Half sphere exposure Half sphere exposure Half Sphere Exposure (HSE) is a protein solvent exposure measure that was first introduced by . Like all solvent exposure measures it measures how buried amino acid residues are in a protein. It is found by counting the number of amino acid neighbors within two half spheres of chosen radius around the amino acid. The calculation of HSE is found by dividing a contact number (CN) sphere in two halves by the plane perpendicular to the Cβ-Cα vector. This simple division of the CN sphere results in two strikingly different measures, HSE-up and HSE-down. HSE-up is defined
Mutha Is Half a Word Blind Woman" and "Smell the Sardines", bits she performed on TV later in her career. She also parodies the hit "Winchester Cathedral" in which she explains that a man working at a funeral parlor discovered a cork in a man's butt, taking the cork out only to hear the butt singing the song. The title of the book "Mutha Is Half a Word: Intersections of Folklore, Vernacular, Myth, and Queerness in Black Female Culture (Black Performance and Cultural Criticism)" is a reference to this album as it stands as a stereotype of modern black female humor. Mutha Is Half a