Hepatic stellate cell A decreases progressively in liver injury. The activated stellate cell is also responsible for secreting collagen scar tissue, which can lead to cirrhosis. More recent studies have also shown that in vivo activation of hepatic stellate cells by agents causing liver fibrosis can eventually lead to senescence in these cells, marked by increased SA-beta-galactosidase staining, as well as p53 accumulation and activation of Rb–hallmarks of cellular senescence. Senescent hepatic stellate cells have been demonstrated to limit liver fibrosis by activating interactions with NK cells. The cells of Ito were named for Toshio Ito, a twentieth-century Japanese physician, who introduced a
The Neck Is a Bridge to the Body The Neck Is a Bridge to the Body The Neck Is a Bridge to the Body, is the Eighth full-length album by American guitarist Kaki King, released March 3, 2015. The album is the soundtrack to Kaki's projection mapping show of the same name. In 2014, Kaki collaborated with the visual experience company Glowing Pictures to construct an innovative, immersive multi-media production in which the guitar is used as a projection screen to tell a story. The hour-long production, entitled The Neck is a Bridge to the Body, places the focus on the guitar itself, the Instrument serving as an