Mefloquine during the study. Mefloquine was the first Public-Private Venture (PPV) between the US Department of Defense and a pharmaceutical company. WRAIR transferred all its phase I and phase II clinical trial data to Hoffman LaRoche and Smith Kline. FDA approval as a treatment for malaria was swift. Most notably, phase III safety and tolerability trials were skipped. The drug was first approved and sold on a commercial basis in Switzerland in 1985. However, mefloquine was not approved by the FDA for prophylactic use until 1989. This approval was based primarily on compliance, while safety and tolerability were overlooked. Because of
Here Is What Is some of the tracks ("Beauty" and "Chest of Drawers") are conversations with Brian Eno. All songs written by Daniel Lanois unless otherwise noted. "Where Will I Be" is a new version of a song which had been previously released on Emmylou Harris' album "Wrecking Ball" in 1995. "Lovechild" and "Sacred And Secular" tracks incorporates, respectively, the pedal steel guitar melody used in "Carla", on Belladonna album, and the pedal steel guitar melody used in "Transmitter", on Shine album. Here Is What Is Here Is What Is is the fifth studio album by Canadian songwriter and record producer Daniel Lanois. It