Half sphere exposure both HSEα and HSEβ based on a big dataset by using multiple-step iterative deep neural-network learning. The predicted HSEa shows a higher correlation coefficient to the stability change by residue mutants than predicted HSEβ and ASA. The results, together with its easy Ca-atom-based calculation, highlight the potential usefulness of predicted HSEa for protein structure prediction and refinement as well as function prediction. Half sphere exposure Half Sphere Exposure (HSE) is a protein solvent exposure measure that was first introduced by . Like all solvent exposure measures it measures how buried amino acid residues are in a protein. It is found
Celestial sphere spheres" was thought to carry the fixed stars. Eudoxus used 27 concentric spherical solids to answer Plato's challenge: "By the assumption of what uniform and orderly motions can the apparent motions of the planets be accounted for?" A celestial sphere can also refer to a physical model of the celestial sphere or celestial globe. Such globes map the constellations on the "outside" of a sphere, resulting in a mirror image of the constellations as seen from Earth. The oldest surviving example of such an artifact is the globe of the Farnese Atlas sculpture, a 2nd-century copy of an older (Hellenistic