Varicella (video game) Varicella (video game) Varicella is a 1999 work of interactive fiction by Adam Cadre, distributed in z-code format as freeware. It is set in an alternate history which features roughly modern technology mixed with Renaissance-style principalities and court politics. The characters of Varicella use contemporary language from their home in a Renaissance castle, continuing the contrast between old and new. The player character is Primo Varicella, palace minister in Piedmont, who has to get rid of several rivals for the regency following the death of the king. He was inspired by the Machiavellian protagonist of Profit, but given even more
Stargardt disease long-term prognosis for patients with Stargardt disease is widely variable and depends on the age of onset and genetic alleles. The majority of people will progress to legal blindness. Stargardt disease has no impact on general health and life expectancy is normal. Some patients, usually those with the late onset form, can maintain excellent visual acuities for extended periods, and are therefore able to perform tasks such as reading or driving. A 2017 prospective epidemiologic study which recruited 81 patients with STGD over 12 months reported an incidence of between 1 and 1.28 per 10 000 individuals. The median age