History of aspirin History of aspirin The history of aspirin (IUPAC name acetylsalicylic acid ) begins with its synthesis and manufacture in 1899. Before that, salicylic acid had been used medicinally since antiquity. Medicines made from willow and other salicylate-rich plants appear in clay tablets from ancient Sumer as well as the Ebers Papyrus from ancient Egypt. Hippocrates referred to their use of salicylic tea to reduce fevers around 400 BC, and were part of the pharmacopoeia of Western medicine in classical antiquity and the Middle Ages. Willow bark extract became recognized for its specific effects on fever, pain and inflammation in the
Phosphorous acid downy mildew. Anti-microbial products containing salts of phosphorous acid are marketed in Australia as 'Yates Anti-Rot'; and in the United States of America, for example, aluminum salts of the monoethyl ester of phosphorous acid (known generically as 'Fosetyl-Al') are sold under the trade name 'Aliette' and potassium salts of phosphorous acid (known generically as potassium phosphite) are sold under the trade name ProPhyt. Phosphorous acid and its salts, unlike phosphoric acid, are somewhat toxic and should be handled carefully. The IUPAC (mostly organic) name is phosphonic acid. This nomenclature is commonly reserved for substituted derivatives, that is, organic group bonded