Acetyl group known as paracetamol), and acetylsalicylic acid (better known as aspirin). The introduction of an acetyl group into a molecule is called acetylation. In biological organisms, acetyl groups are commonly transferred from acetyl-CoA to other organic molecules. Acetyl-CoA is an intermediate both in the biological synthesis and in the breakdown of many organic molecules. Acetyl-CoA is also created during the second stage of cellular respiration, the Krebs Cycle, by the action of pyruvate dehydrogenase on pyruvic acid. Histones and other proteins are often modified by acetylation. For example, on the DNA level, histone acetylation by acetyltransferases (HATs) causes an expansion of
Pyrophosphoric acid it is difficult to recrystallise from the melt. In aqueous solution pyrophosphoric acid like all polyphosphoric acids hydrolyses and eventually an equilibrium is established between phosphoric acid pyrophosphoric acid and polyphosphoric acids. When highly diluted, an aqueous solution of pyrophosphoric acid contains only phosphoric acid. Pyrophosphoric acid is a medium strong inorganic acid. Anions, salts, and esters of pyrophosphoric acid are called pyrophosphates. While pyrophosporic acid is corrosive, it is not known to be otherwise toxic. The name pyrophosphoric acid was given by a "Mr. Clarke of Glasgow" in 1827 who is credited with its discovery following the heating to