Shingles caused by varicella-zoster was regarded as rare disease, mostly related to childhood chickenpox. However, meningoencephalitis caused by varicella-zoster is increasingly recognized as a predominant cause of ME among immunocompetent adults in non-epidemic circumstances. Diagnosis of complications of varicella-zoster, particularly in cases where the disease reactivates after years or decades of latency, are difficult. A rash (shingles) can be present or absent. Symptoms vary, and there is significant overlap in symptoms with herpes-simplex symptoms. Although DNA analysis techniques such as polymerase chain reaction (PCR) can be used to look for DNA of herpesviruses in spinal fluid or blood, the results may
Center for Scientific and Technical Creativity of the Youth Center for Scientific and Technical Creativity of the Youth Centers for Scientific and Technical Creativity of the Youth , NTTM) were established in the late Soviet Union during "perestroika" as enterprises whose goal was commercialization of science and technology. Other translations of the Russian term are Scientific and Technical Creativity of Youth Center, Youth Center for Scientific Creativity, etc. The Centers were introduced by a joint decree of the USSR Council of Ministers, All-Union Central Council of Trade Unions, and Komsomol Central Committee no. 321 (March 13, 1987) "об образовании единой общегосударственной системы научно-технического творчества молодежи". They were established as