Antimalarial medication multi-drug resistant "P. falciparum". It is a very potent blood schizonticide with a long half-life. It is thought to act by forming toxic heme complexes that damage parasitic food vacuoles. Mefloquine is effective in prophylaxis and for acute therapy. It is now used solely for the prevention of resistant strains of "P. falciparum" (usually combined with Artesunate) despite being effective against "P. vivax", "P. ovale" and "P. marlariae". Chloroquine/proguanil or sulfa drug-pyrimethamine combinations should be used in all other plasmodia infections. The major commercial manufacturer of mefloquine-based malaria treatment is Roche Pharmaceuticals, which markets the drug under the trade name
Fools Gold/What the World Is Waiting For and "What the World Is Waiting For" were recorded at Sawmills Studios in Cornwall during the late summer of 1989, with additional vocal and guitar parts recorded later at London's Battery Studios, during the autumn of 1989. The tracks had been worked on for four months, and the intention was to put "What the World Is Waiting For" as the A side; however, when Roddy Mckenna, Silvertone's A&R man, heard "Fools Gold" he urged the band to use that as the A-side. The band were not completely convinced, and it was agreed, instead, to release the two tracks as a