Prodrug not its intended target. This reduces adverse or unintended effects of a drug, especially important in treatments like chemotherapy, which can have severe unintended and undesirable side effects. Many herbal extracts historically used in medicine contain glycosides (sugar derivatives) of the active agent, which are hydrolyzed in the intestines to release the active and more bioavailable aglycone. For example, salicin is a β-D-glucopyranoside that is cleaved by esterases to release salicylic acid. Aspirin, acetylsalicylic acid, first made by Felix Hoffmann at Bayer in 1897, is a synthetic prodrug of salicylic acid. However, in other cases, such as codeine and morphine,
Cupboard love love. The term ""cupboard-lover"" refers to someone who will only profess their love, or act endearingly for the sake of gain from another person. Cupboard love Cupboard love is a popular learning theory of the 1950s and 1960s based on the research of Sigmund Freud, Anna Freud, Melanie Klein and Mary Ainsworth. Rooted in psychoanalysis, the theory speculates that attachment develops in the early stages of infancy. This process involves the mother satisfying her infant's instinctual needs, exclusively. Cupboard love theorists conclude that during infancy, our primary drive is food which leads to a secondary drive for attachment. Sigmund Freud,