Esophageal pH monitoring developed a dependable external reference electrode. Using this technique to monitor esophageal acid exposure patients for periods up to 24 hours, DeMeester and Johnson were able to identify the most important parameters of esophageal acid exposure, and they developed a composite pH score to quantify gastroesophageal reflux. The initial 24-hour pH studies required hospitalization until the introduction of microcircuits in the 1980s that allowed portable esophageal pH monitoring in an outpatient setting. Gastroesophageal reflux disease (GERD) is a common disease in western countries. In the United States, 7% of the population experiences heartburn daily and 44% at least once a
Alkali hydroxide Alkali hydroxide The alkali hydroxides are a class of chemical compounds which are composed of an alkali metal cation and the hydroxide anion (OH). The alkali hydroxides are: The most common alkali hydroxide is sodium hydroxide, which is readily available in most hardware stores in products such as a drain cleaner. Another common alkali hydroxide is potassium hydroxide. This is available as a solution used for cleaning terraces and other areas made out of wood. All alkali hydroxides are very corrosive, being strongly alkaline. A typical school demonstration demonstrates what happens when a piece of an alkali metal is introduced