Hepatic encephalopathy treatment may benefit people with hepatic encephalopathy. LOLA lowers ammonia levels by increasing the generation of urea through the urea cycle, a metabolic pathway that removes ammonia by turning it into the neutral substance urea. LOLA may be combined with lactulose and/or rifaximin if these alone are ineffective at controlling symptoms. In those with cirrhosis, the risk of developing hepatic encephalopathy is 20% per year, and at any time about 30–45% of people with cirrhosis exhibit evidence of overt encephalopathy. The prevalence of minimal hepatic encephalopathy detectable on formal neuropsychological testing is 60–80%; this increases the likelihood of developing overt
Nominalized adjective elaborated by Noam Chomsky, it is suggested that inflected adjectives are more likely to be nominalized because they have overtly-marked φ-features (such as grammatical number and gender), which makes them suitable for use as the complement of a determiner. Determiners with unvalued φ-features must find a complement with a valued φ-feature to meet semantic comprehension. In the diagrams below, the determiner is "the", and its complement is either the noun phrase "poor people" or the nominalized adjective "poor". As the frequency of nominalized adjective use decreased, the frequency of structures using the prop-word "one" increased (phrases such as "the large"