Polio vaccine attenuated vaccine strains. In 1958, the National Institutes of Health created a special committee on live polio vaccines. The various vaccines were carefully evaluated for their ability to induce immunity to polio, while retaining a low incidence of neuropathogenicity in monkeys. Large-scale clinical trials performed in the Soviet Union in late 1950s to early 1960s by Mikhail Chumakov and his colleagues demonstrated safety and high efficacy of the vaccine. Based on these results, the Sabin strains were chosen for worldwide distribution. Fifty-seven nucleotide substitutions distinguish the attenuated Sabin 1 strain from its virulent parent (the Mahoney serotype), two nucleotide substitutions
Goodbye Bruce Lee: His Last Game of Death Goodbye Bruce Lee: His Last Game of Death Goodbye Bruce Lee: His Last Game of Death, also known as The New Game of Death and Legend of Bruce Lee, is a 1975 Bruceploitation martial arts film starring Bruce Li. A young man (Bruce Li) unwittingly gets wrapped up in a money scam. When he refuses to give the cash back, the bad guys kidnap his girlfriend and hold her hostage in the Tower Of Death. Once there, he is given two options. Watch his girlfriend get thrown off the top or fight various martial artists on 7 different levels to