Vitamin C megadosage systemic conditioning ("rebound scurvy"), preoxidant effects, iron overload, reduced absorption of vitamin B12 and copper, increased oxygen demand, and acid erosion of the teeth with chewing ascorbic-acid tablets. In addition, one case has been noted of a woman who had received a kidney transplant followed by high-dose vitamin C and died soon afterwards as a result of calcium oxalate deposits that destroyed her new kidney. Her doctors concluded that high-dose vitamin C therapy should be avoided in patients with renal failure. As discussed previously, vitamin C generally exhibits low toxicity. The (the dose that will kill 50% of a population)
History of the United States Navy ended by the Treaty of Paris in 1783, and by 1785 the Continental Navy was disbanded and the remaining ships were sold. The frigate , which had fired the last shots of the American Revolutionary War, was also the last ship in the Navy. A faction within Congress wanted to keep the ship, but the new nation did not have the funds to keep her in service. Other than a general lack of money, factors for the disarmament of the navy were the loose confederation of the states, a change of goals from war to peace, and more domestic and