Congenital hepatic fibrosis Congenital hepatic fibrosis Congenital hepatic fibrosis is an inherited fibrocystic liver disease associated with proliferation of interlobular bile ducts within the portal areas and fibrosis that do not alter hepatic lobular architecture. The fibrosis would affect resistance in portal veins leading to portal hypertension. The condition is usually congenital, but sporadic cases have also been reported. It may be associated with other congenital defects, commonly with autosomal recessive polycystic kidney disease, the most severe form of PKD. Some suggest that these two conditions are one disorder with different presentation. Embryogenically, congenital hepatic fibrosis is due to malformation of the duct
Adjective in context. Determiners generally do this by indicating definiteness (as in "a" vs. "the"), quantity (as in "one" vs. "some" vs. "many"), or another such property. An adjective acts as the head of an "adjective phrase" or "adjectival phrase" (AP). In the simplest case, an adjective phrase consists solely of the adjective; more complex adjective phrases may contain one or more adverbs modifying the adjective (""very" strong"), or one or more complements (such as "worth "several dollars"", "full "of toys"", or "eager "to please""). In English, attributive adjective phrases that include complements typically follow the noun that they qualify ("an