Mefloquine the drug's very long half-life, the Centers for Disease Control originally recommended a mefloquine dosage of 250 mg every two weeks; however, this caused an unacceptably high malaria rate in the Peace Corps volunteers who participated in the approval study, so the drug regimen was switched to once a week. The first randomized, controlled trial on a mixed population was performed in 2001. Prophylaxis with mefloquine was compared to prophylaxis with atovaquone-proguanil. Roughly 67% of participants in the mefloquine arm reported greater than or equal to one adverse event, vs 71% in the atovaquone-proguanil arm. In the mefloquine arm, 5%
International Association for the Treatment of Sexual Offenders assessment and/or treatment of a child or juvenile who has committed a sexual offense: International Association for the Treatment of Sexual Offenders The International Association for the Treatment of Sexual Offenders (IATSO) is an international non-profit professional organization based in Vienna committed to the promotion of research of and treatment for sex offenders throughout the world. IATSO was founded in March 24, 1998 in Caracas, Venezuela during the 5th International Conference on the Treatment of Sex Offenders. They publish "Sex Offender Treatment", an international peer-reviewed journal open to all scientists and practitioners researching sexual abuse. In 2014 the first ever