Acetyl group known as paracetamol), and acetylsalicylic acid (better known as aspirin). The introduction of an acetyl group into a molecule is called acetylation. In biological organisms, acetyl groups are commonly transferred from acetyl-CoA to other organic molecules. Acetyl-CoA is an intermediate both in the biological synthesis and in the breakdown of many organic molecules. Acetyl-CoA is also created during the second stage of cellular respiration, the Krebs Cycle, by the action of pyruvate dehydrogenase on pyruvic acid. Histones and other proteins are often modified by acetylation. For example, on the DNA level, histone acetylation by acetyltransferases (HATs) causes an expansion of
The Indian in the Cupboard but does not know enough medicine to save Boone, while the boys are far too large to help. Omri brings to life the figure of a World War I medic, who turns out to be a man named Tommy from the trenches of France. Tommy, believing that this is a strange dream, saves Boone's life before being transported back through the cupboard. Little Bear continues to treat Boone's injuries and the two gradually come to trust one another. This incident finally impresses upon Patrick that the tiny people are not toys. Though both boys have become attached to Boone and