Aspirin for its health effects for at least 2,400 years. In 1853, chemist Charles Frédéric Gerhardt treated the medicine sodium salicylate with acetyl chloride to produce acetylsalicylic acid for the first time. For the next fifty years, other chemists established the chemical structure and came up with more efficient methods to make it. In 1897, scientists at the Bayer company began studying acetylsalicylic acid as a less-irritating replacement medication for common salicylate medicines. By 1899, Bayer had named it "Aspirin" and sold it around the world. Aspirin's popularity grew over the first half of the twentieth century leading to competition between
The Indian in the Cupboard the Iroquois and Boone. Omri uses the trunk to bring Patrick back to the present and at the same time return the Iroquois to the past, but returning Patrick inadvertently drags the tornado back to Omri's room, destroying part of the house and neighborhood. In the chaos, the cupboard is damaged and the key lost. Omri's headmaster, who has been lurking outside the house hoping to catch evidence of Omri's secret, is struck on the head by debris, meaning that no one believes any of his ramblings about "tiny people." Boone and Ruby Lou realize they are stranded as tiny