Mefloquine the drug's very long half-life, the Centers for Disease Control originally recommended a mefloquine dosage of 250 mg every two weeks; however, this caused an unacceptably high malaria rate in the Peace Corps volunteers who participated in the approval study, so the drug regimen was switched to once a week. The first randomized, controlled trial on a mixed population was performed in 2001. Prophylaxis with mefloquine was compared to prophylaxis with atovaquone-proguanil. Roughly 67% of participants in the mefloquine arm reported greater than or equal to one adverse event, vs 71% in the atovaquone-proguanil arm. In the mefloquine arm, 5%
What Is Love and produced by German music producer and composer Dee Dee Halligan (Dieter Lünstedt a.k.a. Tony Hendrik) and Junior Torello (Karin Hartmann-Eisenblätter a.k.a. Karin van Haaren) of Coconut Records in Cologne. They were waiting for the right singer for the song. Trinidadian-born singer Nestor Alexander Haddaway was then chosen to sing it. He used to work as a producer, dancer and choreographer before he was signed to Coconut Records. In a 2012 interview Haddaway said about the making of "What Is Love": "What Is Love" was released in Europe in May 1993 and in the US in August 1993. It peaked