Drug injection can lead to a dependency by both physical and psychological means — and develops more quickly than with other methods of taking drugs. In recreational-use drug culture, preparation may include mixing the powdered drug with water to create an aqueous solution, and then the solution is injected. This act is often colloquially referred to as "slamming", "shooting [up]", “smashing”, "banging", "pinning", or "jacking-up", often depending on the specific drug subculture in which the term is used (i.e. heroin, cocaine, or methamphetamine). There are a variety of reasons why drugs would be more attractive to inject rather than take through other
International Council for Harmonisation of Technical Requirements for Pharmaceuticals for Human Use technical guidelines and requirements for product registration. Harmonisation would lead to a more economical use of human, non-human animal and material resources, and the elimination of unnecessary delay in the global development and availability of new medicines while maintaining safeguards on quality, safety, and efficacy, and regulatory obligations to protect public health. ICH guidelines have been adopted as law in several countries, but are only used as guidance for the U.S. Food and Drug Administration. In the 1980s, what is today the European Union began harmonising regulatory requirements. In 1989, Europe, Japan, and the United States began creating plans for