Copying pencil Copying pencil A copying pencil, also indelible pencil or chemical pencil, is pencil whose lead contains a dye. The lead is fabricated by adding a dry water-soluble permanent dye to powdered graphite—used in standard graphite pencils—before binding the mixture with clay. Copying pencils were introduced in the 1870s and were originally marketed for copying documents, especially for making permanent copies of a permanent original. This was achieved by creating a hand-written document using a copying pencil, laying a moist tissue paper over the document and pressing down with a mechanical press. The water-soluble dye in the writing would be transferred
Lead poisoning affected by lead toxicity to varying degrees depending on species. Animals experience many of the same effects of lead exposure as humans do, such as abdominal pain, peripheral neuropathy, and behavioral changes such as increased aggression. Much of what is known about human lead toxicity and its effects is derived from animal studies. Animals are used to test the effects of treatments, such as chelating agents, and to provide information on the pathophysiology of lead, such as how it is absorbed and distributed in the body. Farm animals such as cows and horses as well as pet animals are also