Digitalis lactone and a triple-repeating sugar called a glycoside. Digitalis works by inhibiting sodium-potassium ATPase. This results in an increased intracellular concentration of sodium ions and thus a decreased concentration gradient across the cell membrane. This increase in intracellular sodium causes the Na/Ca exchanger to reverse potential, i.e., transition from pumping sodium into the cell in exchange for pumping calcium out of the cell, to pumping sodium out of the cell in exchange for pumping calcium into the cell. This leads to an increase in cytoplasmic calcium concentration, which improves cardiac contractility. Under normal physiological conditions, the cytoplasmic calcium used in
Until She Comes Until She Comes "Until She Comes" is a 1991 song by the English rock band the Psychedelic Furs, taken from their seventh studio album, "World Outside". Written by the Psychedelic Furs and produced by the band with Stephen Street, it was released in June as the album's first single. The 12" version included a remix by Hugh Padgham. The lyrics of "Until She Comes" depict a metaphorical story about drug addiction. The single spent two weeks at No. 1 on the US Modern Rock Tracks chart in September 1991. Author Dave Thompson described the song as "bittersweet" and reminiscent of