Hepatic stellate cell A decreases progressively in liver injury. The activated stellate cell is also responsible for secreting collagen scar tissue, which can lead to cirrhosis. More recent studies have also shown that in vivo activation of hepatic stellate cells by agents causing liver fibrosis can eventually lead to senescence in these cells, marked by increased SA-beta-galactosidase staining, as well as p53 accumulation and activation of Rb–hallmarks of cellular senescence. Senescent hepatic stellate cells have been demonstrated to limit liver fibrosis by activating interactions with NK cells. The cells of Ito were named for Toshio Ito, a twentieth-century Japanese physician, who introduced a
Adjective phrase "private" placed in post-object position only creates one interpretation. The structure of adjective phrases (and of all other phrase types) can be represented using tree structures. There are two modern conventions for doing this, constituency-based trees of phrase structure grammars and dependency-based trees of dependency grammars. Both types of trees are produced here. The important aspect of these tree structures—regardless of whether one uses constituency or dependency to show the structure of phrases—is that they are identified as adjective phrases by the label on the top node of each tree. The following trees illustrate head-final adjective phrases, i.e. adjective phrases