Half sphere exposure both HSEα and HSEβ based on a big dataset by using multiple-step iterative deep neural-network learning. The predicted HSEa shows a higher correlation coefficient to the stability change by residue mutants than predicted HSEβ and ASA. The results, together with its easy Ca-atom-based calculation, highlight the potential usefulness of predicted HSEa for protein structure prediction and refinement as well as function prediction. Half sphere exposure Half Sphere Exposure (HSE) is a protein solvent exposure measure that was first introduced by . Like all solvent exposure measures it measures how buried amino acid residues are in a protein. It is found
What Is a Man Without a Moustache? 62 based on five reviews from critics. In a review for "Variety" magazine, critic Deborah Young called "What Is a Man Without a Moustache?" "an entertaining romantic comedy" and a "good-humored film" while, on the other hand, noting that the film should be better received by local and regional audiences due to its story being "a hard sell abroad". Author and film critic Michael Atkinson, writing for "The Village Voice", expressed his divided opinion that the film "is not remarkable or ingenious" but that it still is "adept enough for a pass on." Critic Nathan Lee of "The New York