Prairie dog in prairie species such as the black-footed ferret, swift fox, golden eagle, red tailed hawk, American badger, coyote and ferruginous hawk. Other species, such as the golden-mantled ground squirrel, mountain plover, and the burrowing owl, also rely on prairie dog burrows for nesting areas. Even grazing species, such as plains bison, pronghorn, and mule deer have shown a proclivity for grazing on the same land used by prairie dogs. Nevertheless, prairie dogs are often identified as pests and exterminated from agricultural properties because they are capable of damaging crops, as they clear the immediate area around their burrows of most
Black-tailed prairie dog Infanticide partially or totally eliminated 39% (361 individuals) of all litters. Lactating females were the most common killers. Mortality of young was highest due to heavy predation during the winter and early spring following birth. Mortality increases with dispersal from a colony or coterie. Sylvatic plague, caused by the bacterium "Yersinia pestis", can quickly eliminate entire black-tailed prairie dog colonies. Once infected, death occurs within a few days. Black-tailed prairie dogs are also susceptible to diseases transmitted by introduced animals. The most common predators of black-tailed prairie dogs are coyotes ("Canis latrans"), American badgers ("Taxidea taxus"), bobcats ("Lynx rufus"), golden