Aspirin for its health effects for at least 2,400 years. In 1853, chemist Charles Frédéric Gerhardt treated the medicine sodium salicylate with acetyl chloride to produce acetylsalicylic acid for the first time. For the next fifty years, other chemists established the chemical structure and came up with more efficient methods to make it. In 1897, scientists at the Bayer company began studying acetylsalicylic acid as a less-irritating replacement medication for common salicylate medicines. By 1899, Bayer had named it "Aspirin" and sold it around the world. Aspirin's popularity grew over the first half of the twentieth century leading to competition between
The Indian in the Cupboard (film) puzzled to find the cupboard is missing. Omri's brother confesses he hid the cupboard in the downstairs crawlspace as means of getting back at Omri for hiding the ball his brother keeps his pet rat in. When Omri retrieves the cupboard, he discovers that the key is gone. That night, Omri and Patrick, along with Little Bear and Boone, watch a program on TV that shows a relentless slaughter of Indians by cowboys. Boone is enthusiastic at the sight of his "boys" killing the helpless Indians, while Little Bear watches in horror at the sight of his "people" being massacred.