Schistosomiasis artesunate, or mefloquine. A Cochrane review found tentative evidence that when used alone, metrifonate was as effective as praziquantel. Another agent, mefloquine, which has previously been used to treat and prevent malaria, was recognised in 2008–2009 to be effective against "Schistosoma". Historically, antimony potassium tartrate remained the treatment of choice for schistosomiasis until the development of praziquantel in the 1980s. The disease is found in tropical countries in Africa, the Caribbean, eastern South America, Southeast Asia, and the Middle East. "S. mansoni" is found in parts of South America and the Caribbean, Africa, and the Middle East; "S. haematobium" in
International Association for the Treatment of Sexual Offenders changes as well. A "one size fits all" approach can not be used because youth who have committed sexual crimes are a diverse population, meaning they are all different in numerous ways. Treatment response to sexual abuse by juveniles is based on relapsed prevention, offense cycle, and presumption of sexual dividends. Some research coming out suggests that the successful treatments are those which include community-based and involve supportive adults in the youth's life. Something to keep in mind is label the behavior of the youth, not their identity, because it helps to make sure that youths do not develop a