Polyculture chemicals into the environment such as eutrophication of fresh water or the presence of excess atmospheric nitrogen are greatly reduced in polycultures. Other negative impacts of modern agriculture are similarly reduced. Excessive tillage occurs in most modern agricultural practices, but removes essential microbes and nutrients from the soil that are conserved in polycultures, especially permacultures. Agricultural machinery not only uses fossil fuels and creates waste, but is more costly to farmers. Because polyculture relies on natural systems of crop maintenance these costs can be eliminated as well. Modern agriculture is also dependent on a very limited number of plant species.
Plant defense against herbivory change their defenses in response to changes in nutrients. For example, if plants are grown in low-nitrogen conditions, then these plants will implement a defensive strategy composed of constitutive carbon-based defenses. If nutrient levels subsequently increase, by for example the addition of fertilizers, these carbon-based defenses will decrease. The growth rate hypothesis, also known as the "resource availability hypothesis", states that defense strategies are determined by the inherent growth rate of the plant, which is in turn determined by the resources available to the plant. A major assumption is that available resources are the limiting factor in determining the maximum