Artesunate suppositories work with artemisinin suppositories in severe malaria was conducted in Viet Nam in the early 1990s, and clinical trials of rectal artesunate followed by mefloquine treatment in moderately severe malaria were conducted in the mid-1990s in Thailand. A major placebo-controlled clinical trial published in 2009 found that "if patients with severe malaria cannot be treated orally and access to injections will take several hours, a single inexpensive artesunate [rectal] suppository at the time of referral substantially reduces the risk of death or permanent disability." Artesunate suppositories Artesunate suppositories are used for the treatment of malaria. Artesunate is an antimalarial water-soluble
This Is What You Came For among artists to 73). "This Is What You Came For" became Rihanna's 25th and Harris's fourth number one on the Hot Dance Club Songs Chart, where it became the first song since 2013's "Wake Me Up" to stay at number one for two weeks. As of October 2016, the single has sold 1.2 million copies in the United States. "This Is What You Came For" debuted at number one on the Scottish Singles Chart, and peaked at number one in Australia, Canada and Ireland. The song also reached the top 10 in Germany, Ireland, New Zealand, Switzerland, Belgium, Denmark, Finland,