Hepatic encephalopathy treatment may benefit people with hepatic encephalopathy. LOLA lowers ammonia levels by increasing the generation of urea through the urea cycle, a metabolic pathway that removes ammonia by turning it into the neutral substance urea. LOLA may be combined with lactulose and/or rifaximin if these alone are ineffective at controlling symptoms. In those with cirrhosis, the risk of developing hepatic encephalopathy is 20% per year, and at any time about 30–45% of people with cirrhosis exhibit evidence of overt encephalopathy. The prevalence of minimal hepatic encephalopathy detectable on formal neuropsychological testing is 60–80%; this increases the likelihood of developing overt
Your Body Is a Wonderland Bernard sing the song as a karaoke duet. Mayer agreed to let the show use the song, in exchange for a Dundie, which was for "Tallest Music Dude". In the episode of Family Guy titled "Stew-Roids", Stewie sings a song in which he pronounces the word "body" like "bah-dy", which he then explains "That's how John Mayer would say it"; a reference to the pronunciation of the word in "Your Body Is a Wonderland". Lance Bass and Lacey Schwimmer performed a rhumba to the song on Season 7 of "Dancing with the Stars". Your Body Is a Wonderland "Your Body