Cardiac glycoside specifically categorized based on the plant they are derived from, as in the following list. For example, cardenolides have been primarily derived from the foxglove plants "Digitalis purpurea" and "Digitalis lanata", while bufadienolides have been derived from the venom of the cane toad "Bufo marinus", from which they receive the “bufo” portion of their name. Below is a full list of plants from which cardiac glycosides can be derived. Cardiac glycosides affect the sodium-potassium ATPase pump in cardiac muscle cells to alter their function. Normally, these sodium-potassium pumps move potassium ions in and sodium ions out. Cardiac glycosides, however, inhibit
The Sun Comes Out Tonight lyrics and album title was Patrick's prior issues with alcoholism and excessive drug use. Patrick explained it as: In my lifetime, the sun definitely came out at night... I’m a recovering drug addict and a recovering alcoholic, but when I was taking drugs, there were a few nights where my blood turned into golden, beautiful sunshine. It was all chemical-based, and I knew it was a lie, but it was completely overwhelming, and it was like the sun had come out at night." Patrick changed the album title from "Gurney" to "The Sun Comes Out Tonight" after feeling so inspired