Polio vaccine poliomyelitis per million doses given. This compares with 5,000 cases per million who are paralysed following a polio infection. Both are generally safe to give during pregnancy and in those who have HIV/AIDS but are otherwise well. The first polio vaccine was the inactivated polio vaccine. It was developed by Jonas Salk and came into use in 1955. The oral polio vaccine was developed by Albert Sabin and came into commercial use in 1961. They are on the World Health Organization's List of Essential Medicines, the most effective and safe medicines needed in a health system. The wholesale cost in
Albert Sabin humanitarian benefit. Indeed, it was not clear to many that the vaccine was an American one, financed by U.S. dollars, as it was not widely available to ordinary Americans. Sabin also developed vaccines against other viral diseases, including encephalitis and dengue. In addition, he investigated possible links between viruses and some forms of cancer. In 1983, Sabin developed calcification of the cervical spine, which caused paralysis and intense pain. Sabin revealed in a television interview that the experience had made him decide to spend the rest of his life working on alleviating pain. This condition was successfully treated by surgery