Vitamin C megadosage systemic conditioning ("rebound scurvy"), preoxidant effects, iron overload, reduced absorption of vitamin B12 and copper, increased oxygen demand, and acid erosion of the teeth with chewing ascorbic-acid tablets. In addition, one case has been noted of a woman who had received a kidney transplant followed by high-dose vitamin C and died soon afterwards as a result of calcium oxalate deposits that destroyed her new kidney. Her doctors concluded that high-dose vitamin C therapy should be avoided in patients with renal failure. As discussed previously, vitamin C generally exhibits low toxicity. The (the dose that will kill 50% of a population)
Vitamin D deficiency in Australia individual might need hours to achieve that same desired amount. The strength of the UVB changes throughout the day so time will be change accordingly. There is conflicting evidence to suggest whether obesity contributes to vitamin D deficiency. Obese individuals have an increased risk of being vitamin D deficient likely caused by lack of sun exposure from reduced mobility and or low levels of physical activity. The serum levels of obese Australian were 8.3- 9.5 nmol/L lower in both genders comparable to those of healthy weight ranges. During the AusDiab study conducted throughout Australia serum levels within obese people were