Mefloquine one. Plasma concentrations of the (–)-enantiomer are significantly higher than those for the (+)-enantiomer, and the pharmacokinetics between the two enantiomers are significantly different. The (+)-enantiomer has a shorter half-life than the (–)-enantiomer. According to some research, the (+)-enantiomer is more effective in treating malaria, and the (–)-enantiomer specifically binds to adenosine receptors in the central nervous system, which may explain some of its psychotropic effects. Mefloquine was formulated at Walter Reed Army Institute of Research (WRAIR) in the 1970s shortly after the end of the Vietnam war. Mefloquine was number 142,490 of a total of 250,000 antimalarial compounds screened
What is this Feeling? and new?/I felt the moment I laid eyes on you/My pulse is rushing/My head is reeling/My face is flushing/What is this feeling?/Fervid as a flame/Does it have a name?"). The irony comes in when phrases traditionally used for love songs are revealed to be expressing hate. When Galinda and Elphaba describe each other, Galinda complains about Elphaba being "utterly impossible to describe", while Elphaba simply calls Galinda "blonde". At the end of the song, Elphaba scares Galinda, by saying "Boo", with Galinda letting out a high-pitched squeal. What is this Feeling? "What is this Feeling?" is a song from the