Acetyl group known as paracetamol), and acetylsalicylic acid (better known as aspirin). The introduction of an acetyl group into a molecule is called acetylation. In biological organisms, acetyl groups are commonly transferred from acetyl-CoA to other organic molecules. Acetyl-CoA is an intermediate both in the biological synthesis and in the breakdown of many organic molecules. Acetyl-CoA is also created during the second stage of cellular respiration, the Krebs Cycle, by the action of pyruvate dehydrogenase on pyruvic acid. Histones and other proteins are often modified by acetylation. For example, on the DNA level, histone acetylation by acetyltransferases (HATs) causes an expansion of
The Indian in the Cupboard the nurse in the cupboard and bring her to life. The nurse, called Matron, believing she has has dozed off while on duty, saves Little Bear's life. Matron also announces that Bright Stars is pregnant and the boys decide that it would be safer to keep Bright Stars with them until after the baby is born, rather than return her to her war-torn village. Patrick brings the cowboy Boone back to life through the cupboard in order to help Bright Stars care for Little Bear. Little Bear tells Boone about the troubles his people are suffering during their war with