Catechol one of the main natural phenols in argan oil and is a component of castoreum, a substance from the castor gland of beavers, used in perfumery. It is also found in "Agaricus bisporus". Catechol moieties are also found widely within the natural world. Arthropod cuticle consists of chitin linked by a catechol moiety to protein. The cuticle may be strengthened by cross-linking (tanning and sclerotization), in particular, in insects, and of course by biomineralization. Catechols such as DHSA are produced through the metabolism of cholesterol by bacteria such as "Mycobacterium tuberculosis". Urushiols are naturally existing organic compounds that have the
Regulation of food and dietary supplements by the U.S. Food and Drug Administration concerns about the safety of new food additives. The amendment established the designation of "generally recognized as safe", which refers to chemicals or substances which can be used as food additives without further evaluation or testing just because they have been long used and there is broad acceptance of their use. New food additives would be subject to testing including by the "Delaney clause". The Delaney clause was a provision in the amendment which said that if a substance were found to cause cancer in man or animal, then it could not be used as a food additive. The Dietary