Mefloquine the drug's very long half-life, the Centers for Disease Control originally recommended a mefloquine dosage of 250 mg every two weeks; however, this caused an unacceptably high malaria rate in the Peace Corps volunteers who participated in the approval study, so the drug regimen was switched to once a week. The first randomized, controlled trial on a mixed population was performed in 2001. Prophylaxis with mefloquine was compared to prophylaxis with atovaquone-proguanil. Roughly 67% of participants in the mefloquine arm reported greater than or equal to one adverse event, vs 71% in the atovaquone-proguanil arm. In the mefloquine arm, 5%
What is this Feeling? and new?/I felt the moment I laid eyes on you/My pulse is rushing/My head is reeling/My face is flushing/What is this feeling?/Fervid as a flame/Does it have a name?"). The irony comes in when phrases traditionally used for love songs are revealed to be expressing hate. When Galinda and Elphaba describe each other, Galinda complains about Elphaba being "utterly impossible to describe", while Elphaba simply calls Galinda "blonde". At the end of the song, Elphaba scares Galinda, by saying "Boo", with Galinda letting out a high-pitched squeal. What is this Feeling? "What is this Feeling?" is a song from the