Vitamin C symptoms are malaise and lethargy, progressing to shortness of breath, bone pain, bleeding gums, susceptibility to bruising, poor wound healing, and finally fever, convulsions and eventual death. Until quite late in the disease the damage is reversible, as healthy collagen replaces the defective collagen with vitamin C repletion. Treatment can be orally or by intramuscular or intravenous injection. Scurvy was known to Hippocrates in the classical era. The disease was shown to be prevented by citrus fruit in an early controlled trial by a Royal Navy surgeon, James Lind, in 1747, and from 1796 lemon juice was issued to all
In the Days of the Comet he had been a great success at the university." Leadford's only close friend is a fellow clerk and socialist. But the pair quarrel and Leadford breaks off relations when Parload avers that socialism is "only a theory," whereas science is "something more". In later years Parload becomes a great scientist whose "work upon intersecting radiations has broadened the intellectual horizon of mankind for ever." Wells's open endorsement of polyamorous love at the end of "In the Days of the Comet" caused some scandal. Various organisations dedicated to preserving public morals, including the YWCA, Salvation Army and ‘Anti-Vice and White Slavery’