Issaouane Erg confined to basins. Sand in the Issaouane Erg, below the level of the sand dunes, has accumulated to a depth of 20 to 30 meters. It has barchan dunes as well as star dunes of 300 to 430 meters high. The presence of both barchan dunes (which form due to unidirectional winds) and star dunes (which form when winds from various directions deposit sand) "suggests that wind regimes have changed over time". NASA's "Earth Observatory" notes all three types of erg dunes are present in the photos of the Issaouane Erg taken from the International Space Station: stationary mega dunes,
ERG (gene) TLS/FUS in Ewing's sarcoma and acute myeloid leukemias respectively and function as transcriptional activators. ERG and its fusion proteins EWS-ERG and TLS/FUS-ERG inhibit apoptosis. "ERG" can fuse with TMPRSS2 protein to form an oncogenic fusion gene that is commonly found in human prostate cancer, especially in hormone-refractory prostate cancer. This suggests that "ERG" overexpression may contribute to development of androgen-independence in prostate cancer through disruption of androgen receptor signaling. The fusion gene is critical to the progression of cancer because it inhibits the androgen receptor expression and it binds and inhibits androgen receptors already present in the cell. Essentially TMPRSS2-ERG