Vitamin C symptoms are malaise and lethargy, progressing to shortness of breath, bone pain, bleeding gums, susceptibility to bruising, poor wound healing, and finally fever, convulsions and eventual death. Until quite late in the disease the damage is reversible, as healthy collagen replaces the defective collagen with vitamin C repletion. Treatment can be orally or by intramuscular or intravenous injection. Scurvy was known to Hippocrates in the classical era. The disease was shown to be prevented by citrus fruit in an early controlled trial by a Royal Navy surgeon, James Lind, in 1747, and from 1796 lemon juice was issued to all
Names of the days of the week nundinal cycle with the seven-day week. Our earliest evidence for this new system is a Pompeiian graffito referring to the 6th February ("viii idus Februarius") of the year AD 60 as "dies solis" ("Sunday"). Another early witness is a reference to a lost treatise by Plutarch, written in about AD 100, which addressed the question of "Why are the days named after the planets reckoned in a different order from the actual order?". The days were named after the planets of Hellenistic astrology, in the order Sun, Moon, Mars ("Ares"), Mercury ("Hermes"), Jupiter ("Zeus"), Venus ("Aphrodite") and Saturn ("Cronos"). The