Vaccine one of the vaccine components is more robust than the others and suppresses the growth and immune response to the other components. This phenomenon was first noted in the trivalent Sabin polio vaccine, where the amount of serotype 2 virus in the vaccine had to be reduced to stop it from interfering with the "take" of the serotype 1 and 3 viruses in the vaccine. This phenomenon has also been found to be a problem with the dengue vaccines currently being researched, where the DEN-3 serotype was found to predominate and suppress the response to DEN-1, −2 and −4 serotypes.
Sabin Merino Sabin Merino Sabin Merino Zuloaga (; ; born 4 January 1992), known simply as Sabin, is a Spanish professional footballer who plays for CD Leganés on loan from Athletic Bilbao mainly as a left winger. Born in Urduliz, Biscay, Basque Country, Sabin graduated from Danok Bat CF's youth setup after spells at Athletic Bilbao's Lezama and American team Javanon FC. In the summer of 2011 he returned to the "Lions", and made his debut as a senior with the farm team in Tercera División. On 21 June 2013, Sabin was promoted to the reserves in Segunda División B. On 29