Half sphere exposure used in predicting discontinuous B-cell epitopes. Song et al. have developed an online webserver termed HSEpred to predict half-sphere exposure from protein primary sequences. HSEpred server can achieve the correlation coefficients of 0.72 and 0.68 between the predicted and observed HSE-up and HSE-down measures, respectively, when evaluated on a well-prepared non-homologous protein structure dataset. Moreover, residue contact number (CN) can also be accurately predicted by HSEpred webserver using the summation of the predicted HSE-up and HSE-down values, which has further enlarged the application of this new solvent exposure measure. Recently, Heffernan et al. has developed the most accurate predictor for
What Is This Thing Called Love? (short story) with aliens and sex. According to Asimov the article was mostly based on "Marvel" since its contents had been the raciest. Cele Goldsmith Lalli, editor of "Amazing Stories", requested a satire of the "Playboy" article. Asimov set out to write a story telling how a sex-interested alien and humans might "really" interact. The story appeared in the March 1961 issue of "Amazing" as "Playboy and the Slime God", but when Asimov included it in his 1969 collection "Nightfall and Other Stories" he retitled it "What Is This Thing Called Love?" Goldsmith Lalli rewrote the story's last three paragraphs, a change