Hepatic encephalopathy treatment may benefit people with hepatic encephalopathy. LOLA lowers ammonia levels by increasing the generation of urea through the urea cycle, a metabolic pathway that removes ammonia by turning it into the neutral substance urea. LOLA may be combined with lactulose and/or rifaximin if these alone are ineffective at controlling symptoms. In those with cirrhosis, the risk of developing hepatic encephalopathy is 20% per year, and at any time about 30–45% of people with cirrhosis exhibit evidence of overt encephalopathy. The prevalence of minimal hepatic encephalopathy detectable on formal neuropsychological testing is 60–80%; this increases the likelihood of developing overt
Adjective phrase Adjective phrase An adjective phrase (or adjectival phrase) is a phrase the head word of which is an adjective, e.g. "fond of steak", "very happy", "quite upset about it", etc. The adjective can initiate the phrase (e.g. "fond of steak"), conclude the phrase (e.g. "very happy"), or appear in a medial position (e.g. "quite upset about it"). The dependents of the head adjective—i.e. the other words and phrases inside the adjective phrase—are typically adverb or prepositional phrases, but they can also be clauses (e.g. "louder than you are"). Adjectives and adjective phrases function in two basic ways, attributively or predicatively.