Aspirin for its health effects for at least 2,400 years. In 1853, chemist Charles Frédéric Gerhardt treated the medicine sodium salicylate with acetyl chloride to produce acetylsalicylic acid for the first time. For the next fifty years, other chemists established the chemical structure and came up with more efficient methods to make it. In 1897, scientists at the Bayer company began studying acetylsalicylic acid as a less-irritating replacement medication for common salicylate medicines. By 1899, Bayer had named it "Aspirin" and sold it around the world. Aspirin's popularity grew over the first half of the twentieth century leading to competition between
Pyrophosphoric acid it is difficult to recrystallise from the melt. In aqueous solution pyrophosphoric acid like all polyphosphoric acids hydrolyses and eventually an equilibrium is established between phosphoric acid pyrophosphoric acid and polyphosphoric acids. When highly diluted, an aqueous solution of pyrophosphoric acid contains only phosphoric acid. Pyrophosphoric acid is a medium strong inorganic acid. Anions, salts, and esters of pyrophosphoric acid are called pyrophosphates. While pyrophosporic acid is corrosive, it is not known to be otherwise toxic. The name pyrophosphoric acid was given by a "Mr. Clarke of Glasgow" in 1827 who is credited with its discovery following the heating to