The Claws of Axos standard. The story includes interior scenes inside the TARDIS for the first time in the Pertwee era of the show. The configuration of the TARDIS set-up is unique for this adventure. The TARDIS monitor appears to be a circular screen embedded in one of the 'roundels' in the console room wall, rather than the traditional rectangular screen (this feature is seen again once, a year later, on the unique set built for "The Time Monster"). The doors of the console room do not open directly into the exterior as in all other adventures; instead they open into a corridor that
Circular permutation in proteins a class of proteins involved in sphingolipid catabolism and antigen presentation of lipids in humans. Chris Ponting and Robert Russell identified a circularly permuted version of a saposin inserted into plant aspartic proteinase, which they nicknamed swaposin. Saposin and swaposin were the first known case of two natural genes related by a circular permutation. Hundreds of examples of protein pairs related by a circular permutation were subsequently discovered in nature or produced in the laboratory. As of February 2012, the Circular Permutation Database contains 2,238 circularly permuted protein pairs with known structures, and many more are known without structures. The