Acetyl group known as paracetamol), and acetylsalicylic acid (better known as aspirin). The introduction of an acetyl group into a molecule is called acetylation. In biological organisms, acetyl groups are commonly transferred from acetyl-CoA to other organic molecules. Acetyl-CoA is an intermediate both in the biological synthesis and in the breakdown of many organic molecules. Acetyl-CoA is also created during the second stage of cellular respiration, the Krebs Cycle, by the action of pyruvate dehydrogenase on pyruvic acid. Histones and other proteins are often modified by acetylation. For example, on the DNA level, histone acetylation by acetyltransferases (HATs) causes an expansion of
The Full Cupboard of Life series in America. "This novel by an eminent Scottish law professor about a woman detective in Botswana is the fifth in a series, the other four having largely escaped English attention (and availability). The Scots have had better luck: they've known about McCall Smith for several years, but it has taken his extraordinary and unexpected success in the US for word to have filtered back to England that he's a treasure of a writer whose books deserve immediate devouring." The Full Cupboard of Life The Full Cupboard of Life is the fifth in The No. 1 Ladies' Detective Agency series