Drug injection taking drugs, injection is favoured by some people as the full effects of the drug are experienced very quickly, typically in five to ten seconds. It also bypasses first-pass metabolism in the liver, resulting in higher bioavailability and efficiency for many drugs (such as morphine or diacetylmorphine/heroin; roughly two-thirds of which is destroyed in the liver when consumed orally) than oral ingestion would. The effect is that the person gets a stronger (yet shorter-acting) effect from the same amount of the drug. Drug injection is therefore often related to substance dependence. In a recreational context, the shorter, more intense "high"
Drug harmfulness Drug harmfulness Drug harmfulness is the degree to which a psychoactive drug is harmful to a user and is measured in various ways, such as by addictiveness and the potential for physical harm. More harmful drugs are called "hard drugs" and less harmful drugs are called "soft drugs". The term "soft drug" is considered controversial by its critics as it may imply that soft drugs cause no or insignificant harm. The distinction between soft drugs and hard drugs is important in the drug policy of the Netherlands, where cannabis production, retail and use come under official tolerance, subject to certain