Mefloquine one. Plasma concentrations of the (–)-enantiomer are significantly higher than those for the (+)-enantiomer, and the pharmacokinetics between the two enantiomers are significantly different. The (+)-enantiomer has a shorter half-life than the (–)-enantiomer. According to some research, the (+)-enantiomer is more effective in treating malaria, and the (–)-enantiomer specifically binds to adenosine receptors in the central nervous system, which may explain some of its psychotropic effects. Mefloquine was formulated at Walter Reed Army Institute of Research (WRAIR) in the 1970s shortly after the end of the Vietnam war. Mefloquine was number 142,490 of a total of 250,000 antimalarial compounds screened
This Is What You Came For This Is What You Came For "This Is What You Came For" is a song by Scottish DJ and record producer Calvin Harris, featuring Barbadian singer Rihanna. It was released on 29 April 2016, through Columbia Records and Westbury Road. The song was written by Taylor Swift, who was initially credited with the pseudonym Nils Sjöberg. Rihanna and Harris had previously collaborated on her sixth studio album, "Talk That Talk", which included the international chart-topper "We Found Love" and US top five single "Where Have You Been", the former of which was written and produced by Harris. He played the