Pleiotropy correlations and responses to selection most often exemplify pleiotropy. Pleiotropic traits had been previously recognized in the scientific community but had not been experimented on until Gregor Mendel's 1866 pea plant experiment. Mendel recognized that certain pea plant traits (seed coat color, flower color, and axial spots) seemed to be inherited together; however, their correlation to a single gene has never been proven. The term "pleiotropie" was first coined by Ludwig Plate in his Festschrift, which was published in 1910. He originally defined pleiotropy as occurring when "several characteristics are dependent upon ... [inheritance]; these characteristics will then always appear
Journal of Heredity Journal of Heredity The Journal of Heredity is a peer-reviewed scientific journal concerned with heredity in a biological sense, covering all aspects of genetics. It is published by Oxford University Press on behalf of the American Genetic Association. The trends in topics that have been published in the journal reflect the history of the discipline of genetics. Early issues included many papers on eugenics, particularly under the editorial leadership of the journal's first two editors-in-chief, Paul Popenoe and R. C. Cook. Emphasis on eugenics in the journal declined throughout the 1940s and 1950s as support for the topic waned in