Half sphere exposure used in predicting discontinuous B-cell epitopes. Song et al. have developed an online webserver termed HSEpred to predict half-sphere exposure from protein primary sequences. HSEpred server can achieve the correlation coefficients of 0.72 and 0.68 between the predicted and observed HSE-up and HSE-down measures, respectively, when evaluated on a well-prepared non-homologous protein structure dataset. Moreover, residue contact number (CN) can also be accurately predicted by HSEpred webserver using the summation of the predicted HSE-up and HSE-down values, which has further enlarged the application of this new solvent exposure measure. Recently, Heffernan et al. has developed the most accurate predictor for
Science On a Sphere Science On a Sphere Science On a Sphere (SOS) is a spherical projection system created by NOAA. It presents high-resolution video on a suspended globe rather than a flat screen, with the aim of better representing global phenomena. Animated images of atmospheric storms, climate change, and ocean temperature can be shown on the sphere to explain these complex environmental processes. SOS systems are most frequently installed in science museums, universities, zoos, and research institutions, although new and novel uses for these systems in a variety of presentation spaces and contexts are starting to emerge. The system has been installed in