Mefloquine during the study. Mefloquine was the first Public-Private Venture (PPV) between the US Department of Defense and a pharmaceutical company. WRAIR transferred all its phase I and phase II clinical trial data to Hoffman LaRoche and Smith Kline. FDA approval as a treatment for malaria was swift. Most notably, phase III safety and tolerability trials were skipped. The drug was first approved and sold on a commercial basis in Switzerland in 1985. However, mefloquine was not approved by the FDA for prophylactic use until 1989. This approval was based primarily on compliance, while safety and tolerability were overlooked. Because of
Israel Center for the Treatment of Psychotrauma Israel Center for the Treatment of Psychotrauma The Israel Center for the Treatment of Psychotrauma (ICTP) affiliated with Herzog Hospital in Jerusalem, Israel, is a community-based trauma center The Israel Center for the Treatment of Psychotrauma was established in 1989 to improve the level of trauma-related services in Israel and around the world. ICTP has developed a comprehensive range of clinical and community-based services. ICTP is today involved in the research and treatment of the widespread effects of trauma caused by terrorism, war and natural disaster. ICTP has been active in its present form since 1989, but draws on a