Hepatic encephalopathy treatment may benefit people with hepatic encephalopathy. LOLA lowers ammonia levels by increasing the generation of urea through the urea cycle, a metabolic pathway that removes ammonia by turning it into the neutral substance urea. LOLA may be combined with lactulose and/or rifaximin if these alone are ineffective at controlling symptoms. In those with cirrhosis, the risk of developing hepatic encephalopathy is 20% per year, and at any time about 30–45% of people with cirrhosis exhibit evidence of overt encephalopathy. The prevalence of minimal hepatic encephalopathy detectable on formal neuropsychological testing is 60–80%; this increases the likelihood of developing overt
Adjective phrase English is that an attributive adjective alone generally precedes the noun, e.g. "a proud man", whereas a head-initial or head-medial adjective phrase follows its noun, e.g. "a man proud of his children". A predicative adjective (phrase), in contrast, appears outside of the noun phrase that it describes, usually after a linking verb, e.g. "The man is proud of his children". There is a tendency to call a phrase an "adjectival phrase" when that phrase is functioning like an adjective phrase, but is not actually headed by an adjective. For example, in "Mr Clinton is a man of wealth", the prepositional