Kype Kype A kype is a hook-like secondary sex characteristic which develops at the distal tip of the lower jaw in some male salmonids prior to the spawning season. The structure usually develops in the weeks prior to, and during, migration to the spawning grounds. In addition to the development of the kype, a large depression forms in the two halves of the premaxilla in the upper jaw, allowing the kype to fit into the premaxilla when the mouth is closed. The kype functions as a secondary sexual characteristic and influences the formation of dominance hierarchies at the spawning grounds. The
Osteonecrosis of the jaw is unlikely to occur until this form of ONJ is better understood, there have been clinical reports of some improvement after 6 months or more of complete cessation of bisphosphonate therapy. ONJ is not a new disease: Around 1850 forms of "chemical osteomyelitis" resulting from environmental pollutants, such as lead and the white phosphorus used in early (non-safety) matches (Phossy jaw), as well as from popular medications containing mercury, arsenic or bismuth, were reported in the literature. This disease apparently did not often occur in individuals with good gingival health, and usually targeted the mandible first. It was associated with