Half sphere exposure both HSEα and HSEβ based on a big dataset by using multiple-step iterative deep neural-network learning. The predicted HSEa shows a higher correlation coefficient to the stability change by residue mutants than predicted HSEβ and ASA. The results, together with its easy Ca-atom-based calculation, highlight the potential usefulness of predicted HSEa for protein structure prediction and refinement as well as function prediction. Half sphere exposure Half Sphere Exposure (HSE) is a protein solvent exposure measure that was first introduced by . Like all solvent exposure measures it measures how buried amino acid residues are in a protein. It is found
What Is This Thing Called Love? (short story) with aliens and sex. According to Asimov the article was mostly based on "Marvel" since its contents had been the raciest. Cele Goldsmith Lalli, editor of "Amazing Stories", requested a satire of the "Playboy" article. Asimov set out to write a story telling how a sex-interested alien and humans might "really" interact. The story appeared in the March 1961 issue of "Amazing" as "Playboy and the Slime God", but when Asimov included it in his 1969 collection "Nightfall and Other Stories" he retitled it "What Is This Thing Called Love?" Goldsmith Lalli rewrote the story's last three paragraphs, a change