Half sphere exposure used in predicting discontinuous B-cell epitopes. Song et al. have developed an online webserver termed HSEpred to predict half-sphere exposure from protein primary sequences. HSEpred server can achieve the correlation coefficients of 0.72 and 0.68 between the predicted and observed HSE-up and HSE-down measures, respectively, when evaluated on a well-prepared non-homologous protein structure dataset. Moreover, residue contact number (CN) can also be accurately predicted by HSEpred webserver using the summation of the predicted HSE-up and HSE-down values, which has further enlarged the application of this new solvent exposure measure. Recently, Heffernan et al. has developed the most accurate predictor for
Mutha Is Half a Word Mutha Is Half a Word Mutha Is Half A Word is the debut album by American comic and actress LaWanda Page, released in 1971 on the Laff Records label. The comic, born in Ohio and raised in St. Louis, MO as Alberta Peal, used only the first name of her stage name for the duration of her recordings with Laff Records and for the duration of her career as a stand-up comedian, which began in the 1960s after careers as a strip dancer and vaudeville performer. Some of Page's most famous stand-up monologues are included in this album including "The