Mefloquine the drug's very long half-life, the Centers for Disease Control originally recommended a mefloquine dosage of 250 mg every two weeks; however, this caused an unacceptably high malaria rate in the Peace Corps volunteers who participated in the approval study, so the drug regimen was switched to once a week. The first randomized, controlled trial on a mixed population was performed in 2001. Prophylaxis with mefloquine was compared to prophylaxis with atovaquone-proguanil. Roughly 67% of participants in the mefloquine arm reported greater than or equal to one adverse event, vs 71% in the atovaquone-proguanil arm. In the mefloquine arm, 5%
This Is What the Edge of Your Seat Was Made For You're Dead? Nobody.", "Dagger", "Passe Compose", "Traitors Never Play Hangman" and "We Are All Movie Stars". The artwork was different as well, with the cover featuring the band's logo with a sparrow in the corner of the cover standing about a bottle of leaking love hearts. Jack Rogers writing for "Rock Sound" reviewed the song "RE: They Have No Reflections" and commented that it is "Scrappy, heavy and completely and utterly debauched". This Is What the Edge of Your Seat Was Made For This Is What the Edge of Your Seat Was Made For is the first release by Bring