Varicella zoster virus the ACIP recommended a second dose of vaccine before school entry to ensure the maintenance of high levels of varicella immunity. In 2006, the United States Food and Drug Administration approved Zostavax for the prevention of shingles. Zostavax is a more concentrated formulation of the Varivax vaccine, designed to elicit an immune response in older adults whose immunity to VZV wanes with advancing age. A systematic review by the Cochrane Library shows that Zostavax reduces the incidence of shingles by almost 50%. Shingrix is a "V. zoster" vaccine developed by GlaxoSmithKline which was approved in the United States by the
Riggs' disease Riggs' disease Riggs' disease, also known as pyorrhea of a toothsocket or gingivitis expulsiva, is a historical term for periodontitis (gum disease), The condition was described as a purulent inflammation of the dental periosteum. It was named after American dentist John Mankey Riggs (1811–1885). Riggs' disease was said to produce the progressive necrosis of the alveoli and looseness of the teeth. The teeth may become very loose and fall out of the sockets. Mark Twain wrote briefly about Riggs' disease in his short essay, "Happy Memories of the Dental Chair", in which he claims to have been examined by Dr.