Vaccine one of the vaccine components is more robust than the others and suppresses the growth and immune response to the other components. This phenomenon was first noted in the trivalent Sabin polio vaccine, where the amount of serotype 2 virus in the vaccine had to be reduced to stop it from interfering with the "take" of the serotype 1 and 3 viruses in the vaccine. This phenomenon has also been found to be a problem with the dengue vaccines currently being researched, where the DEN-3 serotype was found to predominate and suppress the response to DEN-1, −2 and −4 serotypes.
Albert Bruce-Joy and travelled to America twice in his life. Albert Bruce-Joy Albert Bruce-Joy (21 August 1842 – 22 July 1924) was an Irish sculptor working in England. His original surname was Joy but he became known under his hyphenated name Bruce-Joy later in life. He was the brother of the painter George W. Joy. Son of William Bruce Joy, MD, Bruce-Joy was born in Dublin but educated in Offenbach, Paris and at King's College London. He trained as a sculptor with John Henry Foley at the National Art Training School, South Kensington, and the Royal Academy Schools. He began exhibiting at