Mefloquine drug composed of only the (+)-enantiomer. Mefloquine alters cholinergic synaptic transmission through both postsynaptic and presynaptic actions. The postsynaptic action to inhibit acetylcholinesterase changes transmission across synapses in the brain. Mefloquine Mefloquine, sold under the brand names Lariam among others, is a medication used to prevent or treat malaria. When used for prevention it is taken once a week and should be started one or two weeks before potential exposure and continued for four weeks after potential exposure. It can be used to treat mild or moderate malaria but should not be used to treat severe malaria. It is taken
The World Is What It Is The World Is What It Is The World Is What It Is: The Authorized Biography of V. S. Naipaul is a biography of the Nobel Prize-winning author V. S. Naipaul by Patrick French. It was published in 2008 (by Picador in the UK and Knopf in the USA). The title is a quotation from Naipaul's book "A Bend in the River". "The world is what it is; men who are nothing, who allow themselves to become nothing, have no place in it." French deals with Naipaul's family background and his life from his birth in 1932 until his second marriage