Polio vaccine polio and post-polio syndrome. In the United States, vaccine is administered along with the tetanus, diphtheria, and acellular pertussis vaccines (DTaP) and a pediatric dose of hepatitis B vaccine. In the UK, IPV is combined with tetanus, diphtheria, pertussis, and "Haemophilus influenzae" type b vaccines. OPV is an attenuated vaccine, produced by the passage of the virus through nonhuman cells at a subphysiological temperature, which produces spontaneous mutations in the viral genome. Oral polio vaccines were developed by several groups, one of which was led by Albert Sabin. Other groups, led by Hilary Koprowski and H.R. Cox, developed their own
David Bruce (microbiologist) tsetse fly vector, of African trypanosomiasis ("sleeping sickness"). He was Surgeon-General for the duration of the First World War from 1914–19 at the Royal Army Medical College, Millbank, London. "Brucella" is the genus and Brucellaceae is the family of the bacteria which was named after him, in recognition of his discoveries. "Brucella melitensis" is the cause of undulant fever in man and of abortion in goats. It is usually transmitted by goat's milk. "Trypanosoma brucei", the cause of sleeping sickness, is also named after him. Bruce was elected a Fellow of the Royal Society (FRS) in 1899. He served as