Digitalis ill persons, and also during exercise. Digitalis toxicity (also known as digitalis intoxication and digitalism) results from an overdose of digitalis and causes nausea, vomiting and diarrhea, as well as sometimes resulting in xanthopsia (jaundiced or yellow vision) and the appearance of blurred outlines (halos), drooling, abnormal heart rate, cardiac arrhythmias, weakness, collapse, dilated pupils, tremors, seizures, and even death. Bradycardia also occurs. Because a frequent side effect of digitalis is reduction of appetite, some individuals have used the drug as a weight-loss aid. Digitalis is an example of a drug derived from a plant that was formerly used by
Orazio Comes experimentation in that sector. In 1958 the museum of the botanical institute of Portici, hosted in the Royal Palace, was named after him. Orazio Comes Orazio Comes (11 November 1848 – 13 October 1917) was an Italian botanist. From 1906 to 1917 he directed the Agricultural Higher Institute of Portici, in which, thanks to Vincenzo de Cesati, he begun teaching since 1877 as assistant of Nicola Pedicino for the chair of botany, to whom he succeeded in 1880. In his works he studied the physiology and plant pathology of Neapolitan mushrooms and agricultural plants, such as beans and tobacco. From