Polio vaccine attenuated vaccine strains. In 1958, the National Institutes of Health created a special committee on live polio vaccines. The various vaccines were carefully evaluated for their ability to induce immunity to polio, while retaining a low incidence of neuropathogenicity in monkeys. Large-scale clinical trials performed in the Soviet Union in late 1950s to early 1960s by Mikhail Chumakov and his colleagues demonstrated safety and high efficacy of the vaccine. Based on these results, the Sabin strains were chosen for worldwide distribution. Fifty-seven nucleotide substitutions distinguish the attenuated Sabin 1 strain from its virulent parent (the Mahoney serotype), two nucleotide substitutions
My Name Is Bruce Entertainment will distribute both films. The title for the second film has since been changed to "Bruce vs. Frankenstein". In a message sent in January, 2010 to Ain't It Cool News, Campbell officially announced the sequel, stating that "principal photography begins this fall in Oregon." In April, Ted Raimi confirmed that he would be involved with the project. Campbell declared himself the director, saying, "no one will volunteer, so it's me." My Name Is Bruce My Name Is Bruce is a 2007 American comedy horror film directed, co-produced by and starring B movie cult actor Bruce Campbell. The film was