Acetophenone is also a component of castoreum, the exudate from the castor sacs of the mature beaver. In the late 19th and early 20th centuries, acetophenone was used in medicine. It was marketed as a hypnotic and anticonvulsant under brand name Hypnone. The typical dosage was 0.12 to 0.3 milliliters. It was considered to have superior sedative effects to both paraldehyde and chloral hydrate. In humans, acetophenone is metabolized to benzoic acid, carbonic acid, and acetone. Hippuric acid occurs as an indirect metabolite and its quantity in urine may be used to confirm acetophenone exposure, although other substances, like toluene, also
Castor and Pollux Castor (Alpha Geminorum) and Pollux (Beta Geminorum). As emblems of immortality and death, the Dioscuri, like Heracles, were said to have been initiated into the Eleusinian mysteries. Castor and Pollux are consistently associated with horses in art and literature. They are widely depicted as helmeted horsemen carrying spears. The Pseudo-Oppian manuscript depicts the brothers hunting, both on horseback and on foot. On votive reliefs they are depicted with a variety of symbols representing the concept of twinhood, such as the "dokana" (δόκανα – two upright pieces of wood connected by two cross-beams), a pair of amphorae, a pair of shields,