Aspirin for its health effects for at least 2,400 years. In 1853, chemist Charles Frédéric Gerhardt treated the medicine sodium salicylate with acetyl chloride to produce acetylsalicylic acid for the first time. For the next fifty years, other chemists established the chemical structure and came up with more efficient methods to make it. In 1897, scientists at the Bayer company began studying acetylsalicylic acid as a less-irritating replacement medication for common salicylate medicines. By 1899, Bayer had named it "Aspirin" and sold it around the world. Aspirin's popularity grew over the first half of the twentieth century leading to competition between
The Skeleton in the Cupboard (Yes Minister) has to hand a list of the standard government reasons for exempting information from the 30-year rule: it covers every document in the file. The Skeleton in the Cupboard (Yes Minister) "The Skeleton in the Cupboard" is the seventeenth episode of the BBC comedy series "Yes Minister" and was first broadcast 25 November 1982. Jim Hacker is chairing a meeting with his senior officials. One item on the agenda is the disciplinary action to be taken against the South Derbyshire local authority for failing to complete its statutory returns and supply required information. Sir Humphrey Appleby regards this as a