Varicella zoster virus and safe in adults with Human Immunodeficiency Virus. Chickenpox-like rashes were recognised and described by ancient civilizations; the relationship between zoster and chickenpox was not realized until 1888. It was in 1943 that Ruska noticed the similarity between virus particles isolated from the lesions of zoster and those from chickenpox. In 1974 the first vaccine was introduced for chickenpox. Varicella zoster virus Varicella zoster virus or varicella-zoster virus (VZV) is one of eight herpesviruses known to infect humans. It causes chickenpox (varicella), a disease most commonly affecting children, teens, and young adults, and shingles (herpes zoster) in adults; shingles is
Paget's disease of bone involve an inflammatory process, which is implied by the suffix "-itis". Now, that term is considered technically incorrect, and the preferred term is osteodystrophia deformans. Paget's disease of bone Paget's disease of bone (commonly known as Paget's disease or historically, osteitis deformans) is a condition involving cellular remodeling and deformity of one or more bones. The affected bones show signs of dysregulated bone remodeling at the microscopic level, specifically excessive bone breakdown and subsequent disorganized new bone formation. These structural changes cause the bone to weaken, which may result in deformity, pain, fracture, or arthritis of associated joints. The exact