Half sphere exposure both HSEα and HSEβ based on a big dataset by using multiple-step iterative deep neural-network learning. The predicted HSEa shows a higher correlation coefficient to the stability change by residue mutants than predicted HSEβ and ASA. The results, together with its easy Ca-atom-based calculation, highlight the potential usefulness of predicted HSEa for protein structure prediction and refinement as well as function prediction. Half sphere exposure Half Sphere Exposure (HSE) is a protein solvent exposure measure that was first introduced by . Like all solvent exposure measures it measures how buried amino acid residues are in a protein. It is found
Bernal sphere optimum mass-efficiency at providing radiation shielding. O'Neill envisioned the next generation of space habitat as a larger version of "Island One". "Island Two" would be approximately 1800 meters in diameter, yielding an equatorial circumference of nearly six and a half kilometers (four miles). The size was driven by economics; the habitat was to be small enough to allow for efficient transportation within the habitat and large enough to support an efficient industrial base. Bernal sphere A Bernal sphere is a type of space habitat intended as a long-term home for permanent residents, first proposed in 1929 by John Desmond Bernal.