Kype and/or characteristics that could be of importance in inter- and intra-sexual evaluations of individual quality. The size of the kype is believed to determine male spawning frequency. The extinct sabertooth salmon, "Oncorhynchus rastrosus", was first named for its prominent premaxillary dentition. It possesses an enormous conical tooth on each premaxilla. There is no visible kype on the dentary, implying a different strategy for forming mate dominance. Kype A kype is a hook-like secondary sex characteristic which develops at the distal tip of the lower jaw in some male salmonids prior to the spawning season. The structure usually develops in the
Osteonecrosis of the jaw down clots) and shown to be a cause of hypofibrinolysis. Persistent blood clots can lead to congestive blood flow (hyperemia) in bone marrow, impaired blood flow and ischaemia in bone tissue resulting in lack of oxygen (hypoxia), bone cell damage and eventual cell death (apoptosis). Of significance is the fact that the average concentration of cadmium in human bones in the 20th century has increased to about 10 times above the pre-industrial level. The first three cases of bisphosphonate-associated osteonecrosis of the jaw were spontaneously reported to the FDA by an oral surgeon in 2002, with the toxicity being described