Acetyl group known as paracetamol), and acetylsalicylic acid (better known as aspirin). The introduction of an acetyl group into a molecule is called acetylation. In biological organisms, acetyl groups are commonly transferred from acetyl-CoA to other organic molecules. Acetyl-CoA is an intermediate both in the biological synthesis and in the breakdown of many organic molecules. Acetyl-CoA is also created during the second stage of cellular respiration, the Krebs Cycle, by the action of pyruvate dehydrogenase on pyruvic acid. Histones and other proteins are often modified by acetylation. For example, on the DNA level, histone acetylation by acetyltransferases (HATs) causes an expansion of
The Indian in the Cupboard have been multiple reprints in various formats, including movie tie-in editions. The publisher recommended reading level is age nine and up. All the books revolve around a young boy, Omri, discovering the powers of a magical cupboard that turns plastic toys into real, living beings, resulting in Omri befriending an 18th century Iroquois (Haudenosaunee) chief named Little Bear. As the series progresses, Omri and his friend Patrick learn more about the cupboard's powers, including its ability to transport people to and fro through history. The book was reviewed for "The New York Times" where it was called "the best novel