Drug discovery crude preparations are morphine, the active agent in opium, and digoxin, a heart stimulant originating from Digitalis lanata. Organic chemistry also led to the synthesis of many of the natural products isolated from biological sources. Historically, substances, whether crude extracts or purified chemicals, were screened for biological activity without knowledge of the biological target. Only after an active substance was identified was an effort made to identify the target. This approach is known as classical pharmacology, forward pharmacology, or phenotypic drug discovery. Later, small molecules were synthesized to specifically target a known physiological/pathological pathway, avoiding the mass screening of banks
Plant-for-the-Planet President. In addition to the young people, one adult also serves on the board, in a position called the "Planet-for-the-Planet Secretariat". The goal of the Global Board is to give the organisation a focus and make organisation-wide decisions. Coordinated with the organisation, tree planting activities or "parties" are organised by students and children themselves. The students need to find foresters and environmental organisations to supply seedlings, and show them how, where, and when to plant. The funding needed to plant trees comes from individual and corporate donations. Plant-for-the-Planet promises to plant one tree for every Euro donated. The organisation also