Acetophenone is also a component of castoreum, the exudate from the castor sacs of the mature beaver. In the late 19th and early 20th centuries, acetophenone was used in medicine. It was marketed as a hypnotic and anticonvulsant under brand name Hypnone. The typical dosage was 0.12 to 0.3 milliliters. It was considered to have superior sedative effects to both paraldehyde and chloral hydrate. In humans, acetophenone is metabolized to benzoic acid, carbonic acid, and acetone. Hippuric acid occurs as an indirect metabolite and its quantity in urine may be used to confirm acetophenone exposure, although other substances, like toluene, also
Oily fish Oily fish Oily fish have oil in their tissues and in the belly cavity around the gut. Their fillets contain up to 30% oil, although this figure varies both within and between species. Examples include small forage fish, such as sardines, herring and anchovies, and other larger pelagic fish, such as salmon, trout, tuna, swordfish and mackerel. Oily fish can be contrasted with white fish, which contain oil only in the liver, and much less overall than oily fish. Examples of white fish are cod, haddock and flatfish. White fish are usually demersal fish which live on or near the