First voyage of James Cook Cook had lost not a single man to scurvy, a remarkable and practically unheard-of achievement in 18th-century long-distance seafaring. Adhering to Royal Navy policy introduced in 1747, Cook persuaded his men to eat foods such as citrus fruits and sauerkraut. At that time it was known that poor diet caused scurvy but not specifically that a vitamin C deficiency was the culprit. Sailors of the day were notoriously against innovation, and at first the men would not eat the sauerkraut. Cook used a "method I never once knew to fail with seamen." He ordered it served to himself and the
Vitamin E E versus placebo. Subset analysis for ischaemic stroke, haemorrhagic stroke, fatal stroke, non-fatal stroke - all no significant difference in risk. Likewise for subset analysis of natural or synthetic vitamin E, or only above or below 300 IU/day, or whether the enrolled people were healthy or considered to be at higher than normal risk. The authors concluded that there was a lack of clinically important benefit of vitamin E supplementation in the prevention of stroke. One large, multi-year study in which post-menopausal women consumed either placebo or 600 IU of natural-sourced vitamin E on alternate days reported no effect on