Sabin Vaccine Institute Sabin Vaccine Institute Sabin Vaccine Institute (Sabin), located in Washington, D.C., is a nonprofit (501(c)(3)) organization promoting global vaccine development, availability, and use. Through its work, Sabin hopes to reduce human suffering by preventing the spread of vaccine-preventable, communicable disease in humans through herd immunity, and also hopes to mitigate the poverty caused by these diseases. Founded in 1993 in honor of its eponym, Albert B. Sabin, creator of the oral polio vaccine, Sabin works to reduce "human suffering from vaccine-preventable and neglected tropical diseases (NTDs)." The organization endeavors to reach its goal via its three main programs: Sabin Vaccine
Smallpox vaccine sheep were used. In the late 1940s and early 1950s, Leslie Collier, an English microbiologist working at the Lister Institute of Preventive Medicine, developed a method for producing a heat-stable freeze-dried vaccine in powdered form. Collier added 0.5% phenol to the vaccine to reduce the number of bacterial contaminants but the key stage was to add 5% peptone to the liquid vaccine before it was dispensed into ampoules. This protected the virus during the freeze drying process. After drying the ampoules were sealed under nitrogen. Like other vaccines, once reconstituted it became ineffective after 1–2 days at ambient temperatures. However,