Issaouane Erg with foreign assistance, including from Korea and Spain (Repsol signed an agreement to invest and explore in 1990). The oilfield has been in production since late 1998. Issaouane Erg The Issaouane Erg (also called Issaouane-N-Irrararene) is an approximately 38,000 km erg (sand sea) in Algeria's portion of the Sahara desert, located at . The Issaouane Erg is located near the Ahaggar Mountains. It is part of a major dune field that extends from Issaouane Erg in the north to the Sudanese Erg in the south, flanked by the Libyan erg of Murzuq. In the north, the Issaouane Erg ends at
ERG (gene) TLS/FUS in Ewing's sarcoma and acute myeloid leukemias respectively and function as transcriptional activators. ERG and its fusion proteins EWS-ERG and TLS/FUS-ERG inhibit apoptosis. "ERG" can fuse with TMPRSS2 protein to form an oncogenic fusion gene that is commonly found in human prostate cancer, especially in hormone-refractory prostate cancer. This suggests that "ERG" overexpression may contribute to development of androgen-independence in prostate cancer through disruption of androgen receptor signaling. The fusion gene is critical to the progression of cancer because it inhibits the androgen receptor expression and it binds and inhibits androgen receptors already present in the cell. Essentially TMPRSS2-ERG