Half sphere exposure both HSEα and HSEβ based on a big dataset by using multiple-step iterative deep neural-network learning. The predicted HSEa shows a higher correlation coefficient to the stability change by residue mutants than predicted HSEβ and ASA. The results, together with its easy Ca-atom-based calculation, highlight the potential usefulness of predicted HSEa for protein structure prediction and refinement as well as function prediction. Half sphere exposure Half Sphere Exposure (HSE) is a protein solvent exposure measure that was first introduced by . Like all solvent exposure measures it measures how buried amino acid residues are in a protein. It is found
Mutha Is Half a Word Blind Woman" and "Smell the Sardines", bits she performed on TV later in her career. She also parodies the hit "Winchester Cathedral" in which she explains that a man working at a funeral parlor discovered a cork in a man's butt, taking the cork out only to hear the butt singing the song. The title of the book "Mutha Is Half a Word: Intersections of Folklore, Vernacular, Myth, and Queerness in Black Female Culture (Black Performance and Cultural Criticism)" is a reference to this album as it stands as a stereotype of modern black female humor. Mutha Is Half a