Half sphere exposure used in predicting discontinuous B-cell epitopes. Song et al. have developed an online webserver termed HSEpred to predict half-sphere exposure from protein primary sequences. HSEpred server can achieve the correlation coefficients of 0.72 and 0.68 between the predicted and observed HSE-up and HSE-down measures, respectively, when evaluated on a well-prepared non-homologous protein structure dataset. Moreover, residue contact number (CN) can also be accurately predicted by HSEpred webserver using the summation of the predicted HSE-up and HSE-down values, which has further enlarged the application of this new solvent exposure measure. Recently, Heffernan et al. has developed the most accurate predictor for
Mutha Is Half a Word Blind Woman" and "Smell the Sardines", bits she performed on TV later in her career. She also parodies the hit "Winchester Cathedral" in which she explains that a man working at a funeral parlor discovered a cork in a man's butt, taking the cork out only to hear the butt singing the song. The title of the book "Mutha Is Half a Word: Intersections of Folklore, Vernacular, Myth, and Queerness in Black Female Culture (Black Performance and Cultural Criticism)" is a reference to this album as it stands as a stereotype of modern black female humor. Mutha Is Half a