Acetophenone is also a component of castoreum, the exudate from the castor sacs of the mature beaver. In the late 19th and early 20th centuries, acetophenone was used in medicine. It was marketed as a hypnotic and anticonvulsant under brand name Hypnone. The typical dosage was 0.12 to 0.3 milliliters. It was considered to have superior sedative effects to both paraldehyde and chloral hydrate. In humans, acetophenone is metabolized to benzoic acid, carbonic acid, and acetone. Hippuric acid occurs as an indirect metabolite and its quantity in urine may be used to confirm acetophenone exposure, although other substances, like toluene, also
Substance intoxication code) include: The term contact high is sometimes used to describe intoxication without direct administration, either by second-hand smoke (as with cannabis), or by placebo in the presence of others who are intoxicated. Substance intoxication Substance intoxication is a type of substance use disorder which is potentially maladaptive and impairing, but reversible, and associated with recent use of a substance. If the symptoms are severe, the term "substance intoxication delirium" may be used. Slang terms include: getting high (generic) or being stoned or blazed (usually in reference to cannabis), with many more specific slang terms for each particular type of