Mefloquine the drug's very long half-life, the Centers for Disease Control originally recommended a mefloquine dosage of 250 mg every two weeks; however, this caused an unacceptably high malaria rate in the Peace Corps volunteers who participated in the approval study, so the drug regimen was switched to once a week. The first randomized, controlled trial on a mixed population was performed in 2001. Prophylaxis with mefloquine was compared to prophylaxis with atovaquone-proguanil. Roughly 67% of participants in the mefloquine arm reported greater than or equal to one adverse event, vs 71% in the atovaquone-proguanil arm. In the mefloquine arm, 5%
International Association for the Treatment of Sexual Offenders changes as well. A "one size fits all" approach can not be used because youth who have committed sexual crimes are a diverse population, meaning they are all different in numerous ways. Treatment response to sexual abuse by juveniles is based on relapsed prevention, offense cycle, and presumption of sexual dividends. Some research coming out suggests that the successful treatments are those which include community-based and involve supportive adults in the youth's life. Something to keep in mind is label the behavior of the youth, not their identity, because it helps to make sure that youths do not develop a