Mefloquine one. Plasma concentrations of the (–)-enantiomer are significantly higher than those for the (+)-enantiomer, and the pharmacokinetics between the two enantiomers are significantly different. The (+)-enantiomer has a shorter half-life than the (–)-enantiomer. According to some research, the (+)-enantiomer is more effective in treating malaria, and the (–)-enantiomer specifically binds to adenosine receptors in the central nervous system, which may explain some of its psychotropic effects. Mefloquine was formulated at Walter Reed Army Institute of Research (WRAIR) in the 1970s shortly after the end of the Vietnam war. Mefloquine was number 142,490 of a total of 250,000 antimalarial compounds screened
Association for the Treatment of Sexual Abusers Association for the Treatment of Sexual Abusers The Association for the Treatment of Sexual Abusers (ATSA) is an international, multi-disciplinary, non-profit organization dedicated to making society safer by preventing sexual abuse. ATSA promotes sound research, evidence-based practice, informed public policy, and collaborative community strategies that lead to the effective assessment, treatment, and management of individuals who sexually abuse or are at risk to abuse. ATSA sets ethical and practice standards for treatment providers, and provides referrals. The association was incorporated in 1985 and has its headquarters in Beaverton, Oregon, United States. ATSA is an international organization focused on the prevention