Acetophenone is also a component of castoreum, the exudate from the castor sacs of the mature beaver. In the late 19th and early 20th centuries, acetophenone was used in medicine. It was marketed as a hypnotic and anticonvulsant under brand name Hypnone. The typical dosage was 0.12 to 0.3 milliliters. It was considered to have superior sedative effects to both paraldehyde and chloral hydrate. In humans, acetophenone is metabolized to benzoic acid, carbonic acid, and acetone. Hippuric acid occurs as an indirect metabolite and its quantity in urine may be used to confirm acetophenone exposure, although other substances, like toluene, also
Animal welfare and rights in Sweden 2014 survey of 1000 Swedes commissioned by Animal Rights Sweden, ten percent of respondents identified as either vegan or vegetarian. This was a four-percent increase from a survey five years earlier. In 2012, 982,842 animals were used in research in Sweden. If fish used in sample-based fishery surveys are included, 5,535,458 animals were used. An undercover investigation of 15 Swedish mink farms by activist group Animal Rights Alliance found behavior indicative of high stress and frustration on 13 of 15 farms; infected, unconscious, convulsive, maimed, and dead animals; cages with large amounts of feces piled up on 67% of farms;