Percutaneous hepatic perfusion Percutaneous hepatic perfusion Percutaneous hepatic perfusion (PHP) is a regionalized, minimally-invasive approach to cancer treatment currently undergoing Phase II and Phase III clinical testing. PHP treats a variety of hepatic tumors by isolating the liver and exposing the organ to high-dose chemotherapy. As demonstrated in clinical trials, patients treated by PHP can tolerate much higher doses of chemotherapeutic agents than those receiving traditional systemic chemotherapy without increased toxicities. Using a system of catheters and filters, PHP isolates the liver from the circulatory system and infuses a chemotherapeutic agent directly to the liver via the hepatic artery. The venous effluent from
Nominalized adjective Nominalized adjective A nominalized adjective is an adjective that has undergone nominalization, and is thus used as a noun. For example, in "the rich and the poor", the adjectives "rich" and "poor" function as nouns denoting people who are rich and poor respectively. The most common appearance of the nominalized adjective in English is when an adjective is used to indicate a collective group. This happens in the case where a phrase such as "the poor people" becomes "the poor". The adjective "poor" is nominalized, and the noun "people" disappears. Other adjectives commonly used in this way include "rich", "wealthy",