Galena, Illinois for mayor and aldermen on May 24, 1841, replacing the board of trustees; Charles S. Hempstead was elected the first mayor with 185 of the 356 votes cast. The first census was also held that year, finding 1,900 inhabitants. By 1845 Galena was producing nearly 27,000 tons of lead ore and Jo Daviess County was producing 80 percent of the lead in the United States. Once one of the most important cities in the state, Galena was a hub on the Mississippi River between St. Louis and St. Paul. Due to erosion, the Galena River is now inaccessible to steamboats.
Galena, Alaska in the few last remaining dry parts of town. The flood dike the Air Force built around the runway managed to keep the river from inundating the runway and GILA. Efforts are currently underway to help Galena rebuild, with the assistance of the Federal Emergency Management Agency and volunteer groups. Galena is located at (64.740643, -156.885462). Galena is located on the north bank of the Yukon River, east of Nulato. The Innoko National Wildlife Refuge is southwest of Galena. According to the United States Census Bureau, the city has a total area of , of which, of it is land