Acetyl group known as paracetamol), and acetylsalicylic acid (better known as aspirin). The introduction of an acetyl group into a molecule is called acetylation. In biological organisms, acetyl groups are commonly transferred from acetyl-CoA to other organic molecules. Acetyl-CoA is an intermediate both in the biological synthesis and in the breakdown of many organic molecules. Acetyl-CoA is also created during the second stage of cellular respiration, the Krebs Cycle, by the action of pyruvate dehydrogenase on pyruvic acid. Histones and other proteins are often modified by acetylation. For example, on the DNA level, histone acetylation by acetyltransferases (HATs) causes an expansion of
The Indian in the Cupboard (film) the cupboard and keep the Indian a secret. When Omri arrives home from school, he is upset to discover that the Indian has returned to its original toy form. When he goes to bed, Omri once more hears the tapping noise he heard that morning. He opens the cupboard to find the Indian alive once more. The Indian is again initially frightened of Omri but warms up to him, thinking Omri is a great spirit in a child's form, as the two begin talking, slowly forming a friendship. The Indian reveals himself as an English-speaking, 18th-century Iroquois Indian named Little