Phytoene desaturase (lycopene-forming) Phytoene desaturase (lycopene-forming) Phytoene desaturase (lycopene-forming) (CrtI, "four-step phytoene desaturase") (, "15-cis-phytoene:acceptor oxidoreductase (lycopene-forming)") are enzymes found in archaea, bacteria and fungi that are involved in carotenoid biosynthesis. They catalyze the conversion of colorless 15-"cis"-phytoene into a bright red lycopene in a biochemical pathway called the poly-trans pathway. The same process in plants and cyanobacteria utilizes four separate enzymes in a poly-cis pathway. Bacterial phytoene desaturases were shown to require FAD as a cofactor for their function. During the chemical reaction in total four additional double bonds are introduced into phytoene: In 2000 it was discovered that the gene insertion
Blue Is the Warmest Colour the Warmest Color" through The Criterion Collection on 25 February 2014. As "Blue Is the Warmest Colour", the film was also released on DVD and Blu-ray Disc in Canada on 25 February 2014 by Mongrel Media, in the United Kingdom on 17 March 2014 by Artificial Eye and on 18 June 2014 in Australia by Transmission Films. In Brazil, Blu-ray manufacturing companies Sonopress and Sony DADC are refusing to produce the film because of its content. The distributor is struggling to reverse this situation. "Blue Is the Warmest Colour" grossed a worldwide total of $19,492,879. During its opening in France,