Vaccine one of the vaccine components is more robust than the others and suppresses the growth and immune response to the other components. This phenomenon was first noted in the trivalent Sabin polio vaccine, where the amount of serotype 2 virus in the vaccine had to be reduced to stop it from interfering with the "take" of the serotype 1 and 3 viruses in the vaccine. This phenomenon has also been found to be a problem with the dengue vaccines currently being researched, where the DEN-3 serotype was found to predominate and suppress the response to DEN-1, −2 and −4 serotypes.
6 Songs for Bruce 6 Songs for Bruce 6 Songs for Bruce, also commonly known as 4-Track Demo, is an early single-sided demo cassette tape by American rock band Soundgarden. The band, at the time a three-piece named Sound Garden, composed of guitarist Kim Thayil, bassist Hiro Yamamoto, and Chris Cornell on drums and vocals, recorded the demo in Jack Endino's basement four-track studio on April 24, 1985 for their friend Bruce Pavitt, hence the name of the tape, which features a rare early version of "Tears to Forget" sung by Yamamoto, and, as a bonus song, a Cornell's solo recording titled "The Storm".