Zebrafish their larval stages. In 2011, the British Heart Foundation ran an advertising campaign publicising its intention to study the applicability of this ability to humans, stating that it aimed to raise £50 million in research funding. Zebrafish have also been found to regenerate photoreceptor cells and retinal neurons following injury, which has been shown to be mediated by the dedifferentiation and proliferation of Müller glia. Researchers frequently amputate the dorsal and ventral tail fins and analyze their regrowth to test for mutations. It has been found that histone demethylation occurs at the site of the amputation, switching the zebrafish's cells
Tiktaalik Tiktaalik Tiktaalik is a monospecific genus of extinct sarcopterygian (lobe-finned fish) from the late Devonian period, about 375 MYA (million years ago), having many features akin to those of tetrapods (four-legged animals). Unearthed in Arctic Canada, Tiktaalik is technically a fish, complete with scales and gills - but it has the flattened head of a crocodile and unusual fins. Its fins have thin ray bones for paddling like most fishes', but they also have sturdy interior bones that would have allowed Tiktaalik to prop itself up in shallow water and use its limbs for support as most four-legged animals do.