Polio vaccine polio and post-polio syndrome. In the United States, vaccine is administered along with the tetanus, diphtheria, and acellular pertussis vaccines (DTaP) and a pediatric dose of hepatitis B vaccine. In the UK, IPV is combined with tetanus, diphtheria, pertussis, and "Haemophilus influenzae" type b vaccines. OPV is an attenuated vaccine, produced by the passage of the virus through nonhuman cells at a subphysiological temperature, which produces spontaneous mutations in the viral genome. Oral polio vaccines were developed by several groups, one of which was led by Albert Sabin. Other groups, led by Hilary Koprowski and H.R. Cox, developed their own
Sabin Vaccine Institute Africa, and the Americas. Sabin is currently working on multiple vaccines for humans including vaccines for Hookworm infection ("Na"-GST-1, "Na"-APR-1), Schistosomiasis ("Sm"-TSP-2), Chagas disease ("Tc"24, TSA-1), Leishmaniasis ("Ld"-NH36, PdSP15), Severe acute respiratory syndrome (SARS)/Middle East respiratory syndrome (MERS) (Pan-β-CoVax), Soil-transmitted helminthiasis (STH), and Onchocerciasis (Ov-"103", Ov-"RAL-2"). In 2006, Sabin co-founded the Global Network for Neglected Tropical Diseases in order "to raise the awareness, political will and funding necessary to control and eliminate the most common NTDs." Through its work on NTDs, Sabin hopes to reduce poverty caused by these diseases as many of them have been shown to adversely affect