Mefloquine the drug's very long half-life, the Centers for Disease Control originally recommended a mefloquine dosage of 250 mg every two weeks; however, this caused an unacceptably high malaria rate in the Peace Corps volunteers who participated in the approval study, so the drug regimen was switched to once a week. The first randomized, controlled trial on a mixed population was performed in 2001. Prophylaxis with mefloquine was compared to prophylaxis with atovaquone-proguanil. Roughly 67% of participants in the mefloquine arm reported greater than or equal to one adverse event, vs 71% in the atovaquone-proguanil arm. In the mefloquine arm, 5%
Association for the Treatment of Sexual Abusers of sexual abuse through effective treatment and management of sex offenders. It has approximately 3,000 members from 26 countries, with chapters throughout the United States and in Utrecht, Netherlands. Members include researchers, treatment providers, corrections officials, attorneys, law enforcement officers, and students. ATSA hosts the world's largest annual conference and leading educational venue for individuals working on issues related to the research, treatment, and management of sexual abuse. Conference locations vary each year. The official journal of ATSA is "Sexual Abuse", produced eight times a year. According to the Institute for Scientific Information, the peer-reviewed journal's 2016 impact factor was