Mefloquine during the study. Mefloquine was the first Public-Private Venture (PPV) between the US Department of Defense and a pharmaceutical company. WRAIR transferred all its phase I and phase II clinical trial data to Hoffman LaRoche and Smith Kline. FDA approval as a treatment for malaria was swift. Most notably, phase III safety and tolerability trials were skipped. The drug was first approved and sold on a commercial basis in Switzerland in 1985. However, mefloquine was not approved by the FDA for prophylactic use until 1989. This approval was based primarily on compliance, while safety and tolerability were overlooked. Because of
Community Alliance for the Ethical Treatment of Youth Community Alliance for the Ethical Treatment of Youth The Community Alliance For the Ethical Treatment of Youth (CAFETY) is an advocacy group for people enrolled in residential treatment programs for at-risk teenagers. The group's mission includes advocating for access to advocates, due process, alternatives to aversive behavioral interventions, and alternatives to restraints and seclusion for young people in treatment programs. They have also called for the routine reporting of abuse in residential treatment programs, as well as federal government oversight and regulation of residential treatment programs. CAFETY is registered as a nonprofit corporation in New York. It is governed by