Digitalis purpurea" extract containing cardiac glycosides for the treatment of heart conditions was first described in the English-speaking medical literature by William Withering, in 1785, which is considered the beginning of modern therapeutics. It is used to increase cardiac contractility (it is a positive inotrope) and as an antiarrhythmic agent to control the heart rate, particularly in the irregular (and often fast) atrial fibrillation. Digitalis is hence often prescribed for patients in atrial fibrillation, especially if they have been diagnosed with congestive heart failure. Digoxin was approved for heart failure in 1998 under current regulations by the Food and Drug Administration
Nothing comes from nothing a relationship between Maria's theological acumen and this song is accidental or intentional. In the web television series "13 Reasons Why", Ryan Shaver uses this Latin phrase to show Hannah Baker, the main character, that her attempts to write poetry will be useless if she's not willing to put her soul on them, as she is afraid of expressing her most intimate thoughts with strangers. The phrase also appears in H.P. Lovecraft's tale, "The Whisperer in Darkness". Nothing comes from nothing Nothing comes from nothing () is a philosophical expression of a thesis first argued by Parmenides. It is associated