History of aspirin History of aspirin The history of aspirin (IUPAC name acetylsalicylic acid ) begins with its synthesis and manufacture in 1899. Before that, salicylic acid had been used medicinally since antiquity. Medicines made from willow and other salicylate-rich plants appear in clay tablets from ancient Sumer as well as the Ebers Papyrus from ancient Egypt. Hippocrates referred to their use of salicylic tea to reduce fevers around 400 BC, and were part of the pharmacopoeia of Western medicine in classical antiquity and the Middle Ages. Willow bark extract became recognized for its specific effects on fever, pain and inflammation in the
The Indian in the Cupboard meets Tom's daughter, who is wearing the long-lost earrings. Omri realizes that Jessica gave the earrings to Tom, who gave them to his daughter without knowing they were stolen. Having solved the mystery, he decides not to tell Tom's daughter the story of the earrings. Omri returns home to find that his father, while rebuilding Omri's bedroom, found the key, the cupboard, and the plastic figure of Little Bear and locked the toy in the cupboard, where he was shocked when Little Bear came to life. He has since been too frightened to open the cupboard while Little Bear called