Hepatic stellate cell A decreases progressively in liver injury. The activated stellate cell is also responsible for secreting collagen scar tissue, which can lead to cirrhosis. More recent studies have also shown that in vivo activation of hepatic stellate cells by agents causing liver fibrosis can eventually lead to senescence in these cells, marked by increased SA-beta-galactosidase staining, as well as p53 accumulation and activation of Rb–hallmarks of cellular senescence. Senescent hepatic stellate cells have been demonstrated to limit liver fibrosis by activating interactions with NK cells. The cells of Ito were named for Toshio Ito, a twentieth-century Japanese physician, who introduced a
Adjective phrase to post-nominal position, only one interpretation is possible. There is cross-linguistic validity, according to the multiple articles referenced in Cinque's article, which studied this adjective placement in Italian as well. Cinque discovered that exactly the same pattern was seen in Italian, because ambiguous interpretations only appeared when the adjective phrase was placed in pre-nominal position. Next, other research articles also confirm that this word order phenomenon exists in Mandarin Chinese, creating ambiguous interpretations. For example, an adjective phrase with the head adjective "private" in pre-object position, creates two interpretations. On the other hand, an adjective phrase with the head adjective