Economics of biodiversity economic loss led by the invasive species and vectors can be reduced. However, even with extensive research into the control species, their use is a risky business, as in the importation of the Cane Toad to control beetles in Queensland. A wide variety of plants, animals and fungi are used as medicine. Wild plant species have been used for medicinal purposes since before the beginning of recorded history. Over 60% of world population depends on the plant medicines for their primary health care. For example, quinine comes from the cinchona tree has been used to treat malaria, digitalis from the
New Drug Application Review should complete within 6 months. The decision comes in a "Complete Response Letter". Biologics, such as vaccines and many recombinant proteins used in medical treatments are generally approved by FDA via a Biologic License Application (BLA), rather than an NDA. The manufacture of biologics is considered to differ fundamentally from that of less complex chemicals, requiring a somewhat different approval process. Generic drugs that have already been approved via an NDA submitted by another maker are approved via an Abbreviated New Drug Application (ANDA), which does not require all of the clinical trials normally required for a new drug