Acetyl group known as paracetamol), and acetylsalicylic acid (better known as aspirin). The introduction of an acetyl group into a molecule is called acetylation. In biological organisms, acetyl groups are commonly transferred from acetyl-CoA to other organic molecules. Acetyl-CoA is an intermediate both in the biological synthesis and in the breakdown of many organic molecules. Acetyl-CoA is also created during the second stage of cellular respiration, the Krebs Cycle, by the action of pyruvate dehydrogenase on pyruvic acid. Histones and other proteins are often modified by acetylation. For example, on the DNA level, histone acetylation by acetyltransferases (HATs) causes an expansion of
The Indian in the Cupboard tiny figures and awareness that, though small, they were real people who ought not to be so manipulated." Despite the wide range of views on this novel, little information exists about any challenges the author faced in publishing it. At one time classrooms and libraries widely accepted the book. On Omri’s ninth birthday, his best friend Patrick gives Omri the disappointing gift of a small plastic Indian figurine. Omri also receives a white metal medicine cupboard from his brother. The only key in the house that fits the cupboard's lock is the key to Omri's great-grandmother's jewelry box. Omri puts