Anamorphosis before 1583. "The Ambassadors" (c. 1533) by Hans Holbein the Younger is well known for the prominent oblique anamorphic transformation in the painting. In this artwork, a distorted shape lies diagonally across the bottom of the frame. Viewing this from an acute angle transforms it into the plastic image of a human skull. The painting is regarded as a "vanitas" - a meditation on the transience of life - with the skull a symbolic "memento mori". The altered perspective required to see the image reflects the contemporary practice of painting skulls on the reverse of otherwise tranquil paintings. Four centuries
Hans Holbein the Younger that led to Cromwell's downfall. Holbein had deftly survived the downfall of his first two great patrons, Thomas More and Anne Boleyn, but Cromwell's sudden arrest and execution on trumped-up charges of heresy and treason in 1540 undoubtedly damaged his career. Though Holbein retained his position as King's Painter, Cromwell's death left a gap no other patron could fill. It was, ironically, Holbein's portrait of Anne of Cleves which largely led to Cromwell's downfall: furious at being saddled with a wife he found entirely unattractive, the King directed all his anger at Cromwell. Granted, Cromwell had exaggerated her beauty, but