Acetophenone is also a component of castoreum, the exudate from the castor sacs of the mature beaver. In the late 19th and early 20th centuries, acetophenone was used in medicine. It was marketed as a hypnotic and anticonvulsant under brand name Hypnone. The typical dosage was 0.12 to 0.3 milliliters. It was considered to have superior sedative effects to both paraldehyde and chloral hydrate. In humans, acetophenone is metabolized to benzoic acid, carbonic acid, and acetone. Hippuric acid occurs as an indirect metabolite and its quantity in urine may be used to confirm acetophenone exposure, although other substances, like toluene, also
Castor and Pollux from Sparta, at a shrine known as the "Meneláeion" where Helen, Menelaus, Castor and Pollux were all said to be buried. Castor himself was also venerated in the region of Kastoria in northern Greece. They were commemorated both as gods on Olympus worthy of holocaust, and as deceased mortals in Hades, whose spirits had to be propitiated by libations. Lesser shrines to Castor, Pollux and Helen were also established at a number of other locations around Sparta. The pear tree was regarded by the Spartans as sacred to Castor and Pollux, and images of the twins were hung in its