Biodegradable polymer which, edible films have gained more attention due to their environmentally-friendly characteristics, vast variety and availability, non-toxicity, and low cost. Biodegradable polymers have a long history, and since many are natural products, the precise timeline of their discovery and use cannot be accurately traced. One of the first medicinal uses of a biodegradable polymer was the catgut suture, which dates back to at least 100 AD. The first catgut sutures were made from the intestines of sheep, but modern catgut sutures are made from purified collagen extracted from the small intestines of cattle, sheep, or goats. The concept of synthetic
Catgut Before 1900, the best strings for musical instruments were reputedly from Italy. Musicians believed the best were from Naples, though Rome and other Italian cities also produced excellent strings. Today high quality gut strings are produced mostly in Italy, Germany, and the United States. They are also made elsewhere, for example in India and Morocco, for local use. Catgut suture was once a widely used material in surgical settings. There is debate about whether to continue using catgut in a medical setting, since cotton is usually cheaper and wounds closed with either cotton or synthetic threads are less prone to