Polio vaccine is usually provided in vials containing 10–20 doses of vaccine. A single dose of oral polio vaccine (usually two drops) contains 1,000,000 infectious units of Sabin 1 (effective against PV1), 100,000 infectious units of the Sabin 2 strain, and 600,000 infectious units of Sabin 3. The vaccine contains small traces of antibiotics—neomycin and streptomycin—but does not contain preservatives. In a generic sense, vaccination works by priming the immune system with an 'immunogen'. Stimulating immune response, by use of an infectious agent, is known as immunization. The development of immunity to polio efficiently blocks person-to-person transmission of wild poliovirus, thereby protecting
Alvah Sabin Alvah Sabin Alvah Sabin (October 23, 1793 – January 22, 1885) was an American politician and clergyman. He served as a United States Representative from Vermont. Sabin was born in Georgia, Vermont to Benjamin Sabin and Polly McMaster Sabin, and was educated in the common schools. He was also a member of the Vermont militia and served during the War of 1812. Sabin also attended the University of Vermont in Burlington, which awarded him the honorary degree of master of arts in 1826. After the war, Sabin studied theology in Philadelphia and graduated from Columbian College (now George Washington University),