Varicella vaccine were vaccinated as children were still protected from varicella." However, since only one out of five Japanese children were vaccinated, the annual exposure of these vaccinees to children with natural chickenpox boosted the vaccinees' immune system. In the United States, where universal varicella vaccination has been practiced, the majority of children no longer receive exogenous (outside) boosting, thus, their cell-mediated immunity to VZV (varicella zoster virus) wanes—necessitating booster chickenpox vaccinations. As time goes on, boosters may be necessary. Persons exposed to the virus after vaccine tend to experience milder cases of chickenpox. Catching "wild" chickenpox as a child has been
Center for Disease Dynamics, Economics & Policy at the Center for Disease Dynamics, Economics & Policy (CDDEP), in Washington, DC and New Delhi, provides technical support to each working group, creates links within the GARP network and involves the working groups in global discussions and policy development. GARP is a CDDEP project, funded by the Bill & Melinda Gates Foundation. The Affordable Medicines Facility-malaria (AMFm) is an innovative financing mechanism designed to expand access to the most effective treatment for malaria, artemisinin-based combination therapies (ACTs) through the public, private and NGO sectors. It will reduce the use of drugs that no longer work because of drug resistance,