Vaccine one of the vaccine components is more robust than the others and suppresses the growth and immune response to the other components. This phenomenon was first noted in the trivalent Sabin polio vaccine, where the amount of serotype 2 virus in the vaccine had to be reduced to stop it from interfering with the "take" of the serotype 1 and 3 viruses in the vaccine. This phenomenon has also been found to be a problem with the dengue vaccines currently being researched, where the DEN-3 serotype was found to predominate and suppress the response to DEN-1, −2 and −4 serotypes.
Grass for His Pillow before the pass is closed by snow. Once Spring thaws the snow, Kaede excuses herself from Fujiwara, stating her intention to visit Arai, her overlord, to discuss her future. He reluctantly agrees, and she travels via Terayama, as she has heard that Takeo is there. They meet, and as Takeo is under a death sentence from the Tribe, Kaede sends Shizuka and Kondo away. Against advice, Takeo and Kaede marry at Terayama. Grass for His Pillow Grass for His Pillow is the second novel in Lian Hearn's popular Tales of the Otori trilogy, published in 2003. The events in the