Antimalarial medication multi-drug resistant "P. falciparum". It is a very potent blood schizonticide with a long half-life. It is thought to act by forming toxic heme complexes that damage parasitic food vacuoles. Mefloquine is effective in prophylaxis and for acute therapy. It is now used solely for the prevention of resistant strains of "P. falciparum" (usually combined with Artesunate) despite being effective against "P. vivax", "P. ovale" and "P. marlariae". Chloroquine/proguanil or sulfa drug-pyrimethamine combinations should be used in all other plasmodia infections. The major commercial manufacturer of mefloquine-based malaria treatment is Roche Pharmaceuticals, which markets the drug under the trade name
People for the Ethical Treatment of Animals which it seeks to improve the treatment of, and also advocates for improvements for companion animals. In 2016, PETA Asia-Pacific shocked customers with a fake pop-up shop in Bangkok called The Leather Work, which seemed to specialize in "luxury" leather bags, shoes, and other clothing and accessories. Inside the items, though, were what appeared to be the gory flesh, sinews, beating hearts, and blood of animals slaughtered for such items. According to the "Asian Correspondent", the stunt caused shoppers to jump back and gasp in horror. PETA claims "to have found workers in crocodile farms 'sawing open reptile's necks while