Mefloquine during the study. Mefloquine was the first Public-Private Venture (PPV) between the US Department of Defense and a pharmaceutical company. WRAIR transferred all its phase I and phase II clinical trial data to Hoffman LaRoche and Smith Kline. FDA approval as a treatment for malaria was swift. Most notably, phase III safety and tolerability trials were skipped. The drug was first approved and sold on a commercial basis in Switzerland in 1985. However, mefloquine was not approved by the FDA for prophylactic use until 1989. This approval was based primarily on compliance, while safety and tolerability were overlooked. Because of
What the World Needs Now Is Love "Hot Shots!", "Happy Gilmore", and "Forrest Gump". In the Danish zodiac porn comedy "I Jomfruens tegn" (1973), an extended version is used for the hardcore underwater orgy that ends the film. What the World Needs Now Is Love "What the World Needs Now Is Love" is a 1965 popular song with lyrics by Hal David and music composed by Burt Bacharach. First recorded and made popular by Jackie DeShannon, it was released on April 15, 1965, on the Imperial label after a release on sister label Liberty records the previous month was canceled. It peaked at number seven on the