Half sphere exposure both HSEα and HSEβ based on a big dataset by using multiple-step iterative deep neural-network learning. The predicted HSEa shows a higher correlation coefficient to the stability change by residue mutants than predicted HSEβ and ASA. The results, together with its easy Ca-atom-based calculation, highlight the potential usefulness of predicted HSEa for protein structure prediction and refinement as well as function prediction. Half sphere exposure Half Sphere Exposure (HSE) is a protein solvent exposure measure that was first introduced by . Like all solvent exposure measures it measures how buried amino acid residues are in a protein. It is found
Public sphere and "what is not" discussed. Benhabib argues for feminists to counter the popular public discourse in their own counter public. The public sphere was long regarded as men's domain whereas women were supposed to inhabit the private domestic sphere. A distinct ideology that prescribed separate spheres for women and men emerged during the industrial revolution. The concept of heteronormativity is used to describe the way in which those who fall outside of the basic male/female dichotomy of gender or whose sexual orientations are other than heterosexual cannot meaningfully claim their identities, causing a disconnect between their public selves and their