Monsoon trough of the summertime Asian monsoon is in its normal orientation (oriented east-southeast to west-northwest), tropical cyclones along its periphery will move with a westward motion. If it reverses its orientation, orienting southwest to northeast, tropical cyclones will move more poleward. Tropical cyclone tracks with S-shapes tend to be associated with reverse-oriented monsoon troughs. The South Pacific convergence zone and South American convergence zones are generally reverse oriented. The failure of the monsoon trough, or the ITCZ, to move south of the equator in the eastern Pacific Ocean and Atlantic Ocean during the southern hemisphere summer, is considered one of the
Trough level metabolized or cleared by the body, so the concentration of drug that remains available is dropping. In a medicine that is administered periodically, the trough level should be measured just before the administration of the next dose in order to avoid overdosing. A trough level is contrasted with a "peak level", which is the highest level of the medicine in the body, and the "average level", which is the mean level over time. It helps in therapeutic drug monitoring. It is widely used in clinical trials for newer medicines for its therapeutic effectiveness and safety. Trough level In medicine and