Vaccine one of the vaccine components is more robust than the others and suppresses the growth and immune response to the other components. This phenomenon was first noted in the trivalent Sabin polio vaccine, where the amount of serotype 2 virus in the vaccine had to be reduced to stop it from interfering with the "take" of the serotype 1 and 3 viruses in the vaccine. This phenomenon has also been found to be a problem with the dengue vaccines currently being researched, where the DEN-3 serotype was found to predominate and suppress the response to DEN-1, −2 and −4 serotypes.
The Man Who Mistook His Wife for a Hat The Man Who Mistook His Wife for a Hat The Man Who Mistook His Wife for a Hat and Other Clinical Tales is a 1985 book by neurologist Oliver Sacks describing the case histories of some of his patients. Sacks chose the title of the book from the case study of one of his patients which he names "Dr. P" that has visual agnosia"," a neurological condition that leaves him unable to recognize even familiar faces and objects". Man Who Mistook His Wife for a Hat" became the basis of an opera of the same name by Michael Nyman, which