Hepatic encephalopathy treatment may benefit people with hepatic encephalopathy. LOLA lowers ammonia levels by increasing the generation of urea through the urea cycle, a metabolic pathway that removes ammonia by turning it into the neutral substance urea. LOLA may be combined with lactulose and/or rifaximin if these alone are ineffective at controlling symptoms. In those with cirrhosis, the risk of developing hepatic encephalopathy is 20% per year, and at any time about 30–45% of people with cirrhosis exhibit evidence of overt encephalopathy. The prevalence of minimal hepatic encephalopathy detectable on formal neuropsychological testing is 60–80%; this increases the likelihood of developing overt
Adjective in context. Determiners generally do this by indicating definiteness (as in "a" vs. "the"), quantity (as in "one" vs. "some" vs. "many"), or another such property. An adjective acts as the head of an "adjective phrase" or "adjectival phrase" (AP). In the simplest case, an adjective phrase consists solely of the adjective; more complex adjective phrases may contain one or more adverbs modifying the adjective (""very" strong"), or one or more complements (such as "worth "several dollars"", "full "of toys"", or "eager "to please""). In English, attributive adjective phrases that include complements typically follow the noun that they qualify ("an