Antimalarial medication "Lariam". Lariam is fairly expensive at around 3 € per tablet (pricing of the year 2000). A dose of 15–25 mg/kg is recommended, depending on the prevalence of mefloquine resistance. The increased dosage is associated with a much greater level of intolerance, most noticeably in young children; with the drug inducing vomiting and esophagitis. It was not recommended for use during the first trimester, although considered safe during the second and third trimesters; nevertheless, in October 2011, the Centers for Disease Control and Prevention (CDC) changed its recommendation and approved use of Mefloquine for both prophylaxis and treatment of malaria
International Association for the Treatment of Sexual Offenders the context of their family, school, and other social systems in order to fully understand and decide the treatment and care for the juvenile. Another important element to keep in mind when choosing a treatment is to base it on a developmental perspective, which means it is sensitive to developmental change. This is necessary because during adolescence the brain is not fully developmental and is subjected to change. During assessment and treatment focus not only on the risks of the youths but also their strengths. Keep in mind that sexual interests of youth do change over adolescence and sexual orientation