Schistosomiasis artesunate, or mefloquine. A Cochrane review found tentative evidence that when used alone, metrifonate was as effective as praziquantel. Another agent, mefloquine, which has previously been used to treat and prevent malaria, was recognised in 2008–2009 to be effective against "Schistosoma". Historically, antimony potassium tartrate remained the treatment of choice for schistosomiasis until the development of praziquantel in the 1980s. The disease is found in tropical countries in Africa, the Caribbean, eastern South America, Southeast Asia, and the Middle East. "S. mansoni" is found in parts of South America and the Caribbean, Africa, and the Middle East; "S. haematobium" in
People for the Ethical Treatment of Animals used for live transport and traditional religious slaughter. The organization has also used the PETA Lettuce Ladies in local demonstrations. PETA Asia-Pacific regularly demonstrates against KFC outlets to promote better treatment of chickens used by the company. PETA Asia-Pacific supports the PETA campaign "I'd Rather Go Naked Than Wear Fur," in which celebrities appear nude to express their opposition to wearing fur. The group also stages anti-fur events to publicize its opposition to fur. PETA Asia-Pacific has been involved in several undercover investigations of fur farms in China. The group regularly protests the use of animals in entertainment, including circuses.