Scurvy observed in any organism apart from humans and had been considered an exclusively human disease. Certain birds, mammals, and fish are susceptible to scurvy, but pigeons are unaffected, since they can synthesize ascorbic acid internally. Holst and Frølich found they could cure scurvy in guinea pigs with the addition of various fresh foods and extracts. This discovery of an animal experimental model for scurvy, which was made even before the essential idea of "vitamins" in foods had been put forward, has been called the single most important piece of vitamin C research. In 1915, New Zealand troops in the Gallipoli
Vitamin D and neurology vitamin D blood concentration standard for diagnosing hypovitaminosis D does not exist. In the past, hypovitaminosis D has been defined by blood concentrations lower than 20 ng/ mL. However, in more recent literature many researchers have considered 30 ng/ mL to be an insufficient concentration of vitamin D. Subnormal levels of vitamin D are usually caused by poor nutrition or a lack of sun exposure. Risk factors for hypovitaminosis D include premature birth, darker skin pigmentation, obesity, malabsorption, and older age. The brain requires the use of many neurosteroids to develop and function properly. These molecules are often identified as