Terephthalic acid Terephthalic acid Terephthalic acid is an organic compound with formula CH(COH). This white solid is a commodity chemical, used principally as a precursor to the polyester PET, used to make clothing and plastic bottles. Several million tonnes are produced annually. The common name is derived from the turpentine-producing tree "Pistacia terebinthus" and phthalic acid. Terephthalic acid was first isolated (from turpentine) by the French chemist Amédée Cailliot (1805–1884) in 1846. Terephthalic acid became industrially important after World War II. Terephthalic acid was produced by oxidation of "p"-xylene with dilute nitric acid. Air oxidation of "p"-xylene gives "p"-toluic acid, which resists
Aristolochic acid Aristolochic acid Aristolochic acids () are a family of carcinogenic, mutagenic, and nephrotoxic phytochemicals commonly found in the flowering plant family Aristolochiaceae (birthworts). Aristolochic acid (AA) I is the most abundant one. The family Aristolochiaceae includes the genera "Aristolochia" and "Asarum" (wild ginger), which are commonly used in Chinese herbal medicine. Although these compounds are widely associated with kidney problems, liver and urothelial cancers, the use of AA-containing plants for medicinal purposes has a long history. The FDA has issued warnings regarding consumption of AA-containing supplements. Birthwort plants, and the aristolochic acids they contain, were quite common in ancient Greek