Digitalis purpurea" extract containing cardiac glycosides for the treatment of heart conditions was first described in the English-speaking medical literature by William Withering, in 1785, which is considered the beginning of modern therapeutics. It is used to increase cardiac contractility (it is a positive inotrope) and as an antiarrhythmic agent to control the heart rate, particularly in the irregular (and often fast) atrial fibrillation. Digitalis is hence often prescribed for patients in atrial fibrillation, especially if they have been diagnosed with congestive heart failure. Digoxin was approved for heart failure in 1998 under current regulations by the Food and Drug Administration
Radioactive contamination from the Rocky Flats Plant tests." As noted by Carl Johnson in Ambio, "Exposures of a large population in the Denver area to plutonium and other radionuclides in the exhaust plumes from the plant date back to 1953." Weapons production at the plant was halted after a combined FBI and EPA raid in 1989 and years of protests. The plant has since been shut down, with its buildings demolished and completely removed from the site. The Rocky Flats Plant was declared a Superfund site in 1989 and began its transformation to a cleanup site in February 1992. Removal of the plant and surface contamination was