Half sphere exposure Half sphere exposure Half Sphere Exposure (HSE) is a protein solvent exposure measure that was first introduced by . Like all solvent exposure measures it measures how buried amino acid residues are in a protein. It is found by counting the number of amino acid neighbors within two half spheres of chosen radius around the amino acid. The calculation of HSE is found by dividing a contact number (CN) sphere in two halves by the plane perpendicular to the Cβ-Cα vector. This simple division of the CN sphere results in two strikingly different measures, HSE-up and HSE-down. HSE-up is defined
Sphere (website) Sphere (website) Sphere was a blog search engine. The Sphere search engine delivered blog posts based on algorithms that combine semantic matching with authority factors to deliver results relevant to the search query. Sphere also organized bloggers by topic. The company produced an application called Sphere It! allowing users to seek blog posts related to news articles based on the contents of a particular web page they're viewing. The function was accessed from a browser navigation bar plug-in. Upon clicking the plug-in button, a semantic analysis was performed on the text within the page and blog posts related to the