Aspirin for its health effects for at least 2,400 years. In 1853, chemist Charles Frédéric Gerhardt treated the medicine sodium salicylate with acetyl chloride to produce acetylsalicylic acid for the first time. For the next fifty years, other chemists established the chemical structure and came up with more efficient methods to make it. In 1897, scientists at the Bayer company began studying acetylsalicylic acid as a less-irritating replacement medication for common salicylate medicines. By 1899, Bayer had named it "Aspirin" and sold it around the world. Aspirin's popularity grew over the first half of the twentieth century leading to competition between
The Indian in the Cupboard the nurse in the cupboard and bring her to life. The nurse, called Matron, believing she has has dozed off while on duty, saves Little Bear's life. Matron also announces that Bright Stars is pregnant and the boys decide that it would be safer to keep Bright Stars with them until after the baby is born, rather than return her to her war-torn village. Patrick brings the cowboy Boone back to life through the cupboard in order to help Bright Stars care for Little Bear. Little Bear tells Boone about the troubles his people are suffering during their war with