Alcoholic drink jugs suggest that intentionally fermented drinks existed at least as early as the Neolithic period (cir. 10,000 BC). Many animals also consume alcohol when given the opportunity and are affected in much the same way as humans, although humans are the only species known to produce alcoholic drinks intentionally. Beer is a beverage fermented from grain mash. It is typically made from barley or a blend of several grains and flavored with hops. Most beer is naturally carbonated as part of the fermentation process. If the fermented mash is distilled, then the drink becomes a spirit. In the Andean region,
Caffeinated alcoholic drink inferred that caffeinated alcoholic drinks cause one to act in ways that would be less likely if one were drinking non-caffeinated alcoholic drinks. The adverse effects of caffeinated alcoholic drinks have led to increased regulation. Under the Federal Food, Drug, and Cosmetic Act, a substance intentionally added to food (such as caffeine in alcoholic drinks) is deemed "unsafe" and is unlawful unless its particular use has been approved by FDA (Food and Drug Administration) regulation. The substance is subject to a prior sanction until the substance is Generally Regarded As Safe (GRAS). In order for a substance to be characterized