Half sphere exposure Half sphere exposure Half Sphere Exposure (HSE) is a protein solvent exposure measure that was first introduced by . Like all solvent exposure measures it measures how buried amino acid residues are in a protein. It is found by counting the number of amino acid neighbors within two half spheres of chosen radius around the amino acid. The calculation of HSE is found by dividing a contact number (CN) sphere in two halves by the plane perpendicular to the Cβ-Cα vector. This simple division of the CN sphere results in two strikingly different measures, HSE-up and HSE-down. HSE-up is defined
What Is This Thing Called Love? (short story) other, and wind up engaging in reproductive activities after all. What Is This Thing Called Love? (short story) "What Is This Thing Called Love?" is a science fiction short story by Isaac Asimov. The story was requested by Cele Goldsmith Lalli, editor of "Amazing Stories", as a satire of an article in "Playboy" called "Girls of the Slime God" which had suggested that pulp science fiction stories were concerned with aliens and sex. The story appeared in the March 1961 issue of "Amazing" as "Playboy and the Slime God", but Asimov later retitled it "What Is This Thing Called Love?"