Blepharitis of normal patients. Staphylococcal blepharitis may start in childhood and continue into adulthood. It is commonly recurrent and it requires special medical care. The prevalence of Staphylococcus aureus in the conjunctival sac and on the lid margin varies among countries, likely due to differences in climate and environment. Seborrheic blepharitis is characterized by less inflammation than Staphylococcal blepharitis; however, it causes more excess oil or greasy scaling. Meibomian Gland Dysfunction is a result of abnormalities of the meibomian glands and altered secretion meibum, which plays an imperative role in lagging the evaporation of tear films and smoothing of the tear
Dental sealant that resin could be bonded to enamel through acid etching, increasing adhesion whilst also creating an improved marginal integrity of resin restorative material. It was this bonding system that lead to the future successful creation of fissure sealants. In 1966, E.I. Cueto created the first sealant material, which was methyl cyanoacrylate. However, this material was susceptible to bacterial breakdown over time, therefore was not an acceptable sealing material. Bunonocore made further advances in 1970 by developing bisphenol-a glycidyl dimethacrylate, which is a viscous resin commonly known as BIS-GMA. This material was used as the basis for many resin-based sealant/composite material