Herpes zoster ophthalmicus Herpes zoster ophthalmicus Herpes zoster ophthalmicus (HZO) and also known as ophthalmic zoster is a disease characterised by reactivation of dormant varicella zoster virus residing within the ophthalmic nerve (the first division of the trigeminal nerve). This condition is an important subtype of shingles, representing 15% of all cases. Herpes zoster ophthalmicus is transmitted via direct contact or droplets. Varicella zoster virus is a DNA virus which produces acidophilic intranuclear inclusion bodies. The virus is neurotrophic in nature. The frontal nerve is more commonly affected than the nasociliary nerve or lacrimal nerve. Anterior uveitis develops in 40–50% of cases with
Contagious disease illustrated classically by tuberculosis, which is clearly transmissible from person to person, but was not classically considered a contagious disease. In the present day, most sexually transmitted diseases are considered contagious, but only some of them are subject to medical isolation. Originally, the term referred to a "contagion" (a derivative of 'contact') or disease transmissible only by direct physical contact. In the modern day, the term has sometimes been broadened to encompass "any" communicable or infectious disease. Often the word can only be understood in context, where it is used to emphasise very infectious, easily transmitted, or especially severe communicable