Acetyl group known as paracetamol), and acetylsalicylic acid (better known as aspirin). The introduction of an acetyl group into a molecule is called acetylation. In biological organisms, acetyl groups are commonly transferred from acetyl-CoA to other organic molecules. Acetyl-CoA is an intermediate both in the biological synthesis and in the breakdown of many organic molecules. Acetyl-CoA is also created during the second stage of cellular respiration, the Krebs Cycle, by the action of pyruvate dehydrogenase on pyruvic acid. Histones and other proteins are often modified by acetylation. For example, on the DNA level, histone acetylation by acetyltransferases (HATs) causes an expansion of
The Indian in the Cupboard cupboard. Omri believes that the final bundle must contain the missing earrings, but in fact, it contains another tiny person, fast asleep. Before he can investigate further, he is called to Tom's home. Tom has fallen from the roof and is on the verge of death, but asked for Omri to tell him the final secret: before she died, Jessica had him search for a plastic figure of herself. He bought dozens of figurines before finally finding the right one. Jessica kept the figure of herself but told him to take care of the other plastic figures, saying, "This is