Acetyl group known as paracetamol), and acetylsalicylic acid (better known as aspirin). The introduction of an acetyl group into a molecule is called acetylation. In biological organisms, acetyl groups are commonly transferred from acetyl-CoA to other organic molecules. Acetyl-CoA is an intermediate both in the biological synthesis and in the breakdown of many organic molecules. Acetyl-CoA is also created during the second stage of cellular respiration, the Krebs Cycle, by the action of pyruvate dehydrogenase on pyruvic acid. Histones and other proteins are often modified by acetylation. For example, on the DNA level, histone acetylation by acetyltransferases (HATs) causes an expansion of
The Indian in the Cupboard people in the far future, unable to return home without the key. They attempt to make a life with one another, eventually confessing their love. They are resigned to their fate, but long to return home and be properly married. Omri, by sheer luck, finds the key in the bushes and uses it to summon all of the group's friends for Boone and Ruby Lou's wedding before sending everyone home for what he promises will be the final time. Afterwards Omri asks his parents for a safe-deposit box, into which he puts the key, the cupboard, and a copy of