Polio vaccine attenuated vaccine strains. In 1958, the National Institutes of Health created a special committee on live polio vaccines. The various vaccines were carefully evaluated for their ability to induce immunity to polio, while retaining a low incidence of neuropathogenicity in monkeys. Large-scale clinical trials performed in the Soviet Union in late 1950s to early 1960s by Mikhail Chumakov and his colleagues demonstrated safety and high efficacy of the vaccine. Based on these results, the Sabin strains were chosen for worldwide distribution. Fifty-seven nucleotide substitutions distinguish the attenuated Sabin 1 strain from its virulent parent (the Mahoney serotype), two nucleotide substitutions
His Name Is... Savage His Name Is... Savage His Name Is... Savage is a 40-page, magazine-format comics novel released in 1968 as a precursor to the modern graphic novel. Created by the veteran American comic book artist Gil Kane, who conceived, plotted and illustrated the project, and writer Archie Goodwin, who scripted under the pseudonym Robert Franklin, the black-and-white magazine was published by Kane's Adventure House Press, and distributed to newsstands. "His Name Is... Savage" #1 (June 1968), the sole issue published, was the first full-length comics story in a non-comic book format since 1950, when St. John Publications issued the digest-sized hardboiled detective