Chloroquine malaria from "Plasmodium vivax", "P. ovale", and "P. malariae", excluding the malaria parasite "Plasmodium falciparum", for it started to develop widespread resistance to it. Chloroquine has been extensively used in mass drug administrations, which may have contributed to the emergence and spread of resistance. It is recommended to check if chloroquine is still effective in the region prior to using it. In areas where resistance is present, other antimalarials, such as mefloquine or atovaquone, may be used instead. The Centers for Disease Control and Prevention recommend against treatment of malaria with chloroquine alone due to more effective combinations. In treatment
The purpose of a system is what it does be balanced by a more straightforwardly descriptive view. The term is used in many fields including biology and management. The purpose of a system is what it does The purpose of a system is what it does (POSIWID) is a systems thinking heuristic coined by Stafford Beer. Stafford Beer coined the term POSIWID and used it many times in public addresses. In his address to the University of Valladolid, Spain, in October 2001, he said "According to the cybernetician, the purpose of a system is what it does. This is a basic dictum. It stands for bald fact, which makes