Vitamin C megadosage the airways as a result of vigorous exercise. EIB seems to be caused by the loss of water caused by increased ventilation, which may lead to the release of mediators such as histamine, prostaglandins and leukotrienes, all of which cause bronchoconstriction. Vitamin C participates in the metabolism of these mediators and might thereby influence EIB. A meta-analysis showed that 0.5 to 2 g/day of vitamin C before exercise decreased EIB by half. A meta-analysis showed a significant positive effect of vitamin C on endothelial function. Benefit was found of vitamin C in doses in the range from 0.5 to 4
History of electroconvulsive therapy in the United States better term, shocking. “In these early days clients might be ‘shocked’ in open, communal wards of psychiatric asylums, tied to beds, without anaesthetic or muscle-relaxing agents, often several times a week. As an unfortunate consequence, many of the patients who underwent ECT felt abused, oppressed, punished and damaged, all of which had a negative impact on the treatment itself and psychiatry as a whole”. “Aside from the therapy’s crude beginnings, controversy may have also been caused by a lack of information given when practitioners obtain informed consent before treatment, unknown mechanism of action, lack of knowledge about the cognitive adverse