Acetophenone is also a component of castoreum, the exudate from the castor sacs of the mature beaver. In the late 19th and early 20th centuries, acetophenone was used in medicine. It was marketed as a hypnotic and anticonvulsant under brand name Hypnone. The typical dosage was 0.12 to 0.3 milliliters. It was considered to have superior sedative effects to both paraldehyde and chloral hydrate. In humans, acetophenone is metabolized to benzoic acid, carbonic acid, and acetone. Hippuric acid occurs as an indirect metabolite and its quantity in urine may be used to confirm acetophenone exposure, although other substances, like toluene, also
Animal welfare and rights in South Korea by the Ordinance of the Ministry for Food, Agriculture, Forestry, and Fisheries, such as stunning or gas. The government is to formulate and implement a comprehensive animal welfare plan every five years, including matters related to animal farming. Regarding animal testing, alternatives to animals must be considered, animals less sensitive to pain should be used where possible, anesthetics are required, and lost or abandoned animals which have served humans (e.g. guide dogs) must not be used. The law stipulates that Animal Experimentation Ethics Committees be created in facilities where animals are experimented on. In addition to the Animal Protection Act,