Half sphere exposure both HSEα and HSEβ based on a big dataset by using multiple-step iterative deep neural-network learning. The predicted HSEa shows a higher correlation coefficient to the stability change by residue mutants than predicted HSEβ and ASA. The results, together with its easy Ca-atom-based calculation, highlight the potential usefulness of predicted HSEa for protein structure prediction and refinement as well as function prediction. Half sphere exposure Half Sphere Exposure (HSE) is a protein solvent exposure measure that was first introduced by . Like all solvent exposure measures it measures how buried amino acid residues are in a protein. It is found
Bloch sphere sphere is also known as the Poincaré sphere and specifically represents different types of polarizations. Six common polarization types exist and are called Jones Vectors. Indeed Henri Poincaré was the first to suggest the use of this kind of geometrical representation at the end of 19th century, as a three-dimensional representation of Stokes parameters. The natural metric on the Bloch sphere is the Fubini–Study metric. The mapping from the unit 3-sphere in the two-dimensional state space ℂ to the Bloch sphere is the Hopf fibration. Given an orthonormal basis, any pure state formula_3 of a two-level quantum system can be