Half sphere exposure both HSEα and HSEβ based on a big dataset by using multiple-step iterative deep neural-network learning. The predicted HSEa shows a higher correlation coefficient to the stability change by residue mutants than predicted HSEβ and ASA. The results, together with its easy Ca-atom-based calculation, highlight the potential usefulness of predicted HSEa for protein structure prediction and refinement as well as function prediction. Half sphere exposure Half Sphere Exposure (HSE) is a protein solvent exposure measure that was first introduced by . Like all solvent exposure measures it measures how buried amino acid residues are in a protein. It is found
Dyson sphere Dyson sphere A Dyson sphere is a hypothetical megastructure that completely encompasses a star and captures a large percentage of its power output. The concept is a thought experiment that attempts to explain how a spacefaring civilization would meet its energy requirements once those requirements exceed what can be generated from the home planet's resources alone. Only a fraction of a star's energy emissions reach the surface of any orbiting planet. Building structures encircling a star would enable a civilization to harvest far more energy. The first contemporary description of the structure was by Olaf Stapledon in his science fiction