Catgut suture treatment produces roughly twice the stitch-holding time of plain catgut, but greater tissue inflammation occurs. Full tensile strength is extended to 18–21 days. It is brown rather than straw-colored, and has improved smoothness due to the dry presentation of the thread (plain catgut is wet). It is otherwise similar to plain catgut. Fast catgut suture is heat-treated to give even more rapid absorption in the body. The first known absorbable sutures were made of the intestines of sheep. The manufacturing process was similar to that of natural musical strings for violins and guitar, and also of natural strings for tennis
Musical instrument first device considered a musical instrument is disputed. The oldest object that some scholars refer to as a musical instrument, a simple flute, dates back as far as 67,000 years. Some consensus dates early flutes to about 37,000 years ago. However, most historians believe that determining a specific time of musical instrument invention is impossible due to the subjectivity of the definition and the relative instability of materials used to make them. Many early musical instruments were made from animal skins, bone, wood, and other non-durable materials. Musical instruments developed independently in many populated regions of the world. However, contact