Coal tar the European Chemicals Agency. The exact mechanism of action is unknown. Coal tar is a complex mixture of phenols, polycyclic aromatic hydrocarbons (PAHs), and heterocyclic compounds. It is a keratolytic agent, which reduces the growth rate of skin cells and softens the skin's keratin. Coal tar is produced through thermal destruction (pyrolysis) of coal. Its composition varies with the process and type of coal used – lignite, bituminous or anthracite. Coal tar contains approximately 10,000 chemicals, of which only about 50% have been identified. Components include polycyclic aromatic hydrocarbons (4-rings: chrysene, fluoranthene, pyrene, triphenylene, naphthacene, benzanthracene, 5-rings: picene, benzo[a]pyrene, benzo[e]pyrene,
Council at the Highest Court of the Russian Empire In 1786, a senior member of the Collegium of Foreign Affairs, Count Alexander Bezborodko (died in 1799) entered the council. In 1787, the council included: In 1792, the Senate Prosecutor General Alexander Samoylov entered the council. Council at the Highest Court of the Russian Empire The Council at the Highest Court was the highest advisory institution in the Russian Empire that existed since 1768 to 1801. It was created on November 28, 1768 by Catherine the Great as an emergency body to discuss issues related to the conduct of the war with the Ottoman Empire. Initially, it was going irregularly,