Brenner Autobahn Eastern Alps; this favourable location was therefore suitable for building the first motorway crossing among the Alpine main chains. Unlike other higher passes across the Alps, the Brenner Pass remains open all-year round and through the winter months. Construction of the motorway began in 1959 and the "Brenner Autobahn", including the Bridge of Europe (Europe's highest motorway bridge then), was partially open in 1963. The A13 begins in the south of Innsbruck from the east-west motorway A12 Inntal Autobahn ("Inn Valley Motorway"), which links Bregenz in western Austria to Kufstein near the border of Bavaria in Germany. At above sea,
Sydney Brenner concept of a messenger RNA, based on correctly interpreting the work of Elliot "Ken" Volkin and Larry Astrachan. Then, with Francis Crick, Leslie Barnett and Richard J. Watts-Tobin, Brenner genetically demonstrated the triplet nature of the code of protein translation through the Crick, Brenner, Barnett, Watts-Tobin et al. experiment of 1961, which discovered frameshift mutations. This insight provided early elucidation of the nature of the genetic code. Leslie Barnett helped set up Sydney Brenner's laboratory in Singapore, many years later. Brenner, with George Pieczenik, created the first computer matrix analysis of nucleic acids using TRAC, which Brenner continues to use.