PH a pH of 7.3. This is clearly wrong as an acid solution should have a pH of less than 7. Treating the system as a mixture of hydrochloric acid and the amphoteric substance water, a pH of 6.89 results. A weak acid or the conjugate acid of a weak base can be treated using the same formalism. First, an acid dissociation constant is defined as follows. Electrical charges are omitted from subsequent equations for the sake of generality and its value is assumed to have been determined by experiment. This being so, there are three unknown concentrations, [HA], [H] and
Gastric acid of the gastric gland and gradually reaches the main stomach lumen. The exact manner in which the secreted acid reaches the stomach lumen is controversial, as acid must first cross the relatively pH neutral gastric mucus layer. Chloride and sodium ions are secreted actively from the cytoplasm of the parietal cell into the lumen of the canaliculus. This creates a negative potential of -40 mV to -70 mV across the parietal cell membrane that causes potassium ions and a small number of sodium ions to diffuse from the cytoplasm into the parietal cell canaliculi. The enzyme carbonic anhydrase catalyses the