Vitamin C and the common cold but it has halved the frequency of colds in people under heavy short-term physical stress. There is no effect of taking vitamin C in doses up to 8 grams per day after a cold has already begun. Vitamin C was identified in the early part of the twentieth century, and there was much interest in its possible effects on various infections including the common cold. A few controlled trials on the effect of vitamin C on the common cold were carried out already in the 1940s, the earliest of these appears to be a placebo-controlled trial published in 1945. The
Scurvy and laced with spices. In 1764, a new variant appeared. Advocated by Dr David MacBride and Sir John Pringle, Surgeon General of the Army and later President of the Royal Society, this idea was that scurvy was the result of a lack of 'fixed air' in the tissues which could be prevented by drinking infusions of malt and wort whose fermentation within the body would stimulate digestion and restore the missing gases. These ideas received wide and influential backing, when James Cook set off to circumnavigate the world (1768–1771) in , malt and wort were top of the list of