Mefloquine one. Plasma concentrations of the (–)-enantiomer are significantly higher than those for the (+)-enantiomer, and the pharmacokinetics between the two enantiomers are significantly different. The (+)-enantiomer has a shorter half-life than the (–)-enantiomer. According to some research, the (+)-enantiomer is more effective in treating malaria, and the (–)-enantiomer specifically binds to adenosine receptors in the central nervous system, which may explain some of its psychotropic effects. Mefloquine was formulated at Walter Reed Army Institute of Research (WRAIR) in the 1970s shortly after the end of the Vietnam war. Mefloquine was number 142,490 of a total of 250,000 antimalarial compounds screened
What the World Needs Now Is Love assassination, and Martin Luther King, Jr., and soundbites of news coverage of each assassination. The ending of the song is a reprise of the introduction. "What the World Needs Now is Love/Abraham, Martin and John" rose to No. 8 on the "Billboard" Hot 100 in August 1971, and was Clay's only Top 40 hit. "What the World Needs Now is Love" has been used in many film soundtracks, notably "Bob & Carol & Ted & Alice" and "For the Love of Fred" (used as the film's closing theme song in both), "", "My Best Friend's Wedding", "", "The Boss Baby",