Mefloquine is not recommended for severe malaria infections, particularly infections from "P. falciparum", which should be treated with intravenous antimalarials. Mefloquine does not eliminate parasites in the liver phase of the disease, and people with "P. vivax" malaria should be treated with a second drug that is effective for the liver phase, such as primaquine. Mefloquine is widely used for the treatment of malaria in pregnancy. Limited data suggests that it is safe for this purpose. Resistance to mefloquine is now common around the west border in Cambodia and other parts of Southeast Asia. The mechanism of resistance is by increase
Murder Ain't What it Used to Be move a vase by telekinesis and can manipulate objects, such as a cigar, a machine gun and a hat. It also appears that he is connected psychically with Jeannie when he hears her scream in her apartment. Also for the first time since the debut episode, the effect of ghosts on the room atmosphere is commented on, with Paul Kirstner's sister Aunt Maddox complaining "it has turned cold" when Bugsy appears. Murder Ain't What it Used to Be Murder Ain't What it Used to Be is the seventh episode of the popular 1969 ITC British television series "Randall and Hopkirk