Digitalis lactone and a triple-repeating sugar called a glycoside. Digitalis works by inhibiting sodium-potassium ATPase. This results in an increased intracellular concentration of sodium ions and thus a decreased concentration gradient across the cell membrane. This increase in intracellular sodium causes the Na/Ca exchanger to reverse potential, i.e., transition from pumping sodium into the cell in exchange for pumping calcium out of the cell, to pumping sodium out of the cell in exchange for pumping calcium into the cell. This leads to an increase in cytoplasmic calcium concentration, which improves cardiac contractility. Under normal physiological conditions, the cytoplasmic calcium used in
Where Mathematics Comes From Where Mathematics Comes From Where Mathematics Comes From: How the Embodied Mind Brings Mathematics into Being (hereinafter "WMCF") is a book by George Lakoff, a cognitive linguist, and Rafael E. Núñez, a psychologist. Published in 2000, "WMCF" seeks to found a cognitive science of mathematics, a theory of embodied mathematics based on conceptual metaphor. Mathematics makes up that part of the human conceptual system that is special in the following way: Nikolay Lobachevsky said "There is no branch of mathematics, however abstract, which may not some day be applied to phenomena of the real world." A common type of conceptual