U.S. Route 66 U.S. Route 66 U.S. Route 66 (US 66 or Route 66), also known as the Will Rogers Highway, the Main Street of America or the Mother Road, was one of the original highways in the U.S. Highway System. US 66 was established on November 11, 1926, with road signs erected the following year. The highway, which became one of the most famous roads in the United States, originally ran from Chicago, Illinois, through Missouri, Kansas, Oklahoma, Texas, New Mexico, and Arizona before ending in Santa Monica, California, near Los Angeles, covering a total of . It was recognized in popular
Main Street (Los Angeles) neighborhood of Wilmington, Los Angeles. Nearly 2 miles north at the intersection of Lomita Boulevard, it officially becomes Main Street and enters into the city of Carson. Main Street carries Metro Local lines 10, 33, 48, 55, 68, 76, 83, 92, and 355, as well as Metro Rapid line 733; most of those lines run on Main Street in downtown only, while Line 76 serves Main Street in Northeast Los Angeles and Line 48 in South Los Angeles. Main Street (Los Angeles) Main Street is a major north-south thoroughfare in Los Angeles, California. It serves as the east-west postal divider