Mefloquine the drug's very long half-life, the Centers for Disease Control originally recommended a mefloquine dosage of 250 mg every two weeks; however, this caused an unacceptably high malaria rate in the Peace Corps volunteers who participated in the approval study, so the drug regimen was switched to once a week. The first randomized, controlled trial on a mixed population was performed in 2001. Prophylaxis with mefloquine was compared to prophylaxis with atovaquone-proguanil. Roughly 67% of participants in the mefloquine arm reported greater than or equal to one adverse event, vs 71% in the atovaquone-proguanil arm. In the mefloquine arm, 5%
People for the Ethical Treatment of Animals People for the Ethical Treatment of Animals People for the Ethical Treatment of Animals (PETA ; stylized PeTA) is an American animal rights organization based in Norfolk, Virginia, and led by Ingrid Newkirk, its international president. A nonprofit corporation with nearly 400 employees, it claims that it has 6.5 million members and supporters, in addition to claiming that it is the largest animal rights group in the world. Its slogan is "Animals are not ours to eat, wear, experiment on, use for entertainment, or abuse in any other way." Founded in March 1980 by Newkirk and fellow animal rights activist