Mefloquine drug composed of only the (+)-enantiomer. Mefloquine alters cholinergic synaptic transmission through both postsynaptic and presynaptic actions. The postsynaptic action to inhibit acetylcholinesterase changes transmission across synapses in the brain. Mefloquine Mefloquine, sold under the brand names Lariam among others, is a medication used to prevent or treat malaria. When used for prevention it is taken once a week and should be started one or two weeks before potential exposure and continued for four weeks after potential exposure. It can be used to treat mild or moderate malaria but should not be used to treat severe malaria. It is taken
This Is What You Came For among artists to 73). "This Is What You Came For" became Rihanna's 25th and Harris's fourth number one on the Hot Dance Club Songs Chart, where it became the first song since 2013's "Wake Me Up" to stay at number one for two weeks. As of October 2016, the single has sold 1.2 million copies in the United States. "This Is What You Came For" debuted at number one on the Scottish Singles Chart, and peaked at number one in Australia, Canada and Ireland. The song also reached the top 10 in Germany, Ireland, New Zealand, Switzerland, Belgium, Denmark, Finland,