Vaccine one of the vaccine components is more robust than the others and suppresses the growth and immune response to the other components. This phenomenon was first noted in the trivalent Sabin polio vaccine, where the amount of serotype 2 virus in the vaccine had to be reduced to stop it from interfering with the "take" of the serotype 1 and 3 viruses in the vaccine. This phenomenon has also been found to be a problem with the dengue vaccines currently being researched, where the DEN-3 serotype was found to predominate and suppress the response to DEN-1, −2 and −4 serotypes.
Chris Sabin Chris Sabin Joshua Harter (born February 4, 1982) better known by his ring name Chris Sabin, is an American professional wrestler. He is best known for his work in Total Nonstop Action Wrestling (TNA) and currently works most notably for Ring of Honor (ROH). After being trained by Scott D'Amore, Sabin debuted in 2000 for Border City Wrestling, and quickly began competing for numerous other independent promotions. In 2003, Sabin joined TNA, and quickly won the TNA X Division Championship, which he later unified with the WWA International Cruiserweight Championship. In 2004, he also wrestled for Ring of Honor. In