Mefloquine is not recommended for severe malaria infections, particularly infections from "P. falciparum", which should be treated with intravenous antimalarials. Mefloquine does not eliminate parasites in the liver phase of the disease, and people with "P. vivax" malaria should be treated with a second drug that is effective for the liver phase, such as primaquine. Mefloquine is widely used for the treatment of malaria in pregnancy. Limited data suggests that it is safe for this purpose. Resistance to mefloquine is now common around the west border in Cambodia and other parts of Southeast Asia. The mechanism of resistance is by increase
What Bird is That? author Nick Earls' 1999 young adult novel "48 Shades of Brown". The 48 shades refers to the number of distinct browns used by Cayley to describe bird plumage colours. What Bird is That? What Bird is That? A Guide to the Birds of Australia is a book first published in 1931 by Angus & Robertson in Sydney. Authored and illustrated by Neville William Cayley, it was Australia’s first fully illustrated national field guide to birds, a function it served alone for nearly 40 years. In 1960 it was rated the all-time best seller in Australian natural history. "What Bird Is