Half sphere exposure used in predicting discontinuous B-cell epitopes. Song et al. have developed an online webserver termed HSEpred to predict half-sphere exposure from protein primary sequences. HSEpred server can achieve the correlation coefficients of 0.72 and 0.68 between the predicted and observed HSE-up and HSE-down measures, respectively, when evaluated on a well-prepared non-homologous protein structure dataset. Moreover, residue contact number (CN) can also be accurately predicted by HSEpred webserver using the summation of the predicted HSE-up and HSE-down values, which has further enlarged the application of this new solvent exposure measure. Recently, Heffernan et al. has developed the most accurate predictor for
Science On a Sphere have conducted their own evaluation reports as well to better understand the educational impacts of Science On a Sphere. Science On a Sphere is installed in science museums, zoos and aquariums, and visitors centers around the world. New sites are continually being added: In 2005, the NASA Goddard Space Flight Center ordered what would become the eighth SOS to be permanently installed. Michael Starobin, Goddard's senior media producer at the time, began the process of developing a presentation that would showcase NASA data. Through the autumn of 2005 and into the winter of 2006, Starobin worked on collecting source material