Half sphere exposure both HSEα and HSEβ based on a big dataset by using multiple-step iterative deep neural-network learning. The predicted HSEa shows a higher correlation coefficient to the stability change by residue mutants than predicted HSEβ and ASA. The results, together with its easy Ca-atom-based calculation, highlight the potential usefulness of predicted HSEa for protein structure prediction and refinement as well as function prediction. Half sphere exposure Half Sphere Exposure (HSE) is a protein solvent exposure measure that was first introduced by . Like all solvent exposure measures it measures how buried amino acid residues are in a protein. It is found
What Is a Man Without a Moustache? Times" had also expressed opinions of a divided nature. He called the film "pleasant if inconsequential", offered an opinion that it contains "good-natured sensibility" and a "slightly fabulous tone" while still feeling like "magic realism, without the magic", and concluded his review by stating that "the pleasant pointless of it all is laced with a tantalizing tease of allegory suggested by the dialectical twins and the strain of mellow nationalism in the dialogue." Reviewing the film for "TV Guide", Maitland McDonagh awarded the film three stars out of four calling it "sardonic" and "absurdist". What Is a Man Without a