Half sphere exposure Half sphere exposure Half Sphere Exposure (HSE) is a protein solvent exposure measure that was first introduced by . Like all solvent exposure measures it measures how buried amino acid residues are in a protein. It is found by counting the number of amino acid neighbors within two half spheres of chosen radius around the amino acid. The calculation of HSE is found by dividing a contact number (CN) sphere in two halves by the plane perpendicular to the Cβ-Cα vector. This simple division of the CN sphere results in two strikingly different measures, HSE-up and HSE-down. HSE-up is defined
The Sphere (social network) manage their private, social and business lives such as private mailbox, Online chat, photo and video albums, geolocation, city guide. The-Sphere's network offers its members an online magazine. The-Sphere's magazine is called “Trends&Events”. Upon joining, members can learn about that and other of The Sphere's products and services. The-Sphere provides its member a concierge service. The Sphere provides its members an international address book. The-Sphere encourages off-line interactions between members. Recent Events include “Par Coeur Gala” to benefit the Make-A-Wish Foundation France association and hosted by The-Sphere ambassador Eva Longoria. The Sphere (social network) The-Sphere.com is a social network service.