Half sphere exposure used in predicting discontinuous B-cell epitopes. Song et al. have developed an online webserver termed HSEpred to predict half-sphere exposure from protein primary sequences. HSEpred server can achieve the correlation coefficients of 0.72 and 0.68 between the predicted and observed HSE-up and HSE-down measures, respectively, when evaluated on a well-prepared non-homologous protein structure dataset. Moreover, residue contact number (CN) can also be accurately predicted by HSEpred webserver using the summation of the predicted HSE-up and HSE-down values, which has further enlarged the application of this new solvent exposure measure. Recently, Heffernan et al. has developed the most accurate predictor for
What Is This Thing Called Love? forms the basis of several jazz compositions (contrafact), such as "Hot House" by Tadd Dameron What Is This Thing Called Love? "What Is This Thing Called Love?" is a 1929 popular song written by Cole Porter, for the musical "Wake Up and Dream". It was first performed by Elsie Carlisle in March 1929. The song has become a popular jazz standard and one of Porter's most often played compositions. "Wake Up and Dream" ran for 263 shows in London. The show was also noticed in New York, and the critics praised Tilly Losch's performance of the song. The show was