Mefloquine during the study. Mefloquine was the first Public-Private Venture (PPV) between the US Department of Defense and a pharmaceutical company. WRAIR transferred all its phase I and phase II clinical trial data to Hoffman LaRoche and Smith Kline. FDA approval as a treatment for malaria was swift. Most notably, phase III safety and tolerability trials were skipped. The drug was first approved and sold on a commercial basis in Switzerland in 1985. However, mefloquine was not approved by the FDA for prophylactic use until 1989. This approval was based primarily on compliance, while safety and tolerability were overlooked. Because of
Fools Gold/What the World Is Waiting For Fools Gold/What the World Is Waiting For "Fools Gold" and "What the World Is Waiting For" are two songs by British rock band the Stone Roses. They were released together as a double A-side single on 13 November 1989 through Silvertone Records. "Fools Gold" would go on to appear on certain non-UK versions of their self-titled debut studio album (1989). "Fools Gold" became the band's biggest commercial hit at the time. It was their first single to reach the top ten of the UK Singles Chart and stayed in the top-75 for fourteen weeks, peaking at number eight. "Fools Gold"