Prairie dog and Clark in 1804. Lewis described it in more detail in 1806, calling it the "barking squirrel". On average, these stout-bodied rodents will grow to be between long, including the short tail, and weigh between . Sexual dimorphism in body mass in the prairie dog varies 105 to 136% between the sexes. Among the species, black-tailed prairie dogs tend to be the least sexually dimorphic, and white-tailed prairie dogs tend to be the most sexually dimorphic. Sexual dimorphism peaks during weaning, when the females lose weight and the males start eating more, and is at its lowest when the females
Black-tailed prairie dog may increase mortality. Roads, streams, and lakes may serve as barriers to sylvatic plague. Black-tailed prairie dogs are frequently exterminated from ranchland, being viewed as pests. Their habitat has been fragmented, and their numbers have been greatly reduced. Additionally, they are remarkably susceptible to plague. In 2006, all eight appearances of plague in black-tailed prairie dog colonies resulted in total colony loss. Studies in 1961 estimated only of occupied black-tailed prairie dog habitat in the United States. A second study in 2000 showed . However, a comprehensive study between 10 states and various tribes in 2004 estimated in the United