Bruxism the phrase "wailing and gnashing of teeth" is used to describe the fate of sinners in hell (). In David Lynch's 1977 film "Eraserhead", Henry Spencer's partner ("Mary X") is shown tossing and turning in her sleep, and snapping her jaws together violently and noisily, depicting sleep bruxism. In Stephen King's 1988 novel "The Tommyknockers", the sister of central character Bobbi Anderson also had bruxism. In the 2000 film "Requiem for a Dream", the character of Sara Goldfarb (Ellen Burstyn) begins taking an amphetamine-based diet pill and develops bruxism. In the 2005 film "Beowulf & Grendel", a modern reworking of
Bruxism to evaluate in which situations bruxism is most prevalent. Many different medications have been used to treat bruxism, including benzodiazepines, anticonvulsants, beta blockers, dopamine agents, antidepressants, muscle relaxants, and others. However, there is little, if any, evidence for their respective and comparative efficacies with each other and when compared to a placebo. A multiyear systematic review to investigate the evidence for drug treatments in sleep bruxism published in 2014 ("Pharmacotherapy for Sleep Bruxism". Macedo, et al.) found "insufficient evidence on the effectiveness of pharmacotherapy for the treatment of sleep bruxism." Specific drugs that have been studied in sleep bruxism are