Hepatic stellate cell A decreases progressively in liver injury. The activated stellate cell is also responsible for secreting collagen scar tissue, which can lead to cirrhosis. More recent studies have also shown that in vivo activation of hepatic stellate cells by agents causing liver fibrosis can eventually lead to senescence in these cells, marked by increased SA-beta-galactosidase staining, as well as p53 accumulation and activation of Rb–hallmarks of cellular senescence. Senescent hepatic stellate cells have been demonstrated to limit liver fibrosis by activating interactions with NK cells. The cells of Ito were named for Toshio Ito, a twentieth-century Japanese physician, who introduced a
Adjective phrase can be used to confirm if "very spicy" is an adjective phrase. codice_3 "Sam ordered a very spicy pizza that was very spicy." Movement tests not only prove that the constituent moved is a stand-alone constituent, but also proves that this phrase "very spicy" is an AP if drawn in a syntax tree. Thus, because this adjective phrase could be moved to the right (pseudocleft), it's sufficient proof that it is both a constituent and an adjective phrase. Although constituency tests can prove the existence of an AP in a sentence, the meanings of these AP may be ambiguous. This