Mefloquine during the study. Mefloquine was the first Public-Private Venture (PPV) between the US Department of Defense and a pharmaceutical company. WRAIR transferred all its phase I and phase II clinical trial data to Hoffman LaRoche and Smith Kline. FDA approval as a treatment for malaria was swift. Most notably, phase III safety and tolerability trials were skipped. The drug was first approved and sold on a commercial basis in Switzerland in 1985. However, mefloquine was not approved by the FDA for prophylactic use until 1989. This approval was based primarily on compliance, while safety and tolerability were overlooked. Because of
People for the Ethical Treatment of Animals used for live transport and traditional religious slaughter. The organization has also used the PETA Lettuce Ladies in local demonstrations. PETA Asia-Pacific regularly demonstrates against KFC outlets to promote better treatment of chickens used by the company. PETA Asia-Pacific supports the PETA campaign "I'd Rather Go Naked Than Wear Fur," in which celebrities appear nude to express their opposition to wearing fur. The group also stages anti-fur events to publicize its opposition to fur. PETA Asia-Pacific has been involved in several undercover investigations of fur farms in China. The group regularly protests the use of animals in entertainment, including circuses.