Half sphere exposure both HSEα and HSEβ based on a big dataset by using multiple-step iterative deep neural-network learning. The predicted HSEa shows a higher correlation coefficient to the stability change by residue mutants than predicted HSEβ and ASA. The results, together with its easy Ca-atom-based calculation, highlight the potential usefulness of predicted HSEa for protein structure prediction and refinement as well as function prediction. Half sphere exposure Half Sphere Exposure (HSE) is a protein solvent exposure measure that was first introduced by . Like all solvent exposure measures it measures how buried amino acid residues are in a protein. It is found
Sphere of annihilation "sphere of annihilation" remains in place, but a character can move it through mental effort. Mordicai Knode of Tor.com called the item "the best minor artifact" in the game. Sphere of annihilation A sphere of annihilation is a fictional magic item in the "Dungeons & Dragons" fantasy role-playing game. The sphere of annihilation appeared in first edition "Advanced Dungeons & Dragons" in the original 1979 "Dungeon Master's Guide". It also appeared in second edition "Advanced Dungeons & Dragons" in the 2nd edition "Dungeon Master's Guide" (1989). The sphere of annihilation appeared in the third edition "Dungeon Master's Guide" (2000), classified