Polio vaccine attenuated vaccine strains. In 1958, the National Institutes of Health created a special committee on live polio vaccines. The various vaccines were carefully evaluated for their ability to induce immunity to polio, while retaining a low incidence of neuropathogenicity in monkeys. Large-scale clinical trials performed in the Soviet Union in late 1950s to early 1960s by Mikhail Chumakov and his colleagues demonstrated safety and high efficacy of the vaccine. Based on these results, the Sabin strains were chosen for worldwide distribution. Fifty-seven nucleotide substitutions distinguish the attenuated Sabin 1 strain from its virulent parent (the Mahoney serotype), two nucleotide substitutions
His Name Is Legs (Ladies and Gentlemen) including "Time Bandits" (1981), "The Missionary" (1982), "A Private Function" (1984) and "Nuns on the Run" (1990). Leng recognises an increasing Python-based comedy influence in Harrison's songwriting and musical arrangements, beginning with his 1979 track "Soft-Hearted Hana" and subsequently including "Save the World", with that song's "groove … horn charts and moog riffs" reminiscent of "His Name Is Legs", and "Greece". Following his guest appearance on "His Name Is Legs", Smith became part of a coterie of local musicians known as the Henley Music Mafia, which also included Harrison, Alvin Lee, Jon Lord and Joe Brown. Smith appeared in the