Digitalis purpurea pharmacological forms, extracts of this plant did not frequently cause intoxication because they induced nausea and vomiting within minutes of ingestion, preventing the patient from consuming more. The main toxins in "Digitalis" spp. are the two chemically similar cardiac glycosides: digitoxin and digoxin. Like other cardiac glycosides, these toxins exert their effects by inhibiting the ATPase activity of a complex of transmembrane proteins that form the sodium potassium ATPase pump, (Na/K-ATPase). Inhibition of the Na/K-ATPase in turn causes a rise not only in intracellular Na, but also in calcium, which in turn results in increased force of myocardial muscle contractions.
Cannabis (drug) in the United States and several U.S. states have legalized recreational or medical use. Private use of cannabis was legalized in September 2018 after a unanimous decision by the Constitutional Court in Johannesburg. South Africa is the world's third largest producer of cannabis and the plant has historically been used by traditional healers and Rastafari. Footnotes Citations Cannabis (drug) Cannabis, also known as marijuana among other names, is a psychoactive drug from the "Cannabis" plant used for medical or recreational purposes. The main psychoactive part of cannabis is tetrahydrocannabinol (THC), one of 483 known compounds in the plant, including at