Drug discovery crude preparations are morphine, the active agent in opium, and digoxin, a heart stimulant originating from Digitalis lanata. Organic chemistry also led to the synthesis of many of the natural products isolated from biological sources. Historically, substances, whether crude extracts or purified chemicals, were screened for biological activity without knowledge of the biological target. Only after an active substance was identified was an effort made to identify the target. This approach is known as classical pharmacology, forward pharmacology, or phenotypic drug discovery. Later, small molecules were synthesized to specifically target a known physiological/pathological pathway, avoiding the mass screening of banks
Read's Drug Store two walls; preservationists argued that both plans were insufficient. Activists want the building preserved and turned into a civil rights museum. They accuse the city of "demolition by neglect": avoiding minor repairs and allowing the building to collapse in order to make room for development. Support for preserving the building comes from Baltimore Heritage, a non-profit historical preservation group, and the Jewish Museum of Maryland, which celebrates the Nattans' decision to desegregate early. Read's Drug Store Read's Drug Store was a chain of stores based in Baltimore, Maryland. Read's Drug Store was founded by William Read. He sold it to