Mefloquine is not recommended for severe malaria infections, particularly infections from "P. falciparum", which should be treated with intravenous antimalarials. Mefloquine does not eliminate parasites in the liver phase of the disease, and people with "P. vivax" malaria should be treated with a second drug that is effective for the liver phase, such as primaquine. Mefloquine is widely used for the treatment of malaria in pregnancy. Limited data suggests that it is safe for this purpose. Resistance to mefloquine is now common around the west border in Cambodia and other parts of Southeast Asia. The mechanism of resistance is by increase
Fools Gold/What the World Is Waiting For and "What the World Is Waiting For" were recorded at Sawmills Studios in Cornwall during the late summer of 1989, with additional vocal and guitar parts recorded later at London's Battery Studios, during the autumn of 1989. The tracks had been worked on for four months, and the intention was to put "What the World Is Waiting For" as the A side; however, when Roddy Mckenna, Silvertone's A&R man, heard "Fools Gold" he urged the band to use that as the A-side. The band were not completely convinced, and it was agreed, instead, to release the two tracks as a