Mefloquine one. Plasma concentrations of the (–)-enantiomer are significantly higher than those for the (+)-enantiomer, and the pharmacokinetics between the two enantiomers are significantly different. The (+)-enantiomer has a shorter half-life than the (–)-enantiomer. According to some research, the (+)-enantiomer is more effective in treating malaria, and the (–)-enantiomer specifically binds to adenosine receptors in the central nervous system, which may explain some of its psychotropic effects. Mefloquine was formulated at Walter Reed Army Institute of Research (WRAIR) in the 1970s shortly after the end of the Vietnam war. Mefloquine was number 142,490 of a total of 250,000 antimalarial compounds screened
People for the Ethical Treatment of Animals which it seeks to improve the treatment of, and also advocates for improvements for companion animals. In 2016, PETA Asia-Pacific shocked customers with a fake pop-up shop in Bangkok called The Leather Work, which seemed to specialize in "luxury" leather bags, shoes, and other clothing and accessories. Inside the items, though, were what appeared to be the gory flesh, sinews, beating hearts, and blood of animals slaughtered for such items. According to the "Asian Correspondent", the stunt caused shoppers to jump back and gasp in horror. PETA claims "to have found workers in crocodile farms 'sawing open reptile's necks while