Schistosomiasis artesunate, or mefloquine. A Cochrane review found tentative evidence that when used alone, metrifonate was as effective as praziquantel. Another agent, mefloquine, which has previously been used to treat and prevent malaria, was recognised in 2008–2009 to be effective against "Schistosoma". Historically, antimony potassium tartrate remained the treatment of choice for schistosomiasis until the development of praziquantel in the 1980s. The disease is found in tropical countries in Africa, the Caribbean, eastern South America, Southeast Asia, and the Middle East. "S. mansoni" is found in parts of South America and the Caribbean, Africa, and the Middle East; "S. haematobium" in
People for the Ethical Treatment of Animals which it seeks to improve the treatment of, and also advocates for improvements for companion animals. In 2016, PETA Asia-Pacific shocked customers with a fake pop-up shop in Bangkok called The Leather Work, which seemed to specialize in "luxury" leather bags, shoes, and other clothing and accessories. Inside the items, though, were what appeared to be the gory flesh, sinews, beating hearts, and blood of animals slaughtered for such items. According to the "Asian Correspondent", the stunt caused shoppers to jump back and gasp in horror. PETA claims "to have found workers in crocodile farms 'sawing open reptile's necks while