Buster Capp Buster Capp Buster Capp is a British comic strip series which debuted on May 28, 1960, in the magazine "Buster" and ran until January 2000. It is a spin-off of Andy Capp, despite not being drawn by the original artist of that comic, Reg Smythe. The first artist was Bill Titcombe, but Hugh McNeill took over as artist after less than a year. After a few years Àngel Nadal took over and drew the strip until 1974, when he was followed by Reg Parlett. Tom Paterson in turn took over from Parlett in 1985 and drew the strip until 1990.
CAPP-Seq to quantify the previously identified mutations in the patient. CAPP-Seq can be applied to ctDNA from multiple blood samples at different time points in order to follow tumor evolution. A series of steps are involved in analysis of CAPP-Seq data from mutation detection to validation and open source software can do most of the analysis. After the first step of variant calling, germline and loss of heterozygosity (LOH) mutations are removed in CAPP-seq to reduce the background biases. Several statistical significance tests can be performed against background to all type of variant calling. For example, statistical significance of tumor-derived SNVs