Mefloquine one. Plasma concentrations of the (–)-enantiomer are significantly higher than those for the (+)-enantiomer, and the pharmacokinetics between the two enantiomers are significantly different. The (+)-enantiomer has a shorter half-life than the (–)-enantiomer. According to some research, the (+)-enantiomer is more effective in treating malaria, and the (–)-enantiomer specifically binds to adenosine receptors in the central nervous system, which may explain some of its psychotropic effects. Mefloquine was formulated at Walter Reed Army Institute of Research (WRAIR) in the 1970s shortly after the end of the Vietnam war. Mefloquine was number 142,490 of a total of 250,000 antimalarial compounds screened
Association for the Treatment of Sexual Abusers of sexual abuse through effective treatment and management of sex offenders. It has approximately 3,000 members from 26 countries, with chapters throughout the United States and in Utrecht, Netherlands. Members include researchers, treatment providers, corrections officials, attorneys, law enforcement officers, and students. ATSA hosts the world's largest annual conference and leading educational venue for individuals working on issues related to the research, treatment, and management of sexual abuse. Conference locations vary each year. The official journal of ATSA is "Sexual Abuse", produced eight times a year. According to the Institute for Scientific Information, the peer-reviewed journal's 2016 impact factor was