Prodrug not its intended target. This reduces adverse or unintended effects of a drug, especially important in treatments like chemotherapy, which can have severe unintended and undesirable side effects. Many herbal extracts historically used in medicine contain glycosides (sugar derivatives) of the active agent, which are hydrolyzed in the intestines to release the active and more bioavailable aglycone. For example, salicin is a β-D-glucopyranoside that is cleaved by esterases to release salicylic acid. Aspirin, acetylsalicylic acid, first made by Felix Hoffmann at Bayer in 1897, is a synthetic prodrug of salicylic acid. However, in other cases, such as codeine and morphine,
Cupboard love by physiologist, Ivan Pavlov. It supports assumptions that form the foundation of behaviorism. These basic ideas suggest that all learning occurs through interactions within the environment, and that environment shapes behavior. Various similarities exist between cupboard love and classical conditioning. Pavlov, known for Pavlov's dog experiment, discovered that his dog would salivate at the sound of a bell, associating the ringing with food. Eventually, the dog would salivate each time he heard the bell ring. When there was no food, the dog would still show affection to Pavlov in an attempt to be fed. Similarly, the cupboard love theory suggests