Half sphere exposure Half sphere exposure Half Sphere Exposure (HSE) is a protein solvent exposure measure that was first introduced by . Like all solvent exposure measures it measures how buried amino acid residues are in a protein. It is found by counting the number of amino acid neighbors within two half spheres of chosen radius around the amino acid. The calculation of HSE is found by dividing a contact number (CN) sphere in two halves by the plane perpendicular to the Cβ-Cα vector. This simple division of the CN sphere results in two strikingly different measures, HSE-up and HSE-down. HSE-up is defined
What Is a Nation? to the reasons based on race, geography, history and so on. They argue that Renan maintains his intellectual background but subtly, i.e. the arguments he explicitly used in "What is a Nation?" are not consistent with his thinking. The concept of "daily plebiscite" would be ambiguous. They argue that the definition is an opportunist idealization and it should be interpreted within the Franco-Prussian War and in the midst of the dispute concerning the Alsace-Lorraine region. What Is a Nation? "What is a Nation?" ("Qu'est-ce qu'une nation?") is an 1882 lecture by French historian Ernest Renan (1823–1892), known for the statements