Mefloquine one. Plasma concentrations of the (–)-enantiomer are significantly higher than those for the (+)-enantiomer, and the pharmacokinetics between the two enantiomers are significantly different. The (+)-enantiomer has a shorter half-life than the (–)-enantiomer. According to some research, the (+)-enantiomer is more effective in treating malaria, and the (–)-enantiomer specifically binds to adenosine receptors in the central nervous system, which may explain some of its psychotropic effects. Mefloquine was formulated at Walter Reed Army Institute of Research (WRAIR) in the 1970s shortly after the end of the Vietnam war. Mefloquine was number 142,490 of a total of 250,000 antimalarial compounds screened
Community Alliance for the Ethical Treatment of Youth Representatives, but was not acted upon in the Senate and did not become law. Community Alliance for the Ethical Treatment of Youth The Community Alliance For the Ethical Treatment of Youth (CAFETY) is an advocacy group for people enrolled in residential treatment programs for at-risk teenagers. The group's mission includes advocating for access to advocates, due process, alternatives to aversive behavioral interventions, and alternatives to restraints and seclusion for young people in treatment programs. They have also called for the routine reporting of abuse in residential treatment programs, as well as federal government oversight and regulation of residential treatment programs.