Half sphere exposure used in predicting discontinuous B-cell epitopes. Song et al. have developed an online webserver termed HSEpred to predict half-sphere exposure from protein primary sequences. HSEpred server can achieve the correlation coefficients of 0.72 and 0.68 between the predicted and observed HSE-up and HSE-down measures, respectively, when evaluated on a well-prepared non-homologous protein structure dataset. Moreover, residue contact number (CN) can also be accurately predicted by HSEpred webserver using the summation of the predicted HSE-up and HSE-down values, which has further enlarged the application of this new solvent exposure measure. Recently, Heffernan et al. has developed the most accurate predictor for
Celestial Sphere Woodrow Wilson Memorial Celestial Sphere Woodrow Wilson Memorial The grounds of the Palais des Nations (seat of the United Nations Office at Geneva) contain many fine objects donated by member states of the United Nations, private sponsors and artists. The Celestial Sphere (also known as the Armillary Sphere) in the Ariana Park of the Palais des Nations is the best-known of these. The huge - over four meter diameter - "Celestial Sphere" is the chef d'oeuvre of the American sculptor Paul Manship (1885–1966). It was donated in 1939 by the Woodrow Wilson Foundation to what was then the League of Nations building. Known