Chemical substance made in a laboratory. Other chemical substances commonly encountered in pure form are diamond (carbon), gold, table salt (sodium chloride) and refined sugar (sucrose). However, in practice, no substance is entirely pure, and chemical purity is specified according to the intended use of the chemical. Chemical substances exist as solids, liquids, gases, or plasma, and may change between these phases of matter with changes in temperature or pressure. Chemical substances may be combined or converted to others by means of chemical reactions. Forms of energy, such as light and heat, are not matter, and are thus not "substances" in this
Synthetic diamond "nanocrystalline" and "microcrystalline" diamond, respectively. Synthetic diamond is the hardest known material, where hardness is defined as resistance to indentation. The hardness of synthetic diamond depends on its purity, crystalline perfection and orientation: hardness is higher for flawless, pure crystals oriented to the <nowiki>[</nowiki>111<nowiki>]</nowiki> direction (along the longest diagonal of the cubic diamond lattice). Nanocrystalline diamond produced through CVD diamond growth can have a hardness ranging from 30% to 75% of that of single crystal diamond, and the hardness can be controlled for specific applications. Some synthetic single-crystal diamonds and HPHT nanocrystalline diamonds (see hyperdiamond) are harder than any known