Hepatic veno-occlusive disease Hepatic veno-occlusive disease Hepatic veno-occlusive disease or veno-occlusive disease with immunodeficiency (VODI) is a condition in which some of the small veins in the liver are obstructed. It is a complication of high-dose chemotherapy given before a bone marrow transplant (BMT) and is marked by weight gain due to fluid retention, increased liver size, and raised levels of bilirubin in the blood. The name sinusoidal obstruction syndrome is now preferred if VODI happens as a result of chemotherapy or bone marrow transplantation. Apart from chemotherapy, VODI may also occur after ingestion of certain plant alkaloids such as pyrrolizidine alkaloids (in
British Institute of Organ Studies British Institute of Organ Studies The British Institute of Organ Studies, more commonly known by its acronym BIOS, is a British organisation and registered charity which aims to promote study and appreciation of all aspects of the pipe organ. Further, it acts as a lobbying body to raise awareness of organ issues with appropriate statutory bodies. Membership is open to all. The aims of BIOS are BIOS publishes a quarterly Reporter newsletter and magazine and a yearly Journal which contains articles on organ history. BIOS is also responsible for the National Pipe Organ Register (NPOR), which aims to catalogue all