Mefloquine during the study. Mefloquine was the first Public-Private Venture (PPV) between the US Department of Defense and a pharmaceutical company. WRAIR transferred all its phase I and phase II clinical trial data to Hoffman LaRoche and Smith Kline. FDA approval as a treatment for malaria was swift. Most notably, phase III safety and tolerability trials were skipped. The drug was first approved and sold on a commercial basis in Switzerland in 1985. However, mefloquine was not approved by the FDA for prophylactic use until 1989. This approval was based primarily on compliance, while safety and tolerability were overlooked. Because of
Cute Is What We Aim For to finish up high school and after that I was like, 'Wow, I miss playing music.' I was blessed enough to get that opportunity again." However, Cimato left the band once again in March 2008. It was announced that Dave Melillo would play bass until further notice. In 2008, Cute Is What We Aim For entered the studio to record with producer John Feldmann. "Rotation" debuted at #21 on the U.S. Billboard 200 albums chart selling around 22,000 copies. In 2010, it was announced that the band Cute Is What We Aim For lost all of its members except for