Half sphere exposure used in predicting discontinuous B-cell epitopes. Song et al. have developed an online webserver termed HSEpred to predict half-sphere exposure from protein primary sequences. HSEpred server can achieve the correlation coefficients of 0.72 and 0.68 between the predicted and observed HSE-up and HSE-down measures, respectively, when evaluated on a well-prepared non-homologous protein structure dataset. Moreover, residue contact number (CN) can also be accurately predicted by HSEpred webserver using the summation of the predicted HSE-up and HSE-down values, which has further enlarged the application of this new solvent exposure measure. Recently, Heffernan et al. has developed the most accurate predictor for
YIG sphere out of the sphere; the loops are half-turns, positioned at right-angles to each other to prevent direct electromagnetic coupling between them and each is grounded at one end. The field from an electromagnet changes the resonance frequency of the sphere and hence the frequency it will allow to pass. The advantage of this type of filter is that the garnet can be tuned over a very wide frequency range by varying the strength of the magnetic field. Some filters can be tuned from 3 GHz up to 50 GHz. YIG filters usually consist of several coupled stages, each stage consisting