Digitalis digitalis. As a result of increased contractility, stroke volume is increased. Ultimately, digitalis increases cardiac output (Cardiac Output=Stroke Volume x Heart Rate). This is the mechanism that makes this drug a popular treatment for congestive heart failure, which is characterized by low cardiac output. Digitalis also has a vagal effect on the parasympathetic nervous system, and as such is used in re-entrant cardiac arrhythmias and to slow the ventricular rate during atrial fibrillation. The dependence on the vagal effect means digitalis is not effective when a patient has a high sympathetic nervous system drive, which is the case with acutely
Nothing comes from nothing the song "Something Good", which contains the lyrics: "Nothing comes from nothing / nothing ever could". Although the song is devoid of intentional metaphysical connotations, Maria's time in Nonnberg Abbey would have familiarized her with the phrase, which is used in Catholic philosophy to explain God's gratuitous act of , namely, that only the source of all being can give creation its existence. Earlier in the film, in the well-known song "Maria", Maria's fellow nuns lament that there is "many a thing she ought to understand" and that she is "not an asset to the abbey". It is unclear if