Polio vaccine is usually provided in vials containing 10–20 doses of vaccine. A single dose of oral polio vaccine (usually two drops) contains 1,000,000 infectious units of Sabin 1 (effective against PV1), 100,000 infectious units of the Sabin 2 strain, and 600,000 infectious units of Sabin 3. The vaccine contains small traces of antibiotics—neomycin and streptomycin—but does not contain preservatives. In a generic sense, vaccination works by priming the immune system with an 'immunogen'. Stimulating immune response, by use of an infectious agent, is known as immunization. The development of immunity to polio efficiently blocks person-to-person transmission of wild poliovirus, thereby protecting
Cold War tensions and the polio vaccine flew to Leningrad in June, 1956. As a result of a cooperation of Sabin and Chumakov in Leningrad, Sabin was able to test his attenuated vaccine when funding in America was declined. While Sabin was working behind the Iron Curtain, the Sabin-Chumakov vaccine was determined to be safe and effective. Cold War tensions caused Western scientists to refuse the reports from the Russians about the effectiveness of the Sabin vaccine. However, mass vaccinations of Sabin's vaccine spread throughout Eastern Europe from 1960–1963. Just as some Soviet virologists did not trust the Western Salk vaccine, Americans had similar reservations about the