Mefloquine one. Plasma concentrations of the (–)-enantiomer are significantly higher than those for the (+)-enantiomer, and the pharmacokinetics between the two enantiomers are significantly different. The (+)-enantiomer has a shorter half-life than the (–)-enantiomer. According to some research, the (+)-enantiomer is more effective in treating malaria, and the (–)-enantiomer specifically binds to adenosine receptors in the central nervous system, which may explain some of its psychotropic effects. Mefloquine was formulated at Walter Reed Army Institute of Research (WRAIR) in the 1970s shortly after the end of the Vietnam war. Mefloquine was number 142,490 of a total of 250,000 antimalarial compounds screened
Israel Center for the Treatment of Psychotrauma Israel Center for the Treatment of Psychotrauma The Israel Center for the Treatment of Psychotrauma (ICTP) affiliated with Herzog Hospital in Jerusalem, Israel, is a community-based trauma center The Israel Center for the Treatment of Psychotrauma was established in 1989 to improve the level of trauma-related services in Israel and around the world. ICTP has developed a comprehensive range of clinical and community-based services. ICTP is today involved in the research and treatment of the widespread effects of trauma caused by terrorism, war and natural disaster. ICTP has been active in its present form since 1989, but draws on a