Hepatic veno-occlusive disease some herbal teas), and has been described as part of a rare hereditary disease called "hepatic venoocclusive disease with immunodeficiency" (which results from mutations in the gene coding for a protein called SP110). Features of VODI include weight gain, tender enlargement of the liver, ascites, and yellow discoloration of the skin; it often is associated with acute kidney failure. In the BMT setting, VODI is felt to be due to injury to the hepatic venous endothelium from the conditioning regimen. Toxic agents causing veno-occlusive disease include plants as well as the medication cyclophosphamide. Doppler ultrasound of the liver is typically
Spermaceti organ Spermaceti organ The spermaceti organ is an organ that commonly appears in the heads of toothed whales of the family Physeteroidea, in particular the sperm whale. This organ contains a waxy liquid called spermaceti and is involved in the generation of sound. In the modern day Great Sperm Whale ("Physeter macrocephalus"), the spermaceti organ is far larger in proportion to the animal’s body than what would be explained by simple allometry, and the evolution of the organ has caused changes in basal skull morphology, which may implicate tradeoffs were made that compromised the functionality of other nearby features. The high