Vitamin C contributing to the more severe symptoms of scurvy. More generally, the biochemical role of vitamin C is to act as an antioxidant (a reducing agent) by donating electrons to various enzymatic and non-enzymatic reactions. Doing so converts vitamin C to an oxidized state - either as semidehydroascorbic acid or dehydroascorbic acid. These compounds can be restored to a reduced state by glutathione and NADPH-dependent enzymatic mechanisms. In plants, vitamin C is a substrate for ascorbate peroxidase. This enzyme utilizes ascorbate to neutralize toxic hydrogen peroxide (HO) by converting it to water (HO). Scurvy is a disease resulting from a deficiency
History of electroconvulsive therapy in the United States better term, shocking. “In these early days clients might be ‘shocked’ in open, communal wards of psychiatric asylums, tied to beds, without anaesthetic or muscle-relaxing agents, often several times a week. As an unfortunate consequence, many of the patients who underwent ECT felt abused, oppressed, punished and damaged, all of which had a negative impact on the treatment itself and psychiatry as a whole”. “Aside from the therapy’s crude beginnings, controversy may have also been caused by a lack of information given when practitioners obtain informed consent before treatment, unknown mechanism of action, lack of knowledge about the cognitive adverse