Nitric acid fuming nitric acid at concentrations above 86%. Nitric acid is the primary reagent used for nitration – the addition of a nitro group, typically to an organic molecule. While some resulting nitro compounds are shock- and thermally-sensitive explosives, a few are stable enough to be used in munitions and demolition, while others are still more stable and used as pigments in inks and dyes. Nitric acid is also commonly used as a strong oxidizing agent. Commercially available nitric acid is an azeotrope with water at a concentration of 68% HNO, which is the ordinary concentrated nitric acid of commerce. This
Bromopyruvic acid Bromopyruvic acid Bromopyruvic acid is the organic compound with the formula BrCHCOCOH. This colorless solid is the brominated derivative of pyruvic acid. It bears structural similarity to lactic acid and pyruvic acid. It has been investigated as a metabolic poison and an anticancer agent. Like other α-bromoketones, it is a strong alkylating agent. The pyruvate transporter system can be used to deliver bromopyruvate inside trypanosomal cells. Once intracellular, the primary target of 3BP is glyceraldehyde-3-phosphate dehydrogenase, which is highly sensitive to inhibition by bromopyruvate. The pyruvate transporter system, which is known to be overexpressed in cancer cells, was later identified