Galena cubic unit cell much like the mineral halite of the halide mineral group. Zinc, cadmium, iron, copper, antimony, arsenic, bismuth and selenium also occur in variable amounts in galena. Selenium substitutes for sulfur in the structure constituting a solid solution series. The lead telluride mineral altaite has the same crystal structure as galena. Within the weathering or oxidation zone galena alters to anglesite (lead sulfate) or cerussite (lead carbonate). Galena exposed to acid mine drainage can be oxidized to anglesite by naturally occurring bacteria and archaea, in a process similar to bioleaching. One of the oldest uses of galena was
Broken Hill ore deposit hornblende schists. The ore consists of massive, recrystallised sphalerite-rich, galena-sphalerite and galena-rich sulfide lenses in folded horizons, known as No. 2 Lens Formation and No.3 Lens Formation. Both have distinctive metal ratios and gangue minerals. The ore boundaries are parallel to the bedding planes. According to Gustafson, "There is evidence that the ore has been introduced into an old, already folded, rock and has replaced certain favourable layers of that rock, particle by particle, with large tonnages of garnet, rhodonite, fluorite, marmatite (and wurtzite), galena, and other minerals that constitute the orebodies." The Potosi-Footwall Gneiss is found on both sides