Half sphere exposure Half sphere exposure Half Sphere Exposure (HSE) is a protein solvent exposure measure that was first introduced by . Like all solvent exposure measures it measures how buried amino acid residues are in a protein. It is found by counting the number of amino acid neighbors within two half spheres of chosen radius around the amino acid. The calculation of HSE is found by dividing a contact number (CN) sphere in two halves by the plane perpendicular to the Cβ-Cα vector. This simple division of the CN sphere results in two strikingly different measures, HSE-up and HSE-down. HSE-up is defined
Celestial sphere Celestial sphere In astronomy and navigation, the celestial sphere is an abstract sphere that has an arbitrarily large radius and is concentric to Earth. All objects in the sky can be conceived as being projected upon the inner surface of the celestial sphere, which may be centered on Earth or the observer. If centered on the observer, half of the sphere would resemble a hemispherical screen over the observing location. The celestial sphere is a practical tool for spherical astronomy, allowing astronomers to specify the apparent positions of objects in the sky if their distances are unknown or irrelevant. In