Vaccine one of the vaccine components is more robust than the others and suppresses the growth and immune response to the other components. This phenomenon was first noted in the trivalent Sabin polio vaccine, where the amount of serotype 2 virus in the vaccine had to be reduced to stop it from interfering with the "take" of the serotype 1 and 3 viruses in the vaccine. This phenomenon has also been found to be a problem with the dengue vaccines currently being researched, where the DEN-3 serotype was found to predominate and suppress the response to DEN-1, −2 and −4 serotypes.
Tukiki and His Search for a Merry Christmas given gifts which he eventually takes back to give to his selfish arctic friends. The thoughtful giving of gifts brings about a change in Tukiki's homeland and suddenly harmony reigns where once was none, and through Tukiki's act of love, the true meaning of Christmas is discovered. 1980 Genie Awards: "Tukiki and His Search for a Merry Christmas" was released on VHS by Embassy Home Entertainment in 1986 which has long been out of print. On August 12, 2008, it was released as a manufacture-on-demand DVD-R as part of the "Holiday Classics" series by Phoenix Learning Group, Inc. Tukiki and