Hepatic encephalopathy treatment may benefit people with hepatic encephalopathy. LOLA lowers ammonia levels by increasing the generation of urea through the urea cycle, a metabolic pathway that removes ammonia by turning it into the neutral substance urea. LOLA may be combined with lactulose and/or rifaximin if these alone are ineffective at controlling symptoms. In those with cirrhosis, the risk of developing hepatic encephalopathy is 20% per year, and at any time about 30–45% of people with cirrhosis exhibit evidence of overt encephalopathy. The prevalence of minimal hepatic encephalopathy detectable on formal neuropsychological testing is 60–80%; this increases the likelihood of developing overt
Postpositive adjective Postpositive adjective A postpositive or postnominal adjective is an attributive adjective that is placed after the noun or pronoun that it modifies. This contrasts with prepositive adjectives, which come before the noun or pronoun. In some languages the postpositive placement of adjectives is the normal syntax, but in English it is less usual, largely confined to archaic and poetic uses (as in "They heard wights unseen), phrases loaned from Romance languages or Latin (such as "heir apparent, "aqua regia"), and certain particular grammatical constructions (as in "those anxious to leave"). Recognizing postpositive adjectives in English is important for determining the