Congenital hepatic fibrosis Congenital hepatic fibrosis Congenital hepatic fibrosis is an inherited fibrocystic liver disease associated with proliferation of interlobular bile ducts within the portal areas and fibrosis that do not alter hepatic lobular architecture. The fibrosis would affect resistance in portal veins leading to portal hypertension. The condition is usually congenital, but sporadic cases have also been reported. It may be associated with other congenital defects, commonly with autosomal recessive polycystic kidney disease, the most severe form of PKD. Some suggest that these two conditions are one disorder with different presentation. Embryogenically, congenital hepatic fibrosis is due to malformation of the duct
Nominalized adjective Nominalized adjective A nominalized adjective is an adjective that has undergone nominalization, and is thus used as a noun. For example, in "the rich and the poor", the adjectives "rich" and "poor" function as nouns denoting people who are rich and poor respectively. The most common appearance of the nominalized adjective in English is when an adjective is used to indicate a collective group. This happens in the case where a phrase such as "the poor people" becomes "the poor". The adjective "poor" is nominalized, and the noun "people" disappears. Other adjectives commonly used in this way include "rich", "wealthy",