Aspirin for its health effects for at least 2,400 years. In 1853, chemist Charles Frédéric Gerhardt treated the medicine sodium salicylate with acetyl chloride to produce acetylsalicylic acid for the first time. For the next fifty years, other chemists established the chemical structure and came up with more efficient methods to make it. In 1897, scientists at the Bayer company began studying acetylsalicylic acid as a less-irritating replacement medication for common salicylate medicines. By 1899, Bayer had named it "Aspirin" and sold it around the world. Aspirin's popularity grew over the first half of the twentieth century leading to competition between
The Indian in the Cupboard have been multiple reprints in various formats, including movie tie-in editions. The publisher recommended reading level is age nine and up. All the books revolve around a young boy, Omri, discovering the powers of a magical cupboard that turns plastic toys into real, living beings, resulting in Omri befriending an 18th century Iroquois (Haudenosaunee) chief named Little Bear. As the series progresses, Omri and his friend Patrick learn more about the cupboard's powers, including its ability to transport people to and fro through history. The book was reviewed for "The New York Times" where it was called "the best novel