Acetyl group known as paracetamol), and acetylsalicylic acid (better known as aspirin). The introduction of an acetyl group into a molecule is called acetylation. In biological organisms, acetyl groups are commonly transferred from acetyl-CoA to other organic molecules. Acetyl-CoA is an intermediate both in the biological synthesis and in the breakdown of many organic molecules. Acetyl-CoA is also created during the second stage of cellular respiration, the Krebs Cycle, by the action of pyruvate dehydrogenase on pyruvic acid. Histones and other proteins are often modified by acetylation. For example, on the DNA level, histone acetylation by acetyltransferases (HATs) causes an expansion of
The Cupboard Under the Stairs generalized statements as to the detailed nature of the work carried on there, emphasizing only that it is experimental." The Cupboard Under the Stairs The Cupboard Under the Stairs is a Miles Franklin Award-winning novel by Australian author George Turner. This novel shared the award with "The Well Dressed Explorer" by Thea Astley. The novel tells the story of Harry White, who attempts to rebuild his life after spending six years in a mental institution. The novel carries the following dedication: "To Betty and Lindsay Bloomfield for one reason and another". The author added the following note: "Kilkalla is not