Vaccine one of the vaccine components is more robust than the others and suppresses the growth and immune response to the other components. This phenomenon was first noted in the trivalent Sabin polio vaccine, where the amount of serotype 2 virus in the vaccine had to be reduced to stop it from interfering with the "take" of the serotype 1 and 3 viruses in the vaccine. This phenomenon has also been found to be a problem with the dengue vaccines currently being researched, where the DEN-3 serotype was found to predominate and suppress the response to DEN-1, −2 and −4 serotypes.
Samuel Katz (pediatrician) the Albert B. Sabin Gold Medal awarded by the Sabin Vaccine Institute for his contributions to vaccine discoveries during his career. Samuel Katz (pediatrician) Samuel L. Katz (born 1927) is an American pediatrician and virologist whose career has been devoted to infectious disease research, focusing principally on vaccine research and development. Katz is currently the Wilburt Cornell Davison Professor and Chairman Emeritus of Pediatrics at Duke University. October 15, 1958 the first Measles Vaccine is tested in a Boston lab. The first version of the lab’s vaccine on mentally retarded and disabled children at a school outside of Boston. He