Half sphere exposure Half sphere exposure Half Sphere Exposure (HSE) is a protein solvent exposure measure that was first introduced by . Like all solvent exposure measures it measures how buried amino acid residues are in a protein. It is found by counting the number of amino acid neighbors within two half spheres of chosen radius around the amino acid. The calculation of HSE is found by dividing a contact number (CN) sphere in two halves by the plane perpendicular to the Cβ-Cα vector. This simple division of the CN sphere results in two strikingly different measures, HSE-up and HSE-down. HSE-up is defined
What Is a Man Without a Moustache? Times" had also expressed opinions of a divided nature. He called the film "pleasant if inconsequential", offered an opinion that it contains "good-natured sensibility" and a "slightly fabulous tone" while still feeling like "magic realism, without the magic", and concluded his review by stating that "the pleasant pointless of it all is laced with a tantalizing tease of allegory suggested by the dialectical twins and the strain of mellow nationalism in the dialogue." Reviewing the film for "TV Guide", Maitland McDonagh awarded the film three stars out of four calling it "sardonic" and "absurdist". What Is a Man Without a