Lake pigment rich red color. They were very often used by Titian and other Venetian artists of the 16th century to depict fine draperies and fabrics. Indigo and rose madder are now produced more cheaply from synthetic sources, although some use of natural products persists, especially among artisans. The food and cosmetics industries have shown renewed interest in cochineal as a source of natural red dye. Lake pigment A lake pigment is a pigment made by precipitating a dye with an inert binder, or "mordant", usually a metallic salt. Unlike vermilion, ultramarine, and other pigments made from ground minerals, lake pigments are
Labrador Retriever coat colour genetics the colour of the dark pigment, eumelanin, and is referred to as the B (brown) locus. The variation displayed by this locus is observed in many mammals, reflecting a so-called 'dilution', a lightening, of black eumelanin to a brown colour. Initial genetic research excluded a role for the melanocortin 1 receptor and the "Agouti" locus as being the cause of the black dilution trait in dogs. Instead, TYRP1 (tyrosine related protein 1) was found to be responsible. This enzyme is localised to melanosomes, the cellular organelles that produce and store pigments, and serves to catalyze oxidation of eumelanin precursors. In