Aspirin for its health effects for at least 2,400 years. In 1853, chemist Charles Frédéric Gerhardt treated the medicine sodium salicylate with acetyl chloride to produce acetylsalicylic acid for the first time. For the next fifty years, other chemists established the chemical structure and came up with more efficient methods to make it. In 1897, scientists at the Bayer company began studying acetylsalicylic acid as a less-irritating replacement medication for common salicylate medicines. By 1899, Bayer had named it "Aspirin" and sold it around the world. Aspirin's popularity grew over the first half of the twentieth century leading to competition between
The Indian in the Cupboard year", "The Indian in the Cupboard" has received several literary awards across the years and is becoming regarded as a classic in children's literature. A list of the awards received is as follows: Because of the varying opinions on the subject matter and portrayal of Native Americans in the novel, the quality of the book is largely subjective. While it can be argued that the stereotypes perpetuated by the novel are unforgivable, advocates for book praise the novel on aspects of convincing characters, reader captivation and enchantment, and keeping in touch with young readers, among other things. The second book