History of aspirin History of aspirin The history of aspirin (IUPAC name acetylsalicylic acid ) begins with its synthesis and manufacture in 1899. Before that, salicylic acid had been used medicinally since antiquity. Medicines made from willow and other salicylate-rich plants appear in clay tablets from ancient Sumer as well as the Ebers Papyrus from ancient Egypt. Hippocrates referred to their use of salicylic tea to reduce fevers around 400 BC, and were part of the pharmacopoeia of Western medicine in classical antiquity and the Middle Ages. Willow bark extract became recognized for its specific effects on fever, pain and inflammation in the
The Indian in the Cupboard the French, and Boone wishes that he could somehow supply his friend with the "modern" six-shooters that are common in Boone's late 19th century timeline. Patrick gets the idea to take plastic soldiers (with 20th century weaponry) back through the cupboard to Little Bear's time. Little Bear likes the idea of modern weapons, but refuses to bring English soldiers back to his village. Omri is reluctant, believing this amounts to meddling with history, but is won over by his desire to save Little Bear's people. The boys buy several more plastic Iroquois figures from the local shops and bring them