Mefloquine one. Plasma concentrations of the (–)-enantiomer are significantly higher than those for the (+)-enantiomer, and the pharmacokinetics between the two enantiomers are significantly different. The (+)-enantiomer has a shorter half-life than the (–)-enantiomer. According to some research, the (+)-enantiomer is more effective in treating malaria, and the (–)-enantiomer specifically binds to adenosine receptors in the central nervous system, which may explain some of its psychotropic effects. Mefloquine was formulated at Walter Reed Army Institute of Research (WRAIR) in the 1970s shortly after the end of the Vietnam war. Mefloquine was number 142,490 of a total of 250,000 antimalarial compounds screened
This Is What You Came For France, Hungary, Italy, the Netherlands, Norway, Portugal and Slovakia. The song has reached the top 10 in all except three of the countries it has charted in. Taylor Swift performed "This is What You Came For" on the piano for the first time live at the United States Grand Prix in Austin, Texas, on 22 October 2016. Swift then performed an acoustic guitar version at the DirecTV Super Saturday Night in Houston, Texas, on 4 February 2017. This Is What You Came For "This Is What You Came For" is a song by Scottish DJ and record producer Calvin Harris,