Antimalarial medication multi-drug resistant "P. falciparum". It is a very potent blood schizonticide with a long half-life. It is thought to act by forming toxic heme complexes that damage parasitic food vacuoles. Mefloquine is effective in prophylaxis and for acute therapy. It is now used solely for the prevention of resistant strains of "P. falciparum" (usually combined with Artesunate) despite being effective against "P. vivax", "P. ovale" and "P. marlariae". Chloroquine/proguanil or sulfa drug-pyrimethamine combinations should be used in all other plasmodia infections. The major commercial manufacturer of mefloquine-based malaria treatment is Roche Pharmaceuticals, which markets the drug under the trade name
International Association for the Treatment of Sexual Offenders as those individuals who (1) access child pornography due to impulse without any specific sexual interest in children; (2) access child pornography to satisfy sexual fantasies but do not commit contact sex offenses; (3) make and handout child pornography just for financial gain and benefit; and (4) use the Internet to facilitate contact sex offenses. Sexual offenders create many challenges for treatment providers probation officers, and even just regular people in their community. Sexual offenders create challenges because the treatment providers and probation officers have to decide what care is best and what limitations are necessary for that specific individual