Digitalis and blue halos around lights), convulsions, and deadly disturbances of the heart. For a case description, see the paper by Lacassie. Vincent van Gogh's "Yellow Period" may have been influenced by digitalis therapy which, at the time, was thought to control seizures. As noted above, other oculotoxic effects of digitalis include generalized blurry vision, as well as seeing a "halo" around each point of light. In some instances, people have confused digitalis with the relatively harmless comfrey ("Symphytum") plant, which is often brewed into a tea, with fatal consequences. Other fatal accidents involve children drinking the water in a vase
Criticism of the Food and Drug Administration licensing fees to drug manufacturers, which has led to enormous increases in generic drug pricing. In 2013 and 2014, generic drug pricing for over 200 drugs increased over 100%. Many of those drugs had price hikes over 1000%. It has been reported that 75% of the FDA generic drug oversight budget comes directly from private drug companies. A historical example of how the FDA seemingly favors the pharmaceutical industry either from clandestine direct money payments to FDA directors and scientific advisers or other undisclosed or unknown means was seen with the generic drug droperidol. Droperidol was a widely used antiemetic