Drug injection can lead to a dependency by both physical and psychological means — and develops more quickly than with other methods of taking drugs. In recreational-use drug culture, preparation may include mixing the powdered drug with water to create an aqueous solution, and then the solution is injected. This act is often colloquially referred to as "slamming", "shooting [up]", “smashing”, "banging", "pinning", or "jacking-up", often depending on the specific drug subculture in which the term is used (i.e. heroin, cocaine, or methamphetamine). There are a variety of reasons why drugs would be more attractive to inject rather than take through other
Drug Price Competition and Patent Term Restoration Act the Act allowed the life of patents covering a drug to be extended by a portion of the time the drug is under regulatory review by the FDA, ensuring innovator companies that regulatory review will not unduly consume patent life. The Act also requires the drug innovator to provide the FDA with the numbers of patents it believes cover its drug; the FDA does not evaluate whether the patents cover the drug or not, but it publicly lists those patents in the Orange Book, and these are the patents, the life of which gets extended if there are regulatory delays.