Hepatic stellate cell A decreases progressively in liver injury. The activated stellate cell is also responsible for secreting collagen scar tissue, which can lead to cirrhosis. More recent studies have also shown that in vivo activation of hepatic stellate cells by agents causing liver fibrosis can eventually lead to senescence in these cells, marked by increased SA-beta-galactosidase staining, as well as p53 accumulation and activation of Rb–hallmarks of cellular senescence. Senescent hepatic stellate cells have been demonstrated to limit liver fibrosis by activating interactions with NK cells. The cells of Ito were named for Toshio Ito, a twentieth-century Japanese physician, who introduced a
Adjective phrase phrase "of wealth" modifies "a man" in a manner similar to how an adjective phrase would, and it can be reworded with an adjective, e.g. "Mr Clinton is a wealthy man". A more accurate term for such cases is "phrasal attributive" or "attributive phrase". Constituency tests can also be used to identify adjectives and adjective phrases. Here are the three constituency tests, according to X-bar theory, that prove the adjective phrase is both a constituent, and an AP. Sentence = Sam ordered a very spicy pizza. 1) Coordination tests can be used to confirm if "very spicy" is an adjective