Vaccine one of the vaccine components is more robust than the others and suppresses the growth and immune response to the other components. This phenomenon was first noted in the trivalent Sabin polio vaccine, where the amount of serotype 2 virus in the vaccine had to be reduced to stop it from interfering with the "take" of the serotype 1 and 3 viruses in the vaccine. This phenomenon has also been found to be a problem with the dengue vaccines currently being researched, where the DEN-3 serotype was found to predominate and suppress the response to DEN-1, −2 and −4 serotypes.
Sabin Vaccine Institute "childhood cognitive development among the poor, thereby reinforcing poverty." Sabin works with experts and organizations from around the world to advance knowledge of both infectious diseases and the vaccines that can prevent them. Through the International Association of Immunization Managers (IAIM) Network, Sabin arranges international forums to improve the success rates of immunization programs. Sabin serves as the Secretariat for the Coalition against Typhoid whose mission is to raise awareness of Typhoid and Salmonellosis. First awarded in 1994, the Albert B. Sabin Gold Medal is presented by Sabin each year to one or more persons who have made a major