Grand Erg Oriental follow the wind's direction. There are other types of dunes, as well as "complex" dunes. Saharan winds are also known to clear an area of sand altogether, leaving bare rock (hamada) or gravel (reg). The "Grand Erg Oriental" is accessible overland by an Algerian road, which goes south from Constantine. It passes through the Aurès mountains, then salt lakes by the city of Biskra. Next the road skirts the western edge of the erg. After about 500 km. in all, it reaches the ancient oasis of Ourgla [Wargla]. Since late antiquity Wargla was a stop for the Saharan trade, being
ERG (gene) in mature lymphocytes (types of white blood cells). Therefore, ERG may act as a regulator of differentiation of early hematopoietic cells. The Mld2 mutation, generated through an ENU mutagenesis screen, was the first non-functional allele of "Erg". Homozygous Mld2 is embryonic lethal at day 13.5. Adult mice heterozygous for the Mld2 mutation have hematopoietic stem cell defects. This means that when the ERG gene was not actively transcribed and the ERG protein produced, a mouse's hematopoietic cells were unable to function properly. Since ERG is important to the ability of the hematopoietic cells to function and self-renew, there may be