Polio vaccine polio and post-polio syndrome. In the United States, vaccine is administered along with the tetanus, diphtheria, and acellular pertussis vaccines (DTaP) and a pediatric dose of hepatitis B vaccine. In the UK, IPV is combined with tetanus, diphtheria, pertussis, and "Haemophilus influenzae" type b vaccines. OPV is an attenuated vaccine, produced by the passage of the virus through nonhuman cells at a subphysiological temperature, which produces spontaneous mutations in the viral genome. Oral polio vaccines were developed by several groups, one of which was led by Albert Sabin. Other groups, led by Hilary Koprowski and H.R. Cox, developed their own
Alvah Sabin Alvah Sabin Alvah Sabin (October 23, 1793 – January 22, 1885) was an American politician and clergyman. He served as a United States Representative from Vermont. Sabin was born in Georgia, Vermont to Benjamin Sabin and Polly McMaster Sabin, and was educated in the common schools. He was also a member of the Vermont militia and served during the War of 1812. Sabin also attended the University of Vermont in Burlington, which awarded him the honorary degree of master of arts in 1826. After the war, Sabin studied theology in Philadelphia and graduated from Columbian College (now George Washington University),