Mefloquine drug composed of only the (+)-enantiomer. Mefloquine alters cholinergic synaptic transmission through both postsynaptic and presynaptic actions. The postsynaptic action to inhibit acetylcholinesterase changes transmission across synapses in the brain. Mefloquine Mefloquine, sold under the brand names Lariam among others, is a medication used to prevent or treat malaria. When used for prevention it is taken once a week and should be started one or two weeks before potential exposure and continued for four weeks after potential exposure. It can be used to treat mild or moderate malaria but should not be used to treat severe malaria. It is taken
Things Ain't What They Used to Be Be", "Blue Serge" and "Moon Mist". Jazz musician and historian Chris Tyle argues that most likely Mercer Ellington came up with the melody and his father then arranged the song for the band. The song is most often played as an instrumental. Lyrics were written by Ted Persons. Johnny Hodges played it first, in Hollywood on July 3, 1941. Duke Ellington played it for the film "Cabin in the Sky" (1943). Things Ain't What They Used to Be "Things Ain't What They Used to Be" is a 1942 jazz standard with music by Mercer Ellington and lyrics by Ted Persons.