Hepatic lipase released into the bloodstream. Another lipoprotein, ApoA-I, which increases release of HDL was shown to have a similar effect by mutating the gene that coded it. Mutated ApoA-I protein caused a decrease in HL release and thus decreased the amount of HL bound to HDL and released into the bloodstream. Hepatic lipase deficiency is a rare, autosomal recessive disorder that results in elevated high density lipoprotein (HDL) cholesterol due to a mutation in the hepatic lipase gene. Clinical features are not well understood and there are no characteristic xanthomas. There is an association with a delay in atherosclerosis in an
Spermaceti organ Spermaceti organ The spermaceti organ is an organ that commonly appears in the heads of toothed whales of the family Physeteroidea, in particular the sperm whale. This organ contains a waxy liquid called spermaceti and is involved in the generation of sound. In the modern day Great Sperm Whale ("Physeter macrocephalus"), the spermaceti organ is far larger in proportion to the animal’s body than what would be explained by simple allometry, and the evolution of the organ has caused changes in basal skull morphology, which may implicate tradeoffs were made that compromised the functionality of other nearby features. The high