Varicella (video game) and Playing Cadre's Varicella", and by Dr. Wendy Morgan in her 2003 paper "Touching (on) Character: New Engagements in New Media Narratives". Cadre himself claimed in a January 2002 interview that it was the best game he had written up to that point: Varicella (video game) Varicella is a 1999 work of interactive fiction by Adam Cadre, distributed in z-code format as freeware. It is set in an alternate history which features roughly modern technology mixed with Renaissance-style principalities and court politics. The characters of Varicella use contemporary language from their home in a Renaissance castle, continuing the contrast between
Long-term memory is important for the persistence of long-term memories. The long-term stabilization of synaptic changes is also determined by a parallel increase of pre- and postsynaptic structures such as axonal bouton, dendritic spine and postsynaptic density. On the molecular level, an increase of the postsynaptic scaffolding proteins PSD-95 and Homer1c has been shown to correlate with the stabilization of synaptic enlargement. The cAMP response element-binding protein (CREB) is a transcription factor which is believed to be important in consolidating short-term to long-term memories, and which is believed to be downregulated in Alzheimer's disease. A couple of studies have had results that