Catgut suture treatment produces roughly twice the stitch-holding time of plain catgut, but greater tissue inflammation occurs. Full tensile strength is extended to 18–21 days. It is brown rather than straw-colored, and has improved smoothness due to the dry presentation of the thread (plain catgut is wet). It is otherwise similar to plain catgut. Fast catgut suture is heat-treated to give even more rapid absorption in the body. The first known absorbable sutures were made of the intestines of sheep. The manufacturing process was similar to that of natural musical strings for violins and guitar, and also of natural strings for tennis
Catgut Before 1900, the best strings for musical instruments were reputedly from Italy. Musicians believed the best were from Naples, though Rome and other Italian cities also produced excellent strings. Today high quality gut strings are produced mostly in Italy, Germany, and the United States. They are also made elsewhere, for example in India and Morocco, for local use. Catgut suture was once a widely used material in surgical settings. There is debate about whether to continue using catgut in a medical setting, since cotton is usually cheaper and wounds closed with either cotton or synthetic threads are less prone to