Mefloquine developing world is about US$0.6–1.3 per dose. In the United States it costs about $10 a dose. Mefloquine is used to both prevent and treat certain forms of malaria. Mefloquine is useful for the prevention of malaria in all areas except for those where parasites may have resistance to multiple medications, and is one of several anti-malarial medications recommended by the United States Centers for Disease Control and Prevention for this purpose. It is also recommended by the Infectious Disease Society of America for malaria prophylaxis as a first or second-line agent, depending on resistance patterns in the malaria found
Alternative treatments used for the common cold children by 18%. Vitamin C also decreased the severity of colds. A systematic review by the Cochrane Collaboration, last updated in 2014, examines twenty-four randomized controlled trials studying various echinacea preparations for prevention and treatment of the common cold. Echinacea showed no benefit over placebo for prevention. Evidence for treatment was inconsistent. Reported side effects were rare. 2007 meta-analyses conclude that there is some evidence that echinacea may reduce either the duration or severity of the common cold, but results are not consistent. Use of echinacea preparations is not currently recommended. In the twelfth century, Moses Maimonides wrote, "Chicken soup