Polio vaccine polio and post-polio syndrome. In the United States, vaccine is administered along with the tetanus, diphtheria, and acellular pertussis vaccines (DTaP) and a pediatric dose of hepatitis B vaccine. In the UK, IPV is combined with tetanus, diphtheria, pertussis, and "Haemophilus influenzae" type b vaccines. OPV is an attenuated vaccine, produced by the passage of the virus through nonhuman cells at a subphysiological temperature, which produces spontaneous mutations in the viral genome. Oral polio vaccines were developed by several groups, one of which was led by Albert Sabin. Other groups, led by Hilary Koprowski and H.R. Cox, developed their own
The Heroic Age of American Invention The Heroic Age of American Invention The Heroic Age of American Invention is a 1961 science book for children by L. Sprague de Camp, published by Doubleday. It was reprinted in 1993 by Barnes & Noble under the title "Heroes of American Invention". By "heroic age" the author means the era of American history in which individual initiative and enterprise constituted the primary thread in technical innovation, roughly from the early 19th century until mass production and corporate enterprise outpaced that of the individual around the time of World War I. The story of innovation is told through the biographies