Acetyl group known as paracetamol), and acetylsalicylic acid (better known as aspirin). The introduction of an acetyl group into a molecule is called acetylation. In biological organisms, acetyl groups are commonly transferred from acetyl-CoA to other organic molecules. Acetyl-CoA is an intermediate both in the biological synthesis and in the breakdown of many organic molecules. Acetyl-CoA is also created during the second stage of cellular respiration, the Krebs Cycle, by the action of pyruvate dehydrogenase on pyruvic acid. Histones and other proteins are often modified by acetylation. For example, on the DNA level, histone acetylation by acetyltransferases (HATs) causes an expansion of
The Indian in the Cupboard The Indian in the Cupboard The Indian in the Cupboard is a low fantasy children's novel by the British writer Lynne Reid Banks, published in 1980 with illustrations by Robin Jacques (UK) and Brock Cole (US). It was later adapted as a 1995 children's film under the same name. The original book was followed by four sequels: "The Return of the Indian" (1985); "The Secret of the Indian" (1989); "The Mystery of the Cupboard" (1993); and "The Key to the Indian" (1998). All were published by Doubleday Books in hardcover, then by Avon Books, now Harper Collins, in paperback. There