History of the bicycle fashion of the day made the "ordinary" bicycle inaccessible. Queen Victoria owned Starley's "Royal Salvo" tricycle, though there is no evidence she actually rode it. Although French and English inventors modified the velocipede into the high-wheel bicycle, the French were still recovering from the Franco-Prussian war, so English entrepreneurs put the high-wheeler on the English market, and the machine became very popular there, Coventry, Oxford, Birmingham and Manchester being the centers of the English bicycle industry (and of the arms or sewing machine industries, which had the necessary metalworking and engineering skills for bicycle manufacturing, as in Paris and St.
Urs A. Meyer to the molecular mechanism by which drugs activate transcription factors such as nuclear receptors and thereby regulate the expression of drug metabolizing enzymes and drug transporters. Urs A. Meyer Urs Albert Meyer is a Swiss physician-scientist and clinical pharmacologist. Meyer is professor emeritus of pharmacology. He obtained his M.D. at the University of Zurich in 1967 and worked as assistant professor in clinical pharmacology at the University of California, San Francisco. In 1974, he became Head of Clinical Pharmacology at the University Hospital of Zurich. From 1983 to 2008, Meyer carried out research and taught as professor of pharmacology at