Antimalarial medication multi-drug resistant "P. falciparum". It is a very potent blood schizonticide with a long half-life. It is thought to act by forming toxic heme complexes that damage parasitic food vacuoles. Mefloquine is effective in prophylaxis and for acute therapy. It is now used solely for the prevention of resistant strains of "P. falciparum" (usually combined with Artesunate) despite being effective against "P. vivax", "P. ovale" and "P. marlariae". Chloroquine/proguanil or sulfa drug-pyrimethamine combinations should be used in all other plasmodia infections. The major commercial manufacturer of mefloquine-based malaria treatment is Roche Pharmaceuticals, which markets the drug under the trade name
What the World Needs Now Is Love assassination, and Martin Luther King, Jr., and soundbites of news coverage of each assassination. The ending of the song is a reprise of the introduction. "What the World Needs Now is Love/Abraham, Martin and John" rose to No. 8 on the "Billboard" Hot 100 in August 1971, and was Clay's only Top 40 hit. "What the World Needs Now is Love" has been used in many film soundtracks, notably "Bob & Carol & Ted & Alice" and "For the Love of Fred" (used as the film's closing theme song in both), "", "My Best Friend's Wedding", "", "The Boss Baby",