Mefloquine the drug's very long half-life, the Centers for Disease Control originally recommended a mefloquine dosage of 250 mg every two weeks; however, this caused an unacceptably high malaria rate in the Peace Corps volunteers who participated in the approval study, so the drug regimen was switched to once a week. The first randomized, controlled trial on a mixed population was performed in 2001. Prophylaxis with mefloquine was compared to prophylaxis with atovaquone-proguanil. Roughly 67% of participants in the mefloquine arm reported greater than or equal to one adverse event, vs 71% in the atovaquone-proguanil arm. In the mefloquine arm, 5%
International Association for the Treatment of Sexual Offenders medical treatments, or other psychical interventions. Probation supervision and residential placement are not considered treatment for this specific age group. However, they are still important aspects of intervention with juvenile sexual offenders. Family sometimes is a reason as to why juveniles offend. Some characteristics of the family of a juvenile sexual offender are troubled adolescent behavior, environment (can be either advantage or disadvantage neighborhoods, as in both good or both), and also has shown effects such as use of aggression and/or force. When a professional is deciding on a treatment for the adolescent they need to view the adolescent within