Half sphere exposure Half sphere exposure Half Sphere Exposure (HSE) is a protein solvent exposure measure that was first introduced by . Like all solvent exposure measures it measures how buried amino acid residues are in a protein. It is found by counting the number of amino acid neighbors within two half spheres of chosen radius around the amino acid. The calculation of HSE is found by dividing a contact number (CN) sphere in two halves by the plane perpendicular to the Cβ-Cα vector. This simple division of the CN sphere results in two strikingly different measures, HSE-up and HSE-down. HSE-up is defined
What Is a Man Without a Moustache? 62 based on five reviews from critics. In a review for "Variety" magazine, critic Deborah Young called "What Is a Man Without a Moustache?" "an entertaining romantic comedy" and a "good-humored film" while, on the other hand, noting that the film should be better received by local and regional audiences due to its story being "a hard sell abroad". Author and film critic Michael Atkinson, writing for "The Village Voice", expressed his divided opinion that the film "is not remarkable or ingenious" but that it still is "adept enough for a pass on." Critic Nathan Lee of "The New York