Half sphere exposure both HSEα and HSEβ based on a big dataset by using multiple-step iterative deep neural-network learning. The predicted HSEa shows a higher correlation coefficient to the stability change by residue mutants than predicted HSEβ and ASA. The results, together with its easy Ca-atom-based calculation, highlight the potential usefulness of predicted HSEa for protein structure prediction and refinement as well as function prediction. Half sphere exposure Half Sphere Exposure (HSE) is a protein solvent exposure measure that was first introduced by . Like all solvent exposure measures it measures how buried amino acid residues are in a protein. It is found
Sphere (novel) team returns to the habitat, Adams succeeds in opening and entering the sphere. Meanwhile, on the surface, a Pacific cyclone forces the supporting Naval ships to evacuate, trapping and isolating the scientists on the ocean floor for five days. Adams is found and returned to the DH-8 Habitat where he awakens with a terrible headache and little-to-no memory of how he opened the sphere or what occurred while he was inside. Immediately afterwards, the team is contacted by an intelligent, seemingly friendly alien entity that calls itself "Jerry". At first, Jerry communicates with the scientists using a numeric code transmitted