Half sphere exposure Half sphere exposure Half Sphere Exposure (HSE) is a protein solvent exposure measure that was first introduced by . Like all solvent exposure measures it measures how buried amino acid residues are in a protein. It is found by counting the number of amino acid neighbors within two half spheres of chosen radius around the amino acid. The calculation of HSE is found by dividing a contact number (CN) sphere in two halves by the plane perpendicular to the Cβ-Cα vector. This simple division of the CN sphere results in two strikingly different measures, HSE-up and HSE-down. HSE-up is defined
Bloch sphere sphere is also known as the Poincaré sphere and specifically represents different types of polarizations. Six common polarization types exist and are called Jones Vectors. Indeed Henri Poincaré was the first to suggest the use of this kind of geometrical representation at the end of 19th century, as a three-dimensional representation of Stokes parameters. The natural metric on the Bloch sphere is the Fubini–Study metric. The mapping from the unit 3-sphere in the two-dimensional state space ℂ to the Bloch sphere is the Hopf fibration. Given an orthonormal basis, any pure state formula_3 of a two-level quantum system can be