Acetophenone is also a component of castoreum, the exudate from the castor sacs of the mature beaver. In the late 19th and early 20th centuries, acetophenone was used in medicine. It was marketed as a hypnotic and anticonvulsant under brand name Hypnone. The typical dosage was 0.12 to 0.3 milliliters. It was considered to have superior sedative effects to both paraldehyde and chloral hydrate. In humans, acetophenone is metabolized to benzoic acid, carbonic acid, and acetone. Hippuric acid occurs as an indirect metabolite and its quantity in urine may be used to confirm acetophenone exposure, although other substances, like toluene, also
Castor Oyl prominent appearance in the series is as a member of Popeye's orchestra in the 1935 short "The Spinach Overture". In the 1980 film directed by Robert Altman, Castor is a key character, and is played by actor Donovan Scott. In the film, however, he is made Olive's younger brother and is considerably less sophisticated than his comic strip counterpart. Castor Oyl is named after castor oil, a medicine often given to children for various ailments until the mid 20th century. His mother Nana's name derives from "banana oil," an epithet similar to "baloney." His father Cole's name derives from "coal