Shingles caused by varicella-zoster was regarded as rare disease, mostly related to childhood chickenpox. However, meningoencephalitis caused by varicella-zoster is increasingly recognized as a predominant cause of ME among immunocompetent adults in non-epidemic circumstances. Diagnosis of complications of varicella-zoster, particularly in cases where the disease reactivates after years or decades of latency, are difficult. A rash (shingles) can be present or absent. Symptoms vary, and there is significant overlap in symptoms with herpes-simplex symptoms. Although DNA analysis techniques such as polymerase chain reaction (PCR) can be used to look for DNA of herpesviruses in spinal fluid or blood, the results may
Center for Disease Dynamics, Economics & Policy at the Center for Disease Dynamics, Economics & Policy (CDDEP), in Washington, DC and New Delhi, provides technical support to each working group, creates links within the GARP network and involves the working groups in global discussions and policy development. GARP is a CDDEP project, funded by the Bill & Melinda Gates Foundation. The Affordable Medicines Facility-malaria (AMFm) is an innovative financing mechanism designed to expand access to the most effective treatment for malaria, artemisinin-based combination therapies (ACTs) through the public, private and NGO sectors. It will reduce the use of drugs that no longer work because of drug resistance,