Half sphere exposure used in predicting discontinuous B-cell epitopes. Song et al. have developed an online webserver termed HSEpred to predict half-sphere exposure from protein primary sequences. HSEpred server can achieve the correlation coefficients of 0.72 and 0.68 between the predicted and observed HSE-up and HSE-down measures, respectively, when evaluated on a well-prepared non-homologous protein structure dataset. Moreover, residue contact number (CN) can also be accurately predicted by HSEpred webserver using the summation of the predicted HSE-up and HSE-down values, which has further enlarged the application of this new solvent exposure measure. Recently, Heffernan et al. has developed the most accurate predictor for
MSG Sphere London have high speed internet access. The sound system will deliver sound through the floorboards. The exterior of the venue will feature a 360 degree IMAX display which will allow those who are outside of the venue to see what is going on inside. The MSG Sphere will be accessible through a variety of mass transit links, including rail and bus. The MSG Sphere London will be accessible via the London Underground's Central line and Jubilee line at the Stratford station. Spectators will also be able to access the MSG Sphere via Docklands Light Railway at Stratford station and Stratford International