Mefloquine one. Plasma concentrations of the (–)-enantiomer are significantly higher than those for the (+)-enantiomer, and the pharmacokinetics between the two enantiomers are significantly different. The (+)-enantiomer has a shorter half-life than the (–)-enantiomer. According to some research, the (+)-enantiomer is more effective in treating malaria, and the (–)-enantiomer specifically binds to adenosine receptors in the central nervous system, which may explain some of its psychotropic effects. Mefloquine was formulated at Walter Reed Army Institute of Research (WRAIR) in the 1970s shortly after the end of the Vietnam war. Mefloquine was number 142,490 of a total of 250,000 antimalarial compounds screened
What Is Love and produced by German music producer and composer Dee Dee Halligan (Dieter Lünstedt a.k.a. Tony Hendrik) and Junior Torello (Karin Hartmann-Eisenblätter a.k.a. Karin van Haaren) of Coconut Records in Cologne. They were waiting for the right singer for the song. Trinidadian-born singer Nestor Alexander Haddaway was then chosen to sing it. He used to work as a producer, dancer and choreographer before he was signed to Coconut Records. In a 2012 interview Haddaway said about the making of "What Is Love": "What Is Love" was released in Europe in May 1993 and in the US in August 1993. It peaked