Mozambique funeral beer poisoning such as digitalis. "Digitalis purpurea", the variety of foxglove flower that is the normal source of digitalis, has become common in the area after introduction by European settlers; the foxglove variety that is native to Africa, "Ceratotheca triloba", resembles the poisonous plant but does not contain digitalis. In the "Forbes" article, David Kroll surmises that while crocodile bile is reputed by local villagers to be highly toxic, this is almost certainly false. Crocodile bile resembles mammalian bile which is universally found in the digestive tract of all higher animals. Mice experimentally fed extracts of the bile did not die, and
New Drug Application Review should complete within 6 months. The decision comes in a "Complete Response Letter". Biologics, such as vaccines and many recombinant proteins used in medical treatments are generally approved by FDA via a Biologic License Application (BLA), rather than an NDA. The manufacture of biologics is considered to differ fundamentally from that of less complex chemicals, requiring a somewhat different approval process. Generic drugs that have already been approved via an NDA submitted by another maker are approved via an Abbreviated New Drug Application (ANDA), which does not require all of the clinical trials normally required for a new drug