Antimalarial medication multi-drug resistant "P. falciparum". It is a very potent blood schizonticide with a long half-life. It is thought to act by forming toxic heme complexes that damage parasitic food vacuoles. Mefloquine is effective in prophylaxis and for acute therapy. It is now used solely for the prevention of resistant strains of "P. falciparum" (usually combined with Artesunate) despite being effective against "P. vivax", "P. ovale" and "P. marlariae". Chloroquine/proguanil or sulfa drug-pyrimethamine combinations should be used in all other plasmodia infections. The major commercial manufacturer of mefloquine-based malaria treatment is Roche Pharmaceuticals, which markets the drug under the trade name
People for the Ethical Treatment of Animals used for live transport and traditional religious slaughter. The organization has also used the PETA Lettuce Ladies in local demonstrations. PETA Asia-Pacific regularly demonstrates against KFC outlets to promote better treatment of chickens used by the company. PETA Asia-Pacific supports the PETA campaign "I'd Rather Go Naked Than Wear Fur," in which celebrities appear nude to express their opposition to wearing fur. The group also stages anti-fur events to publicize its opposition to fur. PETA Asia-Pacific has been involved in several undercover investigations of fur farms in China. The group regularly protests the use of animals in entertainment, including circuses.