Kype and/or characteristics that could be of importance in inter- and intra-sexual evaluations of individual quality. The size of the kype is believed to determine male spawning frequency. The extinct sabertooth salmon, "Oncorhynchus rastrosus", was first named for its prominent premaxillary dentition. It possesses an enormous conical tooth on each premaxilla. There is no visible kype on the dentary, implying a different strategy for forming mate dominance. Kype A kype is a hook-like secondary sex characteristic which develops at the distal tip of the lower jaw in some male salmonids prior to the spawning season. The structure usually develops in the
Osteonecrosis of the jaw 23–39 months and 42–46 months with high dose intravenous and oral bisphosphonates. A prospective, population based study by Mavrokokki "et al.". estimated an incidence of osteonecrosis of the jaw of 1.15% for intravenous bisphosphonates and 0.04% for oral bisphosphonates. Most cases (73%) were precipitated by dental extractions. In contrast, safety studies sponsored by the manufacturer reported bisphosphonate-associated osteonecrosis of the jaw rates that were much lower. Although the majority of cases of ONJ have occurred in cancer patients receiving high dose intravenous bisphosphonates, almost 800 cases have been reported in oral bisphosphonate users for osteoporosis or Pagets disease. In terms