Mefloquine drug composed of only the (+)-enantiomer. Mefloquine alters cholinergic synaptic transmission through both postsynaptic and presynaptic actions. The postsynaptic action to inhibit acetylcholinesterase changes transmission across synapses in the brain. Mefloquine Mefloquine, sold under the brand names Lariam among others, is a medication used to prevent or treat malaria. When used for prevention it is taken once a week and should be started one or two weeks before potential exposure and continued for four weeks after potential exposure. It can be used to treat mild or moderate malaria but should not be used to treat severe malaria. It is taken
The Old Blue Mayor She Ain't What She Used to Be tonight, flock to Marge not because she’s clearly a better candidate and person than perennially elected, womanizing, cartoonishly corrupt Diamond Joe Quimby, but because resident political operative Lindsey Naegle convinces her to use Professor Frink’s micro-targeted campaigning." "The Old Blue Mayor She Ain't What She Used to Be" scored a 1.9 rating with a 7 share and was watched by 4.75 million people, making it Fox's highest rated show of the night. The Old Blue Mayor She Ain't What She Used to Be "The Old Blue Mayor She Ain't What She Used to Be" is the sixth episode of the