Brenner, South Tyrol Valentine" church, the "Post Hotel" and few other houses on the south side, the "Kerschbaumer Hotel", "Griesberg" and "Venn" on the north, nowadays in Austria. The old carriage was enlarged and the tracing modified in 1740 in order to have a comfortable road; Goethe, on 8 September 1786, on his journey to Italy stopped in Brenner at "Post Hotel". The construction of the Brenner railway, between Innsbruck and Bolzano through the Brenner Pass, began on 23 February 1864 at Bergisel (Innsbruck) and the building involved the village with hundreds of workers who lived there for three years. The railway transformed
Sydney Brenner concept of a messenger RNA, based on correctly interpreting the work of Elliot "Ken" Volkin and Larry Astrachan. Then, with Francis Crick, Leslie Barnett and Richard J. Watts-Tobin, Brenner genetically demonstrated the triplet nature of the code of protein translation through the Crick, Brenner, Barnett, Watts-Tobin et al. experiment of 1961, which discovered frameshift mutations. This insight provided early elucidation of the nature of the genetic code. Leslie Barnett helped set up Sydney Brenner's laboratory in Singapore, many years later. Brenner, with George Pieczenik, created the first computer matrix analysis of nucleic acids using TRAC, which Brenner continues to use.