Half sphere exposure Half sphere exposure Half Sphere Exposure (HSE) is a protein solvent exposure measure that was first introduced by . Like all solvent exposure measures it measures how buried amino acid residues are in a protein. It is found by counting the number of amino acid neighbors within two half spheres of chosen radius around the amino acid. The calculation of HSE is found by dividing a contact number (CN) sphere in two halves by the plane perpendicular to the Cβ-Cα vector. This simple division of the CN sphere results in two strikingly different measures, HSE-up and HSE-down. HSE-up is defined
Bernal sphere optimum mass-efficiency at providing radiation shielding. O'Neill envisioned the next generation of space habitat as a larger version of "Island One". "Island Two" would be approximately 1800 meters in diameter, yielding an equatorial circumference of nearly six and a half kilometers (four miles). The size was driven by economics; the habitat was to be small enough to allow for efficient transportation within the habitat and large enough to support an efficient industrial base. Bernal sphere A Bernal sphere is a type of space habitat intended as a long-term home for permanent residents, first proposed in 1929 by John Desmond Bernal.