Vaccine one of the vaccine components is more robust than the others and suppresses the growth and immune response to the other components. This phenomenon was first noted in the trivalent Sabin polio vaccine, where the amount of serotype 2 virus in the vaccine had to be reduced to stop it from interfering with the "take" of the serotype 1 and 3 viruses in the vaccine. This phenomenon has also been found to be a problem with the dengue vaccines currently being researched, where the DEN-3 serotype was found to predominate and suppress the response to DEN-1, −2 and −4 serotypes.
Hib Sabin Hib Sabin Hib Sabin (born 1935) is an American sculptor and educator. He is known for his indigenous-style work in juniper wood. He carves spirit animal spirit bowls, spirit canoes, dream and dance sticks, and shamanistic masks. He lives in Santa Fe, New Mexico. Sabin received a BFA in Studio Art and Art History from University of Pennsylvania / Pennsylvania Academy of Fine Arts (coordinated program) and an MFA in Art History from the University of Pittsburgh. Sabin has taught art history at Shadyside Academy in Pittsburgh and at Franklin and Marshall College in Lancaster, Pennsylvania. He was an Associate