Hepatic encephalopathy An imbalance between aromatic amino acids (phenylalanine, tryptophan and tyrosine) and branched-chain amino acids (leucine, isoleucine and valine) has been described; this would lead to the generation of false neurotransmitters (such octopamine and 2-hydroxyphenethylamine). Dysregulation of the serotonin system, too, has been reported. Depletion of zinc and accumulation of manganese may play a role. Inflammation elsewhere in the body may precipitate encephalopathy through the action of cytokines and bacterial lipopolysaccharide on astrocytes. The diagnosis of hepatic encephalopathy can only be made in the presence of confirmed liver disease (types A and C) or a portosystemic shunt (type B), as its
Nominalized adjective elaborated by Noam Chomsky, it is suggested that inflected adjectives are more likely to be nominalized because they have overtly-marked φ-features (such as grammatical number and gender), which makes them suitable for use as the complement of a determiner. Determiners with unvalued φ-features must find a complement with a valued φ-feature to meet semantic comprehension. In the diagrams below, the determiner is "the", and its complement is either the noun phrase "poor people" or the nominalized adjective "poor". As the frequency of nominalized adjective use decreased, the frequency of structures using the prop-word "one" increased (phrases such as "the large"