Polio vaccine attenuated vaccine strains. In 1958, the National Institutes of Health created a special committee on live polio vaccines. The various vaccines were carefully evaluated for their ability to induce immunity to polio, while retaining a low incidence of neuropathogenicity in monkeys. Large-scale clinical trials performed in the Soviet Union in late 1950s to early 1960s by Mikhail Chumakov and his colleagues demonstrated safety and high efficacy of the vaccine. Based on these results, the Sabin strains were chosen for worldwide distribution. Fifty-seven nucleotide substitutions distinguish the attenuated Sabin 1 strain from its virulent parent (the Mahoney serotype), two nucleotide substitutions
My Name Is Bruce My Name Is Bruce My Name Is Bruce is a 2007 American comedy horror film directed, co-produced by and starring B movie cult actor Bruce Campbell. The film was written by Mark Verheiden. It had a theatrical release in October 2008, followed by DVD and Blu-ray releases on February 10, 2009. Although Sam Raimi, with whom Bruce frequently collaborates, is not involved with this production, much of the film is in the vein of the "Evil Dead" series. Ted Raimi (Sam's brother), also a frequent collaborator, appears in this film. Campbell has shown several minutes of the movie during some