Polio vaccine attenuated vaccine strains. In 1958, the National Institutes of Health created a special committee on live polio vaccines. The various vaccines were carefully evaluated for their ability to induce immunity to polio, while retaining a low incidence of neuropathogenicity in monkeys. Large-scale clinical trials performed in the Soviet Union in late 1950s to early 1960s by Mikhail Chumakov and his colleagues demonstrated safety and high efficacy of the vaccine. Based on these results, the Sabin strains were chosen for worldwide distribution. Fifty-seven nucleotide substitutions distinguish the attenuated Sabin 1 strain from its virulent parent (the Mahoney serotype), two nucleotide substitutions
Hib Sabin Professor of studio art and art history at Dickinson College in Carlisle, Pennsylvania. Sabin has been creating art since 1957. His art is inspired by an interest in shamanism. He has had at least twelve one-man exhibitions. In July 2003, he was the subject of an extensive article in "Southwest Art" magazine. His work has been displayed by the Port of Seattle at Seattle–Tacoma International Airport. Hib Sabin has had twelve one-man exhibitions since becoming an artist. He has been represented by the following galleries: Hib Sabin Hib Sabin (born 1935) is an American sculptor and educator. He is known