Malaria in pregnant women and infants, and in preschool children where transmission is seasonal. There are a number of medications that can help prevent or interrupt malaria in travelers to places where infection is common. Many of these medications are also used in treatment. In places where "Plasmodium" is resistant to one or more medications, three medications—mefloquine, doxycycline , or the combination of atovaquone/proguanil ("Malarone")—are frequently used for prevention. Doxycycline and the atovaquone/proguanil are better tolerated while mefloquine is taken once a week. Areas of the world with chloroquine sensitive malaria are uncommon. The protective effect does not begin immediately, and
Alternative treatments used for the common cold children by 18%. Vitamin C also decreased the severity of colds. A systematic review by the Cochrane Collaboration, last updated in 2014, examines twenty-four randomized controlled trials studying various echinacea preparations for prevention and treatment of the common cold. Echinacea showed no benefit over placebo for prevention. Evidence for treatment was inconsistent. Reported side effects were rare. 2007 meta-analyses conclude that there is some evidence that echinacea may reduce either the duration or severity of the common cold, but results are not consistent. Use of echinacea preparations is not currently recommended. In the twelfth century, Moses Maimonides wrote, "Chicken soup