Acetyl group known as paracetamol), and acetylsalicylic acid (better known as aspirin). The introduction of an acetyl group into a molecule is called acetylation. In biological organisms, acetyl groups are commonly transferred from acetyl-CoA to other organic molecules. Acetyl-CoA is an intermediate both in the biological synthesis and in the breakdown of many organic molecules. Acetyl-CoA is also created during the second stage of cellular respiration, the Krebs Cycle, by the action of pyruvate dehydrogenase on pyruvic acid. Histones and other proteins are often modified by acetylation. For example, on the DNA level, histone acetylation by acetyltransferases (HATs) causes an expansion of
The Indian in the Cupboard toys. He also possessed some of Jessica's magical abilities. Jessica had him create the cupboard, which he imbues with his hatred of plastic toys. This caused the cupboard to only bring plastic toys to life, which is why no other materials ever worked when Omri tried them in the cupboard. Omri meets one of the thatchers who worked on the roof when Jessica was dying, a man named Tom, and learns from him that Jessica let him in on the secret. She also gave him a little person to care for, a servant girl named Jenny from the 1800s who