Mefloquine during the study. Mefloquine was the first Public-Private Venture (PPV) between the US Department of Defense and a pharmaceutical company. WRAIR transferred all its phase I and phase II clinical trial data to Hoffman LaRoche and Smith Kline. FDA approval as a treatment for malaria was swift. Most notably, phase III safety and tolerability trials were skipped. The drug was first approved and sold on a commercial basis in Switzerland in 1985. However, mefloquine was not approved by the FDA for prophylactic use until 1989. This approval was based primarily on compliance, while safety and tolerability were overlooked. Because of
People for the Ethical Treatment of Animals which it seeks to improve the treatment of, and also advocates for improvements for companion animals. In 2016, PETA Asia-Pacific shocked customers with a fake pop-up shop in Bangkok called The Leather Work, which seemed to specialize in "luxury" leather bags, shoes, and other clothing and accessories. Inside the items, though, were what appeared to be the gory flesh, sinews, beating hearts, and blood of animals slaughtered for such items. According to the "Asian Correspondent", the stunt caused shoppers to jump back and gasp in horror. PETA claims "to have found workers in crocodile farms 'sawing open reptile's necks while