Meibomian gland Meibomian gland The Meibomian glands (often written with a small "m" and also called tarsal glands) are a holocrine type of exocrine glands, at the rim of the eyelids inside the tarsal plate, responsible for the supply of meibum, an oily substance that prevents evaporation of the eye's tear film. Meibum prevents tear spillage onto the cheek, trapping tears between the oiled edge and the eyeball, and makes the closed lids airtight. There are approximately 50 glands on the upper eyelids and 25 glands on the lower eyelids. Dysfunctional meibomian glands often cause dry eyes, one of the more common
Sebaceous gland due to heightened levels of androgens. Sebaceous glands secrete the oily, waxy substance called "sebum" () that is made of triglycerides, wax esters, squalene, and metabolites of fat-producing cells. Sebum waterproofs and lubricates the skin and hair of mammals. Sebaceous secretions in conjunction with apocrine glands also play an important thermoregulatory role. In hot conditions, the secretions emulsify the sweat produced by the eccrine glands and this produces a sheet of sweat that is not readily lost in drops of sweat. This is of importance in delaying dehydration. In colder conditions, the nature of sebum becomes more lipid and in