Half sphere exposure both HSEα and HSEβ based on a big dataset by using multiple-step iterative deep neural-network learning. The predicted HSEa shows a higher correlation coefficient to the stability change by residue mutants than predicted HSEβ and ASA. The results, together with its easy Ca-atom-based calculation, highlight the potential usefulness of predicted HSEa for protein structure prediction and refinement as well as function prediction. Half sphere exposure Half Sphere Exposure (HSE) is a protein solvent exposure measure that was first introduced by . Like all solvent exposure measures it measures how buried amino acid residues are in a protein. It is found
Celestial Sphere Woodrow Wilson Memorial and the ideals of the United Nations. Celestial Sphere Woodrow Wilson Memorial The grounds of the Palais des Nations (seat of the United Nations Office at Geneva) contain many fine objects donated by member states of the United Nations, private sponsors and artists. The Celestial Sphere (also known as the Armillary Sphere) in the Ariana Park of the Palais des Nations is the best-known of these. The huge - over four meter diameter - "Celestial Sphere" is the chef d'oeuvre of the American sculptor Paul Manship (1885–1966). It was donated in 1939 by the Woodrow Wilson Foundation to what was