Albert Sabin Albert Sabin Albert Bruce Sabin (born Abram Saperstein; August 26, 1906 – March 3, 1993) was a Polish American medical researcher, best known for developing the oral polio vaccine which has played a key role in nearly eradicating the disease. Sabin was born in Białystok, Poland, then part of the Russian Empire, to Polish-Jewish parents, Jacob Saperstein and Tillie Krugman. In 1921, he emigrated with his family as "Abram Saperstejn" on the S/S "Lapland" which sailed from Antwerp, Belgium, to the Port of New York. In 1930, he became a naturalized citizen of the United States and changed his name
Smallpox vaccine sheep were used. In the late 1940s and early 1950s, Leslie Collier, an English microbiologist working at the Lister Institute of Preventive Medicine, developed a method for producing a heat-stable freeze-dried vaccine in powdered form. Collier added 0.5% phenol to the vaccine to reduce the number of bacterial contaminants but the key stage was to add 5% peptone to the liquid vaccine before it was dispensed into ampoules. This protected the virus during the freeze drying process. After drying the ampoules were sealed under nitrogen. Like other vaccines, once reconstituted it became ineffective after 1–2 days at ambient temperatures. However,