History of aspirin History of aspirin The history of aspirin (IUPAC name acetylsalicylic acid ) begins with its synthesis and manufacture in 1899. Before that, salicylic acid had been used medicinally since antiquity. Medicines made from willow and other salicylate-rich plants appear in clay tablets from ancient Sumer as well as the Ebers Papyrus from ancient Egypt. Hippocrates referred to their use of salicylic tea to reduce fevers around 400 BC, and were part of the pharmacopoeia of Western medicine in classical antiquity and the Middle Ages. Willow bark extract became recognized for its specific effects on fever, pain and inflammation in the
The Indian in the Cupboard the nurse in the cupboard and bring her to life. The nurse, called Matron, believing she has has dozed off while on duty, saves Little Bear's life. Matron also announces that Bright Stars is pregnant and the boys decide that it would be safer to keep Bright Stars with them until after the baby is born, rather than return her to her war-torn village. Patrick brings the cowboy Boone back to life through the cupboard in order to help Bright Stars care for Little Bear. Little Bear tells Boone about the troubles his people are suffering during their war with