Half sphere exposure used in predicting discontinuous B-cell epitopes. Song et al. have developed an online webserver termed HSEpred to predict half-sphere exposure from protein primary sequences. HSEpred server can achieve the correlation coefficients of 0.72 and 0.68 between the predicted and observed HSE-up and HSE-down measures, respectively, when evaluated on a well-prepared non-homologous protein structure dataset. Moreover, residue contact number (CN) can also be accurately predicted by HSEpred webserver using the summation of the predicted HSE-up and HSE-down values, which has further enlarged the application of this new solvent exposure measure. Recently, Heffernan et al. has developed the most accurate predictor for
What Is a Man Without a Moustache? 62 based on five reviews from critics. In a review for "Variety" magazine, critic Deborah Young called "What Is a Man Without a Moustache?" "an entertaining romantic comedy" and a "good-humored film" while, on the other hand, noting that the film should be better received by local and regional audiences due to its story being "a hard sell abroad". Author and film critic Michael Atkinson, writing for "The Village Voice", expressed his divided opinion that the film "is not remarkable or ingenious" but that it still is "adept enough for a pass on." Critic Nathan Lee of "The New York