Aspirin for its health effects for at least 2,400 years. In 1853, chemist Charles Frédéric Gerhardt treated the medicine sodium salicylate with acetyl chloride to produce acetylsalicylic acid for the first time. For the next fifty years, other chemists established the chemical structure and came up with more efficient methods to make it. In 1897, scientists at the Bayer company began studying acetylsalicylic acid as a less-irritating replacement medication for common salicylate medicines. By 1899, Bayer had named it "Aspirin" and sold it around the world. Aspirin's popularity grew over the first half of the twentieth century leading to competition between
The Indian in the Cupboard meets Tom's daughter, who is wearing the long-lost earrings. Omri realizes that Jessica gave the earrings to Tom, who gave them to his daughter without knowing they were stolen. Having solved the mystery, he decides not to tell Tom's daughter the story of the earrings. Omri returns home to find that his father, while rebuilding Omri's bedroom, found the key, the cupboard, and the plastic figure of Little Bear and locked the toy in the cupboard, where he was shocked when Little Bear came to life. He has since been too frightened to open the cupboard while Little Bear called