Acetophenone is also a component of castoreum, the exudate from the castor sacs of the mature beaver. In the late 19th and early 20th centuries, acetophenone was used in medicine. It was marketed as a hypnotic and anticonvulsant under brand name Hypnone. The typical dosage was 0.12 to 0.3 milliliters. It was considered to have superior sedative effects to both paraldehyde and chloral hydrate. In humans, acetophenone is metabolized to benzoic acid, carbonic acid, and acetone. Hippuric acid occurs as an indirect metabolite and its quantity in urine may be used to confirm acetophenone exposure, although other substances, like toluene, also
Castor and Pollux revered by the Romans, probably as the result of cultural transmission via the Greek colonies of Magna Graecia in southern Italy. An archaic Latin inscription of the sixth or fifth century BC found at Lavinium, which reads "Castorei Podlouqueique qurois" ("To Castor and Pollux, the Dioskouroi"), suggests a direct transmission from the Greeks; the word "qurois" is virtually a transliteration of the Greek word "κούροις", while "Podlouquei" is effectively a transliteration of the Greek "Πολυδεύκης". The construction of the Temple of Castor and Pollux, located in the Roman Forum at the heart of their city, was undertaken to fulfil a