History of aspirin History of aspirin The history of aspirin (IUPAC name acetylsalicylic acid ) begins with its synthesis and manufacture in 1899. Before that, salicylic acid had been used medicinally since antiquity. Medicines made from willow and other salicylate-rich plants appear in clay tablets from ancient Sumer as well as the Ebers Papyrus from ancient Egypt. Hippocrates referred to their use of salicylic tea to reduce fevers around 400 BC, and were part of the pharmacopoeia of Western medicine in classical antiquity and the Middle Ages. Willow bark extract became recognized for its specific effects on fever, pain and inflammation in the
Pyrophosphoric acid it is difficult to recrystallise from the melt. In aqueous solution pyrophosphoric acid like all polyphosphoric acids hydrolyses and eventually an equilibrium is established between phosphoric acid pyrophosphoric acid and polyphosphoric acids. When highly diluted, an aqueous solution of pyrophosphoric acid contains only phosphoric acid. Pyrophosphoric acid is a medium strong inorganic acid. Anions, salts, and esters of pyrophosphoric acid are called pyrophosphates. While pyrophosporic acid is corrosive, it is not known to be otherwise toxic. The name pyrophosphoric acid was given by a "Mr. Clarke of Glasgow" in 1827 who is credited with its discovery following the heating to