Schistosomiasis artesunate, or mefloquine. A Cochrane review found tentative evidence that when used alone, metrifonate was as effective as praziquantel. Another agent, mefloquine, which has previously been used to treat and prevent malaria, was recognised in 2008–2009 to be effective against "Schistosoma". Historically, antimony potassium tartrate remained the treatment of choice for schistosomiasis until the development of praziquantel in the 1980s. The disease is found in tropical countries in Africa, the Caribbean, eastern South America, Southeast Asia, and the Middle East. "S. mansoni" is found in parts of South America and the Caribbean, Africa, and the Middle East; "S. haematobium" in
International Association for the Treatment of Sexual Offenders medical treatments, or other psychical interventions. Probation supervision and residential placement are not considered treatment for this specific age group. However, they are still important aspects of intervention with juvenile sexual offenders. Family sometimes is a reason as to why juveniles offend. Some characteristics of the family of a juvenile sexual offender are troubled adolescent behavior, environment (can be either advantage or disadvantage neighborhoods, as in both good or both), and also has shown effects such as use of aggression and/or force. When a professional is deciding on a treatment for the adolescent they need to view the adolescent within