Vitamin and C dissolve into the water when a vegetable is boiled, and are then lost when the water is discarded. The body's stores for different vitamins vary widely; vitamins A, D, and B are stored in significant amounts, mainly in the liver, and an adult's diet may be deficient in vitamins A and D for many months and B in some cases for years, before developing a deficiency condition. However, vitamin B (niacin and niacinamide) is not stored in significant amounts, so stores may last only a couple of weeks. For vitamin C, the first symptoms of scurvy in experimental
Scurvy cured scurvy before any fatalities occurred. In 1907, an animal model which would eventually help to isolate and identify the "antiscorbutic factor" was discovered. Axel Holst and Theodor Frølich, two Norwegian physicians studying shipboard beriberi contracted by ship's crews in the Norwegian Fishing Fleet, wanted a small test mammal to substitute for the pigeons then used in beriberi research. They fed guinea pigs their test diet of grains and flour, which had earlier produced beriberi in their pigeons, and were surprised when classic scurvy resulted instead. This was a serendipitous choice of animal. Until that time, scurvy had not been