Half sphere exposure used in predicting discontinuous B-cell epitopes. Song et al. have developed an online webserver termed HSEpred to predict half-sphere exposure from protein primary sequences. HSEpred server can achieve the correlation coefficients of 0.72 and 0.68 between the predicted and observed HSE-up and HSE-down measures, respectively, when evaluated on a well-prepared non-homologous protein structure dataset. Moreover, residue contact number (CN) can also be accurately predicted by HSEpred webserver using the summation of the predicted HSE-up and HSE-down values, which has further enlarged the application of this new solvent exposure measure. Recently, Heffernan et al. has developed the most accurate predictor for
What Is This Thing Called Love? (short story) What Is This Thing Called Love? (short story) "What Is This Thing Called Love?" is a science fiction short story by Isaac Asimov. The story was requested by Cele Goldsmith Lalli, editor of "Amazing Stories", as a satire of an article in "Playboy" called "Girls of the Slime God" which had suggested that pulp science fiction stories were concerned with aliens and sex. The story appeared in the March 1961 issue of "Amazing" as "Playboy and the Slime God", but Asimov later retitled it "What Is This Thing Called Love?" According to Asimov, in "1938-39 ... for some half a