Acetyl group known as paracetamol), and acetylsalicylic acid (better known as aspirin). The introduction of an acetyl group into a molecule is called acetylation. In biological organisms, acetyl groups are commonly transferred from acetyl-CoA to other organic molecules. Acetyl-CoA is an intermediate both in the biological synthesis and in the breakdown of many organic molecules. Acetyl-CoA is also created during the second stage of cellular respiration, the Krebs Cycle, by the action of pyruvate dehydrogenase on pyruvic acid. Histones and other proteins are often modified by acetylation. For example, on the DNA level, histone acetylation by acetyltransferases (HATs) causes an expansion of
The Indian in the Cupboard the Iroquois and Boone. Omri uses the trunk to bring Patrick back to the present and at the same time return the Iroquois to the past, but returning Patrick inadvertently drags the tornado back to Omri's room, destroying part of the house and neighborhood. In the chaos, the cupboard is damaged and the key lost. Omri's headmaster, who has been lurking outside the house hoping to catch evidence of Omri's secret, is struck on the head by debris, meaning that no one believes any of his ramblings about "tiny people." Boone and Ruby Lou realize they are stranded as tiny