Antimalarial medication multi-drug resistant "P. falciparum". It is a very potent blood schizonticide with a long half-life. It is thought to act by forming toxic heme complexes that damage parasitic food vacuoles. Mefloquine is effective in prophylaxis and for acute therapy. It is now used solely for the prevention of resistant strains of "P. falciparum" (usually combined with Artesunate) despite being effective against "P. vivax", "P. ovale" and "P. marlariae". Chloroquine/proguanil or sulfa drug-pyrimethamine combinations should be used in all other plasmodia infections. The major commercial manufacturer of mefloquine-based malaria treatment is Roche Pharmaceuticals, which markets the drug under the trade name
Cute Is What We Aim For to finish up high school and after that I was like, 'Wow, I miss playing music.' I was blessed enough to get that opportunity again." However, Cimato left the band once again in March 2008. It was announced that Dave Melillo would play bass until further notice. In 2008, Cute Is What We Aim For entered the studio to record with producer John Feldmann. "Rotation" debuted at #21 on the U.S. Billboard 200 albums chart selling around 22,000 copies. In 2010, it was announced that the band Cute Is What We Aim For lost all of its members except for