History of aspirin History of aspirin The history of aspirin (IUPAC name acetylsalicylic acid ) begins with its synthesis and manufacture in 1899. Before that, salicylic acid had been used medicinally since antiquity. Medicines made from willow and other salicylate-rich plants appear in clay tablets from ancient Sumer as well as the Ebers Papyrus from ancient Egypt. Hippocrates referred to their use of salicylic tea to reduce fevers around 400 BC, and were part of the pharmacopoeia of Western medicine in classical antiquity and the Middle Ages. Willow bark extract became recognized for its specific effects on fever, pain and inflammation in the
The Indian in the Cupboard the cupboard without Omri's knowledge, bring to life the plastic cowboy, who turns out to be a man named Boone from an entirely different place and time as Little Bear. Over Omri's objections, Patrick introduces Boone to Little Bear. The two tiny men mistrust one another from the start, with Boone deriding Little Bear as "savage" and "dirty." The antagonism comes to a head when Omri and Patrick introduce the duo to television; when Boone cheers the slaughter of Native Americans in an old Western, Little Bear shoots him in the chest with an arrow. Little Bear is immediately guilty,