Schistosomiasis artesunate, or mefloquine. A Cochrane review found tentative evidence that when used alone, metrifonate was as effective as praziquantel. Another agent, mefloquine, which has previously been used to treat and prevent malaria, was recognised in 2008–2009 to be effective against "Schistosoma". Historically, antimony potassium tartrate remained the treatment of choice for schistosomiasis until the development of praziquantel in the 1980s. The disease is found in tropical countries in Africa, the Caribbean, eastern South America, Southeast Asia, and the Middle East. "S. mansoni" is found in parts of South America and the Caribbean, Africa, and the Middle East; "S. haematobium" in
Cute Is What We Aim For to finish up high school and after that I was like, 'Wow, I miss playing music.' I was blessed enough to get that opportunity again." However, Cimato left the band once again in March 2008. It was announced that Dave Melillo would play bass until further notice. In 2008, Cute Is What We Aim For entered the studio to record with producer John Feldmann. "Rotation" debuted at #21 on the U.S. Billboard 200 albums chart selling around 22,000 copies. In 2010, it was announced that the band Cute Is What We Aim For lost all of its members except for