The Unselfish Gene of the novel is a nod to Richard Dawkins' 1976 book, "The Selfish Gene". Among the concepts developed in Dawkins' book is a theory of how natural selection may favor self-sacrifice and other forms of altruism. The themes of altruism and small gene sets play an important role in plot and character development in The Unselfish Gene. The Unselfish Gene is what might be termed "semi-hard" science fiction. The technology described in the book is well within the limits of early 21st century technology. Some of it, such as "The Anita", an atomic-bomb powered heavy lifter space ship, was actually
The Selfish Gene own valuable contributions to the field, the book has also stimulated research on human inclusive fitness. In the foreword to the book's 30th-anniversary edition, Dawkins said he "can readily see that [the book's title] might give an inadequate impression of its contents" and in retrospect thinks he should have taken Tom Maschler's advice and called the book "The Immortal Gene". In July 2017, "The Selfish Gene" was listed as the most influential science book of all time in a poll to celebrate the 30th anniversary of the Royal Society science book prize. Dawkins builds upon George C. Williams's book "Adaptation