Half sphere exposure both HSEα and HSEβ based on a big dataset by using multiple-step iterative deep neural-network learning. The predicted HSEa shows a higher correlation coefficient to the stability change by residue mutants than predicted HSEβ and ASA. The results, together with its easy Ca-atom-based calculation, highlight the potential usefulness of predicted HSEa for protein structure prediction and refinement as well as function prediction. Half sphere exposure Half Sphere Exposure (HSE) is a protein solvent exposure measure that was first introduced by . Like all solvent exposure measures it measures how buried amino acid residues are in a protein. It is found
What Is This Thing Called Love? (short story) What Is This Thing Called Love? (short story) "What Is This Thing Called Love?" is a science fiction short story by Isaac Asimov. The story was requested by Cele Goldsmith Lalli, editor of "Amazing Stories", as a satire of an article in "Playboy" called "Girls of the Slime God" which had suggested that pulp science fiction stories were concerned with aliens and sex. The story appeared in the March 1961 issue of "Amazing" as "Playboy and the Slime God", but Asimov later retitled it "What Is This Thing Called Love?" According to Asimov, in "1938-39 ... for some half a