Mefloquine in "Pfmdr1" copy number. Mefloquine is contraindicated in those with a previous history of seizures or a recent history of psychiatric disorders. Severe side effects requiring hospitalization are rare. Compared to other malaria prophylaxis regimens, mefloqinone may produce more side effects in non-pregnant travelers. In pregnant travelers, it appears to pose minimal risk to the fetus. In 2013 the United States Food and Drug Administration added a boxed warning to the U.S. label of mefloquine regarding the potential for neuropsychiatric side effects that may persist even after discontinuing administration of the drug. Psychiatric effects include nightmares, visual and auditory hallucinations,
Hyperbaric treatment schedules has shown success over the years. IWR is not without risk and should be undertaken with certain precautions. IWR would only be suitable for an organised and disciplined group of divers with suitable equipment and practical training in the procedure. Treatment of decompression sickness, arterial gas embolism, and other medical applications. The type of chamber which can be used depends on the maximum pressure required for the schedule, and what gases are used for treatment. Most treatment protocols for diving injuries require an attendant in the chamber, and a medical lock to transfer medical supplies into the chamber while under