House of York Warwick himself changed sides, and supported Margaret of Anjou and the king's jealous brother George, Duke of Clarence, in briefly restoring Henry in 1470-71. However, Edward regained his throne, and the House of Lancaster was wiped out with the death of Henry VI himself, in the Tower of London in 1471. In 1478, the continued trouble caused by Clarence led to his execution in the Tower of London; popularly he is thought to have been drowned in a butt of malmsey wine. On Edward's death in 1483, the crown passed to his twelve-year-old son Edward. Edward IV's younger brother Richard,
Isabel Neville, Duchess of Clarence to England's heir presumptive, George Plantagenet, 1st Duke of Clarence, the brother of both King Edward IV and Richard, Duke of Gloucester (later Richard III). The king opposed the marriage as it would bring the already powerful Earl of Warwick too close to the throne. However the ceremony took place in secret at Calais on 11 July 1469, conducted by Isabel Neville's uncle George Neville, archbishop of York. Following their marriage Clarence joined forces with Warwick and allied with the Lancastrians led by Margaret of Anjou, queen consort to Henry VI. After Isabel Neville's sister Anne was married to Edward