Polio vaccine attenuated vaccine strains. In 1958, the National Institutes of Health created a special committee on live polio vaccines. The various vaccines were carefully evaluated for their ability to induce immunity to polio, while retaining a low incidence of neuropathogenicity in monkeys. Large-scale clinical trials performed in the Soviet Union in late 1950s to early 1960s by Mikhail Chumakov and his colleagues demonstrated safety and high efficacy of the vaccine. Based on these results, the Sabin strains were chosen for worldwide distribution. Fifty-seven nucleotide substitutions distinguish the attenuated Sabin 1 strain from its virulent parent (the Mahoney serotype), two nucleotide substitutions
His Name Is Alive His Name Is Alive His Name Is Alive is an American experimental rock band/project from Livonia, Michigan, United States. After several self-released cassettes, they debuted on 4AD Records in 1990, starting a long run at the label. Throughout the band's long history, leader Warren Defever has been the only constant member, with a variety of musicians and singers contributing over the years. Defever began recording in his basement in 1985, while still in high school. His initial work consisted primarily of Defever alone recording the music to a 4-track recorder, with friend Angie Carozzo providing vocals. After Defever went off