Hepatic lipase often found bound to HSPG, heparan sulfate proteoglycans (HSPG), keeping HL inactive and unable to bind to HDL (high density lipoprotein) or IDL (intermediate density lipoprotein). When it is free in the bloodstream, however, it is found associated with HDL to maintain it inactive. This is because the triacylglycerides in HDL serve as a substrate, but the lipoprotein contains proteins around the triacylglycerides that can prevent the triacylglycerides from being broken down by HL. One of the principal functions of hepatic lipase is to convert intermediate-density lipoprotein (IDL) to low-density lipoprotein (LDL). Hepatic lipase thus plays an important role in
European Union and its Member States — Certain Measures Relating to the Energy Sector European Union and its Member States — Certain Measures Relating to the Energy Sector European Union and its Member States — Certain Measures Relating to the Energy Sector, DS476, is the formal name of a case brought by the Russian Federation against the European Union and its member states in the World Trade Organization's Dispute Settlement Body. The case was formally initiated with the filing of a complaint by Russia (in WTO terms, a "request for consultations") on April 30, 2014. The dispute concerns the EU's Third Energy Package, which consists of various two EU directives and EU regulations. Russia