Lycopene the structure of the molecule was determined by 1931. In its natural, all-"trans" form, the molecule is long and straight, constrained by its system of 11 conjugated double bonds. Each extension in this conjugated system reduces the energy required for electrons to transition to higher energy states, allowing the molecule to absorb visible light of progressively longer wavelengths. Lycopene absorbs all but the longest wavelengths of visible light, so it appears red. Plants and photosynthetic bacteria naturally produce all-"trans" lycopene. When exposed to light or heat, lycopene can undergo isomerization to any of a number of "cis"-isomers, which have a
Retinal pigment epithelium degeneration and retinitis pigmentosa. RPE are also involved in diabetic retinopathy. Gardner syndrome is characterized by FAP (Familial Adenomatous Polyps), osseous and soft tissue tumors, retinal pigment epithelium hypertrophy and impacted teeth. Retinal pigment epithelium The pigmented layer of retina or retinal pigment epithelium (RPE) is the pigmented cell layer just outside the neurosensory retina that nourishes retinal visual cells, and is firmly attached to the underlying choroid and overlying retinal visual cells. The RPE was known in the 18th and 19th centuries as the pigmentum nigrum, referring to the observation that the RPE is dark (black in many animals,