Acetophenone is also a component of castoreum, the exudate from the castor sacs of the mature beaver. In the late 19th and early 20th centuries, acetophenone was used in medicine. It was marketed as a hypnotic and anticonvulsant under brand name Hypnone. The typical dosage was 0.12 to 0.3 milliliters. It was considered to have superior sedative effects to both paraldehyde and chloral hydrate. In humans, acetophenone is metabolized to benzoic acid, carbonic acid, and acetone. Hippuric acid occurs as an indirect metabolite and its quantity in urine may be used to confirm acetophenone exposure, although other substances, like toluene, also
Oily to Bed, Oily to Rise Oily to Bed, Oily to Rise Oily to Bed, Oily to Rise is the 42nd short film released by Columbia Pictures in 1939 starring American slapstick comedy team The Three Stooges (Moe Howard, Larry Fine and Curly Howard). The comedians released 190 short films for the studio between 1934 and 1959. The Stooges are three hapless tramps. After nearly destroying a farmer's (Richard Fiske) pile of firewood, and destroying some of his equipment, they hit the road. Curly wishes they had a car after they stop for a break. By accident they think they've found a car for free and