Ciaccio's glands Ciaccio's glands Ciaccio's glands or Wolfring's glands are small tubular accessory lacrimal glands ("glandulae lacrimales accessoriae") found in the lacrimal caruncle of the eyelid. They are located in the upper border of the tarsus, approximately in the middle between the extremities of the tarsal glands. Sometimes they are situated slightly above the tarsus. There are usually 2 to 5 of these glands in the upper eyelid, and their function is to produce tears which are secreted onto the surface of the conjunctiva. They are named after Italian anatomist Giuseppe Vincenzo Ciaccio (1824–1901), who described these glands in 1874. They are
Isotretinoin in young people who are still growing. Premature epiphyseal closure can occur in people with acne receiving recommended doses of Accutane. Isotretinoin is known to cause meibomian gland dysfunction which causes persistent keratoconjunctivitis sicca (dry eye). Problems with the meibomian and salivary glands are likely due to the non-selective apoptosis of the cells of the exocrine glands. Decreased night vision has been reported to persist in some people after discontinuation of isotretinoin therapy. The most common side effects are mucocutaneous: dry lips, skin and nose. Other common mucocutaneous side effects are inflammation and chapping of the lips (cheilitis), redness of