Half sphere exposure Half sphere exposure Half Sphere Exposure (HSE) is a protein solvent exposure measure that was first introduced by . Like all solvent exposure measures it measures how buried amino acid residues are in a protein. It is found by counting the number of amino acid neighbors within two half spheres of chosen radius around the amino acid. The calculation of HSE is found by dividing a contact number (CN) sphere in two halves by the plane perpendicular to the Cβ-Cα vector. This simple division of the CN sphere results in two strikingly different measures, HSE-up and HSE-down. HSE-up is defined
Sphere (2013 film) Sphere (2013 film) Sphere is a British animated short film created in 2013 by Aardman Animations for the University of Bristol and the Elizabeth Blackwell Institute. It was directed by Richard Webber. "Sphere " "involved asking members of the general public for their views on the technologies being developed in a project called SPHERE (Sensor Platform for HEalthcare in a Residential Environment), and what the outcomes might mean for them". As a result, "The creatures within the animation voiced opinions which reflected public reaction to SPHERE". "Sphere " was created in preparation for the launch of the Elizabeth Blackwell Institute.