Digitalis purpurea" extract containing cardiac glycosides for the treatment of heart conditions was first described in the English-speaking medical literature by William Withering, in 1785, which is considered the beginning of modern therapeutics. It is used to increase cardiac contractility (it is a positive inotrope) and as an antiarrhythmic agent to control the heart rate, particularly in the irregular (and often fast) atrial fibrillation. Digitalis is hence often prescribed for patients in atrial fibrillation, especially if they have been diagnosed with congestive heart failure. Digoxin was approved for heart failure in 1998 under current regulations by the Food and Drug Administration
Mountaineer Power Plant that coal now comes via barge on the Ohio River to an elaborate coal unloading and storage facility.The other portion of coal comes from Big River Mining. An underground coal mine right across the street from the plant. It is mined, cleaned, processed, and shipped by a belt line across the street to the power plant. This single boiler, dual turbine plant produces enough energy to power a city approximately the size of Columbus, Ohio. The plant is connected to the grid by 765 kilovolt transmission lines (the highest rated voltage used in the United States). The location of the