Mefloquine during the study. Mefloquine was the first Public-Private Venture (PPV) between the US Department of Defense and a pharmaceutical company. WRAIR transferred all its phase I and phase II clinical trial data to Hoffman LaRoche and Smith Kline. FDA approval as a treatment for malaria was swift. Most notably, phase III safety and tolerability trials were skipped. The drug was first approved and sold on a commercial basis in Switzerland in 1985. However, mefloquine was not approved by the FDA for prophylactic use until 1989. This approval was based primarily on compliance, while safety and tolerability were overlooked. Because of
This Is What the Edge of Your Seat Was Made For You're Dead? Nobody.", "Dagger", "Passe Compose", "Traitors Never Play Hangman" and "We Are All Movie Stars". The artwork was different as well, with the cover featuring the band's logo with a sparrow in the corner of the cover standing about a bottle of leaking love hearts. Jack Rogers writing for "Rock Sound" reviewed the song "RE: They Have No Reflections" and commented that it is "Scrappy, heavy and completely and utterly debauched". This Is What the Edge of Your Seat Was Made For This Is What the Edge of Your Seat Was Made For is the first release by Bring