Aspirin for its health effects for at least 2,400 years. In 1853, chemist Charles Frédéric Gerhardt treated the medicine sodium salicylate with acetyl chloride to produce acetylsalicylic acid for the first time. For the next fifty years, other chemists established the chemical structure and came up with more efficient methods to make it. In 1897, scientists at the Bayer company began studying acetylsalicylic acid as a less-irritating replacement medication for common salicylate medicines. By 1899, Bayer had named it "Aspirin" and sold it around the world. Aspirin's popularity grew over the first half of the twentieth century leading to competition between
The Indian in the Cupboard (film) successes like "Apollo 13", "Nine Months", "Pocahontas", and "Batman Forever". As a result, plans to adapt the next three books in the series into films were dropped. The Indian in the Cupboard (film) The Indian in the Cupboard is a 1995 American family fantasy drama film directed by Frank Oz and written by Melissa Mathison, based on the children's book of the same name by Lynne Reid Banks. The story is about a boy who receives a cupboard as a gift on his ninth birthday. He later discovers that putting toy figures in the cupboard, after locking and unlocking it,