can push these dunes as much as 20 to 30 m (65-100 ft) in one year. It is a desert natural region that receives less than 50 mm (1,96 in) of rainfall per year.
ERG (gene) TLS/FUS in Ewing's sarcoma and acute myeloid leukemias respectively and function as transcriptional activators. ERG and its fusion proteins EWS-ERG and TLS/FUS-ERG inhibit apoptosis. "ERG" can fuse with TMPRSS2 protein to form an oncogenic fusion gene that is commonly found in human prostate cancer, especially in hormone-refractory prostate cancer. This suggests that "ERG" overexpression may contribute to development of androgen-independence in prostate cancer through disruption of androgen receptor signaling. The fusion gene is critical to the progression of cancer because it inhibits the androgen receptor expression and it binds and inhibits androgen receptors already present in the cell. Essentially TMPRSS2-ERG