Hepatic lipase often found bound to HSPG, heparan sulfate proteoglycans (HSPG), keeping HL inactive and unable to bind to HDL (high density lipoprotein) or IDL (intermediate density lipoprotein). When it is free in the bloodstream, however, it is found associated with HDL to maintain it inactive. This is because the triacylglycerides in HDL serve as a substrate, but the lipoprotein contains proteins around the triacylglycerides that can prevent the triacylglycerides from being broken down by HL. One of the principal functions of hepatic lipase is to convert intermediate-density lipoprotein (IDL) to low-density lipoprotein (LDL). Hepatic lipase thus plays an important role in
Proper adjective adjectives. In general, an adjective is capitalized if its meaning is "pertaining to "X"", where "X" is some specific person, place, language, or organized group. Most capitalized adjectives are derived from proper nouns; for example, the proper adjective "American" is derived from the proper noun "America". Sometimes, an adjective is capitalized because it designates an ethnic group with a shared culture, heritage, or ancestry. This usage asserts the existence of a unified group with common goals. For example, in Canadian government documents, "Native" and "Aboriginal" are capitalized. An adjective can lose its capitalization when it takes on new meanings, such