Antimalarial medication multi-drug resistant "P. falciparum". It is a very potent blood schizonticide with a long half-life. It is thought to act by forming toxic heme complexes that damage parasitic food vacuoles. Mefloquine is effective in prophylaxis and for acute therapy. It is now used solely for the prevention of resistant strains of "P. falciparum" (usually combined with Artesunate) despite being effective against "P. vivax", "P. ovale" and "P. marlariae". Chloroquine/proguanil or sulfa drug-pyrimethamine combinations should be used in all other plasmodia infections. The major commercial manufacturer of mefloquine-based malaria treatment is Roche Pharmaceuticals, which markets the drug under the trade name
Ball of Confusion (That's What the World Is Today) Ball of Confusion (That's What the World Is Today) "Ball of Confusion (That's What the World Is Today)" is a 1970 hit single for The Temptations. It was released on the Gordy (Motown) label, and written by Norman Whitfield and Barrett Strong. The song was used to anchor the 1970 "Greatest Hits II" LP. The song reached #3 on the US pop charts and #2 on the US R&B charts. "Billboard" ranked the record as the No. 24 song of 1970. It reached no. 7 in the UK Singles Chart. Although a nearly eleven minute long backing track was recorded