Hepatic lipase released into the bloodstream. Another lipoprotein, ApoA-I, which increases release of HDL was shown to have a similar effect by mutating the gene that coded it. Mutated ApoA-I protein caused a decrease in HL release and thus decreased the amount of HL bound to HDL and released into the bloodstream. Hepatic lipase deficiency is a rare, autosomal recessive disorder that results in elevated high density lipoprotein (HDL) cholesterol due to a mutation in the hepatic lipase gene. Clinical features are not well understood and there are no characteristic xanthomas. There is an association with a delay in atherosclerosis in an
Adjective phrase English is that an attributive adjective alone generally precedes the noun, e.g. "a proud man", whereas a head-initial or head-medial adjective phrase follows its noun, e.g. "a man proud of his children". A predicative adjective (phrase), in contrast, appears outside of the noun phrase that it describes, usually after a linking verb, e.g. "The man is proud of his children". There is a tendency to call a phrase an "adjectival phrase" when that phrase is functioning like an adjective phrase, but is not actually headed by an adjective. For example, in "Mr Clinton is a man of wealth", the prepositional