Half sphere exposure Half sphere exposure Half Sphere Exposure (HSE) is a protein solvent exposure measure that was first introduced by . Like all solvent exposure measures it measures how buried amino acid residues are in a protein. It is found by counting the number of amino acid neighbors within two half spheres of chosen radius around the amino acid. The calculation of HSE is found by dividing a contact number (CN) sphere in two halves by the plane perpendicular to the Cβ-Cα vector. This simple division of the CN sphere results in two strikingly different measures, HSE-up and HSE-down. HSE-up is defined
Half a Life (memoir) could in no way have avoided the accident, the book details his attempts, over half his life, to come to terms with his feelings of responsibility. "Half a Life" was enthusiastically received by critics here and abroad. Writing in "The Guardian", writer and critic Robert McCrum called the book "a masterpiece...'Half my life ago, I killed a girl'. You'll rarely get a better first line. What follows—Strauss's precise, honest and rigorous account of a fateful road accident and its harrowing aftermath—fulfills every hope aroused in the casual reader. What starts as an 18-year-old's carefree outing in his father's car leads