Vitamin C contributing to the more severe symptoms of scurvy. More generally, the biochemical role of vitamin C is to act as an antioxidant (a reducing agent) by donating electrons to various enzymatic and non-enzymatic reactions. Doing so converts vitamin C to an oxidized state - either as semidehydroascorbic acid or dehydroascorbic acid. These compounds can be restored to a reduced state by glutathione and NADPH-dependent enzymatic mechanisms. In plants, vitamin C is a substrate for ascorbate peroxidase. This enzyme utilizes ascorbate to neutralize toxic hydrogen peroxide (HO) by converting it to water (HO). Scurvy is a disease resulting from a deficiency
History of medicine in the Philippines surveyors of herbal medicines at the localities where they were assigned. Common disease during the Spanish period in the Philippines were diarrhea, dysentery, and leprosy. There were also the presence of cholera, inﬂuenza, smallpox, beri-beri, dysentery, bubonic plague, scurvy, rheumatism, asthma, syphilis, tetanus, toothache, and ulcers. Many Filipinos believed in "pasma" (a resulting condition similar to spasm which involves the occurrence of hand tremors, sweaty palms, numbness and pains after the body's exposure to "unhealthy cold" and water), the state of "nausog" ("distress" caused by an unfamiliar person), and "personalistic sorcery". It was in 1830 when the "true pharmacies" were