Half sphere exposure Half sphere exposure Half Sphere Exposure (HSE) is a protein solvent exposure measure that was first introduced by . Like all solvent exposure measures it measures how buried amino acid residues are in a protein. It is found by counting the number of amino acid neighbors within two half spheres of chosen radius around the amino acid. The calculation of HSE is found by dividing a contact number (CN) sphere in two halves by the plane perpendicular to the Cβ-Cα vector. This simple division of the CN sphere results in two strikingly different measures, HSE-up and HSE-down. HSE-up is defined
Sphere (novel) film by Andrei Tarkovsky". Reviews were mostly positive for the novel. "The New York Times" Robin McKinley said, "Part of the fun of "Sphere" is that it keeps you going even when you're pretty sure of what will happen next." Sphere (novel) Sphere is a novel written by author Michael Crichton that was published in 1987. The novel was adapted into the film "Sphere" in 1998. The story follows Norman Johnson, a psychologist engaged by the United States Navy, who joins a team of scientists assembled to examine a spacecraft of unknown origin discovered on the bottom of the Pacific