Polio vaccine attenuated vaccine strains. In 1958, the National Institutes of Health created a special committee on live polio vaccines. The various vaccines were carefully evaluated for their ability to induce immunity to polio, while retaining a low incidence of neuropathogenicity in monkeys. Large-scale clinical trials performed in the Soviet Union in late 1950s to early 1960s by Mikhail Chumakov and his colleagues demonstrated safety and high efficacy of the vaccine. Based on these results, the Sabin strains were chosen for worldwide distribution. Fifty-seven nucleotide substitutions distinguish the attenuated Sabin 1 strain from its virulent parent (the Mahoney serotype), two nucleotide substitutions
His Name Is Legs (Ladies and Gentlemen) for "His Name Is Legs" included tack piano, played by Canadian musician David Foster, and a new horn arrangement, played by Scott and Chuck Findley, another member of Harrison's tour band the previous year. Scott and Findley recorded their contributions at A&M Studios over 2–3 June, with each musician overdubbing two horn parts.<ref name="Extra Texture/YouTube">George Harrison interview, "Rockweek", (retrieved 13 September 2013).</ref> The released recording begins with an introductory bass riff from Weeks, which is then joined by Foster's tack piano. Commentators note the lack of clarity in the mix, which author Elliot Huntley attributes to the "three-pronged piano attack"