George C. Williams (biologist) should only be used where it is really necessary", and, that, when it is necessary, selection among genes or individuals would in general be the preferable explanation for it. He elaborated this view in later books and papers, which contributed to the development of a gene-centered view of evolution; Richard Dawkins built on Williams' ideas in this area in the book "The Selfish Gene". Williams was also well known for his work on the evolution of sex, and was an advocate of evolutionary medicine. In later books, including "Natural Selection: Domains, Levels and Challenges", Williams softened his views on group
On the Tendency of Species to form Varieties; and on the Perpetuation of Varieties and Species by Natural Means of Selection Letter" from Darwin to Asa Gray. This was the first announcement of the Darwin – Wallace theory of evolution by natural selection; the papers appeared in print on 20 August 1858. The presentation of the papers spurred Darwin to write a condensed "abstract" of his "big book" on "Natural Selection". This was published in November 1859 as "On the Origin of Species". On the voyage of the "Beagle" the young Charles Darwin took a break between graduating and starting his career as a clergyman to study the natural history of South America, an interest he had developed at the University