Aspirin for its health effects for at least 2,400 years. In 1853, chemist Charles Frédéric Gerhardt treated the medicine sodium salicylate with acetyl chloride to produce acetylsalicylic acid for the first time. For the next fifty years, other chemists established the chemical structure and came up with more efficient methods to make it. In 1897, scientists at the Bayer company began studying acetylsalicylic acid as a less-irritating replacement medication for common salicylate medicines. By 1899, Bayer had named it "Aspirin" and sold it around the world. Aspirin's popularity grew over the first half of the twentieth century leading to competition between
The Indian in the Cupboard (film) the cupboard and keep the Indian a secret. When Omri arrives home from school, he is upset to discover that the Indian has returned to its original toy form. When he goes to bed, Omri once more hears the tapping noise he heard that morning. He opens the cupboard to find the Indian alive once more. The Indian is again initially frightened of Omri but warms up to him, thinking Omri is a great spirit in a child's form, as the two begin talking, slowly forming a friendship. The Indian reveals himself as an English-speaking, 18th-century Iroquois Indian named Little