Acid-free paper durable acid-free paper. Archival paper is meant to be used for publications of high legal, historical, or significant value. In the USA, such paper must also be approved in accordance with the ANSI standards. The international standard for "permanent" paper is ISO 9706 and for "archival" paper, the standard is ISO 11108. Often, cotton rag paper is used for archival purposes, as it is not made from wood-based pulp. Thus, "archival paper" is sometimes broken down into two categories: Acid-free paper Acid-free paper is paper that if infused in water yields a neutral or basic pH (7 or slightly greater).
Acid sphingomyelinase through promoting aggreation of lipoproteins to arterial walls. Inhibition of aSMases is a current thereapuetuic target for the treatment of atherosclerosis. Secreted aSMase may also play a role in Diabetes. Inflammation induced S-SMase activation may contribute to insulin resistance through the increased generation of ceramide. Acid sphingomyelinase Acid sphingomyelinase is one of the enzymes that make up the sphingomyelinase (SMase) family, responsible for catalyzing the breakdown of sphingomyelin to ceramide and phosphorylcholine. They are organized into alkaline, neutral, and acidic SMase depending on the pH in which their enzymatic activity is optimal. Acid Sphingomyelinases (aSMases) enzymatic activity can be influenced