Acetyl group known as paracetamol), and acetylsalicylic acid (better known as aspirin). The introduction of an acetyl group into a molecule is called acetylation. In biological organisms, acetyl groups are commonly transferred from acetyl-CoA to other organic molecules. Acetyl-CoA is an intermediate both in the biological synthesis and in the breakdown of many organic molecules. Acetyl-CoA is also created during the second stage of cellular respiration, the Krebs Cycle, by the action of pyruvate dehydrogenase on pyruvic acid. Histones and other proteins are often modified by acetylation. For example, on the DNA level, histone acetylation by acetyltransferases (HATs) causes an expansion of
The Indian in the Cupboard (film) fits the keyhole of his cupboard. He then looks for an object to lock in the cupboard and settles for the Indian figurine. The next morning, he hears a small tapping noise coming from the cupboard. Omri opens the cupboard and finds a small living person hiding in the corner. It is actually the Indian figure who has magically come to life in human form. Frightened by his large acquaintance, the Indian pulls out a dagger and points it at Omri. Shortly afterward, Omri's father comes in the room to help Omri get ready for school, forcing Omri to lock