What Is Life? published in 1944. At that time DNA was not yet accepted as the carrier of hereditary information, which only was the case after the Hershey–Chase experiment of 1952. One of the most successful branches of physics at this time was statistical physics, and quantum mechanics, a theory which is also very statistical in its nature. Schrödinger himself is one of the founding fathers of quantum mechanics. Max Delbrück's thinking about the physical basis of life was an important influence on Schrödinger. However, long before the publication of "What is Life?", geneticist and 1946 Nobel-prize winner H. J. Muller had in
Physical modelling synthesis Physical modelling synthesis Physical modelling synthesis refers to sound synthesis methods in which the waveform of the sound to be generated is computed using a mathematical model, a set of equations and algorithms to simulate a physical source of sound, usually a musical instrument. Modelling attempts to replicate laws of physics that govern sound production, and will typically have several parameters, some of which are constants that describe the physical materials and dimensions of the instrument, while others are time-dependent functions describing the player's interaction with the instrument, such as plucking a string, or covering toneholes. For example, to model