Digitalis digitalis. As a result of increased contractility, stroke volume is increased. Ultimately, digitalis increases cardiac output (Cardiac Output=Stroke Volume x Heart Rate). This is the mechanism that makes this drug a popular treatment for congestive heart failure, which is characterized by low cardiac output. Digitalis also has a vagal effect on the parasympathetic nervous system, and as such is used in re-entrant cardiac arrhythmias and to slow the ventricular rate during atrial fibrillation. The dependence on the vagal effect means digitalis is not effective when a patient has a high sympathetic nervous system drive, which is the case with acutely
Where Mathematics Comes From rethink a good deal of the philosophy of mind, epistemology, metaphysics, and the history of ideas. Where Mathematics Comes From Where Mathematics Comes From: How the Embodied Mind Brings Mathematics into Being (hereinafter "WMCF") is a book by George Lakoff, a cognitive linguist, and Rafael E. Núñez, a psychologist. Published in 2000, "WMCF" seeks to found a cognitive science of mathematics, a theory of embodied mathematics based on conceptual metaphor. Mathematics makes up that part of the human conceptual system that is special in the following way: Nikolay Lobachevsky said "There is no branch of mathematics, however abstract, which may