Bruxism unaccompanied by mandibular movements."A movement disorder of the masticatory system characterized by teeth-grinding and clenching during sleep as well as wakefulness." "Non-functional contact of the mandibular and maxillary teeth resulting in clenching or tooth grinding due to repetitive, unconscious contraction of the masseter and temporalis muscles." "Parafunctional grinding of teeth or an oral habit consisting of involuntary rhythmic or spasmodic non-functional gnashing, grinding or clenching of teeth in other than chewing movements of the mandible which may lead to occlusal trauma." "Periodic repetitive clenching or rhythmic forceful grinding of the teeth." Bruxism can be subdivided into two types based upon
Bruxism to evaluate in which situations bruxism is most prevalent. Many different medications have been used to treat bruxism, including benzodiazepines, anticonvulsants, beta blockers, dopamine agents, antidepressants, muscle relaxants, and others. However, there is little, if any, evidence for their respective and comparative efficacies with each other and when compared to a placebo. A multiyear systematic review to investigate the evidence for drug treatments in sleep bruxism published in 2014 ("Pharmacotherapy for Sleep Bruxism". Macedo, et al.) found "insufficient evidence on the effectiveness of pharmacotherapy for the treatment of sleep bruxism." Specific drugs that have been studied in sleep bruxism are