Mefloquine one. Plasma concentrations of the (–)-enantiomer are significantly higher than those for the (+)-enantiomer, and the pharmacokinetics between the two enantiomers are significantly different. The (+)-enantiomer has a shorter half-life than the (–)-enantiomer. According to some research, the (+)-enantiomer is more effective in treating malaria, and the (–)-enantiomer specifically binds to adenosine receptors in the central nervous system, which may explain some of its psychotropic effects. Mefloquine was formulated at Walter Reed Army Institute of Research (WRAIR) in the 1970s shortly after the end of the Vietnam war. Mefloquine was number 142,490 of a total of 250,000 antimalarial compounds screened
People for the Ethical Treatment of Animals respect to groups engaged in actual fieldwork is unnecessarily divisive and hurts animal advocacy. People for the Ethical Treatment of Animals People for the Ethical Treatment of Animals (PETA ; stylized PeTA) is an American animal rights organization based in Norfolk, Virginia, and led by Ingrid Newkirk, its international president. A nonprofit corporation with nearly 400 employees, it claims that it has 6.5 million members and supporters, in addition to claiming that it is the largest animal rights group in the world. Its slogan is "Animals are not ours to eat, wear, experiment on, use for entertainment, or abuse in